Linda Van Aelst - Publications

Affiliations: 
Neuroscience Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 

34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Ge EJ, Bush AI, Casini A, Cobine PA, Cross JR, DeNicola GM, Dou QP, Franz KJ, Gohil VM, Gupta S, Kaler SG, Lutsenko S, Mittal V, Petris MJ, Polishchuk R, ... ... Van Aelst L, et al. Connecting copper and cancer: from transition metal signalling to metalloplasia. Nature Reviews. Cancer. PMID 34764459 DOI: 10.1038/s41568-021-00417-2  0.574
2017 Nakamuta S, Yang YT, Wang CL, Gallo NB, Yu JR, Tai Y, Van Aelst L. Dual role for DOCK7 in tangential migration of interneuron precursors in the postnatal forebrain. The Journal of Cell Biology. PMID 29089377 DOI: 10.1083/Jcb.201704157  0.313
2014 Nakano-Kobayashi A, Tai Y, Nadif Kasri N, Van Aelst L. The X-linked mental retardation protein OPHN1 interacts with Homer1b/c to control spine endocytic zone positioning and expression of synaptic potentiation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 8665-71. PMID 24966368 DOI: 10.1523/JNEUROSCI.0894-14.2014  0.653
2013 Anne SL, Govek EE, Ayrault O, Kim JH, Zhu X, Murphy DA, Van Aelst L, Roussel MF, Hatten ME. WNT3 inhibits cerebellar granule neuron progenitor proliferation and medulloblastoma formation via MAPK activation. Plos One. 8: e81769. PMID 24303070 DOI: 10.1371/Journal.Pone.0081769  0.7
2012 Yang YT, Wang CL, Van Aelst L. DOCK7 interacts with TACC3 to regulate interkinetic nuclear migration and cortical neurogenesis. Nature Neuroscience. 15: 1201-10. PMID 22842144 DOI: 10.1038/Nn.3171  0.311
2011 Nadif Kasri N, Nakano-Kobayashi A, Van Aelst L. Rapid synthesis of the X-linked mental retardation protein OPHN1 mediates mGluR-dependent LTD through interaction with the endocytic machinery. Neuron. 72: 300-15. PMID 22017989 DOI: 10.1016/j.neuron.2011.09.001  0.668
2011 Govek EE, Hatten ME, Van Aelst L. The role of Rho GTPase proteins in CNS neuronal migration. Developmental Neurobiology. 71: 528-53. PMID 21557504 DOI: 10.1002/dneu.20850  0.687
2010 Svitkina T, Lin WH, Webb DJ, Yasuda R, Wayman GA, Van Aelst L, Soderling SH. Regulation of the postsynaptic cytoskeleton: roles in development, plasticity, and disorders. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14937-42. PMID 21068295 DOI: 10.1523/Jneurosci.4276-10.2010  0.355
2010 Nadif Kasri N, Van Aelst L. Spines and Mental Disorders Encyclopedia of Neuroscience. 329-335. DOI: 10.1016/B978-008045046-9.01797-6  0.596
2009 Nadif Kasri N, Nakano-Kobayashi A, Malinow R, Li B, Van Aelst L. The Rho-linked mental retardation protein oligophrenin-1 controls synapse maturation and plasticity by stabilizing AMPA receptors. Genes & Development. 23: 1289-302. PMID 19487570 DOI: 10.1101/Gad.1783809  0.659
2008 Hu H, Qin Y, Bochorishvili G, Zhu Y, van Aelst L, Zhu JJ. Ras signaling mechanisms underlying impaired GluR1-dependent plasticity associated with fragile X syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 7847-62. PMID 18667617 DOI: 10.1523/Jneurosci.1496-08.2008  0.338
2008 Kasri NN, Govek EE, Van Aelst L. Characterization of oligophrenin-1, a RhoGAP lost in patients affected with mental retardation: lentiviral injection in organotypic brain slice cultures. Methods in Enzymology. 439: 255-66. PMID 18374170 DOI: 10.1016/S0076-6879(07)00419-3  0.693
2008 Nadif Kasri N, Van Aelst L. Rho-linked genes and neurological disorders. Pflã¼Gers Archiv : European Journal of Physiology. 455: 787-97. PMID 18004590 DOI: 10.1007/s00424-007-0385-1  0.685
2006 Watabe-Uchida M, Govek EE, Van Aelst L. Regulators of Rho GTPases in neuronal development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 10633-5. PMID 17050702 DOI: 10.1523/Jneurosci.4084-06.2006  0.684
2006 Zhao M, Janas JA, Niki M, Pandolfi PP, Van Aelst L. Dok-1 independently attenuates Ras/mitogen-activated protein kinase and Src/c-myc pathways to inhibit platelet-derived growth factor-induced mitogenesis. Molecular and Cellular Biology. 26: 2479-89. PMID 16537894 DOI: 10.1128/Mcb.26.7.2479-2489.2006  0.536
2005 Qin Y, Zhu Y, Baumgart JP, Stornetta RL, Seidenman K, Mack V, van Aelst L, Zhu JJ. State-dependent Ras signaling and AMPA receptor trafficking. Genes & Development. 19: 2000-15. PMID 16107614 DOI: 10.1101/Gad.342205  0.307
