Greta Vargova, Ph.D - Related publications

Department of Molecular, Cell and Systems Biology University of California, Riverside, Riverside, CA, United States 
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Chung DC, Roemer S, Petrucelli L, Dickson DW. Cellular and pathological heterogeneity of primary tauopathies. Molecular Neurodegeneration. 16: 57. PMID 34425874 DOI: 10.1186/s13024-021-00476-x   
2021 Durairajan SSK, Selvarasu K, Bera MR, Rajaram K, Iyaswamy A, Li M. Alzheimer's Disease and other Tauopathies: Exploring Efficacy of Medicinal Plant-Derived Compounds in Alleviating Tau-Mediated Neurodegeneration. Current Molecular Pharmacology. PMID 34488602 DOI: 10.2174/1874467214666210906125318   
2021 Dai B, Zhong T, Chen ZX, Chen W, Zhang N, Liu XL, Wang LQ, Chen J, Liang Y. Myricetin slows liquid-liquid phase separation of Tau and activates ATG5-dependent autophagy to suppress Tau toxicity. The Journal of Biological Chemistry. 101222. PMID 34560101 DOI: 10.1016/j.jbc.2021.101222   
2021 Nies SH, Takahashi H, Herber CS, Huttner A, Chase A, Strittmatter SM. Spreading of Alzheimer Tau seeds is enhanced by aging and template matching with limited impact of amyloid-β. The Journal of Biological Chemistry. 101159. PMID 34480901 DOI: 10.1016/j.jbc.2021.101159   
2021 Sharma A, Anand JS, Kumar Y. Immunotherapeutics for AD: A Work in Progress. Cns & Neurological Disorders Drug Targets. PMID 34477533 DOI: 10.2174/1871527320666210903101522   
2021 Utz J, Berner J, Muñoz LE, Oberstein TJ, Kornhuber J, Herrmann M, Maler JM, Spitzer P. Cerebrospinal Fluid of Patients With Alzheimer's Disease Contains Increased Percentages of Synaptophysin-Bearing Microvesicles. Frontiers in Aging Neuroscience. 13: 682115. PMID 34295239 DOI: 10.3389/fnagi.2021.682115   
2021 Britton RJ, Hutchison JM, Sanders CR. The transmembrane amyloid precursor C99 protein exhibits non-specific interaction with tau. Biochemical and Biophysical Research Communications. 576: 48-52. PMID 34481234 DOI: 10.1016/j.bbrc.2021.08.075   
2021 Wei X, Xie L, Du P, Zhao Z. Impacts of DNA methylation on Tau protein related genes in the brains of patients with Alzheimer's Disease. Neuroscience Letters. 136196. PMID 34437990 DOI: 10.1016/j.neulet.2021.136196   
2021 Colato E, Chiotis K, Ferreira D, Mazrina MS, Lemoine L, Mohanty R, Westman E, Nordberg A, Rodriguez-Vieitez E, . Assessment of Tau Pathology as Measured by 18F-THK5317 and 18F-Flortaucipir PET and Their Relation to Brain Atrophy and Cognition in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 34511502 DOI: 10.3233/JAD-210614   
2021 Phillips JS, Nitchie FJ, Da Re F, Olm CA, Cook PA, McMillan CT, Irwin DJ, Gee JC, Dubroff JG, Grossman M, Nasrallah IM, . Rates of longitudinal change in F-flortaucipir PET vary by brain region, cognitive impairment, and age in atypical Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 34515411 DOI: 10.1002/alz.12456   
2021 Xia Y, Bell BM, Giasson BI. Tau K321/K353 pseudoacetylation within KXGS motifs regulates tau-microtubule interactions and inhibits aggregation. Scientific Reports. 11: 17069. PMID 34426645 DOI: 10.1038/s41598-021-96627-7   
2021 Shang Y, Ding S. Flavonoids from Scutellaria baicalensis Georgi Stems and Leaves Regulate the Brain Tau Hyperphosphorylation at M|ultiple Sites Induced by Composited Aβ in Rats. Cns & Neurological Disorders Drug Targets. PMID 34455972 DOI: 10.2174/1871527320666210827112609   
