| Year |
Citation |
Score |
| 2023 |
Pöysti S, Silojärvi S, Brodnicki TC, Catterall T, Liu X, Mackin L, Luster AD, Kay TWH, Christen U, Thomas HE, Hänninen A. Gut dysbiosis promotes islet-autoimmunity by increasing T-cell attraction in islets via CXCL10 chemokine. Journal of Autoimmunity. 140: 103090. PMID 37572540 DOI: 10.1016/j.jaut.2023.103090 |
0.439 |
|
| 2022 |
Tuovinen EA, Pöysti S, Hamdan F, Le KM, Keskitalo S, Turunen T, Minier L, Mamia N, Heiskanen K, Varjosalo M, Cerullo V, Kere J, Seppänen MRJ, Hänninen A, Grönholm J. Characterization of Expanded Gamma Delta T Cells from Atypical X-SCID Patient Reveals Preserved Function and IL2RG-Mediated Signaling. Journal of Clinical Immunology. PMID 36260239 DOI: 10.1007/s10875-022-01375-6 |
0.332 |
|
| 2022 |
Pöysti S, Toivonen R, Takeda A, Silojärvi S, Yatkin E, Miyasaka M, Hänninen A. Infection with the enteric pathogen C. rodentium promotes islet-specific autoimmunity by activating a lymphatic route from the gut to pancreatic lymph node. Mucosal Immunology. 15: 471-479. PMID 35140345 DOI: 10.1038/s41385-022-00490-2 |
0.63 |
|
| 2020 |
Pöysti S, Silojärvi S, Toivonen R, Hänninen A. Plasmacytoid dendritic cells regulate host immune response to Citrobacter rodentium -induced colitis in colon-draining lymph nodes. European Journal of Immunology. PMID 33078848 DOI: 10.1002/eji.202048714 |
0.334 |
|
| 2020 |
Tuovinen EA, Grönholm J, Öhman T, Pöysti S, Toivonen R, Kreutzman A, Heiskanen K, Trotta L, Toiviainen-Salo S, Routes JM, Verbsky J, Mustjoki S, Saarela J, Kere J, Varjosalo M, et al. Novel Hemizygous IL2RG p.(Pro58Ser) Mutation Impairs IL-2 Receptor Complex Expression on Lymphocytes Causing X-Linked Combined Immunodeficiency. Journal of Clinical Immunology. PMID 32072341 DOI: 10.1007/S10875-020-00745-2 |
0.331 |
|
| 2018 |
Keto J, Kaartinen T, Salmenniemi U, Castrén J, Partanen J, Hänninen A, Korhonen M, Lähteenmäki K, Itälä-Remes M, Nystedt J. Immunomonitoring of MSC-Treated GvHD Patients Reveals Only Moderate Potential for Response Prediction but Indicates Treatment Safety. Molecular Therapy. Methods & Clinical Development. 9: 109-118. PMID 29516024 DOI: 10.1016/J.Omtm.2018.02.001 |
0.39 |
|
| 2018 |
Ainola M, Porola P, Takakubo Y, Przybyla B, Kouri V, Tolvanen TA, Hänninen A, Nordström DC. Activation of plasmacytoid dendritic cells by apoptotic particles - mechanism for the loss of immunological tolerance in Sjögren's syndrome. Clinical and Experimental Immunology. 191: 301-310. PMID 29105068 DOI: 10.1111/Cei.13077 |
0.313 |
|
| 2017 |
Hänninen A, Toivonen R, Pöysti S, Belzer C, Plovier H, Ouwerkerk JP, Emani R, Cani PD, De Vos WM. Akkermansia muciniphila induces gut microbiota remodelling and controls islet autoimmunity in NOD mice. Gut. PMID 29269438 DOI: 10.1136/Gutjnl-2017-314508 |
0.353 |
|
| 2017 |
Hänninen A. Infections in MS: An innate immunity perspective. Acta Neurologica Scandinavica. 136: 10-14. PMID 29068495 DOI: 10.1111/Ane.12838 |
0.32 |
|
| 2017 |
Munukka E, Rintala A, Toivonen R, Nylund M, Yang B, Takanen A, Hänninen A, Vuopio J, Huovinen P, Jalkanen S, Pekkala S. Faecalibacterium prausnitzii treatment improves hepatic health and reduces adipose tissue inflammation in high-fat fed mice. The Isme Journal. PMID 28375212 DOI: 10.1038/Ismej.2017.24 |
0.497 |
|
| 2016 |
