| Year |
Citation |
Score |
| 2023 |
Ogawa Y, Lim BC, George S, Oses-Prieto JA, Rasband JM, Eshed-Eisenbach Y, Hamdan H, Nair S, Boato F, Peles E, Burlingame AL, Van Aelst L, Rasband MN. Antibody-directed extracellular proximity biotinylation reveals that Contactin-1 regulates axo-axonic innervation of axon initial segments. Nature Communications. 14: 6797. PMID 37884508 DOI: 10.1038/s41467-023-42273-8 |
0.727 |
|
| 2021 |
Ge EJ, Bush AI, Casini A, Cobine PA, Cross JR, DeNicola GM, Dou QP, Franz KJ, Gohil VM, Gupta S, Kaler SG, Lutsenko S, Mittal V, Petris MJ, Polishchuk R, ... ... Van Aelst L, et al. Connecting copper and cancer: from transition metal signalling to metalloplasia. Nature Reviews. Cancer. PMID 34764459 DOI: 10.1038/s41568-021-00417-2 |
0.557 |
|
| 2021 |
Wang M, Gallo NB, Tai Y, Li B, Van Aelst L. Oligophrenin-1 moderates behavioral responses to stress by regulating parvalbumin interneuron activity in the medial prefrontal cortex. Neuron. PMID 33831348 DOI: 10.1016/j.neuron.2021.03.016 |
0.43 |
|
| 2019 |
Tai Y, Gallo NB, Wang M, Yu JR, Van Aelst L. Axo-axonic Innervation of Neocortical Pyramidal Neurons by GABAergic Chandelier Cells Requires AnkyrinG-Associated L1CAM. Neuron. PMID 30846310 DOI: 10.1016/j.neuron.2019.02.009 |
0.446 |
|
| 2015 |
Penzo MA, Robert V, Tucciarone J, De Bundel D, Wang M, Van Aelst L, Darvas M, Parada LF, Palmiter RD, He M, Huang ZJ, Li B. The paraventricular thalamus controls a central amygdala fear circuit. Nature. 519: 455-9. PMID 25600269 DOI: 10.1038/Nature13978 |
0.454 |
|
| 2014 |
Nakano-Kobayashi A, Tai Y, Nadif Kasri N, Van Aelst L. The X-linked mental retardation protein OPHN1 interacts with Homer1b/c to control spine endocytic zone positioning and expression of synaptic potentiation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 8665-71. PMID 24966368 DOI: 10.1523/JNEUROSCI.0894-14.2014 |
0.626 |
|
| 2013 |
Anne SL, Govek EE, Ayrault O, Kim JH, Zhu X, Murphy DA, Van Aelst L, Roussel MF, Hatten ME. WNT3 inhibits cerebellar granule neuron progenitor proliferation and medulloblastoma formation via MAPK activation. Plos One. 8: e81769. PMID 24303070 DOI: 10.1371/Journal.Pone.0081769 |
0.703 |
|
| 2011 |
Nadif Kasri N, Nakano-Kobayashi A, Van Aelst L. Rapid synthesis of the X-linked mental retardation protein OPHN1 mediates mGluR-dependent LTD through interaction with the endocytic machinery. Neuron. 72: 300-15. PMID 22017989 DOI: 10.1016/j.neuron.2011.09.001 |
0.643 |
|
| 2011 |
Govek EE, Hatten ME, Van Aelst L. The role of Rho GTPase proteins in CNS neuronal migration. Developmental Neurobiology. 71: 528-53. PMID 21557504 DOI: 10.1002/dneu.20850 |
0.684 |
|
| 2010 |
Nadif Kasri N, Van Aelst L. Spines and Mental Disorders Encyclopedia of Neuroscience. 329-335. DOI: 10.1016/B978-008045046-9.01797-6 |
0.563 |
|
| 2009 |
Nadif Kasri N, Nakano-Kobayashi A, Malinow R, Li B, Van Aelst L. The Rho-linked mental retardation protein oligophrenin-1 controls synapse maturation and plasticity by stabilizing AMPA receptors. Genes & Development. 23: 1289-302. PMID 19487570 DOI: 10.1101/Gad.1783809 |
0.645 |
|
| 2008 |
Hu H, Qin Y, Bochorishvili G, Zhu Y, van Aelst L, Zhu JJ. Ras signaling mechanisms underlying impaired GluR1-dependent plasticity associated with fragile X syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 7847-62. PMID 18667617 DOI: 10.1523/Jneurosci.1496-08.2008 |
0.327 |
|
| 2008 |
