Sudar Rajagopal - Publications

Affiliations: 
Duke University, Durham, NC 

96 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Nathan SD, Waxman A, Rajagopal S, Case A, Johri S, DuBrock H, De La Zerda DJ, Sahay S, King C, Melendres-Groves L, Smith P, Shen E, Edwards LD, Nelsen A, Tapson VF. Inhaled treprostinil and forced vital capacity in patients with interstitial lung disease and associated pulmonary hypertension: a post-hoc analysis of the INCREASE study. The Lancet. Respiratory Medicine. PMID 34214475 DOI: 10.1016/S2213-2600(21)00165-X  0.435
2021 Colebank MJ, Qureshi MU, Rajagopal S, Krasuski RA, Olufsen MS. A multiscale model of vascular function in chronic thromboembolic pulmonary hypertension. American Journal of Physiology. Heart and Circulatory Physiology. PMID 34142886 DOI: 10.1152/ajpheart.00086.2021  0.443
2021 Wang Z, Rankine L, Bier EA, Mummy D, Lu J, Church A, Tighe RM, Swaminathan A, Huang YT, Que LG, Mammarappallil JG, Rajagopal S, Driehuys B. Using Hyperpolarized Xe Gas Exchange MRI to Model the Regional Airspace, Membrane and Capillary Contributions to Diffusing Capacity. Journal of Applied Physiology (Bethesda, Md. : 1985). PMID 33734831 DOI: 10.1152/japplphysiol.00702.2020  0.424
2021 Tsai CF, Smith JS, Eiger DS, Martin K, Liu T, Smith RD, Shi T, Rajagopal S, Jacobs JM. Mass Spectrometry-Based Proteomics for Analysis of Hydrophilic Phosphopeptides. Methods in Molecular Biology (Clifton, N.J.). 2259: 247-257. PMID 33687720 DOI: 10.1007/978-1-0716-1178-4_16  0.524
2021 Alenezi F, Rajagopal S. The right atrium, more than a storehouse. International Journal of Cardiology. PMID 33548383 DOI: 10.1016/j.ijcard.2021.01.069  0.394
2021 Alba GA, Samokhin AO, Wang RS, Zhang YY, Wertheim BM, Arons E, Greenfield EA, Lundberg Slingsby MH, Ceglowski JR, Haley KJ, Bowman FP, Yu YR, Haney JC, Eng G, Mitchell RN, ... ... Rajagopal S, et al. NEDD9 is a Novel and Modifiable Mediator of Platelet-Endothelial Adhesion in the Pulmonary Circulation. American Journal of Respiratory and Critical Care Medicine. PMID 33523764 DOI: 10.1164/rccm.202003-0719OC  0.478
2021 Smith JS, Pack TF, Inoue A, Lee C, Zheng K, Choi I, Eiger DS, Warman A, Xiong X, Ma Z, Viswanathan G, Levitan IM, Rochelle LK, Staus DP, Snyder JC, ... ... Rajagopal S, et al. Noncanonical scaffolding of G and β-arrestin by G protein-coupled receptors. Science (New York, N.Y.). PMID 33479120 DOI: 10.1126/science.aay1833  0.807
2021 Ghadimi K, Cappiello J, Cooter M, Levy J, Schroder J, Bryner B, Shah S, Rajagopal S, Devore A, Patel C, Milano C. Inhaled Selective Pulmonary Vasodilators for Advanced Heart Failure Therapies The Journal of Heart and Lung Transplantation. 40: S12. DOI: 10.1016/J.HEALUN.2021.01.1766  0.372
2020 Lee C, Viswanathan G, Choi I, Jassal C, Kohlmann T, Rajagopal S. Beta-Arrestins and Receptor Signaling in the Vascular Endothelium. Biomolecules. 11. PMID 33374806 DOI: 10.3390/biom11010009  0.632
2020 Edmonston DL, Rajagopal S, Wolf M. Echocardiography to Screen for Pulmonary Hypertension in CKD. Kidney International Reports. 5: 2275-2283. PMID 33305121 DOI: 10.1016/j.ekir.2020.09.033  0.435
2020 Eiger DS, Boldizsar N, Honeycutt CC, Gardner J, Rajagopal S. Biased agonism at chemokine receptors. Cellular Signalling. 78: 109862. PMID 33249087 DOI: 10.1016/j.cellsig.2020.109862  0.607
