Year |
Citation |
Score |
2024 |
Knuth ER, Foster HR, Jin E, Ekstrand MH, Knudsen JG, Merrins MJ. Leucine suppresses α-cell cAMP and glucagon secretion via a combination of cell-intrinsic and islet paracrine signaling. Diabetes. PMID 38870025 DOI: 10.2337/db23-1013 |
0.352 |
|
2024 |
Merrins MJ, Kibbey RG. Glucose Regulation of β-Cell KATP Channels: It Is Time for a New Model! Diabetes. 73: 856-863. PMID 38768366 DOI: 10.2337/dbi23-0032 |
0.346 |
|
2024 |
Cuozzo F, Viloria K, Shilleh AH, Nasteska D, Frazer-Morris C, Tong J, Jiao Z, Boufersaoui A, Marzullo B, Rosoff DB, Smith HR, Bonner C, Kerr-Conte J, Pattou F, Nano R, ... ... Merrins MJ, et al. LDHB contributes to the regulation of lactate levels and basal insulin secretion in human pancreatic β cells. Cell Reports. 43: 114047. PMID 38607916 DOI: 10.1016/j.celrep.2024.114047 |
0.355 |
|
2023 |
Emfinger CH, Clark LE, Yandell B, Schueler KL, Simonett SP, Stapleton DS, Mitok KA, Merrins MJ, Keller MP, Attie AD. Novel regulators of islet function identified from genetic variation in mouse islet Ca oscillations. Elife. 12. PMID 37787501 DOI: 10.7554/eLife.88189 |
0.405 |
|
2023 |
Knuth ER, Foster HR, Jin E, Merrins MJ. Leucine suppresses glucagon secretion from pancreatic islets by directly modulating α-cell cAMP. Biorxiv : the Preprint Server For Biology. PMID 37577685 DOI: 10.1101/2023.07.31.551113 |
0.338 |
|
2023 |
Schaid MD, Harrington JM, Kelly GM, Sdao SM, Merrins MJ, Kimple ME. EP3 signaling is decoupled from the regulation of glucose-stimulated insulin secretion in β-cells compensating for obesity and insulin resistance. Islets. 15: 2223327. PMID 37415404 DOI: 10.1080/19382014.2023.2223327 |
0.42 |
|
2023 |
Xu W, Qadir MMF, Nasteska D, Mota de Sa P, Gorvin CM, Blandino-Rosano M, Evans CR, Ho T, Potapenko E, Veluthakal R, Ashford FB, Bitsi S, Fan J, Bhondeley M, Song K, ... ... Merrins MJ, et al. Architecture of androgen receptor pathways amplifying glucagon-like peptide-1 insulinotropic action in male pancreatic β cells. Cell Reports. 42: 112529. PMID 37200193 DOI: 10.1016/j.celrep.2023.112529 |
0.305 |
|
2022 |
Foster HR, Ho T, Potapenko E, Sdao SM, Huang SM, Lewandowski SL, VanDeusen HR, Davidson SM, Cardone RL, Prentki M, Kibbey RG, Merrins MJ. β-cell deletion of the PKm1 and PKm2 isoforms of pyruvate kinase in mice reveal their essential role as nutrient sensors for the K channel. Elife. 11. PMID 35997256 DOI: 10.7554/eLife.79422 |
0.305 |
|
2022 |
Merrins MJ, Corkey BE, Kibbey RG, Prentki M. Metabolic cycles and signals for insulin secretion. Cell Metabolism. PMID 35728586 DOI: 10.1016/j.cmet.2022.06.003 |
0.354 |
|
2022 |
Emfinger CH, de Klerk E, Schueler KL, Rabaglia ME, Stapleton DS, Simonett SP, Mitok KA, Wang Z, Liu X, Paulo JA, Yu Q, Cardone RL, Foster HR, Lewandowski SL, Perales JC, ... ... Merrins MJ, et al. β Cell-specific deletion of Zfp148 improves nutrient-stimulated β cell Ca2+ responses. Jci Insight. 7. PMID 35603790 DOI: 10.1172/jci.insight.154198 |
0.434 |
|
2021 |
Corkey BE, Deeney JT, Merrins MJ. What Regulates Basal Insulin Secretion and Causes Hyperinsulinemia? Diabetes. 70: 2174-2182. PMID 34593535 DOI: 10.2337/dbi21-0009 |
0.341 |
|
2021 |
