| Year |
Citation |
Score |
| 2021 |
Struyfs C, Cammue BPA, Thevissen K. Membrane-Interacting Antifungal Peptides. Frontiers in Cell and Developmental Biology. 9: 649875. PMID 33912564 DOI: 10.3389/fcell.2021.649875 |
0.308 |
|
| 2020 |
Tits J, Cools F, De Cremer K, De Brucker K, Berman J, Verbruggen K, Gevaert B, Cos P, Cammue BPA, Thevissen K. Combination of miconazole and domiphen bromide is fungicidal against biofilms of resistant spp. Antimicrobial Agents and Chemotherapy. PMID 32690639 DOI: 10.1128/Aac.01296-20 |
0.342 |
|
| 2020 |
Struyfs C, Cools TL, De Cremer K, Sampaio-Marques B, Ludovico P, Wasko BM, Kaeberlein M, Cammue BPA, Thevissen K. The antifungal plant defensin HsAFP1 induces autophagy, vacuolar dysfunction and cell cycle impairment in yeast. Biochimica Et Biophysica Acta. Biomembranes. 1862: 183255. PMID 32145284 DOI: 10.1016/J.Bbamem.2020.183255 |
0.418 |
|
| 2018 |
Winderickx S, De Brucker K, Bird MJ, Windmolders P, Meert E, Cammue BPA, Thevissen K. Structure-activity relationship study of the antimicrobial CRAMP-derived peptide CRAMP20-33. Peptides. 109: 33-38. PMID 30176261 DOI: 10.1016/J.Peptides.2018.08.013 |
0.342 |
|
| 2018 |
Dijck PV, Sjollema J, Cammue BP, Lagrou K, Berman J, d'Enfert C, Andes DR, Arendrup MC, Brakhage AA, Calderone R, Cantón E, Coenye T, Cos P, Cowen LE, Edgerton M, ... ... Thevissen K, et al. Methodologies for and evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms. Microbial Cell (Graz, Austria). 5: 300-326. PMID 29992128 DOI: 10.15698/Mic2018.07.638 |
0.315 |
|
| 2018 |
Yeaman MR, Büttner S, Thevissen K. Regulated Cell Death as a Therapeutic Target for Novel Antifungal Peptides and Biologics. Oxidative Medicine and Cellular Longevity. 2018: 5473817. PMID 29854086 DOI: 10.1155/2018/5473817 |
0.397 |
|
| 2017 |
Cools TL, Vriens K, Struyfs C, Verbandt S, Ramada MHS, Brand GD, Bloch C, Koch B, Traven A, Drijfhout JW, Demuyser L, Kucharíková S, Van Dijck P, Spasic D, Lammertyn J, ... ... Thevissen K, et al. The Antifungal Plant Defensin HsAFP1 Is a Phosphatidic Acid-Interacting Peptide Inducing Membrane Permeabilization. Frontiers in Microbiology. 8: 2295. PMID 29209301 DOI: 10.3389/Fmicb.2017.02295 |
0.445 |
|
| 2017 |
Cools TL, Struyfs C, Drijfhout JW, Kucharíková S, Lobo Romero C, Van Dijck P, Ramada MHS, Bloch C, Cammue BPA, Thevissen K. A Linear 19-Mer Plant Defensin-Derived Peptide Acts Synergistically with Caspofungin against Biofilms. Frontiers in Microbiology. 8: 2051. PMID 29104569 DOI: 10.3389/Fmicb.2017.02051 |
0.435 |
|
| 2017 |
De Coninck B, Verheesen P, Vos CM, Van Daele I, De Bolle MF, Vieira JV, Peferoen M, Cammue BPA, Thevissen K. Fungal Glucosylceramide-Specific Camelid Single Domain Antibodies Are Characterized by Broad Spectrum Antifungal Activity. Frontiers in Microbiology. 8: 1059. PMID 28659884 DOI: 10.3389/Fmicb.2017.01059 |
0.405 |
|
| 2017 |
Cools TL, Struyfs C, Cammue BP, Thevissen K. Antifungal plant defensins: increased insight in their mode of action as a basis for their use to combat fungal infections. Future Microbiology. 12: 441-454. PMID 28339295 DOI: 10.2217/Fmb-2016-0181 |
0.477 |
|
| 2017 |
Gerits E, Van der Massen I, Vandamme K, De Cremer K, De Brucker K, Thevissen K, Cammue BPA, Beullens S, Fauvart M, Verstraeten N, Michiels J, Roberts M. In vitro activity of the antiasthmatic drug zafirlukast against the oral pathogens Porphyromonas gingivalis and Streptococcus mutans. Fems Microbiology Letters. 364. PMID 28087617 DOI: 10.1093/Femsle/Fnx005 |
0.318 |
|
| 2017 |
Gerits E, Defraine V, Vandamme K, De Cremer K, De Brucker K, Thevissen K, Cammue BP, Beullens S, Fauvart M, Verstraeten N, Michiels J. Repurposing Toremifene for Treatment of Oral Bacterial Infections. Antimicrobial Agents and Chemotherapy. 61. PMID 27993858 DOI: 10.1128/Aac.01846-16 |
0.358 |
|
| 2017 |
Delattin N, Brucker K, Cremer K, Cammue BP, Thevissen K. Antimicrobial Peptides as a Strategy to Combat Fungal Biofilms. Current Topics in Medicinal Chemistry. 17: 604-612. PMID 27411323 DOI: 10.2174/1568026616666160713142228 |
0.382 |
|
