| Year |
Citation |
Score |
| 2023 |
Krahn N, Zhang J, Melnikov SV, Tharp JM, Villa A, Patel A, Howard RJ, Gabir H, Patel TR, Stetefeld J, Puglisi J, Söll D. tRNA shape is an identity element for an archaeal pyrrolysyl-tRNA synthetase from the human gut. Nucleic Acids Research. PMID 38100361 DOI: 10.1093/nar/gkad1188 |
0.514 |
|
| 2023 |
Jiang HK, Tharp JM. Reprogramming Initiator and Nonsense Codons to Simultaneously Install Three Distinct Noncanonical Amino Acids into Proteins in E. coli. Methods in Molecular Biology (Clifton, N.J.). 2676: 101-116. PMID 37277627 DOI: 10.1007/978-1-0716-3251-2_7 |
0.76 |
|
| 2023 |
Jiang HK, Ambrose NL, Chung CZ, Wang YS, Söll D, Tharp JM. Split aminoacyl-tRNA synthetases for proximity-induced stop codon suppression. Proceedings of the National Academy of Sciences of the United States of America. 120: e2219758120. PMID 36787361 DOI: 10.1073/pnas.2219758120 |
0.679 |
|
| 2022 |
Hampton JT, Lalonde TJ, Tharp JM, Kurra Y, Alugubelli YR, Roundy CM, Hamer GL, Xu S, Liu WR. Novel Regioselective Approach to Cyclize Phage-Displayed Peptides in Combination with Epitope-Directed Selection to Identify a Potent Neutralizing Macrocyclic Peptide for SARS-CoV-2. Acs Chemical Biology. PMID 36174018 DOI: 10.1021/acschembio.2c00565 |
0.719 |
|
| 2022 |
Guo LT, Amikura K, Jiang HK, Mukai T, Fu X, Wang YS, O'Donoghue P, Söll D, Tharp JM. Ancestral Archaea Expanded the Genetic Code with Pyrrolysine. The Journal of Biological Chemistry. 102521. PMID 36152750 DOI: 10.1016/j.jbc.2022.102521 |
0.709 |
|
| 2022 |
Fischer JT, Söll D, Tharp JM. Directed Evolution of Pyrrolysyl-tRNA Synthetase Generates a Hyperactive and Highly Selective Variant. Frontiers in Molecular Biosciences. 9: 850613. PMID 35372501 DOI: 10.3389/fmolb.2022.850613 |
0.512 |
|
| 2021 |
Tharp JM, Walker JA, Söll D, Schepartz A. Initiating protein synthesis with noncanonical monomers in vitro and in vivo. Methods in Enzymology. 656: 495-519. PMID 34325796 DOI: 10.1016/bs.mie.2021.05.002 |
0.584 |
|
| 2021 |
Tharp JM, Vargas-Rodriguez O, Schepartz A, Söll D. Genetic Encoding of Three Distinct Noncanonical Amino Acids Using Reprogrammed Initiator and Nonsense Codons. Acs Chemical Biology. PMID 33723984 DOI: 10.1021/acschembio.1c00120 |
0.772 |
|
| 2020 |
Krahn N, Tharp JM, Crnković A, Söll D. Engineering aminoacyl-tRNA synthetases for use in synthetic biology. The Enzymes. 48: 351-395. PMID 33837709 DOI: 10.1016/bs.enz.2020.06.004 |
0.593 |
|
| 2020 |
Tharp JM, Hampton JT, Reed CA, Ehnbom A, Chen PC, Morse JS, Kurra Y, Pérez LM, Xu S, Liu WR. An amber obligate active site-directed ligand evolution technique for phage display. Nature Communications. 11: 1392. PMID 32170178 DOI: 10.1038/S41467-020-15057-7 |
0.545 |
|
| 2020 |
Tharp JM, Krahn N, Varshney U, Söll D. Hijacking Translation Initiation for Synthetic Biology. Chembiochem : a European Journal of Chemical Biology. PMID 32023356 DOI: 10.1002/Cbic.202000017 |
0.595 |
