Stephen G. Brohawn, PhD - Publications

Affiliations: 
Rockefeller University, New York, NY, United States 
 Molecular and Cell Biology University of California, Berkeley, Berkeley, CA 
Area:
Molecular basis of sensory transduction and cellular electrical signaling

30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Rietmeijer RA, Sorum B, Li B, Brohawn SG. Physical basis for distinct basal and mechanically gated activity of the human K channel TRAAK. Neuron. PMID 34390650 DOI: 10.1016/j.neuron.2021.07.009  1
2021 Kern DM, Sorum B, Mali SS, Hoel CM, Sridharan S, Remis JP, Toso DB, Kotecha A, Bautista DM, Brohawn SG. Author Correction: Cryo-EM structure of SARS-CoV-2 ORF3a in lipid nanodiscs. Nature Structural & Molecular Biology. PMID 34285420 DOI: 10.1038/s41594-021-00642-1  1
2021 Kern DM, Sorum B, Mali SS, Hoel CM, Sridharan S, Remis JP, Toso DB, Kotecha A, Bautista DM, Brohawn SG. Cryo-EM structure of SARS-CoV-2 ORF3a in lipid nanodiscs. Nature Structural & Molecular Biology. PMID 34158638 DOI: 10.1038/s41594-021-00619-0  1
2021 Kern DM, Brohawn SG. SARS-CoV-2 3a expression, purification, and reconstitution into lipid nanodiscs. Methods in Enzymology. 653: 207-235. PMID 34099172 DOI: 10.1016/bs.mie.2020.12.020  1
2021 Wang JY, Hoel CM, Al-Shayeb B, Banfield JF, Brohawn SG, Doudna JA. Structural coordination between active sites of a CRISPR reverse transcriptase-integrase complex. Nature Communications. 12: 2571. PMID 33958590 DOI: 10.1038/s41467-021-22900-y  1
2021 Sorum B, Rietmeijer RA, Gopakumar K, Adesnik H, Brohawn SG. Ultrasound activates mechanosensitive TRAAK K channels through the lipid membrane. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33542098 DOI: 10.1073/pnas.2006980118  1
2020 Li B, Rietmeijer RA, Brohawn SG. Structural basis for pH gating of the two-pore domain K channel TASK2. Nature. 586: 457-462. PMID 32999458 DOI: 10.1038/s41586-020-2770-2  1
2020 Kern DM, Sorum B, Hoel CM, Sridharan S, Remis JP, Toso DB, Brohawn SG. Cryo-EM structure of the SARS-CoV-2 3a ion channel in lipid nanodiscs. Biorxiv : the Preprint Server For Biology. PMID 32587976 DOI: 10.1101/2020.06.17.156554  1
2020 Reid MS, Kern DM, Brohawn SG. Cryo-EM structure of the potassium-chloride cotransporter KCC4 in lipid nanodiscs. Elife. 9. PMID 32286222 DOI: 10.7554/Elife.52505  1
2019 Brohawn SG, Wang W, Handler A, Campbell EB, Schwarz JR, MacKinnon R. The mechanosensitive ion channel TRAAK is localized to the mammalian node of Ranvier. Elife. 8. PMID 31674909 DOI: 10.7554/Elife.50403  1
2019 Kern DM, Oh S, Hite RK, Brohawn SG. Cryo-EM structures of the DCPIB-inhibited volume-regulated anion channel LRRC8A in lipid nanodiscs. Elife. 8. PMID 30775971 DOI: 10.7554/Elife.42636  1
2019 Reid MS, Kern DM, Brohawn SG. Author response: Cryo-EM structure of the potassium-chloride cotransporter KCC4 in lipid nanodiscs Elife. DOI: 10.7554/Elife.52505.Sa2  1
2019 Brohawn SG, Wang W, Handler A, Campbell EB, Schwarz JR, MacKinnon R. Author response: The mechanosensitive ion channel TRAAK is localized to the mammalian node of Ranvier Elife. DOI: 10.7554/Elife.50403.022  1
2019 Kern DM, Oh S, Hite RK, Brohawn SG. Author response: Cryo-EM structures of the DCPIB-inhibited volume-regulated anion channel LRRC8A in lipid nanodiscs Elife. DOI: 10.7554/Elife.42636.048  1
2018 Mardinly AR, Oldenburg IA, Pégard NC, Sridharan S, Lyall EH, Chesnov K, Brohawn SG, Waller L, Adesnik H. Precise multimodal optical control of neural ensemble activity. Nature Neuroscience. PMID 29713079 DOI: 10.1038/S41593-018-0139-8  1
