| Year |
Citation |
Score |
| 2011 |
Exton JH. Glucagon Signal-Transduction Mechanisms Comprehensive Physiology. 435-450. DOI: 10.1002/Cphy.Cp070213 |
0.361 |
|
| 2011 |
Exton JH. Phospholipid‐Derived Second Messengers Comprehensive Physiology. 255-291. DOI: 10.1002/Cphy.Cp070111 |
0.334 |
|
| 2007 |
Brown HA, Henage LG, Preininger AM, Xiang Y, Exton JH. Biochemical Analysis of Phospholipase D Methods in Enzymology. 434: 49-87. PMID 17954242 DOI: 10.1016/S0076-6879(07)34004-4 |
0.302 |
|
| 2006 |
Hu P, Han Z, Couvillon AD, Kaufman RJ, Exton JH. Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1α-mediated NF-κB activation and down-regulation of TRAF2 expression Molecular and Cellular Biology. 26: 3071-3084. PMID 16581782 DOI: 10.1128/Mcb.26.8.3071-3084.2006 |
0.728 |
|
| 2006 |
Shin OH, Exton JH. Assays and properties of arfaptin 2 binding to Rac1 and ADP-ribosylation factors (Arfs) Methods in Enzymology. 404: 359-367. PMID 16413282 DOI: 10.1016/S0076-6879(05)04031-0 |
0.354 |
|
| 2006 |
Henage LG, Exton JH, Brown HA. Kinetic analysis of a mammalian phospholipase D: Allosteric modulation by monomeric GTPases, protein kinase C, and polyphosphoinositides Journal of Biological Chemistry. 281: 3408-3417. PMID 16339153 DOI: 10.1074/Jbc.M508800200 |
0.434 |
|
| 2006 |
Couvillon AD, Exton JH. Role of heterotrimeric G-proteins in lysophosphatidic acid-mediated neurite retraction by RhoA-dependent and -independent mechanisms in N1E-115 cells Cellular Signalling. 18: 715-728. PMID 16122906 DOI: 10.1016/J.Cellsig.2005.06.012 |
0.738 |
|
| 2005 |
Chen JS, Exton JH. Sites on phospholipase D2 phosphorylated by PKCα Biochemical and Biophysical Research Communications. 333: 1322-1326. PMID 15979581 DOI: 10.1016/J.Bbrc.2005.06.048 |
0.362 |
|
| 2005 |
Hu T, Exton JH. A point mutation at phenylalanine 663 abolishes protein kinase Cα's ability to translocate to the perinuclear region and activate phospholipase D1 Biochemical and Biophysical Research Communications. 333: 750-753. PMID 15963950 DOI: 10.1016/J.Bbrc.2005.05.184 |
0.375 |
|
| 2005 |
Kook S, Exton JH. Identification of interaction sites of protein kinase Cα on phospholipase D1 Cellular Signalling. 17: 1423-1432. PMID 15951158 DOI: 10.1016/J.Cellsig.2005.03.003 |
0.341 |
|
| 2005 |
Hiroyama M, Exton JH. Localization and regulation of phospholipase D2 by ARF6 Journal of Cellular Biochemistry. 95: 149-164. PMID 15759270 DOI: 10.1002/Jcb.20351 |
0.384 |
|
| 2005 |
Ho WT, Xie Z, Zhao ZJ, Exton JH. Tyrosine phosphorylation of phospholipase D1 by v-Src does not per se result in activation Cellular Signalling. 17: 691-699. PMID 15722193 DOI: 10.1016/J.Cellsig.2004.10.007 |
0.38 |
|
| 2005 |
Buchanan FG, McReynolds M, Couvillon A, Kam Y, Holla VR, DuBois RN, Exton JH. Requirement of phospholipase D1 activity in H-RasV12-induced transformation Proceedings of the National Academy of Sciences of the United States of America. 102: 1638-1642. PMID 15668389 DOI: 10.1073/Pnas.0406698102 |
0.729 |
|
| 2005 |
Hu T, Exton JH. 1-Butanol interferes with phospholipase D1 and protein kinase Cα association and inhibits phospholipase D1 basal activity Biochemical and Biophysical Research Communications. 327: 1047-1051. PMID 15652502 DOI: 10.1016/J.Bbrc.2004.12.117 |
0.415 |
|
| 2005 |
Hiroyama M, Exton JH. Studies of the roles of ADP-ribosylation factors and phospholipase D in phorbol ester-induced membrane ruffling Journal of Cellular Physiology. 202: 608-622. PMID 15389577 DOI: 10.1002/Jcp.20156 |
0.41 |
|
| 2004 |
Hu P, Han Z, Couvillon AD, Exton JH. Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death Journal of Biological Chemistry. 279: 49420-49429. PMID 15339911 DOI: 10.1074/Jbc.M407700200 |
0.728 |
|
| 2004 |
Hu T, Exton JH. Protein kinase Cα translocates to the perinuclear region to activate phospholipase D1 Journal of Biological Chemistry. 279: 35702-35708. PMID 15187091 DOI: 10.1074/Jbc.M402372200 |
0.423 |
|
| 2004 |
Chen JS, Exton JH. Regulation of phospholipase D2 activity by protein kinase Cα Journal of Biological Chemistry. 279: 22076-22083. PMID 15031293 DOI: 10.1074/Jbc.M311033200 |
0.416 |
|
| 2004 |
Kam Y, Exton JH. Role of phospholipase D in the activation of protein kinase D by lysophosphatidic acid Biochemical and Biophysical Research Communications. 315: 139-143. PMID 15013437 DOI: 10.1016/J.Bbrc.2004.01.034 |
0.389 |
|
| 2004 |
Kam Y, Exton JH. Role of phospholipase D1 in the regulation of mTOR activity by lysophosphatidic acid Faseb Journal. 18: 311-319. PMID 14769825 DOI: 10.1096/Fj.03-0731Com |
0.413 |
|
| 2004 |