2020 Snyder JC, Rajagopal S. Isoforms of GPCR proteins combine for diverse signalling. Nature. PMID 33149314 DOI: 10.1038/d41586-020-03001-0  0.561
2020 Virgincar RS, Nouls JC, Wang Z, Degan S, Qi Y, Xiong X, Rajagopal S, Driehuys B. Quantitative Xe MRI detects early impairment of gas-exchange in a rat model of pulmonary hypertension. Scientific Reports. 10: 7385. PMID 32355256 DOI: 10.1038/S41598-020-64361-1  0.452
2020 Yu YA, Malakhau Y, Yu CA, Phelan SJ, Cumming RI, Kan MJ, Mao L, Rajagopal S, Piantadosi CA, Gunn MD. Nonclassical Monocytes Sense Hypoxia, Regulate Pulmonary Vascular Remodeling, and Promote Pulmonary Hypertension. Journal of Immunology (Baltimore, Md. : 1950). PMID 31996456 DOI: 10.4049/Jimmunol.1900239  0.468
2020 Parikh KS, Doerfler S, Shelburne N, Kennedy K, Whitson J, Dahhan T, Fortin T, Rajagopal S. Experience in Transitioning from Parenteral Prostacyclins to Selexipag in Pulmonary Arterial Hypertension. Journal of Cardiovascular Pharmacology. PMID 31934912 DOI: 10.1097/Fjc.0000000000000800  0.457
2020 Alenezi F, Rajagopal S, Kutty S. Assessing right atrial function in pulmonary hypertension: window to the soul of the right heart? American Journal of Physiology. Heart and Circulatory Physiology. 318: H154-H155. PMID 31858830 DOI: 10.1152/Ajpheart.00739.2019  0.445
2020 Zheng K, Smith JS, Choi I, Warman A, Gundry JN, Pack TF, Inoue A, Caron M, Rajagopal S. Biased agonists of the chemokine receptor CXCR3 differentially drive formation of Gαi and β‐arrestin complexes The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03543  0.622
2020 Lee CY, Decker AM, Xiong X, Viswanathan G, Kohlmann T, Smith JS, Inoue A, Namjoshi OA, Rajagopal S. ACKR3 Regulates Endothelial Cell Function with Non‐canonical Integration of Gαi and β‐arrestin The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03328  0.437
2020 Eiger DS, Smith J, Tsai C, Jacobs J, Shi T, Rajagopal S. Biased Agonism at CXCR3 Drives Differential Phosphoproteomic and Transcriptomic Profiles and Cellular Outputs The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.00292  0.435
2020 Arps K, Rajagopal S. Extra Volume: Pulmonary Hypertension Caused By Extra-Cardiac And Intra-Cardiac Shunting Journal of the American College of Cardiology. 75: 2804. DOI: 10.1016/S0735-1097(20)33431-8  0.441
2020 Suwanpradid J, Lee M, Hoang P, Kwock J, Floyd L, Smith J, Yin Z, Atwater A, Rajagopal S, Kedl R, Corcoran D, MacLeod AS. 014 IL-27 induces IL-15 production to facilitate T cell survival in allergic contact dermatitis Journal of Investigative Dermatology. 140. DOI: 10.1016/J.Jid.2020.03.016  0.389
2019 Narayanan S, Vasukuttan V, Rajagopal S, Maitra R, Runyon SP. Identification of potent pyrazole based APELIN receptor (APJ) agonists. Bioorganic & Medicinal Chemistry. 115237. PMID 31948845 DOI: 10.1016/J.Bmc.2019.115237  0.551
2019 Edmonston DL, Parikh KS, Rajagopal S, Shaw LK, Abraham D, Grabner A, Sparks MA, Wolf M. Pulmonary Hypertension Subtypes and Mortality in CKD. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. PMID 31732231 DOI: 10.1053/J.Ajkd.2019.08.027  0.439
2019 Wang Z, Bier EA, Swaminathan A, Parikh K, Nouls J, He M, Mammarappallil JG, Luo S, Driehuys B, Rajagopal S. Diverse Cardiopulmonary Diseases are Associated with Distinct Xenon MRI Signatures. The European Respiratory Journal. PMID 31619473 DOI: 10.1183/13993003.00831-2019  0.459
