Daniel Bertrand - Publications

Center for Neuroscience Centre Médical Universitaire, Switzerland., Genève, Genève, Switzerland 

49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Knoflach F, Hernandez MC, Bertrand D. GABAA receptor-mediated neurotransmission: Not so simple after all. Biochemical Pharmacology. PMID 27002180 DOI: 10.1016/j.bcp.2016.03.014  0.6
2015 Wallace TL, Bertrand D. Neuronal α7 Nicotinic Receptors as a Target for the Treatment of Schizophrenia. International Review of Neurobiology. 124: 79-111. PMID 26472526 DOI: 10.1016/bs.irn.2015.08.003  0.6
2015 Stoiljkovic M, Leventhal L, Chen A, Chen T, Driscoll R, Flood D, Hodgdon H, Hurst R, Nagy D, Piser T, Tang C, Townsend M, Tu Z, Bertrand D, Koenig G, et al. Concentration-response relationship of the α7 nicotinic acetylcholine receptor agonist FRM-17874 across multiple in vitro and in vivo assays. Biochemical Pharmacology. PMID 26206187 DOI: 10.1016/j.bcp.2015.07.006  0.6
2014 Sahdeo S, Wallace T, Hirakawa R, Knoflach F, Bertrand D, Maag H, Misner D, Tombaugh GC, Santarelli L, Brameld K, Milla ME, Button DC. Characterization of RO5126946, a Novel α7 nicotinic acetylcholine receptor-positive allosteric modulator. The Journal of Pharmacology and Experimental Therapeutics. 350: 455-68. PMID 24917542 DOI: 10.1124/jpet.113.210963  0.6
2014 Bürgi JJ, Awale M, Boss SD, Schaer T, Marger F, Viveros-Paredes JM, Bertrand S, Gertsch J, Bertrand D, Reymond JL. Discovery of potent positive allosteric modulators of the α3β2 nicotinic acetylcholine receptor by a chemical space walk in ChEMBL. Acs Chemical Neuroscience. 5: 346-59. PMID 24593915 DOI: 10.1021/cn4002297  0.6
2013 Prestori F, Bonardi C, Mapelli L, Lombardo P, Goselink R, De Stefano ME, Gandolfi D, Mapelli J, Bertrand D, Schonewille M, De Zeeuw C, D'Angelo E. Gating of long-term potentiation by nicotinic acetylcholine receptors at the cerebellum input stage. Plos One. 8: e64828. PMID 23741401 DOI: 10.1371/journal.pone.0064828  0.6
2013 Stornaiuolo M, De Kloe GE, Rucktooa P, Fish A, van Elk R, Edink ES, Bertrand D, Smit AB, de Esch IJ, Sixma TK. Assembly of a π-π stack of ligands in the binding site of an acetylcholine-binding protein. Nature Communications. 4: 1875. PMID 23695669 DOI: 10.1038/ncomms2900  0.6
2013 Dani JA, Donnelly-Roberts D, Bertrand D. Nicotinic acetylcholine receptors as therapeutic targets: emerging frontiers in basic research and clinical science--editorial comments. Biochemical Pharmacology. 86: 1041. PMID 23684691 DOI: 10.1016/j.bcp.2013.05.002  0.6
2013 Spurny R, Billen B, Howard RJ, Brams M, Debaveye S, Price KL, Weston DA, Strelkov SV, Tytgat J, Bertrand S, Bertrand D, Lummis SC, Ulens C. Multisite binding of a general anesthetic to the prokaryotic pentameric Erwinia chrysanthemi ligand-gated ion channel (ELIC). The Journal of Biological Chemistry. 288: 8355-64. PMID 23364792 DOI: 10.1074/jbc.M112.424507  0.6
2013 Wallace TL, Bertrand D. Alpha7 neuronal nicotinic receptors as a drug target in schizophrenia. Expert Opinion On Therapeutic Targets. 17: 139-55. PMID 23231385 DOI: 10.1517/14728222.2013.736498  0.6