Exton JH. Mammalian phospholipase D - properties and regulation Advances in Molecular and Cell Biology. 33: 451-462. DOI: 10.1016/S1569-2558(03)33022-X |
0.322 |
|
| 2003 |
Ho WT, Exton JH, Williger BT. Arfaptin 1 inhibits ADP-ribosylation factor-dependent matrix metalloproteinase-9 secretion induced by phorbol ester in HT 1080 fibrosarcoma cells Febs Letters. 537: 91-95. PMID 12606037 DOI: 10.1016/S0014-5793(03)00098-X |
0.326 |
|
| 2003 |
Hu T, Exton JH. Mechanisms of regulation of phospholipase D1 by protein kinase Ca Journal of Biological Chemistry. 278: 2348-2355. PMID 12431982 DOI: 10.1074/Jbc.M210093200 |
0.415 |
|
| 2002 |
Exton JH. Regulation of phospholipase D. Febs Letters. 531: 58-61. PMID 12401203 DOI: 10.1016/S0014-5793(02)03405-1 |
0.389 |
|
| 2002 |
Xie Z, Ho WT, Exton JH. Functional implications of post-translational modifications of phospholipases D1 and D2 Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids. 1580: 9-21. PMID 11923096 DOI: 10.1016/S1388-1981(01)00168-8 |
0.377 |
|
| 2002 |
Xie Z, Ho WT, Spellman R, Cai S, Exton JH. Mechanisms of regulation of phospholipase D1 and D2 by the heterotrimeric G proteins G13 and Gq Journal of Biological Chemistry. 277: 11979-11986. PMID 11812783 DOI: 10.1074/Jbc.M109751200 |
0.391 |
|
| 2002 |
Kam Y, Exton JH. Dimerization of phospholipase D isozymes Biochemical and Biophysical Research Communications. 290: 375-380. PMID 11779179 DOI: 10.1006/Bbrc.2001.6146 |
0.338 |
|
| 2001 |
Xie Z, Kim HK, Exton JH. Expression and characterization of rat brain Phospholipase D Methods in Enzymology. 345: 255-264. PMID 11665609 DOI: 10.1016/S0076-6879(02)45021-5 |
0.396 |
|
| 2001 |
Shin OH, Couvillon AD, Exton JH. Arfophilin is a common target of both class II and class III ADP-ribosylation factors. Biochemistry. 40: 10846-52. PMID 11535061 DOI: 10.1021/Bi0107391 |
0.728 |
|
| 2001 |
Shin OH, Exton JH. Differential binding of arfaptin 2/POR1 to ADP-ribosylation factors and Rac1 Biochemical and Biophysical Research Communications. 285: 1267-1273. PMID 11478794 DOI: 10.1006/Bbrc.2001.5330 |
0.327 |
|
| 2001 |
Kam Y, Exton JH. Phospholipase D activity is required for actin stress fiber formation in fibroblasts Molecular and Cellular Biology. 21: 4055-4066. PMID 11359912 DOI: 10.1128/Mcb.21.12.4055-4066.2001 |
0.374 |
|
| 2001 |
Cai S, Exton JH. Determination of interaction sites of phospholipase D1 for RhoA Biochemical Journal. 355: 779-785. PMID 11311142 DOI: 10.1042/Bj3550779 |
0.376 |
|
| 2001 |
Xie Z, Ho WT, Exton JH. Requirements and effects of palmitoylation of rat PLD1. The Journal of Biological Chemistry. 276: 9383-91. PMID 11121416 DOI: 10.1074/Jbc.M009425200 |
0.385 |
|
| 2000 |
Xie Z, Ho WT, Exton JH. Conserved amino acids at the C-terminus of rat phospholipase D1 are essential for enzymatic activity European Journal of Biochemistry. 267: 7138-7146. PMID 11106425 DOI: 10.1046/J.1432-1327.2000.01816.X |
0.339 |
|
| 2000 |
Oh SO, Hong JH, Kim YR, Yoo HS, Lee SH, Lim K, Hwang BD, Exton JH, Park SK. Regulation of phospholipase D2 by H2O2 in PC12 cells Journal of Neurochemistry. 75: 2445-2454. PMID 11080196 DOI: 10.1046/J.1471-4159.2000.0752445.X |
0.379 |
|
| 2000 |
Jin S, Exton JH. Activation of RhoA by association of Gα13 with Dbl Biochemical and Biophysical Research Communications. 277: 718-721. PMID 11062019 DOI: 10.1006/Bbrc.2000.3744 |
0.385 |
|
| 2000 |
Xie Z, Ho WT, Exton JH. Association of the N- and C-terminal domains of phospholipase D. Contribution of the conserved HKD motifs to the interaction and the requirement of the association for Ser/Thr phosphorylation of the enzyme Journal of Biological Chemistry. 275: 24962-24969. PMID 10825182 DOI: 10.1074/Jbc.M909745199 |
0.34 |
|
| 2000 |
Buchanan FG, Elliot CM, Gibbs M, Exton JH. Translocation of the Rac1 guanine nucleotide exchange factor Tiam1 induced by platelet-derived growth factor and lysophosphatidic acid Journal of Biological Chemistry. 275: 9742-9748. PMID 10734127 DOI: 10.1074/Jbc.275.13.9742 |
0.419 |
|
| 2000 |
Hess JA, Buchanan FG, Ryder S, Exton JH. Altered activation of phospholipase D by lysophosphatidic acid and endothelin-1 in mouse embryo fibroblasts lacking phospholipase C-γ1 Cellular Signalling. 12: 37-45. PMID 10676846 DOI: 10.1016/S0898-6568(99)00075-3 |
0.39 |
|
| 1999 |
Shin OH, Ross AH, Mihai I, Exton JH. Identification of arfophilin, a target protein for GTP-bound class II ADP-ribosylation factors. The Journal of Biological Chemistry. 274: 36609-15. PMID 10593962 DOI: 10.1074/Jbc.274.51.36609 |
0.328 |
|
| 1999 |
