Prashen Chelikani - Publications

Affiliations: 
University of Manitoba, Winnipeg, Manitoba, Canada 
Area:
Taste biology, Chemosensation

62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Bhatia V, Maghsoudi S, Hinton M, Bhagirath AY, Singh N, Jaggupilli A, Chelikani P, Dakshinamurti S. Characterization of Adenylyl Cyclase Isoform 6 Residues Interacting with Forskolin. Biology. 12. PMID 37106773 DOI: 10.3390/biology12040572  0.722
2022 Bhatia V, de Jesus VC, Shaik FA, Jaggupilli A, Singh N, Chelikani P, Atukorallaya D. Extraoral expression and characterization of bitter taste receptors in (Mexican tetra fish). Faseb Bioadvances. 4: 574-584. PMID 36089978 DOI: 10.1096/fba.2022-00032  0.757
2021 Medapati MR, Bhagirath AY, Singh N, Chelikani P. Pharmacology of T2R Mediated Host-Microbe Interactions. Handbook of Experimental Pharmacology. PMID 33580389 DOI: 10.1007/164_2021_435  0.364
2020 Singh N, Shaik FA, Myal Y, Chelikani P. Chemosensory bitter taste receptors T2R4 and T2R14 activation attenuates proliferation and migration of breast cancer cells. Molecular and Cellular Biochemistry. PMID 31894529 DOI: 10.1007/S11010-019-03679-5  0.349
2019 Shaik FA, Chelikani P. Differential effects of membrane sphingomyelin and cholesterol on agonist-induced bitter taste receptor T2R14 signaling. Molecular and Cellular Biochemistry. PMID 31541354 DOI: 10.1007/S11010-019-03628-2  0.432
2019 Shaik FA, Jaggupilli A, Chelikani P. Highly conserved intracellular H208 residue influences agonist selectivity in bitter taste receptor T2R14. Biochimica Et Biophysica Acta. Biomembranes. 1861: 183057. PMID 31493373 DOI: 10.1016/J.Bbamem.2019.183057  0.827
2019 Jaggupilli A, Howard R, Aluko RE, Chelikani P. Advanced Glycation End-Products Can Activate or Block Bitter Taste Receptors. Nutrients. 11. PMID 31212814 DOI: 10.3390/Nu11061317  0.77
2019 Xu Q, Singh N, Hong H, Yan X, Yu W, Jiang X, Chelikani P, Wu J. Hen protein-derived peptides as the blockers of human bitter taste receptors T2R4, T2R7 and T2R14. Food Chemistry. 283: 621-627. PMID 30722920 DOI: 10.1016/J.Foodchem.2019.01.059  0.373
2019 Jappupilli A, Nguyen K, Ly S, Andreeff M, Chelikani P, Battula VL. Abstract 1169: Characterization of a small molecule inhibitor for GD3 synthase (ST8SIA1), a novel target in breast cancer stem-like cells Cancer Research. 79: 1169-1169. DOI: 10.1158/1538-7445.Am2019-1169  0.356
2018 Shaik FA, Medapati MR, Chelikani P. Cholesterol modulates signaling of the chemosensory bitter taste receptor T2R14 in human airway cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 30358435 DOI: 10.1152/Ajplung.00169.2018  0.476
2018 Sikarwar AS, Hinton M, Santhosh KT, Dhanaraj P, Talabis M, Chelikani P, Dakshinamurti S. Hypoxia inhibits adenylyl cyclase catalytic activity in a porcine model of persistent pulmonary hypertension of the newborn. American Journal of Physiology. Lung Cellular and Molecular Physiology. 315: L933-L944. PMID 30234376 DOI: 10.1152/Ajplung.00130.2018  0.38
2018 Jaggupilli A, Singh N, De Jesus VC, Gounni MS, Dhanaraj P, Chelikani P. Chemosensory bitter taste receptors (T2Rs) are activated by multiple antibiotics. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201800521RR. PMID 30011231 DOI: 10.1096/Fj.201800521Rr  0.802