Kasri NN, Govek EE, Van Aelst L. Characterization of oligophrenin-1, a RhoGAP lost in patients affected with mental retardation: lentiviral injection in organotypic brain slice cultures. Methods in Enzymology. 439: 255-66. PMID 18374170 DOI: 10.1016/S0076-6879(07)00419-3 |
0.684 |
|
| 2008 |
Nadif Kasri N, Van Aelst L. Rho-linked genes and neurological disorders. Pflã¼Gers Archiv : European Journal of Physiology. 455: 787-97. PMID 18004590 DOI: 10.1007/s00424-007-0385-1 |
0.652 |
|
| 2006 |
Watabe-Uchida M, Govek EE, Van Aelst L. Regulators of Rho GTPases in neuronal development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 10633-5. PMID 17050702 DOI: 10.1523/Jneurosci.4084-06.2006 |
0.69 |
|
| 2006 |
Zhao M, Janas JA, Niki M, Pandolfi PP, Van Aelst L. Dok-1 independently attenuates Ras/mitogen-activated protein kinase and Src/c-myc pathways to inhibit platelet-derived growth factor-induced mitogenesis. Molecular and Cellular Biology. 26: 2479-89. PMID 16537894 DOI: 10.1128/Mcb.26.7.2479-2489.2006 |
0.526 |
|
| 2005 |
Qin Y, Zhu Y, Baumgart JP, Stornetta RL, Seidenman K, Mack V, van Aelst L, Zhu JJ. State-dependent Ras signaling and AMPA receptor trafficking. Genes & Development. 19: 2000-15. PMID 16107614 DOI: 10.1101/Gad.342205 |
0.322 |
|
| 2005 |
Newey SE, Velamoor V, Govek EE, Van Aelst L. Rho GTPases, dendritic structure, and mental retardation. Journal of Neurobiology. 64: 58-74. PMID 15884002 DOI: 10.1002/Neu.20153 |
0.706 |
|
| 2005 |
Govek EE, Newey SE, Van Aelst L. The role of the Rho GTPases in neuronal development. Genes & Development. 19: 1-49. PMID 15630019 DOI: 10.1101/Gad.1256405 |
0.698 |
|
| 2004 |
Niki M, Di Cristofano A, Zhao M, Honda H, Hirai H, Van Aelst L, Cordon-Cardo C, Pandolfi PP. Role of Dok-1 and Dok-2 in leukemia suppression. The Journal of Experimental Medicine. 200: 1689-95. PMID 15611295 DOI: 10.1084/Jem.20041306 |
0.472 |
|
| 2004 |
Govek EE, Newey SE, Akerman CJ, Cross JR, Van der Veken L, Van Aelst L. The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesis. Nature Neuroscience. 7: 364-72. PMID 15034583 DOI: 10.1038/Nn1210 |
0.756 |
|
| 2003 |
Boettner B, Harjes P, Ishimaru S, Heke M, Fan HQ, Qin Y, Van Aelst L, Gaul U. The AF-6 homolog canoe acts as a Rap1 effector during dorsal closure of the Drosophila embryo. Genetics. 165: 159-69. PMID 14504224 |
0.308 |
|
| 2002 |
Zhu JJ, Qin Y, Zhao M, Van Aelst L, Malinow R. Ras and Rap control AMPA receptor trafficking during synaptic plasticity. Cell. 110: 443-55. PMID 12202034 DOI: 10.1016/S0092-8674(02)00897-8 |
0.47 |
|
| 2002 |
Van Aelst L, Symons M. Role of Rho family GTPases in epithelial morphogenesis. Genes & Development. 16: 1032-54. PMID 12000787 DOI: 10.1101/Gad.978802 |
0.343 |
|
| 2002 |
Boettner B, Van Aelst L. The role of Rho GTPases in disease development. Gene. 286: 155-74. PMID 11943472 DOI: 10.1016/S0378-1119(02)00426-2 |
0.319 |
|
| 2001 |
Di Cristofano A, Niki M, Zhao M, Karnell FG, Clarkson B, Pear WS, Van Aelst L, Pandolfi PP. p62(dok), a negative regulator of Ras and mitogen-activated protein kinase (MAPK) activity, opposes leukemogenesis by p210(bcr-abl). The Journal of Experimental Medicine. 194: 275-84. PMID 11489947 DOI: 10.1084/Jem.194.3.275 |
0.444 |
|
| 2001 |
Zhao M, Schmitz AA, Qin Y, Di Cristofano A, Pandolfi PP, Van Aelst L. Phosphoinositide 3-kinase-dependent membrane recruitment of p62(dok) is essential for its negative effect on mitogen-activated protein (MAP) kinase activation. The Journal of Experimental Medicine. 194: 265-74. PMID 11489946 DOI: 10.1084/Jem.194.3.265 |
0.488 |
|
| 2000 |
