Matthew Merrins - Publications

Affiliations: 
University of Wisconsin, Madison, Madison, WI 

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Knuth ER, Foster HR, Jin E, Ekstrand MH, Knudsen JG, Merrins MJ. Leucine suppresses α-cell cAMP and glucagon secretion via a combination of cell-intrinsic and islet paracrine signaling. Diabetes. PMID 38870025 DOI: 10.2337/db23-1013  0.352
2024 Merrins MJ, Kibbey RG. Glucose Regulation of β-Cell KATP Channels: It Is Time for a New Model! Diabetes. 73: 856-863. PMID 38768366 DOI: 10.2337/dbi23-0032  0.346
2024 Cuozzo F, Viloria K, Shilleh AH, Nasteska D, Frazer-Morris C, Tong J, Jiao Z, Boufersaoui A, Marzullo B, Rosoff DB, Smith HR, Bonner C, Kerr-Conte J, Pattou F, Nano R, ... ... Merrins MJ, et al. LDHB contributes to the regulation of lactate levels and basal insulin secretion in human pancreatic β cells. Cell Reports. 43: 114047. PMID 38607916 DOI: 10.1016/j.celrep.2024.114047  0.355
2023 Emfinger CH, Clark LE, Yandell B, Schueler KL, Simonett SP, Stapleton DS, Mitok KA, Merrins MJ, Keller MP, Attie AD. Novel regulators of islet function identified from genetic variation in mouse islet Ca oscillations. Elife. 12. PMID 37787501 DOI: 10.7554/eLife.88189  0.405
2023 Knuth ER, Foster HR, Jin E, Merrins MJ. Leucine suppresses glucagon secretion from pancreatic islets by directly modulating α-cell cAMP. Biorxiv : the Preprint Server For Biology. PMID 37577685 DOI: 10.1101/2023.07.31.551113  0.338
2023 Schaid MD, Harrington JM, Kelly GM, Sdao SM, Merrins MJ, Kimple ME. EP3 signaling is decoupled from the regulation of glucose-stimulated insulin secretion in β-cells compensating for obesity and insulin resistance. Islets. 15: 2223327. PMID 37415404 DOI: 10.1080/19382014.2023.2223327  0.42
2023 Xu W, Qadir MMF, Nasteska D, Mota de Sa P, Gorvin CM, Blandino-Rosano M, Evans CR, Ho T, Potapenko E, Veluthakal R, Ashford FB, Bitsi S, Fan J, Bhondeley M, Song K, ... ... Merrins MJ, et al. Architecture of androgen receptor pathways amplifying glucagon-like peptide-1 insulinotropic action in male pancreatic β cells. Cell Reports. 42: 112529. PMID 37200193 DOI: 10.1016/j.celrep.2023.112529  0.305
2022 Foster HR, Ho T, Potapenko E, Sdao SM, Huang SM, Lewandowski SL, VanDeusen HR, Davidson SM, Cardone RL, Prentki M, Kibbey RG, Merrins MJ. β-cell deletion of the PKm1 and PKm2 isoforms of pyruvate kinase in mice reveal their essential role as nutrient sensors for the K channel. Elife. 11. PMID 35997256 DOI: 10.7554/eLife.79422  0.305
2022 Merrins MJ, Corkey BE, Kibbey RG, Prentki M. Metabolic cycles and signals for insulin secretion. Cell Metabolism. PMID 35728586 DOI: 10.1016/j.cmet.2022.06.003  0.354
2022 Emfinger CH, de Klerk E, Schueler KL, Rabaglia ME, Stapleton DS, Simonett SP, Mitok KA, Wang Z, Liu X, Paulo JA, Yu Q, Cardone RL, Foster HR, Lewandowski SL, Perales JC, ... ... Merrins MJ, et al. β Cell-specific deletion of Zfp148 improves nutrient-stimulated β cell Ca2+ responses. Jci Insight. 7. PMID 35603790 DOI: 10.1172/jci.insight.154198  0.434
2021 Corkey BE, Deeney JT, Merrins MJ. What Regulates Basal Insulin Secretion and Causes Hyperinsulinemia? Diabetes. 70: 2174-2182. PMID 34593535 DOI: 10.2337/dbi21-0009  0.341
