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Michael B. Keough, MD PhD - Publications

Affiliations: 
2006-2010 Neuroscience Memorial University of Newfoundland, St. John's, Newfoundland and Labrador, Canada 
 2010-2018 Clinical Neurosciences University of Calgary, Calgary, Alberta, Canada 
 2018-2024 Neurosurgery University of Alberta, Edmonton, Alberta, Canada 
 2021-2021 Neurology Stanford University, Palo Alto, CA 
Area:
neuroplasticity, stroke rehabilitation, remyelination, chondroitin sulfate proteoglycans, glioma
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26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Drexler R, Khatri R, Sauvigny T, Mohme M, Maire CL, Ryba A, Zghaibeh Y, Dührsen L, Salviano-Silva A, Lamszus K, Westphal M, Gempt J, Wefers AK, Neumann JE, Bode H, ... ... Keough MB, et al. A prognostic neural epigenetic signature in high-grade glioma. Nature Medicine. PMID 38760585 DOI: 10.1038/s41591-024-02969-w  0.543
2023 Taylor KR, Barron T, Hui A, Spitzer A, Yalçin B, Ivec AE, Geraghty AC, Hartmann GG, Arzt M, Gillespie SM, Kim YS, Maleki Jahan S, Zhang H, Shamardani K, Su M, ... ... Keough MB, et al. Glioma synapses recruit mechanisms of adaptive plasticity. Nature. PMID 37914930 DOI: 10.1038/s41586-023-06678-1  0.626
2023 Drexler R, Khatri R, Sauvigny T, Mohme M, Maire CL, Ryba A, Zghaibeh Y, Dührsen L, Salviano-Silva A, Lamszus K, Westphal M, Gempt J, Wefers AK, Neumann J, Bode H, ... ... Keough MB, et al. Epigenetic neural glioblastoma enhances synaptic integration and predicts therapeutic vulnerability. Biorxiv : the Preprint Server For Biology. PMID 37609137 DOI: 10.1101/2023.08.04.552017  0.548
2023 Krishna S, Choudhury A, Keough MB, Seo K, Ni L, Kakaizada S, Lee A, Aabedi A, Popova G, Lipkin B, Cao C, Nava Gonzales C, Sudharshan R, Egladyous A, Almeida N, et al. Glioblastoma remodelling of human neural circuits decreases survival. Nature. PMID 37138086 DOI: 10.1038/s41586-023-06036-1  0.731
2022 Fernández-Castañeda A, Lu P, Geraghty AC, Song E, Lee MH, Wood J, O'Dea MR, Dutton S, Shamardani K, Nwangwu K, Mancusi R, Yalçın B, Taylor KR, Acosta-Alvarez L, Malacon K, ... Keough MB, et al. Mild respiratory COVID can cause multi-lineage neural cell and myelin dysregulation. Cell. PMID 35768006 DOI: 10.1016/j.cell.2022.06.008  0.662
2022 Keough MB, Monje M. Neural Signaling in Cancer. Annual Review of Neuroscience. PMID 35259916 DOI: 10.1146/annurev-neuro-111020-092702  0.503
2020 Rawji KS, Young AMH, Ghosh T, Michaels NJ, Mirzaei R, Kappen J, Kolehmainen KL, Alaeiilkhchi N, Lozinski B, Mishra MK, Pu A, Tang W, Zein S, Kaushik DK, Keough MB, et al. Correction to: Niacin-mediated rejuvenation of macrophage/microglia enhances remyelination of the aging central nervous system. Acta Neuropathologica. PMID 32211925 DOI: 10.1007/S00401-020-02146-6  0.709
2020 Rawji KS, Young AMH, Ghosh T, Michaels NJ, Mirzaei R, Kappen J, Kolehmainen KL, Alaeiilkhchi N, Lozinski B, Mishra MK, Pu A, Tang W, Zein S, Kaushik DK, Keough MB, et al. Niacin-mediated rejuvenation of macrophage/microglia enhances remyelination of the aging central nervous system. Acta Neuropathologica. PMID 32030468 DOI: 10.1007/S00401-020-02129-7  0.758
2019 Stephenson EL, Zhang P, Ghorbani S, Wang A, Gu J, Keough MB, Rawji KS, Silva C, Yong VW, Ling CC. Targeting the Chondroitin Sulfate Proteoglycans: Evaluating Fluorinated Glucosamines and Xylosides in Screens Pertinent to Multiple Sclerosis. Acs Central Science. 5: 1223-1234. PMID 31404231 DOI: 10.1021/Acscentsci.9B00327  0.541
2018 Jensen SK, Michaels NJ, Ilyntskyy S, Keough MB, Kovalchuk O, Yong VW. Multimodal Enhancement of Remyelination by Exercise with a Pivotal Role for Oligodendroglial PGC1α. Cell Reports. 24: 3167-3179. PMID 30232000 DOI: 10.1016/J.Celrep.2018.08.060  0.547