2018 Jaggupilli A, Singh N, Jesus VC, Duan K, Chelikani P. Characterization of the binding sites for bacterial acyl homoserine lactones (AHLs) on human bitter taste receptors (T2Rs). Acs Infectious Diseases. PMID 29799189 DOI: 10.1021/Acsinfecdis.8B00094  0.79
2018 Zhang C, Alashi M, Singh N, Liu K, Chelikani P, Aluko RE. Beef Protein-Derived Peptides as Bitter Taste Receptor T2R4 Blockers. Journal of Agricultural and Food Chemistry. PMID 29706068 DOI: 10.1021/Acs.Jafc.8B00830  0.404
2018 Liu K, Jaggupilli A, Premnath D, Chelikani P. Plasticity of the ligand binding pocket in the bitter taste receptor T2R7. Biochimica Et Biophysica Acta. PMID 29355483 DOI: 10.1016/J.Bbamem.2018.01.014  0.823
2018 Jaggupilli A, Dhanaraj P, Pritchard A, Sorensen JL, Dakshinamurti S, Chelikani P. Study of adenylyl cyclase-GαS interactions and identification of novel AC ligands. Molecular and Cellular Biochemistry. PMID 29327289 DOI: 10.1007/S11010-018-3273-4  0.766
2017 Medapati MR, Singh A, Korupally RR, Henderson D, Klonisch T, Manda SV, Chelikani P. Characterization of GPCRs in extracellular vesicle (EV). Methods in Cell Biology. 142: 119-132. PMID 28964331 DOI: 10.1016/Bs.Mcb.2017.07.004  0.404
2017 Chakraborty R, Sikarwar AS, Hinton M, Dakshinamurti S, Chelikani P. Characterization of GPCR signaling in hypoxia. Methods in Cell Biology. 142: 101-110. PMID 28964329 DOI: 10.1016/Bs.Mcb.2017.07.005  0.686
2017 Sidhu C, Jaggupilli A, Chelikani P, Bhullar RP. Regulation of Rac1 GTPase activity by quinine through G-protein and bitter taste receptor T2R4. Molecular and Cellular Biochemistry. 426: 129-136. PMID 27873143 DOI: 10.1007/S11010-016-2886-8  0.811
2016 Jaggupilli A, Singh N, Upadhyaya J, Sikarwar AS, Arakawa M, Dakshinamurti S, Bhullar RP, Duan K, Chelikani P. Analysis of the expression of human bitter taste receptors in extraoral tissues. Molecular and Cellular Biochemistry. PMID 28012014 DOI: 10.1007/S11010-016-2902-Z  0.79
2016 Bhagirath AY, Pydi SP, Li Y, Lin C, Kong W, Chelikani P, Duan K. Characterization of the Direct Interaction between Hybrid Sensor Kinases PA1611 and RetS That Controls Biofilm Formation and the Type III Secretion System in Pseudomonas aeruginosa. Acs Infectious Diseases. PMID 27957853 DOI: 10.1021/Acsinfecdis.6B00153  0.694
2016 Klonisch T, Glogowska A, Thanasupawat T, Burg M, Krcek J, Pitz M, Jaggupilli A, Chelikani P, Wong GW, Hombach-Klonisch S. Structural commonality of C1q Tumor Necrosis Factor-related proteins and their potential to activate RXFP1 signaling pathways in cancer cells. British Journal of Pharmacology. PMID 27443788 DOI: 10.1111/Bph.13559  0.786
2016 Pydi SP, Jafurulla M, Wai L, Bhullar RP, Chelikani P, Chattopadhyay A. Cholesterol modulates bitter taste receptor function. Biochimica Et Biophysica Acta. PMID 27288892 DOI: 10.1016/J.Bbamem.2016.06.005  0.761
2016 Upadhyaya JD, Chakraborty R, Shaik FA, Jaggupilli A, Bhullar RP, Chelikani P. The Pharmacochaperone Activity of Quinine on Bitter Taste Receptors. Plos One. 11: e0156347. PMID 27223611 DOI: 10.1371/Journal.Pone.0156347  0.812
2016 Shaik FA, Singh N, Arakawa M, Duan K, Bhullar RP, Chelikani P. Bitter taste receptors: Extraoral roles in pathophysiology. The International Journal of Biochemistry & Cell Biology. 77: 197-204. PMID 27032752 DOI: 10.1016/J.Biocel.2016.03.011  0.42