| 2017 |
Verbandt S, Cammue BPA, Thevissen K. Yeast as a model for the identification of novel survival-promoting compounds applicable to treat degenerative diseases. Mechanisms of Ageing and Development. 161: 306-316. PMID 27287065 DOI: 10.1016/J.Mad.2016.06.003 |
0.302 |
|
| 2016 |
Moreels L, Peigneur S, Yamaguchi Y, Vriens K, Waelkens E, Zhu S, Thevissen K, Cammue BP, Sato K, Tytgat J. Expanding the pharmacological profile of κ-hefutoxin 1 and analogues: a focus on the inhibitory effect on the oncogenic channel Kv10.1. Peptides. PMID 27578329 DOI: 10.1016/J.Peptides.2016.08.008 |
0.38 |
|
| 2016 |
Vriens K, Peigneur S, De Coninck B, Tytgat J, Cammue BP, Thevissen K. The antifungal plant defensin AtPDF2.3 from Arabidopsis thaliana blocks potassium channels. Scientific Reports. 6: 32121. PMID 27573545 DOI: 10.1038/Srep32121 |
0.329 |
|
| 2016 |
Peeters E, Hooyberghs G, Robijns S, Waldrant K, De Weerdt A, Delattin N, Liebens V, Kucharíková S, Tournu H, Verstraeten N, Dovgan B, Girandon L, Fröhlich M, De Brucker K, Van Dijck P, ... ... Thevissen K, et al. Modulation of the Substitution Pattern of 5-Aryl-2-Aminoimidazoles Allows Fine-Tuning of Their Antibiofilm Activity Spectrum and Toxicity. Antimicrobial Agents and Chemotherapy. 60: 6483-6497. PMID 27550355 DOI: 10.1128/Aac.00035-16 |
0.335 |
|
| 2016 |
Verbandt S, Henriques ST, Spincemaille P, Harvey PJ, Chandhok G, Sauer V, Coninck B, Cassiman D, Craik DJ, Cammue BP, Cremer K, Thevissen K. Identification of survival-promoting OSIP108 peptide variants and their internalization in human cells. Mechanisms of Ageing and Development. PMID 27491841 DOI: 10.1016/J.Mad.2016.07.013 |
0.391 |
|
| 2016 |
De Cremer K, De Brucker K, Staes I, Peeters A, Van den Driessche F, Coenye T, Cammue BP, Thevissen K. Stimulation of superoxide production increases fungicidal action of miconazole against Candida albicans biofilms. Scientific Reports. 6: 27463. PMID 27272719 DOI: 10.1038/Srep27463 |
0.377 |
|
| 2016 |
Pucca MB, Cerni FA, Pinheiro-Junior EL, Zoccal KF, Bordon KCF, Amorim FG, Peigneur S, Vriens K, Thevissen K, Cammue BPA, Júnior RBM, Arruda E, Faccioli LH, Tytgat J, Arantes EC. Non-disulfide-bridged peptides from Tityus serrulatus venom: Evidence for proline-free ACE-inhibitors. Peptides. 82: 44-51. PMID 27221550 DOI: 10.1016/J.Peptides.2016.05.008 |
0.344 |
|
| 2016 |
Gerits E, Blommaert E, Lippell A, O'Neill AJ, Weytjens B, De Maeyer D, Fierro AC, Marchal K, Marchand A, Chaltin P, Spincemaille P, De Brucker K, Thevissen K, Cammue BP, Swings T, et al. Elucidation of the Mode of Action of a New Antibacterial Compound Active against Staphylococcus aureus and Pseudomonas aeruginosa. Plos One. 11: e0155139. PMID 27167126 DOI: 10.1371/Journal.Pone.0155139 |
0.397 |
|
| 2016 |
De Brucker K, De Cremer K, Cammue BP, Thevissen K. Protocol for Determination of the Persister Subpopulation in Candida Albicans Biofilms. Methods in Molecular Biology (Clifton, N.J.). 1333: 67-72. PMID 26468100 DOI: 10.1007/978-1-4939-2854-5_6 |
0.325 |
|
| 2015 |
Vriens K, Cools TL, Harvey PJ, Craik DJ, Braem A, Vleugels J, Coninck B, Cammue BP, Thevissen K. The radish defensins RsAFP1 and RsAFP2 act synergistically with caspofungin against Candida albicans biofilms. Peptides. PMID 26592804 DOI: 10.1016/J.Peptides.2015.11.001 |
0.419 |
|
| 2015 |
Vriens K, Cools TL, Harvey PJ, Craik DJ, Spincemaille P, Cassiman D, Braem A, Vleugels J, Nibbering PH, Drijfhout JW, De Coninck B, Cammue BP, Thevissen K. Synergistic Activity of the Plant Defensin HsAFP1 and Caspofungin against Candida albicans Biofilms and Planktonic Cultures. Plos One. 10: e0132701. PMID 26248029 DOI: 10.1371/Journal.Pone.0132701 |
0.486 |
|
| 2015 |
De Cremer K, Staes I, Delattin N, Cammue BP, Thevissen K, De Brucker K. Combinatorial drug approaches to tackle Candida albicans biofilms. Expert Review of Anti-Infective Therapy. 13: 973-84. PMID 26070384 DOI: 10.1586/14787210.2015.1056162 |
0.333 |
|
| 2015 |