Toivonen R, Kong L, Rasool O, Lund RJ, Lahesmaa R, Hänninen A. Activation of Plasmacytoid Dendritic Cells in Colon-Draining Lymph Nodes during Citrobacter rodentium Infection Involves Pathogen-Sensing and Inflammatory Pathways Distinct from Conventional Dendritic Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 27183629 DOI: 10.4049/Jimmunol.1600235 |
0.371 |
|
| 2016 |
Ainola M, Porola P, Takakubo Y, Przybyla B, Tolvanen T, Hänninen A, Konttinen Y, Nordström D. THU0270 Activation of Plasmacytoid Dendritic Cells by Apoptotic Particles - Mechanism for The Loss of Immunologic Tolerance in Androgen-Depleted Sjögren's Syndrome Annals of the Rheumatic Diseases. 75: 285-285. DOI: 10.1136/Annrheumdis-2016-Eular.4190 |
0.303 |
|
| 2015 |
Toivonen R, Arstila TP, Hänninen A. Islet-associated T-cell receptor-β CDR sequence repertoire in prediabetic NOD mice reveals antigen-driven T-cell expansion and shared usage of VβJβ TCR chains Molecular Immunology. 64: 127-135. PMID 25480393 DOI: 10.1016/J.Molimm.2014.11.009 |
0.483 |
|
| 2015 |
Emani R, Alam C, Pekkala S, Zafar S, Emani MR, Hänninen A. Peritoneal cavity is a route for gut-derived microbial signals to promote autoimmunity in non-obese diabetic mice. Scandinavian Journal of Immunology. 81: 102-9. PMID 25410403 DOI: 10.1111/Sji.12253 |
0.485 |
|
| 2015 |
Haapaniemi EM, Kaustio M, Rajala HL, van Adrichem AJ, Kainulainen L, Glumoff V, Doffinger R, Kuusanmäki H, Heiskanen-Kosma T, Trotta L, Chiang S, Kulmala P, Eldfors S, Katainen R, Siitonen S, et al. Autoimmunity, hypogammaglobulinemia, lymphoproliferation, and mycobacterial disease in patients with activating mutations in STAT3. Blood. 125: 639-48. PMID 25349174 DOI: 10.1182/Blood-2014-04-570101 |
0.385 |
|
| 2014 |
Toivonen RK, Emani R, Munukka E, Rintala A, Laiho A, Pietilä S, Pursiheimo JP, Soidinsalo P, Linhala M, Eerola E, Huovinen P, Hänninen A. Fermentable fibres condition colon microbiota and promote diabetogenesis in NOD mice. Diabetologia. 57: 2183-92. PMID 25031069 DOI: 10.1007/S00125-014-3325-6 |
0.323 |
|
| 2014 |
Asghar MN, Emani R, Alam C, Helenius TO, Grönroos TJ, Sareila O, Din MU, Holmdahl R, Hänninen A, Toivola DM. In vivo imaging of reactive oxygen and nitrogen species in murine colitis Inflammatory Bowel Diseases. 20: 1435-1447. PMID 24983980 DOI: 10.1097/Mib.0000000000000118 |
0.326 |
|
| 2013 |
Alam CM, Silvander JS, Daniel EN, Tao GZ, Kvarnström SM, Alam P, Omary MB, Hänninen A, Toivola DM. Keratin 8 modulates β-cell stress responses and normoglycaemia. Journal of Cell Science. 126: 5635-44. PMID 24144696 DOI: 10.1242/Jcs.132795 |
0.359 |
|
| 2013 |
Emani R, Asghar MN, Toivonen R, Lauren L, Söderström M, Toivola DM, van Tol EA, Hänninen A. Casein hydrolysate diet controls intestinal T cell activation, free radical production and microbial colonisation in NOD mice. Diabetologia. 56: 1781-91. PMID 23748859 DOI: 10.1007/S00125-013-2941-X |
0.419 |
|
| 2011 |
Alam C, Bittoun E, Bhagwat D, Valkonen S, Saari A, Jaakkola U, Eerola E, Huovinen P, Hänninen A. Effects of a germ-free environment on gut immune regulation and diabetes progression in non-obese diabetic (NOD) mice. Diabetologia. 54: 1398-406. PMID 21380595 DOI: 10.1007/S00125-011-2097-5 |
0.398 |
|
| 2011 |
Hänninen A, Maksimow M, Alam C, Morgan DJ, Jalkanen S. Ly6C supports preferential homing of central memory CD8+ T cells into lymph nodes. European Journal of Immunology. 41: 634-44. PMID 21308682 DOI: 10.1002/Eji.201040760 |
0.596 |
|
| 2010 |
Kekäläinen E, Hänninen A, Maksimow M, Arstila TP. T cells expressing two different T cell receptors form a heterogeneous population containing autoreactive clones. Molecular Immunology. 48: 211-8. PMID 20828824 DOI: 10.1016/J.Molimm.2010.08.008 |
