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Ronald T Javier - Publications

Affiliations: 
Baylor College of Medicine, Houston, TX 
Area:
Adenoviruses and viral oncology
Website:
https://www.bcm.edu/people/view/ronald-javier-ph-d/b2446d1f-ffed-11e2-be68-080027880ca6
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40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Kong K, Kumar M, Taruishi M, Javier RT. Adenovirus E4-ORF1 Dysregulates Epidermal Growth Factor and Insulin/Insulin-like Growth Factor Receptors to Mediate Constitutive Myc Expression. Journal of Virology. PMID 26269183 DOI: 10.1128/Jvi.01463-15  0.457
2014 Kumar M, Kong K, Javier RT. Hijacking Dlg1 for oncogenic phosphatidylinositol 3-kinase activation in human epithelial cells is a conserved mechanism of human adenovirus E4-ORF1 proteins. Journal of Virology. 88: 14268-77. PMID 25253337 DOI: 10.1128/Jvi.02324-14  0.54
2014 Kong K, Kumar M, Taruishi M, Javier RT. The human adenovirus E4-ORF1 protein subverts discs large 1 to mediate membrane recruitment and dysregulation of phosphatidylinositol 3-kinase. Plos Pathogens. 10: e1004102. PMID 24788832 DOI: 10.1371/Journal.Ppat.1004102  0.553
2011 Irvin-Wilson CV, Newberg JY, Kong K, Javier RT, Marriott SJ. High throughput method to quantify anterior-posterior polarity of T-cells and epithelial cells. Viruses. 3: 2396-411. PMID 22355445 DOI: 10.3390/V3122396  0.322
2011 Golebiewski L, Liu H, Javier RT, Rice AP. The avian influenza virus NS1 ESEV PDZ binding motif associates with Dlg1 and Scribble to disrupt cellular tight junctions. Journal of Virology. 85: 10639-48. PMID 21849460 DOI: 10.1128/Jvi.05070-11  0.476
2011 Javier RT, Rice AP. Emerging theme: cellular PDZ proteins as common targets of pathogenic viruses. Journal of Virology. 85: 11544-56. PMID 21775458 DOI: 10.1128/Jvi.05410-11  0.536
2010 Liu H, Golebiewski L, Dow EC, Krug RM, Javier RT, Rice AP. The ESEV PDZ-binding motif of the avian influenza A virus NS1 protein protects infected cells from apoptosis by directly targeting Scribble. Journal of Virology. 84: 11164-74. PMID 20702615 DOI: 10.1128/Jvi.01278-10  0.465
2008 Javier RT. Cell polarity proteins: common targets for tumorigenic human viruses. Oncogene. 27: 7031-46. PMID 19029943 DOI: 10.1038/Onc.2008.352  0.556
2008 Javier RT, Butel JS. The history of tumor virology. Cancer Research. 68: 7693-706. PMID 18829521 DOI: 10.1158/0008-5472.Can-08-3301  0.35
2008 Chung SH, Weiss RS, Frese KK, Prasad BV, Javier RT. Functionally distinct monomers and trimers produced by a viral oncoprotein. Oncogene. 27: 1412-20. PMID 17828302 DOI: 10.1038/Sj.Onc.1210784  0.48
2007 Chung SH, Frese KK, Weiss RS, Prasad BV, Javier RT. A new crucial protein interaction element that targets the adenovirus E4-ORF1 oncoprotein to membrane vesicles. Journal of Virology. 81: 4787-97. PMID 17314165 DOI: 10.1128/Jvi.02855-06  0.545
2007 Gregorc U, Ivanova S, Thomas M, Guccione E, Glaunsinger B, Javier R, Turk V, Banks L, Turk B. Cleavage of MAGI-1, a tight junction PDZ protein, by caspases is an important step for cell-cell detachment in apoptosis. Apoptosis : An International Journal On Programmed Cell Death. 12: 343-54. PMID 17191119 DOI: 10.1007/S10495-006-0579-6  0.576
2006 Frese KK, Latorre IJ, Chung SH, Caruana G, Bernstein A, Jones SN, Donehower LA, Justice MJ, Garner CC, Javier RT. Oncogenic function for the Dlg1 mammalian homolog of the Drosophila discs-large tumor suppressor. The Embo Journal. 25: 1406-17. PMID 16511562 DOI: 10.1038/Sj.Emboj.7601030  0.5
