| Year |
Citation |
Score |
| 2020 |
Anselmi M, Borbély A, Figueras E, Michalek C, Kemker I, Gentilucci L, Sewald N. Linker Hydrophilicity Modulates the Anticancer Activity of RGD-Cryptophycin Conjugates. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 32955139 DOI: 10.1002/Chem.202003471 |
0.307 |
|
| 2020 |
Zhao J, Santino F, Giacomini D, Gentilucci L. Integrin-Targeting Peptides for the Design of Functional Cell-Responsive Biomaterials. Biomedicines. 8. PMID 32854363 DOI: 10.3390/Biomedicines8090307 |
0.307 |
|
| 2020 |
Stefan A, Gentilucci L, Piaz FD, D'Alessio F, Santino F, Hochkoeppler A. Purification from Deinococcus radiodurans of a 66 kDa ABC transporter acting on peptides containing at least 3 amino acids. Biochemical and Biophysical Research Communications. 529: 869-875. PMID 32819591 DOI: 10.1016/J.Bbrc.2020.06.060 |
0.355 |
|
| 2020 |
Bedini A, Di Cesare Mannelli L, Micheli L, Baiula M, Vaca G, De Marco R, Gentilucci L, Ghelardini C, Spampinato S. Functional Selectivity and Antinociceptive Effects of a Novel KOPr Agonist. Frontiers in Pharmacology. 11: 188. PMID 32210803 DOI: 10.3389/Fphar.2020.00188 |
0.322 |
|
| 2020 |
Anselmi M, Stavole P, Boanini E, Bigi A, Juaristi E, Gentilucci L. Green synthesis of bioactive oligopeptides promoted by recyclable nanocrystalline hydroxyapatite. Future Medicinal Chemistry. PMID 32064939 DOI: 10.4155/Fmc-2019-0320 |
0.392 |
|
| 2019 |
Martelli G, Baiula M, Caligiana A, Galletti P, Gentilucci L, Artali R, Spampinato SM, Giacomini D. Could dissecting the molecular framework of β-lactam integrin ligands enhance selectivity? Journal of Medicinal Chemistry. PMID 31670514 DOI: 10.1021/Acs.Jmedchem.9B01000 |
0.36 |
|
| 2019 |
Baiula M, Spampinato S, Gentilucci L, Tolomelli A. Novel Ligands Targeting αβ Integrin: Therapeutic Applications and Perspectives. Frontiers in Chemistry. 7: 489. PMID 31338363 DOI: 10.3389/Fchem.2019.00489 |
0.602 |
|
| 2019 |
Wtorek K, Artali R, Piekielna-Ciesielska J, Koszuk J, Kluczyk A, Gentilucci L, Janecka A. Endomorphin-2 analogs containing modified tyrosines: Biological and theoretical investigation of the influence on conformation and pharmacological profile. European Journal of Medicinal Chemistry. 179: 527-536. PMID 31276897 DOI: 10.1016/J.Ejmech.2019.06.077 |
0.365 |
|
| 2019 |
De Marco R, Zhao J, Greco A, Ioannone S, Gentilucci L. In-peptide synthesis of imidazolidin-2-one scaffolds, equippable with proteinogenic or taggable/linkable side chains, general promoters of unusual secondary structures. The Journal of Organic Chemistry. PMID 30957502 DOI: 10.1021/Acs.Joc.8B03055 |
0.433 |
|
| 2018 |
Dattoli SD, Baiula M, De Marco R, Bedini A, Anselmi M, Gentilucci L, Spampinato S. DS-70, a novel and potent α integrin antagonist, is an effective treatment for experimental allergic conjunctivitis in guinea pigs. British Journal of Pharmacology. PMID 30051467 DOI: 10.1111/Bph.14458 |
0.34 |
|
| 2018 |
De Marco R, Bedini A, Spampinato SM, Comellini L, Zhao J, Artali R, Gentilucci L. Constraining endomorphin-1 by β,α-hybrid dipeptide/heterocycle scaffolds: identification of a novel κ-opioid receptor selective partial agonist. Journal of Medicinal Chemistry. PMID 29901392 DOI: 10.1021/Acs.Jmedchem.8B00296 |
0.411 |
|
| 2017 |
Marco R, Gentilucci L. Tryptophan-Containing Non-Cationizable Opioid Peptides - a new chemotype with unusual structure and in vivo activity. Future Medicinal Chemistry. PMID 29130348 DOI: 10.4155/Fmc-2017-0104 |
0.358 |
|
| 2017 |
Adamska-Bartłomiejczyk A, De Marco R, Gentilucci L, Kluczyk A, Janecka A. Design and characterization of opioid ligands based on cycle-in-macrocycle scaffold. Bioorganic & Medicinal Chemistry. PMID 28318893 DOI: 10.1016/J.Bmc.2017.02.057 |
0.376 |
|
| 2016 |
Gentilucci L, Tosi P, Bauer A, Marco R. Modern tools for the chemical ligation and synthesis of modified peptides and proteins. Future Medicinal Chemistry. PMID 27874285 DOI: 10.4155/Fmc-2016-0175 |
0.317 |
|
| 2016 |
De Marco R, Bedini A, Spampinato SM, Cavina L, Pirazzoli E, Gentilucci L. Versatile Picklocks to Access All Opioid Receptors: Tuning the Selectivity and Functional Profile of the Cyclotetrapeptide c[Phe-D-Pro-Phe-Trp] (CJ-15,208). Journal of Medicinal Chemistry. PMID 27607020 DOI: 10.1021/Acs.Jmedchem.6B00420 |
0.358 |
|
| 2016 |
Piekielna J, De Marco R, Gentilucci L, Cerlesi MC, Calo G, Tomböly C, Artali R, Janecka A. Redoubling the ring size of an endomorphin-2 analog transforms a centrally acting mu-opioid receptor agonist into a pure peripheral analgesic. Biopolymers. PMID 27038094 DOI: 10.1002/Bip.22846 |