Schmitz AA, Govek EE, Böttner B, Van Aelst L. Rho GTPases: signaling, migration, and invasion. Experimental Cell Research. 261: 1-12. PMID 11082269 DOI: 10.1006/excr.2000.5049 |
0.697 |
|
| 2000 |
Boettner B, Govek EE, Cross J, Van Aelst L. The junctional multidomain protein AF-6 is a binding partner of the Rap1A GTPase and associates with the actin cytoskeletal regulator profilin. Proceedings of the National Academy of Sciences of the United States of America. 97: 9064-9. PMID 10922060 DOI: 10.1073/Pnas.97.16.9064 |
0.738 |
|
| 2000 |
Li Z, Van Aelst L, Cline HT. Rho GTPases regulate distinct aspects of dendritic arbor growth in Xenopus central neurons in vivo. Nature Neuroscience. 3: 217-25. PMID 10700252 DOI: 10.1038/72920 |
0.339 |
|
| 1998 |
Webb CP, Van Aelst L, Wigler MH, Vande Woude GF. Signaling pathways in Ras-mediated tumorigenicity and metastasis. Proceedings of the National Academy of Sciences of the United States of America. 95: 8773-8. PMID 9671754 DOI: 10.1073/pnas.95.15.8773 |
0.557 |
|
| 1997 |
Van Aelst L, D'Souza-Schorey C. Rho GTPases and signaling networks. Genes & Development. 11: 2295-322. PMID 9308960 DOI: 10.1101/Gad.11.18.2295 |
0.332 |
|
| 1997 |
Westwick JK, Lambert QT, Clark GJ, Symons M, Van Aelst L, Pestell RG, Der CJ. Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways. Molecular and Cellular Biology. 17: 1324-35. PMID 9032259 DOI: 10.1128/Mcb.17.3.1324 |
0.332 |
|
| 1996 |
Joneson T, McDonough M, Bar-Sagi D, Van Aelst L. RAC regulation of actin polymerization and proliferation by a pathway distinct from Jun kinase. Science (New York, N.Y.). 274: 1374-6. PMID 8910277 DOI: 10.1126/Science.274.5291.1374 |
0.707 |
|
| 1996 |
Barr MM, Tu H, Van Aelst L, Wigler M. Identification of Ste4 as a potential regulator of Byr2 in the sexual response pathway of Schizosaccharomyces pombe. Molecular and Cellular Biology. 16: 5597-603. PMID 8816472 DOI: 10.1128/Mcb.16.10.5597 |
0.513 |
|
| 1996 |
Khosravi-Far R, White MA, Westwick JK, Solski PA, Chrzanowska-Wodnicka M, Van Aelst L, Wigler MH, Der CJ. Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation. Molecular and Cellular Biology. 16: 3923-33. PMID 8668210 DOI: 10.1128/Mcb.16.7.3923 |
0.554 |
|
| 1995 |
White MA, Nicolette C, Minden A, Polverino A, Van Aelst L, Karin M, Wigler MH. Multiple Ras functions can contribute to mammalian cell transformation. Cell. 80: 533-41. PMID 7867061 DOI: 10.1016/0092-8674(95)90507-3 |
0.528 |
|
| 1994 |
Jung V, Wei W, Ballester R, Camonis J, Mi S, Van Aelst L, Wigler M, Broek D. Two types of RAS mutants that dominantly interfere with activators of RAS. Molecular and Cellular Biology. 14: 3707-18. PMID 8196614 DOI: 10.1128/Mcb.14.6.3707 |
0.518 |
|
| 1994 |
Van Aelst L, White MA, Wigler MH. Ras partners. Cold Spring Harbor Symposia On Quantitative Biology. 59: 181-6. PMID 7587068 |
0.489 |
|
| 1993 |
Chardin P, Camonis JH, Gale NW, van Aelst L, Schlessinger J, Wigler MH, Bar-Sagi D. Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2. Science (New York, N.Y.). 260: 1338-43. PMID 8493579 DOI: 10.1126/Science.8493579 |
0.557 |
|
| 1993 |
Van Aelst L, Barr M, Marcus S, Polverino A, Wigler M. Complex formation between RAS and RAF and other protein kinases. Proceedings of the National Academy of Sciences of the United States of America. 90: 6213-7. PMID 8327501 DOI: 10.1073/Pnas.90.13.6213 |
0.561 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2012 |
