| Year |
Citation |
Score |
| 2024 |
Shen Y, Dinh HV, Cruz ER, Chen Z, Bartman CR, Xiao T, Call CM, Ryseck RP, Pratas J, Weilandt D, Baron H, Subramanian A, Fatma Z, Wu ZY, Dwaraknath S, ... ... Yang L, et al. Mitochondrial ATP generation is more proteome efficient than glycolysis. Nature Chemical Biology. PMID 38448734 DOI: 10.1038/s41589-024-01571-y |
0.562 |
|
| 2024 |
Cherkaoui S, Yang L, McBride M, Turn CS, Lu W, Eigenmann C, Allen GE, Panasenko OO, Zhang L, Vu A, Liu K, Li Y, Gandhi OH, Surrey L, Wierer M, et al. Reprogramming neuroblastoma by diet-enhanced polyamine depletion. Biorxiv : the Preprint Server For Biology. PMID 38260457 DOI: 10.1101/2024.01.07.573662 |
0.583 |
|
| 2023 |
Kutschka I, Bertero E, Wasmus C, Xiao K, Yang L, Chen X, Oshima Y, Fischer M, Erk M, Arslan B, Alhasan L, Grosser D, Ermer KJ, Nickel A, Kohlhaas M, et al. Activation of the integrated stress response rewires cardiac metabolism in Barth syndrome. Basic Research in Cardiology. 118: 47. PMID 37930434 DOI: 10.1007/s00395-023-01017-x |
0.522 |
|
| 2023 |
Bartman CR, Weilandt DR, Shen Y, Lee WD, Han Y, TeSlaa T, Jankowski CSR, Samarah L, Park NR, da Silva-Diz V, Aleksandrova M, Gultekin Y, Marishta A, Wang L, Yang L, et al. Slow TCA flux and ATP production in primary solid tumours but not metastases. Nature. PMID 36725930 DOI: 10.1038/s41586-022-05661-6 |
0.564 |
|
| 2022 |
Zhao H, Teng D, Yang L, Xu X, Chen J, Jiang T, Feng AY, Zhang Y, Frederick DT, Gu L, Cai L, Asara JM, Pasca di Magliano M, Boland GM, Flaherty KT, et al. Myeloid-derived itaconate suppresses cytotoxic CD8 T cells and promotes tumour growth. Nature Metabolism. PMID 36376563 DOI: 10.1038/s42255-022-00676-9 |
0.605 |
|
| 2022 |
Yang L, TeSlaa T, Ng S, Nofal M, Wang L, Lan T, Zeng X, Cowan A, McBride M, Lu W, Davidson S, Liang G, Oh TG, Downes M, Evans R, et al. Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth. Med (New York, N.Y.). 3: 119-136. PMID 35425930 DOI: 10.1016/j.medj.2021.12.008 |
0.802 |
|
| 2022 |
Wang L, Xing X, Zeng X, Jackson SR, TeSlaa T, Al-Dalahmah O, Samarah LZ, Goodwin K, Yang L, McReynolds MR, Li X, Wolff JJ, Rabinowitz JD, Davidson SM. Spatially resolved isotope tracing reveals tissue metabolic activity. Nature Methods. 19: 223-230. PMID 35132243 DOI: 10.1038/s41592-021-01378-y |
0.765 |
|
| 2021 |
Zhang Z, TeSlaa T, Xu X, Zeng X, Yang L, Xing G, Tesz GJ, Clasquin MF, Rabinowitz JD. Serine catabolism generates liver NADPH and supports hepatic lipogenesis. Nature Metabolism. PMID 34845393 DOI: 10.1038/s42255-021-00487-4 |
0.731 |
|
| 2021 |
Ghergurovich JM, Xu X, Wang JZ, Yang L, Ryseck RP, Wang L, Rabinowitz JD. Methionine synthase supports tumour tetrahydrofolate pools. Nature Metabolism. 3: 1512-1520. PMID 34799699 DOI: 10.1038/s42255-021-00465-w |
0.515 |
|
| 2021 |
Nofal M, Wang T, Yang L, Jankowski CSR, Hsin-Jung Li S, Han S, Parsons L, Frese AN, Gitai Z, Anthony TG, Wühr M, Sabatini DM, Rabinowitz JD. GCN2 adapts protein synthesis to scavenging-dependent growth. Cell Systems. PMID 34706266 DOI: 10.1016/j.cels.2021.09.014 |
0.512 |
|
| 2021 |