Lin H, Smith N, Spigelman AF, Suzuki K, Ferdaoussi M, Alghamdi TA, Lewandowski SL, Jin Y, Bautista A, Wang YW, Manning Fox JE, Merrins MJ, Buteau J, MacDonald PE. β-Cell Knockout of SENP1 Reduces Responses to Incretins and Worsens Oral Glucose Tolerance in High Fat Diet-Fed Mice. Diabetes. PMID 34462260 DOI: 10.2337/db20-1235 |
0.338 |
|
2021 |
Adams MT, Dwulet JM, Briggs JK, Reissaus CA, Jin E, Szulczewski JM, Lyman MR, Sdao SM, Kravets V, Nimkulrat SD, Ponik SM, Merrins MJ, Mirmira RG, Linnemann AK, Benninger RK, et al. Reduced synchroneity of intra-islet Ca oscillations in -deficient β cells. Elife. 10. PMID 34231467 DOI: 10.7554/eLife.61308 |
0.403 |
|
2021 |
El K, Gray SM, Capozzi ME, Knuth ER, Jin E, Svendsen B, Clifford A, Brown JL, Encisco SE, Chazotte BM, Sloop KW, Nunez DJ, Merrins MJ, D'Alessio DA, Campbell JE. GIP mediates the incretin effect and glucose tolerance by dual actions on α cells and β cells. Science Advances. 7. PMID 33712466 DOI: 10.1126/sciadv.abf1948 |
0.337 |
|
2021 |
Sdao SM, Ho T, Poudel C, Foster HR, De Leon ER, Adams MT, Lee JH, Blum B, Rane SG, Merrins MJ. CDK2 limits the highly energetic secretory program of mature β cells by restricting PEP cycle-dependent K channel closure. Cell Reports. 34: 108690. PMID 33503433 DOI: 10.1016/j.celrep.2021.108690 |
0.377 |
|
2020 |
Abulizi A, Cardone RL, Stark R, Lewandowski SL, Zhao X, Hillion J, Ma L, Sehgal R, Alves TC, Thomas C, Kung C, Wang B, Siebel S, Andrews ZB, Mason GF, ... ... Merrins MJ, et al. Multi-Tissue Acceleration of the Mitochondrial Phosphoenolpyruvate Cycle Improves Whole-Body Metabolic Health. Cell Metabolism. 32: 751-766.e11. PMID 33147485 DOI: 10.1016/j.cmet.2020.10.006 |
0.35 |
|
2020 |
Lewandowski SL, Cardone RL, Foster HR, Ho T, Potapenko E, Poudel C, VanDeusen HR, Sdao SM, Alves TC, Zhao X, Capozzi ME, de Souza AH, Jahan I, Thomas CJ, Nunemaker CS, ... ... Merrins MJ, et al. Pyruvate Kinase Controls Signal Strength in the Insulin Secretory Pathway. Cell Metabolism. 32: 736-750.e5. PMID 33147484 DOI: 10.1016/j.cmet.2020.10.007 |
0.404 |
|
2020 |
de Souza AH, Tang J, Yadev AK, Saghafi ST, Kibbe CR, Linnemann AK, Merrins MJ, Davis DB. Intra-islet GLP-1, but not CCK, is necessary for β-cell function in mouse and human islets. Scientific Reports. 10: 2823. PMID 32071395 DOI: 10.1038/S41598-020-59799-2 |
0.329 |
|
2019 |
Douros JD, Niu J, Sdao SM, Gregg T, Fisher-Wellman KH, Bharadwaj MS, Molina A, Arumugam R, Martin MD, Petretto E, Merrins MJ, Herman MA, Tong J, Campbell JE, D'Alessio D. Sleeve gastrectomy rapidly enhances islet function independently of body weight. Jci Insight. PMID 30777938 DOI: 10.1172/Jci.Insight.126688 |
0.304 |
|
2019 |
Capozzi ME, Svendsen B, Encisco SE, Lewandowski SL, Martin MD, Lin H, Jaffe JL, Coch RW, Haldeman JM, MacDonald PE, Merrins MJ, D'Alessio DA, Campbell JE. β-Cell tone is defined by proglucagon peptides through cyclic AMP signaling. Jci Insight. PMID 30720465 DOI: 10.1172/jci.insight.126742 |
0.362 |
|
2019 |
Gregg T, Sdao SM, Dhillon RS, Rensvold JW, Lewandowski SL, Pagliarini DJ, Denu JM, Merrins MJ. Obesity-dependent CDK1 signaling stimulates mitochondrial respiration at complex I in pancreatic β-cells. The Journal of Biological Chemistry. PMID 30700550 DOI: 10.1074/Jbc.Ra118.006085 |
0.355 |
|
2018 |