2017 Plemel JR, Michaels NJ, Weishaupt N, Caprariello AV, Keough MB, Rogers JA, Yukseloglu A, Lim J, Patel VV, Rawji KS, Jensen SK, Teo W, Heyne B, Whitehead SN, Stys PK, et al. Mechanisms of lysophosphatidylcholine-induced demyelination: A primary lipid disrupting myelinopathy. Glia. PMID 29068088 DOI: 10.1002/Glia.23245  0.743
2017 Plemel JR, Caprariello AV, Keough MB, Henry TJ, Tsutsui S, Chu TH, Schenk GJ, Klaver R, Yong VW, Stys PK. Unique spectral signatures of the nucleic acid dye acridine orange can distinguish cell death by apoptosis and necroptosis. The Journal of Cell Biology. PMID 28264914 DOI: 10.1083/Jcb.201602028  0.712
2016 Keough MB, Rogers JA, Zhang P, Jensen SK, Stephenson EL, Chen T, Hurlbert MG, Lau LW, Rawji KS, Plemel JR, Koch M, Ling CC, Yong VW. An inhibitor of chondroitin sulfate proteoglycan synthesis promotes central nervous system remyelination. Nature Communications. 7: 11312. PMID 27115988 DOI: 10.1038/Ncomms11312  0.748
2016 Clemente-Casares X, Blanco J, Ambalavanan P, Yamanouchi J, Singha S, Fandos C, Tsai S, Wang J, Garabatos N, Izquierdo C, Agrawal S, Keough MB, Yong VW, James E, Moore A, et al. Expanding antigen-specific regulatory networks to treat autoimmunity. Nature. PMID 26886799 DOI: 10.1038/Nature16962  0.499
2015 Keough MB, Jensen SK, Yong VW. Experimental demyelination and remyelination of murine spinal cord by focal injection of lysolecithin. Journal of Visualized Experiments : Jove. PMID 25867716 DOI: 10.3791/52679  0.583
2014 Mishra MK, Wang J, Keough MB, Fan Y, Silva C, Sloka S, Hayardeny L, Brück W, Yong VW. Laquinimod reduces neuroaxonal injury through inhibiting microglial activation. Annals of Clinical and Translational Neurology. 1: 409-22. PMID 25356411 DOI: 10.1002/Acn3.67  0.591
2014 Plemel JR, Keough MB, Duncan GJ, Sparling JS, Yong VW, Stys PK, Tetzlaff W. Remyelination after spinal cord injury: is it a target for repair? Progress in Neurobiology. 117: 54-72. PMID 24582777 DOI: 10.1016/J.Pneurobio.2014.02.006  0.741
2014 Mishra M, Rawji K, Keough MB, Fan Y, Yong VW. Enhancement of the activity of M2-polarized macrophages/microglia promotes recovery from demyelination Journal of Neuroimmunology. 275: 187. DOI: 10.1016/J.Jneuroim.2014.08.504  0.501
2014 Stephenson EL, Rogers JA, Keough MB, Yong VW. Changes in chondroitin sulfate proteoglycans in experimental autoimmune encephalomyelitis Journal of Neuroimmunology. 275: 175. DOI: 10.1016/J.Jneuroim.2014.08.470  0.467
2013 Lau LW, Cua R, Keough MB, Haylock-Jacobs S, Yong VW. Pathophysiology of the brain extracellular matrix: a new target for remyelination. Nature Reviews. Neuroscience. 14: 722-9. PMID 23985834 DOI: 10.1038/Nrn3550  0.56
2013 Cua RC, Lau LW, Keough MB, Midha R, Apte SS, Yong VW. Overcoming neurite-inhibitory chondroitin sulfate proteoglycans in the astrocyte matrix. Glia. 61: 972-84. PMID 23554135 DOI: 10.1002/Glia.22489  0.536
2013 Yong VW, Keough M, Lau L. Reply: To PMID 23034914. Annals of Neurology. 73: 316-7. PMID 23424070 DOI: 10.1002/ana.23827  0.341
2013 Keough MB, Yong VW. Remyelination therapy for multiple sclerosis. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 10: 44-54. PMID 23070731 DOI: 10.1007/S13311-012-0152-7  0.562
2012 Lau LW, Keough MB, Haylock-Jacobs S, Cua R, Döring A, Sloka S, Stirling DP, Rivest S, Yong VW. Chondroitin sulfate proteoglycans in demyelinated lesions impair remyelination. Annals of Neurology. 72: 419-32. PMID 23034914 DOI: 10.1002/Ana.23599  0.594
2011 MacLellan CL, Keough MB, Granter-Button S, Chernenko GA, Butt S, Corbett D. A critical threshold of rehabilitation involving brain-derived neurotrophic factor is required for poststroke recovery. Neurorehabilitation and Neural Repair. 25: 740-8. PMID 21705652 DOI: 10.1177/1545968311407517  0.426
2011 Haylock-Jacobs S, Keough MB, Lau L, Yong VW. Chondroitin sulphate proteoglycans: extracellular matrix proteins that regulate immunity of the central nervous system. Autoimmunity Reviews. 10: 766-72. PMID 21664302 DOI: 10.1016/J.Autrev.2011.05.019  0.565
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