0.337 |
|
| 2016 |
De Marco R, Tolomelli A, Juaristi E, Gentilucci L. Integrin Ligands with α/β-Hybrid Peptide Structure: Design, Bioactivity, and Conformational Aspects. Medicinal Research Reviews. PMID 26777675 DOI: 10.1002/Med.21383 |
0.681 |
|
| 2016 |
Marco RD, Mazzotti G, Greco A, Gentilucci L. Heterocyclic Scaffolds in the Design of Peptidomimetic Integrin Ligands: Synthetic Strategies, Structural Aspects, and Biological Activity. Current Topics in Medicinal Chemistry. 16: 343-59. PMID 26265351 DOI: 10.2174/1568026615666150812121614 |
0.33 |
|
| 2016 |
Gentilucci L, Gallo F, Meloni F, Mastandrea M, Del Secco B, De Marco R. Controlling Cyclopeptide Backbone Conformation with β/α-Hybrid Peptide-Heterocycle Scaffolds European Journal of Organic Chemistry. 2016: 3243-3251. DOI: 10.1002/Ejoc.201600448 |
0.443 |
|
| 2015 |
Perlikowska R, Piekielna J, Gentilucci L, De Marco R, Cerlesi MC, Calo G, Artali R, Tömböly C, Kluczyk A, Janecka A. Synthesis of mixed MOR/KOR efficacy cyclic opioid peptide analogs with antinociceptive activity after systemic administration. European Journal of Medicinal Chemistry. 109: 276-286. PMID 26785295 DOI: 10.1016/J.Ejmech.2015.12.012 |
0.341 |
|
| 2015 |
De Marco R, Mazzotti G, Dattoli SD, Baiula M, Spampinato S, Greco A, Gentilucci L. 5-aminomethyloxazolidine-2,4-dione hybrid α/β-dipeptide scaffolds as inductors of constrained conformations: Applications to the synthesis of integrin antagonists. Biopolymers. 104: 636-49. PMID 26211418 DOI: 10.1002/Bip.22704 |
0.417 |
|
| 2015 |
Tolomelli A, Baiula M, Viola A, Ferrazzano L, Gentilucci L, Dattoli SD, Spampinato S, Juaristi E, Escudero M. Dehydro-β-proline Containing α4β1 Integrin Antagonists: Stereochemical Recognition in Ligand-Receptor Interplay. Acs Medicinal Chemistry Letters. 6: 701-6. PMID 26101577 DOI: 10.1021/Acsmedchemlett.5B00125 |
0.661 |
|
| 2015 |
Piekielna J, Kluczyk A, Gentilucci L, Cerlesi MC, Calo' G, Tomböly C, Łapiński K, Janecki T, Janecka A. Ring size in cyclic endomorphin-2 analogs modulates receptor binding affinity and selectivity. Organic & Biomolecular Chemistry. 13: 6039-46. PMID 25948019 DOI: 10.1039/C5Ob00565E |
0.392 |
|
| 2015 |
Tolomelli A, Baiula M, Viola A, Ferrazzano L, Gentilucci L, Dattoli SD, Spampinato S, Juaristi E, Escudero M. Dehydro-β-proline Containing α4β1 Integrin Antagonists: Stereochemical Recognition in Ligand-Receptor Interplay Acs Medicinal Chemistry Letters. 6: 701-706. DOI: 10.1021/acsmedchemlett.5b00125 |
0.594 |
|
| 2014 |
Janecka A, Gentilucci L. Cyclic endomorphin analogs in targeting opioid receptors to achieve pain relief. Future Medicinal Chemistry. 6: 2093-101. PMID 25531970 DOI: 10.4155/Fmc.14.132 |
0.3 |
|
| 2014 |
Piekielna J, Gentilucci L, De Marco R, Perlikowska R, Adamska A, Olczak J, Mazur M, Artali R, Modranka J, Janecki T, Tömböly C, Janecka A. Cyclic side-chain-linked opioid analogs utilizing cis- and trans-4-aminocyclohexyl-D-alanine. Bioorganic & Medicinal Chemistry. 22: 6445-51. PMID 25456075 DOI: 10.1016/J.Bmc.2014.10.022 |
0.38 |
|
| 2014 |
De Marco R, Cavina L, Greco A, Gentilucci L. Easy preparation of dehydroalanine building blocks equipped with oxazolidin-2-one chiral auxiliaries, and applications to the stereoselective synthesis of substituted tryptophans. Amino Acids. 46: 2823-39. PMID 25261130 DOI: 10.1007/S00726-014-1839-3 |
0.489 |
|
| 2014 |
Greco A, Tani S, De Marco R, Gentilucci L. Synthesis and analysis of the conformational preferences of 5-aminomethyloxazolidine-2,4-dione scaffolds: first examples of β(2)- and β(2, 2)-homo-Freidinger lactam analogues. Chemistry (Weinheim An Der Bergstrasse, Germany). 20: 13390-404. PMID 25182659 DOI: 10.1002/Chem.201402519 |
0.46 |
|
| 2014 |
De Marco R, Bedini A, Spampinato S, Gentilucci L. Synthesis of tripeptides containing D-Trp substituted at the indole ring, assessment of opioid receptor binding and in vivo central antinociception. Journal of Medicinal Chemistry. 57: 6861-6. PMID 25051243 DOI: 10.1021/Jm5002925 |
0.347 |
|
| 2014 |
Galletti P, Soldati R, Pori M, Durso M, Tolomelli A, Gentilucci L, Dattoli SD, Baiula M, Spampinato S, Giacomini D. Targeting integrins αvβ3 and α5β1 with new β-lactam derivatives European Journal of Medicinal Chemistry. 83: 284-293. PMID 24973662 DOI: 10.1016/J.Ejmech.2014.06.041 |
0.642 |
|
| 2014 |
Dattoli SD, De Marco R, Baiula M, Spampinato S, Greco A, Tolomelli A, Gentilucci L. Synthesis and assay of retro-α4β1 integrin-targeting motifs. European Journal of Medicinal Chemistry. 73: 225-32. PMID 24412498 DOI: 10.1016/J.Ejmech.2013.12.009 |