2016 Jaggupilli A, Howard R, Upadhyaya JD, Bhullar RP, Chelikani P. Bitter taste receptors: Novel insights into the biochemistry and pharmacology. The International Journal of Biochemistry & Cell Biology. PMID 26995065 DOI: 10.1016/J.Biocel.2016.03.005  0.836
2016 Shaik FA, Singh N, Arakawa M, Duan K, Bhullar RP, Chelikani P. Bitter taste receptors: Extraoral roles in pathophysiology International Journal of Biochemistry and Cell Biology. DOI: 10.1016/j.biocel.2016.03.011  0.403
2016 Jaggupilli A, Howard R, Upadhyaya JD, Bhullar RP, Chelikani P. Bitter taste receptors: Novel insights into the biochemistry and pharmacology International Journal of Biochemistry and Cell Biology. DOI: 10.1016/j.biocel.2016.03.005  0.838
2015 Upadhyaya J, Singh N, Bhullar RP, Chelikani P. The structure-function role of C-terminus in human bitter taste receptor T2R4 signaling. Biochimica Et Biophysica Acta. 1848: 1502-8. PMID 25858111 DOI: 10.1016/J.Bbamem.2015.03.035  0.804
2015 Chakraborty R, Xu B, Bhullar RP, Chelikani P. Expression of G protein-coupled receptors in Mammalian cells. Methods in Enzymology. 556: 267-81. PMID 25857786 DOI: 10.1016/Bs.Mie.2014.12.013  0.701
2015 Pydi SP, Jaggupilli A, Nelson KM, Abrams SR, Bhullar RP, Loewen MC, Chelikani P. Abscisic Acid Acts as a Blocker of the Bitter Taste G Protein-Coupled Receptor T2R4. Biochemistry. 54: 2622-31. PMID 25844797 DOI: 10.1021/Acs.Biochem.5B00265  0.834
2014 Upadhyaya JD, Singh N, Sikarwar AS, Chakraborty R, Pydi SP, Bhullar RP, Dakshinamurti S, Chelikani P. Dextromethorphan mediated bitter taste receptor activation in the pulmonary circuit causes vasoconstriction. Plos One. 9: e110373. PMID 25340739 DOI: 10.1371/Journal.Pone.0110373  0.768
2014 Pydi SP, Sobotkiewicz T, Billakanti R, Bhullar RP, Loewen MC, Chelikani P. Amino acid derivatives as bitter taste receptor (T2R) blockers Journal of Biological Chemistry. 289: 25054-25066. PMID 25059668 DOI: 10.1074/Jbc.M114.576975  0.772
2014 Pydi SP, Bhullar RP, Chelikani P. Constitutive activity of bitter taste receptors (T2Rs). Advances in Pharmacology (San Diego, Calif.). 70: 303-26. PMID 24931200 DOI: 10.1016/B978-0-12-417197-8.00010-9  0.798
2014 Singh N, Chakraborty R, Bhullar RP, Chelikani P. Differential expression of bitter taste receptors in non-cancerous breast epithelial and breast cancer cells. Biochemical and Biophysical Research Communications. 446: 499-503. PMID 24613843 DOI: 10.1016/J.Bbrc.2014.02.140  0.66
2014 Santhosh KT, Sikarwar AS, Hinton M, Chelikani P, Dakshinamurti S. Thromboxane receptor hyper‐responsiveness in hypoxic pulmonary hypertension requires serine 324 British Journal of Pharmacology. 171: 676-687. PMID 24490858 DOI: 10.1111/Bph.12487  0.512
2014 Chakraborty R, Bhullar RP, Dakshinamurti S, Hwa J, Chelikani P. Inverse agonism of SQ 29,548 and Ramatroban on Thromboxane A2 receptor. Plos One. 9: e85937. PMID 24465800 DOI: 10.1371/Journal.Pone.0085937  0.719
2014 Pydi SP, Singh N, Upadhyaya J, Bhullar RP, Chelikani P. The third intracellular loop plays a critical role in bitter taste receptor activation. Biochimica Et Biophysica Acta. 1838: 231-6. PMID 23994601 DOI: 10.1016/J.Bbamem.2013.08.009  0.843
