Year |
Citation |
Score |
2023 |
Bhatia V, Maghsoudi S, Hinton M, Bhagirath AY, Singh N, Jaggupilli A, Chelikani P, Dakshinamurti S. Characterization of Adenylyl Cyclase Isoform 6 Residues Interacting with Forskolin. Biology. 12. PMID 37106773 DOI: 10.3390/biology12040572 |
0.722 |
|
2022 |
Bhatia V, de Jesus VC, Shaik FA, Jaggupilli A, Singh N, Chelikani P, Atukorallaya D. Extraoral expression and characterization of bitter taste receptors in (Mexican tetra fish). Faseb Bioadvances. 4: 574-584. PMID 36089978 DOI: 10.1096/fba.2022-00032 |
0.757 |
|
2021 |
Medapati MR, Bhagirath AY, Singh N, Chelikani P. Pharmacology of T2R Mediated Host-Microbe Interactions. Handbook of Experimental Pharmacology. PMID 33580389 DOI: 10.1007/164_2021_435 |
0.364 |
|
2020 |
Singh N, Shaik FA, Myal Y, Chelikani P. Chemosensory bitter taste receptors T2R4 and T2R14 activation attenuates proliferation and migration of breast cancer cells. Molecular and Cellular Biochemistry. PMID 31894529 DOI: 10.1007/S11010-019-03679-5 |
0.349 |
|
2019 |
Shaik FA, Chelikani P. Differential effects of membrane sphingomyelin and cholesterol on agonist-induced bitter taste receptor T2R14 signaling. Molecular and Cellular Biochemistry. PMID 31541354 DOI: 10.1007/S11010-019-03628-2 |
0.432 |
|
2019 |
Shaik FA, Jaggupilli A, Chelikani P. Highly conserved intracellular H208 residue influences agonist selectivity in bitter taste receptor T2R14. Biochimica Et Biophysica Acta. Biomembranes. 1861: 183057. PMID 31493373 DOI: 10.1016/J.Bbamem.2019.183057 |
0.827 |
|
2019 |
Jaggupilli A, Howard R, Aluko RE, Chelikani P. Advanced Glycation End-Products Can Activate or Block Bitter Taste Receptors. Nutrients. 11. PMID 31212814 DOI: 10.3390/Nu11061317 |
0.77 |
|
2019 |
Xu Q, Singh N, Hong H, Yan X, Yu W, Jiang X, Chelikani P, Wu J. Hen protein-derived peptides as the blockers of human bitter taste receptors T2R4, T2R7 and T2R14. Food Chemistry. 283: 621-627. PMID 30722920 DOI: 10.1016/J.Foodchem.2019.01.059 |
0.373 |
|
2019 |
Jappupilli A, Nguyen K, Ly S, Andreeff M, Chelikani P, Battula VL. Abstract 1169: Characterization of a small molecule inhibitor for GD3 synthase (ST8SIA1), a novel target in breast cancer stem-like cells Cancer Research. 79: 1169-1169. DOI: 10.1158/1538-7445.Am2019-1169 |
0.356 |
|
2018 |
Shaik FA, Medapati MR, Chelikani P. Cholesterol modulates signaling of the chemosensory bitter taste receptor T2R14 in human airway cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 30358435 DOI: 10.1152/Ajplung.00169.2018 |
0.476 |
|
2018 |
Sikarwar AS, Hinton M, Santhosh KT, Dhanaraj P, Talabis M, Chelikani P, Dakshinamurti S. Hypoxia inhibits adenylyl cyclase catalytic activity in a porcine model of persistent pulmonary hypertension of the newborn. American Journal of Physiology. Lung Cellular and Molecular Physiology. 315: L933-L944. PMID 30234376 DOI: 10.1152/Ajplung.00130.2018 |
0.38 |
|
2018 |
Jaggupilli A, Singh N, De Jesus VC, Gounni MS, Dhanaraj P, Chelikani P. Chemosensory bitter taste receptors (T2Rs) are activated by multiple antibiotics. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201800521RR. PMID 30011231 DOI: 10.1096/Fj.201800521Rr |
0.802 |
|
2018 |