0.63 |
|
| 2014 |
Viola A, Ferrazzano L, Martelli G, Ancona S, Gentilucci L, Tolomelli A. An improved microwave assisted protocol for Yonemitsu-type trimolecular condensation Tetrahedron. 6781-6788. DOI: 10.1016/J.Tet.2014.07.062 |
0.661 |
|
| 2014 |
Greco A, De Marco R, Tani S, Giacomini D, Galletti P, Tolomelli A, Juaristi E, Gentilucci L. Convenient synthesis of the antibiotic linezolid via an oxazolidine-2,4-dione intermediate derived from the chiral building block isoserine European Journal of Organic Chemistry. 2014: 7614-7620. DOI: 10.1002/Ejoc.201402888 |
0.691 |
|
| 2013 |
Tolomelli A, Baiula M, Belvisi L, Viola A, Gentilucci L, Troisi S, Dattoli SD, Spampinato S, Civera M, Juaristi E, Escudero M. Modulation of αvβ₃- and α₅βâ‚-integrin-mediated adhesion by dehydro-β-amino acids containing peptidomimetics. European Journal of Medicinal Chemistry. 66: 258-68. PMID 23811088 DOI: 10.1016/J.Ejmech.2013.05.050 |
0.673 |
|
| 2013 |
De Marco R, Greco A, Rupiani S, Tolomelli A, Tomasini C, Pieraccini S, Gentilucci L. In-peptide synthesis of di-oxazolidinone and dehydroamino acid-oxazolidinone motifs as β-turn inducers. Organic & Biomolecular Chemistry. 11: 4316-26. PMID 23673614 DOI: 10.1039/C3Ob40357B |
0.798 |
|
| 2013 |
De Marco R, Tolomelli A, Greco A, Gentilucci L. Controlled solid phase peptide bond formation using N-carboxyanhydrides and PEG resins in water Acs Sustainable Chemistry and Engineering. 1: 566-569. DOI: 10.1021/Sc400058R |
0.625 |
|
| 2012 |
De Marco R, Tolomelli A, Spampinato S, Bedini A, Gentilucci L. Opioid activity profiles of oversimplified peptides lacking in the protonable N-terminus Journal of Medicinal Chemistry. 55: 10292-10296. PMID 22995061 DOI: 10.1021/Jm301213S |
0.623 |
|
| 2012 |
Gentilucci L, Tolomelli A, De Marco R, Artali R. Molecular docking of opiates and opioid peptides, a tool for the design of selective agonists and antagonists, and for the investigation of atypical ligand-receptor interactions Current Medicinal Chemistry. 19: 1587-1601. PMID 22376035 DOI: 10.2174/092986712799945030 |
0.611 |
|
| 2012 |
De Marco R, Tolomelli A, Campitiello M, Rubini P, Gentilucci L. Expedient synthesis of pseudo-Pro-containing peptides: Towards constrained peptidomimetics and foldamers Organic and Biomolecular Chemistry. 10: 2307-2317. PMID 22318404 DOI: 10.1039/C2Ob07172J |
0.646 |
|
| 2012 |
Tolomelli A, Cardillo G, Gentilucci L, Juris R, Viola A, Juaristi E. Exploring the reactivity of alkylidene malonamides: Synthesis of polyfunctionalized isoxazolidinones, aziridines and oxazolines Arkivoc. 2012: 196-209. DOI: 10.3998/Ark.5550190.0013.518 |
0.757 |
|
| 2012 |
Castellucci N, Gentilucci L, Tomasini C. One-pot synthesis of poly-substituted tetramic acids for the preparation of putative turn mimics Tetrahedron. 68: 4506-4512. DOI: 10.1016/J.Tet.2011.11.006 |
0.465 |
|
| 2011 |
Tolomelli A, Gentilucci L, Mosconi E, Viola A, Dattoli SD, Baiula M, Spampinato S, Belvisi L, Civera M. Development of Isoxazoline-Containing Peptidomimetics as Dual α vβ 3 and α 5β 1 Integrin Ligands Chemmedchem. 6: 2264-2272. PMID 21953988 DOI: 10.1002/Cmdc.201100372 |
0.67 |
|
| 2011 |
Gentilucci L, Tolomelli A, de Marco R, Spampinato S, Bedini A, Artali R. The inverse type II β-Turn on D-Trp-Phe, a Pharmacophoric Motif for MOR Agonists Chemmedchem. 6: 1640-1653. PMID 21721130 DOI: 10.1002/Cmdc.201100169 |
0.617 |
|
| 2011 |
Tolomelli A, Gentilucci L, Mosconi E, Viola A, Paradisi E. A straightforward route to enantiopure 2-substituted-3,4-dehydro-β- proline via ring closing metathesis Amino Acids. 41: 575-586. PMID 21541679 DOI: 10.1007/S00726-011-0921-3 |
0.705 |
|
| 2011 |
De Marco R, Gentilucci L, Tolomelli A, Feddersen S, Spampinato S, Bedini A, Artali R. Design and synthesis of opioid peptide analogues and mimetics Pharmacological Reports. 63: 226. DOI: 10.1016/S1734-1140(11)70444-3 |
0.663 |
|
| 2011 |
Gentilucci L, De Marco R, Tolomelli A, Feddersen S, Spampinato S, Bedini A, Artali R. A novel family of minimalist opioid peptides deprived of the classic pharmacophores Pharmacological Reports. 63: 212. DOI: 10.1016/S1734-1140(11)70426-1 |
0.601 |
|
| 2011 |
Gentilucci L, Tolomelli A, De Marco R, Tomasini C, Feddersen S. Synthesis of constrained peptidomimetics containing 2-oxo-1,3-oxazolidine- 4-carboxylic acids European Journal of Organic Chemistry. 4925-4930. DOI: 10.1002/Ejoc.201100346 |
0.659 |
|
| 2010 |
