Tom (N.) Taghon - Publications

Affiliations: 
2005 California Institute of Technology, Pasadena, CA 

123 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Assatova B, Willim R, Trevisani C, Haskett G, Kariya KM, Chopra K, Park SR, Tolstorukov MY, McCabe SM, Duffy J, Louissaint A, Huuhtanen J, Bhattacharya D, Mustjoki S, Koh MJ, ... ... Taghon T, et al. KLRG1 Cell Depletion As A Novel Therapeutic Strategy In Patients With Mature T-cell lymphoma Subtypes. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 38252421 DOI: 10.1158/1078-0432.CCR-23-3504  0.566
2023 Yayon N, Kedlian VR, Boehme L, Suo C, Wachter B, Beuschel RT, Amsalem O, Polanski K, Koplev S, Tuck E, Dann E, Van Hulle J, Perera S, Putteman T, Predeus AV, ... ... Taghon T, et al. A spatial human thymus cell atlas mapped to a continuous tissue axis. Biorxiv : the Preprint Server For Biology. PMID 37986877 DOI: 10.1101/2023.10.25.562925  0.505
2023 Liang KL, Laurenti E, Taghon T. Circulating IRF8-expressing CD123CD127 lymphoid progenitors: key players in human hematopoiesis. Trends in Immunology. 44: 678-692. PMID 37591714 DOI: 10.1016/j.it.2023.07.004  0.516
2023 Pille M, Avila J, Sanchez GS, Goetgeluk G, De Munter S, Jansen H, Billiet L, Weening K, Xue H, Bonte S, Ingels J, De Cock L, Pascal E, Deseins L, Kerre T, ... Taghon T, et al. The Wiskott-Aldrich syndrome protein is required for positive selection during T-cell lineage differentiation. Frontiers in Immunology. 14: 1188099. PMID 37350958 DOI: 10.3389/fimmu.2023.1188099  0.677
2023 Billiet L, De Cock L, Sanchez Sanchez G, Mayer RL, Goetgeluk G, De Munter S, Pille M, Ingels J, Jansen H, Weening K, Pascal E, Raes K, Bonte S, Kerre T, Vandamme N, ... ... Taghon T, et al. Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage. The Journal of Experimental Medicine. 220. PMID 36939517 DOI: 10.1084/jem.20220942  0.546
2023 Guo H, Xu J, Xing P, Li Q, Wang D, Tang C, Palhais B, Roels J, Liu J, Pan S, Huang J, Liu Z, Zhu P, Taghon T, Qing G, et al. RNA helicase DHX15 exemplifies a unique dependency in acute leukemia. Haematologica. PMID 36861414 DOI: 10.3324/haematol.2022.282066  0.614
2023 Provez L, Putteman T, Landfors M, Roels J, Reunes L, T'Sas S, Van Loocke W, Lintermans B, De Coninck S, Thenoz M, Sleeckx W, Maćkowska-Maślak N, Taghon T, Mansour MR, Farah N, et al. Pre-Clinical Evaluation of the Hypomethylating Agent Decitabine for the Treatment of T-Cell Lymphoblastic Lymphoma. Cancers. 15. PMID 36765607 DOI: 10.3390/cancers15030647  0.568
2023 Liang KL, Roels J, Lavaert M, Putteman T, Boehme L, Tilleman L, Velghe I, Pegoretti V, Van de Walle I, Sontag S, Vandewalle J, Vandekerckhove B, Leclercq G, Van Vlierberghe P, Libert C, ... ... Taghon T, et al. Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF. Nature Immunology. PMID 36703005 DOI: 10.1038/s41590-022-01417-6  0.674
2022 Persyn E, Wahlen S, Kiekens L, Van Loocke W, Siwe H, Van Ammel E, De Vos Z, Van Nieuwerburgh F, Matthys P, Taghon T, Vandekerckhove B, Van Vlierberghe P, Leclercq G. IRF2 is required for development and functional maturation of human NK cells. Frontiers in Immunology. 13: 1038821. PMID 36544762 DOI: 10.3389/fimmu.2022.1038821  0.387
2022 Boehme L, Roels J, Taghon T. Development of γδ T cells in the thymus - A human perspective. Seminars in Immunology. 101662. PMID 36374779 DOI: 10.1016/j.smim.2022.101662  0.655
2022 Lambrechts N, Liang KL, Velghe I, Strubbe S, Dolens AC, Taghon T. In Vitro Model Systems to Study Human T Cell Development. Methods in Molecular Biology (Clifton, N.J.). 2580: 335-354. PMID 36374468 DOI: 10.1007/978-1-0716-2740-2_21  0.657
2022 Van de Walle I, Lambrechts N, Derveeuw A, Lavaert M, Roels J, Taghon T. Identification and Purification of Human T Cell Precursors. Methods in Molecular Biology (Clifton, N.J.). 2580: 315-333. PMID 36374467 DOI: 10.1007/978-1-0716-2740-2_20  0.468
2022 Kiekens L, Wahlen S, Persyn E, De Vos Z, Taghon T, Vandekerckhove B, Leclercq G. T-BET drives the conversion of human type 3 innate lymphoid cells into functional NK cells. Frontiers in Immunology. 13: 975778. PMID 36330517 DOI: 10.3389/fimmu.2022.975778  0.64
2022 Persyn E, Wahlen S, Kiekens L, Taveirne S, Van Loocke W, Van Ammel E, Van Nieuwerburgh F, Taghon T, Vandekerckhove B, Van Vlierberghe P, Leclercq G. TXNIP Promotes Human NK Cell Development but Is Dispensable for NK Cell Functionality. International Journal of Molecular Sciences. 23. PMID 36232644 DOI: 10.3390/ijms231911345  0.35
2022 Roels J, Van Hulle J, Lavaert M, Kuchmiy A, Strubbe S, Putteman T, Vandekerckhove B, Leclercq G, Van Nieuwerburgh F, Boehme L, Taghon T. Transcriptional dynamics and epigenetic regulation of E and ID protein encoding genes during human T cell development. Frontiers in Immunology. 13: 960918. PMID 35967340 DOI: 10.3389/fimmu.2022.960918  0.652