2012 Spurny R, Ramerstorfer J, Price K, Brams M, Ernst M, Nury H, Verheij M, Legrand P, Bertrand D, Bertrand S, Dougherty DA, de Esch IJ, Corringer PJ, Sieghart W, Lummis SC, et al. Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines. Proceedings of the National Academy of Sciences of the United States of America. 109: E3028-34. PMID 23035248 DOI: 10.1073/pnas.1208208109  0.6
2012 Billen B, Spurny R, Brams M, van Elk R, Valera-Kummer S, Yakel JL, Voets T, Bertrand D, Smit AB, Ulens C. Molecular actions of smoking cessation drugs at α4β2 nicotinic receptors defined in crystal structures of a homologous binding protein. Proceedings of the National Academy of Sciences of the United States of America. 109: 9173-8. PMID 22619328 DOI: 10.1073/pnas.1116397109  0.6
2012 Utkin YN, Weise C, Kasheverov IE, Andreeva TV, Kryukova EV, Zhmak MN, Starkov VG, Hoang NA, Bertrand D, Ramerstorfer J, Sieghart W, Thompson AJ, Lummis SC, Tsetlin VI. Azemiopsin from Azemiops feae viper venom, a novel polypeptide ligand of nicotinic acetylcholine receptor. The Journal of Biological Chemistry. 287: 27079-86. PMID 22613724 DOI: 10.1074/jbc.M112.363051  0.6
2012 Bréthous L, Garcia-Delgado N, Schwartz J, Bertrand S, Bertrand D, Reymond JL. Synthesis and nicotinic receptor activity of chemical space analogues of N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chlorobenzamide (PNU-282,987) and 1,4-diazabicyclo[3.2.2]nonane-4-carboxylic acid 4-bromophenyl ester (SSR180711). Journal of Medicinal Chemistry. 55: 4605-18. PMID 22591063 DOI: 10.1021/jm300030r  0.6
2012 Favreau P, Benoit E, Hocking HG, Carlier L, D' hoedt D, Leipold E, Markgraf R, Schlumberger S, Córdova MA, Gaertner H, Paolini-Bertrand M, Hartley O, Tytgat J, Heinemann SH, Bertrand D, et al. A novel µ-conopeptide, CnIIIC, exerts potent and preferential inhibition of NaV1.2/1.4 channels and blocks neuronal nicotinic acetylcholine receptors. British Journal of Pharmacology. 166: 1654-68. PMID 22229737 DOI: 10.1111/j.1476-5381.2012.01837.x  0.6
2012 Osipov AV, Rucktooa P, Kasheverov IE, Filkin SY, Starkov VG, Andreeva TV, Sixma TK, Bertrand D, Utkin YN, Tsetlin VI. Dimeric α-cobratoxin X-ray structure: localization of intermolecular disulfides and possible mode of binding to nicotinic acetylcholine receptors. The Journal of Biological Chemistry. 287: 6725-34. PMID 22223648 DOI: 10.1074/jbc.M111.322313  0.6
2012 Prickaerts J, van Goethem NP, Chesworth R, Shapiro G, Boess FG, Methfessel C, Reneerkens OA, Flood DG, Hilt D, Gawryl M, Bertrand S, Bertrand D, König G. EVP-6124, a novel and selective α7 nicotinic acetylcholine receptor partial agonist, improves memory performance by potentiating the acetylcholine response of α7 nicotinic acetylcholine receptors. Neuropharmacology. 62: 1099-110. PMID 22085888 DOI: 10.1016/j.neuropharm.2011.10.024  0.6
2012 Murray TA, Bertrand D, Papke RL, George AA, Pantoja R, Srinivasan R, Liu Q, Wu J, Whiteaker P, Lester HA, Lukas RJ. α7β2 nicotinic acetylcholine receptors assemble, function, and are activated primarily via their α7-α7 interfaces. Molecular Pharmacology. 81: 175-88. PMID 22039094 DOI: 10.1124/mol.111.074088  0.6
2012 Steinlein OK, Hoda JC, Bertrand S, Bertrand D. Mutations in familial nocturnal frontal lobe epilepsy might be associated with distinct neurological phenotypes. Seizure. 21: 118-23. PMID 22036597 DOI: 10.1016/j.seizure.2011.10.003  0.6