Jaggupilli A, Singh N, Jesus VC, Duan K, Chelikani P. Characterization of the binding sites for bacterial acyl homoserine lactones (AHLs) on human bitter taste receptors (T2Rs). Acs Infectious Diseases. PMID 29799189 DOI: 10.1021/Acsinfecdis.8B00094 |
0.79 |
|
2018 |
Zhang C, Alashi M, Singh N, Liu K, Chelikani P, Aluko RE. Beef Protein-Derived Peptides as Bitter Taste Receptor T2R4 Blockers. Journal of Agricultural and Food Chemistry. PMID 29706068 DOI: 10.1021/Acs.Jafc.8B00830 |
0.404 |
|
2018 |
Liu K, Jaggupilli A, Premnath D, Chelikani P. Plasticity of the ligand binding pocket in the bitter taste receptor T2R7. Biochimica Et Biophysica Acta. PMID 29355483 DOI: 10.1016/J.Bbamem.2018.01.014 |
0.823 |
|
2018 |
Jaggupilli A, Dhanaraj P, Pritchard A, Sorensen JL, Dakshinamurti S, Chelikani P. Study of adenylyl cyclase-GαS interactions and identification of novel AC ligands. Molecular and Cellular Biochemistry. PMID 29327289 DOI: 10.1007/S11010-018-3273-4 |
0.766 |
|
2017 |
Medapati MR, Singh A, Korupally RR, Henderson D, Klonisch T, Manda SV, Chelikani P. Characterization of GPCRs in extracellular vesicle (EV). Methods in Cell Biology. 142: 119-132. PMID 28964331 DOI: 10.1016/Bs.Mcb.2017.07.004 |
0.404 |
|
2017 |
Chakraborty R, Sikarwar AS, Hinton M, Dakshinamurti S, Chelikani P. Characterization of GPCR signaling in hypoxia. Methods in Cell Biology. 142: 101-110. PMID 28964329 DOI: 10.1016/Bs.Mcb.2017.07.005 |
0.686 |
|
2017 |
Sidhu C, Jaggupilli A, Chelikani P, Bhullar RP. Regulation of Rac1 GTPase activity by quinine through G-protein and bitter taste receptor T2R4. Molecular and Cellular Biochemistry. 426: 129-136. PMID 27873143 DOI: 10.1007/S11010-016-2886-8 |
0.811 |
|
2016 |
Jaggupilli A, Singh N, Upadhyaya J, Sikarwar AS, Arakawa M, Dakshinamurti S, Bhullar RP, Duan K, Chelikani P. Analysis of the expression of human bitter taste receptors in extraoral tissues. Molecular and Cellular Biochemistry. PMID 28012014 DOI: 10.1007/S11010-016-2902-Z |
0.79 |
|
2016 |
Bhagirath AY, Pydi SP, Li Y, Lin C, Kong W, Chelikani P, Duan K. Characterization of the Direct Interaction between Hybrid Sensor Kinases PA1611 and RetS That Controls Biofilm Formation and the Type III Secretion System in Pseudomonas aeruginosa. Acs Infectious Diseases. PMID 27957853 DOI: 10.1021/Acsinfecdis.6B00153 |
0.694 |
|
2016 |
Klonisch T, Glogowska A, Thanasupawat T, Burg M, Krcek J, Pitz M, Jaggupilli A, Chelikani P, Wong GW, Hombach-Klonisch S. Structural commonality of C1q Tumor Necrosis Factor-related proteins and their potential to activate RXFP1 signaling pathways in cancer cells. British Journal of Pharmacology. PMID 27443788 DOI: 10.1111/Bph.13559 |
0.786 |
|
2016 |
Pydi SP, Jafurulla M, Wai L, Bhullar RP, Chelikani P, Chattopadhyay A. Cholesterol modulates bitter taste receptor function. Biochimica Et Biophysica Acta. PMID 27288892 DOI: 10.1016/J.Bbamem.2016.06.005 |
0.761 |
|
2016 |
Upadhyaya JD, Chakraborty R, Shaik FA, Jaggupilli A, Bhullar RP, Chelikani P. The Pharmacochaperone Activity of Quinine on Bitter Taste Receptors. Plos One. 11: e0156347. PMID 27223611 DOI: 10.1371/Journal.Pone.0156347 |
0.812 |
|
2016 |
Shaik FA, Singh N, Arakawa M, Duan K, Bhullar RP, Chelikani P. Bitter taste receptors: Extraoral roles in pathophysiology. The International Journal of Biochemistry & Cell Biology. 77: 197-204. PMID 27032752 DOI: 10.1016/J.Biocel.2016.03.011 |
0.42 |
|
