Year |
Citation |
Score |
2019 |
Binukumar BK, Skuntz S, Prochazkova M, Kesavapany S, Amin ND, Shukla V, Grant P, Kulkarni AB, Pant HC. Overexpression of the Cdk5 inhibitory peptide in motor neurons rescue of amyotrophic lateral sclerosis phenotype in a mouse model. Human Molecular Genetics. PMID 31189016 DOI: 10.1093/Hmg/Ddz118 |
0.304 |
|
2017 |
Shukla V, Seo J, Binukumar BK, Amin ND, Reddy P, Grant P, Kuntz S, Kesavapany S, Steiner J, Mishra SK, Tsai LH, Pant HC. TFP5, a Peptide Inhibitor of Aberrant and Hyperactive Cdk5/p25, Attenuates Pathological Phenotypes and Restores Synaptic Function in CK-p25Tg Mice. Journal of Alzheimer's Disease : Jad. 56: 335-349. PMID 28085018 DOI: 10.3233/Jad-160916 |
0.398 |
|
2016 |
Amin ND, Zheng Y, Bk B, Shukla V, Skuntz S, Grant P, Steiner J, Bhaskar M, Pant HC. The interaction of Munc 18 (p67) with the p10 domain of p35 protects in vivo Cdk5/p35 activity from inhibition by TFP5, a peptide derived from p35. Molecular Biology of the Cell. PMID 27630261 DOI: 10.1091/Mbc.E15-12-0857 |
0.383 |
|
2016 |
Binukumar BK, Pelech SL, Sutter C, Shukla V, Amin ND, Grant P, Bhaskar M, Skuntz S, Steiner J, Pant HC. Profiling of p5, a 24 Amino Acid Inhibitory Peptide Derived from the CDK5 Activator, p35 CDKR1 Against 70 Protein Kinases. Journal of Alzheimer's Disease : Jad. PMID 27567857 DOI: 10.3233/Jad-160458 |
0.399 |
|
2016 |
Zheng YL, Zhang X, Fu HX, Guo M, Shukla V, Amin ND, E J, Bao L, Luo HY, Li B, Lu XH, Gao YC. Knockdown of Expression of Cdk5 or p35 (a Cdk5 Activator) Results in Podocyte Apoptosis. Plos One. 11: e0160252. PMID 27479491 DOI: 10.1371/Journal.Pone.0160252 |
0.36 |
|
2015 |
Binukumar BK, Shukla V, Amin ND, Bhaskar M, Skuntz S, Steiner J, Winkler D, Pelech SL, Pant HC. Analysis of the Inhibitory Elements in the p5 Peptide Fragment of the CDK5 Activator, p35, CDKR1 Protein. Journal of Alzheimer's Disease : Jad. PMID 26444778 DOI: 10.3233/Jad-150412 |
0.381 |
|
2015 |
Bk B, Shukla V, Amin ND, Grant P, M B, Kuntz S, Steiner J, Pant HC. Peptide (TFP5/TP5), derived from Cdk5 activator P35, provides neuroprotection in the MPTP model of Parkinson's disease. Molecular Biology of the Cell. PMID 26399293 DOI: 10.1091/Mbc.E15-06-0415 |
0.321 |
|
2014 |
Binukumar BK, Zheng YL, Shukla V, Amin ND, Grant P, Pant HC. TFP5, a peptide derived from p35, a Cdk5 neuronal activator, rescues cortical neurons from glucose toxicity. Journal of Alzheimer's Disease : Jad. 39: 899-909. PMID 24326517 DOI: 10.3233/Jad-131784 |
0.376 |
|
2013 |
Zheng YL, Li C, Hu YF, Cao L, Wang H, Li B, Lu XH, Bao L, Luo HY, Shukla V, Amin ND, Pant HC. Cdk5 inhibitory peptide (CIP) inhibits Cdk5/p25 activity induced by high glucose in pancreatic beta cells and recovers insulin secretion from p25 damage. Plos One. 8: e63332. PMID 24039692 DOI: 10.1371/Journal.Pone.0063332 |
0.333 |
|
2013 |
Binukumar BK, Shukla V, Amin ND, Reddy P, Skuntz S, Grant P, Pant HC. Topographic regulation of neuronal intermediate filaments by phosphorylation, role of peptidyl-prolyl isomerase 1: significance in neurodegeneration. Histochemistry and Cell Biology. 140: 23-32. PMID 23793952 DOI: 10.1007/S00418-013-1108-7 |
0.314 |
|
2013 |
Shukla V, Zheng YL, Mishra SK, Amin ND, Steiner J, Grant P, Kesavapany S, Pant HC. A truncated peptide from p35, a Cdk5 activator, prevents Alzheimer's disease phenotypes in model mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 174-86. PMID 23038754 DOI: 10.1096/Fj.12-217497 |
0.346 |
|
2012 |
Shukla V, Skuntz S, Pant HC. Deregulated Cdk5 activity is involved in inducing Alzheimer's disease. Archives of Medical Research. 43: 655-62. PMID 23142263 DOI: 10.1016/J.Arcmed.2012.10.015 |
0.375 |
|
2011 |
Shukla V, Pant HC. Hyperphosphorylation of tau by deregulated Cdk5 (Cdk5/p25) activity is inhibited by its truncated activator (p35) Neuroscience Research. 71: e186. DOI: 10.1016/J.Neures.2011.07.804 |
0.358 |
|
2010 |
Zheng YL, Li BS, Rudrabhatla P, Shukla V, Amin ND, Maric D, Kesavapany S, Kanungo J, Pareek TK, Takahashi S, Grant P, Kulkarni AB, Pant HC. Phosphorylation of p27Kip1 at Thr187 by cyclin-dependent kinase 5 modulates neural stem cell differentiation. Molecular Biology of the Cell. 21: 3601-14. PMID 20810788 DOI: 10.1091/Mbc.E10-01-0054 |
0.356 |
|
2010 |
Zheng YL, Amin ND, Hu YF, Rudrabhatla P, Shukla V, Kanungo J, Kesavapany S, Grant P, Albers W, Pant HC. A 24-residue peptide (p5), derived from p35, the Cdk5 neuronal activator, specifically inhibits Cdk5-p25 hyperactivity and tau hyperphosphorylation. The Journal of Biological Chemistry. 285: 34202-12. PMID 20720012 DOI: 10.1074/Jbc.M110.134643 |
0.403 |
|
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