2021 Russell JC, Lei H, Chaliparambil RK, Fish S, Markiewicz SM, Lee TI, Noori A, Kaeberlein M. Generation and characterization of a tractable C. elegans model of tauopathy. Geroscience. PMID 34536202 DOI: 10.1007/s11357-021-00436-9   
2021 Cheng C, Reis SA, Adams ET, Fass DM, Angus SP, Stuhlmiller TJ, Richardson J, Olafson H, Wang ET, Patnaik D, Beauchamp RL, Feldman DA, Silva MC, Sur M, Johnson GL, et al. High-content image-based analysis and proteomic profiling identifies Tau phosphorylation inhibitors in a human iPSC-derived glutamatergic neuronal model of tauopathy. Scientific Reports. 11: 17029. PMID 34426604 DOI: 10.1038/s41598-021-96227-5   
2021 Ledreux A, Thomas S, Hamlett ED, Trautman C, Gilmore A, Rickman Hager E, Paredes DA, Margittai M, Fortea J, Granholm AC. Small Neuron-Derived Extracellular Vesicles from Individuals with Down Syndrome Propagate Tau Pathology in the Wildtype Mouse Brain. Journal of Clinical Medicine. 10. PMID 34501378 DOI: 10.3390/jcm10173931   
2021 Lo CH. Recent advances in cellular biosensor technology to investigate tau oligomerization. Bioengineering & Translational Medicine. 6: e10231. PMID 34589603 DOI: 10.1002/btm2.10231   
2021 Govindaraju T, Ramesh M, Acharya A, Murugan NA, Ila H. Thiophene-Based Dual Modulators of Aβ and Tau Aggregation. Chembiochem : a European Journal of Chemical Biology. PMID 34546619 DOI: 10.1002/cbic.202100383   
2021 Xia L, Pang Y, Li J, Wu B, Du Y, Chen Y, Luo M, Wang Y, Dong Z. Dihydroartemisinin Induces O-GlcNAcylation and Improves Cognitive Function in a Mouse Model of Tauopathy. Journal of Alzheimer's Disease : Jad. PMID 34511503 DOI: 10.3233/JAD-210643   
2021 Wang M, Lv J, Huang X, Wisniewski T, Zhang W. High-fat diet-induced atherosclerosis promotes neurodegeneration in the triple transgenic (3 × Tg) mouse model of Alzheimer's disease associated with chronic platelet activation. Alzheimer's Research & Therapy. 13: 144. PMID 34454596 DOI: 10.1186/s13195-021-00890-9   
2021 Sharma C, Kim SR. Linking Oxidative Stress and Proteinopathy in Alzheimer's Disease. Antioxidants (Basel, Switzerland). 10. PMID 34439479 DOI: 10.3390/antiox10081231   
2021 Yin X, Qiu Y, Zhao C, Zhou Z, Bao J, Qian W. The Role of Amyloid-Beta and Tau in the Early Pathogenesis of Alzheimer's Disease. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research. 27: e933084. PMID 34471085 DOI: 10.12659/MSM.933084   
2021 Festa BP, Barbosa AD, Rob M, Rubinsztein DC. The pleiotropic roles of autophagy in Alzheimer's disease: From pathophysiology to therapy. Current Opinion in Pharmacology. 60: 149-157. PMID 34419832 DOI: 10.1016/j.coph.2021.07.011   
2021 Grundman J, Spencer B, Sarsoza F, Rissman RA. Transcriptome analyses reveal tau isoform-driven changes in transposable element and gene expression. Plos One. 16: e0251611. PMID 34587152 DOI: 10.1371/journal.pone.0251611   
2021 Wu C, Zhao J, Wu Q, Tan Q, Liu Q, Xiao S. Tau -Terminal Inserts Regulate Tau Liquid-Liquid Phase Separation and Condensates Maturation in a Neuronal Cell Model. International Journal of Molecular Sciences. 22. PMID 34575888 DOI: 10.3390/ijms22189728   
2021 Dai S, Zhou F, Sun J, Li Y. NPD1 Enhances Autophagy and Reduces Hyperphosphorylated Tau and Amyloid-β42 by Inhibiting GSK3β Activation in N2a/APP695swe Cells. Journal of Alzheimer's Disease : Jad. PMID 34602482 DOI: 10.3233/JAD-210729   
