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Thomas B. Poulsen, PhD - Publications

Affiliations: 
Aarhus University, Aarhus, Denmark 
Area:
Chemistry, Chemical Biology
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47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Liu Y, Izzo JA, McLeod D, Ričko S, Svenningsen EB, Poulsen TB, Jørgensen KA. Organocatalytic Asymmetric Multicomponent Cascade Reaction for the Synthesis of Contiguously Substituted Tetrahydronaphthols. Journal of the American Chemical Society. 143: 8208-8220. PMID 34028261 DOI: 10.1021/jacs.1c03923  0.759
2021 Poulsen TB. Total Synthesis of Natural Products Containing Enamine or Enol Ether Derivatives. Accounts of Chemical Research. PMID 33660974 DOI: 10.1021/acs.accounts.0c00851  0.346
2021 Wørmer GJ, Villadsen NL, Nørby P, Poulsen TB. Concise Asymmetric Syntheses of Streptazone A and Abikoviromycin*. Angewandte Chemie (International Ed. in English). PMID 33576128 DOI: 10.1002/anie.202101439  0.396
2021 Lin S, Liu H, Svenningsen EB, Wollesen M, Jacobsen KM, Andersen FD, Moyano-Villameriel J, Pedersen CN, Nørby P, Tørring T, Poulsen TB. Expanding the antibacterial selectivity of polyether ionophore antibiotics through diversity-focused semisynthesis. Nature Chemistry. 13: 47-55. PMID 33353970 DOI: 10.1038/s41557-020-00601-1  0.312
2020 Hjerrild P, Tørring T, Poulsen TB. Dehydration reactions in polyfunctional natural products. Natural Product Reports. PMID 32319503 DOI: 10.1039/D0Np00009D  0.331
2020 Hansen BK, Larsen CK, Nielsen JT, Svenningsen EB, Van LB, Jacobsen KM, Bjerring M, Flygaard RK, Jenner LB, Nejsum LN, Brodersen DE, Mulder FAA, Tørring T, Poulsen TB. Structure and Function of the Bacterial Protein Toxin Phenomycin. Structure (London, England : 1993). PMID 32220302 DOI: 10.1016/J.Str.2020.03.003  0.313
2019 Wørmer GJ, Hansen BK, Palmfeldt J, Poulsen TB. A Cyclopropene Electrophile that Targets Glutathione S-Transferase Omega-1 in Cells. Angewandte Chemie (International Ed. in English). PMID 31291041 DOI: 10.1002/Anie.201907520  0.363
2019 Liu H, Lin S, Jacobsen KM, Poulsen TB. Chemical syntheses and chemical genetics of carboxyl polyether ionophores: Recent highlights. Angewandte Chemie (International Ed. in English). PMID 30793459 DOI: 10.1002/Anie.201812982  0.332
2019 Hansen BK, Loveridge CJ, Thyssen S, Wørmer GJ, Nielsen AD, Palmfeldt J, Johannsen M, Poulsen TB. STEFs: Activated Vinylogous Protein-Reactive Electrophiles. Angewandte Chemie (International Ed. in English). PMID 30618057 DOI: 10.1002/Anie.201814073  0.384
2018 Jørgensen KA, Hammer N, Erickson JD, Lauridsen VH, Jacobseb JB, Hansen BK, Jacobsen KM, Poulsen TB. Catalytic Asymmetric [4+2]-Cycloadditions Using Tropolones: Developments, Scope, Transformations and Bioactivity. Angewandte Chemie (International Ed. in English). PMID 30133090 DOI: 10.1002/Anie.201808221  0.709
2018 Jacobsen KM, Villadsen NL, Tørring T, Nielsen CB, Salomón T, Nielsen MM, Tsakos M, Sibbersen C, Scavenius C, Nielsen R, Christensen EI, Guerra PF, Bross P, Pedersen JS, Enghild JJ, ... ... Poulsen TB, et al. APD-Containing Cyclolipodepsipeptides Target Mitochondrial Function in Hypoxic Cancer Cells. Cell Chemical Biology. PMID 30122371 DOI: 10.1016/J.Chembiol.2018.07.010  0.33