Bedini A, Baiula M, Gentilucci L, Tolomelli A, De Marco R, Spampinato S. Peripheral antinociceptive effects of the cyclic endomorphin-1 analog c[YpwFG] in a mouse visceral pain model Peptides. 31: 2135-2140. PMID 20713109 DOI: 10.1016/J.Peptides.2010.08.005 |
0.59 |
|
| 2010 |
Gentilucci L, de Marco R, Cerisoli L. Chemical modifications designed to improve peptide stability: Incorporation of non-natural amino acids, pseudo-peptide bonds, and cyclization Current Pharmaceutical Design. 16: 3185-3203. PMID 20687878 DOI: 10.2174/138161210793292555 |
0.351 |
|
| 2010 |
Gentilucci L, Cardillo G, Spampinato S, Tolomelli A, Squassabia F, De Marco R, Bedini A, Baiula M, Belvisi L, Civera M. Antiangiogenic effect of dual/selective α5 β1/αvβ3 integrin antagonists designed on partially modified retro-inverso cyclotetrapeptide mimetics Journal of Medicinal Chemistry. 53: 106-118. PMID 20055426 DOI: 10.1021/Jm9013532 |
0.679 |
|
| 2010 |
Gentilucci L, Cerisoli L, Marco RD, Tolomelli A. A simple route towards peptide analogues containing substituted (S)- or (R)-tryptophans Tetrahedron Letters. 51: 2576-2579. DOI: 10.1016/J.Tetlet.2010.03.017 |
0.673 |
|
| 2010 |
Cardillo G, Gennari A, Gentilucci L, Mosconi E, Tolomelli A, Troisi S. Synthesis of chiral non-racemic intermediates and Arg-Gly-Asp mimetics by CaLB-catalyzed resolution Tetrahedron Asymmetry. 21: 96-102. DOI: 10.1016/J.Tetasy.2009.12.021 |
0.78 |
|
| 2010 |
Cardillo G, Gentilucci L, Mosconi E, Tolomelli A, Troisi S, Juaristi E. Highly regio- and stereoselective palladium-catalyzed allylic carbonate amination. A practical route to dehydro-β-amino esters Tetrahedron. 66: 4994-4999. DOI: 10.1016/J.Tet.2010.05.022 |
0.758 |
|
| 2010 |
CARDILLO G, GENTILUCCI L, BASTARDAS IR, TOLOMELLI A. ChemInform Abstract: Diastereoselective Synthesis of 3′-Unsubstituted N-Boc-Aziridine from a Readily Available Chiral α,β-Unsaturated Imide. Cheminform. 29: no-no. DOI: 10.1002/chin.199845125 |
0.654 |
|
| 2010 |
CARDILLO G, GENTILUCCI L, TOLOMELLI A, TOMASINI C. ChemInform Abstract: Formation of Aziridine-2-amides Through 5-Halo-6-methylperhydropyrimidin-4-ones. A Route to Enantiopure L- and D-Threonine and allo-Threonine. Cheminform. 29: no-no. DOI: 10.1002/chin.199838231 |
0.552 |
|
| 2010 |
GENTILUCCI L, GRIJZEN Y, THIJS L, ZWANENBURG B. ChemInform Abstract: Convenient Synthesis of Optically Active 2H-Azirine-2-carboxylic Esters by Swern Oxidation of Aziridine-2-carboxylic Esters. Cheminform. 26: no-no. DOI: 10.1002/chin.199540126 |
0.433 |
|
| 2009 |
Gentilucci L, Cardillo G, Tolomelli A, Squassabia F, De Marco R, Chiriano G. Cyclopeptide analogs for generating new molecular and 3D diversity Combinatorial Chemistry and High Throughput Screening. 12: 929-939. PMID 20025560 DOI: 10.2174/138620709789824754 |
0.717 |
|
| 2009 |
Gentilucci L, Cardillo G, Tolomelli A, De Marco R, Garelli A, Spampinato S, Spartà A, Juaristi E. Synthesis and conformational analysis of cyclotetrapeptide mimetic beta-turn templates and validation as 3D scaffolds. Chemmedchem. 4: 517-23. PMID 19226499 DOI: 10.1002/Cmdc.200800407 |
0.705 |
|
| 2009 |
Benfatti F, Cardillo G, Contaldi S, Gentilucci L, Mosconi E, Tolomelli A, Juaristi E, Reyes-Rangel G. A convenient synthesis of functionalized isoxazolines and related 5-hydroxyisoxazolidine-4-carboxylates Tetrahedron. 65: 2478-2483. DOI: 10.1016/J.Tet.2009.01.071 |
0.734 |
|
| 2009 |
Cardillo G, Gennari A, Gentilucci L, Mosconi E, Tolomelli A, Troisi S. Dehydro-β-amino acid containing peptides as promising sequences for drug development European Journal of Organic Chemistry. 5991-5997. DOI: 10.1002/Ejoc.200900870 |
0.773 |
|
| 2009 |
Cardillo G, Gentilucci L, Tolomelli A. Asymmetric Synthesis of Three- and Four-Membered Ring Heterocycles Asymmetric Synthesis of Nitrogen Heterocycles. 1-50. DOI: 10.1002/9783527625505.ch1 |
0.7 |
|
| 2008 |
Benfatti F, Cardillo G, Gentilucci L, Mosconi E, Tolomelli A. Synthesis of dehydro-β-amino esters via highly regioselective amination of allylic carbonates Organic Letters. 10: 2425-2428. PMID 18484731 DOI: 10.1021/Ol8006919 |
0.753 |
|
| 2008 |
Gentilucci L, Squassabia F, Demarco R, Artali R, Cardillo G, Tolomelli A, Spampinato S, Bedini A. Investigation of the interaction between the atypical agonist c[YpwFG] and MOR Febs Journal. 275: 2315-2337. PMID 18397320 DOI: 10.1111/J.1742-4658.2008.06386.X |
0.694 |
|
| 2008 |
Benfatti F, Cardillo G, Gentilucci L, Mosconi E, Tolomelli A. Lewis acid induced highly regioselective synthesis of a new class of substituted isoxazolidines Synlett. 2605-2608. DOI: 10.1055/S-0028-1083520 |
0.746 |
|
