C. Michael Stein, M.B.Ch.B. - Publications

Affiliations: 
Department of Medicine, Division of Rheumatology & Immunology Vanderbilt University School of Medicine, Nashville, TN, United States 
Website:
https://medsites.mc.vanderbilt.edu/steinlab/home

102 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Jiang L, Gangireddy S, Dickson AL, Kawai V, Cox NJ, Linton MF, Wei WQ, Stein CM, Feng Q. Characterizing genetic profiles for high triglyceride levels in U.S. patients of African ancestry. Medrxiv : the Preprint Server For Health Sciences. PMID 38559137 DOI: 10.1101/2024.03.11.24304107  0.607
2023 Yan C, Ong HH, Grabowska ME, Krantz MS, Su WC, Dickson AL, Peterson JF, Feng Q, Roden DM, Stein CM, Kerchberger VE, Malin BA, Wei WQ. Large Language Models Facilitate the Generation of Electronic Health Record Phenotyping Algorithms. Medrxiv : the Preprint Server For Health Sciences. PMID 38196578 DOI: 10.1101/2023.12.19.23300230  0.521
2023 Jiang L, Liu G, Oeser A, Ihegword A, Dickson AL, Daniel LL, Hung AM, Cox NJ, Chung CP, Wei WQ, Stein CM, Feng Q. Association between risk variants and the occurrence of sepsis in Black patients hospitalized with infections: a retrospective cohort study. Elife. 12. PMID 37882666 DOI: 10.7554/eLife.88538  0.601
2023 Zanussi JT, Zhao J, Wei WQ, Karakoc G, Chung CP, Feng Q, Olsen NJ, Stein CM, Kawai VK. Clinical diagnoses associated with a positive antinuclear antibody test in patients with and without autoimmune disease. Bmc Rheumatology. 7: 24. PMID 37550754 DOI: 10.1186/s41927-023-00349-4  0.547
2023 Yan C, Grabowska ME, Dickson AL, Li B, Wen Z, Roden DM, Stein CM, Embí PJ, Peterson JF, Feng Q, Malin BA, Wei WQ. Leveraging Generative AI to Prioritize Drug Repurposing Candidates: Validating Identified Candidates for Alzheimer's Disease in Real-World Clinical Datasets. Medrxiv : the Preprint Server For Health Sciences. PMID 37461512 DOI: 10.1101/2023.07.07.23292388  0.577
2023 Jiang L, Liu G, Oeser A, Ihegword A, Dickson AL, Daniel LL, Hung AM, Cox NJ, Chung CP, Wei WQ, Stein CM, Feng Q. Association between risk variants and progression from infection to sepsis. Medrxiv : the Preprint Server For Health Sciences. PMID 36747677 DOI: 10.1101/2023.01.27.23284540  0.604
2023 Davis A, Dickson AL, Daniel LL, Nepal P, Zanussi J, Miller-Fleming TW, Straub PS, Wei WQ, Liu G, Cox NJ, Hung AM, Feng Q, Stein CM, Chung CP. Association Between Genetically Predicted Expression of TPMT and Azathioprine Adverse Events. Research Square. PMID 36711487 DOI: 10.21203/rs.3.rs-2444787/v1  0.61
2023 Liu G, Jiang L, Kerchberger VE, Oeser A, Ihegword A, Dickson AL, Daniel LL, Shaffer C, Linton MF, Cox N, Chung CP, Wei WQ, Stein CM, Feng Q. The relationship between high density lipoprotein cholesterol and sepsis: A clinical and genetic approach. Clinical and Translational Science. PMID 36645160 DOI: 10.1111/cts.13462  0.589
2022 Jiang L, Kerchberger VE, Shaffer C, Dickson AL, Ormseth MJ, Daniel LL, Leon BGC, Cox NJ, Chung CP, Wei WQ, Stein CM, Feng Q. Genome-wide association analyses of common infections in a large practice-based biobank. Bmc Genomics. 23: 672. PMID 36167494 DOI: 10.1186/s12864-022-08888-9  0.553
2022 Akwo EA, Chen HC, Liu G, Triozzi JL, Tao R, Yu Z, Chung CP, Giri A, Ikizler TA, Stein CM, Siew ED, Feng Q, Robinson-Cohen C, Hung AM. Phenome-Wide Association Study of Gene Variants and Differential Associations With Clinical Outcomes Across Populations in the Million Veteran Program a Multiethnic Biobank. Kidney International Reports. 7: 1802-1818. PMID 35967117 DOI: 10.1016/j.ekir.2022.05.011  0.573
2022 Dickson AL, Daniel LL, Jackson E, Zanussi J, Yang W, Plummer WD, Dupont WD, Wei WQ, Nepal P, Hung AM, Cox NJ, Van Driest SL, Feng Q, Yang JJ, Stein CM, et al. Race, Genotype, and Azathioprine Discontinuation : A Cohort Study. Annals of Internal Medicine. PMID 35724382 DOI: 10.7326/M21-4675  0.585
