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Itaru Hamachi - Publications

Affiliations: 
Department of Synthetic Chemistry and Biological Chemistry Kyoto University, Kyōto-shi, Kyōto-fu, Japan 
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201 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Zhu H, Oh JH, Matsuda Y, Mino T, Ishikawa M, Nakamura H, Tsujikawa M, Nonaka H, Hamachi I. Tyrosinase-Based Proximity Labeling in Living Cells and . Journal of the American Chemical Society. PMID 38445591 DOI: 10.1021/jacs.3c13183  0.315
2020 Thimaradka V, Hoon Oh J, Heroven C, Radu Aricescu A, Yuzaki M, Tamura T, Hamachi I. Site-specific covalent labeling of His-tag fused proteins with N-acyl-N-alkyl sulfonamide reagent. Bioorganic & Medicinal Chemistry. 30: 115947. PMID 33360195 DOI: 10.1016/j.bmc.2020.115947  0.327
2020 Zhu H, Hamachi I. Fluorescence imaging of drug target proteins using chemical probes. Journal of Pharmaceutical Analysis. 10: 426-433. PMID 33133726 DOI: 10.1016/J.Jpha.2020.05.013  0.409
2020 Tamura T, Fujisawa A, Tsuchiya M, Shen Y, Nagao K, Kawano S, Tamura Y, Endo T, Umeda M, Hamachi I. Organelle membrane-specific chemical labeling and dynamic imaging in living cells. Nature Chemical Biology. PMID 32958953 DOI: 10.1038/S41589-020-00651-Z  0.323
2020 Zhu H, Tamura T, Fujisawa A, Nishikawa Y, Cheng R, Takato M, Hamachi I. Imaging and profiling of proteins under oxidative conditions in cells and tissues by hydrogen-peroxide-responsive labeling. Journal of the American Chemical Society. PMID 32822179 DOI: 10.1021/Jacs.0C02547  0.352
2020 Shigemitsu H, Kubota R, Nakamura K, Matsuzaki T, Minami S, Aoyama T, Urayama K, Hamachi I. Protein-responsive protein release of supramolecular/polymer hydrogel composite integrating enzyme activation systems. Nature Communications. 11: 3859. PMID 32737298 DOI: 10.1038/S41467-020-17698-0  0.358
2020 Shiraiwa K, Cheng R, Nonaka H, Tamura T, Hamachi I. Chemical Tools for Endogenous Protein Labeling and Profiling. Cell Chemical Biology. PMID 32679042 DOI: 10.1016/J.Chembiol.2020.06.016  0.424
2020 Takano K, Arai S, Sakamoto S, Ushijima H, Ikegami T, Saikusa K, Konuma T, Hamachi I, Akashi S. Screening of protein-ligand interactions under crude conditions by native mass spectrometry. Analytical and Bioanalytical Chemistry. PMID 32328689 DOI: 10.1007/S00216-020-02649-X  0.365
2020 Kubota R, Nakamura K, Torigoe S, Hamachi I. The Power of Confocal Laser Scanning Microscopy in Supramolecular Chemistry: In situ Real-time Imaging of Stimuli-Responsive Multicomponent Supramolecular Hydrogels. Chemistryopen. 9: 67-79. PMID 31988842 DOI: 10.1002/Open.201900328  0.318
2020 Tamura T, Takato M, Shiono K, Hamachi I. Development of a Photoactivatable Proximity Labeling Method for the Identification of Nuclear Proteins Chemistry Letters. 49: 145-148. DOI: 10.1246/Cl.190804  0.368
2019 Tabata S, Jevtic M, Kurashige N, Fuchida H, Kido M, Tani K, Zenmyo N, Uchinomiya S, Harada H, Itakura M, Hamachi I, Shigemoto R, Ojida A. Electron Microscopic Detection of Single Membrane Proteins by a Specific Chemical Labeling. Iscience. 22: 256-268. PMID 31786521 DOI: 10.1016/J.Isci.2019.11.025  0.407
2019 Ueda T, Tamura T, Hamachi I. Development of a cell-based ligand-screening system for identifying Hsp90 inhibitors. Biochemistry. PMID 31592648 DOI: 10.1021/Acs.Biochem.9B00781  0.342
2019 Sakamoto S, Yamaura K, Numata T, Harada F, Amaike K, Inoue R, Kiyonaka S, Hamachi I. Construction of a Fluorescent Screening System of Allosteric Modulators for the GABA Receptor Using a Turn-On Probe. Acs Central Science. 5: 1541-1553. PMID 31572781 DOI: 10.1021/Acscentsci.9B00539  0.346
2019 Kubota R, Kiyonaka S, Hamachi I. On-cell coordination chemistry: Chemogenetic activation of membrane-bound glutamate receptors in living cells. Methods in Enzymology. 622: 411-430. PMID 31155063 DOI: 10.1016/Bs.Mie.2019.02.033  0.323
2019 Masuda M, Matsuo K, Hamachi I. Ligand-Directed N-Sulfonyl Pyridone Chemistry for Selective Native Protein Labeling and Imaging in Live Cell. Methods in Molecular Biology (Clifton, N.J.). 2008: 203-224. PMID 31124099 DOI: 10.1007/978-1-4939-9537-0_16  0.444
2019 Sakamoto S, Kiyonaka S, Hamachi I. Construction of ligand assay systems by protein-based semisynthetic biosensors. Current Opinion in Chemical Biology. 50: 10-18. PMID 30875618 DOI: 10.1016/J.Cbpa.2019.02.011  0.409
2019 Nishikawa Y, Miki T, Awa M, Kuwata K, Tamura T, Hamachi I. Development of a nitric oxide-responsive labeling reagent for proteome analysis of live cells. Acs Chemical Biology. PMID 30715847 DOI: 10.1021/Acschembio.8B01021  0.39
2019 Shindo N, Fuchida H, Sato M, Watari K, Shibata T, Kuwata K, Miura C, Okamoto K, Hatsuyama Y, Tokunaga K, Sakamoto S, Morimoto S, Abe Y, Shiroishi M, Caaveiro JMM, ... ... Hamachi I, et al. Selective and reversible modification of kinase cysteines with chlorofluoroacetamides. Nature Chemical Biology. PMID 30643284 DOI: 10.1038/S41589-018-0204-3  0.313
2019 Zenmyo N, Tokumaru H, Uchinomiya S, Fuchida H, Tabata S, Hamachi I, Shigemoto R, Ojida A. Optimized Reaction Pair of the CysHis Tag and Ni(II)-NTA Probe for Highly Selective Chemical Labeling of Membrane Proteins Bulletin of the Chemical Society of Japan. 92: 995-1000. DOI: 10.1246/Bcsj.20190034  0.44
2018 Tamura T, Hamachi I. Chemistry for Covalent Modification of Endogenous/Native Proteins: From Test Tubes to Complex Biological Systems. Journal of the American Chemical Society. PMID 30592612 DOI: 10.1021/Jacs.8B11747  0.425
2018 Fujisawa A, Tamura T, Yasueda Y, Kuwata K, Hamachi I. Chemical profiling of the endoplasmic reticulum proteome using designer labeling reagents. Journal of the American Chemical Society. PMID 30433779 DOI: 10.1021/Jacs.8B08606  0.367
2018 Sakamoto S, Hamachi I. Recent progress in chemical modification of proteins. Analytical Sciences : the International Journal of the Japan Society For Analytical Chemistry. PMID 30318491 DOI: 10.2116/Analsci.18R003  0.416
2018 Kubota R, Nomura W, Iwasaka T, Ojima K, Kiyonaka S, Hamachi I. Chemogenetic Approach Using Ni(II) Complex-Agonist Conjugates Allows Selective Activation of Class A G-Protein-Coupled Receptors. Acs Central Science. 4: 1211-1221. PMID 30276255 DOI: 10.1021/Acscentsci.8B00390  0.316
2018 Zhu H, Tamura T, Hamachi I. Chemical proteomics for subcellular proteome analysis. Current Opinion in Chemical Biology. 48: 1-7. PMID 30170243 DOI: 10.1016/J.Cbpa.2018.08.001  0.399