2018 Yu W, Hjerrild P, Jacobsen K, Tobiesen H, Clemmensen L, Poulsen TB. A Catalytic Oxidative Quinone Heterofunctionalization Method - Synthesis of Strongylophorine-26. Angewandte Chemie (International Ed. in English). PMID 29888861 DOI: 10.1002/Anie.201805580  0.337
2018 Villadsen NL, Hansen BK, Svenningsen EB, Jørgensen KH, Tørring T, Poulsen TB. Stendomycin and Pantomycin are Identical Natural Products - Preparation of a Functionalized Bioactive Analog. The Journal of Organic Chemistry. PMID 29724097 DOI: 10.1021/Acs.Joc.8B00553  0.324
2017 Salomón T, Sibbersen C, Hansen J, Britz D, Svart MV, Voss TS, Møller N, Gregersen N, Jørgensen KA, Palmfeldt J, Poulsen TB, Johannsen M. Ketone Body Acetoacetate Buffers Methylglyoxal via a Non-enzymatic Conversion during Diabetic and Dietary Ketosis. Cell Chemical Biology. 24: 935-943.e7. PMID 28820963 DOI: 10.1016/J.Chembiol.2017.07.012  0.488
2017 Holmquist EF, Bering Keiding U, Kold-Christensen R, Salomón T, Jørgensen KA, Kristensen P, Poulsen TB, Johannsen M. ReactELISA: Monitoring a Carbon Nucleophilic Metabolite by ELISA - a Study of Lipid Metabolism. Analytical Chemistry. PMID 28376300 DOI: 10.1021/Acs.Analchem.7B00507  0.521
2017 Villadsen NL, Jacobsen KM, Keiding UB, Weibel ET, Christiansen B, Vosegaard T, Bjerring M, Jensen F, Johannsen M, Tørring T, Poulsen TB. Synthesis of ent-BE-43547A1 reveals a potent hypoxia-selective anticancer agent and uncovers the biosynthetic origin of the APD-CLD natural products. Nature Chemistry. 9: 264-272. PMID 28221346 DOI: 10.1038/Nchem.2657  0.402
2016 Yu W, Hjerrild P, Overgaard J, Poulsen TB. A Concise Route to the Strongylophorines. Angewandte Chemie (International Ed. in English). PMID 27239800 DOI: 10.1002/Anie.201602476  0.355
2016 Poulsen T, Tsakos M, Jacobsen K, Yu W, Villadsen N. The Rakicidin Family of Anticancer Natural Products – Synthetic Strategies towards a New Class of Hypoxia-Selective Cytotoxins Synlett. 27: 1898-1906. DOI: 10.1055/S-0035-1561465  0.394
2016 Carreira EM, Zipfel HF, Tsakos M, Clement LL, Schaffert ES, Olsen FN, Rupiani S, Djurhuus R, Yu W, Jacobsen KM, Villadsen NL, Poulsen TB. Total Synthesis of Rakicidin A Synfacts. 12: 112-112. DOI: 10.1055/S-0035-1561118  0.349
2015 Tsakos M, Clement LL, Schaffert ES, Olsen FN, Rupiani S, Djurhuus R, Yu W, Jacobsen KM, Villadsen NL, Poulsen TB. Total Synthesis and Biological Evaluation of Rakicidin A and Discovery of a Simplified Bioactive Analogue. Angewandte Chemie (International Ed. in English). PMID 26637117 DOI: 10.1002/Anie.201509926  0.753
2015 Clement LL, Tsakos M, Schaffert ES, Scavenius C, Enghild JJ, Poulsen TB. The amido-pentadienoate-functionality of the rakicidins is a thiol reactive electrophile--development of a general synthetic strategy. Chemical Communications (Cambridge, England). 51: 12427-30. PMID 26146360 DOI: 10.1039/C5Cc04500B  0.384
2015 Tsakos M, Schaffert ES, Clement LL, Villadsen NL, Poulsen TB. Ester coupling reactions - an enduring challenge in the chemical synthesis of bioactive natural products. Natural Product Reports. 32: 605-32. PMID 25572105 DOI: 10.1039/C4Np00106K  0.389