Bardiot D, Thevissen K, De Brucker K, Peeters A, Cos P, Taborda CP, McNaughton M, Maes L, Chaltin P, Cammue BP, Marchand A. 2-(2-oxo-morpholin-3-yl)-acetamide derivatives as broad-spectrum antifungal agents. Journal of Medicinal Chemistry. 58: 1502-12. PMID 25585716 DOI: 10.1021/Jm501814X |
0.342 |
|
| 2015 |
De Cremer K, Lanckacker E, Cools TL, Bax M, De Brucker K, Cos P, Cammue BP, Thevissen K. Artemisinins, new miconazole potentiators resulting in increased activity against Candida albicans biofilms. Antimicrobial Agents and Chemotherapy. 59: 421-6. PMID 25367916 DOI: 10.1128/Aac.04229-14 |
0.363 |
|
| 2014 |
Liebens V, Gerits E, Knapen WJ, Swings T, Beullens S, Steenackers HP, Robijns S, Lippell A, O'Neill AJ, Veber M, Fröhlich M, Krona A, Lövenklev M, Corbau R, Marchand A, ... ... Thevissen K, et al. Identification and characterization of an anti-pseudomonal dichlorocarbazol derivative displaying anti-biofilm activity. Bioorganic & Medicinal Chemistry Letters. 24: 5404-8. PMID 25453797 DOI: 10.1016/J.Bmcl.2014.10.039 |
0.337 |
|
| 2014 |
De Cremer K, Delattin N, De Brucker K, Peeters A, Kucharíková S, Gerits E, Verstraeten N, Michiels J, Van Dijck P, Cammue BP, Thevissen K. Oral administration of the broad-spectrum antibiofilm compound toremifene inhibits Candida albicans and Staphylococcus aureus biofilm formation in vivo. Antimicrobial Agents and Chemotherapy. 58: 7606-10. PMID 25288093 DOI: 10.1128/Aac.03869-14 |
0.342 |
|
| 2014 |
Spincemaille P, Alborzinia H, Dekervel J, Windmolders P, van Pelt J, Cassiman D, Cheneval O, Craik DJ, Schur J, Ott I, Wölfl S, Cammue BP, Thevissen K. The plant decapeptide OSIP108 can alleviate mitochondrial dysfunction induced by cisplatin in human cells. Molecules (Basel, Switzerland). 19: 15088-102. PMID 25244288 DOI: 10.3390/Molecules190915088 |
0.372 |
|
| 2014 |
Vriens K, Cammue BP, Thevissen K. Antifungal plant defensins: mechanisms of action and production. Molecules (Basel, Switzerland). 19: 12280-303. PMID 25153857 DOI: 10.3390/Molecules190812280 |
0.448 |
|
| 2014 |
De Brucker K, Delattin N, Robijns S, Steenackers H, Verstraeten N, Landuyt B, Luyten W, Schoofs L, Dovgan B, Fröhlich M, Michiels J, Vanderleyden J, Cammue BP, Thevissen K. Derivatives of the mouse cathelicidin-related antimicrobial peptide (CRAMP) inhibit fungal and bacterial biofilm formation. Antimicrobial Agents and Chemotherapy. 58: 5395-404. PMID 24982087 DOI: 10.1128/Aac.03045-14 |
0.391 |
|
| 2014 |
Spincemaille P, Matmati N, Hannun YA, Cammue BP, Thevissen K. Sphingolipids and mitochondrial function in budding yeast. Biochimica Et Biophysica Acta. 1840: 3131-7. PMID 24973565 DOI: 10.1016/J.Bbagen.2014.06.015 |
0.313 |
|
| 2014 |
Delattin N, De Brucker K, Craik DJ, Cheneval O, De Coninck B, Cammue BP, Thevissen K. Structure-activity relationship study of the plant-derived decapeptide OSIP108 inhibiting Candida albicans biofilm formation. Antimicrobial Agents and Chemotherapy. 58: 4974-7. PMID 24913176 DOI: 10.1128/Aac.03336-14 |
0.379 |
|
| 2014 |
Troskie AM, Rautenbach M, Delattin N, Vosloo JA, Dathe M, Cammue BP, Thevissen K. Synergistic activity of the tyrocidines, antimicrobial cyclodecapeptides from Bacillus aneurinolyticus, with amphotericin B and caspofungin against Candida albicans biofilms. Antimicrobial Agents and Chemotherapy. 58: 3697-707. PMID 24752256 DOI: 10.1128/Aac.02381-14 |
0.39 |
|
| 2014 |
Spincemaille P, Chandhok G, Newcomb B, Verbeek J, Vriens K, Zibert A, Schmidt H, Hannun YA, van Pelt J, Cassiman D, Cammue BP, Thevissen K. The plant decapeptide OSIP108 prevents copper-induced apoptosis in yeast and human cells. Biochimica Et Biophysica Acta. 1843: 1207-15. PMID 24632503 DOI: 10.1016/J.Bbamcr.2014.03.004 |
0.311 |
|
| 2014 |
Delattin N, De Brucker K, Craik DJ, Cheneval O, Fröhlich M, Veber M, Girandon L, Davis TR, Weeks AE, Kumamoto CA, Cos P, Coenye T, De Coninck B, Cammue BP, Thevissen K. Plant-derived decapeptide OSIP108 interferes with Candida albicans biofilm formation without affecting cell viability. Antimicrobial Agents and Chemotherapy. 58: 2647-56. PMID 24566179 DOI: 10.1128/Aac.01274-13 |
0.411 |
|
| 2014 |
