| Year |
Citation |
Score |
| 2024 |
Hariharan P, Shi Y, Katsube S, Willibal K, Burrows ND, Mitchell P, Bakhtiiari A, Stanfield S, Pardon E, Kaback HR, Liang R, Steyaert J, Viner R, Guan L. Mobile barrier mechanisms for Na-coupled symport in an MFS sugar transporter. Elife. 12. PMID 38381130 DOI: 10.7554/eLife.92462 |
0.553 |
|
| 2024 |
Yoon S, Bae HE, Hariharan P, Nygaard A, Lan B, Woubshete M, Sadaf A, Liu X, Loland CJ, Byrne B, Guan L, Chae PS. Rational Approach to Improve Detergent Efficacy for Membrane Protein Stabilization. Bioconjugate Chemistry. PMID 38215010 DOI: 10.1021/acs.bioconjchem.3c00507 |
0.353 |
|
| 2023 |
Ghani L, Kim S, Ehsan M, Lan B, Poulsen IH, Dev C, Katsube S, Byrne B, Guan L, Loland CJ, Liu X, Im W, Chae PS. Melamine-cored glucosides for membrane protein solubilization and stabilization: importance of water-mediated intermolecular hydrogen bonding in detergent performance. Chemical Science. 14: 13014-13024. PMID 38023530 DOI: 10.1039/d3sc03543c |
0.354 |
|
| 2023 |
Hariharan P, Shi Y, Katsube S, Willibal K, Burrows ND, Mitchell P, Bakhtiiari A, Stanfield S, Pardon E, Kaback HR, Liang R, Steyaert J, Viner R, Guan L. Mimicking the regulatory state of a major facilitator superfamily sugar transporter. Biorxiv : the Preprint Server For Biology. PMID 37790566 DOI: 10.1101/2023.09.18.558283 |
0.553 |
|
| 2023 |
Blaimschein N, Parameswaran H, Nagler G, Manioglu S, Helenius J, Ardelean C, Kuhn A, Guan L, Müller DJ. The insertase YidC chaperones the polytopic membrane protein MelB inserting and folding simultaneously from both termini. Structure (London, England : 1993). 31: 1419-1430.e5. PMID 37708891 DOI: 10.1016/j.str.2023.08.012 |
0.387 |
|
| 2023 |
Katsube S, Willibal K, Vemulapally S, Hariharan P, Tikhonova E, Pardon E, Kaback HR, Steyaert J, Guan L. In vivo and in vitro characterizations of melibiose permease (MelB) conformation- dependent nanobodies reveal sugar-binding mechanisms. The Journal of Biological Chemistry. 104967. PMID 37380079 DOI: 10.1016/j.jbc.2023.104967 |
0.554 |
|
| 2023 |
Ghani L, Zhang X, Munk CF, Hariharan P, Lan B, Yun HS, Byrne B, Guan L, Loland CJ, Liu X, Chae PS. Tris(hydroxymethyl)aminomethane Linker-Bearing Triazine-Based Triglucosides for Solubilization and Stabilization of Membrane Proteins. Bioconjugate Chemistry. PMID 36919927 DOI: 10.1021/acs.bioconjchem.3c00042 |
0.367 |
|
| 2023 |
Chua GL, Tan BC, Loke RYJ, He M, Chin CF, Wong BH, Kuk ACY, Ding M, Wenk MR, Guan L, Torta F, Silver DL. Mfsd2a utilizes a flippase mechanism to mediate omega-3 fatty acid lysolipid transport. Proceedings of the National Academy of Sciences of the United States of America. 120: e2215290120. PMID 36848557 DOI: 10.1073/pnas.2215290120 |
0.347 |
|
| 2022 |
Lee HS, Das M, Mahler F, Ahmed W, Wang H, Mortensen JS, Hariharan P, Ghani L, Byrne B, Guan L, Loland CJ, Keller S, Chae PS. 3,4-Bis(hydroxymethyl)hexane-1,6-diol-based maltosides (HDMs) for membrane-protein study: Importance of detergent rigidity-flexibility balance in protein stability. Chemistry, An Asian Journal. PMID 36253323 DOI: 10.1002/asia.202200941 |
0.36 |
|
| 2022 |
Guan L. Structure and mechanism of membrane transporters. Scientific Reports. 12: 13248. PMID 35918457 DOI: 10.1038/s41598-022-17524-1 |
0.337 |
|
| 2022 |
Lee HJ, Ehsan M, Zhang X, Katsube S, Munk CF, Wang H, Ahmed W, Kumar A, Byrne B, Loland CJ, Guan L, Liu X, Chae PS. Development of 1,3-acetonedicarboxylate-derived glucoside amphiphiles (ACAs) for membrane protein study. Chemical Science. 13: 5750-5759. PMID 35694361 DOI: 10.1039/d2sc00539e |