2011 Blum LC, van Deursen R, Bertrand S, Mayer M, Bürgi JJ, Bertrand D, Reymond JL. Discovery of α7-nicotinic receptor ligands by virtual screening of the chemical universe database GDB-13. Journal of Chemical Information and Modeling. 51: 3105-12. PMID 22077916 DOI: 10.1021/ci200410u  0.6
2011 Akdemir A, Rucktooa P, Jongejan A, Elk Rv, Bertrand S, Sixma TK, Bertrand D, Smit AB, Leurs R, de Graaf C, de Esch IJ. Acetylcholine binding protein (AChBP) as template for hierarchical in silico screening procedures to identify structurally novel ligands for the nicotinic receptors. Bioorganic & Medicinal Chemistry. 19: 6107-19. PMID 21920761 DOI: 10.1016/j.bmc.2011.08.028  0.6
2011 Pucci L, Grazioso G, Dallanoce C, Rizzi L, De Micheli C, Clementi F, Bertrand S, Bertrand D, Longhi R, De Amici M, Gotti C. Engineering of α-conotoxin MII-derived peptides with increased selectivity for native α6β2* nicotinic acetylcholine receptors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 3775-89. PMID 21778325 DOI: 10.1096/fj.10-179853  0.6
2011 Lyukmanova EN, Shenkarev ZO, Shulepko MA, Mineev KS, D'Hoedt D, Kasheverov IE, Filkin SY, Krivolapova AP, Janickova H, Dolezal V, Dolgikh DA, Arseniev AS, Bertrand D, Tsetlin VI, Kirpichnikov MP. NMR structure and action on nicotinic acetylcholine receptors of water-soluble domain of human LYNX1. The Journal of Biological Chemistry. 286: 10618-27. PMID 21252236 DOI: 10.1074/jbc.M110.189100  0.6
2010 Garcia-Delgado N, Bertrand S, Nguyen KT, van Deursen R, Bertrand D, Reymond JL. Exploring α7-Nicotinic Receptor Ligand Diversity by Scaffold Enumeration from the Chemical Universe Database GDB. Acs Medicinal Chemistry Letters. 1: 422-6. PMID 24900227 DOI: 10.1021/ml100125f  0.6
2010 Bertrand D, Bertrand S, Neveu E, Fernandes P. Molecular characterization of off-target activities of telithromycin: a potential role for nicotinic acetylcholine receptors. Antimicrobial Agents and Chemotherapy. 54: 5399-402. PMID 20855733 DOI: 10.1128/AAC.00840-10  0.6
2010 Araud T, Wonnacott S, Bertrand D. Associated proteins: The universal toolbox controlling ligand gated ion channel function Biochemical Pharmacology. 80: 160-169. PMID 20346921 DOI: 10.1016/j.bcp.2010.03.017  0.6
2010 Roy A, Zhou X, Chong MZ, D'hoedt D, Foo CS, Rajagopalan N, Nirthanan S, Bertrand D, Sivaraman J, Kini RM. Structural and functional characterization of a novel homodimeric three-finger neurotoxin from the venom of Ophiophagus hannah (king cobra). The Journal of Biological Chemistry. 285: 8302-15. PMID 20071329 DOI: 10.1074/jbc.M109.074161  0.6
2009 Kasheverov IE, Zhmak MN, Fish A, Rucktooa P, Khruschov AY, Osipov AV, Ziganshin RH, D'hoedt D, Bertrand D, Sixma TK, Smit AB, Tsetlin VI. Interaction of alpha-conotoxin ImII and its analogs with nicotinic receptors and acetylcholine-binding proteins: additional binding sites on Torpedo receptor. Journal of Neurochemistry. 111: 934-44. PMID 19712060 DOI: 10.1111/j.1471-4159.2009.06359.x  0.6
2009 Bertrand D, Gopalakrishnan M, Donnelly-Roberts D. Nicotinic Acetylcholine Receptors as Therapeutic Targets: Emerging Frontiers in Basic Research and Clinical Science-Editorial Perspective Biochemical Pharmacology. 78: 657. PMID 19576180 DOI: 10.1016/j.bcp.2009.06.101  0.6