2016 |
Jaggupilli A, Howard R, Upadhyaya JD, Bhullar RP, Chelikani P. Bitter taste receptors: Novel insights into the biochemistry and pharmacology. The International Journal of Biochemistry & Cell Biology. PMID 26995065 DOI: 10.1016/J.Biocel.2016.03.005 |
0.836 |
|
2016 |
Shaik FA, Singh N, Arakawa M, Duan K, Bhullar RP, Chelikani P. Bitter taste receptors: Extraoral roles in pathophysiology International Journal of Biochemistry and Cell Biology. DOI: 10.1016/j.biocel.2016.03.011 |
0.403 |
|
2016 |
Jaggupilli A, Howard R, Upadhyaya JD, Bhullar RP, Chelikani P. Bitter taste receptors: Novel insights into the biochemistry and pharmacology International Journal of Biochemistry and Cell Biology. DOI: 10.1016/j.biocel.2016.03.005 |
0.838 |
|
2015 |
Upadhyaya J, Singh N, Bhullar RP, Chelikani P. The structure-function role of C-terminus in human bitter taste receptor T2R4 signaling. Biochimica Et Biophysica Acta. 1848: 1502-8. PMID 25858111 DOI: 10.1016/J.Bbamem.2015.03.035 |
0.804 |
|
2015 |
Chakraborty R, Xu B, Bhullar RP, Chelikani P. Expression of G protein-coupled receptors in Mammalian cells. Methods in Enzymology. 556: 267-81. PMID 25857786 DOI: 10.1016/Bs.Mie.2014.12.013 |
0.701 |
|
2015 |
Pydi SP, Jaggupilli A, Nelson KM, Abrams SR, Bhullar RP, Loewen MC, Chelikani P. Abscisic Acid Acts as a Blocker of the Bitter Taste G Protein-Coupled Receptor T2R4. Biochemistry. 54: 2622-31. PMID 25844797 DOI: 10.1021/Acs.Biochem.5B00265 |
0.834 |
|
2014 |
Upadhyaya JD, Singh N, Sikarwar AS, Chakraborty R, Pydi SP, Bhullar RP, Dakshinamurti S, Chelikani P. Dextromethorphan mediated bitter taste receptor activation in the pulmonary circuit causes vasoconstriction. Plos One. 9: e110373. PMID 25340739 DOI: 10.1371/Journal.Pone.0110373 |
0.768 |
|
2014 |
Pydi SP, Sobotkiewicz T, Billakanti R, Bhullar RP, Loewen MC, Chelikani P. Amino acid derivatives as bitter taste receptor (T2R) blockers Journal of Biological Chemistry. 289: 25054-25066. PMID 25059668 DOI: 10.1074/Jbc.M114.576975 |
0.772 |
|
2014 |
Pydi SP, Bhullar RP, Chelikani P. Constitutive activity of bitter taste receptors (T2Rs). Advances in Pharmacology (San Diego, Calif.). 70: 303-26. PMID 24931200 DOI: 10.1016/B978-0-12-417197-8.00010-9 |
0.798 |
|
2014 |
Singh N, Chakraborty R, Bhullar RP, Chelikani P. Differential expression of bitter taste receptors in non-cancerous breast epithelial and breast cancer cells. Biochemical and Biophysical Research Communications. 446: 499-503. PMID 24613843 DOI: 10.1016/J.Bbrc.2014.02.140 |
0.66 |
|
2014 |
Santhosh KT, Sikarwar AS, Hinton M, Chelikani P, Dakshinamurti S. Thromboxane receptor hyper‐responsiveness in hypoxic pulmonary hypertension requires serine 324 British Journal of Pharmacology. 171: 676-687. PMID 24490858 DOI: 10.1111/Bph.12487 |
0.512 |
|
2014 |
Chakraborty R, Bhullar RP, Dakshinamurti S, Hwa J, Chelikani P. Inverse agonism of SQ 29,548 and Ramatroban on Thromboxane A2 receptor. Plos One. 9: e85937. PMID 24465800 DOI: 10.1371/Journal.Pone.0085937 |
0.719 |
|
2014 |
Pydi SP, Singh N, Upadhyaya J, Bhullar RP, Chelikani P. The third intracellular loop plays a critical role in bitter taste receptor activation. Biochimica Et Biophysica Acta. 1838: 231-6. PMID 23994601 DOI: 10.1016/J.Bbamem.2013.08.009 |
0.843 |
|
2014 |