0.358 |
|
| 2022 |
Katsube S, Liang R, Amin A, Hariharan P, Guan L. Molecular basis for the cation selectivity of Salmonella typhimurium melibiose permease. Journal of Molecular Biology. 167598. PMID 35461877 DOI: 10.1016/j.jmb.2022.167598 |
0.38 |
|
| 2022 |
Ghani L, Kim S, Wang H, Lee HS, Mortensen JS, Katsube S, Du Y, Sadaf A, Byrne B, Guan L, Loland CJ, Kobilka BK, Im W, Chae PS, Ahmed W. Foldable detergents for membrane protein study: Importance of detergent core flexibility in protein stabilization. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 35238091 DOI: 10.1002/chem.202200116 |
0.363 |
|
| 2022 |
Ehsan M, Wang H, Katsube S, Munk CF, Du Y, Youn T, Yoon S, Byrne B, Loland CJ, Guan L, Kobilka BK, Chae PS. Glyco-steroidal amphiphiles (GSAs) for membrane protein structural study. Chembiochem : a European Journal of Chemical Biology. PMID 35129249 DOI: 10.1002/cbic.202200027 |
0.356 |
|
| 2021 |
Ehsan M, Wang H, Cecchetti C, Mortensen JS, Du Y, Hariharan P, Nygaard A, Lee HJ, Ghani L, Guan L, Loland CJ, Byrne B, Kobilka BK, Chae PS. Maltose-bis(hydroxymethyl)phenol (MBPs) and Maltose-tris(hydroxymethyl)phenol (MTPs) Amphiphiles for Membrane Protein Stability. Acs Chemical Biology. PMID 34445864 DOI: 10.1021/acschembio.1c00578 |
0.372 |
|
| 2021 |
Markham KJ, Tikhonova EB, Scarpa AC, Hariharan P, Katsube S, Guan L. Complete cysteine-scanning mutagenesis of the Salmonella typhimurium melibiose permease. The Journal of Biological Chemistry. 101090. PMID 34416232 DOI: 10.1016/j.jbc.2021.101090 |
0.42 |
|
| 2021 |
Guan L, Hariharan P. X-ray crystallography reveals molecular recognition mechanism for sugar binding in a melibiose transporter MelB. Communications Biology. 4: 931. PMID 34341464 DOI: 10.1038/s42003-021-02462-x |
0.366 |
|
| 2021 |
Hariharan P, Guan L. Cooperative binding ensures the obligatory melibiose/Na+ cotransport in MelB. The Journal of General Physiology. 153. PMID 34110360 DOI: 10.1085/jgp.202012710 |
0.338 |
|
| 2021 |
Sadaf A, Kim S, Bae HE, Wang H, Nygaard A, Uegaki Y, Du Y, Munk CF, Katsube S, Bae J, Choi CW, Choi HJ, Byrne B, Gellman SH, Guan L, et al. Conformationally flexible core-bearing detergents with a hydrophobic or hydrophilic pendant: Effect of pendant polarity on detergent conformation and membrane protein stability. Acta Biomaterialia. PMID 33933694 DOI: 10.1016/j.actbio.2021.04.043 |
0.327 |
|
| 2020 |
Das M, Mahler F, Hariharan P, Wang H, Du Y, Mortensen JS, Patallo EP, Ghani L, Glück D, Lee HJ, Byrne B, Loland CJ, Guan L, Kobilka BK, Keller S, et al. Diastereomeric Cyclopentane-Based Maltosides (CPMs) as Tools for Membrane Protein Study. Journal of the American Chemical Society. PMID 33315387 DOI: 10.1021/jacs.0c09629 |
0.372 |
|
| 2020 |
Bae HE, Cecchetti C, Du Y, Katsube S, Mortensen JS, Huang W, Rehan S, Lee HJ, Loland CJ, Guan L, Kobilka BK, Byrne B, Chae PS. Pendant-bearing glucose-neopentyl glycol (P-GNG) amphiphiles for membrane protein manipulation: Importance of detergent pendant chain for protein stabilization. Acta Biomaterialia. PMID 32522715 DOI: 10.1016/J.Actbio.2020.06.001 |
0.468 |
|
| 2020 |
Ehsan M, Katsube S, Cecchetti C, Du Y, Mortensen JS, Wang H, Nygaard A, Ghani L, Loland CJ, Kobilka BK, Byrne B, Guan L, Chae PS. New Malonate-Derived Tetraglucoside Detergents for Membrane Protein Stability. Acs Chemical Biology. PMID 32501004 DOI: 10.1021/Acschembio.0C00316 |