2021 Lin H, Smith N, Spigelman AF, Suzuki K, Ferdaoussi M, Alghamdi TA, Lewandowski SL, Jin Y, Bautista A, Wang YW, Manning Fox JE, Merrins MJ, Buteau J, MacDonald PE. β-Cell Knockout of SENP1 Reduces Responses to Incretins and Worsens Oral Glucose Tolerance in High Fat Diet-Fed Mice. Diabetes. PMID 34462260 DOI: 10.2337/db20-1235  0.338
2021 Adams MT, Dwulet JM, Briggs JK, Reissaus CA, Jin E, Szulczewski JM, Lyman MR, Sdao SM, Kravets V, Nimkulrat SD, Ponik SM, Merrins MJ, Mirmira RG, Linnemann AK, Benninger RK, et al. Reduced synchroneity of intra-islet Ca oscillations in -deficient β cells. Elife. 10. PMID 34231467 DOI: 10.7554/eLife.61308  0.403
2021 El K, Gray SM, Capozzi ME, Knuth ER, Jin E, Svendsen B, Clifford A, Brown JL, Encisco SE, Chazotte BM, Sloop KW, Nunez DJ, Merrins MJ, D'Alessio DA, Campbell JE. GIP mediates the incretin effect and glucose tolerance by dual actions on α cells and β cells. Science Advances. 7. PMID 33712466 DOI: 10.1126/sciadv.abf1948  0.337
2021 Sdao SM, Ho T, Poudel C, Foster HR, De Leon ER, Adams MT, Lee JH, Blum B, Rane SG, Merrins MJ. CDK2 limits the highly energetic secretory program of mature β cells by restricting PEP cycle-dependent K channel closure. Cell Reports. 34: 108690. PMID 33503433 DOI: 10.1016/j.celrep.2021.108690  0.377
2020 Abulizi A, Cardone RL, Stark R, Lewandowski SL, Zhao X, Hillion J, Ma L, Sehgal R, Alves TC, Thomas C, Kung C, Wang B, Siebel S, Andrews ZB, Mason GF, ... ... Merrins MJ, et al. Multi-Tissue Acceleration of the Mitochondrial Phosphoenolpyruvate Cycle Improves Whole-Body Metabolic Health. Cell Metabolism. 32: 751-766.e11. PMID 33147485 DOI: 10.1016/j.cmet.2020.10.006  0.35
2020 Lewandowski SL, Cardone RL, Foster HR, Ho T, Potapenko E, Poudel C, VanDeusen HR, Sdao SM, Alves TC, Zhao X, Capozzi ME, de Souza AH, Jahan I, Thomas CJ, Nunemaker CS, ... ... Merrins MJ, et al. Pyruvate Kinase Controls Signal Strength in the Insulin Secretory Pathway. Cell Metabolism. 32: 736-750.e5. PMID 33147484 DOI: 10.1016/j.cmet.2020.10.007  0.404
2020 de Souza AH, Tang J, Yadev AK, Saghafi ST, Kibbe CR, Linnemann AK, Merrins MJ, Davis DB. Intra-islet GLP-1, but not CCK, is necessary for β-cell function in mouse and human islets. Scientific Reports. 10: 2823. PMID 32071395 DOI: 10.1038/S41598-020-59799-2  0.329
2019 Douros JD, Niu J, Sdao SM, Gregg T, Fisher-Wellman KH, Bharadwaj MS, Molina A, Arumugam R, Martin MD, Petretto E, Merrins MJ, Herman MA, Tong J, Campbell JE, D'Alessio D. Sleeve gastrectomy rapidly enhances islet function independently of body weight. Jci Insight. PMID 30777938 DOI: 10.1172/Jci.Insight.126688  0.304
2019 Capozzi ME, Svendsen B, Encisco SE, Lewandowski SL, Martin MD, Lin H, Jaffe JL, Coch RW, Haldeman JM, MacDonald PE, Merrins MJ, D'Alessio DA, Campbell JE. β-Cell tone is defined by proglucagon peptides through cyclic AMP signaling. Jci Insight. PMID 30720465 DOI: 10.1172/jci.insight.126742  0.362
2019 Gregg T, Sdao SM, Dhillon RS, Rensvold JW, Lewandowski SL, Pagliarini DJ, Denu JM, Merrins MJ. Obesity-dependent CDK1 signaling stimulates mitochondrial respiration at complex I in pancreatic β-cells. The Journal of Biological Chemistry. PMID 30700550 DOI: 10.1074/Jbc.Ra118.006085  0.355