Yang YT, Wang CL, Van Aelst L. DOCK7 interacts with TACC3 to regulate interkinetic nuclear migration and cortical neurogenesis. Nature Neuroscience. 15: 1201-10. PMID 22842144 DOI: 10.1038/Nn.3171 |
0.297 |
|
| 2010 |
Svitkina T, Lin WH, Webb DJ, Yasuda R, Wayman GA, Van Aelst L, Soderling SH. Regulation of the postsynaptic cytoskeleton: roles in development, plasticity, and disorders. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14937-42. PMID 21068295 DOI: 10.1523/Jneurosci.4276-10.2010 |
0.297 |
|
| 2000 |
Chen RA, Michaeli T, Van Aelst L, Ballester R. A role for the noncatalytic N terminus in the function of Cdc25, a Saccharomyces cerevisiae Ras-guanine nucleotide exchange factor. Genetics. 154: 1473-84. PMID 10747046 |
0.296 |
|
| 2017 |
Nakamuta S, Yang YT, Wang CL, Gallo NB, Yu JR, Tai Y, Van Aelst L. Dual role for DOCK7 in tangential migration of interneuron precursors in the postnatal forebrain. The Journal of Cell Biology. PMID 29089377 DOI: 10.1083/Jcb.201704157 |
0.295 |
|
| 1997 |
D'Souza-Schorey C, Boshans RL, McDonough M, Stahl PD, Van Aelst L. A role for POR1, a Rac1-interacting protein, in ARF6-mediated cytoskeletal rearrangements. The Embo Journal. 16: 5445-54. PMID 9312003 DOI: 10.1093/Emboj/16.17.5445 |
0.292 |
|
| 2007 |
Boettner B, Van Aelst L. The Rap GTPase activator Drosophila PDZ-GEF regulates cell shape in epithelial migration and morphogenesis. Molecular and Cellular Biology. 27: 7966-80. PMID 17846121 DOI: 10.1128/MCB.01275-07 |
0.29 |
|
| 1998 |
D'Souza-Schorey C, Boettner B, Van Aelst L. Rac regulates integrin-mediated spreading and increased adhesion of T lymphocytes. Molecular and Cellular Biology. 18: 3936-46. PMID 9632778 |
0.29 |
|
| 2006 |
Yasuda R, Harvey CD, Zhong H, Sobczyk A, van Aelst L, Svoboda K. Supersensitive Ras activation in dendrites and spines revealed by two-photon fluorescence lifetime imaging. Nature Neuroscience. 9: 283-91. PMID 16429133 DOI: 10.1038/Nn1635 |
0.289 |
|
| 2006 |
Watabe-Uchida M, John KA, Janas JA, Newey SE, Van Aelst L. The Rac activator DOCK7 regulates neuronal polarity through local phosphorylation of stathmin/Op18. Neuron. 51: 727-39. PMID 16982419 DOI: 10.1016/j.neuron.2006.07.020 |
0.287 |
|
| 2004 |
Van Aelst L, Cline HT. Rho GTPases and activity-dependent dendrite development. Current Opinion in Neurobiology. 14: 297-304. PMID 15194109 DOI: 10.1016/j.conb.2004.05.012 |
0.284 |
|
| 2009 |
Nakano-Kobayashi A, Kasri NN, Newey SE, Van Aelst L. The Rho-linked mental retardation protein OPHN1 controls synaptic vesicle endocytosis via endophilin A1. Current Biology : Cb. 19: 1133-9. PMID 19481455 DOI: 10.1016/j.cub.2009.05.022 |
0.283 |
|
| 2012 |
Zhang XC, Piccini A, Myers MP, Van Aelst L, Tonks NK. Functional analysis of the protein phosphatase activity of PTEN. The Biochemical Journal. 444: 457-64. PMID 22413754 DOI: 10.1042/Bj20120098 |
0.283 |
|
| 1996 |
Van Aelst L, Joneson T, Bar-Sagi D. Identification of a novel Rac1-interacting protein involved in membrane ruffling. The Embo Journal. 15: 3778-86. PMID 8670882 DOI: 10.1002/J.1460-2075.1996.Tb00751.X |
0.27 |
|
| 2000 |
Boshans RL, Szanto S, van Aelst L, D'Souza-Schorey C. ADP-ribosylation factor 6 regulates actin cytoskeleton remodeling in coordination with Rac1 and RhoA. Molecular and Cellular Biology. 20: 3685-94. PMID 10779358 DOI: 10.1128/Mcb.20.10.3685-3694.2000 |
0.268 |
|
| 2021 |
Cheng DK, Oni TE, Thalappillil JS, Park Y, Ting HC, Alagesan B, Prasad NV, Addison K, Rivera KD, Pappin DJ, Van Aelst L, Tuveson DA. Oncogenic KRAS engages an RSK1/NF1 pathway to inhibit wild-type RAS signaling in pancreatic cancer. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34021083 DOI: 10.1073/pnas.2016904118 |