Delattin N, Cammue BP, Thevissen K. Reactive oxygen species-inducing antifungal agents and their activity against fungal biofilms. Future Medicinal Chemistry. 6: 77-90. PMID 24358949 DOI: 10.4155/Fmc.13.189 |
0.392 |
|
| 2014 |
Delattin N, De Brucker K, Vandamme K, Meert E, Marchand A, Chaltin P, Cammue BP, Thevissen K. Repurposing as a means to increase the activity of amphotericin B and caspofungin against Candida albicans biofilms. The Journal of Antimicrobial Chemotherapy. 69: 1035-44. PMID 24284780 DOI: 10.1093/Jac/Dkt449 |
0.348 |
|
| 2013 |
Knez K, Noppe W, Geukens N, Janssen KP, Spasic D, Heyligen J, Vriens K, Thevissen K, Cammue BP, Petrenko V, Ulens C, Deckmyn H, Lammertyn J. Affinity comparison of p3 and p8 peptide displaying bacteriophages using surface plasmon resonance. Analytical Chemistry. 85: 10075-82. PMID 24079816 DOI: 10.1021/Ac402192K |
0.307 |
|
| 2013 |
De Brucker K, Bink A, Meert E, Cammue BP, Thevissen K. Potentiation of antibiofilm activity of amphotericin B by superoxide dismutase inhibition. Oxidative Medicine and Cellular Longevity. 2013: 704654. PMID 24078861 DOI: 10.1155/2013/704654 |
0.349 |
|
| 2013 |
De Coninck B, Carron D, Tavormina P, Willem L, Craik DJ, Vos C, Thevissen K, Mathys J, Cammue BP. Mining the genome of Arabidopsis thaliana as a basis for the identification of novel bioactive peptides involved in oxidative stress tolerance. Journal of Experimental Botany. 64: 5297-307. PMID 24043855 DOI: 10.1093/Jxb/Ert295 |
0.378 |
|
| 2013 |
De Coninck B, Cammue BP, Thevissen K. Modes of antifungal action and in planta functions of plant defensins and defensin-like peptides Fungal Biology Reviews. 26: 109-120. DOI: 10.1016/J.Fbr.2012.10.002 |
0.462 |
|
| 2012 |
Delattin N, Bardiot D, Marchand A, Chaltin P, De Brucker K, Cammue BP, Thevissen K. Identification of fungicidal 2,6-disubstituted quinolines with activity against Candida biofilms. Molecules (Basel, Switzerland). 17: 12243-51. PMID 23079495 DOI: 10.3390/Molecules171012243 |
0.375 |
|
| 2012 |
Bink A, Kucharíková S, Neirinck B, Vleugels J, Van Dijck P, Cammue BP, Thevissen K. The nonsteroidal antiinflammatory drug diclofenac potentiates the in vivo activity of caspofungin against Candida albicans biofilms. The Journal of Infectious Diseases. 206: 1790-7. PMID 22984120 DOI: 10.1093/Infdis/Jis594 |
0.304 |
|
| 2012 |
Liu Q, Luyten W, Pellens K, Wang Y, Wang W, Thevissen K, Liang Q, Cammue BP, Schoofs L, Luo G. Antifungal activity in plants from Chinese traditional and folk medicine. Journal of Ethnopharmacology. 143: 772-8. PMID 22867635 DOI: 10.1016/J.Jep.2012.06.019 |
0.371 |
|
| 2012 |
Fiori A, Kucharíková S, Govaert G, Cammue BP, Thevissen K, Van Dijck P. The heat-induced molecular disaggregase Hsp104 of Candida albicans plays a role in biofilm formation and pathogenicity in a worm infection model. Eukaryotic Cell. 11: 1012-20. PMID 22635920 DOI: 10.1128/Ec.00147-12 |
0.323 |
|
| 2012 |
Bink A, Govaert G, Vandenbosch D, Kuchariková S, Coenye T, Nelis H, Van Dijck P, Cammue BP, Thevissen K. Transcription factor Efg1 contributes to the tolerance of Candida albicans biofilms against antifungal agents in vitro and in vivo. Journal of Medical Microbiology. 61: 813-9. PMID 22422573 DOI: 10.1099/Jmm.0.041020-0 |
0.351 |
|
| 2012 |
Thevissen K, de Mello Tavares P, Xu D, Blankenship J, Vandenbosch D, Idkowiak-Baldys J, Govaert G, Bink A, Rozental S, de Groot PW, Davis TR, Kumamoto CA, Vargas G, Nimrichter L, Coenye T, et al. The plant defensin RsAFP2 induces cell wall stress, septin mislocalization and accumulation of ceramides in Candida albicans. Molecular Microbiology. 84: 166-80. PMID 22384976 DOI: 10.1111/J.1365-2958.2012.08017.X |
0.429 |
|
| 2012 |
Vandenbosch D, Bink A, Govaert G, Cammue BP, Nelis HJ, Thevissen K, Coenye T. Phytosphingosine-1-phosphate is a signaling molecule involved in miconazole resistance in sessile Candida albicans cells. Antimicrobial Agents and Chemotherapy. 56: 2290-4. PMID 22354293 DOI: 10.1128/Aac.05106-11 |
0.307 |
|
| 2011 |