2018 Hennings TG, Chopra DG, DeLeon ER, VanDeusen HR, Sesaki H, Merrins MJ, Ku GM. In vivo Deletion of Beta Cell Drp1 Impairs Insulin Secretion without Affecting Islet Oxygen Consumption. Endocrinology. PMID 30052866 DOI: 10.1210/En.2018-00445  0.395
2017 Hernandez R, Graves SA, Gregg T, VanDeusen HR, Fenske RJ, Wienkes HN, England CG, Valdovinos HF, Jeffery JJ, Barnhart TE, Severin GW, Nickles RJ, Kimple ME, Merrins MJ, Cai W. Radiomanganese PET Detects Changes in Functional β-cell Mass in Mouse Models of Diabetes. Diabetes. PMID 28515126 DOI: 10.2337/Db16-1285  0.323
2017 Neuman JC, Schaid MD, Brill AL, Fenske RJ, Kibbe CR, Fontaine DA, Sdao SM, Brar HK, Connors KM, Wienkes HN, Eliceiri KW, Merrins MJ, Davis DB, Kimple ME. Enriching Islet Phospholipids with Eicosapentaenoic Acid Reduces Prostaglandin E2 Signaling and Enhances Diabetic β-cell Function. Diabetes. PMID 28193789 DOI: 10.2337/Db16-1362  0.324
2017 Kim SY, Lee JH, Merrins MJ, Gavrilova O, Bisteau X, Kaldis P, Satin LS, Rane SG. Loss of Cyclin Dependent Kinase 2 in the Pancreas Links Primary β-cell Dysfunction to Progressive Depletion of β-cell Mass and Diabetes. The Journal of Biological Chemistry. PMID 28100774 DOI: 10.1074/jbc.M116.754077  0.564
2016 Gregg T, Poudel C, Schmidt BA, Dhillon RS, Sdao SM, Truchan NA, Baar EL, Fernandez LA, Denu JM, Eliceiri KW, Rogers JD, Kimple ME, Lamming DW, Merrins MJ. Pancreatic β cells from Mice Offset Age-Associated Mitochondrial Deficiency with Reduced KATP Channel Activity. Diabetes. PMID 27284112 DOI: 10.2337/Db16-0432  0.392
2016 Wynn ML, Yates JA, Evans CR, Van Wassenhove L, Wu ZF, Bridges S, Bao L, Fournier C, Ashrafzadeh S, Merrins MJ, Satin LS, Schnell S, Burant CF, Merajver SD. RhoC is a Potent Regulator of Glutamine Metabolism and N-acetylaspartate Production in Inflammatory Breast Cancer Cells. The Journal of Biological Chemistry. PMID 27129239 DOI: 10.1074/Jbc.M115.703959  0.506
2016 McKenna JP, Ha J, Merrins MJ, Satin LS, Sherman A, Bertram R. Ca(2+) Effects on ATP Production and Consumption Have Regulatory Roles on Oscillatory Islet Activity. Biophysical Journal. 110: 733-742. PMID 26840737 DOI: 10.1016/J.Bpj.2015.11.3526  0.663
2016 Merrins MJ, Poudel C, McKenna JP, Ha J, Sherman A, Bertram R, Satin LS. Phase Analysis of Metabolic Oscillations and Membrane Potential in Pancreatic Islet β-Cells. Biophysical Journal. 110: 691-699. PMID 26840733 DOI: 10.1016/J.Bpj.2015.12.029  0.655
2016 Lamming D, Cummings N, Arriola Apelo S, Neuman J, Schmidt B, Merrins M, Kimple M, Fontana L. ID: 78: IMPROVING GLYCEMIC CONTROL THROUGH REDUCTION OF SPECIFIC DIETARY AMINO ACIDS Journal of Investigative Medicine. 64: 926.1-926. DOI: 10.1136/Jim-2016-000120.32  0.336
2016 Poudel C, Schmidt BA, Harenda QE, Engin F, Eliceiri KW, Merrins MJ. TUDCA Rescues γ-Cell Metabolic Oscillations from ER Stress, Revealed By NAD(P)H-FLIM and FRET Biophysical Journal. 110: 142a-143a. DOI: 10.1016/J.Bpj.2015.11.810  0.391
2014 Watts M, Fendler B, Merrins MJ, Satin LS, Bertram R, Sherman A. Calcium and Metabolic Oscillations in Pancreatic Islets: Who's Driving the Bus?(*) Siam Journal On Applied Dynamical Systems. 13: 683-703. PMID 25698909 DOI: 10.1137/130920198  0.66