2014 Sikarwar AS, Hinton M, Santhosh KT, Chelikani P, Dakshinamurti S. Palmitoylation of Gαq determines its association with the thromboxane receptor in hypoxic pulmonary hypertension. American Journal of Respiratory Cell and Molecular Biology. 50: 135-43. PMID 23962128 DOI: 10.1165/Rcmb.2013-0085Oc  0.372
2013 Xu B, Chakraborty R, Eilers M, Dakshinamurti S, O'Neil JD, Smith SO, Bhullar RP, Chelikani P. High-level expression, purification and characterization of a constitutively active thromboxane A2 receptor polymorphic variant. Plos One. 8: e76481. PMID 24086743 DOI: 10.1371/Journal.Pone.0076481  0.755
2013 Gleim S, Stitham J, Tang WH, Li H, Douville K, Chelikani P, Rade JJ, Martin KA, Hwa J. Human thromboxane A2 receptor genetic variants: in silico, in vitro and "in platelet" analysis. Plos One. 8: e67314. PMID 23840660 DOI: 10.1371/Journal.Pone.0067314  0.356
2013 Pydi SP, Chakraborty R, Bhullar RP, Chelikani P. Role of rhodopsin N-terminus in structure and function of rhodopsin-bitter taste receptor chimeras. Biochemical and Biophysical Research Communications. 430: 179-82. PMID 23159609 DOI: 10.1016/J.Bbrc.2012.11.029  0.835
2013 Chakraborty R, Pydi SP, Gleim S, Bhullar RP, Hwa J, Dakshinamurti S, Chelikani P. New insights into structural determinants for prostanoid thromboxane A2 receptor- and prostacyclin receptor-G protein coupling. Molecular and Cellular Biology. 33: 184-93. PMID 23109431 DOI: 10.1128/Mcb.00725-12  0.82
2013 Gleim S, Stitham J, Tang WH, Li H, Douville K, Chelikani P, Rade JJ, Martin KA, Hwa J. Correction: Human thromboxane A2 receptor genetic variants: In Silico, in Vitro and "in Platelet" analysis (PLoS ONE) Plos One. 8. DOI: 10.1371/Annotation/83Ddfba7-3C48-4C96-8Cd1-0F0B5F69A5D1  0.353
2012 Pydi SP, Upadhyaya J, Singh N, Pal Bhullar R, Chelikani P. Recent advances in structure and function studies on human bitter taste receptors. Current Protein & Peptide Science. 13: 501-8. PMID 23061795 DOI: 10.2174/138920312803582942  0.842
2012 Xu B, Chelikani P, Bhullar RP. Characterization and functional analysis of the calmodulin-binding domain of Rac1 GTPase. Plos One. 7: e42975. PMID 22905193 DOI: 10.1371/Journal.Pone.0042975  0.415
2012 Jha V, Chelikani P, Carpena X, Fita I, Loewen PC. Influence of main channel structure on H(2)O(2) access to the heme cavity of catalase KatE of Escherichia coli. Archives of Biochemistry and Biophysics. 526: 54-9. PMID 22820098 DOI: 10.1016/J.Abb.2012.06.010  0.569
2012 Pydi SP, Bhullar RP, Chelikani P. Constitutively active mutant gives novel insights into the mechanism of bitter taste receptor activation. Journal of Neurochemistry. 122: 537-44. PMID 22639948 DOI: 10.1111/J.1471-4159.2012.07808.X  0.777
2012 Chakraborty R, Pydi SP, Gleim S, Dakshinamurti S, Hwa J, Chelikani P. Site-directed mutations and the polymorphic variant Ala160Thr in the human thromboxane receptor uncover a structural role for transmembrane helix 4. Plos One. 7: e29996. PMID 22272267 DOI: 10.1371/Journal.Pone.0029996  0.823
2011 Singh N, Pydi SP, Upadhyaya J, Chelikani P. Structural basis of activation of bitter taste receptor T2R1 and comparison with Class A G-protein-coupled receptors (GPCRs). The Journal of Biological Chemistry. 286: 36032-36041. PMID 21852241 DOI: 10.1074/Jbc.M111.246983  0.847