Exton JH. Regulation of phospholipase D. Biochimica Et Biophysica Acta. 1439: 121-33. PMID 10425390 DOI: 10.1016/S1388-1981(99)00089-X |
0.427 |
|
| 1999 |
Williger BT, Provost JJ, Ho WT, Milstine J, Exton JH. Arfaptin 1 forms a complex with ADP-ribosylation factor and inhibits phospholipase D. Febs Letters. 454: 85-9. PMID 10413101 DOI: 10.1016/S0014-5793(99)00771-1 |
0.717 |
|
| 1999 |
Fleming IN, Elliott CM, Buchanan FG, Downes CP, Exton JH. Ca2+/calmodulin-dependent protein kinase II regulates Tiam1 by reversible protein phosphorylation Journal of Biological Chemistry. 274: 12753-12758. PMID 10212259 DOI: 10.1074/Jbc.274.18.12753 |
0.375 |
|
| 1999 |
Williger BT, Ostermann J, Exton JH. Arfaptin 1, an ARF-binding protein, inhibits phospholipase D and endoplasmic reticulum/Golgi protein transport Febs Letters. 443: 197-200. PMID 9989604 DOI: 10.1016/S0014-5793(98)01707-4 |
0.397 |
|
| 1999 |
Williger BT, Ho WT, Exton JH. Phospholipase D mediates matrix metalloproteinase-9 secretion in phorbol ester-stimulated human fibrosarcoma cells Journal of Biological Chemistry. 274: 735-738. PMID 9873009 DOI: 10.1074/Jbc.274.2.735 |
0.358 |
|
| 1998 |
Xie Z, Ho WT, Exton JH. Association of N- and C-terminal domains of phospholipase D is required for catalytic activity Journal of Biological Chemistry. 273: 34679-34682. PMID 9856987 DOI: 10.1074/Jbc.273.52.34679 |
0.321 |
|
| 1998 |
Min DS, Kim EG, Exton JH. Involvement of tyrosine phosphorylation and protein kinase C in the activation of phospholipase D by H2O2 in Swiss 3T3 fibroblasts. The Journal of Biological Chemistry. 273: 29986-94. PMID 9792719 DOI: 10.1074/Jbc.273.45.29986 |
0.424 |
|
| 1998 |
Guillemain I, Exton JH. Role of Rho proteins in agonist regulation of phospholipase D in HL-60 cells Biochimica Et Biophysica Acta - Molecular Cell Research. 1405: 161-170. PMID 9784628 DOI: 10.1016/S0167-4889(98)00107-4 |
0.449 |
|
| 1998 |
Min DS, Exton JH. Phospholipase D is associated in a phorbol ester-dependent manner with protein kinase c-α and with a 220-kDa protein which is phosphorylated on serine and threonine Biochemical and Biophysical Research Communications. 248: 533-537. PMID 9703960 DOI: 10.1006/Bbrc.1998.8990 |
0.418 |
|
| 1998 |
Tsai SC, Adamik R, Hong JX, Moss J, Vaughan M, Kanoh H, Exton JH. Effects of arfaptin 1 on guanine nucleotide-dependent activation of phospholipase D and cholera toxin by ADP-ribosylation factor Journal of Biological Chemistry. 273: 20697-20701. PMID 9694811 DOI: 10.1074/Jbc.273.33.20697 |
0.41 |
|
| 1998 |
Hess JA, Ji QS, Carpenter G, Exton JH. Analysis of platelet-derived growth factor-induced phospholipase D activation in mouse embryo fibroblasts lacking phospholipase C-γ1 Journal of Biological Chemistry. 273: 20517-20524. PMID 9685408 DOI: 10.1074/Jbc.273.32.20517 |
0.418 |
|
| 1998 |
Fleming IN, Elliott CM, Exton JH. Phospholipase C-γ, protein kinase C and Ca2+/calmodulin-dependent protein kinase II are involved in platelet-derived growth factor-induced phosphorylation of tiam1 Febs Letters. 429: 229-233. PMID 9662423 DOI: 10.1016/S0014-5793(98)00566-3 |
0.368 |
|
| 1998 |
Bae CD, Min DS, Fleming IN, Exton JH. Determination of interaction sites on the small G protein RhoA for phospholipase D Journal of Biological Chemistry. 273: 11596-11604. PMID 9565577 DOI: 10.1074/Jbc.273.19.11596 |
0.337 |
|
| 1998 |
Park SK, Min DS, Exton JH. Definition of the protein kinase C interaction site of phospholipase D Biochemical and Biophysical Research Communications. 244: 364-367. PMID 9514932 DOI: 10.1006/Bbrc.1998.8275 |
0.39 |
|
| 1998 |
Min DS, Park SK, Exton JH. Characterization of a rat brain phospholipase D isozyme Journal of Biological Chemistry. 273: 7044-7051. PMID 9507013 DOI: 10.1074/Jbc.273.12.7044 |
0.457 |
|
| 1998 |
Plonk SG, Park SK, Exton JH. The α-subunit of the heterotrimeric G protein G13 activates a phospholipase D isozyme by a pathway requiring Rho family GTPases Journal of Biological Chemistry. 273: 4823-4826. PMID 9478920 DOI: 10.1074/Jbc.273.9.4823 |
0.402 |
|
| 1997 |
Exton JH. Regulation of phosphoinositide phospholipases by G-proteins Advances in Experimental Medicine and Biology. 400: 3-8. PMID 9547530 DOI: 10.1007/978-1-4615-5325-0_1 |
0.415 |
|
| 1997 |
Fleming IN, Elliott CM, Collard JG, Exton JH. Lysophosphatidic acid induces threonine phosphorylation of Tiam1 in Swiss 3T3 fibroblasts via activation of protein kinase C. The Journal of Biological Chemistry. 272: 33105-10. PMID 9407095 DOI: 10.1074/Jbc.272.52.33105 |
0.396 |
|
| 1997 |