2019 Shelburne NJ, Parikh KS, Chiswell K, Shaw LK, Sivak J, Arges K, Tomfohr J, Velazquez EJ, Kisslo J, Samad Z, Rajagopal S. Echocardiographic Assessment of Right Ventricular Function and Response to Therapy in Pulmonary Arterial Hypertension. The American Journal of Cardiology. PMID 31481176 DOI: 10.1016/J.Amjcard.2019.07.026  0.439
2019 Antonia AL, Gibbs KD, Trahair ED, Pittman KJ, Martin AT, Schott BH, Smith JS, Rajagopal S, Thompson JW, Reinhardt RL, Ko DC. Pathogen Evasion of Chemokine Response Through Suppression of CXCL10. Frontiers in Cellular and Infection Microbiology. 9: 280. PMID 31440475 DOI: 10.3389/Fcimb.2019.00280  0.512
2019 Tsai CF, Smith J, Krajewski K, Zhao R, Moghieb AM, Nicora CD, Xiong X, Moore RJ, Liu T, Smith RD, Jacobs JM, Rajagopal S, Shi T. TMT labeling facilitates RPLC-MS analysis of hydrophilic phosphopeptides. Analytical Chemistry. PMID 31418558 DOI: 10.1021/Acs.Analchem.9B01814  0.475
2019 Mamazhakypov A, Viswanathan G, Lawrie A, Schermuly RT, Rajagopal S. The role of chemokines and chemokine receptors in pulmonary arterial hypertension. British Journal of Pharmacology. PMID 31399998 DOI: 10.1111/Bph.14826  0.547
2019 Benza RL, Doyle M, Lasorda D, Parikh KS, Correa-Jaque P, Badie N, Ginn G, Airhart S, Franco V, Kanwar M, Murali S, Raina A, Agarwal R, Rajagopal S, White J, et al. Monitoring Pulmonary Arterial Hypertension Using an Implantable Hemodynamic Sensor. Chest. PMID 31265832 DOI: 10.1016/J.Chest.2019.06.010  0.445
2019 Clapham KR, Singh I, Capuano IS, Rajagopal S, Chun HJ. MEF2 and the Right Ventricle: From Development to Disease. Frontiers in Cardiovascular Medicine. 6: 29. PMID 30984767 DOI: 10.3389/Fcvm.2019.00029  0.471
2019 Parikh KS, Dahhan T, Nicholl L, Ruopp N, Pomann GM, Fortin T, Tapson VF, Rajagopal S. Clinical Features and Outcomes of Patients with Sarcoidosis-associated Pulmonary Hypertension. Scientific Reports. 9: 4061. PMID 30858405 DOI: 10.1038/S41598-019-40030-W  0.46
2019 Suwanpradid J, Hoang P, Kwock J, Floyd L, Smith J, Kedl R, Atwater A, Rajagopal S, Corcoran D, MacLeod A. 010 IL-27 in macrophages mediates T cell survival and dermal cluster formation in allergic contact hypersensitivity Journal of Investigative Dermatology. 139: S2. DOI: 10.1016/J.Jid.2019.03.086  0.404
2018 Viswanathan G, Mamazhakypov A, Schermuly RT, Rajagopal S. The Role of G Protein-Coupled Receptors in the Right Ventricle in Pulmonary Hypertension. Frontiers in Cardiovascular Medicine. 5: 179. PMID 30619886 DOI: 10.3389/Fcvm.2018.00179  0.601
2018 Ma Z, Yu YR, Badea CT, Kovacs JJ, Xiong X, Comhair S, Piantadosi CA, Rajagopal S. Vascular Endothelial Growth Factor Receptor 3 Regulates Endothelial Function Through β-Arrestin 1. Circulation. PMID 30586762 DOI: 10.1161/Circulationaha.118.034961  0.789
2018 Alenezi F, Mandawat A, Il'Giovine ZJ, Shaw LK, Siddiqui I, Tapson VF, Arges K, Rivera D, Romano MMD, Velazquez EJ, Douglas PS, Samad Z, Rajagopal S. Clinical Utility and Prognostic Value of Right Atrial Function in Pulmonary Hypertension. Circulation. Cardiovascular Imaging. 11: e006984. PMID 30571314 DOI: 10.1161/Circimaging.117.006984  0.429
2018 Rajarathnam K, Schnoor M, Richardson RM, Rajagopal S. How do chemokines navigate neutrophils to the target site: Dissecting the structural mechanisms and signaling pathways. Cellular Signalling. PMID 30465827 DOI: 10.1016/J.Cellsig.2018.11.004  0.626