2018 Hostachy S, Masuda M, Miki T, Hamachi I, Sagan S, Lequin O, Medjoubi K, Somogyi A, Delsuc N, Policar C. Graftable SCoMPIs enable the labeling and X-ray fluorescence imaging of proteins. Chemical Science. 9: 4483-4487. PMID 29896390 DOI: 10.1039/C8Sc00886H  0.37
2018 Tamura T, Ueda T, Goto T, Tsukidate T, Shapira Y, Nishikawa Y, Fujisawa A, Hamachi I. Rapid labelling and covalent inhibition of intracellular native proteins using ligand-directed N-acyl-N-alkyl sulfonamide. Nature Communications. 9: 1870. PMID 29760386 DOI: 10.1038/S41467-018-04343-0  0.378
2018 Kubota R, Liu S, Shigemitsu H, Nakamura K, Tanaka W, Ikeda M, Hamachi I. Imaging-based study on control factors over self-sorting of supramolecular nanofibers formed from peptide- and lipid-type hydrogelators. Bioconjugate Chemistry. PMID 29742348 DOI: 10.1021/Acs.Bioconjchem.8B00260  0.397
2018 Kiyonaka S, Sakamoto S, Wakayama S, Morikawa Y, Tsujikawa M, Hamachi I. Ligand-directed chemistry of AMPA receptors confers live-cell fluorescent biosensors. Acs Chemical Biology. PMID 29437380 DOI: 10.1021/Acschembio.7B01042  0.398
2018 Ueda T, Tamura T, Hamachi I. In situ Construction of Protein-based Semisynthetic Biosensors. Acs Sensors. PMID 29429332 DOI: 10.1021/Acssensors.7B00894  0.405
2018 Shigemitsu H, Fujisaku T, Tanaka W, Kubota R, Minami S, Urayama K, Hamachi I. An adaptive supramolecular hydrogel comprising self-sorting double nanofibre networks. Nature Nanotechnology. PMID 29311611 DOI: 10.1038/S41565-017-0026-6  0.307
2018 Takaoka Y, Uchinomiya S, Kobayashi D, Endo M, Hayashi T, Fukuyama Y, Hayasaka H, Miyasaka M, Ueda T, Shimada I, Hamachi I. Endogenous Membrane Receptor Labeling by Reactive Cytokines and Growth Factors to Chase Their Dynamics in Live Cells Chem. 4: 1451-1464. DOI: 10.1016/J.Chempr.2018.03.021  0.301
2017 Matsuo K, Nishikawa Y, Masuda M, Hamachi I. Live-Cell Protein Sulfonylation Based on Proximity-driven N-Sulfonyl Pyridone Chemistry. Angewandte Chemie (International Ed. in English). PMID 29193552 DOI: 10.1002/Anie.201707972  0.422
2017 Amaike K, Tamura T, Hamachi I. Recognition-driven chemical labeling of endogenous proteins in multi-molecular crowding in live cells. Chemical Communications (Cambridge, England). PMID 29026906 DOI: 10.1039/C7Cc07177A  0.443
2017 Tamura T, Song Z, Amaike K, Lee S, Yin S, Kiyonaka S, Hamachi I. Affinity-guided oxime chemistry for selective protein acylation in live tissue systems. Journal of the American Chemical Society. PMID 28915034 DOI: 10.1021/Jacs.7B07339  0.455
2017 Delsuc N, Uchinomiya S, Ojida A, Hamachi I. A host-guest system based on collagen-like triple-helix hybridization. Chemical Communications (Cambridge, England). PMID 28604910 DOI: 10.1039/C7Cc03055J  0.306
2017 Wakayama S, Kiyonaka S, Arai I, Kakegawa W, Matsuda S, Ibata K, Nemoto YL, Kusumi A, Yuzaki M, Hamachi I. Chemical labelling for visualizing native AMPA receptors in live neurons. Nature Communications. 8: 14850. PMID 28387242 DOI: 10.1038/Ncomms14850  0.301
2017 Yamaura K, Kiyonaka S, Hamachi I. Construction of Protein-Based Biosensors Using Ligand-Directed Chemistry for Detecting Analyte Binding. Methods in Enzymology. 589: 253-280. PMID 28336066 DOI: 10.1016/Bs.Mie.2017.02.006  0.422
2017 Shigemitsu H, Hamachi I. Design Strategies of Stimuli-Responsive Supramolecular Hydrogels Relying on Structural Analyses and Cell-Mimicking Approaches. Accounts of Chemical Research. PMID 28252940 DOI: 10.1021/Acs.Accounts.7B00070  0.343
2017 Wongkongkatep J, Ojida A, Hamachi I. Fluorescence Sensing of Inorganic Phosphate and Pyrophosphate Using Small Molecular Sensors and Their Applications. Topics in Current Chemistry (Journal). 375: 30. PMID 28251566 DOI: 10.1007/S41061-017-0120-0  0.315
2016 Kiyonaka S, Kubota R, Michibata Y, Sakakura M, Takahashi H, Numata T, Inoue R, Yuzaki M, Hamachi I. Allosteric activation of membrane-bound glutamate receptors using coordination chemistry within living cells. Nature Chemistry. 8: 958-67. PMID 27657873 DOI: 10.1038/Nchem.2554  0.363
2016 Miki T, Awa M, Nishikawa Y, Kiyonaka S, Wakabayashi M, Ishihama Y, Hamachi I. A conditional proteomics approach to identify proteins involved in zinc homeostasis. Nature Methods. PMID 27617391 DOI: 10.1038/Nmeth.3998  0.347
2016 Shigemitsu H, Fujisaku T, Onogi S, Yoshii T, Ikeda M, Hamachi I. Preparation of supramolecular hydrogel-enzyme hybrids exhibiting biomolecule-responsive gel degradation. Nature Protocols. 11: 1744-56. PMID 27560177 DOI: 10.1038/Nprot.2016.099  0.322
2016 Yamaura K, Kiyonaka S, Numata T, Inoue R, Hamachi I. Discovery of allosteric modulators for GABAA receptors by ligand-directed chemistry. Nature Chemical Biology. PMID 27526031 DOI: 10.1038/Nchembio.2150  0.359
2016 Onogi S, Shigemitsu H, Yoshii T, Tanida T, Ikeda M, Kubota R, Hamachi I. In situ real-time imaging of self-sorted supramolecular nanofibres. Nature Chemistry. 8: 743-52. PMID 27442279 DOI: 10.1038/Nchem.2526  0.308
2016 Sueyoshi K, Sumi Y, Inoue Y, Kuroda Y, Ishii K, Nakayama H, Iwabuchi K, Kurishita Y, Shigemitsu H, Hamachi I, Tanaka H. Fluorescence imaging of ATP in neutrophils from patients with sepsis using organelle-localizable fluorescent chemosensors. Annals of Intensive Care. 6: 64. PMID 27422255 DOI: 10.1186/S13613-016-0175-Z  0.31
2016 Yasueda Y, Tamura T, Fujisawa A, Kuwata K, Tsukiji S, Kiyonaka S, Hamachi I. A set of organelle-localizable reactive molecules for mitochondrial chemical proteomics in living cells and brain tissues. Journal of the American Chemical Society. PMID 27228550 DOI: 10.1021/Jacs.6B02254  0.656
2016 Nishikawa Y, Tamura T, Hamachi I. Recent Advance in Organic Chemistry for Protein Labeling under Live Cell Conditions Journal of Synthetic Organic Chemistry, Japan. 74: 521-531. DOI: 10.5059/Yukigoseikyokaishi.74.521  0.368
2016 Yasueda Y, Tamura T, Hamachi I. Nucleus-selective Chemical Proteomics Using Hoechst-tagged Reactive Molecules Chemistry Letters. 45: 265-267. DOI: 10.1246/Cl.151083  0.334
2015 Takaoka Y, Nishikawa Y, Hashimoto Y, Sasaki K, Hamachi I. Ligand-directed dibromophenyl benzoate chemistry for rapid and selective acylation of intracellular natural proteins. Chemical Science. 6: 3217-3224. PMID 28706692 DOI: 10.1039/C5Sc00190K  0.47
2015 Shigemitsu H, Hamachi I. Supramolecular Assemblies Responsive to Biomolecules toward Biological Applications. Chemistry, An Asian Journal. PMID 26152785 DOI: 10.1002/Asia.201500563  0.313