Guillemain I, Exton JH. Effects of brefeldin A on phosphatidylcholine phospholipase D and inositolphospholipid metabolism in HL-60 cells European Journal of Biochemistry. 249: 812-819. PMID 9395331 DOI: 10.1111/J.1432-1033.1997.00812.X |
0.436 |
|
| 1997 |
Park SK, Provost JJ, Bae CD, Ho WT, Exton JH. Cloning and characterization of phospholipase D from rat brain. The Journal of Biological Chemistry. 272: 29263-71. PMID 9361006 DOI: 10.1074/Jbc.272.46.29263 |
0.727 |
|
| 1997 |
Sano T, Ohyama K, Yamano Y, Nakagomi Y, Nakazawa S, Kikyo M, Shirai H, Blank JS, Exton JH, Inagami T. A domain for G protein coupling in carboxyl-terminal tail of rat angiotensin II receptor type 1A Journal of Biological Chemistry. 272: 23631-23636. PMID 9295303 DOI: 10.1074/Jbc.272.38.23631 |
0.329 |
|
| 1997 |
Yeo EJ, Provost JJ, Exton JH. Dissociation of tyrosine phosphorylation and activation of phosphoinositide phospholipase C induced by the protein kinase C inhibitor Ro-31-8220 in Swiss 3T3 cells treated with platelet-derived growth factor. Biochimica Et Biophysica Acta. 1356: 308-20. PMID 9194574 DOI: 10.1016/S0167-4889(97)00006-2 |
0.719 |
|
| 1997 |
Exton JH. Phospholipase D: Enzymology, mechanisms of regulation, and function Physiological Reviews. 77: 303-320. PMID 9114816 DOI: 10.1152/Physrev.1997.77.2.303 |
0.43 |
|
| 1997 |
Vinggaard AM, Provost JJ, Exton JH, Hansen HS. Arf and RhoA regulate both the cytosolic and the membrane-bound phospholipase D from human placenta. Cellular Signalling. 9: 189-96. PMID 9113419 DOI: 10.1016/S0898-6568(96)00140-4 |
0.726 |
|
| 1997 |
Kanoh H, Williger BT, Exton JH. Arfaptin 1, a putative cytosolic target protein of ADP-ribosylation factor, is recruited to golgi membranes Journal of Biological Chemistry. 272: 5421-5429. PMID 9038142 DOI: 10.1074/Jbc.272.9.5421 |
0.346 |
|
| 1997 |
Exton JH. Cell signalling through guanine-nucleotide-binding regulatory proteins (G proteins) and phospholipases European Journal of Biochemistry. 243: 10-20. PMID 9030716 DOI: 10.1111/J.1432-1033.1997.T01-1-00010.X |
0.411 |
|
| 1997 |
Mitsui H, Takuwa N, Kurokawa K, Exton JH, Takuwa Y. Dependence of activated Gα12-induced G1 to S phase cell cyclin progression on both Ras/mitogen-activated protein kinase and Ras/Rac1/Jun N- terminal kinase cascades in NIH3T3 fibroblasts Journal of Biological Chemistry. 272: 4904-4910. PMID 9030549 DOI: 10.1074/Jbc.272.8.4904 |
0.375 |
|
| 1997 |
Hess JA, Ross AH, Qiu RG, Symons M, Exton JH. Role of Rho family proteins in phospholipase D activation by growth factors Journal of Biological Chemistry. 272: 1615-1620. PMID 8999836 DOI: 10.1074/Jbc.272.3.1615 |
0.393 |
|
| 1996 |
Fleming IN, Elliott CM, Exton JH. Differential translocation of Rho family GTPases by lysophosphatidic acid, endothelin-1, and platelet-derived growth factor Journal of Biological Chemistry. 271: 33067-33073. PMID 8955154 DOI: 10.1074/Jbc.271.51.33067 |
0.412 |
|
| 1996 |
Provost JJ, Fudge J, Israelit S, Siddiqi AR, Exton JH. Tissue-specific distribution and subcellular distribution of phospholipase D in rat: evidence for distinct RhoA- and ADP-ribosylation factor (ARF)-regulated isoenzymes. The Biochemical Journal. 319: 285-91. PMID 8870680 DOI: 10.1042/Bj3190285 |
0.719 |
|
| 1996 |
Malcolm KC, Sable CL, Elliott CM, Exton JH. Enhanced phospholipase D activity and altered morphology in RhoA-overexpressing Rat1 fibroblasts Biochemical and Biophysical Research Communications. 225: 514-519. PMID 8753793 DOI: 10.1006/Bbrc.1996.1204 |
0.44 |
|
| 1996 |
Pete MJ, Exton JH. Purification of a lysophospholipase from bovine brain that selectively deacylates arachidonoyl-substituted lysophosphatidylcholine Journal of Biological Chemistry. 271: 18114-18121. PMID 8663471 DOI: 10.1074/Jbc.271.30.18114 |
0.319 |
|
| 1996 |
Malcolm KC, Elliott CM, Exton JH. Evidence for Rho-mediated agonist stimulation of phospholipase D in rat1 fibroblasts. Effects of Clostridium botulinum C3 exoenzyme. The Journal of Biological Chemistry. 271: 13135-9. PMID 8662844 DOI: 10.1074/Jbc.271.22.13135 |
0.419 |
|
| 1996 |
Venkatakrishnan G, Exton JH. Identification of determinants in the α-subunit of Gq required for phospholipase C activation Journal of Biological Chemistry. 271: 5066-5072. PMID 8617784 DOI: 10.1074/Jbc.271.9.5066 |
0.33 |
|
| 1996 |
Pete MJ, Wu DW, Exton JH. Subcellular fractions of bovine brain degrade phosphatidylcholine by sequential deacylation of the sn-1 and sn-2 positions Biochimica Et Biophysica Acta - Lipids and Lipid Metabolism. 1299: 325-332. PMID 8597587 DOI: 10.1016/0005-2760(95)00225-1 |
0.312 |
|
| 1995 |