0.45 |
|
| 2010 |
Sia C, Hänninen A. Functional alterations of proinflammatory monocytes by T regulatory cells: implications for the prevention and reversal of type 1 diabetes. The Review of Diabetic Studies : Rds. 7: 6-14. PMID 20703434 DOI: 10.1900/RDS.2010.7.6 |
0.372 |
|
| 2010 |
Alam C, Valkonen S, Palagani V, Jalava J, Eerola E, Hänninen A. Inflammatory tendencies and overproduction of IL-17 in the colon of young NOD mice are counteracted with diet change. Diabetes. 59: 2237-46. PMID 20547977 DOI: 10.2337/Db10-0147 |
0.357 |
|
| 2010 |
Hänninen A, Soilu-Hänninen M, Hampe CS, Deptula A, Geubtner K, Ilonen J, Knip M, Reijonen H. Characterization of CD4+ T cells specific for glutamic acid decarboxylase (GAD65) and proinsulin in a patient with stiff-person syndrome but without type 1 diabetes. Diabetes/Metabolism Research and Reviews. 26: 271-9. PMID 20503259 DOI: 10.1002/Dmrr.1083 |
0.319 |
|
| 2010 |
Alam C, Valkonen S, Ohls S, Törnqvist K, Hänninen A. Enhanced trafficking to the pancreatic lymph nodes and auto-antigen presentation capacity distinguishes peritoneal B lymphocytes in non-obese diabetic mice Diabetologia. 53: 346-355. PMID 20033667 DOI: 10.1007/S00125-009-1599-X |
0.47 |
|
| 2008 |
Maksimow M, Alam C, Hänninen A. Incomplete Killing And Enhanced Activation of Islet-Reactive CD8+ T Cells by FasL-Expressing Dendritic Cells Limits Protection from Diabetes. The Review of Diabetic Studies : Rds. 5: 144-53. PMID 19099086 DOI: 10.1900/RDS.2008.5.144 |
0.388 |
|
| 2007 |
Koskinen K, Nevalainen S, Karikoski M, Hänninen A, Jalkanen S, Salmi M. VAP-1-deficient mice display defects in mucosal immunity and antimicrobial responses: implications for antiadhesive applications. Journal of Immunology (Baltimore, Md. : 1950). 179: 6160-8. PMID 17947691 DOI: 10.4049/Jimmunol.179.9.6160 |
0.676 |
|
| 2007 |
Hänninen A, Nurmela R, Maksimow M, Heino J, Jalkanen S, Kurts C. Islet beta-cell-specific T cells can use different homing mechanisms to infiltrate and destroy pancreatic islets. The American Journal of Pathology. 170: 240-50. PMID 17200197 DOI: 10.2353/Ajpath.2007.060142 |
0.629 |
|
| 2006 |
Maksimow M, Miiluniemi M, Marttila-Ichihara F, Jalkanen S, Hänninen A. Antigen targeting to endosomal pathway in dendritic cell vaccination activates regulatory T cells and attenuates tumor immunity. Blood. 108: 1298-305. PMID 16621963 DOI: 10.1182/Blood-2005-11-008615 |
0.58 |
|
| 2006 |
Maksimow M, Söderström TS, Jalkanen S, Eriksson JE, Hänninen A. Fas costimulation of naive CD4 T cells is controlled by NF-kappaB signaling and caspase activity. Journal of Leukocyte Biology. 79: 369-77. PMID 16330535 DOI: 10.1189/Jlb.0505238 |
0.561 |
|
| 2005 |
Soilu-Hänninen M, Laaksonen M, Hänninen A, Erälinna JP, Panelius M. Downregulation of VLA-4 on T cells as a marker of long term treatment response to interferon beta-1a in MS. Journal of Neuroimmunology. 167: 175-82. PMID 16087245 DOI: 10.1016/J.Jneuroim.2005.06.022 |
0.343 |
|
| 2005 |
Soilu-Hänninen M, Laaksonen M, Hänninen A. Hyaluronate receptor (CD44) and integrin alpha4 (CD49d) are up-regulated on T cells during MS relapses. Journal of Neuroimmunology. 166: 189-92. PMID 15990174 DOI: 10.1016/J.Jneuroim.2005.05.008 |
0.38 |
|
| 2005 |
Merinen M, Irjala H, Salmi M, Jaakkola I, Hänninen A, Jalkanen S. Vascular adhesion protein-1 is involved in both acute and chronic inflammation in the mouse. The American Journal of Pathology. 166: 793-800. PMID 15743791 DOI: 10.1016/S0002-9440(10)62300-0 |