2005 Newey SE, Velamoor V, Govek EE, Van Aelst L. Rho GTPases, dendritic structure, and mental retardation. Journal of Neurobiology. 64: 58-74. PMID 15884002 DOI: 10.1002/Neu.20153  0.722
2005 Govek EE, Newey SE, Van Aelst L. The role of the Rho GTPases in neuronal development. Genes & Development. 19: 1-49. PMID 15630019 DOI: 10.1101/Gad.1256405  0.704
2004 Niki M, Di Cristofano A, Zhao M, Honda H, Hirai H, Van Aelst L, Cordon-Cardo C, Pandolfi PP. Role of Dok-1 and Dok-2 in leukemia suppression. The Journal of Experimental Medicine. 200: 1689-95. PMID 15611295 DOI: 10.1084/Jem.20041306  0.493
2004 Van Aelst L, Cline HT. Rho GTPases and activity-dependent dendrite development. Current Opinion in Neurobiology. 14: 297-304. PMID 15194109 DOI: 10.1016/j.conb.2004.05.012  0.318
2004 Govek EE, Newey SE, Akerman CJ, Cross JR, Van der Veken L, Van Aelst L. The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesis. Nature Neuroscience. 7: 364-72. PMID 15034583 DOI: 10.1038/Nn1210  0.754
2003 Boettner B, Harjes P, Ishimaru S, Heke M, Fan HQ, Qin Y, Van Aelst L, Gaul U. The AF-6 homolog canoe acts as a Rap1 effector during dorsal closure of the Drosophila embryo. Genetics. 165: 159-69. PMID 14504224  0.309
2002 Zhu JJ, Qin Y, Zhao M, Van Aelst L, Malinow R. Ras and Rap control AMPA receptor trafficking during synaptic plasticity. Cell. 110: 443-55. PMID 12202034 DOI: 10.1016/S0092-8674(02)00897-8  0.492
2002 Van Aelst L, Symons M. Role of Rho family GTPases in epithelial morphogenesis. Genes & Development. 16: 1032-54. PMID 12000787 DOI: 10.1101/Gad.978802  0.365
2002 Boettner B, Van Aelst L. The role of Rho GTPases in disease development. Gene. 286: 155-74. PMID 11943472 DOI: 10.1016/S0378-1119(02)00426-2  0.336
2001 Di Cristofano A, Niki M, Zhao M, Karnell FG, Clarkson B, Pear WS, Van Aelst L, Pandolfi PP. p62(dok), a negative regulator of Ras and mitogen-activated protein kinase (MAPK) activity, opposes leukemogenesis by p210(bcr-abl). The Journal of Experimental Medicine. 194: 275-84. PMID 11489947 DOI: 10.1084/Jem.194.3.275  0.46
2001 Zhao M, Schmitz AA, Qin Y, Di Cristofano A, Pandolfi PP, Van Aelst L. Phosphoinositide 3-kinase-dependent membrane recruitment of p62(dok) is essential for its negative effect on mitogen-activated protein (MAP) kinase activation. The Journal of Experimental Medicine. 194: 265-74. PMID 11489946 DOI: 10.1084/Jem.194.3.265  0.505
2000 Schmitz AA, Govek EE, Böttner B, Van Aelst L. Rho GTPases: signaling, migration, and invasion. Experimental Cell Research. 261: 1-12. PMID 11082269 DOI: 10.1006/excr.2000.5049  0.696
2000 Boettner B, Govek EE, Cross J, Van Aelst L. The junctional multidomain protein AF-6 is a binding partner of the Rap1A GTPase and associates with the actin cytoskeletal regulator profilin. Proceedings of the National Academy of Sciences of the United States of America. 97: 9064-9. PMID 10922060 DOI: 10.1073/Pnas.97.16.9064  0.712
2000 Li Z, Van Aelst L, Cline HT. Rho GTPases regulate distinct aspects of dendritic arbor growth in Xenopus central neurons in vivo. Nature Neuroscience. 3: 217-25. PMID 10700252 DOI: 10.1038/72920  0.378
1997 D'Souza-Schorey C, Boshans RL, McDonough M, Stahl PD, Van Aelst L. A role for POR1, a Rac1-interacting protein, in ARF6-mediated cytoskeletal rearrangements. The Embo Journal. 16: 5445-54. PMID 9312003 DOI: 10.1093/Emboj/16.17.5445  0.304
1997 Van Aelst L, D'Souza-Schorey C. Rho GTPases and signaling networks. Genes & Development. 11: 2295-322. PMID 9308960 DOI: 10.1101/Gad.11.18.2295  0.329
1997 Westwick JK, Lambert QT, Clark GJ, Symons M, Van Aelst L, Pestell RG, Der CJ. Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways. Molecular and Cellular Biology. 17: 1324-35. PMID 9032259 DOI: 10.1128/Mcb.17.3.1324  0.329
1996 Joneson T, McDonough M, Bar-Sagi D, Van Aelst L. RAC regulation of actin polymerization and proliferation by a pathway distinct from Jun kinase. Science (New York, N.Y.). 274: 1374-6. PMID 8910277 DOI: 10.1126/Science.274.5291.1374  0.698
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