Yeo EJ, Exton JH. Stimulation of phospholipase D by epidermal growth factor requires protein kinase C activation in Swiss 3T3 cells Journal of Biological Chemistry. 270: 3980-3988. PMID 7876145 DOI: 10.1074/Jbc.270.8.3980 |
0.445 |
|
| 1995 |
Chen J, DeVivo M, Dingus J, Harry A, Li J, Sui J, Carty DJ, Blank JL, Exton JH, Stoffel RH, Inglese J, Lefkowitz RJ, Logothetis DE, Hildebrandt JD, Iyengar R. A region of adenylyl cyclase 2 critical for regulation by G protein βγ subunits Science. 268: 1166-1169. PMID 7761832 DOI: 10.1126/Science.7761832 |
0.307 |
|
| 1995 |
Siddiqi AR, Smith JL, Ross AH, Qiu RG, Symons M, Exton JH. Regulation of phospholipase D in HL60 cells: Evidence for a cytosolic phospholipase D Journal of Biological Chemistry. 270: 8466-8473. PMID 7721742 DOI: 10.1074/Jbc.270.15.8466 |
0.432 |
|
| 1995 |
Malcolm KC, Trammell SE, Exton JH. Purinergic agonist and G protein stimulation of phospholipase D in rat liver plasma membranes. Independence from phospholipase C activation Bba - Molecular Cell Research. 1268: 152-158. PMID 7662702 DOI: 10.1016/0167-4889(95)00073-2 |
0.415 |
|
| 1994 |
Caro JF, Raju MS, Caro M, Lynch CJ, Poulos J, Exton JH, Thakkar JK. Guanine nucleotide binding regulatory proteins in liver from obese humans with and without type II diabetes: Evidence for altered 'cross-talk' between the insulin receptor and G(i)-proteins Journal of Cellular Biochemistry. 54: 309-319. PMID 8200911 DOI: 10.1002/Jcb.240540307 |
0.314 |
|
| 1994 |
Exton JH. Phosphatidylcholine breakdown and signal transduction Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 1212: 26-42. PMID 8155724 DOI: 10.1016/0005-2760(94)90186-4 |
0.427 |
|
| 1994 |
Conricode KM, Smith JL, Burns DJ, Exton JH. Phospholipase D activation in fibroblast membranes by the α and β isoforms of protein kinase C Febs Letters. 342: 149-153. PMID 8143868 DOI: 10.1016/0014-5793(94)80490-7 |
0.407 |
|
| 1994 |
Exton JH. Messenger molecules derived from membrane lipids Current Opinion in Cell Biology. 6: 226-229. PMID 8024814 DOI: 10.1016/0955-0674(94)90140-6 |
0.318 |
|
| 1994 |
Exton JH. Phosphoinositide phospholipases and G proteins in hormon action Annual Review of Physiology. 56: 349-369. PMID 8010744 DOI: 10.1146/Annurev.Ph.56.030194.002025 |
0.303 |
|
| 1994 |
Yeo EJ, Kazlauskas A, Exton JH. Activation of phospholipase C-gamma is necessary for stimulation of phospholipase D by platelet-derived growth factor. The Journal of Biological Chemistry. 269: 27823-6. PMID 7961710 |
0.326 |
|
| 1994 |
Ha KS, Yeo EJ, Exton JH. Lysophosphatidic acid activation of phosphatidylcholine-hydrolysing phospholipase D and actin polymerization by a pertussis toxin sensitive mechanism Biochemical Journal. 303: 55-59. PMID 7945265 DOI: 10.1042/Bj3030055 |
0.361 |
|
| 1994 |
Blank JL, Exton JH. [14] Purification of activated and heterotrimeric forms of G(q) proteins Methods in Enzymology. 237: 174-181. PMID 7934995 DOI: 10.1016/S0076-6879(94)37061-3 |
0.355 |
|
| 1994 |
Malcolm KC, Ross AH, Qiut RG, Symonst M, Exton JH. Activation of rat liver phospholipase D by the small GTP-binding protein RhoA Journal of Biological Chemistry. 269: 25951-25954. PMID 7929302 |
0.32 |
|
| 1993 |
Allan CJ, Exton JH. Quantification of inositol phospholipid breakdown in isolated rat hepatocytes. The Biochemical Journal. 290: 865-72. PMID 8384449 DOI: 10.1042/Bj2900865 |
0.318 |
|
| 1993 |
Nakanishi H, Brewer KA, Exton JH. Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate. The Journal of Biological Chemistry. 268: 13-6. PMID 8380153 |
0.302 |
|
| 1993 |
Ha KS, Exton JH. Activation of actin polymerization by phosphatidic acid derived from phosphatidylcholine in IIC9 fibroblasts Journal of Cell Biology. 123: 1789-1796. PMID 8276897 DOI: 10.1083/Jcb.123.6.1789 |
0.361 |
|
| 1992 |
Conricode KM, Brewer KA, Exton JH. Activation of phospholipase D by protein kinase C. Evidence for a phosphorylation-independent mechanism Journal of Biological Chemistry. 267: 7199-7202. PMID 1559964 |
0.328 |
|
| 1992 |
Siddiqui RA, Exton JH. Oleate stimulation of diacylglycerol formation from phosphatidylcholine through effects on phospholipase D and phosphatidate phosphohydrolase. European Journal of Biochemistry / Febs. 210: 601-7. PMID 1459142 DOI: 10.1111/J.1432-1033.1992.Tb17460.X |
0.636 |
|
| 1992 |
Exton JH, Taylor SJ, Blank JS, Bocckino SB. Regulation of phosphoinositide and phosphatidylcholine phospholipases by G proteins Ciba Foundation Symposium. 164: 36-42; discussion 43. PMID 1327681 |
0.301 |
|
| 1992 |