| 2008 |
Benfatti F, Bottoni A, Cardillo G, Gentilucci L, Monari M, Mosconi E, Stenta M, Tolomelli A. Synthesis of ethyl 5-hydroxyisoxazolidine-4-carboxylates via michael addition/intramolecular hemiketalisation European Journal of Organic Chemistry. 6119-6127. DOI: 10.1002/Ejoc.200800719 |
0.72 |
|
| 2008 |
Gentilucci L, Cardillo G, Tolomelli A, Spampinato S, Sparta A, Squassabia F. Cyclotetrapeptide mimics based on a 13-membered, partially modified retro-inverso structure European Journal of Organic Chemistry. 729-735. DOI: 10.1002/Ejoc.200700932 |
0.755 |
|
| 2008 |
Benfatti F, Bottoni A, Cardillo G, Fabbroni S, Gentilucci L, Stenta M, Tolomelli A. The cycloaddition reaction between α-bromo vinylketenes and imines: A combined experimental and theoretical study Advanced Synthesis and Catalysis. 350: 2261-2273. DOI: 10.1002/Adsc.200800348 |
0.734 |
|
| 2007 |
Benfatti F, Cardillo G, Fabbroni S, Galzerano P, Gentilucci L, Juris R, Tolomelli A, Baiula M, Spartà A, Spampinato S. Synthesis and biological evaluation of non-peptide αvβ3/α5β1 integrin dual antagonists containing 5,6-dihydropyridin-2-one scaffolds Bioorganic and Medicinal Chemistry. 15: 7380-7390. PMID 17869121 DOI: 10.1016/J.Bmc.2007.07.049 |
0.732 |
|
| 2007 |
Gentilucci L, Cardillo G, Squassabia F, Tolomelli A, Spampinato S, Sparta A, Baiula M. Inhibition of cancer cell adhesion by heterochiral Pro-containing RGD mimetics Bioorganic and Medicinal Chemistry Letters. 17: 2329-2333. PMID 17289386 DOI: 10.1016/J.Bmcl.2007.01.073 |
0.699 |
|
| 2007 |
Benfatti F, Cardillo G, Gentilucci L, Tolomelli A. Synthesis and biological evaluation of unprecedented classes of spiro-β-lactams and azido-β-lactams as acyl-CoA:cholesterol acyltransferase inhibitors Bioorganic and Medicinal Chemistry Letters. 17: 1946-1950. PMID 17275297 DOI: 10.1016/J.Bmcl.2007.01.027 |
0.723 |
|
| 2007 |
Gentilucci L, Tolomelli A, Squassabia F. Topological exploration of cyclic endomorphin-1 analogues, structurally defined models for investigating the bioactive conformation of MOR agonists Protein and Peptide Letters. 14: 51-56. PMID 17266651 DOI: 10.2174/092986607779117218 |
0.624 |
|
| 2007 |
Gentilucci L, Squassabia F, Artali R. Re-discussion of the importance of ionic interactions in stabilizing ligand-opioid receptor complex and in activating signal transduction Current Drug Targets. 8: 185-196. PMID 17266541 DOI: 10.2174/138945007779315704 |
0.303 |
|
| 2007 |
Benfatti F, Cardillo G, Gentilucci L, Mosconi E, Tolomelli A. Enzymatic resolution of ethyl 3-hydroxy-2(1′substituted-methylidene)-butyrate by Pseudomonas cepacia lipase catalyzed acetylation Tetrahedron Asymmetry. 18: 2227-2232. DOI: 10.1016/J.Tetasy.2007.09.002 |
0.72 |
|
| 2007 |
Benfatti F, Cardillo G, Gentilucci L, Tolomelli A. Synthesis of four-membered ring spiro-β-lactams by epoxide ring-opening European Journal of Organic Chemistry. 3199-3205. DOI: 10.1002/Ejoc.200601110 |
0.75 |
|
| 2007 |
Benfatti F, Cardillo G, Gentilucci L, Tolomelli A, Monari M, Piccinelli F. A microwave-enhanced, lewis acid-catalyzed synthesis of 1,3-dioxolanes and oxazolines from epoxides Advanced Synthesis and Catalysis. 349: 1256-1264. DOI: 10.1002/Adsc.200600516 |
0.75 |
|
| 2006 |
Benfatti F, Cardillo G, Gentilucci L, Perciaccante R, Tolomelli A, Catapano A. Synthesis and biological evaluation of azido- and aziridino-hydroxyl- β-lactams through stereo- and regioselective epoxide ring opening Journal of Organic Chemistry. 71: 9229-9232. PMID 17109554 DOI: 10.1021/Jo0615652 |
0.748 |
|
| 2006 |
Gentilucci L, Tolomelli A, Squassabia F. Peptides and peptidomimetics in medicine, surgery and biotechnology Current Medicinal Chemistry. 13: 2449-2466. PMID 16918365 DOI: 10.2174/092986706777935041 |
0.612 |
|
| 2006 |
Gentilucci L, Cardillo G, Tolomelli A, Squassabia F, Tiozzo C. A novel family of minimal PMRI cyclic peptides as versatile scaffolds for generating new molecular topology Medicinal Chemistry. 2: 395-400. PMID 16848752 DOI: 10.2174/157340606777724077 |
0.715 |
|
| 2006 |
Cardillo G, Gentilucci L, Tolomelli A. Unusual amino acids: Synthesis and introduction into naturally occurring peptides and biologically active analogues Mini-Reviews in Medicinal Chemistry. 6: 293-304. PMID 16515468 DOI: 10.2174/138955706776073394 |
0.731 |
|
| 2006 |
Benfatti F, Cardillo G, Fabbroni S, Gentilucci L, Perciaccante R, Tolomelli A, Baiula M, Spampinato S. Synthesis of enantiomerically pure αvβ3 integrin ligands based on a 5,6-dihydropyridin-2-one scaffold Tetrahedron Asymmetry. 17: 167-170. DOI: 10.1016/J.Tetasy.2005.12.006 |