2018 Bier EA, Robertson SH, Schrank GM, Rackley C, Mammarappallil JG, Rajagopal S, McAdams HP, Driehuys B. A protocol for quantifying cardiogenic oscillations in dynamic Xe gas exchange spectroscopy: The effects of idiopathic pulmonary fibrosis. Nmr in Biomedicine. e4029. PMID 30457202 DOI: 10.1002/Nbm.4029  0.422
2018 Ghadimi K, Rajagopal S. Nasally Inhaled Nitric Oxide for Sudden Right-Sided Heart Failure in the Intensive Care Unit: NO Time Like the Present. Journal of Cardiothoracic and Vascular Anesthesia. PMID 30420312 DOI: 10.1053/J.Jvca.2018.10.008  0.404
2018 Smith JS, Nicholson LT, Suwanpradid J, Glenn RA, Knape NM, Alagesan P, Gundry JN, Wehrman TS, Atwater AR, Gunn MD, MacLeod AS, Rajagopal S. Biased agonists of the chemokine receptor CXCR3 differentially control chemotaxis and inflammation. Science Signaling. 11. PMID 30401786 DOI: 10.1126/Scisignal.Aaq1075  0.607
2018 Luttrell LM, Wang J, Plouffe B, Smith JS, Yamani L, Kaur S, Jean-Charles PY, Gauthier C, Lee MH, Pani B, Kim J, Ahn S, Rajagopal S, Reiter E, Bouvier M, et al. Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9. Science Signaling. 11. PMID 30254056 DOI: 10.1126/Scisignal.Aat7650  0.797
2018 Siddiqui I, Rajagopal S, Brucker A, Chiswell K, Christopher B, Alenezi F, Mandawat A, Rivera D, Arges K, Tapson V, Kisslo J, Velazquez E, Douglas PS, Samad Z. Clinical and Echocardiographic Predictors of Outcomes in Patients With Pulmonary Hypertension. The American Journal of Cardiology. PMID 30093068 DOI: 10.1016/J.Amjcard.2018.05.019  0.436
2018 Wang Z, He M, Bier E, Rankine L, Schrank G, Rajagopal S, Huang YC, Kelsey C, Womack S, Mammarappallil J, Driehuys B. Hyperpolarized Xe gas transfer MRI: the transition from 1.5T to 3T. Magnetic Resonance in Medicine. PMID 30024058 DOI: 10.1002/Mrm.27377  0.411
2018 Loyalka P, Ansari MZ, Cheema FH, Miller CC, Rajagopal S, Rajagopal K. Surgical pulmonary embolectomy and catheter-based therapies for acute pulmonary embolism: A contemporary systematic review. The Journal of Thoracic and Cardiovascular Surgery. PMID 30005883 DOI: 10.1016/J.Jtcvs.2018.05.085  0.626
2018 Smith JS, Rajagopal S, Atwater AR. Chemokine Signaling in Allergic Contact Dermatitis: Toward Targeted Therapies. Dermatitis : Contact, Atopic, Occupational, Drug. PMID 29939854 DOI: 10.1097/Der.0000000000000391  0.584
2018 Il'Giovine ZJ, Mulder H, Chiswell K, Arges K, Tomfohr J, Hashmi A, Velazquez EJ, Kisslo JA, Samad Z, Rajagopal S. Right Ventricular Longitudinal Strain Reproducibility Using Vendor-Dependent and Vendor-Independent Software. Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. PMID 29525250 DOI: 10.1016/J.Echo.2018.01.008  0.434
2018 Smith JS, Lefkowitz RJ, Rajagopal S. Biased signalling: from simple switches to allosteric microprocessors. Nature Reviews. Drug Discovery. PMID 29302067 DOI: 10.1038/Nrd.2017.229  0.694
2017 Luo N, Craig D, Ilkayeva O, Muehlbauer M, Kraus WE, Newgard CB, Shah SH, Rajagopal S. Plasma acylcarnitines are associated with pulmonary hypertension. Pulmonary Circulation. 7: 211-218. PMID 28680580 DOI: 10.1086/690554  0.42
2017 Parikh KS, Rao Y, Ahmad T, Shen K, Felker GM, Rajagopal S. Novel approach to classifying patients with pulmonary arterial hypertension using cluster analysis. Pulmonary Circulation. 7: 486-493. PMID 28597780 DOI: 10.1177/2045893217705891  0.411