2015 Hayashi T, Yasueda Y, Tamura T, Takaoka Y, Hamachi I. Analysis of Cell-Surface Receptor Dynamics through Covalent Labeling by Catalyst-Tethered Antibody. Journal of the American Chemical Society. 137: 5372-80. PMID 25853648 DOI: 10.1021/Jacs.5B02867  0.379
2015 Kubota R, Hamachi I. Protein recognition using synthetic small-molecular binders toward optical protein sensing in vitro and in live cells. Chemical Society Reviews. 44: 4454-71. PMID 25805520 DOI: 10.1039/C4Cs00381K  0.411
2015 Yoshii T, Onogi S, Shigemitsu H, Hamachi I. Chemically reactive supramolecular hydrogel coupled with a signal amplification system for enhanced analyte sensitivity. Journal of the American Chemical Society. 137: 3360-5. PMID 25679407 DOI: 10.1021/Ja5131534  0.304
2015 Tsukiji S, Hamachi I. Ligand-directed tosyl chemistry for selective native protein labeling in vitro, in cells, and in vivo. Methods in Molecular Biology (Clifton, N.J.). 1266: 243-63. PMID 25560080 DOI: 10.1007/978-1-4939-2272-7_17  0.703
2015 Tamura T, Hamachi I. Labeling proteins by affinity-guided DMAP chemistry. Methods in Molecular Biology (Clifton, N.J.). 1266: 229-42. PMID 25560079 DOI: 10.1007/978-1-4939-2272-7_16  0.42
2015 Takashima I, Kawagoe R, Hamachi I, Ojida A. Development of an AND logic-gate-type fluorescent probe for ratiometric imaging of autolysosome in cell autophagy. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 2038-44. PMID 25470007 DOI: 10.1002/Chem.201405686  0.356
2015 Yasueda Y, Tamura T, Kuwara K, Takaoka Y, Hamachi I. Biomembrane-embedded catalysts for membrane-associated protein labeling on red blood cells Chemistry Letters. 44: 1673-1675. DOI: 10.1246/Cl.150797  0.342
2015 Song Z, Takaoka Y, Kioi Y, Komatsu K, Tamura T, Miki T, Hamachi I. Extended affinity-guided DMAP chemistry with a finely tuned acyl donor for intracellular FKBP12 labeling Chemistry Letters. 44: 333-335. DOI: 10.1246/Cl.141065  0.372
2015 Fuchida H, Tabata S, Shindo N, Takashima I, Leng Q, Hatsuyama Y, Hamachi I, Ojida A. Design of coordination interaction of Zn(II) complex with oligo-aspartate peptide to afford a high-affinity tag-probe pair Bulletin of the Chemical Society of Japan. 88: 784-791. DOI: 10.1246/Bcsj.20150037  0.361
2015 Tiposoth P, Khamsakhon S, Ketsub N, Pongtharangkul T, Takashima I, Ojida A, Hamachi I, Wongkongkatep J. Rapid and quantitative fluorescence detection of pathogenic spore-forming bacteria using a xanthene-Zn(II) complex chemosensor Sensors and Actuators, B: Chemical. 209: 606-612. DOI: 10.1016/J.Snb.2014.11.113  0.325
2014 Ochi R, Nishida T, Ikeda M, Hamachi I. Design of peptide-based bolaamphiphiles exhibiting heat-set hydrogelation via retro-Diels-Alder reaction. Journal of Materials Chemistry. B. 2: 1464-1469. PMID 32261365 DOI: 10.1039/C3Tb21680B  0.305
2014 Yoshii T, Mizusawa K, Takaoka Y, Hamachi I. Intracellular protein-responsive supramolecules: protein sensing and in-cell construction of inhibitor assay system. Journal of the American Chemical Society. 136: 16635-42. PMID 25361466 DOI: 10.1021/Ja508955Y  0.463
2014 Tamura T, Hamachi I. Recent progress in design of protein-based fluorescent biosensors and their cellular applications. Acs Chemical Biology. 9: 2708-17. PMID 25317665 DOI: 10.1021/Cb500661V  0.445
2014 Yamaura K, Kuwata K, Tamura T, Kioi Y, Takaoka Y, Kiyonaka S, Hamachi I. Live cell off-target identification of lapatinib using ligand-directed tosyl chemistry. Chemical Communications (Cambridge, England). 50: 14097-100. PMID 25275302 DOI: 10.1039/C4Cc05885B  0.377
2014 Tsukiji S, Hamachi I. Ligand-directed tosyl chemistry for in situ native protein labeling and engineering in living systems: from basic properties to applications. Current Opinion in Chemical Biology. 21: 136-43. PMID 25129055 DOI: 10.1016/J.Cbpa.2014.07.012  0.705
2014 Miki T, Fujishima SH, Komatsu K, Kuwata K, Kiyonaka S, Hamachi I. LDAI-based chemical labeling of intact membrane proteins and its pulse-chase analysis under live cell conditions. Chemistry & Biology. 21: 1013-22. PMID 25126991 DOI: 10.1016/J.Chembiol.2014.07.013  0.389
2014 Ikeda M, Tanida T, Yoshii T, Kurotani K, Onogi S, Urayama K, Hamachi I. Installing logic-gate responses to a variety of biological substances in supramolecular hydrogel-enzyme hybrids. Nature Chemistry. 6: 511-8. PMID 24848237 DOI: 10.1038/Nchem.1937  0.301
2014 Takahira I, Fuchida H, Tabata S, Shindo N, Uchinomiya S, Hamachi I, Ojida A. Design of a binuclear Ni(II)-iminodiacetic acid (IDA) complex for selective recognition and covalent labeling of His-tag fused proteins. Bioorganic & Medicinal Chemistry Letters. 24: 2855-8. PMID 24835629 DOI: 10.1016/J.Bmcl.2014.04.096  0.413
2014 Nakamura A, Takigawa K, Kurishita Y, Kuwata K, Ishida M, Shimoda Y, Hamachi I, Tsukiji S. Hoechst tagging: a modular strategy to design synthetic fluorescent probes for live-cell nucleus imaging. Chemical Communications (Cambridge, England). 50: 6149-52. PMID 24776726 DOI: 10.1039/C4Cc01753F  0.661
2014 Uchinomiya S, Ojida A, Hamachi I. Peptide tag/probe pairs based on the coordination chemistry for protein labeling. Inorganic Chemistry. 53: 1816-23. PMID 24131471 DOI: 10.1021/Ic401612Z  0.462
2013 Kiyonaka S, Kajimoto T, Sakaguchi R, Shinmi D, Omatsu-Kanbe M, Matsuura H, Imamura H, Yoshizaki T, Hamachi I, Morii T, Mori Y. Genetically encoded fluorescent thermosensors visualize subcellular thermoregulation in living cells. Nature Methods. 10: 1232-8. PMID 24122038 DOI: 10.1038/Nmeth.2690  0.327
2013 Ishida M, Watanabe H, Takigawa K, Kurishita Y, Oki C, Nakamura A, Hamachi I, Tsukiji S. Synthetic self-localizing ligands that control the spatial location of proteins in living cells. Journal of the American Chemical Society. 135: 12684-9. PMID 23941503 DOI: 10.1021/Ja4046907  0.682
2013 Hayashi T, Sun Y, Tamura T, Kuwata K, Song Z, Takaoka Y, Hamachi I. Semisynthetic lectin-4-dimethylaminopyridine conjugates for labeling and profiling glycoproteins on live cell surfaces. Journal of the American Chemical Society. 135: 12252-8. PMID 23889132 DOI: 10.1021/Ja4043214  0.376
2013 Vu NT, Moriwaki Y, Caaveiro JM, Terada T, Tsutsumi H, Hamachi I, Shimizu K, Tsumoto K. Selective binding of antimicrobial porphyrins to the heme-receptor IsdH-NEAT3 of Staphylococcus aureus. Protein Science : a Publication of the Protein Society. 22: 942-53. PMID 23649633 DOI: 10.1002/Pro.2276  0.312
2013 Uchinomiya S, Nonaka H, Wakayama S, Ojida A, Hamachi I. In-cell covalent labeling of reactive His-tag fused proteins. Chemical Communications (Cambridge, England). 49: 5022-4. PMID 23612601 DOI: 10.1039/C3Cc41979G  0.429
