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Alex Thomsen - Publications

Affiliations: 
Duke University, Durham, NC 
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21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Peach CJ, Tonello R, Gomez K, Calderon-Rivera A, Sánchez MR, Maile L, Perez-Miller S, Manu AM, Hahn H, Thomsen ARB, Schmidt BL, Davidson S, Khanna M, Khanna R, Bunnett NW. Neuropilin-1 is a co-receptor for NGF and TrkA-evoked pain. Biorxiv : the Preprint Server For Biology. PMID 38106002 DOI: 10.1101/2023.12.06.570398  0.3
2023 Daly C, Guseinov AA, Hahn H, Wright A, Tikhonova IG, Thomsen ARB, Plouffe B. β-Arrestin-dependent and -independent endosomal G protein activation by the vasopressin type 2 receptor. Elife. 12. PMID 37855711 DOI: 10.7554/eLife.87754  0.71
2023 Thomsen ARB. GPCRs and β-arrestins - an on-off relationship. Cell Research. PMID 37337029 DOI: 10.1038/s41422-023-00838-8  0.428
2023 Hegron A, Peach CJ, Tonello R, Seemann P, Teng S, Latorre R, Huebner H, Weikert D, Rientjes J, Veldhuis NA, Poole DP, Jensen DD, Thomsen ARB, Schmidt BL, Imlach WL, et al. Therapeutic antagonism of the neurokinin 1 receptor in endosomes provides sustained pain relief. Proceedings of the National Academy of Sciences of the United States of America. 120: e2220979120. PMID 37216510 DOI: 10.1073/pnas.2220979120  0.403
2023 Daly C, Guseinov AA, Hahn H, Tikhonova IG, Thomsen ARB, Plouffe B. β-arrestin-dependent and -independent endosomal G protein activation by the vasopressin type 2 receptor. Biorxiv : the Preprint Server For Biology. PMID 37034816 DOI: 10.1101/2023.04.01.535208  0.603
2020 Plouffe B, Thomsen ARB, Irannejad R. Emerging Role of Compartmentalized G Protein-Coupled Receptor Signaling in the Cardiovascular Field. Acs Pharmacology & Translational Science. 3: 221-236. PMID 32296764 DOI: 10.1021/acsptsci.0c00006  0.663
2019 Nguyen AH, Thomsen ARB, Cahill TJ, Huang R, Huang LY, Marcink T, Clarke OB, Heissel S, Masoudi A, Ben-Hail D, Samaan F, Dandey VP, Tan YZ, Hong C, Mahoney JP, et al. Structure of an endosomal signaling GPCR-G protein-β-arrestin megacomplex. Nature Structural & Molecular Biology. PMID 31740855 DOI: 10.1038/S41594-019-0330-Y  0.732
2018 Thomsen ARB, Jensen DD, Hicks GA, Bunnett NW. Therapeutic Targeting of Endosomal G-Protein-Coupled Receptors. Trends in Pharmacological Sciences. PMID 30180973 DOI: 10.1016/J.Tips.2018.08.003  0.626
2018 Zhang DL, Sun YJ, Ma ML, Wang YJ, Lin H, Li RR, Liang ZL, Gao Y, Yang Z, He DF, Lin A, Mo H, Lu YJ, Li MJ, Kong W, ... ... Thomsen ARB, et al. Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility. Elife. 7. PMID 29393851 DOI: 10.7554/Elife.33432  0.69
2018 Zhang D, Sun Y, Ma M, Wang Y, Lin H, Li R, Liang Z, Gao Y, Yang Z, He D, Lin A, Mo H, Lu Y, Li M, Kong W, ... ... Thomsen ARB, et al. Author response: Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility Elife. DOI: 10.7554/Elife.33432.051  0.556