2009 Ulens C, Akdemir A, Jongejan A, van Elk R, Bertrand S, Perrakis A, Leurs R, Smit AB, Sixma TK, Bertrand D, de Esch IJ. Use of acetylcholine binding protein in the search for novel alpha7 nicotinic receptor ligands. In silico docking, pharmacological screening, and X-ray analysis. Journal of Medicinal Chemistry. 52: 2372-83. PMID 19331415 DOI: 10.1021/jm801400g  0.6
2008 Osipov AV, Kasheverov IE, Makarova YV, Starkov VG, Vorontsova OV, Ziganshin RKh, Andreeva TV, Serebryakova MV, Benoit A, Hogg RC, Bertrand D, Tsetlin VI, Utkin YN. Naturally occurring disulfide-bound dimers of three-fingered toxins: a paradigm for biological activity diversification. The Journal of Biological Chemistry. 283: 14571-80. PMID 18381281 DOI: 10.1074/jbc.M802085200  0.6
2008 Walsh H, Govind AP, Mastro R, Hoda JC, Bertrand D, Vallejo Y, Green WN. Up-regulation of nicotinic receptors by nicotine varies with receptor subtype. The Journal of Biological Chemistry. 283: 6022-32. PMID 18174175 DOI: 10.1074/jbc.M703432200  0.6
2007 Gopalakrishnan M, Bertrand D, Williams M. Nicotinic acetylcholine receptors as therapeutic targets: emerging frontiers in basic research and clinical science - Editorial comments Biochemical Pharmacology. 74: 1091. PMID 17889037 DOI: 10.1016/j.bcp.2007.09.007  0.6
2007 Bertrand D, Gopalakrishnan M. Allosteric modulation of nicotinic acetylcholine receptors Biochemical Pharmacology. 74: 1155-1163. PMID 17707779 DOI: 10.1016/j.bcp.2007.07.011  0.6
2007 Lyukmanova EN, Shenkarev ZO, Schulga AA, Ermolyuk YS, Mordvintsev DY, Utkin YN, Shoulepko MA, Hogg RC, Bertrand D, Dolgikh DA, Tsetlin VI, Kirpichnikov MP. Bacterial expression, NMR, and electrophysiology analysis of chimeric short/long-chain alpha-neurotoxins acting on neuronal nicotinic receptors. The Journal of Biological Chemistry. 282: 24784-91. PMID 17576769 DOI: 10.1074/jbc.M611263200  0.6
2007 Zoffmann S, Bertrand S, Do QT, Bertrand D, Rognan D, Hibert M, Galzi JL. Topological analysis of the complex formed between neurokinin A and the NK2 tachykinin receptor. Journal of Neurochemistry. 101: 506-16. PMID 17402972 DOI: 10.1111/j.1471-4159.2007.04473.x  0.6
2007 Grandl J, Sakr E, Kotzyba-Hibert F, Krieger F, Bertrand S, Bertrand D, Vogel H, Goeldner M, Hovius R. Fluorescent epibatidine agonists for neuronal and muscle-type nicotinic acetylcholine receptors. Angewandte Chemie (International Ed. in English). 46: 3505-8. PMID 17385777 DOI: 10.1002/anie.200604807  0.6
2007 Dani JA, Bertrand D. Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system. Annual Review of Pharmacology and Toxicology. 47: 699-729. PMID 17009926 DOI: 10.1146/annurev.pharmtox.47.120505.105214  0.6
2006 Tsetlin VI, Kasheverov IE, Zhmak MN, Utkin YN, Vulfius CA, Smit AB, Bertrand D. Alpha-conotoxin analogs with enhanced affinity for nicotinic receptors and acetylcholine-binding proteins. Journal of Molecular Neuroscience : Mn. 30: 77-8. PMID 17192636 DOI: 10.1385/JMN:30:1:77  0.6