2013 Tamura T, Kioi Y, Miki T, Tsukiji S, Hamachi I. Fluorophore labeling of native FKBP12 by ligand-directed tosyl chemistry allows detection of its molecular interactions in vitro and in living cells. Journal of the American Chemical Society. 135: 6782-5. PMID 23611728 DOI: 10.1021/Ja401956B  0.708
2013 Takaoka Y, Kioi Y, Morito A, Otani J, Arita K, Ashihara E, Ariyoshi M, Tochio H, Shirakawa M, Hamachi I. Quantitative comparison of protein dynamics in live cells and in vitro by in-cell (19)F-NMR. Chemical Communications (Cambridge, England). 49: 2801-3. PMID 23440262 DOI: 10.1039/C3Cc39205H  0.383
2013 Takaoka Y, Ojida A, Hamachi I. Protein organic chemistry and applications for labeling and engineering in live-cell systems. Angewandte Chemie (International Ed. in English). 52: 4088-106. PMID 23426903 DOI: 10.1002/Anie.201207089  0.448
2013 Takaoka Y, Fukuyama Y, Matsuo K, Hamachi I. Disassembly-driven turn-on sensing of enzyme activity by substrate-based fluorescent nanoprobe Chemistry Letters. 42: 1426-1428. DOI: 10.1246/Cl.130697  0.332
2013 Matsuo K, Kioi Y, Yasui R, Takaoka Y, Miki T, Fujishima SH, Hamachi I. One-step construction of caged carbonic anhydrase i using a ligand-directed acyl imidazole-based protein labeling method Chemical Science. 4: 2573-2580. DOI: 10.1039/C3Sc50560J  0.371
2013 Takaoka Y, Ojida A, Hamachi I. Organische Proteinchemie und ihre Anwendung für Markierungen und Engineering in Lebendzellsystemen Angewandte Chemie. 125: 4182-4200. DOI: 10.1002/Ange.201207089  0.352
2012 Kurishita Y, Kohira T, Ojida A, Hamachi I. Organelle-localizable fluorescent chemosensors for site-specific multicolor imaging of nucleoside polyphosphate dynamics in living cells. Journal of the American Chemical Society. 134: 18779-89. PMID 23098271 DOI: 10.1021/Ja308754G  0.338
2012 Mizusawa K, Takaoka Y, Hamachi I. Specific cell surface protein imaging by extended self-assembling fluorescent turn-on nanoprobes. Journal of the American Chemical Society. 134: 13386-95. PMID 22809394 DOI: 10.1021/Ja304239G  0.422
2012 Hayashi T, Hamachi I. Traceless affinity labeling of endogenous proteins for functional analysis in living cells. Accounts of Chemical Research. 45: 1460-9. PMID 22680975 DOI: 10.1021/Ar200334R  0.448
2012 Fujishima SH, Yasui R, Miki T, Ojida A, Hamachi I. Ligand-directed acyl imidazole chemistry for labeling of membrane-bound proteins on live cells. Journal of the American Chemical Society. 134: 3961-4. PMID 22352855 DOI: 10.1021/Ja2108855  0.442
2012 Ikeda M, Fukuda K, Tanida T, Yoshii T, Hamachi I. A supramolecular hydrogel containing boronic acid-appended receptor for fluorocolorimetric sensing of polyols with a paper platform. Chemical Communications (Cambridge, England). 48: 2716-8. PMID 22302010 DOI: 10.1039/C2Cc17503G  0.309
2012 Tamura T, Tsukiji S, Hamachi I. Native FKBP12 engineering by ligand-directed tosyl chemistry: labeling properties and application to photo-cross-linking of protein complexes in vitro and in living cells. Journal of the American Chemical Society. 134: 2216-26. PMID 22220821 DOI: 10.1021/Ja209641T  0.714
2012 Fujishima SH, Nonaka H, Uchinomiya SH, Kawase YA, Ojida A, Hamachi I. Design of a multinuclear Zn(II) complex as a new molecular probe for fluorescence imaging of His-tag fused proteins. Chemical Communications (Cambridge, England). 48: 594-6. PMID 22113378 DOI: 10.1039/C1Cc16263B  0.417
2012 Takahashi M, Kawamura A, Kato N, Nishi T, Hamachi I, Ohkanda J. Phosphopeptide-dependent labeling of 14-3-3 ζ proteins by fusicoccin-based fluorescent probes. Angewandte Chemie (International Ed. in English). 51: 509-12. PMID 22105970 DOI: 10.1002/Anie.201106995  0.444
2012 Kittiloespaisan E, Ojida A, Hamachi I, Seetang-Nun Y, Kiatpathomchai W, Wongkongkatep J. Label-free fluorescent detection of loop-mediated isothermal amplification of nucleic acid using pyrophosphate-selective xanthene-based Zn(II)-coordination chemosensor Chemistry Letters. 41: 1666-1668. DOI: 10.1246/Cl.2012.1666  0.361
2011 Tsukiji S, Ishida M, Hamachi I. [Selective chemical labeling and engineering of endogenous cellular proteins]. Seikagaku. the Journal of Japanese Biochemical Society. 83: 746-51. PMID 21942098  0.63
2011 Wang H, Koshi Y, Minato D, Nonaka H, Kiyonaka S, Mori Y, Tsukiji S, Hamachi I. Chemical cell-surface receptor engineering using affinity-guided, multivalent organocatalysts. Journal of the American Chemical Society. 133: 12220-8. PMID 21761940 DOI: 10.1021/Ja204422R  0.671
2011 Sun Y, Takaoka Y, Tsukiji S, Narazaki M, Matsuda T, Hamachi I. Construction of a 19F-lectin biosensor for glycoprotein imaging by using affinity-guided DMAP chemistry. Bioorganic & Medicinal Chemistry Letters. 21: 4393-6. PMID 21737264 DOI: 10.1016/J.Bmcl.2011.06.038  0.603
2011 Komatsu H, Tsukiji S, Ikeda M, Hamachi I. Stiff, multistimuli-responsive supramolecular hydrogels as unique molds for 2D/3D microarchitectures of live cells. Chemistry, An Asian Journal. 6: 2368-75. PMID 21721133 DOI: 10.1002/Asia.201100134  0.617
2011 Takaoka Y, Kiminami K, Mizusawa K, Matsuo K, Narazaki M, Matsuda T, Hamachi I. Systematic study of protein detection mechanism of self-assembling 19F NMR/MRI nanoprobes toward rational design and improved sensitivity. Journal of the American Chemical Society. 133: 11725-31. PMID 21699190 DOI: 10.1021/Ja203996C  0.375
2011 Takaoka Y, Sun Y, Tsukiji S, Hamachi I. Mechanisms of chemical protein 19F-labeling and NMR-based biosensor construction in vitro and in cells using self-assembling ligand-directed tosylate compounds Chemical Science. 2: 511-520. DOI: 10.1039/C0Sc00513D  0.704
2011 Bhuyan M, Katayev E, Stadlbauer S, Nonaka H, Ojida A, Hamachi I, König B. Rigid luminescent bis-zinc(II)-bis-cyclen complexes for the detection of phosphate anions and non-covalent protein labeling in aqueous solution European Journal of Organic Chemistry. 2807-2817. DOI: 10.1002/Ejoc.201100103  0.362
2010 Tamaru S, Ikeda M, Shimidzu Y, Matsumoto S, Takeuchi S, Hamachi I. Fluidic supramolecular nano- and microfibres as molecular rails for regulated movement of nanosubstances. Nature Communications. 1: 20. PMID 20975676 DOI: 10.1038/Ncomms1018  0.306
2010 Ikeda M, Ochi R, Hamachi I. Supramolecular hydrogel-based protein and chemosensor array. Lab On a Chip. 10: 3325-34. PMID 20862441 DOI: 10.1039/C004908E  0.409