2022 Daniel LL, Dickson AL, Zanussi JT, Miller-Fleming TW, Straub PS, Wei WQ, Plummer WD, Dupont WD, Liu G, Anandi P, Reese TS, Birdwell KA, Kawai VK, Hung AM, Cox NJ, ... ... Stein CM, et al. Predicted expression of genes involved in the thiopurine metabolic pathway and azathioprine discontinuation due to myelotoxicity. Clinical and Translational Science. PMID 35118815 DOI: 10.1111/cts.13243  0.599
2022 Wu P, Feng Q, Kerchberger VE, Nelson SD, Chen Q, Li B, Edwards TL, Cox NJ, Phillips EJ, Stein CM, Roden DM, Denny JC, Wei WQ. Integrating gene expression and clinical data to identify drug repurposing candidates for hyperlipidemia and hypertension. Nature Communications. 13: 46. PMID 35013250 DOI: 10.1038/s41467-021-27751-1  0.742
2021 Zanussi JT, Zhao J, Dorn CA, Liu G, Feng Q, Wei W, Mosley JD, Stein CM, Kawai VK. Identifying potential therapeutic applications and diagnostic harms of increased bilirubin concentrations - a clinical and genetic approach. Clinical Pharmacology and Therapeutics. PMID 34625956 DOI: 10.1002/cpt.2441  0.613
2021 Dickson AL, Daniel LL, Zanussi J, Plummer WD, Wei WQ, Liu G, Reese T, Anandi P, Birdwell KA, Kawai V, Cox NJ, Dupont WD, Hung AM, Feng Q, Stein CM, et al. TPMT and NUDT15 Variants Predict Discontinuation of Azathioprine for Myelotoxicity in Patients with Inflammatory Disease: Real-World Clinical Results. Clinical Pharmacology and Therapeutics. PMID 34582038 DOI: 10.1002/cpt.2428  0.608
2021 Liu G, Shi M, Mosley JD, Weng C, Zhang Y, Lee MTM, Jarvik GP, Hakonarson H, Namjou-Khales B, Sleiman P, Luo Y, Mentch F, Denny JC, Linton MF, Wei WQ, ... Stein CM, et al. A Mendelian Randomization Approach Using 3-HMG-Coenzyme-A Reductase Gene Variation to Evaluate the Association of Statin-Induced Low-Density Lipoprotein Cholesterol Lowering With Noncardiovascular Disease Phenotypes. Jama Network Open. 4: e2112820. PMID 34097045 DOI: 10.1001/jamanetworkopen.2021.12820  0.582
2021 Zheng NS, Stone CA, Jiang L, Shaffer CM, Kerchberger VE, Chung CP, Feng Q, Cox NJ, Stein CM, Roden DM, Denny JC, Phillips EJ, Wei WQ. High-throughput framework for genetic analyses of adverse drug reactions using electronic health records. Plos Genetics. 17: e1009593. PMID 34061827 DOI: 10.1371/journal.pgen.1009593  0.605
2021 Kawai VK, Shi M, Liu G, Feng Q, Wei W, Chung CP, Walunas TL, Gordon AS, Linneman JG, Hebbring SJ, Harley JB, Cox NJ, Roden DM, Stein CM, Mosley JD. Pleiotropy of systemic lupus erythematosus risk alleles and cardiometabolic disorders: A phenome-wide association study and inverse-variance weighted meta-analysis. Lupus. 9612033211014952. PMID 33977795 DOI: 10.1177/09612033211014952  0.571
2021 Wu P, Nelson SD, Zhao J, Stone CA, Feng Q, Chen Q, Larson EA, Li B, Cox NJ, Stein CM, Phillips EJ, Roden DM, Denny JC, Wei WQ. DDIWAS: High-throughput electronic health record-based screening of drug-drug interactions. Journal of the American Medical Informatics Association : Jamia. PMID 33712848 DOI: 10.1093/jamia/ocab019  0.729
2020 Zheng NS, Feng Q, Kerchberger VE, Zhao J, Edwards TL, Cox NJ, Stein CM, Roden DM, Denny JC, Wei WQ. PheMap: a multi-resource knowledge base for high-throughput phenotyping within electronic health records. Journal of the American Medical Informatics Association : Jamia. PMID 32974638 DOI: 10.1093/jamia/ocaa104  0.527
2020 Mitchell SL, Leon DAC, Chaugai S, Kawai VK, Levinson RT, Wei WQ, Stein CM. Pharmacogenetics of hypoglycemia associated with sulfonylurea therapy in usual clinical care. The Pharmacogenomics Journal. PMID 32504053 DOI: 10.1038/S41397-020-0171-4  0.373
2020 Dikilitas O, Schaid DJ, Kosel ML, Carroll RJ, Chute CG, Denny JA, Fedotov A, Feng Q, Hakonarson H, Jarvik GP, Lee MTM, Pacheco JA, Rowley R, Sleiman PM, Stein CM, et al. Predictive Utility of Polygenic Risk Scores for Coronary Heart Disease in Three Major Racial and Ethnic Groups. American Journal of Human Genetics. 106: 707-716. PMID 32386537 DOI: 10.1016/J.Ajhg.2020.04.002  0.632
2020 Ahlers MJ, Lowery BD, Farber-Eger E, Wang TJ, Bradham W, Ormseth MJ, Chung CP, Stein CM, Gupta DK. Heart Failure Risk Associated With Rheumatoid Arthritis-Related Chronic Inflammation. Journal of the American Heart Association. e014661. PMID 32378457 DOI: 10.1161/Jaha.119.014661  0.352