2014 Johnson JS, Kono T, Tong X, Yamamoto WR, Zarain-Herzberg A, Merrins MJ, Satin LS, Gilon P, Evans-Molina C. Pancreatic and duodenal homeobox protein 1 (Pdx-1) maintains endoplasmic reticulum calcium levels through transcriptional regulation of sarco-endoplasmic reticulum calcium ATPase 2b (SERCA2b) in the islet β cell. The Journal of Biological Chemistry. 289: 32798-810. PMID 25271154 DOI: 10.1074/Jbc.M114.575191  0.574
2014 Alejandro EU, Gregg B, Wallen T, Kumusoglu D, Meister D, Chen A, Merrins MJ, Satin LS, Liu M, Arvan P, Bernal-Mizrachi E. Maternal diet-induced microRNAs and mTOR underlie β cell dysfunction in offspring. The Journal of Clinical Investigation. 124: 4395-410. PMID 25180600 DOI: 10.1172/JCI74237  0.581
2014 Merrins MJ, Satin LS. Ca2+ has a Permissive Effect on Glycolytic Oscillations in Pancreatic Beta Cells Biophysical Journal. 106: 526a. DOI: 10.1016/j.bpj.2013.11.2937  0.63
2013 Merrins MJ, Van Dyke AR, Mapp AK, Rizzo MA, Satin LS. Direct measurements of oscillatory glycolysis in pancreatic islet β-cells using novel fluorescence resonance energy transfer (FRET) biosensors for pyruvate kinase M2 activity. The Journal of Biological Chemistry. 288: 33312-22. PMID 24100037 DOI: 10.1074/Jbc.M113.508127  0.611
2013 Merrins MJ, Kim SY, Rane SG, Satin LS. Cyclin Dependent Kinase 2 (CDK2) Regulates Secretory Function in Pancreatic Beta-Cells Biophysical Journal. 104: 621a. DOI: 10.1016/j.bpj.2012.11.3435  0.543
2012 Merrins MJ, Bertram R, Sherman A, Satin LS. Phosphofructo-2-kinase/fructose-2,6-bisphosphatase modulates oscillations of pancreatic islet metabolism. Plos One. 7: e34036. PMID 22532827 DOI: 10.1371/Journal.Pone.0034036  0.67
2012 Merrins MJ, Satin LS. A Novel FRET Biosensor For Measuring Glycolytic Activity: A Study of Pancreatic Beta-Cells Biophysical Journal. 102: 199a. DOI: 10.1016/j.bpj.2011.11.1084  0.556
2011 Merrins M, Bertram R, Sherman A, Satin L. Testing a Computational Model of Pancreatic Beta-Cell Oscillations Using Live-Cell Imaging of Islet Oscillatory Behavior Microscopy and Microanalysis. 17: 208-209. DOI: 10.1017/S1431927611001917  0.599
2011 Merrins MJ, Bertram R, Sherman A, Satin LS. 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase (PFKFB) Modulates Slow Oscillations in Pancreatic Islets Biophysical Journal. 100: 380a-381a. DOI: 10.1016/J.Bpj.2010.12.2265  0.655
2010 Merrins MJ, Fendler B, Zhang M, Sherman A, Bertram R, Satin LS. Metabolic oscillations in pancreatic islets depend on the intracellular Ca2+ level but not Ca2+ oscillations. Biophysical Journal. 99: 76-84. PMID 20655835 DOI: 10.1016/J.Bpj.2010.04.012  0.638
2009 Nunemaker CS, Dishinger JF, Dula SB, Wu R, Merrins MJ, Reid KR, Sherman A, Kennedy RT, Satin LS. Glucose metabolism, islet architecture, and genetic homogeneity in imprinting of [Ca2+](i) and insulin rhythms in mouse islets. Plos One. 4: e8428. PMID 20037650 DOI: 10.1371/Journal.Pone.0008428  0.648
2008 Merrins MJ, Stuenkel EL. Kinetics of Rab27a-dependent actions on vesicle docking and priming in pancreatic beta-cells. The Journal of Physiology. 586: 5367-81. PMID 18801842 DOI: 10.1113/Jphysiol.2008.158477  0.405
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