Nakanishi H, Exton JH. Purification and characterization of the zeta isoform of protein kinase C from bovine kidney. The Journal of Biological Chemistry. 267: 16347-54. PMID 1322899 |
0.315 |
|
| 1992 |
Berstein G, Blank JL, Jhon DY, Exton JH, Rhee SG, Ross EM. Phospholipase C-beta 1 is a GTPase-activating protein for Gq/11, its physiologic regulator. Cell. 70: 411-8. PMID 1322796 DOI: 10.1016/0092-8674(92)90165-9 |
0.356 |
|
| 1992 |
Shaw K, Exton JH. Identification in bovine liver plasma membranes of a Gq-activatable phosphoinositide phospholipase C Biochemistry. 31: 6347-6354. DOI: 10.1021/Bi00142A026 |
0.399 |
|
| 1991 |
Bocckino SB, Wilson PB, Exton JH. Phosphatidate-dependent protein phosphorylation Proceedings of the National Academy of Sciences of the United States of America. 88: 6210-6213. PMID 2068102 DOI: 10.1073/Pnas.88.14.6210 |
0.37 |
|
| 1991 |
Exton JH. Some thoughts on the mechanism of action of insulin Diabetes. 40: 521-526. PMID 1902425 DOI: 10.2337/Diab.40.5.521 |
0.326 |
|
| 1991 |
Stewart SJ, Cunningham GR, Strupp JA, House FS, Kelley LL, Henderson GS, Exton JH, Bocckino SB. Activation of phospholipase D: a signaling system set in motion by perturbation of the T lymphocyte antigen receptor/CD3 complex Cell Regulation. 2: 841-850. PMID 1839358 DOI: 10.1091/Mbc.2.10.841 |
0.341 |
|
| 1991 |
Taylor SJ, Chae HZ, Rhee SG, Exton JH. Activation of the β1 isozyme of phospholipase C by α subunits of the Gq class of G proteins Nature. 350: 516-518. PMID 1707501 DOI: 10.1038/350516A0 |
0.404 |
|
| 1991 |
Exton JH, Taylor SJ, Augert G, Bocckino SB. Cell signalling through phospholipid breakdown Molecular and Cellular Biochemistry. 104: 81-86. PMID 1656198 DOI: 10.1007/978-1-4615-3886-8_11 |
0.421 |
|
| 1991 |
Taylor SJ, Exton JH. Two α subunits of the Gq class of G proteins stimulate phosphoinositide phospholipase C-β1 activity Febs Letters. 286: 214-216. PMID 1650713 DOI: 10.1016/0014-5793(91)80976-A |
0.36 |
|
| 1991 |
Blackmore PF, Mojsov S, Exton JH, Habener JF. Absence of insulinotropic glucagon-like peptide-I(7-37) receptors on isolated rat liver hepatocytes. Febs Letters. 283: 7-10. PMID 1645298 DOI: 10.1016/0014-5793(91)80541-A |
0.343 |
|
| 1990 |
Bouscarel B, Augert G, Taylor SJ, Exton JH. Alterations in vasopressin and angiotensin II receptors and responses during culture of rat liver cells Bba - Molecular Cell Research. 1055: 265-272. PMID 2265214 DOI: 10.1016/0167-4889(90)90042-C |
0.315 |
|
| 1990 |
Georgoussi Z, Taylor SJ, Bocckino SB, Exton JH. Purification of the hepatic vasopressin receptor using a novel affinity column Bba - Molecular Cell Research. 1055: 69-74. PMID 2171678 DOI: 10.1016/0167-4889(90)90092-R |
0.327 |
|
| 1989 |
Stewart SJ, Prpic V, Johns JA, Powers FS, Graber SE, Forbes JT, Exton JH. Bacterial toxins affect early events of T lymphocyte activation. The Journal of Clinical Investigation. 83: 234-42. PMID 2536043 DOI: 10.1172/Jci113865 |
0.335 |
|
| 1989 |
Lynch CJ, Blackmore PF, Johnson EH, Wange RL, Krone PK, Exton JH. Guanine nucleotide binding regulatory proteins and adenylate cyclase in livers of streptozotocin- and BB/Wor-diabetic rats. Immunodetection of G(s) and G(i) with antisera prepared against synthetic peptides Journal of Clinical Investigation. 83: 2050-2062. PMID 2498395 DOI: 10.1172/Jci114116 |
0.344 |
|
| 1988 |
Blackmore PF, Lynch CJ, Uhing RJ, Fitzgerald T, Bocckino SB, Exton JH. Role of guanine nucleotide regulatory proteins and inositol phosphates in the hormone induced mobilization of hepatocyte calcium Advances in Experimental Medicine and Biology. 232: 169-182. PMID 3145679 DOI: 10.1007/978-1-4757-0007-7_19 |
0.431 |
|
| 1988 |
Bouscarel B, Meurer K, Decker C, Exton JH. The role of protein kinase C in the inactivation of hepatic glycogen synthase by calcium-mobilizing agonists Biochemical Journal. 251: 47-53. PMID 3134012 DOI: 10.1042/Bj2510047 |
0.438 |
|
| 1988 |
Lynch CJ, Taylor SJ, Smith JA, Exton JH. Formation of the high-affinity agonist state of the α1-adrenergic receptor at cold temperatures does not require a G-protein Febs Letters. 229: 54-58. PMID 2831091 DOI: 10.1016/0014-5793(88)80796-8 |
0.302 |
|
| 1988 |
Exton JH. Mechanisms of action of calcium-mobilizing agonists: Some variations on a young theme Faseb Journal. 2: 2670-2676. PMID 2456243 DOI: 10.1096/Fasebj.2.11.2456243 |
0.391 |
|
| 1987 |
Lynch CJ, Bocckino SB, Blackmore PF, Exton JH. Calcium-mobilizing hormones and phorbol myristate acetate mediate heterologous desensitization of the hormone-sensitive hepatic Na+/K+ pump Biochemical Journal. 248: 807-813. PMID 3435486 DOI: 10.1042/Bj2480807 |
0.321 |
|
| 1987 |