2020 Kawai VK, Shi M, Feng Q, Chung CP, Liu G, Cox NJ, Jarvik GP, Lee MTM, Hebbring SJ, Harley JB, Kaufman KM, Namjou B, Larson E, Gordon AS, Roden DM, ... Stein CM, et al. Pleiotropy in the Genetic Predisposition to Rheumatoid Arthritis - a phenome-wide association study and inverse-variance weighted meta-analysis. Arthritis & Rheumatology (Hoboken, N.J.). PMID 32307929 DOI: 10.1002/Art.41291  0.615
2020 Bajaj A, Ihegword A, Qiu C, Small AM, Wei WQ, Bastarache L, Feng Q, Kember RL, Risman M, Bloom RD, Birtwell DL, Williams H, Shaffer CM, Chen J, Center RG, ... ... Stein CM, et al. Phenome-wide association analysis suggests the APOL1 linked disease spectrum primarily drives kidney-specific pathways. Kidney International. PMID 32247630 DOI: 10.1016/J.Kint.2020.01.027  0.634
2020 Anandi P, Dickson AL, Feng Q, Wei WQ, Dupont WD, Plummer D, Liu G, Octaria R, Barker KA, Kawai VK, Birdwell K, Cox NJ, Hung A, Stein CM, Chung CP. Combining clinical and candidate gene data into a risk score for azathioprine-associated leukopenia in routine clinical practice. The Pharmacogenomics Journal. PMID 32054992 DOI: 10.1038/S41397-020-0163-4  0.631
2019 Smit RAJ, Trompet S, Leong A, Goodarzi MO, Postmus I, Warren H, Theusch E, Barnes MR, Arsenault BJ, Li X, Feng Q, Chasman DI, Cupples LA, Hitman GA, Krauss RM, ... ... Stein CM, et al. Statin-induced LDL cholesterol response and type 2 diabetes: a bidirectional two-sample Mendelian randomization study. The Pharmacogenomics Journal. PMID 31801993 DOI: 10.1038/S41397-019-0125-X  0.619
2019 Feng Q, Wei WQ, Chaugai S, Carranza Leon BG, Kawai V, Carranza Leon DA, Jiang L, Zhong X, Liu G, Ihegword A, Shaffer CM, Linton MF, Chung CP, Stein CM. A Genetic Approach to the Association Between PCSK9 and Sepsis. Jama Network Open. 2: e1911130. PMID 31509211 DOI: 10.1001/jamanetworkopen.2019.11130  0.572
2019 Kawai VK, Nwosu SK, Kurnik D, Harrell FE, Stein CM. Variants in BMI-Associated Genes and Adrenergic Genes are not Associated with Gestational Weight Trajectory. Obesity (Silver Spring, Md.). PMID 31116007 DOI: 10.1002/Oby.22505  0.302
2019 Giles JT, Wasko MCM, Chung CP, Szklo M, Blumenthal RS, Kao A, Bokhari S, Zartoshti A, Stein CM, Bathon JM. Exploring the Lipid Paradox Theory in Rheumatoid Arthritis: Associations of Low Circulating Low Density Lipoprotein Concentration with Subclinical Coronary Atherosclerosis. Arthritis & Rheumatology (Hoboken, N.J.). PMID 30883031 DOI: 10.1002/Art.40889  0.324
2019 Safarova MS, Satterfield BA, Fan X, Austin EE, Ye Z, Bastarache L, Zheng N, Ritchie MD, Borthwick KM, Williams MS, Larson EB, Scrol A, Jarvik GP, Crosslin DR, Leppig K, ... ... Stein CM, et al. A phenome-wide association study to discover pleiotropic effects of , , and . Npj Genomic Medicine. 4: 3. PMID 30774981 DOI: 10.1038/S41525-019-0078-7  0.643
2019 Feng Q, Wei WQ, Chaugai S, Leon BGC, Mosley JD, Leon DAC, Jiang L, Ihegword A, Shaffer CM, Linton MF, Chung CP, Stein CM. Association Between Low-Density Lipoprotein Cholesterol Levels and Risk for Sepsis Among Patients Admitted to the Hospital With Infection. Jama Network Open. 2: e187223. PMID 30657536 DOI: 10.1001/jamanetworkopen.2018.7223  0.57
2018 Chaugai S, Dickson AL, Shuey MM, Feng Q, Barker KA, Wei WQ, Luther JM, Stein CM, Chung CP. Co-prescription of Strong CYP1A2 Inhibitors and the Risk of Tizanidine-Associated Hypotension: A Retrospective Cohort Study. Clinical Pharmacology and Therapeutics. PMID 30223305 DOI: 10.1002/Cpt.1233  0.625
2018 Mosley JD, Feng Q, Wells QS, Van Driest SL, Shaffer CM, Edwards TL, Bastarache L, Wei WQ, Davis LK, McCarty CA, Thompson W, Chute CG, Jarvik GP, Gordon AS, Palmer MR, ... ... Stein CM, et al. A study paradigm integrating prospective epidemiologic cohorts and electronic health records to identify disease biomarkers. Nature Communications. 9: 3522. PMID 30166544 DOI: 10.1038/S41467-018-05624-4  0.632