Sikarwar AS, Hinton M, Santhosh KT, Chelikani P, Dakshinamurti S. Palmitoylation of Gαq determines its association with the thromboxane receptor in hypoxic pulmonary hypertension. American Journal of Respiratory Cell and Molecular Biology. 50: 135-43. PMID 23962128 DOI: 10.1165/Rcmb.2013-0085Oc |
0.372 |
|
2013 |
Xu B, Chakraborty R, Eilers M, Dakshinamurti S, O'Neil JD, Smith SO, Bhullar RP, Chelikani P. High-level expression, purification and characterization of a constitutively active thromboxane A2 receptor polymorphic variant. Plos One. 8: e76481. PMID 24086743 DOI: 10.1371/Journal.Pone.0076481 |
0.755 |
|
2013 |
Gleim S, Stitham J, Tang WH, Li H, Douville K, Chelikani P, Rade JJ, Martin KA, Hwa J. Human thromboxane A2 receptor genetic variants: in silico, in vitro and "in platelet" analysis. Plos One. 8: e67314. PMID 23840660 DOI: 10.1371/Journal.Pone.0067314 |
0.356 |
|
2013 |
Pydi SP, Chakraborty R, Bhullar RP, Chelikani P. Role of rhodopsin N-terminus in structure and function of rhodopsin-bitter taste receptor chimeras. Biochemical and Biophysical Research Communications. 430: 179-82. PMID 23159609 DOI: 10.1016/J.Bbrc.2012.11.029 |
0.835 |
|
2013 |
Chakraborty R, Pydi SP, Gleim S, Bhullar RP, Hwa J, Dakshinamurti S, Chelikani P. New insights into structural determinants for prostanoid thromboxane A2 receptor- and prostacyclin receptor-G protein coupling. Molecular and Cellular Biology. 33: 184-93. PMID 23109431 DOI: 10.1128/Mcb.00725-12 |
0.82 |
|
2013 |
Gleim S, Stitham J, Tang WH, Li H, Douville K, Chelikani P, Rade JJ, Martin KA, Hwa J. Correction: Human thromboxane A2 receptor genetic variants: In Silico, in Vitro and "in Platelet" analysis (PLoS ONE) Plos One. 8. DOI: 10.1371/Annotation/83Ddfba7-3C48-4C96-8Cd1-0F0B5F69A5D1 |
0.353 |
|
2012 |
Pydi SP, Upadhyaya J, Singh N, Pal Bhullar R, Chelikani P. Recent advances in structure and function studies on human bitter taste receptors. Current Protein & Peptide Science. 13: 501-8. PMID 23061795 DOI: 10.2174/138920312803582942 |
0.842 |
|
2012 |
Xu B, Chelikani P, Bhullar RP. Characterization and functional analysis of the calmodulin-binding domain of Rac1 GTPase. Plos One. 7: e42975. PMID 22905193 DOI: 10.1371/Journal.Pone.0042975 |
0.415 |
|
2012 |
Jha V, Chelikani P, Carpena X, Fita I, Loewen PC. Influence of main channel structure on H(2)O(2) access to the heme cavity of catalase KatE of Escherichia coli. Archives of Biochemistry and Biophysics. 526: 54-9. PMID 22820098 DOI: 10.1016/J.Abb.2012.06.010 |
0.569 |
|
2012 |
Pydi SP, Bhullar RP, Chelikani P. Constitutively active mutant gives novel insights into the mechanism of bitter taste receptor activation. Journal of Neurochemistry. 122: 537-44. PMID 22639948 DOI: 10.1111/J.1471-4159.2012.07808.X |
0.777 |
|
2012 |
Chakraborty R, Pydi SP, Gleim S, Dakshinamurti S, Hwa J, Chelikani P. Site-directed mutations and the polymorphic variant Ala160Thr in the human thromboxane receptor uncover a structural role for transmembrane helix 4. Plos One. 7: e29996. PMID 22272267 DOI: 10.1371/Journal.Pone.0029996 |
0.823 |
|
2011 |
Singh N, Pydi SP, Upadhyaya J, Chelikani P. Structural basis of activation of bitter taste receptor T2R1 and comparison with Class A G-protein-coupled receptors (GPCRs). The Journal of Biological Chemistry. 286: 36032-36041. PMID 21852241 DOI: 10.1074/Jbc.M111.246983 |