2017 Smith JS, Alagesan P, Desai NK, Pack TF, Wu JH, Inoue A, Freedman NJ, Rajagopal S. C-X-C Motif Chemokine Receptor 3 Splice Variants Differentially Activate Beta-Arrestins to Regulate Downstream Signaling Pathways. Molecular Pharmacology. PMID 28559424 DOI: 10.1124/Mol.117.108522  0.769
2017 Wang Z, Robertson SH, Wang J, He M, Virgincar RS, Schrank GM, Bier EA, Rajagopal S, Huang YC, O'Riordan TG, Rackley CR, McAdams HP, Driehuys B. Quantitative Analysis of Hyperpolarized (129) Xe Gas Transfer MRI. Medical Physics. PMID 28382694 DOI: 10.1002/Mp.12264  0.421
2017 Broderick-Forsgren K, Davenport CA, Sivak JA, Hargett CW, Foster MC, Monteagudo A, Armour A, Rajagopal S, Arges K, Velazquez EJ, Samad Z. Improving on the diagnostic characteristics of echocardiography for pulmonary hypertension. The International Journal of Cardiovascular Imaging. PMID 28337558 DOI: 10.1007/S10554-017-1114-2  0.439
2017 Onaran HO, Ambrosio C, Uğur Ö, Madaras Koncz E, Grò MC, Vezzi V, Rajagopal S, Costa T. Systematic errors in detecting biased agonism: Analysis of current methods and development of a new model-free approach. Scientific Reports. 7: 44247. PMID 28290478 DOI: 10.1038/Srep44247  0.563
2017 Dahhan T, Alenezi F, Samad Z, Rajagopal S. Echocardiography in the Risk Assessment of Acute Pulmonary Embolism. Seminars in Respiratory and Critical Care Medicine. 38: 18-28. PMID 28208195 DOI: 10.1055/S-0036-1597563  0.436
2017 Gundry J, Glenn R, Alagesan P, Rajagopal S. A Practical Guide to Approaching Biased Agonism at G Protein Coupled Receptors. Frontiers in Neuroscience. 11: 17. PMID 28174517 DOI: 10.3389/Fnins.2017.00017  0.609
2017 Rajagopal S, Shenoy SK. GPCR desensitization: Acute and prolonged phases. Cellular Signalling. PMID 28137506 DOI: 10.1016/J.Cellsig.2017.01.024  0.77
2017 Smith J, Nicholson L, Suwanpradid J, Glenn R, Gundry J, Alagesan P, Knape N, Atwater A, Gunn M, MacLeod A, Lefkowitz R, Rajagopal S. 678 Biased CXCR3 ligands differentially alter allergic contact hypersensitivity and chemotaxis Journal of Investigative Dermatology. 137: S117. DOI: 10.1016/J.Jid.2017.02.701  0.55
2016 Dahhan T, Siddiqui I, Tapson VF, Velazquez EJ, Sun S, Davenport CA, Samad Z, Rajagopal S. Clinical and echocardiographic predictors of mortality in acute pulmonary embolism. Cardiovascular Ultrasound. 14: 44. PMID 27793158 DOI: 10.1186/S12947-016-0087-Y  0.435
2016 Ma Z, Mao L, Rajagopal S. Hemodynamic Characterization of Rodent Models of Pulmonary Arterial Hypertension. Journal of Visualized Experiments : Jove. PMID 27167679 DOI: 10.3791/53335  0.455
2016 Dahhan T, Kaushik SS, He M, Mammarappallil JG, Tapson VF, McAdams HP, Sporn TA, Driehuys B, Rajagopal S. Abnormalities in hyperpolarized (129)Xe magnetic resonance imaging and spectroscopy in two patients with pulmonary vascular disease. Pulmonary Circulation. 6: 126-31. PMID 27162620 DOI: 10.1086/685110  0.435
2016 Smith JS, Rajagopal S. The β-arrestins: Multifunctional regulators of G protein-coupled receptors. The Journal of Biological Chemistry. PMID 26984408 DOI: 10.1074/Jbc.R115.713313  0.617
2016 Parikh KS, Rajagopal S, Fortin T, Tapson VF, Poms AD. Safety and Tolerability of High-dose Inhaled Treprostinil in Pulmonary Hypertension. Journal of Cardiovascular Pharmacology. PMID 26828324 DOI: 10.1097/Fjc.0000000000000357  0.443