2018 Feng Q, Wei WQ, Chung CP, Levinson RT, Sundermann AC, Mosley JD, Bastarache L, Ferguson JF, Cox NJ, Roden DM, Denny JC, Linton MF, Edwards DRV, Stein CM. Relationship between very low low-density lipoprotein cholesterol concentrations not due to statin therapy and risk of type 2 diabetes: A US-based cross-sectional observational study using electronic health records. Plos Medicine. 15: e1002642. PMID 30153257 DOI: 10.1371/Journal.Pmed.1002642  0.613
2018 Byram KW, Oeser AM, Linton MF, Fazio S, Stein CM, Ormseth MJ. Exercise is Associated With Increased Small HDL Particle Concentration and Decreased Vascular Stiffness in Rheumatoid Arthritis. Journal of Clinical Rheumatology : Practical Reports On Rheumatic & Musculoskeletal Diseases. PMID 29846271 DOI: 10.1097/Rhu.0000000000000809  0.305
2018 Wei WQ, Li X, Feng Q, Kubo M, Kullo IJ, Peissig PL, Karlson EW, Jarvik GP, Lee MTM, Shang N, Larson EA, Edwards T, Shaffer C, Mosley JD, Maeda S, ... ... Stein CM, et al. Variants are Associated with Residual Cardiovascular Risk in Patients Receiving Statins. Circulation. PMID 29703846 DOI: 10.1161/Circulationaha.117.031356  0.639
2018 Phillips EJ, Wei W, Shaffer CM, Feng Q, Stone CA, Stein CM, Roden DM, Denny JC. A High-Throughput Genetic Analysis of Common Drug Allergy Labels Using Data from a Large Biobank Journal of Allergy and Clinical Immunology. 141: AB399. DOI: 10.1016/J.Jaci.2017.12.937  0.606
2017 Feng Q, Wei WQ, Levinson RT, Mosley JD, Stein CM. Replication and fine-mapping of genetic predictors of lipid traits in African-Americans. Journal of Human Genetics. PMID 28539666 DOI: 10.1038/Jhg.2017.55  0.625
2016 Ormseth MJ, Yancey PG, Yamamoto S, Oeser AM, Gebretsadik T, Shintani A, Linton MF, Fazio S, Davies SS, Roberts LJ, Vickers KC, Raggi P, Kon V, Stein CM. Net cholesterol efflux capacity of HDL enriched serum and coronary atherosclerosis in rheumatoid arthritis. Ijc Metabolic & Endocrine. 13: 6-11. PMID 28243578 DOI: 10.1016/J.Ijcme.2016.08.002  0.323
2016 Ferraz-Amaro I, Winchester R, Gregersen PK, Reynolds RJ, Wasko MC, Oeser A, Chung CP, Stein CM, Giles JT, Bathon JM. Coronary Artery Calcification and Rheumatoid Arthritis: Lack of Relationship to Risk Alleles for Coronary Artery Disease in the General Population. Arthritis & Rheumatology (Hoboken, N.J.). PMID 27696788 DOI: 10.1002/Art.39862  0.313
2016 Ray WA, Chung CP, Murray KT, Smalley WE, Daugherty JR, Dupont WD, Stein CM. Association of Proton Pump Inhibitors with Reduced Risk of Warfarin-related Serious Upper Gastrointestinal Bleeding. Gastroenterology. PMID 27639805 DOI: 10.1053/J.Gastro.2016.08.054  0.332
2016 Postmus I, Warren HR, Trompet S, Arsenault BJ, Avery CL, Bis JC, Chasman DI, de Keyser CE, Deshmukh HA, Evans DS, Feng Q, Li X, Smit RA, Smith AV, Sun F, ... ... Stein CM, et al. Meta-analysis of genome-wide association studies of HDL cholesterol response to statins. Journal of Medical Genetics. PMID 27587472 DOI: 10.1136/Jmedgenet-2016-103966  0.557
2016 Mosley JD, Witte JS, Larkin EK, Bastarache L, Shaffer CM, Karnes JH, Stein CM, Phillips E, Hebbring SJ, Brilliant MH, Mayer J, Ye Z, Roden DM, Denny JC. Identifying genetically driven clinical phenotypes using linear mixed models. Nature Communications. 7: 11433. PMID 27109359 DOI: 10.1038/Ncomms11433  0.341
2016 Ormseth MJ, Yancey PG, Solus JF, Bridges SL, Curtis JR, Linton MF, Fazio S, Davies SS, Roberts LJ, Vickers KC, Kon V, Stein CM. Effect of drug therapy on net cholesterol efflux capacity of HDL-enriched serum in rheumatoid arthritis. Arthritis & Rheumatology (Hoboken, N.J.). PMID 26991245 DOI: 10.1002/Art.39675  0.333
2015 Kohli U, Diedrich A, Kannankeril PJ, Muszkat M, Sofowora GG, Hahn MK, English BA, Blakely RD, Stein CM, Kurnik D. Genetic Variation in Alpha2-Adrenoreceptors and Heart Rate Recovery after Exercise. Physiological Genomics. physiolgenomics.0012. PMID 26058836 DOI: 10.1152/Physiolgenomics.00124.2014  0.311
2015 Chung CP, Solus JF, Oeser A, Li C, Raggi P, Smith JR, Stein CM. A variant in the osteoprotegerin gene is associated with coronary atherosclerosis in patients with rheumatoid arthritis: results from a candidate gene study. International Journal of Molecular Sciences. 16: 3885-94. PMID 25679449 DOI: 10.3390/Ijms16023885  0.334