2010 Kurishita Y, Kohira T, Ojida A, Hamachi I. Rational design of FRET-based ratiometric chemosensors for in vitro and in cell fluorescence analyses of nucleoside polyphosphates. Journal of the American Chemical Society. 132: 13290-9. PMID 20812684 DOI: 10.1021/Ja103615Z  0.396
2010 Nonaka H, Fujishima SH, Uchinomiya SH, Ojida A, Hamachi I. Selective covalent labeling of tag-fused GPCR proteins on live cell surface with a synthetic probe for their functional analysis. Journal of the American Chemical Society. 132: 9301-9. PMID 20568758 DOI: 10.1021/Ja910703V  0.451
2010 Mizusawa K, Ishida Y, Takaoka Y, Miyagawa M, Tsukiji S, Hamachi I. Disassembly-driven turn-on fluorescent nanoprobes for selective protein detection. Journal of the American Chemical Society. 132: 7291-3. PMID 20462178 DOI: 10.1021/Ja101879G  0.697
2010 Taki M, Iyoshi S, Ojida A, Hamachi I, Yamamoto Y. Development of highly sensitive fluorescent probes for detection of intracellular copper(I) in living systems. Journal of the American Chemical Society. 132: 5938-9. PMID 20377254 DOI: 10.1021/Ja100714P  0.357
2010 Ojida A, Fujishima SH, Honda K, Nonaka H, Uchinomiya SH, Hamachi I. Binuclear Ni(II)-DpaTyr complex as a high affinity probe for an oligo-aspartate Tag tethered to proteins. Chemistry, An Asian Journal. 5: 877-86. PMID 20143369 DOI: 10.1002/Asia.200900362  0.324
2010 Ikeda M, Ochi R, Wada A, Hamachi I. Supramolecular hydrogel capsule showing prostate specific antigen-responsive function for sensing and targeting prostate cancer cells Chemical Science. 1: 491-498. DOI: 10.1039/C0Sc00278J  0.319
2009 Takaoka Y, Sakamoto T, Tsukiji S, Narazaki M, Matsuda T, Tochio H, Shirakawa M, Hamachi I. Self-assembling nanoprobes that display off/on 19F nuclear magnetic resonance signals for protein detection and imaging. Nature Chemistry. 1: 557-61. PMID 21378937 DOI: 10.1038/Nchem.365  0.642
2009 Nonaka H, Fujishima SH, Uchinomiya SH, Ojida A, Hamachi I. FLAG-tag selective covalent protein labeling via a binding-induced acyl-transfer reaction. Bioorganic & Medicinal Chemistry Letters. 19: 6696-9. PMID 19837586 DOI: 10.1016/J.Bmcl.2009.09.122  0.426
2009 Uchinomiya SH, Nonaka H, Fujishima SH, Tsukiji S, Ojida A, Hamachi I. Site-specific covalent labeling of His-tag fused proteins with a reactive Ni(II)-NTA probe. Chemical Communications (Cambridge, England). 5880-2. PMID 19787128 DOI: 10.1039/B912025D  0.672
2009 Wang H, Nakata E, Hamachi I. Recent progress in strategies for the creation of protein-based fluorescent biosensors. Chembiochem : a European Journal of Chemical Biology. 10: 2560-77. PMID 19693761 DOI: 10.1002/cbic.200900249  0.337
2009 Sakamoto T, Inoue MA, Ojida A, Hamachi I. Real-time fluorescence monitoring of GSK3beta-catalyzed phosphoryation by use of a BODIPY-based Zn(II)-Dpa chemosensor. Bioorganic & Medicinal Chemistry Letters. 19: 4175-7. PMID 19546004 DOI: 10.1016/J.Bmcl.2009.05.121  0.354
2009 Tsukiji S, Wang H, Miyagawa M, Tamura T, Takaoka Y, Hamachi I. Quenched ligand-directed tosylate reagents for one-step construction of turn-on fluorescent biosensors. Journal of the American Chemical Society. 131: 9046-54. PMID 19499918 DOI: 10.1021/Ja902486C  0.712
2009 Ishida Y, Inoue MA, Inoue T, Ojida A, Hamachi I. Sequence selective dual-emission detection of (i, i + 1) bis-phosphorylated peptide using diazastilbene-type Zn(II)-Dpa chemosensor. Chemical Communications (Cambridge, England). 2848-50. PMID 19436886 DOI: 10.1039/B905814A  0.317
2009 Ojida A, Sakamoto T, Inoue MA, Fujishima SH, Lippens G, Hamachi I. Fluorescent BODIPY-based Zn(II) complex as a molecular probe for selective detection of neurofibrillary tangles in the brains of Alzheimer's disease patients. Journal of the American Chemical Society. 131: 6543-8. PMID 19368380 DOI: 10.1021/Ja9008369  0.373
2009 Wada A, Tamaru S, Ikeda M, Hamachi I. MCM-enzyme-supramolecular hydrogel hybrid as a fluorescence sensing material for polyanions of biological significance. Journal of the American Chemical Society. 131: 5321-30. PMID 19351208 DOI: 10.1021/Ja900500J  0.376
2009 Tsukiji S, Miyagawa M, Takaoka Y, Tamura T, Hamachi I. Ligand-directed tosyl chemistry for protein labeling in vivo. Nature Chemical Biology. 5: 341-3. PMID 19330012 DOI: 10.1038/Nchembio.157  0.699
2009 Sakamoto T, Ojida A, Hamachi I. Molecular recognition, fluorescence sensing, and biological assay of phosphate anion derivatives using artificial Zn(II)-Dpa complexes. Chemical Communications (Cambridge, England). 141-52. PMID 19099054 DOI: 10.1039/B812374H  0.396
2008 Ikeda M, Ueno S, Matsumoto S, Shimizu Y, Komatsu H, Kusumoto K, Hamachi I. Three-dimensional encapsulation of live cells by using a hybrid matrix of nanoparticles in a supramolecular hydrogel. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 10808-15. PMID 18942699 DOI: 10.1002/Chem.200801144  0.306
2008 Taki M, Desaki M, Ojida A, Iyoshi S, Hirayama T, Hamachi I, Yamamoto Y. Fluorescence imaging of intracellular cadmium using a dual-excitation ratiometric chemosensor. Journal of the American Chemical Society. 130: 12564-5. PMID 18761452 DOI: 10.1021/Ja803429Z  0.315
2008 Ojida A, Takashima I, Kohira T, Nonaka H, Hamachi I. Turn-on fluorescence sensing of nucleoside polyphosphates using a xanthene-based Zn(II) complex chemosensor. Journal of the American Chemical Society. 130: 12095-101. PMID 18700758 DOI: 10.1021/Ja803262W  0.378
2008 Wakabayashi H, Miyagawa M, Koshi Y, Takaoka Y, Tsukiji S, Hamachi I. Affinity-labeling-based introduction of a reactive handle for natural protein modification. Chemistry, An Asian Journal. 3: 1134-9. PMID 18494012 DOI: 10.1002/Asia.200800057  0.706
2008 Matsumoto S, Yamaguchi S, Ueno S, Komatsu H, Ikeda M, Ishizuka K, Iko Y, Tabata KV, Aoki H, Ito S, Noji H, Hamachi I. Photo gel-sol/sol-gel transition and its patterning of a supramolecular hydrogel as stimuli-responsive biomaterials. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 3977-86. PMID 18335444 DOI: 10.1002/Chem.200701904  0.447
2008 Koshi Y, Nakata E, Miyagawa M, Tsukiji S, Ogawa T, Hamachi I. Target-specific chemical acylation of lectins by ligand-tethered DMAP catalysts. Journal of the American Chemical Society. 130: 245-51. PMID 18076168 DOI: 10.1021/Ja075684Q  0.684
2008 Nakata E, Wang H, Hamachi I. Ratiometric fluorescent biosensor for real-time and label-free monitoring of fine saccharide metabolic pathways. Chembiochem : a European Journal of Chemical Biology. 9: 25-8. PMID 18061910 DOI: 10.1002/Cbic.200700364  0.314