Aerts AM, Bammens L, Govaert G, Carmona-Gutierrez D, Madeo F, Cammue BP, Thevissen K. The Antifungal Plant Defensin HsAFP1 from Heuchera sanguinea Induces Apoptosis in Candida albicans. Frontiers in Microbiology. 2: 47. PMID 21993350 DOI: 10.3389/Fmicb.2011.00047 |
0.475 |
|
| 2011 |
De Brucker K, Cammue BP, Thevissen K. Apoptosis-inducing antifungal peptides and proteins. Biochemical Society Transactions. 39: 1527-32. PMID 21936846 DOI: 10.1042/Bst0391527 |
0.412 |
|
| 2011 |
Bink A, Vandenbosch D, Coenye T, Nelis H, Cammue BP, Thevissen K. Superoxide dismutases are involved in Candida albicans biofilm persistence against miconazole. Antimicrobial Agents and Chemotherapy. 55: 4033-7. PMID 21746956 DOI: 10.1128/Aac.00280-11 |
0.365 |
|
| 2011 |
Wilmes M, Cammue BP, Sahl HG, Thevissen K. Antibiotic activities of host defense peptides: more to it than lipid bilayer perturbation. Natural Product Reports. 28: 1350-8. PMID 21617811 DOI: 10.1039/C1Np00022E |
0.435 |
|
| 2011 |
Thevissen K, Pellens K, De Brucker K, François IE, Chow KK, Meert EM, Meert W, Van Minnebruggen G, Borgers M, Vroome V, Levin J, De Vos D, Maes L, Cos P, Cammue BP. Novel fungicidal benzylsulfanyl-phenylguanidines. Bioorganic & Medicinal Chemistry Letters. 21: 3686-92. PMID 21576022 DOI: 10.1016/J.Bmcl.2011.04.075 |
0.676 |
|
| 2010 |
Bink A, Govaert G, François IE, Pellens K, Meerpoel L, Borgers M, Van Minnebruggen G, Vroome V, Cammue BP, Thevissen K. A fungicidal piperazine-1-carboxamidine induces mitochondrial fission-dependent apoptosis in yeast. Fems Yeast Research. 10: 812-8. PMID 20726898 DOI: 10.1111/J.1567-1364.2010.00663.X |
0.655 |
|
| 2010 |
Thevissen K, Yen WL, Carmona-Gutierrez D, Idkowiak-Baldys J, Aerts AM, François IE, Madeo F, Klionsky DJ, Hannun YA, Cammue BP. Skn1 and Ipt1 negatively regulate autophagy in Saccharomyces cerevisiae. Fems Microbiology Letters. 303: 163-8. PMID 20030721 DOI: 10.1111/J.1574-6968.2009.01869.X |
0.662 |
|
| 2009 |
François IE, Bink A, Vandercappellen J, Ayscough KR, Toulmay A, Schneiter R, van Gyseghem E, Van den Mooter G, Borgers M, Vandenbosch D, Coenye T, Cammue BP, Thevissen K. Membrane rafts are involved in intracellular miconazole accumulation in yeast cells. The Journal of Biological Chemistry. 284: 32680-5. PMID 19783660 DOI: 10.1074/Jbc.M109.014571 |
0.697 |
|
| 2009 |
François IE, Thevissen K, Pellens K, Meert EM, Heeres J, Freyne E, Coesemans E, Viellevoye M, Deroose F, Martinez Gonzalez S, Pastor J, Corens D, Meerpoel L, Borgers M, Ausma J, et al. Design and synthesis of a series of piperazine-1-carboxamidine derivatives with antifungal activity resulting from accumulation of endogenous reactive oxygen species. Chemmedchem. 4: 1714-21. PMID 19705386 DOI: 10.1002/Cmdc.200900249 |
0.671 |
|
| 2009 |
Aerts AM, Carmona-Gutierrez D, Lefevre S, Govaert G, François IE, Madeo F, Santos R, Cammue BP, Thevissen K. The antifungal plant defensin RsAFP2 from radish induces apoptosis in a metacaspase independent way in Candida albicans. Febs Letters. 583: 2513-6. PMID 19596007 DOI: 10.1016/J.Febslet.2009.07.004 |
0.693 |
|
| 2009 |
François IE, Cammue BP, Bresseleers S, Fleuren H, Hoornaert G, Mehta VP, Modha SG, Van der Eycken EV, Thevissen K. Synthesis and fungicidal activity of 3,5-dichloropyrazin-2(1H)-one derivatives. Bioorganic & Medicinal Chemistry Letters. 19: 4064-6. PMID 19556127 DOI: 10.1016/J.Bmcl.2009.06.024 |
0.679 |
|
| 2008 |
Tavares PM, Thevissen K, Cammue BP, François IE, Barreto-Bergter E, Taborda CP, Marques AF, Rodrigues ML, Nimrichter L. In vitro activity of the antifungal plant defensin RsAFP2 against Candida isolates and its in vivo efficacy in prophylactic murine models of candidiasis. Antimicrobial Agents and Chemotherapy. 52: 4522-5. PMID 18824606 DOI: 10.1128/Aac.00448-08 |
0.722 |
|
| 2008 |
Smets B, De Snijder P, Engelen K, Joossens E, Ghillebert R, Thevissen K, Marchal K, Winderickx J. Genome-wide expression analysis reveals TORC1-dependent and -independent functions of Sch9. Fems Yeast Research. 8: 1276-88. PMID 18759743 DOI: 10.1111/J.1567-1364.2008.00432.X |
0.313 |
|
| 2008 |