2015 Forsha D, Risum N, Rajagopal S, Dolgner S, Hornik C, Barnhart H, Kisslo J, Barker P. The influence of angle of insonation and target depth on speckle-tracking strain. Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. 28: 580-6. PMID 25655402 DOI: 10.1016/J.Echo.2014.12.015  0.4
2015 Parikh KS, Rajagopal S, Arges K, Ahmad T, Sivak J, Kaul P, Shah SH, Tapson V, Velazquez EJ, Douglas PS, Samad Z. Use of outcome measures in pulmonary hypertension clinical trials American Heart Journal. DOI: 10.1016/j.ahj.2015.06.010  0.424
2014 Onaran HO, Rajagopal S, Costa T. What is biased efficacy? Defining the relationship between intrinsic efficacy and free energy coupling. Trends in Pharmacological Sciences. 35: 639-47. PMID 25448316 DOI: 10.1016/J.Tips.2014.09.010  0.59
2014 Kahsai AW, Rajagopal S, Sun J, Xiao K. Monitoring protein conformational changes and dynamics using stable-isotope labeling and mass spectrometry. Nature Protocols. 9: 1301-19. PMID 24810039 DOI: 10.1038/Nprot.2014.075  0.647
2014 Rajagopal S, Forsha DE, Risum N, Hornik CP, Poms AD, Fortin TA, Tapson VF, Velazquez EJ, Kisslo J, Samad Z. Comprehensive assessment of right ventricular function in patients with pulmonary hypertension with global longitudinal peak systolic strain derived from multiple right ventricular views. Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. 27: 657-665.e3. PMID 24656881 DOI: 10.1016/J.Echo.2014.02.001  0.449
2014 Forsha D, Risum N, Kropf PA, Rajagopal S, Smith PB, Kanter RJ, Samad Z, Sogaard P, Barker P, Kisslo J. Right ventricular mechanics using a novel comprehensive three-view echocardiographic strain analysis in a normal population. Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. 27: 413-22. PMID 24508364 DOI: 10.1016/J.Echo.2013.12.018  0.421
2014 Rajagopal S, Bassoni D, Campbell J, Gerard N, Gerard C, Wehrman T. Understanding the mechanism of biased agonism at chemokine receptors (1066.17) The Faseb Journal. 28. DOI: 10.1096/Fasebj.28.1_Supplement.1066.17  0.613
2014 Krishnamoorthy A, Vakamudi S, Watson MH, Byrns JS, Rajagopal S, Felker GM, Rogers JG, Patel CB. Hemodynamic Response to Continuous Outpatient Milrinone Infusion in Advanced Heart Failure Patients with Mixed Pulmonary Hypertension Journal of Cardiac Failure. 20. DOI: 10.1016/J.Cardfail.2014.06.118  0.438
2013 Rajagopal S, Bassoni DL, Campbell JJ, Gerard NP, Gerard C, Wehrman TS. Biased agonism as a mechanism for differential signaling by chemokine receptors. The Journal of Biological Chemistry. 288: 35039-48. PMID 24145037 DOI: 10.1074/Jbc.M113.479113  0.641
2013 Rajagopal S. Quantifying biased agonism: understanding the links between affinity and efficacy. Nature Reviews. Drug Discovery. 12: 483. PMID 23681006 DOI: 10.1038/Nrd3954-C1  0.429
2012 Xiao K, Sun J, Kim J, Rajagopal S, Zhai B, Villén J, Haas W, Kovacs JJ, Shukla AK, Hara MR, Hernandez M, Lachmann A, Zhao S, Lin Y, Cheng Y, et al. Global phosphorylation analysis of β-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR) (Proceedings of the National Academy of Sciences of the United States of America (2010) 107, 34 (15299-15304) doi:10.1073/pnas.1008461107) Proceedings of the National Academy of Sciences of the United States of America. 109: 13464. DOI: 10.1073/Pnas.1211889109  0.774