2008 Yamaguchi S, Matsumoto S, Ishizuka K, Iko Y, Tabata KV, Arata HF, Fujita H, Noji H, Hamachi I. Thermally responsive supramolecular nanomeshes for on/off switching of the rotary motion of F1-ATPase at the single-molecule level. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 1891-6. PMID 18058783 DOI: 10.1002/Chem.200701285  0.421
2008 Kohira T, Takashima I, Nonaka H, Ojida A, Hamachi I. Real-time off/on-mode fluorescence assay for enzyme reactions involving nucleoside polyphosphates by use of a xanthene Zn II-Dpa chemosensor Chemistry Letters. 37: 1164-1165. DOI: 10.1246/Cl.2008.1164  0.321
2007 Nonaka H, Tsukiji S, Ojida A, Hamachi I. Non-enzymatic covalent protein labeling using a reactive tag. Journal of the American Chemical Society. 129: 15777-9. PMID 18052248 DOI: 10.1021/Ja074176D  0.699
2007 Tsukiji S, Hamachi I. [Fluorescent labeling of proteins by in-cell-directed chemistry]. Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme. 52: 1581-7. PMID 18051383  0.307
2007 Honda K, Fujishima SH, Ojida A, Hamachi I. Pyrene excimer-based dual-emission detection of a oligoaspartate tag-fused protein by using a Zn(II)-DpaTyr probe. Chembiochem : a European Journal of Chemical Biology. 8: 1370-2. PMID 17590878 DOI: 10.1002/Cbic.200700146  0.357
2007 Anai T, Nakata E, Koshi Y, Ojida A, Hamachi I. Design of a hybrid biosensor for enhanced phosphopeptide recognition based on a phosphoprotein binding domain coupled with a fluorescent chemosensor. Journal of the American Chemical Society. 129: 6232-9. PMID 17441721 DOI: 10.1021/Ja0693284  0.387
2007 Nakata E, Tsukiji S, Hamachi I. Development of new methods to introduce unnatural functional molecules into native proteins for protein engineering Bulletin of the Chemical Society of Japan. 80: 1268-1279. DOI: 10.1246/Bcsj.80.1268  0.685
2007 Honda K, Fujishima S, Ojida A, Hamachi I. Cover Picture: Pyrene Excimer-Based Dual-Emission Detection of a Oligoaspartate Tag-Fused Protein by Using a ZnII–DpaTyr Probe (ChemBioChem 12/2007) Chembiochem. 8: 1333-1333. DOI: 10.1002/Cbic.200790037  0.354
2006 Ojida A, Miyahara Y, Wongkongkatep J, Tamaru S, Sada K, Hamachi I. Design of dual-emission chemosensors for ratiometric detection of ATP derivatives. Chemistry, An Asian Journal. 1: 555-63. PMID 17441093 DOI: 10.1002/Asia.200600137  0.357
2006 Honda K, Nakata E, Ojida A, Hamachi I. Ratiometric fluorescence detection of a tag fused protein using the dual-emission artificial molecular probe. Chemical Communications (Cambridge, England). 4024-6. PMID 17003887 DOI: 10.1039/B608684E  0.406
2006 Ojida A, Honda K, Shinmi D, Kiyonaka S, Mori Y, Hamachi I. Oligo-Asp tag/Zn(II) complex probe as a new pair for labeling and fluorescence imaging of proteins. Journal of the American Chemical Society. 128: 10452-9. PMID 16895410 DOI: 10.1021/Ja0618604  0.436
2006 Takaoka Y, Tsutsumi H, Kasagi N, Nakata E, Hamachi I. One-pot and sequential organic chemistry on an enzyme surface to tether a fluorescent probe at the proximity of the active site with restoring enzyme activity. Journal of the American Chemical Society. 128: 3273-80. PMID 16522109 DOI: 10.1021/Ja057926X  0.38
2006 Ojida A, Inoue MA, Mito-oka Y, Tsutsumi H, Sada K, Hamachi I. Effective disruption of phosphoprotein-protein surface interaction using Zn(II) dipicolylamine-based artificial receptors via two-point interaction. Journal of the American Chemical Society. 128: 2052-8. PMID 16464107 DOI: 10.1021/Ja056585K  0.381
2006 Wongkongkatep J, Miyahara Y, Ojida A, Hamachi I. Label-free, real-time glycosyltransferase assay based on a fluorescent artificial chemosensor. Angewandte Chemie (International Ed. in English). 45: 665-8. PMID 16365842 DOI: 10.1002/Anie.200503107  0.338
2006 Ojida A, Hamachi I. Design and synthesis of bis(Zn(II)-dipicolylamine)-based fluorescent artificial chemosensors for phosphorylated proteins/peptides Bulletin of the Chemical Society of Japan. 79: 35-46. DOI: 10.1246/Bcsj.79.35  0.405
2005 Tamaru S, Kiyonaka S, Hamachi I. Three distinct read-out modes for enzyme activity can operate in a semi-wet supramolecular hydrogel. Chemistry (Weinheim An Der Bergstrasse, Germany). 11: 7294-304. PMID 16196071 DOI: 10.1002/Chem.200500666  0.329
2005 Nakata E, Koshi Y, Koga E, Katayama Y, Hamachi I. Double-modification of lectin using two distinct chemistries for fluorescent ratiometric sensing and imaging saccharides in test tube or in cell. Journal of the American Chemical Society. 127: 13253-61. PMID 16173755 DOI: 10.1021/Ja052731A  0.394
2005 Koshi Y, Nakata E, Hamachi I. Luminescent saccharide biosensor by using lanthanide-bound lectin labeled with fluorescein. Chembiochem : a European Journal of Chemical Biology. 6: 1349-52. PMID 16052613 DOI: 10.1002/Cbic.200500072  0.329
2005 Tamaru SI, Yamaguchi S, Hamachi I. Simple and practical semi-wet protein/peptide array utilizing a micelle-mixed agarose hydrogel Chemistry Letters. 34: 294-295. DOI: 10.1246/Cl.2005.294  0.322
2005 Ojida A, Tsutsumi H, Kasagi N, Hamachi I. Suzuki coupling for protein modification Tetrahedron Letters. 46: 3301-3305. DOI: 10.1016/J.Tetlet.2005.03.094  0.391
2005 Hayashida O, Hamachi I. Cyclophane-lectin conjugates as a new class of water-soluble host Journal of Inclusion Phenomena. 53: 57-61. DOI: 10.1007/S10847-005-0993-3  0.342
2004 Ojida A, Miyahara Y, Kohira T, Hamachi I. Recognition and Fluorescence Sensing of Specific Amino Acid Residue on Protein Surface Using Designed Molecules Biopolymers - Peptide Science Section. 76: 177-184. PMID 15054897 DOI: 10.1002/Bip.10574  0.399
2004 Ojida A, Mito-Oka Y, Sada K, Hamachi I. Molecular Recognition and Fluorescence Sensing of Monophosphorylated Peptides in Aqueous Solution by Bis(zinc(II)-dipicolylamine)-Based Artificial Receptors Journal of the American Chemical Society. 126: 2454-2463. PMID 14982454 DOI: 10.1021/Ja038277X  0.378
2004 Nakata E, Nagase T, Shinkai S, Hamachi I. Coupling a Natural Receptor Protein with an Artificial Receptor to Afford a Semisynthetic Fluorescent Biosensor Journal of the American Chemical Society. 126: 490-495. PMID 14719946 DOI: 10.1021/Ja035631I  0.53
2004 Kiyonaka S, Sada K, Yoshimura I, Shinkai S, Kato N, Hamachi I. Semi-wet peptide/protein array using supramolecular hydrogel Nature Materials. 3: 58-64. PMID 14661016 DOI: 10.1038/Nmat1034  0.512
2004 Ojida A, Kohira T, Hamachi I. Phosphoprotein-selective recognition and staining in SDS-PAGE by bis-Zn(II)-dipycolylamine-appended anthracene Chemistry Letters. 33: 1024-1025. DOI: 10.1246/Cl.2004.1024  0.338