2022 Wahlen S, Matthijssens F, Van Loocke W, Taveirne S, Kiekens L, Persyn E, Van Ammel E, De Vos Z, De Munter S, Matthys P, Van Nieuwerburgh F, Taghon T, Vandekerckhove B, Van Vlierberghe P, Leclercq G. The transcription factor RUNX2 drives the generation of human NK cells and promotes tissue residency. Elife. 11. PMID 35793229 DOI: 10.7554/eLife.80320  0.343
2022 Drobna-Śledzińska M, Maćkowska-Maślak N, Jaksik R, Kosmalska M, Szarzyńska B, Lejman M, Sędek Ł, Szczepański T, Taghon T, Van Vlierberghe P, Witt M, Dawidowska M. Multiomics to investigate the mechanisms contributing to repression of PTPRC and SOCS2 in pediatric T-ALL: Focus on miR-363-3p and promoter methylation. Genes, Chromosomes & Cancer. PMID 35778917 DOI: 10.1002/gcc.23085  0.529
2021 Strubbe S, Taghon T. Modeling of human T cell development in vitro as a read-out for hematopoietic stem cell multipotency. Biochemical Society Transactions. 49: 2113-2122. PMID 34643218 DOI: 10.1042/BST20210144  0.571
2021 Kiekens L, Van Loocke W, Taveirne S, Wahlen S, Persyn E, Van Ammel E, De Vos Z, Matthys P, Van Nieuwerburgh F, Taghon T, Van Vlierberghe P, Vandekerckhove B, Leclercq G. T-BET and EOMES Accelerate and Enhance Functional Differentiation of Human Natural Killer Cells. Frontiers in Immunology. 12: 732511. PMID 34630413 DOI: 10.3389/fimmu.2021.732511  0.643
2021 Bonte S, de Munter S, Billiet L, Goetgeluk G, Ingels J, Jansen H, Pille M, de Cock L, Weening K, Taghon T, Leclercq G, Vandekerckhove B, Kerre T. OP9-DL1 co-culture and subsequent maturation in the presence of IL-21 generates tumor antigen-specific T cells with a favorable less-differentiated phenotype and enhanced functionality. Oncoimmunology. 10: 1954800. PMID 34367734 DOI: 10.1080/2162402X.2021.1954800  0.637
2021 Ferrua F, Bortolomai I, Fontana E, Di Silvestre D, Rigoni R, Marcovecchio GE, Draghici E, Brambilla F, Castiello MC, Delfanti G, Moshous D, Picard C, Taghon T, Bordon V, Schulz AS, et al. Thymic Epithelial Cell Alterations and Defective Thymopoiesis Lead to Central and Peripheral Tolerance Perturbation in MHCII Deficiency. Frontiers in Immunology. 12: 669943. PMID 34211466 DOI: 10.3389/fimmu.2021.669943  0.391
2021 Moirangthem RD, Ma K, Lizot S, Cordesse A, Olivré J, de Chappedelaine C, Joshi A, Cieslak A, Tchen J, Cagnard N, Asnafi V, Rausell A, Simons L, Zuber J, Taghon T, et al. A DL-4- and TNFα-based culture system to generate high numbers of nonmodified or genetically modified immunotherapeutic human T-lymphoid progenitors. Cellular & Molecular Immunology. PMID 34117371 DOI: 10.1038/s41423-021-00706-8  0.634
2021 Tottone L, Lancho O, Loh JW, Singh A, Kimura S, Roels J, Kuchmiy A, Strubbe S, Lawlor MA, da Silva-Diz V, Luo S, Gachet S, García-Prieto CA, Hagelaar R, Esteller M, ... ... Taghon T, et al. A Tumor Suppressor Enhancer of in T-cell development and leukemia. Blood Cancer Discovery. 2: 92-109. PMID 33458694 DOI: 10.1158/2643-3230.BCD-20-0201  0.635
2021 Buratin A, Paganin M, Gaffo E, Dal Molin A, Roels J, Germano G, Siddi MT, Serafin V, De Decker M, Gachet S, Durinck K, Speleman F, Taghon T, Te Kronnie G, Van Vlierberghe P, et al. Large-scale circular RNA deregulation in T-ALL: unlocking unique ectopic expression of molecular subtypes. Blood Advances. 4: 5902-5914. PMID 33259601 DOI: 10.1182/bloodadvances.2020002337  0.613
2020 Loontiens S, Dolens AC, Strubbe S, Van de Walle I, Moore FE, Depestel L, Vanhauwaert S, Matthijssens F, Langenau DM, Speleman F, Van Vlierberghe P, Durinck K, Taghon T. PHF6 Expression Levels Impact Human Hematopoietic Stem Cell Differentiation. Frontiers in Cell and Developmental Biology. 8: 599472. PMID 33251223 DOI: 10.3389/fcell.2020.599472  0.574
2020 Roels J, Thénoz M, Szarzyńska B, Landfors M, De Coninck S, Demoen L, Provez L, Kuchmiy A, Strubbe S, Reunes L, Pieters T, Matthijssens F, Van Loocke W, Erarslan-Uysal B, Richter-Pechańska P, ... ... Taghon T, et al. Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia. Blood Cancer Discovery. 1: 274-289. PMID 33179015 DOI: 10.1158/2643-3230.BCD-20-0059  0.589
2020 Lavaert M, Valcke B, Vandekerckhove B, Leclercq G, Liang KL, Taghon T. Conventional and Computational Flow Cytometry Analyses Reveal Sustained Human Intrathymic T Cell Development From Birth Until Puberty. Frontiers in Immunology. 11: 1659. PMID 32849574 DOI: 10.3389/fimmu.2020.01659  0.478
2020 Roels J, Kuchmiy A, De Decker M, Strubbe S, Lavaert M, Liang KL, Leclercq G, Vandekerckhove B, Van Nieuwerburgh F, Van Vlierberghe P, Taghon T. Distinct and temporary-restricted epigenetic mechanisms regulate human αβ and γδ T cell development. Nature Immunology. PMID 32719521 DOI: 10.1038/s41590-020-0747-9  0.712
2020 Garcia EG, Veloso A, Oliveira ML, Allen JR, Loontiens S, Brunson D, Do D, Yan C, Morris R, Iyer S, Garcia SP, Iftimia N, Van Loocke W, Matthijssens F, McCarthy K, ... ... Taghon T, et al. PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis. Leukemia. PMID 32606318 DOI: 10.1038/s41375-020-0937-3  0.664