2011 Nobles KN, Xiao K, Ahn S, Shukla AK, Lam CM, Rajagopal S, Strachan RT, Huang TY, Bressler EA, Hara MR, Shenoy SK, Gygi SP, Lefkowitz RJ. Distinct phosphorylation sites on the β(2)-adrenergic receptor establish a barcode that encodes differential functions of β-arrestin. Science Signaling. 4: ra51. PMID 21868357 DOI: 10.1126/Scisignal.2001707  0.734
2011 Hara MR, Kovacs JJ, Whalen EJ, Rajagopal S, Strachan RT, Grant W, Towers AJ, Williams B, Lam CM, Xiao K, Shenoy SK, Gregory SG, Ahn S, Duckett DR, Lefkowitz RJ. A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1. Nature. 477: 349-53. PMID 21857681 DOI: 10.1038/Nature10368  0.733
2011 Kahsai AW, Xiao K, Rajagopal S, Ahn S, Shukla AK, Sun J, Oas TG, Lefkowitz RJ. Multiple ligand-specific conformations of the β2-adrenergic receptor. Nature Chemical Biology. 7: 692-700. PMID 21857662 DOI: 10.1038/Nchembio.634  0.809
2011 Rajagopal S, Ahn S, Rominger DH, Gowen-MacDonald W, Lam CM, Dewire SM, Violin JD, Lefkowitz RJ. Quantifying ligand bias at seven-transmembrane receptors. Molecular Pharmacology. 80: 367-77. PMID 21610196 DOI: 10.1124/Mol.111.072801  0.803
2011 Whalen EJ, Rajagopal S, Lefkowitz RJ. Therapeutic potential of β-arrestin- and G protein-biased agonists. Trends in Molecular Medicine. 17: 126-39. PMID 21183406 DOI: 10.1016/J.Molmed.2010.11.004  0.794
2011 Rajagopal S, Kovacs J, Badea C, Johnson GA, Rockman HA, Piantadosi CA, Lefkowitz RJ. BETA-ARRESTINS REGULATE SIGNALING BY BONE MORPHOGENETIC PROTEIN TYPE II RECEPTOR IN PULMONARY ARTERIAL HYPERTENSION Journal of the American College of Cardiology. 57: E2046. DOI: 10.1016/S0735-1097(11)62046-9  0.628
2010 Xiao K, Sun J, Kim J, Rajagopal S, Zhai B, Villén J, Haas W, Kovacs JJ, Shukla AK, Hara MR, Hernandez M, Lachmann A, Zhao S, Lin Y, Cheng Y, et al. Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR). Proceedings of the National Academy of Sciences of the United States of America. 107: 15299-304. PMID 20686112 DOI: 10.1073/Pnas.1008461107  0.78
2010 Rajagopal S, Rajagopal K, Lefkowitz RJ. Teaching old receptors new tricks: biasing seven-transmembrane receptors. Nature Reviews. Drug Discovery. 9: 373-86. PMID 20431569 DOI: 10.1038/Nrd3024  0.783
2010 Rajagopal S, Kim J, Ahn S, Craig S, Lam CM, Gerard NP, Gerard C, Lefkowitz RJ. Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7. Proceedings of the National Academy of Sciences of the United States of America. 107: 628-32. PMID 20018651 DOI: 10.1073/Pnas.0912852107  0.753
2007 Rajagopal S, Kent SB. Total chemical synthesis and biophysical characterization of the minimal isoform of the KChIP2 potassium channel regulatory subunit. Protein Science : a Publication of the Protein Society. 16: 2056-64. PMID 17660260 DOI: 10.1110/Ps.072876107  0.427
2005 Ihee H, Rajagopal S, Srajer V, Pahl R, Anderson S, Schmidt M, Schotte F, Anfinrud PA, Wulff M, Moffat K. Visualizing reaction pathways in photoactive yellow protein from nanoseconds to seconds. Proceedings of the National Academy of Sciences of the United States of America. 102: 7145-50. PMID 15870207 DOI: 10.1073/Pnas.0409035102  0.487
2005 Rajagopal S, Anderson S, Srajer V, Schmidt M, Pahl R, Moffat K. A structural pathway for signaling in the E46Q mutant of photoactive yellow protein. Structure (London, England : 1993). 13: 55-63. PMID 15642261 DOI: 10.1016/J.Str.2004.10.016  0.513