0.745 |
|
| 2005 |
Cardillo G, Fabbroni S, Gentilucci L, Perciaccante R, Piccinelli F, Tolomelli A. Highly diastereoselective allylic azide formation and isomerization. Synthesis of 3(2′-amino)-β-lactams Organic Letters. 7: 533-536. PMID 15704887 DOI: 10.1021/Ol047815N |
0.765 |
|
| 2005 |
Benfatti F, Cardillo G, Fabbroni S, Gentilucci L, Perciaccante R, Tolomelli A. Introduction of hydroxyl- or keto- functionalities in azetidin-2-ones side chain via allylic bromide rearrangement, followed by supported reagent substitution Arkivoc. 2005. DOI: 10.3998/Ark.5550190.0006.611 |
0.63 |
|
| 2005 |
Benfatti F, Cardillo G, Gentilucci L, Perciaccante R, Tolomelli A. An investigation of the reactivity of MCPBA and α-bromoalkenes under traditional or microwave-assisted conditions: Selective formation of epoxides or allylic bromides Synlett. 2204-2208. DOI: 10.1055/S-2005-872254 |
0.733 |
|
| 2005 |
Benfatti F, Cardillo G, Fabbroni S, Gentilucci L, Perciaccante R, Piccinelli F, Tolomelli A. Zinc metal-promoted nucleophilic addition of azetidin-2-ones to aldehydes and nitriles Synthesis. 61-70. DOI: 10.1055/S-2004-834897 |
0.723 |
|
| 2005 |
Cardillo G, Fabbroni S, Gentilucci L, Perciaccante R, Tolomelli A. Highly regio- and diastereoselective palladium-catalyzed allylic substitution. Synthesis of 3-(2-aminobutylidene)-4-arylazetidin-2-ones Advanced Synthesis and Catalysis. 347: 833-838. DOI: 10.1002/Adsc.200404385 |
0.76 |
|
| 2005 |
Benfatti F, Cardillo G, Fabbroni S, Gentilucci L, Perciaccante R, Tolomelli A. Introduction of hydroxyl- or keto- functionalities into the side chain of azetidin-2-ones via allylic bromide rearrangement, followed by supported reagent substitution Arkivoc. 2005: 136-152. |
0.518 |
|
| 2004 |
Cardillo G, Gentilucci L, Tolomelli A, Spinosa R, Calienni M, Qasem AR, Spampinato S. Synthesis and evaluation of the affinity toward μ-opioid receptors of atypical, lipophilic ligands based on the sequence c[-Tyr-Pro-Trp-Phe-Gly-] Journal of Medicinal Chemistry. 47: 5198-5203. PMID 15456262 DOI: 10.1021/Jm0498811 |
0.712 |
|
| 2004 |
Gentilucci L, Tolomelli A. Recent advances in the investigation of the bioactive conformation of peptides active at the μ-opioid receptor. Conformational analysis of endomorphins Current Topics in Medicinal Chemistry. 4: 105-121. PMID 14754379 DOI: 10.2174/1568026043451627 |
0.63 |
|
| 2004 |
Gentilucci L. New trends in the development of opioid peptide analogues as advanced remedies for pain relief Current Topics in Medicinal Chemistry. 4: 19-38. PMID 14754374 DOI: 10.2174/1568026043451663 |
0.35 |
|
| 2004 |
Cardillo G, Fabbroni S, Gentilucci L, Perciaccante R, Piccinelli F, Tolomelli A. Practical synthesis of 3-bromo-5,6-dihydropyridin-2-ones via $beta;,$gamma;-unsaturated $alpha;-bromo-ketene/imine cycloaddition*1, *2 Tetrahedron. 60: 5031-5040. DOI: 10.1016/S0040-4020(04)00552-6 |
0.688 |
|
| 2004 |
Cardillo G, Fabbroni S, Gentilucci L, Perciaccante R, Tolomelli A. α-Bromo-β,γ-unsaturated ketenes for the synthesis of α-benzylamino-β,γ-unsaturated acids Tetrahedron Asymmetry. 15: 593-601. DOI: 10.1016/J.Tetasy.2003.12.029 |
0.74 |
|
| 2004 |
Cardillo G, Fabbroni S, Gentilucci L, Perciaccante R, Piccinelli F, Tolomelli A. Practical synthesis of 3-bromo-5,6-dihydropyridin-2-ones via β,γ-unsaturated α-bromo-ketene/imine cycloaddition Tetrahedron. 60: 5031-5040. DOI: 10.1016/J.Tet.2004.04.021 |
0.763 |
|
| 2003 |
Cardillo G, Gentilucci L, Tolomelli A, Qasem AR, Spampinato S, Calienni M. Conformational analysis and μ-opioid receptor affinity of short peptides, endomorphin models in a low polarity solvent Organic and Biomolecular Chemistry. 1: 3010-3014. PMID 14518122 DOI: 10.1039/B306161M |
0.701 |
|
| 2003 |
Cardillo G, Gentilucci L, Tolomelli A, Calienni M, Qasem AR, Spampinato S. Stability against enzymatic hydrolysis of endomorphin-1 analogues containing beta-proline. Organic & Biomolecular Chemistry. 1: 1498-502. PMID 12926278 DOI: 10.1039/B301507F |
0.708 |
|
| 2003 |
Spampinato S, Qasem AR, Calienni M, Murari G, Gentilucci L, Tolomelli A, Cardillo G. Antinociception by a peripherally administered novel endomorphin-1 analogue containing β-proline European Journal of Pharmacology. 469: 89-95. PMID 12782189 DOI: 10.1016/S0014-2999(03)01736-9 |
0.693 |
|
| 2003 |
Cardillo G, Fabbroni S, Gentilucci L, Gianotti M, Tolomeklli A. A straightforward method for the synthesis of alkylidene and arylidene malonates through proline-catalyzed Knoevenagel condensation Synthetic Communications. 33: 1587-1594. DOI: 10.1081/Scc-120018782 |