2015 Olsen FN, Tsakos M, Poulsen TB. Npys-Mediated Elimination Reactions of Alcohols and Thiols: A Facile Route to Dehydroalanine and Dehydrobutyrine Building Blocks Synlett. 26: 2697-2701. DOI: 10.1055/S-0035-1560537  0.316
2011 Poulsen TB. A concise route to the macrocyclic core of the rakicidins. Chemical Communications (Cambridge, England). 47: 12837-9. PMID 22045383 DOI: 10.1039/C1Cc15829E  0.367
2011 Burgett AW, Poulsen TB, Wangkanont K, Anderson DR, Kikuchi C, Shimada K, Okubo S, Fortner KC, Mimaki Y, Kuroda M, Murphy JP, Schwalb DJ, Petrella EC, Cornella-Taracido I, Schirle M, et al. Natural products reveal cancer cell dependence on oxysterol-binding proteins. Nature Chemical Biology. 7: 639-47. PMID 21822274 DOI: 10.1038/Nchembio.625  0.639
2009 Dickmeiss G, De Sio V, Udmark J, Poulsen TB, Marcos V, Jørgensen KA. Organocatalytic asymmetric desymmetrization-fragmentation of cyclic ketones. Angewandte Chemie (International Ed. in English). 48: 6650-3. PMID 19658150 DOI: 10.1002/Anie.200903253  0.541
2009 Madsen CB, Madsen LB, Viftrup SS, Johansson MP, Poulsen TB, Holmegaard L, Kumarappan V, Jørgensen KA, Stapelfeldt H. A combined experimental and theoretical study on realizing and using laser controlled torsion of molecules. The Journal of Chemical Physics. 130: 234310. PMID 19548730 DOI: 10.1063/1.3149789  0.422
2009 Alberg DG, Poulsen TB, Bertelsen S, Christensen KL, Birkler RD, Johannsen M, Jørgensen KA. Organocatalysis with endogenous compounds: towards novel non-enzymatic reactions. Bioorganic & Medicinal Chemistry Letters. 19: 3888-91. PMID 19364643 DOI: 10.1016/J.Bmcl.2009.03.128  0.567
2009 Madsen CB, Madsen LB, Viftrup SS, Johansson MP, Poulsen TB, Holmegaard L, Kumarappan V, Jørgensen KA, Stapelfeldt H. Manipulating the torsion of molecules by strong laser pulses. Physical Review Letters. 102: 073007. PMID 19257667 DOI: 10.1103/Physrevlett.102.073007  0.422
2009 Dickmeiss G, Sio VD, Udmark J, Poulsen TB, Marcos V, Jørgensen KA. Desymmetrization of meso-Cyclopentanones Synfacts. 2009: 1155-1155. DOI: 10.1055/S-0029-1217948  0.471
2008 Poulsen TB, Jørgensen KA. Catalytic asymmetric Friedel-Crafts alkylation reactions--copper showed the way. Chemical Reviews. 108: 2903-15. PMID 18500844 DOI: 10.1021/Cr078372E  0.568
2008 Poulsen TB, Dickmeiss G, Overgaard J, Jørgensen KA. Organocatalytic asymmetric synthesis of versatile gamma-lactams. Angewandte Chemie (International Ed. in English). 47: 4687-90. PMID 18478619 DOI: 10.1002/Anie.200800329  0.528
2008 Poulsen TB, Dickmeiss G, Overgaard J, Jørgensen KA. Enantioselective Synthesis of g-Lactams Synfacts. 2008: 873-873. DOI: 10.1055/S-2008-1078542  0.487
2007 Santoro S, Poulsen TB, Jørgensen KA. Enantioselective organocatalytic substitution of alpha-cyanoacetates on imidoyl chlorides--synthesis of optically active ketimines. Chemical Communications (Cambridge, England). 5155-7. PMID 18060126 DOI: 10.1039/B715810F  0.727