2020 Zhou Y, Han C, Wang E, Lorch AH, Serafin V, Cho BK, Guttierrez Diaz BT, Calvo J, Fang C, Khodadadi-Jamayran A, Tabaglio T, Marier C, Kuchmiy A, Sun L, Yacu G, ... ... Taghon T, et al. Posttranslational regulation of the exon skipping machinery controls aberrant splicing in leukemia. Cancer Discovery. PMID 32444465 DOI: 10.1158/2159-8290.Cd-19-1436  0.545
2020 Taveirne S, Wahlen S, Van Loocke W, Kiekens L, Persyn E, Van Ammel E, De Mulder K, Roels J, Tilleman L, Aumercier M, Matthys P, Van Nieuwerburgh F, Kerre TCC, Taghon T, Van Vlierberghe P, et al. The transcription factor ETS1 is an important regulator of human NK cell development and terminal differentiation. Blood. PMID 32350509 DOI: 10.1182/blood.2020005204  0.423
2020 De Smedt R, Morscio J, Reunes L, Roels J, Bardelli V, Lintermans B, Van Loocke W, Almeida ARM, Cheung LC, Kotecha RS, Mansour MR, Uyttebroeck A, Vandenberghe P, La Starza R, Mecucci C, ... ... Taghon T, et al. Targeting cytokine and therapy induced PIM1 activation in T-cell acute lymphoblastic leukemia and lymphoma. Blood. PMID 32315407 DOI: 10.1182/blood.2019003880  0.609
2020 Lavaert M, Liang KL, Vandamme N, Park JE, Roels J, Kowalczyk MS, Li B, Ashenberg O, Tabaka M, Dionne D, Tickle TL, Slyper M, Rozenblatt-Rosen O, Vandekerckhove B, Leclercq G, ... ... Taghon T, et al. Integrated scRNA-Seq Identifies Human Postnatal Thymus Seeding Progenitors and Regulatory Dynamics of Differentiating Immature Thymocytes. Immunity. PMID 32304633 DOI: 10.1016/J.Immuni.2020.03.019  0.522
2020 Ingels J, De Smet S, Heyns K, Lootens N, Segaert J, Taghon T, Leclercq G, Vermaelen K, Willems E, Baudoux E, Kerre T, Baron F, Vandekerckhove B. Treatment of a patient with severe cytomegalovirus (CMV) infection after haploidentical stem cell transplantation with donor-derived CMV-specific T cells. Acta Clinica Belgica. 1-5. PMID 32285755 DOI: 10.1080/17843286.2020.1752446  0.524
2020 Dolens AC, Durinck K, Lavaert M, Van der Meulen J, Velghe I, De Medts J, Weening K, Roels J, De Mulder K, Volders PJ, De Preter K, Kerre T, Vandekerckhove B, Leclercq G, Vandesompele J, ... ... Taghon T, et al. Distinct Notch1 and BCL11B requirements mediate human γδ/αβ T cell development. Embo Reports. e49006. PMID 32255245 DOI: 10.15252/Embr.201949006  0.547
2020 Bonte S, De Munter S, Goetgeluk G, Ingels J, Pille M, Billiet L, Taghon T, Leclercq G, Vandekerckhove B, Kerre T. T-cells with a single tumor antigen-specific T-cell receptor can be generated from clinically relevant stem cell sources. Oncoimmunology. 9: 1727078. PMID 32117593 DOI: 10.1080/2162402X.2020.1727078  0.637
2020 Park JE, Botting RA, Domínguez Conde C, Popescu DM, Lavaert M, Kunz DJ, Goh I, Stephenson E, Ragazzini R, Tuck E, Wilbrey-Clark A, Roberts K, Kedlian VR, Ferdinand JR, He X, ... ... Taghon T, et al. A cell atlas of human thymic development defines T cell repertoire formation. Science (New York, N.Y.). 367. PMID 32079746 DOI: 10.1126/Science.Aay3224  0.641
2020 De Munter S, Van Parys A, Bral L, Ingels J, Goetgeluk G, Bonte S, Pille M, Billiet L, Weening K, Verhee A, Van der Heyden J, Taghon T, Leclercq G, Kerre T, Tavernier J, et al. Rapid and Effective Generation of Nanobody Based CARs using PCR and Gibson Assembly. International Journal of Molecular Sciences. 21. PMID 32019116 DOI: 10.3390/ijms21030883  0.525
2020 De Decker M, Lavaert M, Roels J, Tilleman L, Vandekerckhove B, Leclercq G, Van Nieuwerburgh F, Van Vlierberghe P, Taghon T. HES1 and HES4 have non-redundant roles downstream of Notch during early human T cell development. Haematologica. PMID 31919081 DOI: 10.3324/haematol.2019.226126  0.727
2020 Roels J, Thénoz M, Szarzyńska B, Landfors M, De Coninck S, Demoen L, Provez L, Kuchmiy A, Strubbe S, Reunes L, Pieters T, Matthijssens F, Van Loocke W, Lammens T, De Moerloose B, ... ... Taghon T, et al. Aging of Preleukemic Thymocytes Drives CpG Island Hypermethylation in T-Cell Acute Lymphoblastic Leukemia Blood. 136: 28-29. DOI: 10.1182/blood-2020-138501  0.534
2019 Bonnardel J, T'Jonck W, Gaublomme D, Browaeys R, Scott CL, Martens L, Vanneste B, De Prijck S, Nedospasov SA, Kremer A, Van Hamme E, Borghgraef P, Toussaint W, De Bleser P, Mannaerts I, ... ... Taghon T, et al. Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche. Immunity. PMID 31561945 DOI: 10.1016/J.Immuni.2019.08.017  0.345
2019 De Coninck S, Berx G, Taghon T, Van Vlierberghe P, Goossens S. ZEB2 in T-cells and T-ALL. Advances in Biological Regulation. 100639. PMID 31383581 DOI: 10.1016/j.jbior.2019.100639  0.667
2019 Habets RA, de Bock CE, Serneels L, Lodewijckx I, Verbeke D, Nittner D, Narlawar R, Demeyer S, Dooley J, Liston A, Taghon T, Cools J, de Strooper B. Safe targeting of T cell acute lymphoblastic leukemia by pathology-specific NOTCH inhibition. Science Translational Medicine. 11. PMID 31142678 DOI: 10.1126/scitranslmed.aau6246  0.59
2019 Goossens S, Wang J, Tremblay C, De Medts J, T'Sas S, Nguyen T, Saw J, Haigh K, Curtis DJ, Van Vlierberghe P, Berx G, Taghon T, Haigh JJ. ZEB2 and LMO2 drive immature T-cell lymphoblastic leukemia via distinct oncogenic mechanisms. Haematologica. PMID 30679322 DOI: 10.3324/haematol.2018.207837  0.694