Thevissen K, Hillaert U, Meert EM, Chow KK, Cammue BP, Van Calenbergh S, François IE. Fungicidal activity of truncated analogues of dihydrosphingosine. Bioorganic & Medicinal Chemistry Letters. 18: 3728-30. PMID 18524581 DOI: 10.1016/J.Bmcl.2008.05.067 |
0.663 |
|
| 2008 |
Aerts AM, Zabrocki P, François IE, Carmona-Gutierrez D, Govaert G, Mao C, Smets B, Madeo F, Winderickx J, Cammue BP, Thevissen K. Ydc1p ceramidase triggers organelle fragmentation, apoptosis and accelerated ageing in yeast. Cellular and Molecular Life Sciences : Cmls. 65: 1933-42. PMID 18500447 DOI: 10.1007/S00018-008-8129-8 |
0.667 |
|
| 2008 |
Aerts AM, François IE, Cammue BP, Thevissen K. The mode of antifungal action of plant, insect and human defensins. Cellular and Molecular Life Sciences : Cmls. 65: 2069-79. PMID 18360739 DOI: 10.1007/S00018-008-8035-0 |
0.701 |
|
| 2007 |
Thevissen K, Kristensen HH, Thomma BP, Cammue BP, François IE. Therapeutic potential of antifungal plant and insect defensins. Drug Discovery Today. 12: 966-71. PMID 17993416 DOI: 10.1016/J.Drudis.2007.07.016 |
0.779 |
|
| 2007 |
Aerts AM, François IE, Meert EM, Li QT, Cammue BP, Thevissen K. The antifungal activity of RsAFP2, a plant defensin from raphanus sativus, involves the induction of reactive oxygen species in Candida albicans. Journal of Molecular Microbiology and Biotechnology. 13: 243-7. PMID 17827975 DOI: 10.1159/000104753 |
0.736 |
|
| 2007 |
Thevissen K, Ayscough KR, Aerts AM, Du W, De Brucker K, Meert EM, Ausma J, Borgers M, Cammue BP, François IE. Miconazole induces changes in actin cytoskeleton prior to reactive oxygen species induction in yeast. The Journal of Biological Chemistry. 282: 21592-7. PMID 17553796 DOI: 10.1074/Jbc.M608505200 |
0.688 |
|
| 2007 |
Aerts AM, Thevissen K, Bresseleers SM, Sels J, Wouters P, Cammue BP, François IE. Arabidopsis thaliana plants expressing human beta-defensin-2 are more resistant to fungal attack: functional homology between plant and human defensins. Plant Cell Reports. 26: 1391-8. PMID 17340092 DOI: 10.1007/S00299-007-0329-4 |
0.721 |
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| 2007 |
Zäuner S, Albrecht S, Ternes P, Thevissen K, Zähringer U, Cammue BP, Heinz E, Warnecke D, Sperling P. Fungal glycosphingolipids in plant/pathogen interactions Chemistry and Physics of Lipids. 149: S73. DOI: 10.1016/J.Chemphyslip.2007.06.167 |
0.399 |
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| 2006 |
Thevissen K, François IE, Winderickx J, Pannecouque C, Cammue BP. Ceramide involvement in apoptosis and apoptotic diseases. Mini Reviews in Medicinal Chemistry. 6: 699-709. PMID 16787381 DOI: 10.2174/138955706777435643 |
0.637 |
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| 2006 |
Aerts AM, François IE, Bammens L, Cammue BP, Smets B, Winderickx J, Accardo S, De Vos DE, Thevissen K. Level of M(IP)2C sphingolipid affects plant defensin sensitivity, oxidative stress resistance and chronological life-span in yeast. Febs Letters. 580: 1903-7. PMID 16527275 DOI: 10.1016/J.Febslet.2006.02.061 |
0.679 |
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| 2006 |
Thevissen K, Francois IE, Aerts AM, Cammue BP. Fungal sphingolipids as targets for the development of selective antifungal therapeutics. Current Drug Targets. 6: 923-8. PMID 16375675 DOI: 10.2174/138945005774912771 |
0.701 |
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| 2006 |
Francois I, Cammue B, Borgers M, Ausma J, Dispersyn G, Thevissen K. Azoles: Mode of Antifungal Action and Resistance Development. Effect of Miconazole on Endogenous Reactive Oxygen Species Production in Candida albicans Anti-Infective Agents in Medicinal Chemistry. 5: 3-13. DOI: 10.2174/187152106774755554 |
0.302 |
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| 2005 |
Francois IE, Aerts AM, Cammue BP, Thevissen K. Currently used antimycotics: spectrum, mode of action and resistance occurrence. Current Drug Targets. 6: 895-907. PMID 16375673 DOI: 10.2174/138945005774912744 |
0.646 |
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| 2005 |