0.594 |
|
| 2003 |
Cardillo G, Gentilucci L, Tolomelli A, Calienni M, Qasem AR, Spampinato S. Stability against enzymatic hydrolysis of endomorphin-1 analogues containing β-proline Organic and Biomolecular Chemistry. 1: 1498-1502. DOI: 10.1039/b301507f |
0.688 |
|
| 2003 |
Cardillo G, Gentilucci L, Tolomelli A. Aziridines and Oxazolines: Valuable Intermediates in the Synthesis of Unusual Amino Acids Aldrichimica Acta. 36: 39-50. |
0.564 |
|
| 2002 |
Cardillo G, Gentilucci L, de Matteis V. Lewis acid-promoted synthesis and reactivity of β-O-benzylhydroxylamino imides derived from D-glyceraldehyde Journal of Organic Chemistry. 67: 5957-5962. PMID 12182628 DOI: 10.1021/Jo0259055 |
0.615 |
|
| 2002 |
Cardillo G, Gentilucci L, Qasem AR, Sgarzi F, Spampinato S. Endomorphin-1 analogues containing β-proline are μ-opioid receptor agonists and display enhanced enzymatic hydrolysis resistance Journal of Medicinal Chemistry. 45: 2571-2578. PMID 12036366 DOI: 10.1021/Jm011059Z |
0.575 |
|
| 2002 |
Cardillo G, Fabbroni S, Gentilucci L, Gianotti M, Perciaccante R, Selva S, Tolomelli A. Enantioselective synthesis of aziridine 2,2-dicarboxylates. Part II: Determination of the absolute configuration Tetrahedron Asymmetry. 13: 1411-1415. DOI: 10.1016/S0957-4166(02)00341-5 |
0.742 |
|
| 2002 |
Cardillo G, Fabbroni S, Gentilucci L, Gianotti M, Percacciante R, Tolomelli A. Enantioselective synthesis of aziridine 2,2-dicarboxylates. Part I: Copper(II)-bisoxazoline complex-catalysed Michael reaction on alkylidene malonates Tetrahedron Asymmetry. 13: 1407-1410. DOI: 10.1016/S0957-4166(02)00340-3 |
0.751 |
|
| 2001 |
Cardillo G, Gentilucci L, Gianotti M, Perciaccante R, Tolomelli A. Synthesis of aziridine-2,2-dicarboxylates via 1,4-addition of N,O-(bistrimethylsilyl)hydroxylamine to α,β-unsaturated malonates Journal of Organic Chemistry. 66: 8657-8660. PMID 11735554 DOI: 10.1021/Jo015907+ |
0.731 |
|
| 2001 |
Cardillo G, Gentilucci L, Gianotti M, Tolomelli A. NMR investigations on boron complexes in the conjugate addition on α,β-unsaturated imides Organic Letters. 3: 1165-1167. PMID 11348185 DOI: 10.1021/Ol015616N |
0.725 |
|
| 2001 |
Cardillo G, Gentilucci L, Gianotti M, Kim H, Perciaccante R, Tolomelli A. Conjugate addition of hydroxylamino derivatives to alkylidene malonates in the presence of chiral Lewis acids Tetrahedron Asymmetry. 12: 2395-2398. DOI: 10.1016/S0957-4166(01)00427-X |
0.753 |
|
| 2001 |
Cardillo G, Gentilucci L, Gianotti M, Tolomelli A. Asymmetric synthesis of 5-isopropyl-oxazoline-4-imide as syn-hydroxyleucine precursor Tetrahedron Asymmetry. 12: 563-569. DOI: 10.1016/S0957-4166(01)00084-2 |
0.751 |
|
| 2001 |
Cardillo G, Gentilucci L, Gianotti M, Tolomelli A. Microwave-assisted ring expansion of N-acetyl 3′-unsubstituted aziridine in the presence of Lewis acids Tetrahedron. 57: 2807-2812. DOI: 10.1016/S0040-4020(01)00123-5 |
0.738 |
|
| 2001 |
Cardillo G, Gentilucci L, Mohr GP. The ring expansions of glyceraldehyde-derived aziridine-2-carboxylates to oxazolines take place with an uncommon regiochemistry European Journal of Organic Chemistry. 3545-3551. DOI: 10.1002/1099-0690(200109)2001:18<3545::Aid-Ejoc3545>3.0.Co;2-K |
0.624 |
|
| 2000 |
Cardillo G, Gentilucci L, Melchiorre P, Spampinato S. Synthesis and binding activity of endomorphin-1 analogues containing beta-amino acids. Bioorganic & Medicinal Chemistry Letters. 10: 2755-8. PMID 11133084 DOI: 10.1016/S0960-894X(00)00562-X |
0.585 |
|
| 2000 |
Armaroli S, Cardillo G, Gentilucci L, Gianotti M, Tolomelli A. A new selective synthesis of the lle-allo-Thr-Gly tripeptide fragment of lysobactin Organic Letters. 2: 1105-1107. PMID 10804565 DOI: 10.1021/Ol005659O |
0.742 |
|
| 2000 |
Cardillo G, Gentilucci L, Gianotti M, Tolomelli A. Influence of lewis acids on the regioselectivity of N-Boc-aziridine-2-carboxylate microwave-assisted rearrangement Synlett. 1309-1311. DOI: 10.1055/S-2000-7125 |
0.716 |
|
| 2000 |
Cardillo G, Gentilucci L, Gianotti M, Tolomelli A. ChemInform Abstract: Influence of Lewis Acids on the Regioselectivity of N-Boc-aziridine-2-carboxylate Microwave-Assisted Rearrangement. Cheminform. 31: no-no. DOI: 10.1002/chin.200049126 |
0.613 |
|
| 2000 |
Cardillo G, Gentilucci L, Gianotti M, Tolomelli A. Synthesis of the phenylserine - leucine dipeptide fragment present in the antibiotic lysobactin from an aziridine-2-imide precursor European Journal of Organic Chemistry. 2489-2494. DOI: 10.1002/1099-0690(200007)2000:13<2489::Aid-Ejoc2489>3.0.Co;2-7 |
0.728 |