2019 Loontiens S, Durinck K, Vanhauwaert S, Depestel L, Oliveira M, Dewyn G, de Bock C, Barata J, Langenau D, Cools J, Taghon T, Van Vlierberghe P, Speleman F. PS920 PHF6 LOSS DRIVES IL7R ONCOGENE ADDICTION IN TLX1 DRIVEN T-ALL Hemasphere. 3: 414-415. DOI: 10.1097/01.HS9.0000561956.76629.C7  0.48
2019 de Bock C, Habets R, Serneels L, Lodewijckx I, Verbeke D, Nittner D, Narlawar R, Demeyer S, Dooley J, Liston A, Taghon T, de Strooper B, Cools J. PS917 SAFE TARGETING OF T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA BY SUBUNIT SELECTIVE GAMMA-SECRETASE INHIBITION Hemasphere. 3: 413-414. DOI: 10.1097/01.HS9.0000561948.38512.48  0.45
2019 Thenoz M, Roels J, Reunes L, Pieters T, Peirs S, Milani G, Van Loocke W, Lammens T, Deforce D, Van Nieuwerburgh F, Mansour M, Taghon T, Gossens S, Van Vlierberghe P. S860 TARGETING ABERRANT DNA METHYLATION AS A NOVEL AND UNIFORM THERAPEUTIC STRATEGY FOR THE TREATMENT OF T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA AND LYMPHOMA Hemasphere. 3: 384-385. DOI: 10.1097/01.HS9.0000561720.13984.B8  0.349
2018 de Bock CE, Down M, Baidya K, Sweron B, Boyd AW, Fiers M, Burns GF, Molloy TJ, Lock RB, Soulier J, Taghon T, Van Vlierberghe P, Cools J, Holst J, Thorne RF. T-cell acute lymphoblastic leukemia express a unique truncated FAT1 isoform that cooperates with NOTCH1 in leukemia development. Haematologica. PMID 30514801 DOI: 10.3324/haematol.2018.198424  0.55
2018 Su H, Hu J, Huang L, Yang Y, Thenoz M, Kuchmiy A, Hu Y, Li P, Feng H, Zhou Y, Taghon T, Van Vlierberghe P, Qing G, Chen Z, Liu H. SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival. Nature Communications. 9: 4281. PMID 30323192 DOI: 10.1038/s41467-018-06523-4  0.64
2018 Gachet S, El-Chaar T, Avran D, Genescà E, Catez F, Quentin S, Delord M, Thérizols G, Briot D, Meunier G, Hernandez L, Pla M, Smits WK, Buijs-Gladdines JGCAM, Van Loocke W, ... ... Taghon T, et al. Deletion 6q drives T-cell leukemia progression by ribosome modulation. Cancer Discovery. PMID 30266814 DOI: 10.1158/2159-8290.CD-17-0831  0.437
2017 Simons L, Ma K, de Chappedelaine C, Moiranghtem RD, Elkaim E, Olivré J, Susini S, Appourchaux K, Reimann C, Sadek H, Pellé O, Cagnard N, Magrin E, Lagresle-Peyrou C, Taghon T, et al. Generation of adult human T cell progenitors for immunotherapeutic applications. The Journal of Allergy and Clinical Immunology. PMID 29208547 DOI: 10.1016/J.Jaci.2017.10.034  0.512
2017 Wallaert A, Van Loocke W, Hernandez L, Taghon T, Speleman F, Van Vlierberghe P. Comprehensive miRNA expression profiling in human T-cell acute lymphoblastic leukemia by small RNA-sequencing. Scientific Reports. 7: 7901. PMID 28801656 DOI: 10.1038/s41598-017-08148-x  0.458
2017 Verstichel G, Vermijlen D, Martens L, Goetgeluk G, Brouwer M, Thiault N, Van Caeneghem Y, De Munter S, Weening K, Bonte S, Leclercq G, Taghon T, Kerre T, Saeys Y, Van Dorpe J, et al. The checkpoint for agonist selection precedes conventional selection in human thymus. Science Immunology. 2. PMID 28783686 DOI: 10.1126/sciimmunol.aah4232  0.455
2017 Van Acker A, Gronke K, Biswas A, Martens L, Saeys Y, Filtjens J, Taveirne S, Van Ammel E, Kerre T, Matthys P, Taghon T, Vandekerckhove B, Plum J, Dunay IR, Diefenbach A, et al. A Murine Intestinal Intraepithelial NKp46-Negative Innate Lymphoid Cell Population Characterized by Group 1 Properties. Cell Reports. 19: 1431-1443. PMID 28514662 DOI: 10.1016/j.celrep.2017.04.068  0.515
2017 Dolens AC, Taghon T. Human T cell development notched up a level. Nature Methods. 14: 477-478. PMID 28448067 DOI: 10.1038/nmeth.4277  0.584
2017 Van Caeneghem Y, De Munter S, Tieppo P, Goetgeluk G, Weening K, Verstichel G, Bonte S, Taghon T, Leclercq G, Kerre T, Debets R, Vermijlen D, Abken H, Vandekerckhove B. Antigen receptor-redirected T cells derived from hematopoietic precursor cells lack expression of the endogenous TCR/CD3 receptor and exhibit specific antitumor capacities. Oncoimmunology. 6: e1283460. PMID 28405508 DOI: 10.1080/2162402X.2017.1283460  0.651
2017 Wallaert A, Durinck K, Taghon T, Van Vlierberghe P, Speleman F. T-ALL and thymocytes: a message of noncoding RNAs. Journal of Hematology & Oncology. 10: 66. PMID 28270163 DOI: 10.1186/s13045-017-0432-0  0.544
2017 Liang KL, Van de Walle I, Tilleman L, Van Nieuwerburgh F, Taghon T. GATA-3 Suppresses IRF8 to promote human T-cell lineage commitment Experimental Hematology. 53: S83. DOI: 10.1016/J.EXPHEM.2017.06.185  0.625
2016 Filtjens J, Coltel N, Cencig S, Taveirne S, Van Ammel E, Van Acker A, Kerre T, Matthys P, Taghon T, Vandekerckhove B, Carlier Y, Truyens C, Leclercq G. The Ly49E Receptor Inhibits the Immune Control of Acute Trypanosoma cruzi Infection. Frontiers in Immunology. 7: 472. PMID 27891126 DOI: 10.3389/fimmu.2016.00472  0.322