Bocckino SB, Wilson PB, Exton JH. Ca2 +-mobilizing hormones elicit phosphatidylethanol accumulation via phospholipase D activation Febs Letters. 225: 201-204. PMID 3319693 DOI: 10.1016/0014-5793(87)81157-2 |
0.321 |
|
| 1987 |
Bocckino SB, Blackmore PF, Wilson PB, Exton JH. Phosphatidate accumulation in hormone-treated hepatocytes via a phospholipase D mechanism Journal of Biological Chemistry. 262: 15309-15315. PMID 3117799 |
0.33 |
|
| 1987 |
Exton JH. Mechanisms of hormonal regulation of hepatic glucose metabolism Diabetes/Metabolism Reviews. 3: 163-183. PMID 3032541 |
0.316 |
|
| 1987 |
Taylor SJ, Exton JH. Guanine-nucleotide and hormone regulation of polyphosphoinositide phospholipase C activity of rat liver plasma membranes. Bivalent-cation and phospholipid requirements Biochemical Journal. 248: 791-799. PMID 2829842 DOI: 10.1042/Bj2480791 |
0.411 |
|
| 1987 |
Exton JH. Calcium And Inositol Trisphosphate Calcium-Binding Proteins in Health and Disease. 137-145. DOI: 10.1016/B978-0-12-521040-9.50030-9 |
0.36 |
|
| 1986 |
Uhing RJ, Exton JH. Metal : ATP characteristics of insulin- and epidermal growth factor-stimulated phosphorylation in detergent extracts of rat liver plasma membranes Molecular and Cellular Endocrinology. 47: 137-143. PMID 3527812 DOI: 10.1016/0303-7207(86)90025-0 |
0.398 |
|
| 1986 |
Blackmore PF, Strickland WG, Bocckino SB, Exton JH. Mechanism of hepatic glycogen synthase inactivation induced by Ca2+-mobilizing hormones. Studies using phospholipase C and phorbol myristate acetate Biochemical Journal. 237: 235-242. PMID 3099747 DOI: 10.1042/Bj2370235 |
0.363 |
|
| 1986 |
Bouscarel B, Exton JH. Regulation of hepatic glycogen phosphorylase and glycogen synthase by calcium and diacylglycerol Bba - Molecular Cell Research. 888: 126-134. PMID 3091081 DOI: 10.1016/0167-4889(86)90078-9 |
0.362 |
|
| 1986 |
Lynch CJ, Morbach L, Blackmore PF, Exton JH. α-Subunits of Ns are released from the plasma membrane following cholera toxin activation Febs Letters. 200: 333-336. PMID 3086121 DOI: 10.1016/0014-5793(86)81163-2 |
0.353 |
|
| 1986 |
Bosch F, Bouscarel B, Slaton J, Blackmore PF, Exton JH. Epidermal growth factor mimics insulin effects in rat hepatocytes Biochemical Journal. 239: 523-530. PMID 3030262 DOI: 10.1042/Bj2390523 |
0.347 |
|
| 1986 |
Lynch CJ, Sobo GE, Exton JH. An endogenous Ca2+-sensitive proteinase converts the hepatic α1-adrenergic receptor to guanine nucleotide-insensitive forms Bba - Molecular Cell Research. 885: 110-120. PMID 2867787 DOI: 10.1016/0167-4889(86)90045-5 |
0.389 |
|
| 1985 |
Uhing RJ, Jiang H, Prpic V, Exton JH. Regulation of a liver plasma membrane phosphoinositide phosphodiesterase by guanine nucleotides and calcium Febs Letters. 188: 317-320. PMID 2993026 DOI: 10.1016/0014-5793(85)80394-X |
0.36 |
|
| 1985 |
Exton JH. Mechanisms involved in alpha-adrenergic phenomena The American Journal of Physiology. 248: E633-647. PMID 2408477 |
0.307 |
|
| 1984 |
Chrisman TD, Sobo GE, Exton JH. The Mg2+ requirements of nonactivated and activated rat liver phosphorylase kinase. Inhibition of the activated form by free Mg2+ Febs Letters. 167: 295-300. PMID 6698212 DOI: 10.1016/0014-5793(84)80146-5 |
0.36 |
|
| 1984 |
Morgan NG, Charest R, Blackmore PF, Exton JH. Potentiation of α1-adrenergic responses in rat liver by a cAMP-dependent mechanism Proceedings of the National Academy of Sciences of the United States of America. 81: 4208-4212. PMID 6330749 DOI: 10.1073/Pnas.81.13.4208 |
0.375 |
|
| 1984 |
Imazu M, Strickland WG, Exton JH. Multiple phosphorylation of rat-liver glycogen synthase by protein kinases Biochimica Et Biophysica Acta (Bba)/Protein Structure and Molecular. 789: 285-293. PMID 6089894 DOI: 10.1016/0167-4838(84)90184-5 |
0.319 |
|
| 1983 |
Morgan NG, Shipp CC, Exton JH. Studies on the mechanism of inhibition of hepatic cAMP accumulation by vasopressin Febs Letters. 163: 277-281. PMID 6315490 DOI: 10.1016/0014-5793(83)80835-7 |
0.353 |
|
| 1983 |
Morgan NG, Exton JH, Blackmore PF. Angiotensin II inhibits hepatic cAMP accumulation induced by glucagon and epinephrine and their metabolic effects Febs Letters. 153: 77-80. PMID 6298010 DOI: 10.1016/0014-5793(83)80122-7 |
0.349 |
|
| 1983 |
Morgan NG, Waynick LE, Exton JH. Characterisation of the α1-adrenergic control of hepatic cAMP in male rats European Journal of Pharmacology. 96: 1-10. PMID 6141055 DOI: 10.1016/0014-2999(83)90522-8 |
0.344 |
|
| 1982 |
Dehaye JP, Hughes BP, Blackmore PF, Exton JH. Insulin inhibition of alpha-adrenergic actions in liver. The Biochemical Journal. 194: 949-56. PMID 7030320 DOI: 10.1042/Bj1940949 |
