Kannan Kunchithapautham - Publications

Affiliations: 
2004-2015 Intrexon 

25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Coughlin B, Schnabolk G, Joseph K, Raikwar H, Kunchithapautham K, Johnson K, Moore K, Wang Y, Rohrer B. Connecting the innate and adaptive immune responses in mouse choroidal neovascularization via the anaphylatoxin C5a and γδT-cells. Scientific Reports. 6: 23794. PMID 27029558 DOI: 10.1038/Srep23794  0.716
2015 Fields MA, Cai H, Bowrey HE, Moreira EF, Beck Gooz M, Kunchithapautham K, Gong J, Vought E, Del Priore LV. Nitrite Modification of Extracellular Matrix Alters CD46 Expression and VEGF Release in Human Retinal Pigment Epithelium. Investigative Ophthalmology & Visual Science. 56: 4231-8. PMID 26161984 DOI: 10.1167/Iovs.15-16438  0.368
2015 Schnabolk G, Coughlin B, Joseph K, Kunchithapautham K, Bandyopadhyay M, O'Quinn EC, Nowling T, Rohrer B. Local production of the alternative pathway component factor B is sufficient to promote laser-induced choroidal neovascularization. Investigative Ophthalmology & Visual Science. 56: 1850-63. PMID 25593023 DOI: 10.1167/Iovs.14-15910  0.744
2014 Schnabolk G, Stauffer K, O'Quinn E, Coughlin B, Kunchithapautham K, Rohrer B. A comparative analysis of C57BL/6J and 6N substrains; chemokine/cytokine expression and susceptibility to laser-induced choroidal neovascularization. Experimental Eye Research. 129: 18-23. PMID 25305577 DOI: 10.1016/J.Exer.2014.10.005  0.731
2014 Kunchithapautham K, Atkinson C, Rohrer B. Smoke exposure causes endoplasmic reticulum stress and lipid accumulation in retinal pigment epithelium through oxidative stress and complement activation. The Journal of Biological Chemistry. 289: 14534-46. PMID 24711457 DOI: 10.1074/Jbc.M114.564674  0.647
2014 Rohrer B, Kunchithapautham K, Genewsky A, Strauß O. Prolonged SRC kinase activation, a mechanism to turn transient, sublytic complement activation into a sustained pathological condition in retinal pigment epithelium cells. Advances in Experimental Medicine and Biology. 801: 221-7. PMID 24664702 DOI: 10.1007/978-1-4614-3209-8_29  0.664
2013 Woodell A, Coughlin B, Kunchithapautham K, Casey S, Williamson T, Ferrell WD, Atkinson C, Jones BW, Rohrer B. Alternative complement pathway deficiency ameliorates chronic smoke-induced functional and morphological ocular injury. Plos One. 8: e67894. PMID 23825688 DOI: 10.1371/Journal.Pone.0067894  0.744
2013 Joseph K, Kulik L, Coughlin B, Kunchithapautham K, Bandyopadhyay M, Thiel S, Thielens NM, Holers VM, Rohrer B. Oxidative stress sensitizes retinal pigmented epithelial (RPE) cells to complement-mediated injury in a natural antibody-, lectin pathway-, and phospholipid epitope-dependent manner. The Journal of Biological Chemistry. 288: 12753-65. PMID 23493397 DOI: 10.1074/Jbc.M112.421891  0.683
2012 Kunchithapautham K, Bandyopadhyay M, Dahrouj M, Thurman JM, Rohrer B. Sublytic membrane-attack-complex activation and VEGF secretion in retinal pigment epithelial cells. Advances in Experimental Medicine and Biology. 723: 23-30. PMID 22183311 DOI: 10.1007/978-1-4614-0631-0_4  0.662
2012 Rohrer B, Kunchithapautham K, Genewski A, Strauss O. Prolonged voltage-gated calcium channel activation by sublytic complement activation in retinal pigment epithelium, a mechanism for controlling VEGF secretion Immunobiology. 217: 1194-1195. DOI: 10.1016/J.Imbio.2012.08.188  0.612
2011 Kunchithapautham K, Rohrer B. Sublytic membrane-attack-complex (MAC) activation alters regulated rather than constitutive vascular endothelial growth factor (VEGF) secretion in retinal pigment epithelium monolayers. The Journal of Biological Chemistry. 286: 23717-24. PMID 21566137 DOI: 10.1074/Jbc.M110.214593  0.643