2016 Unnikrishnan A, Guan YF, Huang Y, Beck D, Thoms JA, Peirs S, Knezevic K, Ma S, de Walle IV, de Jong I, Ali Z, Zhong L, Raftery MJ, Taghon T, Larsson J, et al. A quantitative proteomics approach identifies ETV6 and IKZF1 as new regulators of an ERG-driven transcriptional network. Nucleic Acids Research. PMID 27604872 DOI: 10.1093/Nar/Gkw804  0.556
2016 Drennan MB, Govindarajan S, Verheugen E, Coquet JM, Staal J, McGuire C, Taghon T, Leclercq G, Beyaert R, van Loo G, Lambrecht BN, Elewaut D. NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNFAIP3/A20. The Journal of Experimental Medicine. PMID 27551157 DOI: 10.1084/Jem.20151065  0.602
2016 Filtjens J, Keirsse J, Van Ammel E, Taveirne S, Van Acker A, Kerre T, Taghon T, Vandekerckhove B, Plum J, Van Ginderachter JA, Leclercq G. Expression of the inhibitory Ly49E receptor is not critically involved in the immune response against cutaneous, pulmonary or liver tumours. Scientific Reports. 6: 30564. PMID 27469529 DOI: 10.1038/srep30564  0.396
2016 Wallaert A, Durinck K, Van Loocke W, Van de Walle I, Matthijssens F, Volders PJ, Avila Cobos F, Rombaut D, Rondou P, Mestdagh P, Vandesompele J, Poppe B, Taghon T, Soulier J, Van Vlierberghe P, et al. Long noncoding RNA signatures define oncogenic subtypes in T-cell acute lymphoblastic leukemia. Leukemia. 30: 1927-30. PMID 27168467 DOI: 10.1038/leu.2016.82  0.41
2016 Van de Walle I, Dolens AC, Durinck K, De Mulder K, Van Loocke W, Damle S, Waegemans E, De Medts J, Velghe I, De Smedt M, Vandekerckhove B, Kerre T, Plum J, Leclercq G, Rothenberg EV, ... ... Taghon T, et al. GATA3 induces human T-cell commitment by restraining Notch activity and repressing NK-cell fate. Nature Communications. 7: 11171. PMID 27048872 DOI: 10.1038/Ncomms11171  0.84
2016 Bonte S, Snauwaert S, Vanhee S, Dolens AC, Taghon T, Vandekerckhove B, Kerre T. Humanized mice to study human T cell development Methods in Molecular Biology. 1323: 253-272. PMID 26294414 DOI: 10.1007/978-1-4939-2809-5_21  0.47
2016 Dolens AC, Van de Walle I, Taghon T. Approaches to Study Human T Cell Development. Methods in Molecular Biology (Clifton, N.J.). 1323: 239-51. PMID 26294413 DOI: 10.1007/978-1-4939-2809-5_20  0.64
2016 Van de Walle I, Davids K, Taghon T. Characterization and Isolation of Human T Cell Progenitors. Methods in Molecular Biology (Clifton, N.J.). 1323: 221-37. PMID 26294412 DOI: 10.1007/978-1-4939-2809-5_19  0.585
2015 Durinck K, Loocke WV, der Meulen JV, de Walle IV, Ongenaert M, Rondou P, Wallaert A, de Bock CE, Roy NV, Poppe B, Cools J, Soulier J, Taghon T, Speleman F, Vlierberghe PV. Characterization of the genome-wide TLX1 binding profile in T-cell acute lymphoblastic leukemia. Leukemia. PMID 26108691 DOI: 10.1038/leu.2015.162  0.626
2015 Goossens S, Radaelli E, Blanchet O, Durinck K, Van der Meulen J, Peirs S, Taghon T, Tremblay CS, Costa M, Farhang Ghahremani M, De Medts J, Bartunkova S, Haigh K, Schwab C, Farla N, et al. ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling. Nature Communications. 6: 5794. PMID 25565005 DOI: 10.1038/Ncomms6794  0.637
2015 Peirs S, Van der Meulen J, Van de Walle I, Taghon T, Speleman F, Poppe B, Van Vlierberghe P. Epigenetics in T-cell acute lymphoblastic leukemia. Immunological Reviews. 263: 50-67. PMID 25510271 DOI: 10.1111/imr.12237  0.65
2015 Vanhee S, De Mulder K, Van Caeneghem Y, Verstichel G, Van Roy N, Menten B, Velghe I, Philippé J, De Bleser D, Lambrecht BN, Taghon T, Leclercq G, Kerre T, Vandekerckhove B. In vitro human embryonic stem cell hematopoiesis mimics MYB-independent yolk sac hematopoiesis. Haematologica. 100: 157-66. PMID 25381126 DOI: 10.3324/haematol.2014.112144  0.363
2015 Van der Meulen J, Sanghvi V, Mavrakis K, Durinck K, Fang F, Matthijssens F, Rondou P, Rosen M, Pieters T, Vandenberghe P, Delabesse E, Lammens T, De Moerloose B, Menten B, Van Roy N, ... ... Taghon T, et al. The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia. Blood. 125: 13-21. PMID 25320243 DOI: 10.1182/blood-2014-05-577270  0.576
2015 Mets E, Van der Meulen J, Van Peer G, Boice M, Mestdagh P, Van de Walle I, Lammens T, Goossens S, De Moerloose B, Benoit Y, Van Roy N, Clappier E, Poppe B, Vandesompele J, Wendel HG, ... Taghon T, et al. MicroRNA-193b-3p acts as a tumor suppressor by targeting the MYB oncogene in T-cell acute lymphoblastic leukemia. Leukemia. 29: 798-806. PMID 25231743 DOI: 10.1038/leu.2014.276  0.496
2015 van Caeneghem Y, Goetgeluk G, Weening K, Verstichel G, Bonte S, Taghon T, Leclercq G, Offner F, Abken H, Kerre T, Vandekerkhove B. Chimeric Antigen Receptor Transgenic, T Cell Receptor/CD3 Negative Monospecific T Cells Generated from Cord Blood CD34 Positive Cells Blood. 126: 3087-3087. DOI: 10.1182/BLOOD.V126.23.3087.3087  0.586
2014 Sanghvi VR, Mavrakis KJ, Van der Meulen J, Boice M, Wolfe AL, Carty M, Mohan P, Rondou P, Socci ND, Benoit Y, Taghon T, Van Vlierberghe P, Leslie CS, Speleman F, Wendel HG. Characterization of a set of tumor suppressor microRNAs in T cell acute lymphoblastic leukemia. Science Signaling. 7: ra111. PMID 25406379 DOI: 10.1126/scisignal.2005500  0.312
