Katsutomo Okamura - Publications

Affiliations: 
Temasek Life Sciences Laboratory Limited, Singapore, Singapore 

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ho WY, Chak LL, Hor JH, Liu F, Diaz-Garcia S, Chang JC, Sanford E, Rodriguez MJ, Alagappan D, Lim SM, Cho YL, Shimizu Y, Sun AX, Tyan SH, Koo E, ... ... Okamura K, et al. FUS-dependent microRNA deregulations identify TRIB2 as a druggable target for ALS motor neurons. Iscience. 26: 108152. PMID 37920668 DOI: 10.1016/j.isci.2023.108152  0.401
2023 Feng C, Torimaru K, Lim MYT, Chak LL, Shiimori M, Tsuji K, Tanaka T, Iida J, Okamura K. A novel eukaryotic RdRP-dependent small RNA pathway represses antiviral immunity by controlling an ERK pathway component in the black-legged tick. Plos One. 18: e0281195. PMID 36996253 DOI: 10.1371/journal.pone.0281195  0.387
2019 Ong AAL, Toh DK, Krishna MS, Patil KM, Okamura K, Chen G. Incorporating 2-thiouracil into short dsRNA-binding PNAs for enhanced recognition of A-U pairs and for targeting a microRNA hairpin precursor. Biochemistry. PMID 31318532 DOI: 10.1021/Acs.Biochem.9B00521  0.3
2019 Ong AAL, Toh DK, Patil KM, Meng Z, Yuan Z, Krishna MS, Devi G, Haruehanroengra P, Lu Y, Xia K, Okamura K, Sheng J, Chen G. General recognition of U-G, U-A, and C-G pairs by double-stranded RNA-binding PNAs (dbPNAs) incorporated with an artificial nucleobase. Biochemistry. PMID 30775913 DOI: 10.1021/Acs.Biochem.8B01313  0.345
2018 Goh E, Okamura K. Hidden sequence specificity in loading of single-stranded RNAs onto Drosophila Argonautes. Nucleic Acids Research. PMID 30590701 DOI: 10.1093/Nar/Gky1300  0.452
2018 Zhou L, Lim MY, Kaur P, Saj A, Bortolamiol-Becet D, Gopal V, Tolwinski N, Tucker-Kellogg G, Okamura K. Importance of miRNA stability and alternative primary miRNA isoforms in gene regulation during development. Elife. 7. PMID 30024380 DOI: 10.7554/Elife.38389  0.565
2018 Teo RYW, Anand A, Sridhar V, Okamura K, Kai T. Heterochromatin protein 1a functions for piRNA biogenesis predominantly from pericentric and telomeric regions in Drosophila. Nature Communications. 9: 1735. PMID 29728561 DOI: 10.1038/S41467-018-03908-3  0.363
2018 Goh E, Okamura K. Gateway to Understanding Argonaute Loading of Single-Stranded RNAs: Preparation of Deep Sequencing Libraries with In Vitro Loading Samples. Methods in Molecular Biology (Clifton, N.J.). 1680: 41-63. PMID 29030840 DOI: 10.1007/978-1-4939-7339-2_3  0.456
2018 Zhou L, Lim MYT, Kaur P, Saj A, Bortolamiol-Becet D, Gopal V, Tolwinski N, Tucker-Kellogg G, Okamura K. Author response: Importance of miRNA stability and alternative primary miRNA isoforms in gene regulation during Drosophila development Elife. DOI: 10.7554/Elife.38389.048  0.535
2017 Lim MYT, Okamura K. Switches in Dicer Activity During Oogenesis and Early Development. Results and Problems in Cell Differentiation. 63: 325-351. PMID 28779324 DOI: 10.1007/978-3-319-60855-6_14  0.571
2016 Lim MY, Ng AW, Chou Y, Lim TP, Simcox A, Tucker-Kellogg G, Okamura K. The Drosophila Dicer-1 Partner Loquacious Enhances miRNA Processing from Hairpins with Unstable Structures at the Dicing Site. Cell Reports. PMID 27184838 DOI: 10.1016/J.Celrep.2016.04.059  0.563
2015 Pek JW, Okamura K. Regulatory RNAs discovered in unexpected places. Wiley Interdisciplinary Reviews. Rna. 6: 671-86. PMID 26424536 DOI: 10.1002/Wrna.1309  0.457
2015 Bortolamiol-Becet D, Hu F, Jee D, Wen J, Okamura K, Lin CJ, Ameres SL, Lai EC. Selective Suppression of the Splicing-Mediated MicroRNA Pathway by the Terminal Uridyltransferase Tailor. Molecular Cell. PMID 26145174 DOI: 10.1016/J.Molcel.2015.05.034  0.688