Hennings TG, Chopra DG, DeLeon ER, VanDeusen HR, Sesaki H, Merrins MJ, Ku GM. In vivo Deletion of Beta Cell Drp1 Impairs Insulin Secretion without Affecting Islet Oxygen Consumption. Endocrinology. PMID 30052866 DOI: 10.1210/En.2018-00445 |
0.395 |
|
2017 |
Hernandez R, Graves SA, Gregg T, VanDeusen HR, Fenske RJ, Wienkes HN, England CG, Valdovinos HF, Jeffery JJ, Barnhart TE, Severin GW, Nickles RJ, Kimple ME, Merrins MJ, Cai W. Radiomanganese PET Detects Changes in Functional β-cell Mass in Mouse Models of Diabetes. Diabetes. PMID 28515126 DOI: 10.2337/Db16-1285 |
0.323 |
|
2017 |
Neuman JC, Schaid MD, Brill AL, Fenske RJ, Kibbe CR, Fontaine DA, Sdao SM, Brar HK, Connors KM, Wienkes HN, Eliceiri KW, Merrins MJ, Davis DB, Kimple ME. Enriching Islet Phospholipids with Eicosapentaenoic Acid Reduces Prostaglandin E2 Signaling and Enhances Diabetic β-cell Function. Diabetes. PMID 28193789 DOI: 10.2337/Db16-1362 |
0.324 |
|
2017 |
Kim SY, Lee JH, Merrins MJ, Gavrilova O, Bisteau X, Kaldis P, Satin LS, Rane SG. Loss of Cyclin Dependent Kinase 2 in the Pancreas Links Primary β-cell Dysfunction to Progressive Depletion of β-cell Mass and Diabetes. The Journal of Biological Chemistry. PMID 28100774 DOI: 10.1074/jbc.M116.754077 |
0.564 |
|
2016 |
Gregg T, Poudel C, Schmidt BA, Dhillon RS, Sdao SM, Truchan NA, Baar EL, Fernandez LA, Denu JM, Eliceiri KW, Rogers JD, Kimple ME, Lamming DW, Merrins MJ. Pancreatic β cells from Mice Offset Age-Associated Mitochondrial Deficiency with Reduced KATP Channel Activity. Diabetes. PMID 27284112 DOI: 10.2337/Db16-0432 |
0.392 |
|
2016 |
Wynn ML, Yates JA, Evans CR, Van Wassenhove L, Wu ZF, Bridges S, Bao L, Fournier C, Ashrafzadeh S, Merrins MJ, Satin LS, Schnell S, Burant CF, Merajver SD. RhoC is a Potent Regulator of Glutamine Metabolism and N-acetylaspartate Production in Inflammatory Breast Cancer Cells. The Journal of Biological Chemistry. PMID 27129239 DOI: 10.1074/Jbc.M115.703959 |
0.506 |
|
2016 |
McKenna JP, Ha J, Merrins MJ, Satin LS, Sherman A, Bertram R. Ca(2+) Effects on ATP Production and Consumption Have Regulatory Roles on Oscillatory Islet Activity. Biophysical Journal. 110: 733-742. PMID 26840737 DOI: 10.1016/J.Bpj.2015.11.3526 |
0.663 |
|
2016 |
Merrins MJ, Poudel C, McKenna JP, Ha J, Sherman A, Bertram R, Satin LS. Phase Analysis of Metabolic Oscillations and Membrane Potential in Pancreatic Islet β-Cells. Biophysical Journal. 110: 691-699. PMID 26840733 DOI: 10.1016/J.Bpj.2015.12.029 |
0.655 |
|
2016 |
Lamming D, Cummings N, Arriola Apelo S, Neuman J, Schmidt B, Merrins M, Kimple M, Fontana L. ID: 78: IMPROVING GLYCEMIC CONTROL THROUGH REDUCTION OF SPECIFIC DIETARY AMINO ACIDS Journal of Investigative Medicine. 64: 926.1-926. DOI: 10.1136/Jim-2016-000120.32 |
0.336 |
|
2016 |
Poudel C, Schmidt BA, Harenda QE, Engin F, Eliceiri KW, Merrins MJ. TUDCA Rescues γ-Cell Metabolic Oscillations from ER Stress, Revealed By NAD(P)H-FLIM and FRET Biophysical Journal. 110: 142a-143a. DOI: 10.1016/J.Bpj.2015.11.810 |
0.391 |
|
2014 |
Watts M, Fendler B, Merrins MJ, Satin LS, Bertram R, Sherman A. Calcium and Metabolic Oscillations in Pancreatic Islets: Who's Driving the Bus?(*) Siam Journal On Applied Dynamical Systems. 13: 683-703. PMID 25698909 DOI: 10.1137/130920198 |
0.66 |
|
2014 |