2014 Waegemans E, Van de Walle I, De Medts J, De Smedt M, Kerre T, Vandekerckhove B, Leclercq G, Wang T, Plum J, Taghon T. Notch3 activation is sufficient but not required for inducing human T-lineage specification. Journal of Immunology (Baltimore, Md. : 1950). 193: 5997-6004. PMID 25381438 DOI: 10.4049/Jimmunol.1400764  0.614
2014 Durinck K, Wallaert A, Van de Walle I, Van Loocke W, Volders PJ, Vanhauwaert S, Geerdens E, Benoit Y, Van Roy N, Poppe B, Soulier J, Cools J, Mestdagh P, Vandesompele J, Rondou P, ... ... Taghon T, et al. The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia. Haematologica. 99: 1808-16. PMID 25344525 DOI: 10.1182/Blood.V124.21.900.900  0.577
2014 Van Acker A, Filtjens J, Van Welden S, Taveirne S, Van Ammel E, Vanhees M, Devisscher L, Kerre T, Taghon T, Vandekerckhove B, Plum J, Leclercq G. Ly49E expression on CD8αα-expressing intestinal intraepithelial lymphocytes plays no detectable role in the development and progression of experimentally induced inflammatory bowel diseases. Plos One. 9: e110015. PMID 25310588 DOI: 10.1371/journal.pone.0110015  0.338
2014 Peirs S, Matthijssens F, Goossens S, Van de Walle I, Ruggero K, de Bock CE, Degryse S, Canté-Barrett K, Briot D, Clappier E, Lammens T, De Moerloose B, Benoit Y, Poppe B, Meijerink JP, ... ... Taghon T, et al. ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia. Blood. 124: 3738-47. PMID 25301704 DOI: 10.1182/blood-2014-05-574566  0.637
2014 Finalet Ferreiro J, Rouhigharabaei L, Urbankova H, van der Krogt JA, Michaux L, Shetty S, Krenacs L, Tousseyn T, De Paepe P, Uyttebroeck A, Verhoef G, Taghon T, Vandenberghe P, Cools J, Wlodarska I. Integrative genomic and transcriptomic analysis identified candidate genes implicated in the pathogenesis of hepatosplenic T-cell lymphoma. Plos One. 9: e102977. PMID 25057852 DOI: 10.1371/journal.pone.0102977  0.306
2014 Mets E, Van Peer G, Van der Meulen J, Boice M, Taghon T, Goossens S, Mestdagh P, Benoit Y, De Moerloose B, Van Roy N, Poppe B, Vandesompele J, Wendel HG, Van Vlierberghe P, Speleman F, et al. MicroRNA-128-3p is a novel oncomiR targeting PHF6 in T-cell acute lymphoblastic leukemia. Haematologica. 99: 1326-33. PMID 24895337 DOI: 10.3324/haematol.2013.099515  0.553
2014 Snauwaert S, Verstichel G, Bonte S, Goetgeluk G, Vanhee S, Van Caeneghem Y, De Mulder K, Heirman C, Stauss H, Heemskerk MH, Taghon T, Leclercq G, Plum J, Langerak AW, Thielemans K, et al. In vitro generation of mature, naive antigen-specific CD8(+) T cells with a single T-cell receptor by agonist selection. Leukemia. 28: 830-41. PMID 24091848 DOI: 10.1038/leu.2013.285  0.637
2014 Durinck K, Vanloocke W, Van der Meulen J, van de Walle I, Rondou P, De Bock C, Verhasselt B, Poppe BG, Cools J, Soulier J, Taghon T, Speleman F, Van Vlierberghe P. Transcriptional Antagonism Between the Cooperative Oncogenes TLX1 and NOTCH1 in T-Cell Acute Lymphoblastic Leukemia Blood. 124: 3588-3588. DOI: 10.1182/BLOOD.V124.21.3588.3588  0.701
2013 Van Nuffel A, Ariën KK, Stove V, Schindler M, O'Neill E, Schmökel J, Van de Walle I, Naessens E, Vanderstraeten H, Van Landeghem K, Taghon T, Pulkkinen K, Saksela K, Garcia JV, Fackler OT, et al. Primate lentiviral Nef proteins deregulate T-cell development by multiple mechanisms. Retrovirology. 10: 137. PMID 24237970 DOI: 10.1186/1742-4690-10-137  0.409
2013 Van de Walle I, Waegemans E, De Medts J, De Smet G, De Smedt M, Snauwaert S, Vandekerckhove B, Kerre T, Leclercq G, Plum J, Gridley T, Wang T, Koch U, Radtke F, Taghon T. Specific Notch receptor-ligand interactions control human TCR-αβ/γδ development by inducing differential Notch signal strength. The Journal of Experimental Medicine. 210: 683-97. PMID 23530123 DOI: 10.1084/Jem.20121798  0.605
2013 Filtjens J, Taveirne S, Van Acker A, Van Ammel E, Vanhees M, Kerre T, Taghon T, Vandekerckhove B, Plum J, Leclercq G. Abundant stage-dependent Ly49E expression by liver NK cells is not essential for their differentiation and function. Journal of Leukocyte Biology. 93: 699-711. PMID 23475576 DOI: 10.1189/jlb.0812378  0.335
2013 Van Den Broeck T, Van Ammel E, Delforche M, Taveirne S, Kerre T, Vandekerckhove B, Taghon T, Plum J, Leclercq G. Differential Ly49e expression pathways in resting versus TCR-activated intraepithelial γδ T cells. Journal of Immunology (Baltimore, Md. : 1950). 190: 1982-90. PMID 23338239 DOI: 10.4049/jimmunol.1200354  0.665
2013 Van de Walle I, Waegemans E, De Medts J, De Smet G, De Smedt M, Snauwaert S, Vandekerckhove B, Kerre T, Leclercq G, Plum J, Gridley T, Wang T, Koch U, Radtke F, Taghon T. Specific Notch receptor–ligand interactions control human TCR-ab/gd development by inducing differential Notch signal strength The Journal of Cell Biology. 201: i2-i2. DOI: 10.1083/JCB2011OIA2  0.303
2012 Taghon T, Waegemans E, Van de Walle I. Notch signaling during human T cell development. Current Topics in Microbiology and Immunology. 360: 75-97. PMID 22692833 DOI: 10.1007/82_2012_230  0.69
