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Reka Agnes Haraszti, MD PhD - Publications

Affiliations: 
2018- Hematology/Oncology University of Tübingen, Germany 
Area:
siRNA, miRNA, exosomes, stem cells, GvHD
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22 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Haraszti RA, Braun JE. Comparative Colocalization Single-Molecule Spectroscopy (CoSMoS) with Multiple RNA Species. Methods in Molecular Biology (Clifton, N.J.). 2113: 23-29. PMID 32006305 DOI: 10.1007/978-1-0716-0278-2_3  0.373
2020 Haraszti RA, Braun JE. Preparation of SNAP-Beads for Colocalization Single-Molecule Spectroscopy (CoSMoS) of RNA-Protein Complexes. Methods in Molecular Biology (Clifton, N.J.). 2113: 17-22. PMID 32006304 DOI: 10.1007/978-1-0716-0278-2_2  0.365
2019 Alterman JF, Godinho BMDC, Hassler MR, Ferguson CM, Echeverria D, Sapp E, Haraszti RA, Coles AH, Conroy F, Miller R, Roux L, Yan P, Knox EG, Turanov AA, King RM, et al. A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system. Nature Biotechnology. 37: 884-894. PMID 31375812 DOI: 10.1038/S41587-019-0205-0  0.651
2019 Haraszti RA, Miller R, Dubuke ML, Rockwell HE, Coles AH, Sapp E, Didiot MC, Echeverria D, Stoppato M, Sere YY, Leszyk J, Alterman JF, Godinho BMDC, Hassler MR, McDaniel J, et al. Serum Deprivation of Mesenchymal Stem Cells Improves Exosome Activity and Alters Lipid and Protein Composition. Iscience. 16: 230-241. PMID 31195240 DOI: 10.1016/J.Isci.2019.05.029  0.64
2019 Biscans A, Coles A, Haraszti R, Echeverria D, Hassler M, Osborn M, Khvorova A. Diverse lipid conjugates for functional extra-hepatic siRNA delivery in vivo. Nucleic Acids Research. 47: 1082-1096. PMID 30544191 DOI: 10.1093/Nar/Gky1239  0.637
2018 Théry C, Witwer KW, Aikawa E, Alcaraz MJ, Anderson JD, Andriantsitohaina R, Antoniou A, Arab T, Archer F, Atkin-Smith GK, Ayre DC, Bach JM, Bachurski D, Baharvand H, Balaj L, ... ... Haraszti RA, et al. Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines. Journal of Extracellular Vesicles. 7: 1535750. PMID 30637094 DOI: 10.1080/20013078.2018.1535750  0.548
2018 Osborn MF, Coles AH, Biscans A, Haraszti RA, Roux L, Davis S, Ly S, Echeverria D, Hassler MR, Godinho BMDC, Nikan M, Khvorova A. Hydrophobicity drives the systemic distribution of lipid-conjugated siRNAs via lipid transport pathways. Nucleic Acids Research. PMID 30535404 DOI: 10.1093/Nar/Gky1232  0.63
2018 Turanov AA, Lo A, Hassler MR, Makris A, Ashar-Patel A, Alterman JF, Coles AH, Haraszti RA, Roux L, Godinho BMDC, Echeverria D, Pears S, Iliopoulos J, Shanmugalingam R, Ogle R, et al. RNAi modulation of placental sFLT1 for the treatment of preeclampsia. Nature Biotechnology. PMID 30451990 DOI: 10.1038/Nbt.4297  0.593
2018 Haraszti RA, Miller R, Stoppato M, Sere YY, Coles A, Didiot MC, Wollacott R, Sapp E, Dubuke M, Li X, Shaffer S, DiFiglia M, Wang Y, Aronin N, Khvorova A. Exosomes Produced from 3D Cultures of MSCs by Tangential Flow Filtration Show Higher Yield and Improved Activity. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 30341012 DOI: 10.1016/J.Ymthe.2018.09.015  0.556
2018 Godinho BMDC, Henninger N, Bouley J, Alterman JF, Haraszti RA, Gilbert JW, Sapp E, Coles AH, Biscans A, Nikan M, Echeverria D, DiFiglia M, Aronin N, Khvorova A. Transvascular Delivery of Hydrophobically Modified siRNAs: Gene Silencing in the Rat Brain upon Disruption of the Blood-Brain Barrier. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 30143435 DOI: 10.1016/J.Ymthe.2018.08.005  0.646
2018 Haraszti RA, Miller R, Didiot MC, Biscans A, Alterman JF, Hassler MR, Roux L, Echeverria D, Sapp E, DiFiglia M, Aronin N, Khvorova A. Optimized Cholesterol-siRNA Chemistry Improves Productive Loading onto Extracellular Vesicles. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 29937418 DOI: 10.1016/J.Ymthe.2018.05.024  0.654
