| Year |
Citation |
Score |
| 2004 |
Sackellares JC, Ramsay RE, Wilder BJ, Browne TR, Shellenberger MK. Randomized, controlled clinical trial of zonisamide as adjunctive treatment for refractory partial seizures. Epilepsia. 45: 610-7. PMID 15144425 DOI: 10.1111/J.0013-9580.2004.11403.X |
0.307 |
|
| 2004 |
French JA, Kanner AM, Bautista J, Abou-Khalil B, Browne T, Harden CL, Theodore WH, Bazil C, Stern J, Schachter SC, Bergen D, Hirtz D, Montouris GD, Nespeca M, Gidal B, et al. Efficacy and tolerability of the new antiepileptic drugs II: treatment of refractory epilepsy: report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Neurology. 62: 1261-73. PMID 15111660 DOI: 10.1212/01.Wnl.0000123695.22623.32 |
0.339 |
|
| 2004 |
French JA, Kanner AM, Bautista J, Abou-Khalil B, Browne T, Harden CL, Theodore WH, Bazil C, Stern J, Schachter SC, Bergen D, Hirtz D, Montouris GD, Nespeca M, Gidal B, et al. Efficacy and tolerability of the new antiepileptic drugs, I: Treatment of new-onset epilepsy: report of the TTA and QSS Subcommittees of the American Academy of Neurology and the American Epilepsy Society. Epilepsia. 45: 401-9. PMID 15101821 DOI: 10.1111/J.0013-9580.2004.06204.X |
0.381 |
|
| 2004 |
French J, Kanner AM, Bautista J, Abou-Khalil B, Browne T, Harden CL, Theodore WH, Bazil C, Stern J, Schachter SC, Bergen D, Hirtz D, Montouris GD, Nespeca M, Gidal B, et al. Erratum: Efficacy and tolerability of the new antiepileptic drugs, II: Treatment of refractory epilepsy. Report of the TTA and QSS subcommittees of the American Academy of Neurology and the American Epilepsy Society (Epilepsia (2004) 45 (410-423)) Epilepsia. 45. DOI: 10.1111/J.0013-9580.2004.20041020.X |
0.357 |
|
| 2003 |
Coupez R, Nicolas JM, Browne TR. Levetiracetam, a new antiepileptic agent: lack of in vitro and in vivo pharmacokinetic interaction with valproic acid. Epilepsia. 44: 171-8. PMID 12558570 DOI: 10.1046/J.1528-1157.2003.25302.X |
0.408 |
|
| 2000 |
Durso R, Evans JE, Josephs E, Szabo G, Evans B, Fernandez HH, Browne TR. Variable absorption of carbidopa affects both peripheral and central levodopa metabolism. Journal of Clinical Pharmacology. 40: 854-60. PMID 10934669 DOI: 10.1177/00912700022009585 |
0.305 |
|
| 2000 |
Browne TR, Szabo GK, Leppik IE, Josephs E, Paz J, Baltes E, Jensen CM. Absence of pharmacokinetic drug interaction of levetiracetam with phenytoin in patients with epilepsy determined by new technique. The Journal of Clinical Pharmacology. 40: 590-595. DOI: 10.1002/J.1552-4604.2000.Tb05984.X |
0.445 |
|
| 1998 |
Browne TR. Pharmacokinetics of antiepileptic drugs Neurology. 51. PMID 9818917 DOI: 10.1212/Wnl.51.5_Suppl_4.S2 |
0.476 |
|
| 1998 |
Browne TR, Szabo GK, Ajami A, Browne DG. Performance of Human Mass Balance Studies with Stable Isotope‐Labeled Drug and Continuous Flow‐Isotope Ratio Mass Spectrometry: A Progress Report The Journal of Clinical Pharmacology. 38: 309-314. PMID 9590457 DOI: 10.1002/J.1552-4604.1998.Tb04429.X |
0.4 |
|
| 1998 |
Browne TR. Stable Isotope Techniques in Early Drug Development: An Economic Evaluation The Journal of Clinical Pharmacology. 38: 213-220. PMID 9549659 DOI: 10.1002/J.1552-4604.1998.Tb04418.X |
0.434 |
|
| 1997 |