2007 López-Cantarero J, Cid MB, Poulsen TB, Bella M, Ruano JL, Jørgensen KA. Intriguing behavior of cinchona alkaloids in the enantioselective organocatalytic hydroxyamination of alpha-substituted-alpha-cyanoacetates. The Journal of Organic Chemistry. 72: 7062-5. PMID 17685658 DOI: 10.1021/Jo071186O  0.694
2007 Bell M, Poulsen TB, Jørgensen KA. Organocatalytic enantioselective nucleophilic vinylic substitution by alpha-substituted-alpha-cyanoacetates under phase-transfer conditions. The Journal of Organic Chemistry. 72: 3053-6. PMID 17371076 DOI: 10.1021/JO070024P  0.551
2007 Poulsen TB, Bernardi L, Aleman J, Overgaard J, Jørgensen KA. Organocatalytic asymmetric direct alpha-alkynylation of cyclic beta-ketoesters. Journal of the American Chemical Society. 129: 441-9. PMID 17212424 DOI: 10.1021/Ja067289Q  0.741
2006 Poulsen TB, Bernardi L, Bell M, Jørgensen KA. Organocatalytic enantioselective nucleophilic vinylic substitution. Angewandte Chemie (International Ed. in English). 45: 6551-4. PMID 16953500 DOI: 10.1002/Anie.200602275  0.67
2006 Poulsen TB, Bell M, Jørgensen KA. Organocatalytic asymmetric allylic carbon-carbon bond formation. Organic & Biomolecular Chemistry. 4: 63-70. PMID 16357998 DOI: 10.1039/B514564C  0.555
2006 Jørgensen K, Poulsen T, Bernardi L, Bell M. Bulky Cinchonine Derivatives as Phase-Transfer Catalysts in Vinylic Substitution Reactions Synfacts. 2006: 1285-1285. DOI: 10.1055/S-2006-955558  0.652
2005 Zhuang W, Poulsen TB, Jørgensen KA. A versatile catalyst for asymmetric reactions of carbonyl groups working purely by activation through hydrogen bonding: Mukaiyama-aldol, hetero Diels-Alder and Friedel-Crafts reactions. Organic & Biomolecular Chemistry. 3: 3284-9. PMID 16132090 DOI: 10.1039/B507778H  0.59
2005 Poulsen TB, Alemparte C, Jørgensen KA. Enantioselective organocatalytic allylic amination. Journal of the American Chemical Society. 127: 11614-5. PMID 16104733 DOI: 10.1021/Ja0539847  0.621
2005 Marigo M, Franzén J, Poulsen TB, Zhuang W, Jørgensen KA. Asymmetric organocatalytic epoxidation of alpha,beta-unsaturated aldehydes with hydrogen peroxide. Journal of the American Chemical Society. 127: 6964-5. PMID 15884935 DOI: 10.1021/Ja051808S  0.582
2005 Poulsen TB, Alemparte C, Saaby S, Bella M, Jørgensen KA. Direct organocatalytic and highly enantio- and diastereoselective Mannich reactions of alpha-substituted alpha-cyanoacetates. Angewandte Chemie (International Ed. in English). 44: 2896-9. PMID 15827948 DOI: 10.1002/Anie.200500144  0.657
2005 Marigo M, Franzen J, Poulsen TB, Zhuang W, Jørgensen KA. Asymmetric Organocatalytic Epoxidation of α,β-Unsaturated Aldehydes Synfacts. 2005: 76-76. DOI: 10.1055/S-2005-869988  0.44
2004 Gathergood N, Juhl K, Poulsen TB, Thordrup K, Jørgensen KA. Direct catalytic asymmetric aldol reactions of pyruvates: scope and mechanism. Organic & Biomolecular Chemistry. 2: 1077-85. PMID 15034632 DOI: 10.1039/B316092K  0.6
2003 Bøgevig A, Poulsen TB, Zhuang W, Jørgensen KA. Formation of optically active functionalized β-hydroxy nitrones using a proline catalyzed aldol reaction of aldehydes with carbonyl compounds and hydroxylamines Synlett. 2003: 1915-1918. DOI: 10.1055/S-2003-41479  0.568
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