2005 Moffat K, Anderson S, Rajagopal S, Srajer V, Pahl R, Ihee H, Schmidt M, Key J. How do signaling photoreceptors respond to light? Acta Crystallographica Section a Foundations of Crystallography. 61: c72-c72. DOI: 10.1107/S0108767305096947  0.462
2004 Rajagopal S, Key JM, Purcell EB, Boerema DJ, Moffat K. Purification and initial characterization of a putative blue light-regulated phosphodiesterase from Escherichia coli. Photochemistry and Photobiology. 80: 542-7. PMID 15453820 DOI: 10.1562/0031-8655(2004)080<0542:Paicoa>2.0.Co;2  0.461
2004 Rajagopal S, Kostov KS, Moffat K. Analytical trapping: extraction of time-independent structures from time-dependent crystallographic data. Journal of Structural Biology. 147: 211-22. PMID 15450291 DOI: 10.1016/J.Jsb.2004.04.007  0.436
2004 Anderson S, Srajer V, Pahl R, Rajagopal S, Schotte F, Anfinrud P, Wulff M, Moffat K. Chromophore conformation and the evolution of tertiary structural changes in photoactive yellow protein. Structure (London, England : 1993). 12: 1039-45. PMID 15274923 DOI: 10.1016/J.Str.2004.04.008  0.47
2004 Rajagopal S, Schmidt M, Anderson S, Ihee H, Moffat K. Analysis of experimental time-resolved crystallographic data by singular value decomposition. Acta Crystallographica. Section D, Biological Crystallography. 60: 860-71. PMID 15103131 DOI: 10.1107/S0907444904004160  0.447
2004 Schmidt M, Pahl R, Srajer V, Anderson S, Ren Z, Ihee H, Rajagopal S, Moffat K. Protein kinetics: structures of intermediates and reaction mechanism from time-resolved x-ray data. Proceedings of the National Academy of Sciences of the United States of America. 101: 4799-804. PMID 15041745 DOI: 10.1073/Pnas.0305983101  0.436
2004 Schmidt M, Rajagopal S, Anderson S, Moffat K. Protein kinetics: relaxations on atomic length scales Acta Crystallographica Section a Foundations of Crystallography. 60: s19-s19. DOI: 10.1107/S0108767304099647  0.419
2003 Schmidt M, Rajagopal S, Ren Z, Moffat K. Application of singular value decomposition to the analysis of time-resolved macromolecular x-ray data. Biophysical Journal. 84: 2112-29. PMID 12609912 DOI: 10.1016/S0006-3495(03)75018-8  0.447
2003 Rajagopal S, Moffat K. Crystal structure of a photoactive yellow protein from a sensor histidine kinase: conformational variability and signal transduction. Proceedings of the National Academy of Sciences of the United States of America. 100: 1649-54. PMID 12563032 DOI: 10.1073/Pnas.0336353100  0.52
2003 Crosson S, Rajagopal S, Moffat K. The LOV domain family: photoresponsive signaling modules coupled to diverse output domains. Biochemistry. 42: 2-10. PMID 12515534 DOI: 10.1021/Bi026978L  0.445
2002 Schmidt M, Pahl R, Srajer V, Anderson S, Brister K, Ruan S, Rajagopal S, Ren Z, Moffat K. Application of singular value decomposition to time-resolved X-ray data; simulations and experiments Acta Crystallographica Section a Foundations of Crystallography. 58: c374-c374. DOI: 10.1107/S0108767302099956  0.382
2002 Moffat K, Srajer V, Pahl R, Ren Z, Schmidt M, Anderson S, Crosson S, Perman B, Rajagopal S, Ihee H, Bourgeois D, Wulff M. Time-resolved macromolecular crystallography: molecular movies? Acta Crystallographica Section a Foundations of Crystallography. 58: c27-c27. DOI: 10.1107/S0108767302086166  0.397
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