Phan T, Nguyen VH, Buettner R, Morales C, Yang L, Wong P, Tsai W, Salazar MD, Gil Z, Diamond DJ, Rabinowitz JD, Rosen S, Melstrom LG. Inhibition of pyrimidine synthesis augments Gemcitabine induced growth inhibition in an immunocompetent model of pancreatic cancer. International Journal of Biological Sciences. 17: 2240-2251. PMID 34239352 DOI: 10.7150/ijbs.60473 |
0.645 |
|
| 2020 |
Hui S, Cowan AJ, Zeng X, Yang L, TeSlaa T, Li X, Bartman C, Zhang Z, Jang C, Wang L, Lu W, Rojas J, Baur J, Rabinowitz JD. Quantitative Fluxomics of Circulating Metabolites. Cell Metabolism. PMID 32791100 DOI: 10.1016/J.Cmet.2020.07.013 |
0.782 |
|
| 2020 |
Yang L, Garcia Canaveras JC, Chen Z, Wang L, Liang L, Jang C, Mayr JA, Zhang Z, Ghergurovich JM, Zhan L, Joshi S, Hu Z, McReynolds MR, Su X, White E, et al. Serine Catabolism Feeds NADH when Respiration Is Impaired. Cell Metabolism. PMID 32187526 DOI: 10.1016/J.Cmet.2020.02.017 |
0.569 |
|
| 2019 |
Bhagat TD, Von Ahrens D, Dawlaty M, Zou Y, Baddour J, Achreja A, Zhao H, Yang L, Patel B, Kang C, Choudhary G, Gordon-Mitchell S, Aluri S, Bhattacharyya S, Sahu S, et al. Lactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts. Elife. 8. PMID 31663852 DOI: 10.7554/Elife.50663 |
0.748 |
|
| 2019 |
Propper D, Han H, Hoff DV, Borazanci E, Reya T, Ghergurovich J, Pshenichnaya I, Antal C, Condjella R, Sharma S, O'Dwyer P, Littlewood T, Patel H, Saluja A, Velagapudi M, ... Yang L, et al. Abstract CT165: Phase II open label trial of minnelide™ in patients with chemotherapy refractory metastatic pancreatic cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Am2019-Ct165 |
0.454 |
|
| 2018 |
Wang L, Xing X, Chen L, Yang L, Su X, Rabitz HA, Lu W, Rabinowitz JD. Peak annotation and verification engine (PAVE) for untargeted LC-MS metabolomics. Analytical Chemistry. PMID 30586294 DOI: 10.1021/Acs.Analchem.8B03132 |
0.489 |
|
| 2017 |
Yang L, Venneti S, Nagrath D. Glutaminolysis: A Hallmark of Cancer Metabolism. Annual Review of Biomedical Engineering. PMID 28301735 DOI: 10.1146/Annurev-Bioeng-071516-044546 |
0.764 |
|
| 2017 |
Ju HQ, Ying H, Tian T, Ling J, Fu J, Lu Y, Wu M, Yang L, Achreja A, Chen G, Zhuang Z, Wang H, Nagrath D, Yao J, Hung MC, et al. Mutant Kras- and p16-regulated NOX4 activation overcomes metabolic checkpoints in development of pancreatic ductal adenocarcinoma. Nature Communications. 8: 14437. PMID 28232723 DOI: 10.1038/Ncomms14437 |
0.618 |
|
| 2017 |
Dey P, Baddour J, Muller F, Wu CC, Wang H, Liao WT, Lan Z, Chen A, Gutschner T, Kang Y, Fleming J, Satani N, Zhao D, Achreja A, Yang L, et al. Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer. Nature. PMID 28099419 DOI: 10.1038/Nature21052 |
0.688 |
|
| 2017 |
Achreja A, Zhao H, Yang L, Yun TH, Marini J, Nagrath D. Exo-MFA - A 13C metabolic flux analysis to dissect tumor microenvironment-secreted exosome contributions towards cancer cell metabolism. Metabolic Engineering. PMID 28087332 DOI: 10.1016/J.Ymben.2017.01.001 |
0.806 |
|
| 2016 |
Han C, Yang L, Choi HH, Baddour J, Achreja A, Liu Y, Li Y, Li J, Wan G, Huang C, Ji G, Zhang X, Nagrath D, Lu X. Amplification of USP13 drives ovarian cancer metabolism. Nature Communications. 7: 13525. PMID 27892457 DOI: 10.1038/Ncomms13525 |