2021 Hou Z, Wydorski PM, Perez VA, Mendoza-Oliva A, Ryder BD, Mirbaha H, Kashmer O, Joachimiak LA. DnaJC7 binds natively folded structural elements in tau to inhibit amyloid formation. Nature Communications. 12: 5338. PMID 34504072 DOI: 10.1038/s41467-021-25635-y   
2021 Ebenau JL, van der Lee SJ, Hulsman M, Tesi N, Jansen IE, Verberk IMW, van Leeuwenstijn M, Teunissen CE, Barkhof F, Prins ND, Scheltens P, Holstege H, van Berckel BNM, van der Flier WM. Risk of dementia in ε4 carriers is mitigated by a polygenic risk score. Alzheimer's & Dementia (Amsterdam, Netherlands). 13: e12229. PMID 34541285 DOI: 10.1002/dad2.12229   
2021 Seo EH, Lim HJ, Yoon HJ, Choi KY, Lee JJ, Park JY, Choi SH, Kim H, Kim BC, Lee KH. Visuospatial memory impairment as a potential neurocognitive marker to predict tau pathology in Alzheimer's continuum. Alzheimer's Research & Therapy. 13: 167. PMID 34627371 DOI: 10.1186/s13195-021-00909-1   
2021 Li S, Wang C, Wang Z, Tan J. Involvement of cerebrovascular abnormalities in the pathogenesis and progression of Alzheimer's disease: an adrenergic approach. Aging. 13. PMID 34479211 DOI: 10.18632/aging.203482   
2021 Wang H, Zhang Y, Zheng C, Yang S, Chen X, Wang H, Gao S. A 3-Gene-Based Diagnostic Signature in Alzheimer's Disease. European Neurology. 1-8. PMID 34521086 DOI: 10.1159/000518727   
2021 Chen SD, Lu JY, Li HQ, Yang YX, Jiang JH, Cui M, Zuo CT, Tan L, Dong Q, Yu JT, . Staging tau pathology with tau PET in Alzheimer's disease: a longitudinal study. Translational Psychiatry. 11: 483. PMID 34537810 DOI: 10.1038/s41398-021-01602-5   
2021 Sun Y, Xu S, Jiang M, Liu X, Yang L, Bai Z, Yang Q. Role of the Extracellular Matrix in Alzheimer's Disease. Frontiers in Aging Neuroscience. 13: 707466. PMID 34512308 DOI: 10.3389/fnagi.2021.707466   
2021 Chatterjee P, Pedrini S, Ashton NJ, Tegg M, Goozee K, Singh AK, Karikari TK, Simrén J, Vanmechelen E, Armstrong NJ, Hone E, Asih PR, Taddei K, Doré V, Villemagne VL, et al. Diagnostic and prognostic plasma biomarkers for preclinical Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 34494715 DOI: 10.1002/alz.12447   
2021 Cardona K, Medina J, Orrego-Cardozo M, Restrepo de Mejía F, Elcoroaristizabal X, Naranjo Galvis CA. Inflammatory gene expression profiling in peripheral blood from patients with Alzheimer's disease reveals key pathways and hub genes with potential diagnostic utility: a preliminary study. Peerj. 9: e12016. PMID 34484988 DOI: 10.7717/peerj.12016   
2021 Pelkmans W, Ossenkoppele R, Dicks E, Strandberg O, Barkhof F, Tijms BM, Pereira JB, Hansson O. Tau-related grey matter network breakdown across the Alzheimer's disease continuum. Alzheimer's Research & Therapy. 13: 138. PMID 34389066 DOI: 10.1186/s13195-021-00876-7   
2021 D'Andrea L, Stringhi R, Di Luca M, Marcello E. Looking at Alzheimer's Disease Pathogenesis from the Nuclear Side. Biomolecules. 11. PMID 34572474 DOI: 10.3390/biom11091261   
2021 Sexton C, Snyder H, Beher D, Boxer AL, Brannelly P, Brion JP, Buée L, Cacace AM, Chételat G, Citron M, DeVos SL, Diaz K, Feldman HH, Frost B, Goate AM, et al. Current directions in tau research: Highlights from Tau 2020. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 34581500 DOI: 10.1002/alz.12452   