Durso R, Evans JE, Josephs E, Szabo GK, Evans BA, Handler JS, Jennings D, Browne TR. Central levodopa metabolism in Parkinson's disease after administration of stable isotope-labeled levodopa. Annals of Neurology. 42: 300-4. PMID 9307250 DOI: 10.1002/Ana.410420305 |
0.356 |
|
| 1997 |
Browne TR. Chapter 24 Stable isotope techniques in drug development: An economic evaluation Pharmacochemistry Library. 26: 417-428. DOI: 10.1016/S0165-7208(97)80171-7 |
0.466 |
|
| 1997 |
Browne TR. Chapter 23 Regulatory aspects Pharmacochemistry Library. 26: 411-416. DOI: 10.1016/S0165-7208(97)80170-5 |
0.412 |
|
| 1997 |
Browne TR, Szabo GK, Ajami AM. Chapter 22 Procurement of stable isotope-labeled pharmaceuticals Pharmacochemistry Library. 26: 405-409. DOI: 10.1016/S0165-7208(97)80169-9 |
0.42 |
|
| 1997 |
Browne TR. Chapter 18 Drug interactions Pharmacochemistry Library. 26: 337-346. DOI: 10.1016/S0165-7208(97)80165-1 |
0.478 |
|
| 1997 |
Browne TR. Chapter 16 Biotransformation and excretion: Pharmacokinetic studies Pharmacochemistry Library. 26: 297-314. DOI: 10.1016/S0165-7208(97)80163-8 |
0.448 |
|
| 1997 |
Browne TR. Chapter 14 Drug distribution and “Deep pool effect” Pharmacochemistry Library. 26: 261-274. DOI: 10.1016/S0165-7208(97)80161-4 |
0.473 |
|
| 1997 |
Browne TR, Szabo GK, Ajami A. Chapter 11 Mass balance Pharmacochemistry Library. 26: 219-232. DOI: 10.1016/S0165-7208(97)80158-4 |
0.409 |
|
| 1997 |
Szabo GK, Perchalski RJ, Browne DG, Browne TR. Chapter 7 alternatives to mass spectrometry for quantitation of stable isotopes: High performance liquid chromatography with conventional ultraviolet detection Pharmacochemistry Library. 26: 127-140. DOI: 10.1016/S0165-7208(97)80154-7 |
0.331 |
|
| 1997 |
Browne TR, Szabo GK, Ajami A. Chapter 6 Mass spectrometry: Isotope ratio mass spectrometry Pharmacochemistry Library. 26: 119-125. DOI: 10.1016/S0165-7208(97)80153-5 |
0.328 |
|
| 1996 |
Browne TR, Kugler AR, Eldon MA. Pharmacology and pharmacokinetics of fosphenytoin Neurology. 46. PMID 8649612 DOI: 10.1212/Wnl.46.6_Suppl_1.3S |
0.342 |
|
| 1994 |
Browne TR, Szabo GK, Davoudi H, Josephs EG. Determination of pharmacokinetic drug interactions with carbamazepine and phenytoin using stable isotope labeling and simple high-performance liquid chromatography/ultraviolet detection technique. Neurology. 44: 2410-1. PMID 7991143 DOI: 10.1212/Wnl.44.12.2410 |
0.395 |
|
| 1993 |
Browne TR, Szabo GK, Ajami A, Wagner D. Performance of human mass balance/metabolite identification studies using stable isotope (13C, 15N) labeling and continuous-flow isotope-ratio mass spectrometry as an alternative to radioactive labeling methods. The Journal of Clinical Pharmacology. 33: 246-252. PMID 8463438 DOI: 10.1002/J.1552-4604.1993.Tb03951.X |
0.4 |
|
| 1993 |
Browne TR, Szabo GK, McEntegart C, Evans JE, Evans BA, Miceli JJ, Quon C, Dougherty CL, Kres J, Davoudi H. Bioavailability studies of drugs with nonlinear pharmacokinetics: II. Absolute bioavailability of intravenous phenytoin prodrug at therapeutic phenytoin serum concentrations determined by double-stable isotope technique. Journal of Clinical Pharmacology. 33: 89-94. PMID 8429121 DOI: 10.1002/J.1552-4604.1993.Tb03910.X |
0.408 |
|
| 1992 |
Browne TR, Szabo GK, Schumacher GE, Greenblatt DJ, Evans JE, Evans BA. Bioavailability studies of drugs with nonlinear pharmacokinetics: I. Tracer dose AUC varies directly with serum concentration. The Journal of Clinical Pharmacology. 32: 1141-1145. DOI: 10.1177/009127009203201214 |