0.463 |
|
| 2020 |
Parameswaran H, Guan L. Cooperative Substrate Binding Converges to the Closed Conformations in the Sodium-Coupled Melibiose Symporter MelB Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.2471 |
0.379 |
|
| 2019 |
Ghani L, Munk CF, Zhang X, Katsube S, Du Y, Cecchetti C, Huang W, Bae HE, Saouros S, Ehsan M, Guan L, Liu X, Loland CJ, Kobilka BK, Byrne B, et al. 1,3,5-Triazine-Cored Maltoside Amphiphiles for Membrane Protein Extraction and Stabilization. Journal of the American Chemical Society. PMID 31809039 DOI: 10.1021/Jacs.9B07883 |
0.476 |
|
| 2019 |
Sadaf A, Ramos M, Mortensen JS, Du Y, Bae HE, Munk CF, Hariharan P, Byrne B, Kobilka BK, Loland CJ, Guan L, Chae PS. Conformationally restricted monosaccharide-cored glycoside amphiphiles: the effect of detergent head group variation on membrane protein stability. Acs Chemical Biology. PMID 31305987 DOI: 10.1021/Acschembio.9B00166 |
0.457 |
|
| 2019 |
Chae PS, Ehsan M, Du Y, Mortensen JS, Hariharan P, Qu Q, Ghani L, Das M, Grethen A, Byrne B, Skiniotis G, Keller S, Loland CJ, Guan L, Kobilka BK. Self-assembly behaviors and application of terphenyl-cored trimaltosides for membrane protein study: Impact of detergent hydrophobic group geometry on protein stability. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31243822 DOI: 10.1002/Chem.201902468 |
0.458 |
|
| 2019 |
Kaback HR, Guan L. It takes two to tango: The dance of the permease. The Journal of General Physiology. PMID 31147449 DOI: 10.1085/Jgp.201912377 |
0.653 |
|
| 2019 |
Ehsan M, Kumar A, Mortensen JS, Du Y, Hariharan P, Kumar KK, Ha B, Byrne B, Guan L, Kobilka BK, Loland CJ, Chae PS. Self-Assembly Behaviors of a Penta-Phenylene Maltoside and Its Application for Membrane Protein Study. Chemistry, An Asian Journal. PMID 30969484 DOI: 10.1002/Asia.201900224 |
0.409 |
|
| 2019 |
Das M, Du Y, Mortensen JS, Ramos M, Ghani L, Lee HJ, Bae HE, Byrne B, Guan L, Loland CJ, Kobilka BK, Chae PS. Trehalose-cored amphiphiles for membrane protein stabilization: importance of the detergent micelle size in GPCR stability. Organic & Biomolecular Chemistry. PMID 30843907 DOI: 10.1039/C8Ob03153C |
0.476 |
|
| 2019 |
Bae HE, Du Y, Hariharan P, Mortensen JS, Kumar KK, Ha B, Das M, Lee HS, Loland CJ, Guan L, Kobilka BK, Chae PS. Asymmetric maltose neopentyl glycol amphiphiles for a membrane protein study: effect of detergent asymmetricity on protein stability. Chemical Science. 10: 1107-1116. PMID 30774908 DOI: 10.1039/C8Sc02560F |
0.442 |
|
| 2018 |
Hussain H, Helton T, Du Y, Mortensen JS, Hariharan P, Ehsan M, Byrne B, Loland CJ, Kobilka BK, Guan L, Chae PS. A comparative study of branched and linear mannitol-based amphiphiles on membrane protein stability. The Analyst. PMID 30334564 DOI: 10.1039/C8An01408F |
0.359 |
|
| 2018 |
Hariharan P, Tikhonova E, Medeiros-Silva J, Jeucken A, Bogdanov MV, Dowhan W, Brouwers JF, Weingarth M, Guan L. Structural and functional characterization of protein-lipid interactions of the Salmonella typhimurium melibiose transporter MelB. Bmc Biology. 16: 85. PMID 30075778 DOI: 10.1186/S12915-018-0553-0 |
0.489 |
|
| 2018 |
Chae PS, Das M, Du Y, Mortensen JS, Hariharan P, Byrne B, Loland CJ, Guan L, Kobilka B, Lee HS. Rationally engineered tandem facial amphiphiles for improved membrane protein stabilization efficacy. Chembiochem : a European Journal of Chemical Biology. PMID 30070754 DOI: 10.1002/Cbic.201800388 |