2005 Latorre IJ, Roh MH, Frese KK, Weiss RS, Margolis B, Javier RT. Viral oncoprotein-induced mislocalization of select PDZ proteins disrupts tight junctions and causes polarity defects in epithelial cells. Journal of Cell Science. 118: 4283-93. PMID 16141229 DOI: 10.1242/Jcs.02560  0.523
2003 Frese KK, Lee SS, Thomas DL, Latorre IJ, Weiss RS, Glaunsinger BA, Javier RT. Selective PDZ protein-dependent stimulation of phosphatidylinositol 3-kinase by the adenovirus E4-ORF1 oncoprotein. Oncogene. 22: 710-21. PMID 12569363 DOI: 10.1038/Sj.Onc.1206151  0.715
2002 Kimber WA, Trinkle-Mulcahy L, Cheung PCF, Deak M, Marsden LJ, Kieloch A, Watt S, Javier RT, Gray A, Downes CP, Lucocq JM, Alessi DR. Evidence that the tandem-pleckstrin-homology-domain-containing protein TAPP1 interacts with Ptd(3,4)P2 and the multi-PDZ-domain-containing protein MUPP1 in vivo Biochemical Journal. 361: 525-536. PMID 11802782 DOI: 10.1042/0264-6021:3610525  0.412
2001 Glaunsinger BA, Weiss RS, Lee SS, Javier R. Link of the unique oncogenic properties of adenovirus type 9 E4-ORF1 to a select interaction with the candidate tumor suppressor protein ZO-2 Embo Journal. 20: 5578-5586. PMID 11598001 DOI: 10.1093/Emboj/20.20.5578  0.71
2001 Thomas M, Glaunsinger B, Pim D, Javier R, Banks L. HPV E6 and MAGUK protein interactions: Determination of the molecular basis for specific protein recognition and degradation Oncogene. 20: 5431-5439. PMID 11571640 DOI: 10.1038/Sj.Onc.1204719  0.682
2001 Thomas DL, Schaack J, Vogel H, Javier R. Several E4 region functions influence mammary tumorigenesis by human adenovirus type 9. Journal of Virology. 75: 557-68. PMID 11134268 DOI: 10.1128/Jvi.75.2.557-568.2001  0.49
2000 Glaunsinger BA, Lee SS, Thomas M, Banks L, Javier R. Interactions of the PDZ-protein MAGI-1 with adenovirus E4-ORF1 and high-risk papillomavirus E6 oncoproteins Oncogene. 19: 5270-5280. PMID 11077444 DOI: 10.1038/Sj.Onc.1203906  0.729
2000 Lee SS, Glaunsinger B, Mantovani F, Banks L, Javier RT. Multi-PDZ domain protein MUPP1 is a cellular target for both adenovirus E4-ORF1 and high-risk papillomavirus type 18 E6 oncoproteins Journal of Virology. 74: 9680-9693. PMID 11000240 DOI: 10.1128/Jvi.74.20.9680-9693.2000  0.73
2000 Barritt DS, Pearn MT, Zisch AH, Lee SS, Javier RT, Pasquale EB, Stallcup WB. The multi-PDZ domain protein MUPP1 is a cytoplasmic ligand for the membrane-spanning proteoglycan NG2. Journal of Cellular Biochemistry. 79: 213-24. PMID 10967549 DOI: 10.1002/1097-4644(20001101)79:2<213::Aid-Jcb50>3.0.Co;2-G  0.391
2000 Pim D, Thomas M, Javier R, Gardiol D, Banks L. HPV E6 targeted degradation of the discs large protein: evidence for the involvement of a novel ubiquitin ligase. Oncogene. 19: 719-25. PMID 10698489 DOI: 10.1038/sj.onc.1203374  0.43
1999 Gardiol D, Kühne C, Glaunsinger B, Lee SS, Javier R, Banks L. Oncogenic human papillomavirus E6 proteins target the discs large tumour suppressor for proteasome mediated degradation Oncogene. 18: 5487-5496. PMID 10523825 DOI: 10.1038/Sj.Onc.1202920  0.693
1999 Thomas DL, Shin S, Jiang BH, Vogel H, Ross MA, Kaplitt M, Shenk TE, Javier RT. Early region 1 transforming functions are dispensable for mammary tumorigenesis by human adenovirus type 9. Journal of Virology. 73: 3071-9. PMID 10074157 DOI: 10.1128/Jvi.73.4.3071-3079.1999  0.465
1999 Thomas DL, Shin S, Jiang BH, Vogel H, Ross MA, Kaplitt M, Shenk TE, Javier RT. Early Region 1 Transforming Functions Are Dispensable for Mammary Tumorigenesis by Human Adenovirus Type 9 Journal of Virology. 73: 3071-3079. DOI: 10.1128/jvi.73.4.3071-3079.1999  0.371