0.754 |
|
| 2016 |
Yang L, Achreja A, Yeung TL, Mangala LS, Jiang D, Han C, Baddour J, Marini JC, Ni J, Nakahara R, Wahlig S, Chiba L, Kim SH, Morse J, Pradeep S, et al. Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth. Cell Metabolism. 24: 685-700. PMID 27829138 DOI: 10.1016/J.Cmet.2016.10.011 |
0.744 |
|
| 2016 |
Yang L. BH3 Mimetic ABT-737 Sensitizes Colorectal Cancer Cells to Ixazomib Through MCL-1 Downregulation and Autophagy Inhibition. International Journal of Radiation Oncology, Biology, Physics. 96: E559. PMID 27675012 DOI: 10.1016/j.ijrobp.2016.06.2028 |
0.36 |
|
| 2016 |
Yang L, Wan J, Xiao S, Barkhouse D, Zhu J, Li G, Lu B, Zhang Z. BH3 mimetic ABT-737 sensitizes colorectal cancer cells to ixazomib through MCL-1 downregulation and autophagy inhibition. American Journal of Cancer Research. 6: 1345-1357. PMID 27429848 |
0.373 |
|
| 2016 |
Zhao H, Yang L, Baddour J, Achreja A, Bernard V, Moss T, Marini J, Tudawe T, Seviour EG, San Lucas FA, Alvarez H, Gupta S, Maiti SN, Cooper L, Peehl D, et al. Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism. Elife. 5. PMID 26920219 DOI: 10.7554/Elife.10250 |
0.812 |
|
| 2016 |
Zand B, Previs RA, Zacharias NM, Rupaimoole R, Mitamura T, Nagaraja AS, Guindani M, Dalton HJ, Yang L, Baddour J, Achreja A, Hu W, Pecot CV, Ivan C, Wu SY, et al. Role of Increased n-acetylaspartate Levels in Cancer. Journal of the National Cancer Institute. 108. PMID 26819345 DOI: 10.1093/Jnci/Djv426 |
0.715 |
|
| 2015 |
Mondal S, Roy D, Camacho-Pereira J, Khurana A, Chini E, Yang L, Baddour J, Stilles K, Padmabandu S, Leung S, Kalloger S, Gilks B, Lowe V, Dierks T, Hammond E, et al. HSulf-1 deficiency dictates a metabolic reprograming of glycolysis and TCA cycle in ovarian cancer. Oncotarget. 6: 33705-19. PMID 26378042 DOI: 10.18632/Oncotarget.5605 |
0.718 |
|
| 2015 |
Nicolaou KC, Nilewski C, Hale CR, Ahles CF, Chiu CA, Ebner C, ElMarrouni A, Yang L, Stiles K, Nagrath D. Synthesis and biological evaluation of dimeric furanoid macroheterocycles: discovery of new anticancer agents. Journal of the American Chemical Society. 137: 4766-70. PMID 25827338 DOI: 10.1021/Jacs.5B00141 |
0.64 |
|
| 2015 |
Zhao H, Yang L, Baddour J, Achreja A, Bernard V, Moss T, Marini JC, Tudawe T, Seviour EG, Lucas FAS, Alvarez H, Gupta S, Maiti SN, Cooper L, Peehl D, et al. Author response: Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism Elife. DOI: 10.7554/Elife.10250.022 |
0.777 |
|
| 2015 |
Baddour J, Yang L, Achreja A, Padmabandu S, Shah P, Curtis RN, Plackemeier T, Khalid R, Marini JC, Franco-Barraza J, Cukierman E, Hu C, Maitra A, Nagrath D. Abstract 2913: Transcriptional reprogramming of pancreatic stroma induces metabolic changes in pancreatic tumor cells Cancer Research. 75: 2913-2913. DOI: 10.1158/1538-7445.Am2015-2913 |
0.67 |
|
| 2015 |
Yang L, Achreja A, Moss T, Baddour J, Stilles K, Chiba L, Kim SH, Morse J, Marini J, Sood AK, Ram PT, Nagrath D. Abstract 1208: Glutamine modulates cellular NAD+/NADH homeostasis thereby regulating cancer metastasis, drug sensitivity in cancer cells Cancer Research. 75: 1208-1208. DOI: 10.1158/1538-7445.Am2015-1208 |
0.74 |
|
| 2015 |