2015 Solus JF, Chung CP, Oeser A, Li C, Rho YH, Bradley KM, Kawai VK, Smith JR, Stein CM. Genetics of serum concentration of IL-6 and TNFα in systemic lupus erythematosus and rheumatoid arthritis: a candidate gene analysis. Clinical Rheumatology. PMID 25652333 DOI: 10.1007/S10067-015-2881-6  0.321
2015 Kolek MJ, Muehlschlegel JD, Bush WS, Parvez B, Murray KT, Stein CM, Shoemaker MB, Blair MA, Kor KC, Roden DM, Donahue BS, Fox AA, Shernan SK, Collard CD, Body SC, et al. Genetic and clinical risk prediction model for postoperative atrial fibrillation. Circulation. Arrhythmia and Electrophysiology. 8: 25-31. PMID 25567478 DOI: 10.1161/Circep.114.002300  0.307
2015 Kawai VK, Chung CP, Solus JF, Oeser A, Raggi P, Stein CM. The ability of the 2013 American College of Cardiology/American Heart Association cardiovascular risk score to identify rheumatoid arthritis patients with high coronary artery calcification scores. Arthritis & Rheumatology (Hoboken, N.J.). 67: 381-5. PMID 25371313 DOI: 10.1002/Art.38944  0.341
2014 Kawai VK, Cunningham A, Vear SI, Van Driest SL, Oginni A, Xu H, Jiang M, Li C, Denny JC, Shaffer C, Bowton E, Gage BF, Ray WA, Roden DM, Stein CM. Genotype and risk of major bleeding during warfarin treatment. Pharmacogenomics. 15: 1973-83. PMID 25521356 DOI: 10.2217/Pgs.14.153  0.361
2014 Iwuchukwu OF, Feng Q, Wei WQ, Jiang L, Jiang M, Xu H, Denny JC, Wilke RA, Krauss RM, Roden DM, Stein CM. Genetic variation in the UGT1A locus is associated with simvastatin efficacy in a clinical practice setting. Pharmacogenomics. 15: 1739-1747. PMID 25493567 DOI: 10.2217/Pgs.14.128  0.636
2014 Caudle KE, Klein TE, Hoffman JM, Muller DJ, Whirl-Carrillo M, Gong L, McDonagh EM, Sangkuhl K, Thorn CF, Schwab M, Agundez JA, Freimuth RR, Huser V, Lee MT, Iwuchukwu OF, ... ... Stein CM, et al. Incorporation of pharmacogenomics into routine clinical practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline development process. Current Drug Metabolism. 15: 209-17. PMID 24479687 DOI: 10.2174/1389200215666140130124910  0.314
2013 Ormseth MJ, Lipson A, Alexopoulos N, Hartlage GR, Oeser AM, Bian A, Gebretsadik T, Shintani A, Raggi P, Stein CM. Association of epicardial adipose tissue with cardiometabolic risk and metabolic syndrome in patients with rheumatoid arthritis. Arthritis Care & Research. 65: 1410-5. PMID 23592527 DOI: 10.1002/Acr.22027  0.31
2012 Lipson A, Alexopoulos N, Hartlage GR, Arepalli C, Oeser A, Bian A, Gebretsadik T, Shintani A, Stillman AE, Stein CM, Raggi P. Epicardial adipose tissue is increased in patients with systemic lupus erythematosus. Atherosclerosis. 223: 389-93. PMID 22770992 DOI: 10.1016/J.Atherosclerosis.2012.06.006  0.301
2012 Bradham WS, Bian A, Oeser A, Gebretsadik T, Shintani A, Solus J, Estis J, Lu QA, Todd J, Raggi P, Stein CM. High-sensitivity cardiac troponin-I is elevated in patients with rheumatoid arthritis, independent of cardiovascular risk factors and inflammation. Plos One. 7: e38930. PMID 22761714 DOI: 10.1371/Journal.Pone.0038930  0.336
2012 Kohli U, Pandharipande P, Muszkat M, Sofowora GG, Friedman EA, Scheinin M, Wood AJ, Ely EW, Tyndale RF, Choi L, Stein CM, Kurnik D. CYP2A6 genetic variation and dexmedetomidine disposition. European Journal of Clinical Pharmacology. 68: 937-42. PMID 22271297 DOI: 10.1007/S00228-011-1208-Z  0.313
2012 Vear SI, Ayers GD, Stein CM, Ho RH. Polymorphisms in VKORC1, CYP2C9, and CYP4F2 and Warfarin Dose in the Pediatric Population Blood. 120: 4358-4358. DOI: 10.1182/Blood.V120.21.4358.4358  0.341
2011 Kawai VK, Grijalva CG, Arbogast PG, Curtis JR, Solomon DH, Delzell E, Chen L, Ouellet-Hellstrom R, Herrinton L, Liu L, Mitchel EF, Stein CM, Griffin MR. Changes in cotherapies after initiation of disease-modifying antirheumatic drug therapy in patients with rheumatoid arthritis. Arthritis Care & Research. 63: 1415-24. PMID 22121511 DOI: 10.1002/Acr.20550  0.306