0.452 |
|
| 2018 |
Chae PS, Ehsan M, Das M, Stern V, Du Y, Mortensen J, Hariharan P, Byrne B, Loland C, Kobilka B, Guan L. Steroid-based amphiphiles for membrane protein study: Importance of alkyl spacer for protein stability. Chembiochem : a European Journal of Chemical Biology. PMID 29660780 DOI: 10.1002/Cbic.201800106 |
0.351 |
|
| 2018 |
Ehsan M, Du Y, Molist I, Seven AB, Hariharan P, Mortensen JS, Ghani L, Loland CJ, Skiniotis G, Guan L, Byrne B, Kobilka BK, Chae PS. Vitamin E-based glycoside amphiphiles for membrane protein structural studies. Organic & Biomolecular Chemistry. PMID 29564464 DOI: 10.1039/C8Ob00270C |
0.359 |
|
| 2017 |
Sadaf A, Du Y, Santillan C, Mortensen JS, Molist I, Seven AB, Hariharan P, Skiniotis G, Loland CJ, Kobilka BK, Guan L, Byrne B, Chae PS. Dendronic trimaltoside amphiphiles (DTMs) for membrane protein study. Chemical Science. 8: 8315-8324. PMID 29619178 DOI: 10.1039/C7Sc03700G |
0.468 |
|
| 2017 |
Hariharan P, Guan L. Thermodynamic cooperativity of cosubstrate binding and cation selectivity of Salmonella typhimurium MelB. The Journal of General Physiology. PMID 29054867 DOI: 10.1085/Jgp.201711788 |
0.447 |
|
| 2017 |
Ehsan M, Ghani L, Du Y, Hariharan P, Mortensen JS, Ribeiro O, Hu H, Skiniotis G, Loland CJ, Guan L, Kobilka BK, Byrne B, Chae PS. New penta-saccharide-bearing tripod amphiphiles for membrane protein structure studies. The Analyst. PMID 28913526 DOI: 10.1039/C7An01168G |
0.351 |
|
| 2017 |
Hussain H, Mortensen JS, Du Y, Santillan C, Ribeiro O, Go J, Hariharan P, Loland CJ, Guan L, Kobilka BK, Byrne B, Chae PS. Tandem malonate-based glucosides (TMGs) for membrane protein structural studies. Scientific Reports. 7: 3963. PMID 28638082 DOI: 10.1038/S41598-017-03809-3 |
0.448 |
|
| 2017 |
Das M, Du Y, Mortensen JS, Ribeiro O, Hariharan P, Guan L, Loland CJ, Kobilka BK, Byrne B, Chae PS. Butane-1,2,3,4-tetraol-based amphiphilic stereoisomers for membrane protein study: importance of chirality in the linker region. Chemical Science. 8: 1169-1177. PMID 28451257 DOI: 10.1039/C6Sc02981G |
0.438 |
|
| 2017 |
Chae PS, Hussain H, Du Y, Tikhonova E, Mortensen J, Ribeiro O, Santillan C, Das M, Løland C, Guan L, Kobilka B, Byrne B, Ehsan M. Resorcinarene-based facial glycosides: implication of detergent flexibility on membrane protein stability. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28303608 DOI: 10.1002/Chem.201605016 |
0.364 |
|
| 2017 |
Das M, Du Y, Ribeiro O, Hariharan P, Mortensen JS, Patra D, Skiniotis G, Loland CJ, Guan L, Kobilka BK, Byrne B, Chae PS. Conformationally Preorganized Diastereomeric Norbornane-Based Maltosides for Membrane Protein Study: Implications of Detergent Kink for Micellar Properties. Journal of the American Chemical Society. PMID 28218862 DOI: 10.1021/Jacs.6B11997 |
0.469 |
|
| 2017 |
Parameswaran H, Guan L. Insights into the Cation Selectivity and Cooperativity with Sugar in Salmonella Typhimurium Melibiose Permease Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.125 |
0.405 |
|
| 2016 |
Cho KH, Hariharan P, Mortensen JS, Du Y, Nielsen AK, Byrne B, Kobilka BK, Loland CJ, Guan L, Chae PS. Isomeric Detergent Comparison for Membrane Protein Stability: Importance of Inter-Alkyl-Chain Distance and Alkyl Chain Length. Chembiochem : a European Journal of Chemical Biology. 17: 2334-2339. PMID 27981750 DOI: 10.1002/Cbic.201600429 |
0.459 |
|
| 2016 |