0.266 |
|
| 2009 |
Boettner B, Van Aelst L. Control of cell adhesion dynamics by Rap1 signaling. Current Opinion in Cell Biology. 21: 684-93. PMID 19615876 DOI: 10.1016/j.ceb.2009.06.004 |
0.264 |
|
| 1995 |
Yang SS, Van Aelst L, Bar-Sagi D. Differential interactions of human Sos1 and Sos2 with Grb2. The Journal of Biological Chemistry. 270: 18212-5. PMID 7629138 DOI: 10.1074/Jbc.270.31.18212 |
0.261 |
|
| 2022 |
Gallo NB, Berisha A, Van Aelst L. Microglia regulate chandelier cell axo-axonic synaptogenesis. Proceedings of the National Academy of Sciences of the United States of America. 119: e2114476119. PMID 35263225 DOI: 10.1073/pnas.2114476119 |
0.26 |
|
| 1998 |
Lin AW, Barradas M, Stone JC, van Aelst L, Serrano M, Lowe SW. Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling. Genes & Development. 12: 3008-19. PMID 9765203 |
0.259 |
|
| 1991 |
van Aelst L, Jans AW, Thevelein JM. Involvement of the CDC25 gene product in the signal transmission pathway of the glucose-induced RAS-mediated cAMP signal in the yeast Saccharomyces cerevisiae. Journal of General Microbiology. 137: 341-9. PMID 1849965 DOI: 10.1099/00221287-137-2-341 |
0.259 |
|
| 2015 |
Krishnan N, Krishnan K, Connors CR, Choy MS, Page R, Peti W, Van Aelst L, Shea SD, Tonks NK. PTP1B inhibition suggests a therapeutic strategy for Rett syndrome. The Journal of Clinical Investigation. 125: 3163-77. PMID 26214522 DOI: 10.1172/Jci80323 |
0.258 |
|
| 2001 |
Gumienny TL, Brugnera E, Tosello-Trampont AC, Kinchen JM, Haney LB, Nishiwaki K, Walk SF, Nemergut ME, Macara IG, Francis R, Schedl T, Qin Y, Van Aelst L, Hengartner MO, Ravichandran KS. CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration. Cell. 107: 27-41. PMID 11595183 DOI: 10.1016/S0092-8674(01)00520-7 |
0.258 |
|
| 2021 |
Ango F, Gallo NB, Van Aelst L. Molecular mechanisms of axo-axonic innervation. Current Opinion in Neurobiology. 69: 105-112. PMID 33862423 DOI: 10.1016/j.conb.2021.03.002 |
0.257 |
|
| 1997 |
Adra CN, Manor D, Ko JL, Zhu S, Horiuchi T, Van Aelst L, Cerione RA, Lim B. RhoGDIgamma: a GDP-dissociation inhibitor for Rho proteins with preferential expression in brain and pancreas. Proceedings of the National Academy of Sciences of the United States of America. 94: 4279-84. PMID 9113980 DOI: 10.1073/Pnas.94.9.4279 |
0.255 |
|
| 2014 |
Tai Y, Janas JA, Wang CL, Van Aelst L. Regulation of chandelier cell cartridge and bouton development via DOCK7-mediated ErbB4 activation. Cell Reports. 6: 254-63. PMID 24440718 DOI: 10.1016/J.Celrep.2013.12.034 |
0.254 |
|
| 1997 |
Han J, Das B, Wei W, Van Aelst L, Mosteller RD, Khosravi-Far R, Westwick JK, Der CJ, Broek D. Lck regulates Vav activation of members of the Rho family of GTPases. Molecular and Cellular Biology. 17: 1346-53. PMID 9032261 DOI: 10.1128/MCB.17.3.1346 |
0.253 |
|
| 2011 |
Janas JA, Van Aelst L. Oncogenic tyrosine kinases target Dok-1 for ubiquitin-mediated proteasomal degradation to promote cell transformation. Molecular and Cellular Biology. 31: 2552-65. PMID 21536658 DOI: 10.1128/MCB.05045-11 |
0.252 |
|
| 1998 |
Bagrodia S, Taylor SJ, Jordon KA, Van Aelst L, Cerione RA. A novel regulator of p21-activated kinases. The Journal of Biological Chemistry. 273: 23633-6. PMID 9726964 DOI: 10.1074/jbc.273.37.23633 |
0.252 |
|
| 1991 |