2011 Gong IY, Tirona RG, Schwarz UI, Crown N, Dresser GK, Larue S, Langlois N, Lazo-Langner A, Zou G, Roden DM, Stein CM, Rodger M, Carrier M, Forgie M, Wells PS, et al. Prospective evaluation of a pharmacogenetics-guided warfarin loading and maintenance dose regimen for initiation of therapy. Blood. 118: 3163-71. PMID 21725053 DOI: 10.1182/Blood-2011-03-345173  0.336
2011 Roden DM, Wilke RA, Kroemer HK, Stein CM. Pharmacogenomics: the genetics of variable drug responses. Circulation. 123: 1661-70. PMID 21502584 DOI: 10.1161/Circulationaha.109.914820  0.335
2011 Cunningham A, Stein CM, Chung CP, Daugherty JR, Smalley WE, Ray WA. An automated database case definition for serious bleeding related to oral anticoagulant use. Pharmacoepidemiology and Drug Safety. 20: 560-6. PMID 21387461 DOI: 10.1002/Pds.2109  0.347
2011 Kurnik D, Muszkat M, Li C, Sofowora GG, Friedman EA, Scheinin M, Wood AJ, Stein CM. Genetic variations in the α(2A)-adrenoreceptor are associated with blood pressure response to the agonist dexmedetomidine. Circulation. Cardiovascular Genetics. 4: 179-87. PMID 21325151 DOI: 10.1161/Circgenetics.110.957662  0.347
2011 Rho YH, Solus J, Raggi P, Oeser A, Gebretsadik T, Shintani A, Stein CM. Macrophage activation and coronary atherosclerosis in systemic lupus erythematosus and rheumatoid arthritis. Arthritis Care & Research. 63: 535-41. PMID 20890983 DOI: 10.1002/Acr.20365  0.321
2010 Holmes DR, Dehmer GJ, Kaul S, Leifer D, O'Gara PT, Stein CM. ACCF/AHA clopidogrel clinical alert: approaches to the FDA "boxed warning": a report of the American College of Cardiology Foundation Task Force on clinical expert consensus documents and the American Heart Association endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons. Journal of the American College of Cardiology. 56: 321-41. PMID 20633831 DOI: 10.1016/J.Jacc.2010.05.013  0.324
2010 Holmes DR, Dehmer GJ, Kaul S, Leifer D, O'Gara PT, Stein CM. ACCF/AHA Clopidogrel clinical alert: approaches to the FDA "boxed warning": a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents and the American Heart Association. Circulation. 122: 537-57. PMID 20585015 DOI: 10.1161/Cir.0B013E3181Ee08Ed  0.322
2010 Rho YH, Chung CP, Oeser A, Solus JF, Gebretsadik T, Shintani A, Raggi P, Milne GL, Stein CM. Interaction between oxidative stress and high-density lipoprotein cholesterol is associated with severity of coronary artery calcification in rheumatoid arthritis. Arthritis Care & Research. 62: 1473-80. PMID 20506360 DOI: 10.1002/Acr.20237  0.302
2010 Muszkat M, Kurnik D, Sofowora GG, Solus J, Xie HG, Harris PA, Williams SM, Wood AJ, Stein CM. Desensitization of vascular response in vivo: contribution of genetic variation in the [alpha]2B-adrenergic receptor subtype. Journal of Hypertension. 28: 278-84. PMID 20051907 DOI: 10.1097/Hjh.0B013E328333D212  0.31
2009 Ray WA, Varas-Lorenzo C, Chung CP, Castellsague J, Murray KT, Stein CM, Daugherty JR, Arbogast PG, García-Rodríguez LA. Cardiovascular risks of nonsteroidal antiinflammatory drugs in patients after hospitalization for serious coronary heart disease. Circulation. Cardiovascular Quality and Outcomes. 2: 155-63. PMID 20031832 DOI: 10.1161/Circoutcomes.108.805689  0.325
2009 Rho YH, Chung CP, Oeser A, Solus J, Asanuma Y, Sokka T, Pincus T, Raggi P, Gebretsadik T, Shintani A, Stein CM. Inflammatory mediators and premature coronary atherosclerosis in rheumatoid arthritis. Arthritis and Rheumatism. 61: 1580-5. PMID 19877084 DOI: 10.1002/Art.25009  0.333
2009 Raj SR, Stein CM, Saavedra PJ, Roden DM. Cardiovascular effects of noncardiovascular drugs. Circulation. 120: 1123-32. PMID 19770411 DOI: 10.1161/Circulationaha.107.728576  0.353
2009 Rho YH, Oeser A, Chung CP, Milne GL, Stein CM. Drugs Used in the Treatment of Rheumatoid Arthritis: Relationship between Current Use and Cardiovascular Risk Factors. Archives of Drug Information. 2: 34-40. PMID 19684849 DOI: 10.1111/J.1753-5174.2009.00019.X  0.348