2011 Kunchithapautham K, Coughlin B, Lemasters JJ, Rohrer B. Differential effects of rapamycin on rods and cones during light-induced stress in albino mice. Investigative Ophthalmology & Visual Science. 52: 2967-75. PMID 21273550 DOI: 10.1167/Iovs.10-6278  0.639
2011 Rohrer B, Coughlin B, Kunchithapautham K, Long Q, Tomlinson S, Takahashi K, Holers VM. The alternative pathway is required, but not alone sufficient, for retinal pathology in mouse laser-induced choroidal neovascularization. Molecular Immunology. 48: e1-8. PMID 21257205 DOI: 10.1016/J.Molimm.2010.12.016  0.672
2010 Rohrer B, Long Q, Coughlin B, Renner B, Huang Y, Kunchithapautham K, Ferreira VP, Pangburn MK, Gilkeson GS, Thurman JM, Tomlinson S, Holers VM. A targeted inhibitor of the complement alternative pathway reduces RPE injury and angiogenesis in models of age-related macular degeneration. Advances in Experimental Medicine and Biology. 703: 137-49. PMID 20711712 DOI: 10.1007/978-1-4419-5635-4_10  0.676
2010 Ogando DG, Dahlquist KD, Alizadeh M, Kunchithapautham K, Li J, Yu N, LaVail MM, Rohrer B, Vollrath D, Danciger M. Candidate genes for chromosomes 6 and 10 quantitative trait loci for age-related retinal degeneration in mice. Molecular Vision. 16: 1004-18. PMID 20577653  0.584
2010 Thurman JM, Renner B, Kunchithapautham K, Holers VM, Rohrer B. Aseptic injury to epithelial cells alters cell surface complement regulation in a tissue specific fashion. Advances in Experimental Medicine and Biology. 664: 151-8. PMID 20238013 DOI: 10.1007/978-1-4419-1399-9_18  0.631
2009 Kunchithapautham K, Coughlin B, Crouch RK, Rohrer B. Cone outer segment morphology and cone function in the Rpe65-/- Nrl-/- mouse retina are amenable to retinoid replacement. Investigative Ophthalmology & Visual Science. 50: 4858-64. PMID 19407011 DOI: 10.1167/Iovs.08-3008  0.626
2009 Thurman JM, Renner B, Kunchithapautham K, Ferreira VP, Pangburn MK, Ablonczy Z, Tomlinson S, Holers VM, Rohrer B. Oxidative stress renders retinal pigment epithelial cells susceptible to complement-mediated injury. The Journal of Biological Chemistry. 284: 16939-47. PMID 19386604 DOI: 10.1074/Jbc.M808166200  0.678
2009 Rohrer B, Long Q, Coughlin B, Wilson RB, Huang Y, Qiao F, Tang PH, Kunchithapautham K, Gilkeson GS, Tomlinson S. A targeted inhibitor of the alternative complement pathway reduces angiogenesis in a mouse model of age-related macular degeneration. Investigative Ophthalmology & Visual Science. 50: 3056-64. PMID 19264882 DOI: 10.1167/Iovs.08-2222  0.651
2008 Rohrer B, Long Q, Wilson B, Coughlin B, Huang Y, Qiao F, Tang P, Kunchithapautham K, Gilkeson G, Tomlinson S. Alternative complement pathway signalling in a mouse model of choroidal neovascularisation Molecular Immunology. 45: 4162. DOI: 10.1016/J.Molimm.2008.08.201  0.599
2008 Rohrer B, Renner B, Kunchithapautham K, Ablonczy Z, Tomlinson S, Thurman J. Oxidative stress renders retinal epithelial cells susceptible to complement mediated injury Molecular Immunology. 45: 4162. DOI: 10.1016/J.Molimm.2008.08.200  0.641
2007 Rohrer B, Guo Y, Kunchithapautham K, Gilkeson GS. Eliminating complement factor D reduces photoreceptor susceptibility to light-induced damage. Investigative Ophthalmology & Visual Science. 48: 5282-9. PMID 17962484 DOI: 10.1167/Iovs.07-0282  0.666
2007 Wilson RB, Kunchithapautham K, Rohrer B. Paradoxical role of BDNF: BDNF+/- retinas are protected against light damage-mediated stress. Investigative Ophthalmology & Visual Science. 48: 2877-86. PMID 17525224 DOI: 10.1167/Iovs.06-1079  0.625
2007 Kunchithapautham K, Rohrer B. Apoptosis and autophagy in photoreceptors exposed to oxidative stress. Autophagy. 3: 433-41. PMID 17471016 DOI: 10.4161/Auto.4294  0.642
2007 Kunchithapautham K, Rohrer B. Autophagy is one of the multiple mechanisms active in photoreceptor degeneration. Autophagy. 3: 65-6. PMID 17102584 DOI: 10.4161/Auto.3431  0.66
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