0.335 |
|
| 1982 |
Jackowski MM, Johnson RA, Exton JH. Regulation of adrenergic stimulation of hepatic adenylate cyclase by divalent cations. Biochimica Et Biophysica Acta. 714: 74-83. PMID 6275906 DOI: 10.1016/0304-4165(82)90128-3 |
0.382 |
|
| 1982 |
Exton JH. Molecular mechanisms involved in α-adrenergic responses Trends in Pharmacological Sciences. 3: 111-115. DOI: 10.1016/0165-6147(82)91045-8 |
0.32 |
|
| 1981 |
Chiasson JL, Aylward JH, Shikama H, Exton JH. Hormonal regulation of glycogen synthase phosphorylation in perfused rat skeletal muscle Febs Letters. 127: 97-100. PMID 6788604 DOI: 10.1016/0014-5793(81)80350-X |
0.327 |
|
| 1981 |
Exton JH. Molecular mechanisms involved in alpha-adrenergic responses. Molecular and Cellular Endocrinology. 23: 233-64. PMID 6269923 DOI: 10.1016/0303-7207(81)90123-4 |
0.327 |
|
| 1981 |
Hughes BP, Blackmore PF, Exton JH. Exploration of the role of sodium in the alpha-adrenergic regulation of hepatic glycogenolysis. Febs Letters. 121: 260-4. PMID 6257547 DOI: 10.1016/0014-5793(80)80357-7 |
0.358 |
|
| 1981 |
Blackmore PF, El-Refai MF, Dehaye JP, Strickland WG, Hughes BP, Exton JH. Blockade of hepatic alpha-adrenergic receptors and responses by chlorpromazine and trifluoperazine. Febs Letters. 123: 245-8. PMID 6112163 DOI: 10.1016/0014-5793(81)80298-0 |
0.359 |
|
| 1980 |
Jackowski MM, Johnson RA, Exton JH. Calcium regulation of guanine nucleotide activation of hepatic adenylate cyclase. Biochimica Et Biophysica Acta. 630: 497-510. PMID 6772234 DOI: 10.1016/0304-4165(80)90004-5 |
0.392 |
|
| 1980 |
Steiner KE, Chan TM, Claus TH, Exton JH, Pilkis SJ. The role of phosphorylation in the alpha-adrenergic-mediated inhibition of rat hepatic pyruvate kinase. Biochimica Et Biophysica Acta. 632: 366-74. PMID 6251916 DOI: 10.1016/0304-4165(80)90232-9 |
0.389 |
|
| 1980 |
El-Refai MF, Exton JH. Subclassification of two types of alpha-adrenergic binding sites in rat liver. European Journal of Pharmacology. 62: 201-4. PMID 6247157 DOI: 10.1016/0014-2999(80)90276-9 |
0.319 |
|
| 1979 |
Blackmore PF, Dehaye JP, Strickland WG, Exton JH. alpha-Adrenergic mobilization of hepatic mitochondrial calcium. Febs Letters. 100: 117-20. PMID 437092 DOI: 10.1016/0014-5793(79)81144-8 |
0.342 |
|
| 1979 |
Taylor WM, Bygrave FL, Blackmore PF, Exton JH. Stable enhancement of ruthenium red-insensitive calcium transport in an endoplasmic reticulum-rich fraction following the exposure of isolated rat liver cells to glucagon. Febs Letters. 104: 31-4. PMID 225203 DOI: 10.1016/0014-5793(79)81079-0 |
0.303 |
|
| 1977 |
Cherrington AD, Exton JH. Studies on the role of cAMP-dependent protein kinase in the actions of glucagon and catecholamines on liver glycogen metabolism. Metabolism: Clinical and Experimental. 25: 1351-4. PMID 185493 DOI: 10.1016/S0026-0495(76)80140-0 |
0.429 |
|
| 1974 |
Pilkis SJ, Exton JH, Johnson RA, Park CR. Effects of glucagon on cyclic AMP and carbohydrate metabolism in livers from diabetic rats. Biochimica Et Biophysica Acta. 343: 250-67. PMID 4364131 DOI: 10.1016/0304-4165(74)90258-X |
0.342 |
|
| 1973 |
Exton JH, Harper SC, Tucker AL, Flagg JL, Park CR. Effects of adrenalectomy and glucocorticoid replacement on gluconeogenesis in perfused livers from diabetic rats. Biochimica Et Biophysica Acta. 329: 41-57. PMID 4361567 DOI: 10.1016/0304-4165(73)90006-8 |
0.331 |
|
| 1971 |
Exton JH, Robison GA, Sutherland EW, Park CR. Studies on the role of adenosine 3',5'-monophosphate in the hepatic actions of glucagon and catecholamines. The Journal of Biological Chemistry. 246: 6166-77. PMID 4331382 |
0.528 |
|
| 1971 |
Exton JH, Hardman JG, Williams TF, Sutherland EW, Park CR. Effects of guanosine 3',5'-monophosphate on the perfused rat liver. The Journal of Biological Chemistry. 246: 2658-64. PMID 4324220 |
0.65 |
|
| 1970 |
Exton JH, Mallette LE, Jefferson LS, Wong EH, Friedmann N, Miller TB, Park CR. The hormonal control of hepatic gluconeogenesis. Recent Progress in Hormone Research. 26: 411-61. PMID 4319350 DOI: 10.1016/B978-0-12-571126-5.50014-5 |
0.315 |
|
| 1968 |
Jefferson LS, Exton JH, Butcher RW, Sutherland EW, Park CR. Role of adenosine 3',5'-monophosphate in the effects of insulin and anti-insulin serum on liver metabolism. The Journal of Biological Chemistry. 243: 1031-8. PMID 5640968 |
0.507 |
|
| 1964 |
Exton JH, Edson NL. The antiketogenic action of sorbitol. Biochemical Journal. 91: 478-483. PMID 5840707 DOI: 10.1042/Bj0910478 |
0.653 |
|
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