Van Aelst L, Hohmann S, Zimmermann FK, Jans AW, Thevelein JM. A yeast homologue of the bovine lens fibre MIP gene family complements the growth defect of a Saccharomyces cerevisiae mutant on fermentable sugars but not its defect in glucose-induced RAS-mediated cAMP signalling. The Embo Journal. 10: 2095-104. PMID 1648479 |
0.249 |
|
| 2004 |
Benitah SA, Valerón PF, van Aelst L, Marshall CJ, Lacal JC. Rho GTPases in human cancer: an unresolved link to upstream and downstream transcriptional regulation. Biochimica Et Biophysica Acta. 1705: 121-32. PMID 15588766 DOI: 10.1016/J.Bbcan.2004.10.002 |
0.245 |
|
| 2005 |
Zhu Y, Pak D, Qin Y, McCormack SG, Kim MJ, Baumgart JP, Velamoor V, Auberson YP, Osten P, van Aelst L, Sheng M, Zhu JJ. Rap2-JNK removes synaptic AMPA receptors during depotentiation. Neuron. 46: 905-16. PMID 15953419 DOI: 10.1016/J.Neuron.2005.06.022 |
0.227 |
|
| 1989 |
Thevelein JM, Beullens M, Mbonyi K, Van Aelst L. The glucose-induced CDC25- and RAS-mediated cAMP signal in the yeast Saccharomyces cerevisiae. Yeast (Chichester, England). 5: S421-5. PMID 2546336 |
0.227 |
|
| 2020 |
Gallo NB, Paul A, Van Aelst L. Shedding Light on Chandelier Cell Development, Connectivity, and Contribution to Neural Disorders. Trends in Neurosciences. PMID 32564887 DOI: 10.1016/J.Tins.2020.05.003 |
0.222 |
|
| 1990 |
Van Aelst L, Boy-Marcotte E, Camonis JH, Thevelein JM, Jacquet M. The C-terminal part of the CDC25 gene product plays a key role in signal transduction in the glucose-induced modulation of cAMP level in Saccharomyces cerevisiae. European Journal of Biochemistry / Febs. 193: 675-80. PMID 2174363 DOI: 10.1111/J.1432-1033.1990.TB19386.X |
0.221 |
|
| 2008 |
Sordella R, Van Aelst L. Dialogue between RhoA/ROCK and members of the Par complex in cell polarity. Developmental Cell. 14: 150-2. PMID 18267081 DOI: 10.1016/J.Devcel.2008.01.015 |
0.219 |
|
| 1990 |
Mbonyi K, van Aelst L, Argüelles JC, Jans AW, Thevelein JM. Glucose-induced hyperaccumulation of cyclic AMP and defective glucose repression in yeast strains with reduced activity of cyclic AMP-dependent protein kinase. Molecular and Cellular Biology. 10: 4518-23. PMID 2201893 |
0.209 |
|
| 2001 |
Boettner B, Herrmann C, Van Aelst L. Ras and Rap1 interaction with AF-6 effector target. Methods in Enzymology. 332: 151-68. PMID 11305093 DOI: 10.1016/S0076-6879(01)32199-7 |
0.191 |
|
| 1999 |
Boettner B, Van Aelst L. Rac and Cdc42 effectors. Progress in Molecular and Subcellular Biology. 22: 135-58. PMID 10081068 |
0.187 |
|
| 2023 |
de Ruiter Swain J, Michalopoulou E, Noch EK, Lukey MJ, Van Aelst L. Metabolic partitioning in the brain and its hijacking by glioblastoma. Genes & Development. PMID 37648371 DOI: 10.1101/gad.350693.123 |
0.176 |
|
| 1998 |
Van Aelst L. Two-hybrid analysis of Ras-Raf interactions. Methods in Molecular Biology (Clifton, N.J.). 84: 201-22. PMID 9666451 DOI: 10.1385/0-89603-488-7:201 |
0.174 |
|
| 2014 |
Murray DW, Didier S, Chan A, Paulino V, Van Aelst L, Ruggieri R, Tran NL, Byrne AT, Symons M. Guanine nucleotide exchange factor Dock7 mediates HGF-induced glioblastoma cell invasion via Rac activation. British Journal of Cancer. 110: 1307-15. PMID 24518591 DOI: 10.1038/Bjc.2014.39 |
0.173 |
|
| 2006 |
Sordella R, Van Aelst L. Driving actin dynamics under the influence of alcohol. Cell. 127: 37-9. PMID 17018272 DOI: 10.1016/J.Cell.2006.09.017 |
0.166 |
|
| 1998 |
Antonarakis SE, Van Aelst L. Mind the GAP, Rho, Rab and GDI. Nature Genetics. 19: 106-8. PMID 9620758 DOI: 10.1038/450 |
0.154 |
|
| 1990 |