Chae PS, Cho KH, Ribeiro O, Du Y, Tikhonova E, Mortensen J, Markham K, Hariharan P, Løland C, Guan L, Kobilka B, Byrne B. Mesitylene-cored glucoside amphiphiles (MGAs) for membrane protein studies: importance of alkyl chain density in detergent efficacy. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27743406 DOI: 10.1002/Chem.201603338 |
0.438 |
|
| 2016 |
Hariharan P, Andersson M, Jiang X, Pardon E, Steyaert J, Kaback HR, Guan L. Thermodynamics of nanobody binding to lactose permease. Biochemistry. PMID 27686537 DOI: 10.1021/Acs.Biochem.6B00826 |
0.583 |
|
| 2016 |
Sadaf A, Mortensen JS, Capaldi S, Tikhonova E, Hariharan P, de Castro Ribeiro O, Loland CJ, Guan L, Byrne B, Chae PS. A Class of Rigid Linker-bearing Glucosides for Membrane Protein Structural Study. Chemical Science (Royal Society of Chemistry : 2010). 7: 1933-1939. PMID 27110345 DOI: 10.1039/C5Sc02900G |
0.457 |
|
| 2016 |
Ehsan M, Du Y, Scull NJ, Tikhonova E, Tarrasch J, Mortensen JS, Loland CJ, Skiniotis G, Guan L, Byrne B, Kobilka BK, Chae PS. Highly Branched Pentasaccharide-Bearing Amphiphiles for Membrane Protein Studies. Journal of the American Chemical Society. PMID 26966956 DOI: 10.1021/Jacs.5B13233 |
0.462 |
|
| 2016 |
Sadaf A, Mortensen JS, Capaldi S, Tikhonova E, Hariharan P, Ribeiro O, Loland CJ, Guan L, Byrne B, Chae PS. A class of rigid linker-bearing glucosides for membrane protein structural study Chemical Science. 7: 1933-1939. DOI: 10.1039/c5sc02900g |
0.354 |
|
| 2016 |
Parameswaran H, Jiang X, Pardon E, Steyaert J, Kaback HR, Guan L. Thermodynamic Insights into Conformational Dynamics of Sugar Transporters Biophysical Journal. 110: 137a. DOI: 10.1016/J.Bpj.2015.11.784 |
0.634 |
|
| 2015 |
Amin A, Hariharan P, Chae PS, Guan L. Effect of Detergents on Galactoside Binding by Melibiose Permeases. Biochemistry. 54: 5849-55. PMID 26352464 DOI: 10.1021/Acs.Biochem.5B00660 |
0.467 |
|
| 2015 |
Cho KH, Du Y, Scull NJ, Hariharan P, Gotfryd K, Loland CJ, Guan L, Byrne B, Kobilka BK, Chae PS. Novel Xylene-Linked Maltoside Amphiphiles (XMAs) for Membrane Protein Stabilisation. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 10008-13. PMID 26013293 DOI: 10.1002/Chem.201501083 |
0.449 |
|
| 2015 |
Cho KH, Husri M, Amin A, Gotfryd K, Lee HJ, Go J, Kim JW, Loland CJ, Guan L, Byrne B, Chae PS. Maltose neopentyl glycol-3 (MNG-3) analogues for membrane protein study. The Analyst. 140: 3157-63. PMID 25813698 DOI: 10.1039/C5An00240K |
0.445 |
|
| 2015 |
Hariharan P, Balasubramaniam D, Peterkofsky A, Kaback HR, Guan L. Thermodynamic mechanism for inhibition of lactose permease by the phosphotransferase protein IIAGlc. Proceedings of the National Academy of Sciences of the United States of America. 112: 2407-12. PMID 25675534 DOI: 10.1073/Pnas.1500891112 |
0.595 |
|
| 2015 |
Tikhonova EB, Ethayathulla AS, Su Y, Hariharan P, Xie S, Guan L. A transcription blocker isolated from a designed repeat protein combinatorial library by in vivo functional screen. Scientific Reports. 5: 8070. PMID 25627011 DOI: 10.1038/Srep08070 |
0.381 |
|
| 2015 |
Parmeswaran H, Dhandayuthapani B, Peterkofsky A, Kaback RH, Guan L. Thermodynamic Features of IIAGlc Inhibition of Sugar Symporters Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.179 |
0.481 |
|
| 2014 |
Hariharan P, Guan L. Insights into the inhibitory mechanisms of the regulatory protein IIA(Glc) on melibiose permease activity. The Journal of Biological Chemistry. 289: 33012-9. PMID 25296751 DOI: 10.1074/Jbc.M114.609255 |
