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Alex J Guseman - Publications

Affiliations: 
University of Pittsburgh Medical School, PA 15232 USA 
Area:
Structural Biology
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20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Zhao H, Wu H, Guseman A, Abeykoon D, Camara CM, Dalal Y, Fushman D, Papoian GA. The role of cryptic ancestral symmetry in histone folding mechanisms across Eukarya and Archaea. Plos Computational Biology. 20: e1011721. PMID 38181064 DOI: 10.1371/journal.pcbi.1011721  0.301
2023 Heath SL, Guseman AJ, Gronenborn AM, Horne WS. Probing Effects of Site-Specific Aspartic Acid Isomerization on Structure and Stability of GB1 through Chemical Protein Synthesis. Protein Science : a Publication of the Protein Society. e4883. PMID 38143426 DOI: 10.1002/pro.4883  0.554
2023 Guseman AJ, Rennick LJ, Nambulli S, Roy CN, Martinez DR, Yang DT, Bhinderwala F, Vergara S, Schaefer A, Baric RS, Ambrose Z, Duprex WP, Gronenborn AM. Targeting spike glycans to inhibit SARS-CoV2 viral entry. Proceedings of the National Academy of Sciences of the United States of America. 120: e2301518120. PMID 37695910 DOI: 10.1073/pnas.2301518120  0.302
2022 Guseman AJ, Rennick LJ, Nambulli S, Roy CN, Martinez DR, Yang DT, Bhinderwhala F, Vergara S, Baric RS, Ambrose Z, Duprex WP, Gronenborn AM. Targeting Spike Glycans to Inhibit SARS-CoV2 Viral Entry. Biorxiv : the Preprint Server For Biology. PMID 36597530 DOI: 10.1101/2022.12.22.521642  0.307
2022 Zhu W, Guseman AJ, Bhinderwala F, Lu M, Su XC, Gronenborn AM. Visualizing Proteins in Mammalian Cells by F NMR Spectroscopy. Angewandte Chemie (International Ed. in English). e202201097. PMID 35278268 DOI: 10.1002/anie.202201097  0.527
2021 Speer SL, Zheng W, Jiang X, Chu IT, Guseman AJ, Liu M, Pielak GJ, Li C. The intracellular environment affects protein-protein interactions. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33836588 DOI: 10.1073/pnas.2019918118  0.795
2020 Krone MW, Albanese KI, Leighton GO, He CQ, Lee GY, Garcia-Borràs M, Guseman AJ, Williams DC, Houk KN, Brustad EM, Waters ML. Thermodynamic consequences of Tyr to Trp mutations in the cation-π-mediated binding of trimethyllysine by the HP1 chromodomain. Chemical Science. 11: 3495-3500. PMID 34109021 DOI: 10.1039/d0sc00227e  0.337
2020 Guseman AJ, Whitley MJ, González JJ, Rathi N, Ambarian M, Gronenborn AM. Assessing the Structures and Interactions of γD-Crystallin Deamidation Variants. Structure (London, England : 1993). PMID 33264606 DOI: 10.1016/j.str.2020.11.006  0.329
2020 Krone MW, Albanese KI, Leighton GO, He CQ, Lee GY, Garcia-Borràs M, Guseman AJ, Williams DC, Houk KN, Brustad EM, Waters ML. Thermodynamic consequences of Tyr to Trp mutations in the cation–π-mediated binding of trimethyllysine by the HP1 chromodomain Chemical Science. 11: 3495-3500. DOI: 10.1039/D0Sc00227E  0.418
2020 Guseman AJ, Whitley MJ, Gonzalez J, Gronenborn AM. Deamidation of yD-Crystallin - Effects on Structure and Interaction Properties Biophysical Journal. 118: 336a. DOI: 10.1016/J.Bpj.2019.11.1875  0.364
2019 Guseman AJ, Gronenborn AM. Isomerization as the secret Achilles' heel of long-lived proteins. The Journal of Biological Chemistry. 294: 7556-7557. PMID 31076522 DOI: 10.1074/Jbc.H119.008716  0.45
2019 Speer SL, Guseman AJ, Patteson JB, Ehrmann BM, Pielak GJ. Controlling and quantifying protein concentration in Escherichia coli. Protein Science : a Publication of the Protein Society. PMID 31054180 DOI: 10.1002/Pro.3637  0.716
2019 Piszkiewicz S, Gunn KH, Warmuth O, Propst A, Mehta A, Nguyen KH, Kuhlman E, Guseman AJ, Stadmiller SS, Boothby TC, Neher SB, Pielak GJ. Protecting activity of desiccated enzymes. Protein Science : a Publication of the Protein Society. PMID 30868674 DOI: 10.1002/Pro.3604  0.673
2019 Speer SL, Guseman AJ, Pielak GJ. Quantifying a Protein-Protein Interaction in Living Cells Biophysical Journal. 116: 61a. DOI: 10.1016/J.Bpj.2018.11.375  0.782
2018 Guseman AJ, Perez Goncalves GM, Speer SL, Young GB, Pielak GJ. Protein shape modulates crowding effects. Proceedings of the National Academy of Sciences of the United States of America. PMID 30301792 DOI: 10.1073/Pnas.1810054115  0.761
2018 Guseman AJ, Speer SL, Perez Goncalves GM, Pielak GJ. Surface-charge modulates protein-protein interactions in physiologically-relevant environments. Biochemistry. PMID 29473738 DOI: 10.1021/Acs.Biochem.8B00061  0.753
2017 Stadmiller SS, Gorensek-Benitez AH, Guseman AJ, Pielak GJ. Osmotic-shock induced protein destabilization in living cells and its reversal by glycine betaine. Journal of Molecular Biology. PMID 28263768 DOI: 10.1016/J.Jmb.2017.03.001  0.529
2017 Guseman AJ, Pielak GJ. Cosolute and Crowding Effects on a Side-By-Side Protein Dimer. Biochemistry. PMID 28102665 DOI: 10.1021/Acs.Biochem.6B01251  0.793
2016 Guseman AJ, Lanier ST, Pielak GJ. Crowding and Protein Dimerization Biophysical Journal. 110: 213a. DOI: 10.1016/J.Bpj.2015.11.1184  0.752
2015 Cohen RD, Guseman AJ, Pielak GJ. Intracellular pH modulates quinary structure. Protein Science : a Publication of the Protein Society. PMID 26257390 DOI: 10.1002/Pro.2765  0.715
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