Argüelles JC, Mbonyi K, Van Aelst L, Vanhalewyn M, Jans AW, Thevelein JM. Absence of glucose-induced cAMP signaling in the Saccharomyces cerevisiae mutants cat1 and cat3 which are deficient in derepression of glucose-repressible proteins. Archives of Microbiology. 154: 199-205. PMID 2169717 DOI: 10.1007/BF00423333 |
0.153 |
|
| 2014 |
Soderling SH, Van Aelst L. Principles driving the spatial organization of Rho GTPase signaling at synapses Ras Superfamily Small G Proteins: Biology and Mechanisms 1: General Features, Signaling. 395-419. DOI: 10.1007/978-3-7091-1806-1_17 |
0.152 |
|
| 2004 |
Jakubiec A, Notaise J, Tournier V, Héricourt F, Block MA, Drugeon G, van Aelst L, Jupin I. Assembly of turnip yellow mosaic virus replication complexes: interaction between the proteinase and polymerase domains of the replication proteins. Journal of Virology. 78: 7945-57. PMID 15254167 DOI: 10.1128/JVI.78.15.7945-7957.2004 |
0.15 |
|
| 2013 |
Boettner B, Van Aelst L. Introduction to the ECR special issue on the roles of small GTPases. Experimental Cell Research. 319: 2309. PMID 23872315 DOI: 10.1016/j.yexcr.2013.07.009 |
0.147 |
|
| 2012 |
Kang H, Davis-Dusenbery BN, Nguyen PH, Lal A, Lieberman J, Van Aelst L, Lagna G, Hata A. Bone morphogenetic protein 4 promotes vascular smooth muscle contractility by activating microRNA-21 (miR-21), which down-regulates expression of family of dedicator of cytokinesis (DOCK) proteins. The Journal of Biological Chemistry. 287: 3976-86. PMID 22158624 DOI: 10.1074/Jbc.M111.303156 |
0.144 |
|
| 2010 |
Van Aelst L, Caroni P. Signaling mechanisms. Current Opinion in Neurobiology. 20: 397-9. PMID 20732806 DOI: 10.1016/j.conb.2010.08.003 |
0.139 |
|
| 1993 |
Van Aelst L, Hohmann S, Bulaya B, de Koning W, Sierkstra L, Neves MJ, Luyten K, Alijo R, Ramos J, Coccetti P. Molecular cloning of a gene involved in glucose sensing in the yeast Saccharomyces cerevisiae. Molecular Microbiology. 8: 927-43. PMID 8355617 DOI: 10.1111/j.1365-2958.1993.tb01638.x |
0.132 |
|
| 2020 |
Fein MR, He XY, Almeida AS, Bružas E, Pommier A, Yan R, Eberhardt A, Fearon DT, Van Aelst L, Wilkinson JE, Dos Santos CO, Egeblad M. Cancer cell CCR2 orchestrates suppression of the adaptive immune response. The Journal of Experimental Medicine. 217. PMID 32667673 DOI: 10.1084/jem.20181551 |
0.128 |
|
| 2006 |
Janas J, Skowronski J, Van Aelst L. Lentiviral delivery of RNAi in hippocampal neurons. Methods in Enzymology. 406: 593-605. PMID 16472690 DOI: 10.1016/S0076-6879(06)06046-0 |
0.128 |
|
| 2015 |
Yu JR, Tai Y, Jin Y, Hammell MC, Wilkinson JE, Roe JS, Vakoc CR, Van Aelst L. TGF-β/Smad signaling through DOCK4 facilitates lung adenocarcinoma metastasis. Genes & Development. 29: 250-61. PMID 25644601 DOI: 10.1101/Gad.248963.114 |
0.123 |
|
| 2002 |
Schmitz AA, Lucito R, Van Aelst L. Using cDNA-representational difference analysis (cDNA-RDA) in combination with microarrays to identify Rac regulated genes. Methods in Molecular Biology (Clifton, N.J.). 189: 25-43. PMID 12094592 DOI: 10.1385/1-59259-281-3:025 |
0.115 |
|
| 2012 |
Hill CS, Van Aelst L. Signaling and gradients: what's going down? Current Opinion in Cell Biology. 24: 155-7. PMID 22429915 DOI: 10.1016/j.ceb.2012.03.001 |
0.11 |
|
| 2013 |
Vanassche T, Peetermans M, Van Aelst LN, Peetermans WE, Verhaegen J, Missiakas DM, Schneewind O, Hoylaerts MF, Verhamme P. The role of staphylothrombin-mediated fibrin deposition in catheter-related Staphylococcus aureus infections. The Journal of Infectious Diseases. 208: 92-100. PMID 23532100 DOI: 10.1093/Infdis/Jit130 |