|
| 2020 |
Tharp JM, Krahn N, Varshney U, Söll D. Front Cover: Hijacking Translation Initiation for Synthetic Biology (ChemBioChem 10/2020) Chembiochem. 21: 1383-1383. DOI: 10.1002/Cbic.202000239 |
0.46 |
|
| 2019 |
Tharp JM, Ad O, Amikura K, Ward FR, Garcia EM, Cate JHD, Schepartz A, Söll D. Initiation of Protein Synthesis with Non-canonical Amino Acids In Vivo. Angewandte Chemie (International Ed. in English). PMID 31828898 DOI: 10.1002/Anie.201914671 |
0.584 |
|
| 2019 |
Liu W, Wang X, Chen PH, Hampton JT, Tharp J, Reed C, Das S, Wang DS, Hayatshahi H, Shen Y, Liu J. A Genetically Encoded, Phage-Displayed Cyclic Peptide Library. Angewandte Chemie (International Ed. in English). PMID 31398275 DOI: 10.1002/Anie.201908713 |
0.516 |
|
| 2018 |
Tharp JM, Liu WR. Using Amber and Ochre Nonsense Codons to Code Two Different Noncanonical Amino Acids in One Protein Gene. Methods in Molecular Biology (Clifton, N.J.). 1728: 147-154. PMID 29404996 DOI: 10.1007/978-1-4939-7574-7_9 |
0.616 |
|
| 2017 |
Tharp JM, Liu WR. Genetic code expansion: Synthetases pick up the PACE. Nature Chemical Biology. 13: 1205-1206. PMID 29161249 DOI: 10.1038/Nchembio.2516 |
0.535 |
|
| 2017 |
Tharp JM, Ehnbom A, Liu WR. tRNA(pyl): Structure, function, and applications. Rna Biology. 0. PMID 28837402 DOI: 10.1080/15476286.2017.1356561 |
0.624 |
|
| 2016 |
Wang ZA, Zeng Y, Kurra Y, Wang X, Tharp JM, Vatansever EC, Hsu WW, Dai S, Fang X, Liu WR. A Genetically Encoded Allysine for the Synthesis of Proteins with Site-Specific Lysine Dimethylation. Angewandte Chemie (International Ed. in English). PMID 27910233 DOI: 10.1002/Anie.201609452 |
0.641 |
|
| 2016 |
Lee YJ, Schmidt MJ, Tharp JM, Weber A, Koenig AL, Zheng H, Gao J, Waters ML, Summerer D, Liu WR. Genetically encoded fluorophenylalanines enable insights into the recognition of lysine trimethylation by an epigenetic reader. Chemical Communications (Cambridge, England). PMID 27711380 DOI: 10.1039/C6Cc05959G |
0.717 |
|
| 2016 |
Tharp JM, Liu W. The "pi-Clamp" Offers a Novel Strategy for Site-selective Protein Modification. Chembiochem : a European Journal of Chemical Biology. PMID 26928847 DOI: 10.1002/Cbic.201600106 |
0.548 |
|
| 2015 |
Piscotta FJ, Tharp JM, Liu WR, Link AJ. Expanding the chemical diversity of lasso peptide MccJ25 with genetically encoded noncanonical amino acids. Chemical Communications (Cambridge, England). 51: 409-12. PMID 25407838 DOI: 10.1039/C4Cc07778D |
0.584 |
|
| 2014 |
Wan W, Tharp JM, Liu WR. Pyrrolysyl-tRNA synthetase: an ordinary enzyme but an outstanding genetic code expansion tool. Biochimica Et Biophysica Acta. 1844: 1059-70. PMID 24631543 DOI: 10.1016/J.Bbapap.2014.03.002 |
0.632 |
|
| 2014 |
Tharp JM, Wang YS, Lee YJ, Yang Y, Liu WR. Genetic incorporation of seven ortho-substituted phenylalanine derivatives. Acs Chemical Biology. 9: 884-90. PMID 24451054 DOI: 10.1021/Cb400917A |
0.724 |
|
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