2012 Van Coppernolle S, Vanhee S, Verstichel G, Snauwaert S, van der Spek A, Velghe I, Sinnesael M, Heemskerk MH, Taghon T, Leclercq G, Plum J, Langerak AW, Kerre T, Vandekerckhove B. Notch induces human T-cell receptor γδ+ thymocytes to differentiate along a parallel, highly proliferative and bipotent CD4 CD8 double-positive pathway. Leukemia. 26: 127-38. PMID 22051534 DOI: 10.1038/leu.2011.324  0.579
2011 Klinakis A, Lobry C, Abdel-Wahab O, Oh P, Haeno H, Buonamici S, van De Walle I, Cathelin S, Trimarchi T, Araldi E, Liu C, Ibrahim S, Beran M, Zavadil J, Efstratiadis A, ... Taghon T, et al. A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia. Nature. 473: 230-3. PMID 21562564 DOI: 10.1038/Nature09999  0.471
2011 Taveirne S, De Colvenaer V, Van Den Broeck T, Van Ammel E, Bennett CL, Taghon T, Vandekerckhove B, Plum J, Clausen BE, Kaplan DH, Leclercq G. Langerhans cells are not required for epidermal Vgamma3 T cell homeostasis and function. Journal of Leukocyte Biology. 90: 61-8. PMID 21486908 DOI: 10.1189/jlb.1010581  0.627
2011 Van de Walle I, De Smet G, Gärtner M, De Smedt M, Waegemans E, Vandekerckhove B, Leclercq G, Plum J, Aster JC, Bernstein ID, Guidos CJ, Kyewski B, Taghon T. Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions. Blood. 117: 4449-59. PMID 21372153 DOI: 10.1182/blood-2010-06-290049  0.417
2011 De Smedt M, Leclercq G, Vandekerckhove B, Kerre T, Taghon T, Plum J. T-lymphoid differentiation potential measured in vitro is higher in CD34+CD38-/lo hematopoietic stem cells from umbilical cord blood than from bone marrow and is an intrinsic property of the cells. Haematologica. 96: 646-54. PMID 21330325 DOI: 10.3324/haematol.2010.036343  0.456
2011 De Colvenaer V, Taveirne S, Delforche M, De Smedt M, Vandekerckhove B, Taghon T, Boon L, Plum J, Leclercq G. CD27-deficient mice show normal NK-cell differentiation but impaired function upon stimulation. Immunology and Cell Biology. 89: 803-11. PMID 21283110 DOI: 10.1038/icb.2010.171  0.33
2011 Vandekerckhove B, Vanhee S, Van Coppernolle S, Snauwaert S, Velghe I, Taghon T, Leclercq G, Kerre T, Plum J. In vitro generation of immune cells from pluripotent stem cells. Frontiers in Bioscience (Landmark Edition). 16: 1488-504. PMID 21196243 DOI: 10.2741/3800  0.417
2011 Meuwissen P, Ariën K, Vandewalle I, Naessens E, Vanderstraeten H, Taghon T, Vanham G, Fackler O, Kirchhoff F, Saksela K, Verhasselt B. Nef interferes with development of thymic T cell precursors: differential mechanisms in HIV and SIV Retrovirology. 8. DOI: 10.1186/1742-4690-8-S2-P48  0.358
2011 Van der Meulen J, Mets E, Mestdagh P, Pipelers P, Taghon T, Trujillo DC, Avran D, Van Peer G, Van Roy N, Thas O, Benoit Y, Vandesompele J, Poppe B, Van Vlierberghe P, Rondou P, et al. Regulatory Networks Governed by MicroRNAs in T-ALL Oncogenesis and Normal T-Cell Development Blood. 118: 1366-1366. DOI: 10.1182/BLOOD.V118.21.1366.1366  0.585
2011 Mavrakis KJ, Van Der Meulen J, Wolfe AL, Liu X, Mets E, Taghon T, Khan AA, Setti M, Rondou P, Vandenberghe P, Delabesse E, Benoit Y, Socci NB, Leslie CS, Van Vlierberghe P, et al. Erratum: Corrigendum: A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL) Nature Genetics. 43: 815-815. DOI: 10.1038/NG0811-815B  0.555
2010 Van Vlierberghe P, Palomero T, Khiabanian H, Van der Meulen J, Castillo M, Van Roy N, De Moerloose B, Philippé J, González-García S, Toribio ML, Taghon T, Zuurbier L, Cauwelier B, Harrison CJ, Schwab C, et al. PHF6 mutations in T-cell acute lymphoblastic leukemia. Nature Genetics. 42: 338-42. PMID 20228800 DOI: 10.1038/Ng.542  0.515
2010 De Colvenaer V, Taveirne S, Hamann J, de Bruin AM, De Smedt M, Taghon T, Vandekerckhove B, Plum J, van Lier R, Leclercq G. Continuous CD27 triggering in vivo strongly reduces NK cell numbers. European Journal of Immunology. 40: 1107-17. PMID 20140903 DOI: 10.1002/eji.200939251  0.306
2009 Van Coppernolle S, Verstichel G, Timmermans F, Velghe I, Vermijlen D, De Smedt M, Leclercq G, Plum J, Taghon T, Vandekerckhove B, Kerre T. Functionally mature CD4 and CD8 TCRalphabeta cells are generated in OP9-DL1 cultures from human CD34+ hematopoietic cells. Journal of Immunology (Baltimore, Md. : 1950). 183: 4859-70. PMID 19801512 DOI: 10.4049/jimmunol.0900714  0.471
2009 Timmermans F, Velghe I, Vanwalleghem L, De Smedt M, Van Coppernolle S, Taghon T, Moore HD, Leclercq G, Langerak AW, Kerre T, Plum J, Vandekerckhove B. Generation of T cells from human embryonic stem cell-derived hematopoietic zones. Journal of Immunology (Baltimore, Md. : 1950). 182: 6879-88. PMID 19454684 DOI: 10.4049/jimmunol.0803670  0.545
2009 Van de Walle I, De Smet G, De Smedt M, Vandekerckhove B, Leclercq G, Plum J, Taghon T. An early decrease in Notch activation is required for human TCR-alphabeta lineage differentiation at the expense of TCR-gammadelta T cells. Blood. 113: 2988-98. PMID 19056690 DOI: 10.1182/blood-2008-06-164871  0.71