0.451 |
|
| 2014 |
Amin A, Ethayathulla AS, Guan L. Suppression of conformation-compromised mutants of Salmonella enterica serovar Typhimurium MelB. Journal of Bacteriology. 196: 3134-9. PMID 24957620 DOI: 10.1128/Jb.01868-14 |
0.368 |
|
| 2014 |
Ethayathulla AS, Yousef MS, Amin A, Leblanc G, Kaback HR, Guan L. Structure-based mechanism for Na(+)/melibiose symport by MelB. Nature Communications. 5: 3009. PMID 24389923 DOI: 10.1038/Ncomms4009 |
0.61 |
|
| 2014 |
Tikhonova EB, Parameswaran H, Su Y, Anowarul A, Guan L. Functional Inhibition of Sugar Transport by a Designed Novel Protein Biophysical Journal. 106: 3-7. DOI: 10.1016/J.Bpj.2013.11.2080 |
0.408 |
|
| 2014 |
Amin A, Ethayathulla AS, Guan L. Ionic Locks in Melibiose Permease: Scope towards GLUT1 Deficiency Syndrome Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.2079 |
0.42 |
|
| 2013 |
Chae PS, Kruse AC, Gotfryd K, Rana RR, Cho KH, Rasmussen SG, Bae HE, Chandra R, Gether U, Guan L, Kobilka BK, Loland CJ, Byrne B, Gellman SH. Novel tripod amphiphiles for membrane protein analysis. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 15645-51. PMID 24123610 DOI: 10.1002/Chem.201301423 |
0.448 |
|
| 2013 |
Chae PS, Rasmussen SGF, Rana RR, Gotfryd K, Kruse AC, Manglik A, Cho KH, Nurva S, Gether U, Guan L, Loland CJ, Byrne B, Kobilka BK, Gellman SH. Corrigendum: A New Class of Amphiphiles Bearing Rigid Hydrophobic Groups for Solubilization and Stabilization of Membrane Proteins Chemistry - a European Journal. 19: 4964-4964. DOI: 10.1002/Chem.201300856 |
0.407 |
|
| 2012 |
Jakkula SV, Guan L. Reduced Na+ affinity increases turnover of Salmonella enterica serovar Typhimurium MelB. Journal of Bacteriology. 194: 5538-44. PMID 22865849 DOI: 10.1128/Jb.01206-12 |
0.416 |
|
| 2012 |
Chae PS, Rasmussen SG, Rana RR, Gotfryd K, Kruse AC, Manglik A, Cho KH, Nurva S, Gether U, Guan L, Loland CJ, Byrne B, Kobilka BK, Gellman SH. A new class of amphiphiles bearing rigid hydrophobic groups for solubilization and stabilization of membrane proteins. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 9485-90. PMID 22730191 DOI: 10.1002/Chem.201200069 |
0.427 |
|
| 2012 |
Guan L, Jakkula SV, Hodkoff AA, Su Y. Role of Gly117 in the cation/melibiose symport of MelB of Salmonella typhimurium. Biochemistry. 51: 2950-7. PMID 22413840 DOI: 10.1021/Bi300230H |
0.464 |
|
| 2012 |
Jiang X, Guan L, Zhou Y, Hong WX, Zhang Q, Kaback HR. Evidence for an intermediate conformational state of LacY. Proceedings of the National Academy of Sciences of the United States of America. 109: E698-704. PMID 22355148 DOI: 10.1073/Pnas.1201107109 |
0.654 |
|
| 2012 |
Chae PS, Rasmussen SGF, Rana RR, Gotfryd K, Kruse AC, Manglik A, Cho KH, Nurva S, Gether U, Guan L, Loland CJ, Byrne B, Kobilka BK, Gellman SH. Inside Cover: A New Class of Amphiphiles Bearing Rigid Hydrophobic Groups for Solubilization and Stabilization of Membrane Proteins (Chem. Eur. J. 31/2012) Chemistry - a European Journal. 18: 9434-9434. DOI: 10.1002/Chem.201290131 |
0.404 |
|
| 2011 |
Zhou Y, Madej MG, Guan L, Nie Y, Kaback HR. An early event in the transport mechanism of LacY protein: interaction between helices V and I. The Journal of Biological Chemistry. 286: 30415-22. PMID 21730060 DOI: 10.1074/Jbc.M111.268433 |
0.757 |
|
| 2011 |