2009 Rho YH, Solus J, Sokka T, Oeser A, Chung CP, Gebretsadik T, Shintani A, Pincus T, Stein CM. Adipocytokines are associated with radiographic joint damage in rheumatoid arthritis. Arthritis and Rheumatism. 60: 1906-14. PMID 19565493 DOI: 10.1002/Art.24626  0.309
2009 Roden DM, Stein CM. Clopidogrel and the concept of high-risk pharmacokinetics. Circulation. 119: 2127-30. PMID 19398674 DOI: 10.1161/Circulationaha.109.865907  0.394
2009 Ray WA, Chung CP, Murray KT, Hall K, Stein CM. Atypical antipsychotic drugs and the risk of sudden cardiac death. The New England Journal of Medicine. 360: 225-35. PMID 19144938 DOI: 10.1056/Nejmoa0806994  0.314
2009 Li C, Schwarz UI, Ritchie MD, Roden DM, Stein CM, Kurnik D. Relative contribution of CYP2C9 and VKORC1 genotypes and early INR response to the prediction of warfarin sensitivity during initiation of therapy. Blood. 113: 3925-30. PMID 19074728 DOI: 10.1182/Blood-2008-09-176859  0.31
2008 Rho YH, Oeser A, Chung CP, Morrow JD, Stein CM. Drugs to Treat Systemic Lupus Erythematosus: Relationship between Current Use and Cardiovascular Risk Factors. Archives of Drug Information. 1: 23-28. PMID 20157365 DOI: 10.1111/J.1753-5174.2007.00004.X  0.379
2008 Kurnik D, Friedman EA, Muszkat M, Sofowora GG, Xie H, Dupont WD, Wood AJJ, Stein CM. Genetic variants in the α2C-adrenoceptor and G-protein contribute to ethnic differences in cardiovascular stress responses Pharmacogenetics and Genomics. 18: 743-750. PMID 18698227 DOI: 10.1097/Fpc.0B013E3282Fee5A1  0.314
2008 Cooper GM, Johnson JA, Langaee TY, Feng H, Stanaway IB, Schwarz UI, Ritchie MD, Stein CM, Roden DM, Smith JD, Veenstra DL, Rettie AE, Rieder MJ. A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose. Blood. 112: 1022-7. PMID 18535201 DOI: 10.1182/Blood-2008-01-134247  0.342
2008 Ray WA, Stein CM. The aprotinin story--is BART the final chapter? The New England Journal of Medicine. 358: 2398-400. PMID 18480197 DOI: 10.1056/Nejme0803514  0.318
2008 Chung CP, Oeser A, Raggi P, Solus JF, Avalos I, Linton MF, Fazio S, Stein CM. Lipoprotein subclasses and particle size determined by nuclear magnetic resonance spectroscopy in systemic lupus erythematosus. Clinical Rheumatology. 27: 1227-33. PMID 18421545 DOI: 10.1007/S10067-008-0890-4  0.3
2008 Schwarz UI, Ritchie MD, Bradford Y, Li C, Dudek SM, Frye-Anderson A, Kim RB, Roden DM, Stein CM. Genetic determinants of response to warfarin during initial anticoagulation. The New England Journal of Medicine. 358: 999-1008. PMID 18322281 DOI: 10.1056/Nejmoa0708078  0.315
2007 Kurnik D, Muszkat M, Sofowora GG, Friedman EA, Dupont WD, Scheinin M, Wood AJ, Stein CM. Ethnic and genetic determinants of cardiovascular response to the selective alpha 2-adrenoceptor agonist dexmedetomidine. Hypertension (Dallas, Tex. : 1979). 51: 406-11. PMID 18071056 DOI: 10.1161/Hypertensionaha.107.098939  0.304
2007 Avalos I, Chung CP, Oeser A, Milne GL, Borntrager H, Morrow JD, Raggi P, Solus J, Stein CM. Aspirin therapy and thromboxane biosynthesis in systemic lupus erythematosus. Lupus. 16: 981-6. PMID 18042592 DOI: 10.1177/0961203307083313  0.322
2007 Ray WA, Chung CP, Stein CM, Smalley WE, Hall K, Arbogast PG, Griffin MR. Risk of peptic ulcer hospitalizations in users of NSAIDs with gastroprotective cotherapy versus coxibs. Gastroenterology. 133: 790-8. PMID 17854591 DOI: 10.1053/J.Gastro.2007.06.058  0.302
2007 Asanuma Y, Chung CP, Oeser A, Solus JF, Avalos I, Gebretsadik T, Shintani A, Raggi P, Sokka T, Pincus T, Stein CM. Serum osteoprotegerin is increased and independently associated with coronary-artery atherosclerosis in patients with rheumatoid arthritis. Atherosclerosis. 195: e135-41. PMID 17570371 DOI: 10.1016/J.Atherosclerosis.2007.04.049  0.319
2007 Kurnik D, Muszkat M, Friedman EA, Sofowora GG, Diedrich A, Xie HG, Harris PA, Choi L, Wood AJ, Stein CM. Effect of the alpha2C-adrenoreceptor deletion322-325 variant on sympathetic activity and cardiovascular measures in healthy subjects. Journal of Hypertension. 25: 763-71. PMID 17351367 DOI: 10.1097/Hjh.0B013E328017F6E9  0.301