2017 Cahill TJ, Thomsen AR, Tarrasch JT, Plouffe B, Nguyen AH, Yang F, Huang LY, Kahsai AW, Bassoni DL, Gavino BJ, Lamerdin JE, Triest S, Shukla AK, Berger B, Little J, et al. Distinct conformations of GPCR-β-arrestin complexes mediate desensitization, signaling, and endocytosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 28223524 DOI: 10.1073/Pnas.1701529114  0.772
2017 Liu CH, Gong Z, Liang ZL, Liu ZX, Yang F, Sun YJ, Ma ML, Wang YJ, Ji CR, Wang YH, Wang MJ, Cui FA, Lin A, Zheng WS, He DF, ... ... Thomsen AR, et al. Arrestin-biased AT1R agonism induces acute catecholamine secretion through TRPC3 coupling. Nature Communications. 8: 14335. PMID 28181498 DOI: 10.1038/Ncomms14335  0.718
2017 Cahill T, Thomsen A, Plouffe B, Bouvier M, Lefkowitz R. LB987 New insights into gpcr-transducer coupling Journal of Investigative Dermatology. 137: B10. DOI: 10.1016/J.Jid.2017.07.067  0.572
2016 Thomsen AR, Plouffe B, Cahill TJ, Shukla AK, Tarrasch JT, Dosey AM, Kahsai AW, Strachan RT, Pani B, Mahoney JP, Huang L, Breton B, Heydenreich FM, Sunahara RK, Skiniotis G, et al. GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling. Cell. PMID 27499021 DOI: 10.1016/J.Cell.2016.07.004  0.691
2016 Kahsai AW, Wisler JW, Lee J, Ahn S, Cahill Iii TJ, Dennison SM, Staus DP, Thomsen AR, Anasti KM, Pani B, Wingler LM, Desai H, Bompiani KM, Strachan RT, Qin X, et al. Conformationally selective RNA aptamers allosterically modulate the β2-adrenoceptor. Nature Chemical Biology. PMID 27398998 DOI: 10.1038/Nchembio.2126  0.615
2014 Wisler JW, Xiao K, Thomsen AR, Lefkowitz RJ. Recent developments in biased agonism. Current Opinion in Cell Biology. 27: 18-24. PMID 24680426 DOI: 10.1016/J.Ceb.2013.10.008  0.647
2014 Nørskov-Lauritsen L, Thomsen AR, Bräuner-Osborne H. G protein-coupled receptor signaling analysis using homogenous time-resolved Förster resonance energy transfer (HTRF®) technology. International Journal of Molecular Sciences. 15: 2554-72. PMID 24531140 DOI: 10.3390/ijms15022554  0.408
2013 Jacobsen SE, Nørskov-Lauritsen L, Thomsen AR, Smajilovic S, Wellendorph P, Larsson NH, Lehmann A, Bhatia VK, Bräuner-Osborne H. Delineation of the GPRC6A receptor signaling pathways using a mammalian cell line stably expressing the receptor. The Journal of Pharmacology and Experimental Therapeutics. 347: 298-309. PMID 24008333 DOI: 10.1124/Jpet.113.206276  0.581
2012 Thomsen AR, Worm J, Jacobsen SE, Stahlhut M, Latta M, Bräuner-Osborne H. Strontium is a biased agonist of the calcium-sensing receptor in rat medullary thyroid carcinoma 6-23 cells. The Journal of Pharmacology and Experimental Therapeutics. 343: 638-49. PMID 22942242 DOI: 10.1124/jpet.112.197210  0.304
2012 Thomsen AR, Hvidtfeldt M, Bräuner-Osborne H. Biased agonism of the calcium-sensing receptor. Cell Calcium. 51: 107-16. PMID 22192592 DOI: 10.1016/j.ceca.2011.11.009  0.575
2011 Gloriam DE, Wellendorph P, Johansen LD, Thomsen AR, Phonekeo K, Pedersen DS, Bräuner-Osborne H. Chemogenomic discovery of allosteric antagonists at the GPRC6A receptor. Chemistry & Biology. 18: 1489-98. PMID 22118683 DOI: 10.1016/J.Chembiol.2011.09.012  0.457
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