Chaptal V, Kwon S, Sawaya MR, Guan L, Kaback HR, Abramson J. Crystal structure of lactose permease in complex with an affinity inactivator yields unique insight into sugar recognition. Proceedings of the National Academy of Sciences of the United States of America. 108: 9361-6. PMID 21593407 DOI: 10.1073/pnas.1105687108 |
0.539 |
|
| 2011 |
Kudugunti SK, Thorsheim H, Yousef MS, Guan L, Moridani MY. The metabolic bioactivation of caffeic acid phenethyl ester (CAPE) mediated by tyrosinase selectively inhibits glutathione S-transferase. Chemico-Biological Interactions. 192: 243-56. PMID 21458432 DOI: 10.1016/J.Cbi.2011.03.015 |
0.301 |
|
| 2011 |
Guan L, Nurva S, Ankeshwarapu SP. Mechanism of melibiose/cation symport of the melibiose permease of Salmonella typhimurium. The Journal of Biological Chemistry. 286: 6367-74. PMID 21148559 DOI: 10.1074/Jbc.M110.206227 |
0.371 |
|
| 2010 |
Chae PS, Rasmussen SG, Rana RR, Gotfryd K, Chandra R, Goren MA, Kruse AC, Nurva S, Loland CJ, Pierre Y, Drew D, Popot JL, Picot D, Fox BG, Guan L, et al. Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins. Nature Methods. 7: 1003-8. PMID 21037590 DOI: 10.1038/Nmeth.1526 |
0.467 |
|
| 2010 |
Fiori MC, Guan L, Reuss L, Altenberg GA. Oligomeric State of Purified Wild-Type and Deafness-Associated Mutants Solubilized in Decylmaltoside Biophysical Journal. 98: 93a. DOI: 10.1016/J.Bpj.2009.12.523 |
0.353 |
|
| 2009 |
Guan L, Kaback HR. Properties of a LacY efflux mutant. Biochemistry. 48: 9250-5. PMID 19719233 DOI: 10.1021/Bi9014067 |
0.625 |
|
| 2009 |
Yousef MS, Guan L. A 3D structure model of the melibiose permease of Escherichia coli represents a distinctive fold for Na+ symporters. Proceedings of the National Academy of Sciences of the United States of America. 106: 15291-6. PMID 19706416 DOI: 10.1073/Pnas.0905516106 |
0.501 |
|
| 2008 |
Zhou Y, Guan L, Freites JA, Kaback HR. Opening and closing of the periplasmic gate in lactose permease. Proceedings of the National Academy of Sciences of the United States of America. 105: 3774-8. PMID 18319336 DOI: 10.1073/Pnas.0800825105 |
0.582 |
|
| 2007 |
Guan L, Mirza O, Verner G, Iwata S, Kaback HR. Structural determination of wild-type lactose permease. Proceedings of the National Academy of Sciences of the United States of America. 104: 15294-8. PMID 17881559 DOI: 10.1073/Pnas.0707688104 |
0.634 |
|
| 2007 |
Guan L, Kaback HR. Site-directed alkylation of cysteine to test solvent accessibility of membrane proteins. Nature Protocols. 2: 2012-7. PMID 17703213 DOI: 10.1038/Nprot.2007.275 |
0.607 |
|
| 2006 |
Guan L, Kaback HR. Lessons from lactose permease. Annual Review of Biophysics and Biomolecular Structure. 35: 67-91. PMID 16689628 DOI: 10.1146/Annurev.Biophys.35.040405.102005 |
0.624 |
|
| 2006 |
Mirza O, Guan L, Verner G, Iwata S, Kaback HR. Structural evidence for induced fit and a mechanism for sugar/H+ symport in LacY. The Embo Journal. 25: 1177-83. PMID 16525509 DOI: 10.1038/Sj.Emboj.7601028 |
0.581 |
|
| 2006 |
Guan L, Smirnova IN, Verner G, Nagamori S, Nagamoni S, Kaback HR. Manipulating phospholipids for crystallization of a membrane transport protein. Proceedings of the National Academy of Sciences of the United States of America. 103: 1723-6. PMID 16446422 DOI: 10.1073/Pnas.0510922103 |
0.692 |
|
| 2006 |
Guan L, Smirnova IN, Verner G, Nagamori S, Kaback HR. Correction for Guan et al., Manipulating phospholipids for crystallization of a membrane transport protein Proceedings of the National Academy of Sciences of the United States of America. 103: 6073-6073. DOI: 10.1073/Pnas.0601039103 |