1997 Weiss RS, Javier RT. A carboxy-terminal region required by the adenovirus type 9 E4 ORF1 oncoprotein for transformation mediates direct binding to cellular polypeptides. Journal of Virology. 71: 7873-80. PMID 9311876  0.426
1997 Lee SS, Weiss RS, Javier RT. Binding of human virus oncoproteins to hDlg/SAP97, a mammalian homolog of the Drosophila discs large tumor suppressor protein. Proceedings of the National Academy of Sciences of the United States of America. 94: 6670-5. PMID 9192623 DOI: 10.1073/Pnas.94.13.6670  0.551
1997 Weiss RS, Gold MO, Vogel H, Javier RT. Mutant adenovirus type 9 E4 ORF1 genes define three protein regions required for transformation of CREF cells. Journal of Virology. 71: 4385-94. PMID 9151828 DOI: 10.1128/Jvi.71.6.4385-4394.1997  0.475
1997 Weiss RS, Lee SS, Prasad BV, Javier RT. Human adenovirus early region 4 open reading frame 1 genes encode growth-transforming proteins that may be distantly related to dUTP pyrophosphatase enzymes. Journal of Virology. 71: 1857-70. PMID 9032316 DOI: 10.1128/Jvi.71.3.1857-1870.1997  0.549
1996 Javier R, Shenk T. Mammary tumors induced by human adenovirus type 9: A role for the viral early region 4 gene Breast Cancer Research and Treatment. 39: 57-67. PMID 8738606 DOI: 10.1007/Bf01806078  0.411
1996 Weiss RS, McArthur MJ, Javier RT. Human adenovirus type 9 E4 open reading frame 1 encodes a cytoplasmic transforming protein capable of increasing the oncogenicity of CREF cells. Journal of Virology. 70: 862-72. PMID 8551625 DOI: 10.1128/Jvi.70.2.862-872.1996  0.482
1994 Javier RT. Adenovirus type 9 E4 open reading frame 1 encodes a transforming protein required for the production of mammary tumors in rats. Journal of Virology. 68: 3917-24. PMID 8189528 DOI: 10.1128/Jvi.68.6.3917-3924.1994  0.503
1992 Javier R, Raska K, Shenk T. Requirement for the adenovirus type 9 E4 region in production of mammary tumors Science. 257: 1267-1270. PMID 1519063 DOI: 10.1126/Science.1519063  0.35
1990 Hill JM, Sedarati F, Javier RT, Wagner EK, Stevens JG. Herpes simplex virus latent phase transcription facilitates in vivo reactivation. Virology. 174: 117-25. PMID 2152989 DOI: 10.1016/0042-6822(90)90060-5  0.524
1988 Javier RT, Stevens JG, Dissette VB, Wagner EK. A herpes simplex virus transcript abundant in latently infected neurons is dispensable for establishment of the latent state. Virology. 166: 254-7. PMID 2842950 DOI: 10.1016/0042-6822(88)90169-9  0.544
1988 Sedarati F, Javier RT, Stevens JG. Pathogenesis of a lethal mixed infection in mice with two nonneuroinvasive herpes simplex virus strains. Journal of Virology. 62: 3037-9. PMID 2839719 DOI: 10.1128/Jvi.62.8.3037-3039.1988  0.523
1988 Javier RT, Izumi KM, Stevens JG. Localization of a herpes simplex virus neurovirulence gene dissociated from high-titer virus replication in the brain. Journal of Virology. 62: 1381-7. PMID 2831400 DOI: 10.1128/Jvi.62.4.1381-1387.1988  0.53
1987 Javier RT, Thompson RL, Stevens JG. Genetic and biological analyses of a herpes simplex virus intertypic recombinant reduced specifically for neurovirulence. Journal of Virology. 61: 1978-84. PMID 3033324 DOI: 10.1128/Jvi.61.6.1978-1984.1987  0.527
1986 Javier RT, Sedarati F, Stevens JG. Two avirulent herpes simplex viruses generate lethal recombinants in vivo. Science (New York, N.Y.). 234: 746-8. PMID 3022376 DOI: 10.1126/Science.3022376  0.531
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