0.443 |
|
| 1991 |
Ludden TM, Allerheiligen SRB, Browne TR, Koup JR. Sensitivity analysis of the effect of bioavailability or dosage form content on mean steady state phenytoin concentration Therapeutic Drug Monitoring. 13: 120-125. PMID 2053118 DOI: 10.1097/00007691-199103000-00006 |
0.307 |
|
| 1991 |
Browne TR, Mattson RH, Penry JK, Smith DB, Treiman DM, Wilder BJ, Ben-Menachem E, McBride RG, Sherry KM. Multicenter long‐term safety and efficacy study of vigabatrin for refractory complex partial seizures An update Neurology. 41: 363-363. PMID 2006001 DOI: 10.1212/Wnl.41.3.363 |
0.379 |
|
| 1991 |
Schumacher GE, Barr JT, Browne TR, Collins JF. Test performance characteristics of the serum phenytoin concentration (SPC): the relationship between SPC and patient response. The Veterans Administration Epilepsy Cooperative Study Group. Therapeutic Drug Monitoring. 13: 318-324. PMID 1780964 DOI: 10.1097/00007691-199107000-00007 |
0.337 |
|
| 1990 |
Browne TR, Greenblatt DJ, Schumacher GE, Szabo GK, Evans JE, Evans BA. New pharmacokinetic methods. III. Two simple test for "deep pool effect". The Journal of Clinical Pharmacology. 30: 680-685. PMID 2401747 DOI: 10.1002/J.1552-4604.1990.Tb03626.X |
0.455 |
|
| 1990 |
Browne TR, Szabo GK, Walsh CT, Schumacher GE, Evans JE, Evans BA. New pharmacokinetic methods. II: Determination of the presence or absence of product inhibition in drugs with nonlinear pharmacokinetics. Journal of Clinical Pharmacology. 30: 578-84. PMID 2391390 DOI: 10.1002/J.1552-4604.1990.Tb01859.X |
0.386 |
|
| 1990 |
Browne TR, Greenblatt DJ, Szabo GK, Evans JE, Evans BA. New pharmacokinetic methods: I. Estimation of mean serum concentration from trough serum concentration Journal of Clinical Pharmacology. 30: 482-488. PMID 2355100 DOI: 10.1002/J.1552-4604.1990.Tb03612.X |
0.314 |
|
| 1990 |
Nuwer MR, Browne TR, Dodson WE, Dreifuss FE, Engel J, Leppik IE, Mattson RH, Penry J, Treiman DM, Wilder BJ. Generic substitutions for antiepileptic drugs. Neurology. 40: 1647-51. PMID 2234419 DOI: 10.1212/Wnl.40.11.1647 |
0.401 |
|
| 1990 |
Browne TR. Stable isotopes in clinical pharmacokinetic investigations. Advantages and disadvantages. Clinical Pharmacokinectics. 18: 423-433. PMID 2191819 DOI: 10.2165/00003088-199018060-00001 |
0.306 |
|
| 1990 |
Szabo GK, Pylilo RJ, Davoudi H, Browne TR. Simultaneous determination of p-hydroxylated and dihydrodiol metabolites of phenytoin in urine by high-performance liquid chromatography. Journal of Chromatography. 535: 279-85. PMID 2089057 DOI: 10.1016/S0021-9673(01)88953-6 |
0.347 |
|
| 1989 |
Mikati MA, Browne TR, Collins JF, Cramer J, Crill WE, Delgado-Escueta AV, Homan RW, Lubozynski MF, Mattson RH, Mayersdorf A, McCutchen CB, McNamara JO, Rosenthal P, Smith DB, Treiman DM, et al. Time course of carbamazepine autoinduction Neurology. 39: 592-594. PMID 2927687 DOI: 10.1212/Wnl.39.4.592 |
0.36 |
|
| 1989 |
Browne TR, Davoudi H, Donn KH, Dougherty CL, Dukes GE, Evans B, Evans JE, Jamerson B, Kres J, McEntegart CM. Bioavailability of ACC-9653 (phenytoin prodrug). Epilepsia. 30: S27-32. PMID 2670536 DOI: 10.1111/J.1528-1157.1989.Tb05822.X |
0.4 |
|
| 1988 |