2015 Chak LL, Mohammed J, Lai EC, Tucker-Kellogg G, Okamura K. A deeply conserved, noncanonical miRNA hosted by ribosomal DNA. Rna (New York, N.Y.). 21: 375-84. PMID 25605965 DOI: 10.1261/Rna.049098.114  0.691
2015 Wen J, Duan H, Bejarano F, Okamura K, Fabian L, Brill JA, Bortolamiol-Becet D, Martin R, Ruby JG, Lai EC. Adaptive regulation of testis gene expression and control of male fertility by the Drosophila harpin RNA pathway. Molecular Cell. 57: 165-78. PMID 25544562 DOI: 10.1016/J.Molcel.2014.11.025  0.611
2014 Hu F, Lai EC, Okamura K. A signaling-induced switch in dicer localization and function. Developmental Cell. 31: 523-4. PMID 25490263 DOI: 10.1016/J.Devcel.2014.11.032  0.504
2014 Wen J, Mohammed J, Bortolamiol-Becet D, Tsai H, Robine N, Westholm JO, Ladewig E, Dai Q, Okamura K, Flynt AS, Zhang D, Andrews J, Cherbas L, Kaufman TC, Cherbas P, et al. Diversity of miRNAs, siRNAs, and piRNAs across 25 Drosophila cell lines. Genome Research. 24: 1236-50. PMID 24985917 DOI: 10.1101/Gr.161554.113  0.763
2014 Chak LL, Okamura K. Argonaute-dependent small RNAs derived from single-stranded, non-structured precursors. Frontiers in Genetics. 5: 172. PMID 24959173 DOI: 10.3389/Fgene.2014.00172  0.51
2013 Okamura K. Argonaute reformatting. Molecular Cell. 50: 305-6. PMID 23664373 DOI: 10.1016/j.molcel.2013.04.019  0.397
2013 Okamura K, Ladewig E, Zhou L, Lai EC. Functional small RNAs are generated from select miRNA hairpin loops in flies and mammals. Genes & Development. 27: 778-92. PMID 23535236 DOI: 10.1101/Gad.211698.112  0.697
2012 Ladewig E, Okamura K, Flynt AS, Westholm JO, Lai EC. Discovery of hundreds of mirtrons in mouse and human small RNA data. Genome Research. 22: 1634-45. PMID 22955976 DOI: 10.1101/Gr.133553.111  0.785
2012 Westholm JO, Ladewig E, Okamura K, Robine N, Lai EC. Common and distinct patterns of terminal modifications to mirtrons and canonical microRNAs. Rna (New York, N.Y.). 18: 177-92. PMID 22190743 DOI: 10.1261/Rna.030627.111  0.77
2012 Okamura K. Diversity of animal small RNA pathways and their biological utility. Wiley Interdisciplinary Reviews. Rna. 3: 351-68. PMID 22086843 DOI: 10.1002/Wrna.113  0.606
2011 Berezikov E, Robine N, Samsonova A, Westholm JO, Naqvi A, Hung JH, Okamura K, Dai Q, Bortolamiol-Becet D, Martin R, Zhao Y, Zamore PD, Hannon GJ, Marra MA, Weng Z, et al. Deep annotation of Drosophila melanogaster microRNAs yields insights into their processing, modification, and emergence. Genome Research. 21: 203-15. PMID 21177969 DOI: 10.1101/Gr.116657.110  0.781
2011 Chung WJ, Agius P, Westholm JO, Chen M, Okamura K, Robine N, Leslie CS, Lai EC. Computational and experimental identification of mirtrons in Drosophila melanogaster and Caenorhabditis elegans. Genome Research. 21: 286-300. PMID 21177960 DOI: 10.1101/Gr.113050.110  0.764
2011 Okamura K, Robine N, Liu Y, Liu Q, Lai EC. R2D2 organizes small regulatory RNA pathways in Drosophila. Molecular and Cellular Biology. 31: 884-96. PMID 21135122 DOI: 10.1128/Mcb.01141-10  0.796
2010 Hain D, Bettencourt BR, Okamura K, Csorba T, Meyer W, Jin Z, Biggerstaff J, Siomi H, Hutvagner G, Lai EC, Welte M, Müller HA. Natural variation of the amino-terminal glutamine-rich domain in Drosophila argonaute2 is not associated with developmental defects. Plos One. 5: e15264. PMID 21253006 DOI: 10.1371/Journal.Pone.0015264  0.546
2010 Roy S, Ernst J, Kharchenko PV, Kheradpour P, Negre N, Eaton ML, Landolin JM, Bristow CA, Ma L, Lin MF, Washietl S, Arshinoff BI, Ay F, Meyer PE, ... ... Okamura K, et al. Identification of functional elements and regulatory circuits by Drosophila modENCODE. Science (New York, N.Y.). 330: 1787-97. PMID 21177974 DOI: 10.1126/Science.1198374  0.742
2010 Okamura K, Lai EC. A deathly DNase activity for dicer. Developmental Cell. 18: 692-4. PMID 20493803 DOI: 10.1016/J.Devcel.2010.05.004  0.436