Thevissen K, François IE, Sijtsma L, van Amerongen A, Schaaper WM, Meloen R, Posthuma-Trumpie T, Broekaert WF, Cammue BP. Antifungal activity of synthetic peptides derived from Impatiens balsamina antimicrobial peptides Ib-AMP1 and Ib-AMP4. Peptides. 26: 1113-9. PMID 15949628 DOI: 10.1016/J.Peptides.2005.01.008 |
0.764 |
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| 2005 |
Thevissen K, Idkowiak-Baldys J, Im YJ, Takemoto J, François IEJA, Ferket KKA, Aerts AM, Meert EMK, Winderickx J, Roosen J, Cammue BPA. SKN1, a novel plant defensin-sensitivity gene in Saccharomyces cerevisiae, is implicated in sphingolipid biosynthesis Febs Letters. 579: 1973-1977. PMID 15792805 DOI: 10.1016/J.Febslet.2005.02.043 |
0.684 |
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| 2005 |
Park C, Bennion B, François IE, Ferket KK, Cammue BP, Thevissen K, Levery SB. Neutral glycolipids of the filamentous fungus Neurospora crassa: altered expression in plant defensin-resistant mutants. Journal of Lipid Research. 46: 759-68. PMID 15654124 DOI: 10.1194/Jlr.M400457-Jlr200 |
0.713 |
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| 2004 |
Thevissen K, Warnecke DC, François IE, Leipelt M, Heinz E, Ott C, Zähringer U, Thomma BP, Ferket KK, Cammue BP. Defensins from insects and plants interact with fungal glucosylceramides. The Journal of Biological Chemistry. 279: 3900-5. PMID 14604982 DOI: 10.1074/Jbc.M311165200 |
0.784 |
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| 2003 |
Thevissen K, Ferket KK, François IE, Cammue BP. Interactions of antifungal plant defensins with fungal membrane components. Peptides. 24: 1705-12. PMID 15019201 DOI: 10.1016/J.Peptides.2003.09.014 |
0.728 |
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| 2003 |
Ferket KK, Levery SB, Park C, Cammue BP, Thevissen K. Isolation and characterization of Neurospora crassa mutants resistant to antifungal plant defensins. Fungal Genetics and Biology : Fg & B. 40: 176-85. PMID 14516770 DOI: 10.1016/S1087-1845(03)00085-9 |
0.458 |
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| 2003 |
Thevissen K, François IE, Takemoto JY, Ferket KK, Meert EM, Cammue BP. DmAMP1, an antifungal plant defensin from dahlia (Dahlia merckii), interacts with sphingolipids from Saccharomyces cerevisiae. Fems Microbiology Letters. 226: 169-73. PMID 13129623 DOI: 10.1016/S0378-1097(03)00590-1 |
0.702 |
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| 2003 |
Im YJ, Idkowiak-Baldys J, Thevissen K, Cammue BP, Takemoto JY. IPT1-independent sphingolipid biosynthesis and yeast inhibition by syringomycin E and plant defensin DmAMP1. Fems Microbiology Letters. 223: 199-203. PMID 12829286 DOI: 10.1016/S0378-1097(03)00375-6 |
0.401 |
|
| 2003 |
Thomma BP, Cammue BP, Thevissen K. Mode of action of plant defensins suggests therapeutic potential. Current Drug Targets. Infectious Disorders. 3: 1-8. PMID 12570728 DOI: 10.2174/1568005033342000 |
0.66 |
|
| 2002 |
Thomma BP, Cammue BP, Thevissen K. Plant defensins. Planta. 216: 193-202. PMID 12447532 DOI: 10.1007/s00425-002-0902-6 |
0.602 |
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| 2002 |
Moerman L, Bosteels S, Noppe W, Willems J, Clynen E, Schoofs L, Thevissen K, Tytgat J, Van Eldere J, Van Der Walt J, Verdonck F. Antibacterial and antifungal properties of alpha-helical, cationic peptides in the venom of scorpions from southern Africa. European Journal of Biochemistry. 269: 4799-810. PMID 12354111 DOI: 10.1046/J.1432-1033.2002.03177.X |
0.367 |
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| 2001 |
Schaaper WM, Posthuma GA, Plasman HH, Sijtsma L, Fant F, Borremans FA, Thevissen K, Broekaert WF, Meloen RH, van Amerongen A. Synthetic peptides derived from the beta2-beta3 loop of Raphanus sativus antifungal protein 2 that mimic the active site. The Journal of Peptide Research : Official Journal of the American Peptide Society. 57: 409-18. PMID 11350601 DOI: 10.1034/J.1399-3011.2001.00842.X |
0.621 |
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| 2001 |