Browne TR, Szabo GK, Evans JE, Evans BA, Greenblatt DJ, Mikati MA. Carbamazepine increases phenytoin serum concentration and reduces phenytoin clearance. Neurology. 38: 1146-1146. PMID 3386835 DOI: 10.1212/Wnl.38.7.1146 |
0.403 |
|
| 1988 |
Browne TR, Szabo GK, Evans J, Evans BA, Greenblatt DJ, Mikati MA. Phenobarbital does not alter phenytoin steady-state serum concentration or pharmacokinetics. Neurology. 38: 639-639. PMID 3352926 DOI: 10.1212/Wnl.38.4.639 |
0.374 |
|
| 1988 |
Mikati MA, Browne TR. Comparative efficacy of antiepileptic drugs Clinical Neuropharmacology. 11: 130-140. PMID 3288338 DOI: 10.1097/00002826-198804000-00004 |
0.42 |
|
| 1988 |
Browne TR, Szabo GK, Evans JE, Evans BA, Greenblatt DJ, Schumacher GE. Studies of non-linear pharmacokinetics with stable isotope labeled phenytoin International Journal of Radiation Applications and Instrumentation. Part a. Applied Radiation and Isotopes. 39: 522. DOI: 10.1016/0883-2889(88)90226-2 |
0.324 |
|
| 1987 |
Browne TR, Mattson RH, Penry JK, Smith DB, Treiman DM, Wilder BJ, Ben-Menachem E, Napoliello MJ, Sherry KM, Szabo GK. Vigabatrin for refractory complex partial seizures Multicenter single‐blind study with long‐term follow‐up Neurology. 37: 184-184. PMID 3808298 DOI: 10.1212/Wnl.37.2.184 |
0.371 |
|
| 1987 |
Browne TR, Greenblatt D, Evans JE, Evans BA, Szabo GK, Schumacher GE. Determination of the in Vivo Km and Vmax of a Drug With Tracer Studies The Journal of Clinical Pharmacology. 27: 321-324. PMID 3680591 DOI: 10.1002/J.1552-4604.1987.Tb03023.X |
0.437 |
|
| 1987 |
Browne TR, Greenblatt DJ, Evans JE, Szabo GK, Evans BA, Schumacher GE. Estimation of the elimination half-life of a drug at any serum concentration when the Km and Vmax of the drug are known: calculations and validation with phenytoin The Journal of Clinical Pharmacology. 27: 318-320. PMID 3680590 DOI: 10.1002/J.1552-4604.1987.Tb03022.X |
0.425 |
|
| 1986 |
Browne TR, Greenblatt DJ, Evans JE, Szabo GK, Evans BA, Schumacher GE. Pharmacokinetics: Dose‐Dependent Changes The Journal of Clinical Pharmacology. 26: 463-468. PMID 3734138 DOI: 10.1002/J.1552-4604.1986.Tb03559.X |
0.454 |
|
| 1986 |
Browne TR. Stable Isotopes in Pharmacology Studies: Present and Future The Journal of Clinical Pharmacology. 26: 485-489. PMID 3525614 DOI: 10.1002/J.1552-4604.1986.Tb03563.X |
0.421 |
|
| 1985 |
Evans JE, Browne TR, Kasdon DL, Szabo GK, Evans BA, Greenblatt DJ. Staggered stable isotope administration technique for study of drug distribution. The Journal of Clinical Pharmacology. 25: 309-312. PMID 4008678 DOI: 10.1002/J.1552-4604.1985.Tb02846.X |
0.428 |
|
| 1985 |
Browne TR, Greenblatt DJ, Harmatz JS, Evans JE, Szabo GK, Evans BA, Schumacher GE. Studies with stable isotopes III: Pharmacokinetics of tracer doses of drug. The Journal of Clinical Pharmacology. 25: 59-63. PMID 3973065 DOI: 10.1002/J.1552-4604.1985.Tb02801.X |
0.418 |
|
| 1985 |
Browne TR, Evans JE, Szabo GK, Greenblatt DJ. Studies with stable isotopes II: Phenobarbital pharmacokinetics during monotherapy Journal of Clinical Pharmacology. 25: 51-58. PMID 3973064 DOI: 10.1002/J.1552-4604.1985.Tb02800.X |
0.398 |
|
| 1985 |
Browne TR, Evans JE, Szabo GK, Evans BA, Greenblatt DJ, Schumacher GE. Studies with stable isotopes I: Changes in phenytoin pharmacokinetics and biotransformation during monotherapy. The Journal of Clinical Pharmacology. 25: 43-50. PMID 3973063 DOI: 10.1002/J.1552-4604.1985.Tb02799.X |