|
| 1999 |
Cardillo G, Gentilucci L, Tolomelli A, Tomasini C. A practical method for the synthesis of β-amino α-hydroxy acids. Synthesis of enantiomerically pure hydroxyaspartic acid and isoserine Synlett. 1727-1730. DOI: 10.1055/S-1999-2927 |
0.75 |
|
| 1999 |
Cardillo G, Gentilucci L, Tolomelli A. Synthesis of optically pure threonine-containing dipeptides by regio- and stereo-controlled ring expansion of aziridine-2-imide derivatives Chemical Communications. 167-168. DOI: 10.1039/A807063F |
0.736 |
|
| 1999 |
Cardillo G, Gentilucci L, Tolomelli A. Asymmetric synthesis of syn hydroxyphenylalanine via aziridine ring expansion to an oxazoline Tetrahedron Letters. 40: 8261-8264. DOI: 10.1016/S0040-4039(99)01734-7 |
0.713 |
|
| 1999 |
Cardillo G, Gentilucci L, Tolomelli A. Dipeptides containing D-serine or D-isoserine from the same (R)-aziridine-2-imide by a simple reversal of the synthetic procedure Tetrahedron. 55: 15151-15158. DOI: 10.1016/S0040-4020(99)00989-8 |
0.696 |
|
| 1999 |
Cardillo G, Gentilucci L, Tolomelli A, Tomasini C. Asymmetric 1,4 addition of Grignard reagents to chiral α,β- unsaturated esters in the presence of Lewis acids Tetrahedron. 55: 6231-6242. DOI: 10.1016/S0040-4020(99)00267-7 |
0.77 |
|
| 1998 |
Cardillo G, Gentilucci L, Tolomelli A, Tomasini C. A stereoselective synthesis of (2R,3S)-N-benzoylphenylisoserine methyl ester Journal of Organic Chemistry. 63: 2351-2353. DOI: 10.1021/Jo9714066 |
0.704 |
|
| 1998 |
Cardillo G, Gentilucci L, Tolomelli A, Tomasini C. Formation of Aziridine-2-amides through 5-Halo-6-methylperhydropyrimidin-4-ones. A Route to Enantiopurel- andd-Threonine andallo-Threonine The Journal of Organic Chemistry. 63: 3458-3462. DOI: 10.1021/Jo971388S |
0.622 |
|
| 1998 |
Cardillo G, Gentilucci L, Bastardas IR, Tolomelli A. Diastereoselective synthesis of 3'-unsubstituted N-BOC- Aziridine from a readily available chiral α-β-unsaturated imide Tetrahedron. 54: 8217-8222. DOI: 10.1016/S0040-4020(98)00459-1 |
0.75 |
|
| 1997 |
Bongini A, Cardillo G, Gentilucci L, Tomasini C. Synthesis of Enantiomerically Pure Aziridine-2-imides by Cyclization of Chiral 3′-Benzyloxyamino Imide Enolates Journal of Organic Chemistry. 62: 9148-9153. DOI: 10.1021/Jo971254E |
0.668 |
|
| 1997 |
Cardillo G, Gentilucci L, Tolomelli A, Tomasini C. Ring expansion of N-acetyl aziridine-2-imides to oxazoline-4-imides, useful precursors of pure β-hydroxy α-aminoacids Tetrahedron Letters. 38: 6953-6956. DOI: 10.1016/S0040-4039(97)01630-4 |
0.752 |
|
| 1996 |
Cardillo G, Gentilucci L, Tomasini C, Castejon-Bordas MPV. Synthesis of enantiomerically pure trans aziridine-2-carboxylates by diastereoselective Gabriel-Cromwell reaction Tetrahedron Asymmetry. 7: 755-762. DOI: 10.1016/0957-4166(96)00071-7 |
0.663 |
|
| 1996 |
Cardillo G, Casolari S, Gentilucci L, Tomasini C. Asymmetric Synthesis of AIkyl Aziridine-2-Carboxylates from Chiral 3'-Benzyloxy-aminoimides Angewandte Chemie (International Edition in English). 35: 1848-1849. DOI: 10.1002/Anie.199618481 |
0.609 |
|
| 1995 |
Cardillo G, Di Martino E, Gentilucci L, Tomasini C, Tomasoni L. Conjugate addition of chloride to α,β-unsaturated chiral imides promoted by BCl3-derivatives. Part II Tetrahedron: Asymmetry. 6: 1957-1963. DOI: 10.1016/0957-4166(95)00255-N |
0.636 |
|
| 1995 |
Cardillo G, Gentilucci L, Tomasini C, Tomasoni L. Synthesis of new chiral auxiliaries derived from (S)-tryptophan Tetrahedron: Asymmetry. 6: 1947-1955. DOI: 10.1016/0957-4166(95)00254-M |
0.628 |
|
| 1995 |
Gentilucci L, Grijzen Y, Thijs L, Zwanenburg B. Convenient synthesis of optically active 2H-azirine-2-carboxylic esters by Swern oxidation of aziridine-2-carboxylic esters Tetrahedron Letters. 36: 4665-4668. DOI: 10.1016/0040-4039(95)00833-X |
0.455 |
|
| 1994 |
Cardillo G, De Simone A, Gentilucci L, Tomasini C. Conjugate addition of chloride to α,β-unsaturated chiral imides promoted by BCl3-derivatives. A synthesis of 3-chlorobutanoic acid Journal of the Chemical Society, Chemical Communications. 735-736. DOI: 10.1039/C39940000735 |
0.657 |
|
| 1994 |
Cardillo G, De Simone A, Gentilucci L, Sabatino P, Tomasini C. Michael-type addition of phthalimide salts to chiral α,β-unsaturated imides Tetrahedron Letters. 35: 5051-5054. DOI: 10.1016/S0040-4039(00)73317-X |
0.662 |
|
| 1992 |
Dhavale DD, Gentilucci L, Piazza MG, Trombinl C. Iodocyclization of Homoallylic Hydroxylamines Derived fromD-Glyceraldehyde Liebigs Annalen Der Chemie. 1992: 1289-1295. DOI: 10.1002/Jlac.1992199201213 |
0.35 |
|
| Show low-probability matches. |