2018 Del Mármol J, Rietmeijer RA, Brohawn SG. Studying Mechanosensitivity of Two-Pore Domain K(+) Channels in Cellular and Reconstituted Proteoliposome Membranes. Methods in Molecular Biology (Clifton, N.J.). 1684: 129-150. PMID 29058189 DOI: 10.1007/978-1-4939-7362-0_11  1
2015 Brohawn SG. How ion channels sense mechanical force: insights from mechanosensitive K2P channels TRAAK, TREK1, and TREK2. Annals of the New York Academy of Sciences. 1352: 20-32. PMID 26332952 DOI: 10.1111/Nyas.12874  1
2014 Brohawn SG, Campbell EB, MacKinnon R. Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel. Nature. 516: 126-30. PMID 25471887 DOI: 10.1038/Nature14013  1
2014 Brohawn SG, Su Z, MacKinnon R. Mechanosensitivity is mediated directly by the lipid membrane in TRAAK and TREK1 K+ channels. Proceedings of the National Academy of Sciences of the United States of America. 111: 3614-9. PMID 24550493 DOI: 10.1073/Pnas.1320768111  1
2013 Brohawn SG, Campbell EB, MacKinnon R. Domain-swapped chain connectivity and gated membrane access in a Fab-mediated crystal of the human TRAAK K+ channel. Proceedings of the National Academy of Sciences of the United States of America. 110: 2129-34. PMID 23341632 DOI: 10.1073/Pnas.1218950110  1
2012 Brohawn SG, del Mármol J, MacKinnon R. Crystal structure of the human K2P TRAAK, a lipid- and mechano-sensitive K+ ion channel. Science (New York, N.Y.). 335: 436-41. PMID 22282805 DOI: 10.1126/Science.1213808  1
2009 Brohawn SG, Schwartz TU. Molecular architecture of the Nup84-Nup145C-Sec13 edge element in the nuclear pore complex lattice. Nature Structural & Molecular Biology. 16: 1173-7. PMID 19855394 DOI: 10.1038/Nsmb.1713  1
2009 Brohawn SG, Partridge JR, Whittle JR, Schwartz TU. The nuclear pore complex has entered the atomic age. Structure (London, England : 1993). 17: 1156-68. PMID 19748337 DOI: 10.1016/J.Str.2009.07.014  1
2009 Brohawn SG, Schwartz TU. A lattice model of the nuclear pore complex. Communicative & Integrative Biology. 2: 205-7. PMID 19641729 DOI: 10.4161/Cib.2.3.7873  1
2009 Leksa NC, Brohawn SG, Schwartz TU. The structure of the scaffold nucleoporin Nup120 reveals a new and unexpected domain architecture. Structure (London, England : 1993). 17: 1082-91. PMID 19576787 DOI: 10.1016/J.Str.2009.06.003  1
2009 Rich RL, Papalia GA, Flynn PJ, Furneisen J, Quinn J, Klein JS, Katsamba PS, Waddell MB, Scott M, Thompson J, Berlier J, Corry S, Baltzinger M, Zeder-Lutz G, Schoenemann A, ... ... Brohawn S, et al. A global benchmark study using affinity-based biosensors. Analytical Biochemistry. 386: 194-216. PMID 19133223 DOI: 10.1016/J.Ab.2008.11.021  1
2008 Brohawn SG, Leksa NC, Spear ED, Rajashankar KR, Schwartz TU. Structural evidence for common ancestry of the nuclear pore complex and vesicle coats. Science (New York, N.Y.). 322: 1369-73. PMID 18974315 DOI: 10.1126/Science.1165886  1
2006 Schwartz TU, Schmidt D, Brohawn SG, Blobel G. Homodimerization of the G protein SRbeta in the nucleotide-free state involves proline cis/trans isomerization in the switch II region. Proceedings of the National Academy of Sciences of the United States of America. 103: 6823-8. PMID 16627619 DOI: 10.1073/Pnas.0602083103  1
2004 Cline DJ, Redding SE, Brohawn SG, Psathas JN, Schneider JP, Thorpe C. New water-soluble phosphines as reductants of peptide and protein disulfide bonds: reactivity and membrane permeability. Biochemistry. 43: 15195-203. PMID 15568811 DOI: 10.1021/Bi048329A  1
2003 Brohawn SG, Miksa IR, Thorpe C. Avian sulfhydryl oxidase is not a metalloenzyme: adventitious binding of divalent metal ions to the enzyme. Biochemistry. 42: 11074-82. PMID 12974644 DOI: 10.1021/Bi0301385  1
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