0.103 |
|
| 2019 |
He XY, Ng D, Van Aelst L, Egeblad M. Stressing Out about Cancer Immunotherapy. Cancer Cell. 36: 468-470. PMID 31715130 DOI: 10.1016/j.ccell.2019.10.013 |
0.103 |
|
| 2013 |
Berger AH, Chen M, Morotti A, Janas JA, Niki M, Bronson RT, Taylor BS, Ladanyi M, Van Aelst L, Politi K, Varmus HE, Pandolfi PP. DOK2 inhibits EGFR-mutated lung adenocarcinoma. Plos One. 8: e79526. PMID 24255704 DOI: 10.1371/Journal.Pone.0079526 |
0.094 |
|
| 2015 |
Krishnan N, Krishnan K, Connors CR, Choy MS, Page R, Peti W, Van Aelst L, Shea SD, Tonks NK. PTP1B inhibition suggests a therapeutic strategy for Rett syndrome Journal of Clinical Investigation. 125: 3163-3177. DOI: 10.1172/JCI80323 |
0.077 |
|
| 2013 |
Vanhoutte D, van Almen GC, Van Aelst LN, Van Cleemput J, Droogné W, Jin Y, Van de Werf F, Carmeliet P, Vanhaecke J, Papageorgiou AP, Heymans S. Matricellular proteins and matrix metalloproteinases mark the inflammatory and fibrotic response in human cardiac allograft rejection. European Heart Journal. 34: 1930-41. PMID 23139380 DOI: 10.1093/eurheartj/ehs375 |
0.077 |
|
| 2024 |
He XY, Gao Y, Ng D, Michalopoulou E, George S, Adrover JM, Sun L, Albrengues J, Daßler-Plenker J, Han X, Wan L, Wu XS, Shui LS, Huang YH, Liu B, ... ... Van Aelst L, et al. Chronic stress increases metastasis via neutrophil-mediated changes to the microenvironment. Cancer Cell. PMID 38402610 DOI: 10.1016/j.ccell.2024.01.013 |
0.07 |
|
| 2015 |
Van Aelst LN, Voss S, Carai P, Van Leeuwen R, Vanhoutte D, Sanders-van Wijk S, Eurlings L, Swinnen M, Verheyen FK, Verbeken E, Nef H, Troidl C, Cook SA, Brunner-La Rocca HP, Möllmann H, et al. Osteoglycin prevents cardiac dilatation and dysfunction after myocardial infarction through infarct collagen strengthening. Circulation Research. 116: 425-36. PMID 25520363 DOI: 10.1161/CIRCRESAHA.116.304599 |
0.049 |
|
| 2015 |
Van Aelst LN, Summer G, Li S, Gupta SK, Heggermont W, De Vusser K, Carai P, Naesens M, Van Cleemput J, Van de Werf F, Vanhaecke J, Thum T, Waer M, Papageorgiou AP, Schroen B, et al. RNA Profiling in Human and Murine Transplanted Hearts: Identification and Validation of Therapeutic Targets for Acute Cardiac and Renal Allograft Rejection. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 26249758 DOI: 10.1111/ajt.13421 |
0.048 |
|
| 2014 |
Nagels W, Brabant S, Van Aelst L, Pollet P, Anné W, Goethals M. Percutaneous left cardiac sympathetic denervation in a patient with long-QT syndrome. Journal of Cardiothoracic and Vascular Anesthesia. 28: 1580-2. PMID 24120976 DOI: 10.1053/j.jvca.2013.06.006 |
0.022 |
|
| 2013 |
Van Aelst LN, Heymans S. MicroRNAs as biomarkers for ischemic heart disease. Journal of Cardiovascular Translational Research. 6: 458-70. PMID 23716129 DOI: 10.1007/s12265-013-9466-z |
0.01 |
|
| 2011 |
Cosyn J, Van Aelst L, Collaert B, Persson GR, De Bruyn H. The peri-implant sulcus compared with internal implant and suprastructure components: a microbiological analysis. Clinical Implant Dentistry and Related Research. 13: 286-95. PMID 19673920 DOI: 10.1111/j.1708-8208.2009.00220.x |
0.01 |
|
| 2008 |
Van Aelst L, Cosyn J, De Bruyn H. [Guidelines for periodontal diagnosis in Belgium]. Revue Belge De Mã©Decine Dentaire. 63: 59-63. PMID 18717452 |
0.01 |
|
| 2002 |
Boettner B, Van Aelst L. The RASputin effect. Genes & Development. 16: 2033-8. PMID 12183358 DOI: 10.1101/gad.1020602 |
0.01 |
|
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