0.648 |
|
| 2005 |
Stolen CM, Marttila-Ichihara F, Koskinen K, Yegutkin GG, Turja R, Bono P, Skurnik M, Hänninen A, Jalkanen S, Salmi M. Absence of the endothelial oxidase AOC3 leads to abnormal leukocyte traffic in vivo. Immunity. 22: 105-15. PMID 15664163 DOI: 10.1016/J.Immuni.2004.12.006 |
0.717 |
|
| 2003 |
Hänninen A, Hamilton-Williams E, Kurts C. Development of new strategies to prevent type 1 diabetes: the role of animal models. Annals of Medicine. 35: 546-63. PMID 14708966 DOI: 10.1080/07853890310014597 |
0.427 |
|
| 2003 |
Jaakkola I, Jalkanen S, Hänninen A. Diabetogenic T cells are primed both in pancreatic and gut-associated lymph nodes in NOD mice. European Journal of Immunology. 33: 3255-64. PMID 14635033 DOI: 10.1002/Eji.200324405 |
0.588 |
|
| 2003 |
Jaakkola I, Merinen M, Jalkanen S, Hänninen A. Ly6C induces clustering of LFA-1 (CD11a/CD18) and is involved in subtype-specific adhesion of CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 170: 1283-90. PMID 12538687 DOI: 10.4049/Jimmunol.170.3.1283 |
0.594 |
|
| 2003 |
Maksimow M, Santanen M, Jalkanen S, Hänninen A. Responding naive T cells differ in their sensitivity to Fas engagement: early death of many T cells is compensated by costimulation of surviving T cells. Blood. 101: 4022-8. PMID 12531803 DOI: 10.1182/Blood-2002-06-1904 |
0.597 |
|
| 2002 |
Hänninen A, Martinez NR, Davey GM, Heath WR, Harrison LC. Transient blockade of CD40 ligand dissociates pathogenic from protective mucosal immunity Journal of Clinical Investigation. 109: 261-267. PMID 11805138 DOI: 10.1172/Jci13720 |
0.354 |
|
| 1997 |
Hänninen A, Jaakkola I, Salmi M, Simell O, Jalkanen S. Ly-6C regulates endothelial adhesion and homing of CD8(+) T cells by activating integrin-dependent adhesion pathways. Proceedings of the National Academy of Sciences of the United States of America. 94: 6898-903. PMID 9192663 DOI: 10.1073/Pnas.94.13.6898 |
0.675 |
|
| 1996 |
Soilu-Hänninen M, Hänninen A, Ilonen J, Salmi A, Salonen R. Measles virus hemagglutinin mediates monocyte aggregation and increased adherence to measles-infected endothelial cells Medical Microbiology and Immunology. 185: 73-80. PMID 8884738 DOI: 10.1007/S004300050017 |
0.379 |
|
| 1996 |
Hänninen A, Salmi M, Simell O, Jalkanen S. Mucosa-associated (beta 7-integrinhigh) lymphocytes accumulate early in the pancreas of NOD mice and show aberrant recirculation behavior. Diabetes. 45: 1173-80. PMID 8772718 DOI: 10.2337/Diab.45.9.1173 |
0.679 |
|
| 1996 |
Hanninen A, Salmi M, Simell O, Andrew D, Jalkanen S. Recirculation and homing of lymphocyte subsets: dual homing specificity of beta 7-integrin(high)-lymphocytes in nonobese diabetic mice Blood. 88: 934-944. DOI: 10.1182/Blood.V88.3.934.Bloodjournal883934 |
0.658 |
|
| 1993 |
Hänninen A, Salmi M, Simell O, Jalkanen S. Endothelial cell-binding properties of lymphocytes infiltrated into human diabetic pancreas. Implications for pathogenesis of IDDM. Diabetes. 42: 1656-62. PMID 8405709 DOI: 10.2337/Diab.42.11.1656 |
0.699 |
|
| 1992 |
Hänninen A, Jalkanen S, Salmi M, Toikkanen S, Nikolakaros G, Simell O. Macrophages, T cell receptor usage, and endothelial cell activation in the pancreas at the onset of insulin-dependent diabetes mellitus. The Journal of Clinical Investigation. 90: 1901-10. PMID 1385478 DOI: 10.1172/Jci116067 |
0.698 |
|
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