0.574 |
|
| 2004 |
Vázquez-Ibar JL, Guan L, Weinglass AB, Verner G, Gordillo R, Kaback HR. Sugar recognition by the lactose permease of Escherichia coli. The Journal of Biological Chemistry. 279: 49214-21. PMID 15364943 DOI: 10.1074/jbc.M407408200 |
0.549 |
|
| 2004 |
Guan L, Kaback HR. Binding affinity of lactose permease is not altered by the H+ electrochemical gradient. Proceedings of the National Academy of Sciences of the United States of America. 101: 12148-52. PMID 15304639 DOI: 10.1073/Pnas.0404936101 |
0.616 |
|
| 2003 |
Vázquez-Ibar JL, Guan L, Svrakic M, Kaback HR. Exploiting luminescence spectroscopy to elucidate the interaction between sugar and a tryptophan residue in the lactose permease of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 100: 12706-11. PMID 14566061 DOI: 10.1073/Pnas.1835645100 |
0.559 |
|
| 2003 |
Ermolova N, Guan L, Kaback HR. Intermolecular thiol cross-linking via loops in the lactose permease of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 100: 10187-92. PMID 12934015 DOI: 10.1073/Pnas.1434239100 |
0.623 |
|
| 2003 |
Guan L, Hu Y, Kaback HR. Aromatic stacking in the sugar binding site of the lactose permease. Biochemistry. 42: 1377-82. PMID 12578349 DOI: 10.1021/Bi027152M |
0.607 |
|
| 2003 |
Guan L, Sahin-Tóth M, Kálai T, Hideg K, Kaback HR. Probing the mechanism of a membrane transport protein with affinity inactivators. The Journal of Biological Chemistry. 278: 10641-8. PMID 12471022 DOI: 10.1074/Jbc.M211355200 |
0.578 |
|
| 2002 |
Sorgen PL, Hu Y, Guan L, Kaback HR, Girvin ME. An approach to membrane protein structure without crystals. Proceedings of the National Academy of Sciences of the United States of America. 99: 14037-40. PMID 12391320 DOI: 10.1073/Pnas.182552199 |
0.616 |
|
| 2002 |
Guan L, Sahin-Toth M, Kaback HR. Changing the lactose permease of Escherichia coli into a galactose-specific symporter. Proceedings of the National Academy of Sciences of the United States of America. 99: 6613-8. PMID 12011425 DOI: 10.1073/Pnas.102178299 |
0.558 |
|
| 2002 |
Guan L, Murphy FD, Kaback HR. Surface-exposed positions in the transmembrane helices of the lactose permease of Escherichia coli determined by intermolecular thiol cross-linking. Proceedings of the National Academy of Sciences of the United States of America. 99: 3475-80. PMID 11904412 DOI: 10.1073/Pnas.052703699 |
0.569 |
|
| 2002 |
Zhang W, Guan L, Kaback HR. Helices VII and X in the lactose permease of Escherichia coli: proximity and ligand-induced distance changes. Journal of Molecular Biology. 315: 53-62. PMID 11771965 DOI: 10.1006/Jmbi.2001.5206 |
0.595 |
|
| 2001 |
Guan L, Weinglass AB, Kaback HR. Helix packing in the lactose permease of Escherichia coli: localization of helix VI. Journal of Molecular Biology. 312: 69-77. PMID 11545586 DOI: 10.1006/Jmbi.2001.4933 |
0.546 |
|
| 2001 |
Guan L, Nakae T. Identification of essential charged residues in transmembrane segments of the multidrug transporter MexB of Pseudomonas aeruginosa Journal of Bacteriology. 183: 1734-1739. PMID 11160105 DOI: 10.1128/Jb.183.5.1734-1739.2001 |
0.648 |
|
| 1999 |
Guan L, Ehrmann M, Yoneyama H, Nakae T. Membrane topology of the xenobiotic-exporting subunit, MexB, of the MexA,B-OprM extrusion pump in Pseudomonas aeruginosa. Journal of Biological Chemistry. 274: 10517-10522. PMID 10187844 DOI: 10.1074/Jbc.274.15.10517 |
0.684 |
|
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