2011 Jha V, Louis S, Chelikani P, Carpena X, Donald LJ, Fita I, Loewen PC. Modulation of heme orientation and binding by a single residue in catalase HPII of Escherichia coli. Biochemistry. 50: 2101-10. PMID 21332158 DOI: 10.1021/Bi200027V  0.583
2011 Singh N, Vrontakis M, Parkinson F, Chelikani P. Functional bitter taste receptors are expressed in brain cells. Biochemical and Biophysical Research Communications. 406: 146-51. PMID 21303656 DOI: 10.1016/J.Bbrc.2011.02.016  0.484
2011 Arakawa M, Chakraborty R, Upadhyaya J, Eilers M, Reeves PJ, Smith SO, Chelikani P. Structural and functional roles of small group-conserved amino acids present on helix-H7 in the β(2)-adrenergic receptor. Biochimica Et Biophysica Acta. 1808: 1170-8. PMID 21262196 DOI: 10.1016/J.Bbamem.2011.01.012  0.827
2010 Upadhyaya J, Pydi SP, Singh N, Aluko RE, Chelikani P. Bitter taste receptor T2R1 is activated by dipeptides and tripeptides. Biochemical and Biophysical Research Communications. 398: 331-5. PMID 20599705 DOI: 10.1016/J.Bbrc.2010.06.097  0.814
2010 Arakawa M, Yanamala N, Upadhyaya J, Halayko A, Klein-Seetharaman J, Chelikani P. The importance of valine 114 in ligand binding in beta(2)-adrenergic receptor. Protein Science : a Publication of the Protein Society. 19: 85-93. PMID 19916165 DOI: 10.1002/Pro.285  0.788
2008 Takayama H, Chelikani P, Reeves PJ, Zhang S, Khorana HG. High-level expression, single-step immunoaffinity purification and characterization of human tetraspanin membrane protein CD81. Plos One. 3: e2314. PMID 18523555 DOI: 10.1371/Journal.Pone.0002314  0.548
2007 Chelikani P, Hornak V, Eilers M, Reeves PJ, Smith SO, RajBhandary UL, Khorana HG. Role of group-conserved residues in the helical core of beta2-adrenergic receptor. Proceedings of the National Academy of Sciences of the United States of America. 104: 7027-32. PMID 17438264 DOI: 10.1073/Pnas.0702024104  0.759
2006 Chelikani P, Reeves PJ, Rajbhandary UL, Khorana HG. The synthesis and high-level expression of a beta2-adrenergic receptor gene in a tetracycline-inducible stable mammalian cell line. Protein Science : a Publication of the Protein Society. 15: 1433-40. PMID 16731977 DOI: 10.1110/Ps.062080006  0.675
2005 Chelikani P, Ramana T, Radhakrishnan TM. Catalase: A repertoire of unusual features. Indian Journal of Clinical Biochemistry : Ijcb. 20: 131-5. PMID 23105545 DOI: 10.1007/Bf02867412  0.309
2005 Chelikani P, Carpena X, Perez-Luque R, Donald LJ, Duckworth HW, Switala J, Fita I, Loewen PC. Characterization of a large subunit catalase truncated by proteolytic cleavage. Biochemistry. 44: 5597-605. PMID 15823018 DOI: 10.1021/Bi047277M  0.613
2003 Chelikani P, Carpena X, Fita I, Loewen PC. An electrical potential in the access channel of catalases enhances catalysis. The Journal of Biological Chemistry. 278: 31290-6. PMID 12777389 DOI: 10.1074/Jbc.M304076200  0.593
2003 Chelikani P, Donald LJ, Duckworth HW, Loewen PC. Hydroperoxidase II of Escherichia coli exhibits enhanced resistance to proteolytic cleavage compared to other catalases. Biochemistry. 42: 5729-35. PMID 12741830 DOI: 10.1021/Bi034208J  0.581
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