Serna A, Maitz M, O'Connell T, Santandrea G, Thevissen K, Tienens K, Hueros G, Faleri C, Cai G, Lottspeich F, Thompson RD. Maize endosperm secretes a novel antifungal protein into adjacent maternal tissue. The Plant Journal : For Cell and Molecular Biology. 25: 687-98. PMID 11319035 DOI: 10.1046/J.1365-313X.2001.01004.X |
0.377 |
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| 2000 |
Thevissen K, Cammue BP, Lemaire K, Winderickx J, Dickson RC, Lester RL, Ferket KK, Van Even F, Parret AH, Broekaert WF. A gene encoding a sphingolipid biosynthesis enzyme determines the sensitivity of Saccharomyces cerevisiae to an antifungal plant defensin from dahlia (Dahlia merckii). Proceedings of the National Academy of Sciences of the United States of America. 97: 9531-6. PMID 10931938 DOI: 10.1073/Pnas.160077797 |
0.666 |
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| 2000 |
Thevissen K, Osborn RW, Acland DP, Broekaert WF. Specific binding sites for an antifungal plant defensin from Dahlia (Dahlia merckii) on fungal cells are required for antifungal activity. Molecular Plant-Microbe Interactions : Mpmi. 13: 54-61. PMID 10656585 DOI: 10.1094/Mpmi.2000.13.1.54 |
0.669 |
|
| 1999 |
Thevissen K, Terras FR, Broekaert WF. Permeabilization of fungal membranes by plant defensins inhibits fungal growth. Applied and Environmental Microbiology. 65: 5451-8. PMID 10584003 DOI: 10.1128/Aem.65.12.5451-5458.1999 |
0.802 |
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| 1997 |
Thevissen K, Osborn RW, Acland DP, Broekaert WF. Specific, high affinity binding sites for an antifungal plant defensin on Neurospora crassa hyphae and microsomal membranes. The Journal of Biological Chemistry. 272: 32176-81. PMID 9405418 DOI: 10.1074/Jbc.272.51.32176 |
0.651 |
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| 1997 |
De Samblanx GW, Goderis IJ, Thevissen K, Raemaekers R, Fant F, Borremans F, Acland DP, Osborn RW, Patel S, Broekaert WF. Mutational analysis of a plant defensin from radish (Raphanus sativus L.) reveals two adjacent sites important for antifungal activity. The Journal of Biological Chemistry. 272: 1171-9. PMID 8995418 DOI: 10.1074/Jbc.272.2.1171 |
0.633 |
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| 1997 |
Broekaert WF, Cammue BPA, De Bolle MFC, Thevissen K, De Samblanx GW, Osborn RW, Nielson K. Antimicrobial Peptides from Plants Critical Reviews in Plant Sciences. 16: 297-323. DOI: 10.1080/07352689709701952 |
0.66 |
|
| 1996 |
Thevissen K, Ghazi A, De Samblanx GW, Brownlee C, Osborn RW, Broekaert WF. Fungal membrane responses induced by plant defensins and thionins. The Journal of Biological Chemistry. 271: 15018-25. PMID 8663029 DOI: 10.1074/Jbc.271.25.15018 |
0.664 |
|
| 1995 |
Osborn RW, De Samblanx GW, Thevissen K, Goderis I, Torrekens S, Van Leuven F, Attenborough S, Rees SB, Broekaert WF. Isolation and characterisation of plant defensins from seeds of Asteraceae, Fabaceae, Hippocastanaceae and Saxifragaceae. Febs Letters. 368: 257-62. PMID 7628617 DOI: 10.1016/0014-5793(95)00666-W |
0.669 |
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| 1995 |
Cammue BP, Thevissen K, Hendriks M, Eggermont K, Goderis IJ, Proost P, Van Damme J, Osborn RW, Guerbette F, Kader JC. A potent antimicrobial protein from onion seeds showing sequence homology to plant lipid transfer proteins. Plant Physiology. 109: 445-55. PMID 7480341 DOI: 10.1104/Pp.109.2.445 |
0.407 |
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| 1994 |
Cammue BP, De Bolle MF, Schoofs HM, Terras FR, Thevissen K, Osborn RW, Rees SB, Broekaert WF. Gene-encoded antimicrobial peptides from plants. Ciba Foundation Symposium. 186: 91-101; discussion 1. PMID 7768160 |
0.797 |
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| 1993 |
Terras F, Schoofs H, Thevissen K, Osborn RW, Vanderleyden J, Cammue B, Broekaert WF. Synergistic Enhancement of the Antifungal Activity of Wheat and Barley Thionins by Radish and Oilseed Rape 2S Albumins and by Barley Trypsin Inhibitors. Plant Physiology. 103: 1311-1319. PMID 12232024 DOI: 10.1104/Pp.103.4.1311 |
0.769 |
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