2018 Sanchez-Ramos J, Song S, Kong X, Foroutan P, Martinez G, Dominguez-Viqueria W, Mohapatra S, Mohapatra S, Haraszti RA, Khvorova A, Aronin N, Sava V. Chitosan-Mangafodipir nanoparticles designed for intranasal delivery of siRNA and DNA to brain. Journal of Drug Delivery Science and Technology. 43: 453-460. PMID 29805475 DOI: 10.1016/J.Jddst.2017.11.013  0.626
2018 Biscans A, Haraszti RA, Echeverria D, Miller R, Didiot MC, Nikan M, Roux L, Aronin N, Khvorova A. Hydrophobicity of Lipid-Conjugated siRNAs Predicts Productive Loading to Small Extracellular Vesicles. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 29699940 DOI: 10.1016/J.Ymthe.2018.03.019  0.669
2018 Hassler MR, Turanov AA, Alterman JF, Haraszti RA, Coles AH, Osborn MF, Echeverria D, Nikan M, Salomon WE, Roux L, Godinho BMDC, Davis SM, Morrissey DV, Zamore PD, Karumanchi SA, et al. Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo. Nucleic Acids Research. PMID 29432571 DOI: 10.1093/Nar/Gky037  0.662
2018 Didiot MC, Haraszti RA, Aronin N, Khvorova A. Loading of Extracellular Vesicles with Hydrophobically Modified siRNAs. Methods in Molecular Biology (Clifton, N.J.). 1740: 199-214. PMID 29388146 DOI: 10.1007/978-1-4939-7652-2_16  0.656
2017 Godinho BMDC, Gilbert JW, Haraszti RA, Coles AH, Biscans A, Roux L, Nikan M, Echeverria D, Hassler M, Khvorova A. Pharmacokinetic Profiling of Conjugated Therapeutic Oligonucleotides: A High-Throughput Method Based Upon Serial Blood Microsampling Coupled to Peptide Nucleic Acid Hybridization Assay. Nucleic Acid Therapeutics. PMID 29022758 DOI: 10.1089/Nat.2017.0690  0.634
2017 Sharma VK, Singh SK, Krishnamurthy PM, Alterman JF, Haraszti RA, Khvorova A, Prasad AK, Watts JK. Synthesis and biological properties of triazole-linked locked nucleic acid. Chemical Communications (Cambridge, England). PMID 28736781 DOI: 10.1039/C7Cc04092J  0.562
2017 Haraszti RA, Roux L, Coles AH, Turanov AA, Alterman JF, Echeverria D, Godinho BMDC, Aronin N, Khvorova A. 5΄-Vinylphosphonate improves tissue accumulation and efficacy of conjugated siRNAs in vivo. Nucleic Acids Research. PMID 28591791 DOI: 10.1093/Nar/Gkx507  0.645
2017 Nikan M, Osborn MF, Coles AH, Biscans A, Godinho B, Haraszti R, Sapp E, Echeverria D, DiFiglia M, Aronin N, Khvorova A. Synthesis and Evaluation of Parenchymal Retention and Efficacy of a Metabolically Stable, O-phosphocholine-N-docosahexaenoyl-L-serine siRNA Conjugate in Mouse Brain. Bioconjugate Chemistry. PMID 28462988 DOI: 10.1021/Acs.Bioconjchem.7B00226  0.747
2016 Haraszti RA, Didiot MC, Sapp E, Leszyk J, Shaffer SA, Rockwell HE, Gao F, Narain NR, DiFiglia M, Kiebish MA, Aronin N, Khvorova A. High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources. Journal of Extracellular Vesicles. 5: 32570. PMID 27863537 DOI: 10.3402/Jev.V5.32570  0.573
2016 Didiot MC, Hall LM, Coles AH, Haraszti RA, Godinho BM, Chase K, Sapp E, Ly S, Alterman JF, Hassler MR, Echeverria D, Raj L, Morrissey DV, DiFiglia M, Aronin N, et al. Exosome-mediated Delivery of Hydrophobically Modified siRNA for Huntingtin mRNA Silencing. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 27506293 DOI: 10.1038/Mt.2016.126  0.754
2016 Nikan M, Osborn MF, Coles AH, Godinho BM, Hall LM, Haraszti RA, Hassler MR, Echeverria D, Aronin N, Khvorova A. Docosahexaenoic Acid Conjugation Enhances Distribution and Safety of siRNA upon Local Administration in Mouse Brain. Molecular Therapy. Nucleic Acids. 5: e344. PMID 27504598 DOI: 10.1038/Mtna.2016.50  0.746
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