2009 Robine N, Lau NC, Balla S, Jin Z, Okamura K, Kuramochi-Miyagawa S, Blower MD, Lai EC. A broadly conserved pathway generates 3'UTR-directed primary piRNAs. Current Biology : Cb. 19: 2066-76. PMID 20022248 DOI: 10.1016/J.Cub.2009.11.064  0.744
2009 Okamura K, Lai EC. [Diversity and complexity of dicer dependent small RNA networks in animals]. Seikagaku. the Journal of Japanese Biochemical Society. 81: 904-9. PMID 19928532  0.498
2009 Okamura K, Liu N, Lai EC. Distinct mechanisms for microRNA strand selection by Drosophila Argonautes. Molecular Cell. 36: 431-44. PMID 19917251 DOI: 10.1016/J.Molcel.2009.09.027  0.681
2008 Okamura K, Balla S, Martin R, Liu N, Lai EC. Two distinct mechanisms generate endogenous siRNAs from bidirectional transcription in Drosophila melanogaster. Nature Structural & Molecular Biology. 15: 998. PMID 18769470 DOI: 10.1038/nsmb0908-998c  0.453
2008 Okamura K, Chung WJ, Lai EC. The long and short of inverted repeat genes in animals: microRNAs, mirtrons and hairpin RNAs. Cell Cycle (Georgetown, Tex.). 7: 2840-5. PMID 18769156 DOI: 10.4161/Cc.7.18.6734  0.718
2008 Okamura K, Lai EC. Endogenous small interfering RNAs in animals. Nature Reviews. Molecular Cell Biology. 9: 673-8. PMID 18719707 DOI: 10.1038/Nrm2479  0.612
2008 Liu N, Okamura K, Tyler DM, Phillips MD, Chung WJ, Lai EC. The evolution and functional diversification of animal microRNA genes. Cell Research. 18: 985-96. PMID 18711447 DOI: 10.1038/Cr.2008.278  0.679
2008 Chung WJ, Okamura K, Martin R, Lai EC. Endogenous RNA interference provides a somatic defense against Drosophila transposons. Current Biology : Cb. 18: 795-802. PMID 18501606 DOI: 10.1016/J.Cub.2008.05.006  0.62
2008 Okamura K, Balla S, Martin R, Liu N, Lai EC. Two distinct mechanisms generate endogenous siRNAs from bidirectional transcription in Drosophila melanogaster. Nature Structural & Molecular Biology. 15: 581-90. PMID 18500351 DOI: 10.1038/Nsmb.1438  0.608
2008 Okamura K, Chung WJ, Ruby JG, Guo H, Bartel DP, Lai EC. The Drosophila hairpin RNA pathway generates endogenous short interfering RNAs. Nature. 453: 803-6. PMID 18463630 DOI: 10.1038/Nature07015  0.626
2008 Okamura K, Phillips MD, Tyler DM, Duan H, Chou YT, Lai EC. The regulatory activity of microRNA* species has substantial influence on microRNA and 3' UTR evolution. Nature Structural & Molecular Biology. 15: 354-63. PMID 18376413 DOI: 10.1038/Nsmb.1409  0.679
2008 Cayirlioglu P, Kadow IG, Zhan X, Okamura K, Suh GS, Gunning D, Lai EC, Zipursky SL. Hybrid neurons in a microRNA mutant are putative evolutionary intermediates in insect CO2 sensory systems. Science (New York, N.Y.). 319: 1256-60. PMID 18309086 DOI: 10.1126/Science.1149483  0.445
2008 Tyler DM, Okamura K, Chung WJ, Hagen JW, Berezikov E, Hannon GJ, Lai EC. Functionally distinct regulatory RNAs generated by bidirectional transcription and processing of microRNA loci. Genes & Development. 22: 26-36. PMID 18172163 DOI: 10.1101/Gad.1615208  0.659
2007 Silver SJ, Hagen JW, Okamura K, Perrimon N, Lai EC. Functional screening identifies miR-315 as a potent activator of Wingless signaling. Proceedings of the National Academy of Sciences of the United States of America. 104: 18151-6. PMID 17989227 DOI: 10.1073/Pnas.0706673104  0.625
2007 Okamura K, Hagen JW, Duan H, Tyler DM, Lai EC. The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila. Cell. 130: 89-100. PMID 17599402 DOI: 10.1016/J.Cell.2007.06.028  0.72
2004 Okamura K, Ishizuka A, Siomi H, Siomi MC. Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways. Genes & Development. 18: 1655-66. PMID 15231716 DOI: 10.1101/gad.1210204  0.348
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