2006 Sakr E, Kotzyba-Hibert F, Grande J, Hovius R, Vogel H, Bertrand S, Bertrand D, Goeldner M. Engineered site-directed labeling of nicotinic acetylcholine receptors using reactive epibatidine derivatives: appraisal of epibatidine-docking models in neuronal and muscular receptors. Journal of Molecular Neuroscience : Mn. 30: 35-6. PMID 17192618 DOI: 10.1385/JMN:30:1:35  0.6
2006 Mourot A, Rodrigo J, Bertrand S, Bertrand D, Goeldner M, Kotzyba-Hibert F. Reorganization of the nicotinic acetylcholine receptor during desensitization probed with a photoactivatable agonist. Journal of Molecular Neuroscience : Mn. 30: 13-4. PMID 17192607 DOI: 10.1385/JMN:30:1:13  0.6
2006 Smit AB, Celie PH, Kasheverov IE, Mordvintsev DY, van Nierop P, Bertrand D, Tsetlin V, Sixma TK. Acetylcholine-binding proteins: functional and structural homologs of nicotinic acetylcholine receptors. Journal of Molecular Neuroscience : Mn. 30: 9-10. PMID 17192605 DOI: 10.1385/JMN:30:1:9  0.6
2006 Ulens C, Hogg RC, Celie PH, Bertrand D, Tsetlin V, Smit AB, Sixma TK. Structural determinants of selective alpha-conotoxin binding to a nicotinic acetylcholine receptor homolog AChBP. Proceedings of the National Academy of Sciences of the United States of America. 103: 3615-20. PMID 16505382 DOI: 10.1073/pnas.0507889103  0.6
2006 van Nierop P, Bertrand S, Munno DW, Gouwenberg Y, van Minnen J, Spafford JD, Syed NI, Bertrand D, Smit AB. Identification and functional expression of a family of nicotinic acetylcholine receptor subunits in the central nervous system of the mollusc Lymnaea stagnalis. The Journal of Biological Chemistry. 281: 1680-91. PMID 16286458 DOI: 10.1074/jbc.M508571200  0.6
2006 Mourot A, Rodrigo J, Kotzyba-Hibert F, Bertrand S, Bertrand D, Goeldner M. Probing the reorganization of the nicotinic acetylcholine receptor during desensitization by time-resolved covalent labeling using [3H]AC5, a photoactivatable agonist. Molecular Pharmacology. 69: 452-61. PMID 16269537 DOI: 10.1124/mol.105.017566  0.6
2005 Celie PH, Kasheverov IE, Mordvintsev DY, Hogg RC, van Nierop P, van Elk R, van Rossum-Fikkert SE, Zhmak MN, Bertrand D, Tsetlin V, Sixma TK, Smit AB. Crystal structure of nicotinic acetylcholine receptor homolog AChBP in complex with an alpha-conotoxin PnIA variant. Nature Structural & Molecular Biology. 12: 582-8. PMID 15951818 DOI: 10.1038/nsmb951  0.6
2005 Vallejo YF, Buisson B, Bertrand D, Green WN. Chronic nicotine exposure upregulates nicotinic receptors by a novel mechanism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 5563-72. PMID 15944384 DOI: 10.1523/JNEUROSCI.5240-04.2005  0.6
2005 Hurst RS, Hajós M, Raggenbass M, Wall TM, Higdon NR, Lawson JA, Rutherford-Root KL, Berkenpas MB, Hoffmann WE, Piotrowski DW, Groppi VE, Allaman G, Ogier R, Bertrand S, Bertrand D, et al. A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 4396-405. PMID 15858066 DOI: 10.1523/JNEUROSCI.5269-04.2005  0.6
2004 Itier V, Schönbächler R, Tribollet E, Honer M, Prinz K, Marguerat A, Bertrand S, Bunnelle WH, Schubiger PA, Meyer MD, Sullivan JP, Bertrand D, Westera G. A-186253, a specific antagonist of the alpha 4 beta 2 nAChRs: its properties and potential to study brain nicotinic acetylcholine receptors. Neuropharmacology. 47: 538-57. PMID 15380372 DOI: 10.1016/j.neuropharm.2004.05.006  0.6
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