0.387 |
|
| 1984 |
Browne TR, Van Langenhove A, Costello CE, Biemann K, Greenblatt DJ. Applications of stable isotope methods to studying the clinical pharmacology of antiepileptic drugs in newborns, infants, children, and adolescents. Therapeutic Drug Monitoring. 6: 3-9. PMID 6369643 DOI: 10.1097/00007691-198403000-00002 |
0.323 |
|
| 1983 |
Cramer JA, Smith DB, Mattson RH, Escueta AVD, Collins JF, Browne TR, Crill WE, Homan RW, Mayersdorf A, McCutchen CB, McNamara JO, Rosenthal NP, Treiman DM, Wilder BJ, Williamson PD. A method of quantification for the evaluation of antiepileptic drug therapy Neurology. 33: 26-37. PMID 6681889 DOI: 10.1212/Wnl.33.3_Suppl_1.26 |
0.431 |
|
| 1983 |
Mattson RH, Cramer JA, Escueta AVD, Smith DB, Collins JF, Browne TR, Crill WE, Homan RW, Mayersdorf A, McCutchen CB, McNamara JO, Rosenthal NP, Treiman DM, Wilder BJ, Williamson PD, et al. A design for the prospective evaluation of the efficacy and toxicity of antiepileptic drugs in adults Neurology. 33: 14-25. PMID 6681888 DOI: 10.1212/Wnl.33.3_Suppl_1.14 |
0.433 |
|
| 1983 |
Browne TR, Feldman RG, Buchanan RA, Allen NC, Fawcett-Vickers L, Szabo GK, Mattson GF, Norman SE, Greenblatt DJ. Methsuximide for complex partial seizures: efficacy, toxicity, clinical pharmacology, and drug interactions. Neurology. 33: 414-8. PMID 6403891 DOI: 10.1212/Wnl.33.4.414 |
0.592 |
|
| 1982 |
Van Langenhove A, Biller JE, Biemann K, Browne TR. Simultaneous determination of phenobarbital and p-hydroxyphenobarbital and their stable isotope labeled analogs by gas chromatography mass spectrometry. Biomedical Mass Spectrometry. 9: 201-7. PMID 7093441 DOI: 10.1002/Bms.1200090505 |
0.366 |
|
| 1981 |
Browne TR, Van Langenhove A, Costello CE, Biemann K, Greenblatt DJ. Kinetic equivalence of stable-isotope-labeled and unlabeled phenytoin Clinical Pharmacology and Therapeutics. 29: 511-515. PMID 7471618 DOI: 10.1038/Clpt.1981.71 |
0.462 |
|
| 1981 |
Van Langenhove A, Costello CE, Biller JE, Biemann K, Browne TR. A gas chromatographic/mass spectrometric method for the simultaneous quantitation of 5,5-diphenylhydantoin (phenytoin), its para-hydroxylated metabolite and their stable isotope labelled analogs Clinica Chimica Acta. 115: 263-275. PMID 7028323 DOI: 10.1016/0009-8981(81)90240-0 |
0.357 |
|
| 1980 |
van Langenhove A, Costello CE, Biller JE, Biemann K, Browne TR. A mass spectrometric method for the determination of stable isotope labeled phenytoin suitable for pulse dosing studies Biomedical Mass Spectrometry. 7: 576-581. PMID 7013848 DOI: 10.1002/Bms.1200071126 |
0.464 |
|
| 1978 |
Browne TR. Drug therapy reviews: clinical pharmacology of antiepileptic drugs. American Journal of Health-System Pharmacy. 35: 1048-1056. DOI: 10.1093/Ajhp/35.9.1048 |
0.471 |
|
| 1978 |
Browne TR. Drug therapy reviews: drug therapy of status epilepticus American Journal of Health-System Pharmacy. 35: 915-922. DOI: 10.1093/Ajhp/35.8.915 |
0.414 |
|
| 1975 |
Browne TR, Dreifuss FE, Dyken PR, Goode DJ, Penry JK, Porter RJ, White BG, White PT. Ethosuximide in the treatment of absence (petit mal) seizures Neurology. 25: 515-515. PMID 805382 DOI: 10.1212/Wnl.25.6.515 |
0.427 |
|
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