2004 Hayashida O, Hamachi I. Fluorophore Appended Saccharide Cyclophane: Self-Association, Fluorescent Properties, Heterodimers with Cyclodextrins, and Cross-Linking Behavior with Peanut Agglutinin of Dansyl-Modified Saccharide Cyclophane Journal of Organic Chemistry. 69: 3509-3516. DOI: 10.1021/Jo0496852  0.336
2003 Nagase T, Nakata E, Shinkai S, Hamachi I. Construction of artificial signal transducers on a lectin surface by post-photoaffinity-labeling modification for fluorescent saccharide biosensors Chemistry - a European Journal. 9: 3660-3669. PMID 12898693 DOI: 10.1002/Chem.200304925  0.448
2003 Kiyonaka S, Shinkai S, Hamachi I. Combinatorial library of low molecular-weight organo- and hydrogelators based on glycosylated amino acid derivatives by solid-phase synthesis Chemistry - a European Journal. 9: 976-983. PMID 12584714 DOI: 10.1002/Chem.200390120  0.458
2003 Hayashida O, Hamachi I. New Supramolecular Approach for Saccharide-directed Chemical Modification of Concanavalin A Chemistry Letters. 32: 632-633. DOI: 10.1246/Cl.2003.632  0.398
2003 Kiyonaka S, Shinkai S, Hamachi I. Cover Picture: Combinatorial Library of Low Molecular-Weight Organo- and Hydrogelators Based on Glycosylated Amino Acid Derivatives by Solid-Phase Synthesis (Chem. Eur. J. 4/2003) Chemistry - a European Journal. 9: 815-815. DOI: 10.1002/Chem.200390105  0.36
2002 Kiyonaka S, Sugiyasu K, Shinkai S, Hamachi I. First thermally responsive supramolecular polymer based on glycosylated amino acid Journal of the American Chemical Society. 124: 10954-10955. PMID 12224923 DOI: 10.1021/Ja027277E  0.409
2002 Ojida A, Mito-Oka Y, Inoue MA, Hamachi I. First artificial receptors and chemosensors toward phosphorylated peptide in aqueous solution Journal of the American Chemical Society. 124: 6256-6258. PMID 12033851 DOI: 10.1021/Ja025761B  0.31
2002 Tsukiji S, Hamachi I. Semisynthetic hemoproteins using cofactor engineering: Toward supramolecular protein-based photosynthetic system Supramolecular Chemistry. 14: 133-142. DOI: 10.1080/10610270290026031  0.611
2002 Ojida A, Park SK, Mito-Oka Y, Hamachi I. Efficient fluorescent ATP-sensing based on coordination chemistry under aqueous neutral conditions Tetrahedron Letters. 43: 6193-6195. DOI: 10.1016/S0040-4039(02)01317-5  0.334
2001 Takashima H, Hu Y, Sano K, Shinkai S, Oishi S, Hamachi I. Supramolecular Construction of Covalently and Noncovalently-linked Photoinduced Electron Transfer Systems in Myoglobin Scaffold Electrochemistry. 69: 942-945. DOI: 10.5796/Electrochemistry.69.942  0.412
2001 Hamachi I, Kasagi N, Kiyonaka S, Nagase T, Mito-Oka Y, Shinkai S. Pd(en) as a sequence-selective molecular pinch for α-helical peptides Chemistry Letters. 16-17. DOI: 10.1246/Cl.2001.16  0.304
2001 Nagase T, Shinkai S, Hamachi I. Post-photoaffinity labeling modification using aldehyde chemistry to produce a fluorescent lectin toward saccharide-biosensors Chemical Communications. 229-230. DOI: 10.1039/B008323M  0.458
2001 Mito-oka Y, Tsukiji S, Hiraoka T, Kasagi N, Shinkai S, Hamachi I. Zn(II) dipicolylamine-based artificial receptor as a new entry for surface recognition of α-helical peptides in aqueous solution Tetrahedron Letters. 42: 7059-7062. DOI: 10.1016/S0040-4039(01)01408-3  0.659
2001 Hamachi I, Kiyonaka S, Shinkai S. Solid-phase lipid synthesis (SPLS)-2: Incidental discovery of organogelators based on artificial glycolipids Tetrahedron Letters. 42: 6141-6145. DOI: 10.1016/S0040-4039(01)01013-9  0.396
2000 Hamachi I, Watanabe JI, Eboshi R, Hiraoka T, Shinkai S. Incorporation of artificial receptors into a protein/peptide surface: A strategy for on/off type of switching of semisynthetic enzymes Biopolymers - Peptide Science Section. 55: 459-468. PMID 11304673 DOI: 10.1002/1097-0282(2000)55:6<459::Aid-Bip1021>3.0.Co;2-R  0.505
2000 Hu YZ, Takashima H, Tsukiji S, Shinkai S, Nagamune T, Oishi S, Hamachi I. Direct comparison of electron transfer properties of two distinct semisynthetic triads with non-protein based triad: Unambiguous experimental evidences on protein matrix effects Chemistry - a European Journal. 6: 1907-1916. PMID 10894389 DOI: 10.1002/1521-3765(20000602)6:11<1907::Aid-Chem1907>3.0.Co;2-9  0.683
2000 Hamachi I, Takashima H, Hu YZ, Shinkai S, Oishi S. Cyclodextrin-appended myoglobin as a tool for construction of a donor–sensitizer–acceptor triad on a protein surface Chemical Communications. 1127-1128. DOI: 10.1039/B001997F  0.37
2000 Kobayashi H, Nakashima K, Ohshima E, Hisaeda Y, Hamachi I, Shinkai S. Novel saccharide-induced conformational changes in a boronic acid-appended poly(L-lysine) as detected by circular dichroism and fluorescence Journal of the Chemical Society-Perkin Transactions 1. 997-1002. DOI: 10.1039/A909822D  0.318
2000 Hamachi I, Eboshi R, Watanabe JI, Shinkai S. Guest-induced umpolung on a protein surface: A strategy for regulation of enzymatic activity [12] Journal of the American Chemical Society. 122: 4530-4531. DOI: 10.1021/Ja9944857  0.452
2000 Hu YZ, Tsukiji S, Shinkai S, Oishi S, Hamachi I. Construction of artificial photosynthetic reaction centers on a protein surface: Vectorial, multistep, and proton-coupled electron transfer for long- lived charge separation Journal of the American Chemical Society. 122: 241-253. DOI: 10.1021/Ja991406I  0.663
2000 Hamachi I, Nagase T, Shinkai S. A general semisynthetic method for fluorescent saccharide-biosensors based on a lectin [36] Journal of the American Chemical Society. 122: 12065-12066. DOI: 10.1021/Ja002044D  0.387
2000 Kobayashi H, Nakashima K, Ohshima E, Hisaeda Y, Hamachi I, Shinkai S. Novel saccharide-induced conformational changes in a boronic acid-appended poly(L-lysine) as detected by circular dichroism and fluorescence Journal of the Chemical Society. Perkin Transactions 2. 997-1002.  0.362
2000 Hamachi I, Takashima H, Hu YZ, Shinkai S, Oishi S. Cyclodextrin-appended myoglobin as a tool for construction of a donor- sensitizer-acceptor triad on a protein surface Chemical Communications. 1127-1128.  0.383
2000 Murakami H, Okusa Y, Kiyonaka S, Hamachi I, Shinkai S, Nakashima N. The synthesis of a reconstituted C60-modified protein Chemistry Letters. 46-47.  0.37
1999 Hamachi I, Tsukiji S, Shinkai S, Oishi S. Direct observation of the ferric-porphyrin cation radical as an intermediate in the phototriggered oxidation of ferric- to ferryl-heme tethered to Ru(bpy)3 in reconstituted myoglobin Journal of the American Chemical Society. 121: 5500-5506. DOI: 10.1021/Ja984199F  0.637