2009 Taghon T, Van de Walle I, De Smet G, De Smedt M, Leclercq G, Vandekerckhove B, Plum J. Notch signaling is required for proliferation but not for differentiation at a well-defined beta-selection checkpoint during human T-cell development. Blood. 113: 3254-63. PMID 18948571 DOI: 10.1182/blood-2008-07-168906  0.454
2009 Van Coppernolle S, Vandekerckhove B, Verstichel G, Velghe I, Taghon T, Leclercq G, Plum J, Kerre TCC. CD4 and CD8 TCRαβ Cells Are selected On MHC Expressed On Thymocyte Precursors in OP9-DL1 Cultures. Blood. 114: 3670-3670. DOI: 10.1182/BLOOD.V114.22.3670.3670  0.463
2008 Taghon T, Rothenberg EV. Molecular mechanisms that control mouse and human TCR-alphabeta and TCR-gammadelta T cell development. Seminars in Immunopathology. 30: 383-98. PMID 18925397 DOI: 10.1007/S00281-008-0134-3  0.795
2008 Plum J, De Smedt M, Leclercq G, Taghon T, Kerre T, Vandekerckhove B. Human intrathymic development: a selective approach. Seminars in Immunopathology. 30: 411-23. PMID 18925396 DOI: 10.1007/s00281-008-0135-2  0.497
2008 Van Vlierberghe P, Poppe B, Van Roy N, Taghon T, Plum J, Cauwelier B, Selleslag DL, Heimann P, Vandenberghe P, Dastugue N, Delabesse E, Gervais C, Gregoire M, Mozzicconacci M, Lefebvre C, et al. MicroRNA signatures in Genetic Subtypes of T-Cell Acute Lymphoblastic Leukemia. Blood. 112: 3360-3360. DOI: 10.1182/BLOOD.V112.11.3360.3360  0.346
2008 Timmermans F, Velghe I, Van Walleghem L, De Smedt M, Van Coppernolle S, Leclercq G, Taghon T, Moore H, Langerak AW, Kerre TCC, Plum J, Vandekerckhove B. Generation of T Cells from Human Embryonic Stem Cells. Blood. 112: 1527-1527. DOI: 10.1182/BLOOD.V112.11.1527.1527  0.611
2007 De Smedt M, Taghon T, Van de Walle I, De Smet G, Leclercq G, Plum J. Notch signaling induces cytoplasmic CD3 epsilon expression in human differentiating NK cells. Blood. 110: 2696-703. PMID 17630354 DOI: 10.1182/blood-2007-03-082206  0.422
2007 Taghon T, Yui MA, Rothenberg EV. Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3. Nature Immunology. 8: 845-55. PMID 17603486 DOI: 10.1038/Ni1486  0.86
2007 Tydell CC, David-Fung ES, Moore JE, Rowen L, Taghon T, Rothenberg EV. Molecular dissection of prethymic progenitor entry into the T lymphocyte developmental pathway. Journal of Immunology (Baltimore, Md. : 1950). 179: 421-38. PMID 17579063 DOI: 10.4049/Jimmunol.179.1.421  0.644
2007 Smits K, De Smedt M, Naessens E, De Smet G, Stove V, Taghon T, Plum J, Verhasselt B. Tumor necrosis factor promotes T-cell at the expense of B-cell lymphoid development from cultured human CD34+ cord blood cells. Experimental Hematology. 35: 1272-8. PMID 17553612 DOI: 10.1016/j.exphem.2007.04.009  0.382
2006 Franco CB, Scripture-Adams DD, Proekt I, Taghon T, Weiss AH, Yui MA, Adams SL, Diamond RA, Rothenberg EV. Notch/Delta signaling constrains reengineering of pro-T cells by PU.1. Proceedings of the National Academy of Sciences of the United States of America. 103: 11993-8. PMID 16880393 DOI: 10.1073/Pnas.0601188103  0.699
2006 David-Fung ES, Yui MA, Morales M, Wang H, Taghon T, Diamond RA, Rothenberg EV. Progression of regulatory gene expression states in fetal and adult pro-T-cell development. Immunological Reviews. 209: 212-36. PMID 16448545 DOI: 10.1111/J.0105-2896.2006.00355.X  0.729
2006 Taghon T, Yui MA, Pant R, Diamond RA, Rothenberg EV. Developmental and molecular characterization of emerging beta- and gammadelta-selected pre-T cells in the adult mouse thymus. Immunity. 24: 53-64. PMID 16413923 DOI: 10.1016/J.Immuni.2005.11.012  0.778
2005 Rothenberg EV, Taghon T. Molecular genetics of T cell development. Annual Review of Immunology. 23: 601-49. PMID 15771582 DOI: 10.1146/Annurev.Immunol.23.021704.115737  0.831
2003 Taghon T, Thys K, De Smedt M, Weerkamp F, Staal FJ, Plum J, Leclercq G. Homeobox gene expression profile in human hematopoietic multipotent stem cells and T-cell progenitors: implications for human T-cell development. Leukemia. 17: 1157-63. PMID 12764384 DOI: 10.1038/sj.leu.2402947  0.627
2002 De Smedt M, Reynvoet K, Kerre T, Taghon T, Verhasselt B, Vandekerckhove B, Leclercq G, Plum J. Active form of Notch imposes T cell fate in human progenitor cells. Journal of Immunology (Baltimore, Md. : 1950). 169: 3021-9. PMID 12218117  0.599
2002 Taghon T, Stolz F, De Smedt M, Cnockaert M, Verhasselt B, Plum J, Leclercq G. HOX-A10 regulates hematopoietic lineage commitment: evidence for a monocyte-specific transcription factor. Blood. 99: 1197-204. PMID 11830466  0.437
2001 Taghon T, De Smedt M, Stolz F, Cnockaert M, Plum J, Leclercq G. Enforced expression of GATA-3 severely reduces human thymic cellularity. Journal of Immunology (Baltimore, Md. : 1950). 167: 4468-75. PMID 11591773 DOI: 10.4049/jimmunol.167.8.4468  0.691
2000 De Creus A, Van Beneden K, Taghon T, Stolz F, Debacker V, Plum J, Leclercq G. Langerhans Cells That Have Matured In Vivo in the Absence of T Cells Are Fully Capable of Inducing a Helper CD4 as Well as a Cytotoxic CD8 Response The Journal of Immunology. 165: 645-653. DOI: 10.4049/jimmunol.165.2.645  0.427
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