Johnson JS, Kono T, Tong X, Yamamoto WR, Zarain-Herzberg A, Merrins MJ, Satin LS, Gilon P, Evans-Molina C. Pancreatic and duodenal homeobox protein 1 (Pdx-1) maintains endoplasmic reticulum calcium levels through transcriptional regulation of sarco-endoplasmic reticulum calcium ATPase 2b (SERCA2b) in the islet β cell. The Journal of Biological Chemistry. 289: 32798-810. PMID 25271154 DOI: 10.1074/Jbc.M114.575191 |
0.574 |
|
2014 |
Alejandro EU, Gregg B, Wallen T, Kumusoglu D, Meister D, Chen A, Merrins MJ, Satin LS, Liu M, Arvan P, Bernal-Mizrachi E. Maternal diet-induced microRNAs and mTOR underlie β cell dysfunction in offspring. The Journal of Clinical Investigation. 124: 4395-410. PMID 25180600 DOI: 10.1172/JCI74237 |
0.581 |
|
2014 |
Merrins MJ, Satin LS. Ca2+ has a Permissive Effect on Glycolytic Oscillations in Pancreatic Beta Cells Biophysical Journal. 106: 526a. DOI: 10.1016/j.bpj.2013.11.2937 |
0.63 |
|
2013 |
Merrins MJ, Van Dyke AR, Mapp AK, Rizzo MA, Satin LS. Direct measurements of oscillatory glycolysis in pancreatic islet β-cells using novel fluorescence resonance energy transfer (FRET) biosensors for pyruvate kinase M2 activity. The Journal of Biological Chemistry. 288: 33312-22. PMID 24100037 DOI: 10.1074/Jbc.M113.508127 |
0.611 |
|
2013 |
Merrins MJ, Kim SY, Rane SG, Satin LS. Cyclin Dependent Kinase 2 (CDK2) Regulates Secretory Function in Pancreatic Beta-Cells Biophysical Journal. 104: 621a. DOI: 10.1016/j.bpj.2012.11.3435 |
0.543 |
|
2012 |
Merrins MJ, Bertram R, Sherman A, Satin LS. Phosphofructo-2-kinase/fructose-2,6-bisphosphatase modulates oscillations of pancreatic islet metabolism. Plos One. 7: e34036. PMID 22532827 DOI: 10.1371/Journal.Pone.0034036 |
0.67 |
|
2012 |
Merrins MJ, Satin LS. A Novel FRET Biosensor For Measuring Glycolytic Activity: A Study of Pancreatic Beta-Cells Biophysical Journal. 102: 199a. DOI: 10.1016/j.bpj.2011.11.1084 |
0.556 |
|
2011 |
Merrins M, Bertram R, Sherman A, Satin L. Testing a Computational Model of Pancreatic Beta-Cell Oscillations Using Live-Cell Imaging of Islet Oscillatory Behavior Microscopy and Microanalysis. 17: 208-209. DOI: 10.1017/S1431927611001917 |
0.599 |
|
2011 |
Merrins MJ, Bertram R, Sherman A, Satin LS. 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase (PFKFB) Modulates Slow Oscillations in Pancreatic Islets Biophysical Journal. 100: 380a-381a. DOI: 10.1016/J.Bpj.2010.12.2265 |
0.655 |
|
2010 |
Merrins MJ, Fendler B, Zhang M, Sherman A, Bertram R, Satin LS. Metabolic oscillations in pancreatic islets depend on the intracellular Ca2+ level but not Ca2+ oscillations. Biophysical Journal. 99: 76-84. PMID 20655835 DOI: 10.1016/J.Bpj.2010.04.012 |
0.638 |
|
2009 |
Nunemaker CS, Dishinger JF, Dula SB, Wu R, Merrins MJ, Reid KR, Sherman A, Kennedy RT, Satin LS. Glucose metabolism, islet architecture, and genetic homogeneity in imprinting of [Ca2+](i) and insulin rhythms in mouse islets. Plos One. 4: e8428. PMID 20037650 DOI: 10.1371/Journal.Pone.0008428 |
0.648 |
|
2008 |
Merrins MJ, Stuenkel EL. Kinetics of Rab27a-dependent actions on vesicle docking and priming in pancreatic beta-cells. The Journal of Physiology. 586: 5367-81. PMID 18801842 DOI: 10.1113/Jphysiol.2008.158477 |
0.405 |
|
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