1999 Kawaguchi M, Ikeda A, Hamachi I, Shinkai S. Metal-induced conformational changes in calix[n]arenes can control the electron-transfer efficiency between porphyrin and [60]fullerene in an on-off manner Tetrahedron Letters. 40: 8245-8249. DOI: 10.1016/S0040-4039(99)01750-5  0.309
1999 Hamachi I, Shinkai S. Chemical Modification of the Structures and Functions of Proteins by the Cofactor Reconstitution Method European Journal of Organic Chemistry. 1999: 539-549. DOI: 10.1002/(Sici)1099-0690(199903)1999:3<539::Aid-Ejoc539>3.0.Co;2-F  0.527
1999 Hu YZ, Tsukiji S, Shinkai S, Hamachi I. A convenient synthesis of a Ru(bpy)3-based catenane-type triad and its incorporation into a protein scaffold Chemistry Letters. 517-518.  0.631
1999 Hamachi I, Takashima H, Tsukiji S, Shinkai S, Nagamune T, Oishi S. Electron transfer from Zn-Protoporphyrin IX to ruthenium ammine attached at His63 of reconstituted cytochrome b562 Chemistry Letters. 551-552.  0.564
1999 Takashima H, Shinkai S, Hamachi I. Ru(bpy)3-based artificial receptors toward a protein surface: Selective binding and efficient photoreduction of cytochrome c Chemical Communications. 2345-2346.  0.39
1998 Hamachi I, Tanaka S, Tsukiji S, Shinkai S, Oishi S. Design and Semisynthesis of Photoactive Myoglobin Bearing Ruthenium Tris(2,2‘-bipyridine) Using Cofactor-Reconstitution Inorganic Chemistry. 37: 4380-4388. PMID 11670575 DOI: 10.1021/Ic971507M  0.677
1998 Hamachi I, Hiraoka T, Yamada Y, Shinkai S. Photoswitching of the Enzymatic Activity of Semisynthetic Ribonuclease S′ Bearing Phenylazophenylalanine at a Specific Site Chemistry Letters. 27: 537-538. DOI: 10.1246/Cl.1998.537  0.411
1998 Mizuno T, Takeuchi M, Hamachi I, Nakashima K, Shinkai S. A boronic acid-diol interaction is useful for chiroselective transcription of the sugar structure to the Δ- Versus Λ-[CoIII(bpy)3]3+ ratio Journal of the Chemical Society. Perkin Transactions 2. 2281-2288. DOI: 10.1039/A803382J  0.313
1998 Hamachi I, Matsugi T, Wakigawa K, Shinkai S. Design and Synthesis of a Transition Metal Responsive Semisynthetic Myoglobin-Bearing Iminodiacetic Acid Moiety Inorganic Chemistry. 37: 1592-1597. DOI: 10.1021/Ic961474V  0.307
1998 Hamachi I, Tanaka S, Tsukiji S, Shinkai S, Oishi S. Design and Semisynthesis of Photoactive Myoglobin Bearing Ruthenium Tris(2,2′-bipyridine) Using Cofactor-Reconstitution Inorganic Chemistry. 37: 4380-4388.  0.562
1997 Hamachi I, Nagase T, Tajiri Y, Shinkai S. Incorporation of an artificial receptor into a native protein: New strategy for the design of semisynthetic enzymes with allosteric properties Bioconjugate Chemistry. 8: 862-868. PMID 9404659 DOI: 10.1021/Bc970055Z  0.381
1997 Takeuchi M, Kijima H, Hamachi I, Shinkai S. A Novel Sugar Sensing System Designed with a Cooperative Action of a Boronic-Acid-Appended Zinc Porphyrin and a 3-Pyridylboronic Acid Axial Ligand Bulletin of the Chemical Society of Japan. 70: 699-705. DOI: 10.1246/Bcsj.70.699  0.373
1997 Mizuno T, Takeuchi M, Hamachi I, Nakashima K, Shinkai S. Chiroselective transcription of the sugar structure to Δ- or Λ-[CoIII(bpy)3]3+ using a boronic acid-sugar template interaction Chemical Communications. 1793-1794. DOI: 10.1039/A704041E  0.351
1997 Hamachi I, Tajiri Y, Nagase T, Shinkai S. Design and Synthesis of Sugar-Responsive Semiartificial Myoglobin Triggered by Modulation of Apoprotein–Cofactor Interactions Chemistry - a European Journal. 3: 1025-1031. DOI: 10.1002/Chem.19970030707  0.396
1997 Hamachi I, Tanaka S, Tsukiji S, Shinkai S, Shimizu M, Nagamune T. Photocontrol of the redox state of ruthenium-tris(bipyridine)-appended cytochrome b562 Chemical Communications. 1735-1736.  0.55
1996 Hamachi I, Tsukiji S, Tanaka S, Shinkai S. Efficient Photogeneration of Oxidizing (Compound II-like) Species of Semisynthetic Myoglobin Appending Ruthenium Tris(2,2′-bipyridine) Chemistry Letters. 25: 751-752. DOI: 10.1246/Cl.1996.751  0.617
1996 Hamachi I, Matsugi T, Tanaka S, Shinkai S. Facilitated Photoreduction of Ruthenium Bis(4′-methylterpyridine) Pendant Myoglobin Bulletin of the Chemical Society of Japan. 69: 1657-1661. DOI: 10.1246/Bcsj.69.1657  0.358
1996 Hamachi I, Matsugi T, Shinkai S. Transition-metals facilitated electron transfer of semisynthetic myoglobin bearing bis(iminodiacetic acid) moiety Tetrahedron Letters. 37: 9233-9236. DOI: 10.1016/S0040-4039(96)02192-2  0.335
1996 Kimura T, Takeuchi M, Hamachi I, Shinkai S. Sugar-Induced Chiral Orientation of Boronic-Acid-Appended Amphiphile Clusters Formed in the Dipalmitoylphosphatidylcholine (DPPC) Membrane Israel Journal of Chemistry. 36: 379-388. DOI: 10.1002/Ijch.199600052  0.308
1995 Hamachi I, Kimura O, Takeshita H, Shinkai S. Peroxidase Activity of Cytochrome c Generated by Phenylboronic Acid Modification Chemistry Letters. 24: 529-530. DOI: 10.1246/Cl.1995.529  0.304
1994 Hamachi I, Tajiri Y, Murakami H, Shinkai S. Sugar-facilitated Incorporation of a Heme Cofactor Bearing Phenylboronic Acid Groups into Apomyoglobin Chemistry Letters. 23: 575-578. DOI: 10.1246/Cl.1994.575  0.306
1994 Nagasaki T, Kimura O, Hamachi I, Shinkai S. Novel Chemical Modification of Myoglobin by an Alcohol-Responsive Phenylboronic Acid Function Chemistry Letters. 23: 1945-1948. DOI: 10.1246/Cl.1994.1945  0.308
1994 Hamachi I, Nomoto K, Tanaka S, Tajiri Y, Shinkai S. Self-sufficient Electron Injection from NADH to the Active Center of Flavin-Pendant Myoglobin Chemistry Letters. 23: 1139-1142. DOI: 10.1246/Cl.1994.1139  0.339
1994 Murakami H, Nagasaki T, Hamachi I, Shinkai S. Sugar sensing utilizing aggregation properties of boronic-acid-appended porphyrins and metalloporphyrins Journal of the Chemical Society-Perkin Transactions 1. 975-981. DOI: 10.1039/P29940000975  0.375
1994 Nagasaki T, Kimura O, Ukon M, Arimori S, Hamachi I, Shinkai S. Synthesis, metal-binding properties and polypeptide solubilization of ‘crowned’ arborols Journal of the Chemical Society-Perkin Transactions 1. 75-81. DOI: 10.1039/P19940000075  0.369
1993 Hamachi I, Tanaka S, Shinkai S. Reconstitution of Myoglobin with a Heme Cofactor Bearing a Ruthenium Tris(2,2′-bipyridine) Pendant Chemistry Letters. 22: 1417-1420. DOI: 10.1246/Cl.1993.1417  0.356
1993 Murakami H, Nagasaki T, Hamachi I, Shinkai S. Sugar sensing utilizing aggregation properties of a boronic-acid-appended porphyrin Tetrahedron Letters. 34: 6273-6276. DOI: 10.1016/S0040-4039(00)73730-0  0.329
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