2021 Kang SG, Han ZZ, Daude N, McNamara E, Wohlgemuth S, Molina-Porcel L, Safar JG, Mok SA, Westaway D. Pathologic tau conformer ensembles induce dynamic, liquid-liquid phase separation events at the nuclear envelope. Bmc Biology. 19: 199. PMID 34503506 DOI: 10.1186/s12915-021-01132-y   
2021 Makwana KM, Sarnowski MP, Miao J, Lin YS, Del Valle JR. N-Amination Converts Amyloidogenic Tau Peptides into Soluble Antagonists of Cellular Seeding. Acs Chemical Neuroscience. PMID 34609825 DOI: 10.1021/acschemneuro.1c00528   
2021 Song Z, Qu Y, Xu Y, Zhang L, Zhou L, Han Y, Zhao W, Yu P, Zhang Y, Li X, Qin C. Microarray microRNA profiling of urinary exosomes in a 5XFAD mouse model of Alzheimer's disease. Animal Models and Experimental Medicine. 4: 233-242. PMID 34557649 DOI: 10.1002/ame2.12175   
2021 Shi Y, Zhang W, Yang Y, Murzin AG, Falcon B, Kotecha A, van Beers M, Tarutani A, Kametani F, Garringer HJ, Vidal R, Hallinan GI, Lashley T, Saito Y, Murayama S, et al. Structure-based classification of tauopathies. Nature. PMID 34588692 DOI: 10.1038/s41586-021-03911-7   
2021 Mroczek K, Fernando S, Fisher PR, Annesley SJ. Interactions and Cytotoxicity of Human Neurodegeneration- Associated Proteins Tau and α-Synuclein in the Simple Model . Frontiers in Cell and Developmental Biology. 9: 741662. PMID 34552934 DOI: 10.3389/fcell.2021.741662   
2021 Fernandes AR, Dujardin S, Maté de Gérando A, Hyman BT, Frosch MP. Impact of Sterilization Methods on the Seeding Ability of Human Tau Proteopathic Seeds. Journal of Neuropathology and Experimental Neurology. PMID 34498073 DOI: 10.1093/jnen/nlab087   
2021 Setti SE, Reed MN. Network activity changes in the pathophysiology of Alzheimer's disease: the role of aging and early entorhinal cortex dysfunction. Metabolic Brain Disease. PMID 34591222 DOI: 10.1007/s11011-021-00848-8   
2021 Leveille E, Ross OA, Gan-Or Z. Tau and MAPT genetics in tauopathies and synucleinopathies. Parkinsonism & Related Disorders. PMID 34593302 DOI: 10.1016/j.parkreldis.2021.09.008   
2021 Arias JC, Edwards M, Vitali F, Beach TG, Serrano GE, Weinkauf CC. Extracranial carotid atherosclerosis is associated with increased neurofibrillary tangle accumulation. Journal of Vascular Surgery. PMID 34478810 DOI: 10.1016/j.jvs.2021.07.238   
2021 Pradeepkiran JA, Munikumar M, Reddy AP, Reddy PH. Protective effects of a small molecule inhibitor ligand against hyperphosphorylated tau-induced mitochondrial and synaptic toxicities in Alzheimer disease. Human Molecular Genetics. PMID 34432046 DOI: 10.1093/hmg/ddab244   
2021 Armijo E, Edwards G, Flores A, Vera J, Shahnawaz M, Moda F, Gonzalez C, Sanhueza M, Soto C. Induced Pluripotent Stem Cell-Derived Neural Precursors Improve Memory, Synaptic and Pathological Abnormalities in a Mouse Model of Alzheimer's Disease. Cells. 10. PMID 34359972 DOI: 10.3390/cells10071802   
2021 Zhang Y, Zhang Y, Aman Y, Ng CT, Chau WH, Zhang Z, Yue M, Bohm C, Jia Y, Li S, Yuan Q, Griffin J, Chiu K, Wong DSM, Wang B, et al. Amyloid-β toxicity modulates tau phosphorylation through the PAX6 signalling pathway. Brain : a Journal of Neurology. PMID 34428276 DOI: 10.1093/brain/awab134   
2021 Potashman M, Buessing M, Levitchi Benea M, Cummings J, Borson S, Pemberton-Ross P, Epstein AJ. Estimating Progression Rates Across the Spectrum of Alzheimer's Disease for Amyloid-Positive Individuals Using National Alzheimer's Coordinating Center Data. Neurology and Therapy. PMID 34431074 DOI: 10.1007/s40120-021-00272-1