0.847 |
|
2011 |
Jha V, Louis S, Chelikani P, Carpena X, Donald LJ, Fita I, Loewen PC. Modulation of heme orientation and binding by a single residue in catalase HPII of Escherichia coli. Biochemistry. 50: 2101-10. PMID 21332158 DOI: 10.1021/Bi200027V |
0.583 |
|
2011 |
Singh N, Vrontakis M, Parkinson F, Chelikani P. Functional bitter taste receptors are expressed in brain cells. Biochemical and Biophysical Research Communications. 406: 146-51. PMID 21303656 DOI: 10.1016/J.Bbrc.2011.02.016 |
0.484 |
|
2011 |
Arakawa M, Chakraborty R, Upadhyaya J, Eilers M, Reeves PJ, Smith SO, Chelikani P. Structural and functional roles of small group-conserved amino acids present on helix-H7 in the β(2)-adrenergic receptor. Biochimica Et Biophysica Acta. 1808: 1170-8. PMID 21262196 DOI: 10.1016/J.Bbamem.2011.01.012 |
0.827 |
|
2010 |
Upadhyaya J, Pydi SP, Singh N, Aluko RE, Chelikani P. Bitter taste receptor T2R1 is activated by dipeptides and tripeptides. Biochemical and Biophysical Research Communications. 398: 331-5. PMID 20599705 DOI: 10.1016/J.Bbrc.2010.06.097 |
0.814 |
|
2010 |
Arakawa M, Yanamala N, Upadhyaya J, Halayko A, Klein-Seetharaman J, Chelikani P. The importance of valine 114 in ligand binding in beta(2)-adrenergic receptor. Protein Science : a Publication of the Protein Society. 19: 85-93. PMID 19916165 DOI: 10.1002/Pro.285 |
0.788 |
|
2008 |
Takayama H, Chelikani P, Reeves PJ, Zhang S, Khorana HG. High-level expression, single-step immunoaffinity purification and characterization of human tetraspanin membrane protein CD81. Plos One. 3: e2314. PMID 18523555 DOI: 10.1371/Journal.Pone.0002314 |
0.548 |
|
2007 |
Chelikani P, Hornak V, Eilers M, Reeves PJ, Smith SO, RajBhandary UL, Khorana HG. Role of group-conserved residues in the helical core of beta2-adrenergic receptor. Proceedings of the National Academy of Sciences of the United States of America. 104: 7027-32. PMID 17438264 DOI: 10.1073/Pnas.0702024104 |
0.759 |
|
2006 |
Chelikani P, Reeves PJ, Rajbhandary UL, Khorana HG. The synthesis and high-level expression of a beta2-adrenergic receptor gene in a tetracycline-inducible stable mammalian cell line. Protein Science : a Publication of the Protein Society. 15: 1433-40. PMID 16731977 DOI: 10.1110/Ps.062080006 |
0.675 |
|
2005 |
Chelikani P, Ramana T, Radhakrishnan TM. Catalase: A repertoire of unusual features. Indian Journal of Clinical Biochemistry : Ijcb. 20: 131-5. PMID 23105545 DOI: 10.1007/Bf02867412 |
0.309 |
|
2005 |
Chelikani P, Carpena X, Perez-Luque R, Donald LJ, Duckworth HW, Switala J, Fita I, Loewen PC. Characterization of a large subunit catalase truncated by proteolytic cleavage. Biochemistry. 44: 5597-605. PMID 15823018 DOI: 10.1021/Bi047277M |
0.613 |
|
2003 |
Chelikani P, Carpena X, Fita I, Loewen PC. An electrical potential in the access channel of catalases enhances catalysis. The Journal of Biological Chemistry. 278: 31290-6. PMID 12777389 DOI: 10.1074/Jbc.M304076200 |
0.593 |
|
2003 |
Chelikani P, Donald LJ, Duckworth HW, Loewen PC. Hydroperoxidase II of Escherichia coli exhibits enhanced resistance to proteolytic cleavage compared to other catalases. Biochemistry. 42: 5729-35. PMID 12741830 DOI: 10.1021/Bi034208J |
0.581 |
|
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