2007 Chung CP, Avalos I, Raggi P, Stein CM. Atherosclerosis and inflammation: insights from rheumatoid arthritis. Clinical Rheumatology. 26: 1228-33. PMID 17273810 DOI: 10.1007/S10067-007-0548-7  0.334
2007 Chung CP, Oeser A, Avalos I, Gebretsadik T, Shintani A, Raggi P, Sokka T, Pincus T, Stein CM. Utility of the Framingham risk score to predict the presence of coronary atherosclerosis in patients with rheumatoid arthritis. Arthritis Research & Therapy. 8: R186. PMID 17169159 DOI: 10.1186/Ar2098  0.345
2006 Chung CP, Avalos I, Oeser A, Gebretsadik T, Shintani A, Raggi P, Stein CM. High prevalence of the metabolic syndrome in patients with systemic lupus erythematosus: association with disease characteristics and cardiovascular risk factors. Annals of the Rheumatic Diseases. 66: 208-214. PMID 16901956 DOI: 10.1136/Ard.2006.054973  0.311
2006 Kurnik D, Muszkat M, Li C, Sofowora GG, Solus J, Xie H, Harris PA, Jiang L, McMunn C, Ihrie P, Dawson EP, Williams SM, Wood AJJ, Stein CM. Variations in the α2A‐adrenergic receptor gene and their functional effects Clinical Pharmacology & Therapeutics. 79: 173-185. PMID 16513442 DOI: 10.1016/J.Clpt.2005.10.006  0.342
2005 Turner E, Dishy V, Chung CP, Harris P, Pierces R, Asanuma Y, Oeser A, Gebretsadik T, Shintani A, Raggi P, Stein CM. Endothelial function in systemic lupus erythematosus: relationship to disease activity, cardiovascular risk factors, corticosteroid therapy, and coronary calcification. Vascular Health and Risk Management. 1: 357-60. PMID 17315608 DOI: 10.2147/Vhrm.2005.1.4.357  0.306
2005 Muszkat M, Kurnik D, Solus J, Sofowora GG, Xie H, Jiang L, Mcmunn C, Ihrie P, Harris JR, Dawson EP, Williams SM, Wood AJJ, Stein CM. Variation in the alpha2B-adrenergic receptor gene (ADRA2B) and its relationship to vascular response in vivo. Pharmacogenetics and Genomics. 15: 407-414. PMID 15900214 DOI: 10.1097/01213011-200506000-00006  0.319
2004 Ray WA, Murray KT, Meredith S, Narasimhulu SS, Hall K, Stein CM. Oral erythromycin and the risk of sudden death from cardiac causes. The New England Journal of Medicine. 351: 1089-96. PMID 15356306 DOI: 10.1056/Nejmoa040582  0.311
2004 Dishy V, Landau R, Sofowora GG, Xie HG, Smiley RM, Kim RB, Byrne DW, Wood AJ, Stein CM. Beta2-adrenoceptor Thr164Ile polymorphism is associated with markedly decreased vasodilator and increased vasoconstrictor sensitivity in vivo. Pharmacogenetics. 14: 517-22. PMID 15284533 DOI: 10.1097/01.Fpc.0000114763.78957.Ec  0.302
2004 Xie HG, Wood AJ, Kim RB, Stein CM, Wilkinson GR. Genetic variability in CYP3A5 and its possible consequences. Pharmacogenomics. 5: 243-72. PMID 15102541 DOI: 10.1517/Phgs.5.3.243.29833  0.329
2003 Xie HG, Prasad HC, Kim RB, Stein CM. CYP2C9 allelic variants: ethnic distribution and functional significance. Advanced Drug Delivery Reviews. 54: 1257-70. PMID 12406644 DOI: 10.1016/S0169-409X(02)00076-5  0.319
2002 Ray WA, Stein CM, Daugherty JR, Hall K, Arbogast PG, Griffin MR. COX-2 selective non-steroidal anti-inflammatory drugs and risk of serious coronary heart disease. Lancet. 360: 1071-3. PMID 12383990 DOI: 10.1016/S0140-6736(02)11131-7  0.305
2002 Smalley W, Stein CM, Arbogast PG, Eisen G, Ray WA, Griffin M. Underutilization of gastroprotective measures in patients receiving nonsteroidal antiinflammatory drugs. Arthritis and Rheumatism. 46: 2195-200. PMID 12209525 DOI: 10.1002/Art.10425  0.315
2002 Ray WA, Stein CM, Hall K, Daugherty JR, Griffin MR. Non-steroidal anti-inflammatory drugs and risk of serious coronary heart disease: an observational cohort study. Lancet. 359: 118-23. PMID 11809254 DOI: 10.1016/S0140-6736(02)07370-1  0.316
2002 Ray WA, Stein CM, Griffin MR. Non-steroidal antiinflammatory drugs and risk of serious coronary heart disease The Lancet. 360: 90. DOI: 10.1016/S0140-6736(02)09349-2  0.32
2001 Xie HG, Kim RB, Wood AJ, Stein CM. Molecular basis of ethnic differences in drug disposition and response. Annual Review of Pharmacology and Toxicology. 41: 815-50. PMID 11264478 DOI: 10.1146/Annurev.Pharmtox.41.1.815  0.322
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