Achreja A, Yang L, Moss T, Sehgal V, Marini J, Ram PT, Nagrath D. Abstract 1204: Design of phenotype-driven flux analysis approach for personalized metabolic models of cancer patients Cancer Research. 75: 1204-1204. DOI: 10.1158/1538-7445.Am2015-1204 |
0.75 |
|
| 2014 |
Caneba CA, Yang L, Baddour J, Curtis R, Win J, Hartig S, Marini J, Nagrath D. Nitric oxide is a positive regulator of the Warburg effect in ovarian cancer cells. Cell Death & Disease. 5: e1302. PMID 24967964 DOI: 10.1038/Cddis.2014.264 |
0.772 |
|
| 2014 |
Yang L, Moss T, Mangala LS, Marini J, Zhao H, Wahlig S, Armaiz-Pena G, Jiang D, Achreja A, Win J, Roopaimoole R, Rodriguez-Aguayo C, Mercado-Uribe I, Lopez-Berestein G, Liu J, et al. Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer. Molecular Systems Biology. 10: 728. PMID 24799285 DOI: 10.1002/Msb.20134892 |
0.791 |
|
| 2014 |
Zhao H, Yang L, Achreja A, Marini J, Peehl D, Nagrath D. Abstract 3594: Tumor microenvironment derived exosomes regulate prostate cancer metabolism Cancer Research. 74: 3594-3594. DOI: 10.1158/1538-7445.Am2014-3594 |
0.787 |
|
| 2014 |
Baddour J, Yang L, Marini JC, Franco-Barraza J, Cukierman E, Hu C, Maitra A, Nagrath D. Abstract 3379: Metabolic influences of pancreatic tumor microenvironment on pancreatic cancer cell's metabolism Cancer Research. 74: 3379-3379. DOI: 10.1158/1538-7445.Am2014-3379 |
0.745 |
|
| 2014 |
Yang L, Moss TJ, Marini JC, Mangala S, Wahlig S, Win J, Su D, Sood AK, Ram PT, Nagrath D. Abstract 3377: Glutamine mediated aggressiveness and drug sensitivity in ovarian cancer cells Cancer Research. 74: 3377-3377. DOI: 10.1158/1538-7445.Am2014-3377 |
0.709 |
|
| 2014 |
Achreja A, Yang L, Zhao H, Marini J, Nagrath D. Abstract 3372: Constraints-based metabolic flux analysis approach links tumor stage to metabolic adaptations and survival in cancer cells Cancer Research. 74: 3372-3372. DOI: 10.1158/1538-7445.Am2014-3372 |
0.805 |
|
| 2014 |
Köhring M, Huang S, Jahjah M, Jiang W, Ren W, Willer U, Caneba C, Yang L, Nagrath D, Schade W, Tittel FK. QCL-based TDLAS sensor for detection of NO toward emission measurements from ovarian cancer cells Applied Physics B: Lasers and Optics. 117: 445-451. DOI: 10.1007/S00340-014-5853-7 |
0.588 |
|
| 2013 |
Yang L, Zhao H, Marini JC, Jeter C, Tang D, Nagrath D. Abstract 5413: Role of NANOG in modulating cancer cell metabolism. Cancer Research. 73: 5413-5413. DOI: 10.1158/1538-7445.Am2013-5413 |
0.805 |
|
| 2013 |
Achreja A, Yang L, Zhao H, Marini JC, Nagrath D. Abstract 1892: Integrated energetics and flux analysis reveals differential metabolic reprogramming in highly and less invasive cancer cells. Cancer Research. 73: 1892-1892. DOI: 10.1158/1538-7445.Am2013-1892 |
0.784 |
|
| 2012 |
Caneba CA, Bellance N, Yang L, Pabst L, Nagrath D. Pyruvate uptake is increased in highly invasive ovarian cancer cells under anoikis conditions for anaplerosis, mitochondrial function, and migration. American Journal of Physiology. Endocrinology and Metabolism. 303: E1036-52. PMID 22895781 DOI: 10.1152/Ajpendo.00151.2012 |
0.757 |
|
| 2012 |
Komurov K, Tseng JT, Muller M, Seviour EG, Moss TJ, Yang L, Nagrath D, Ram PT. The glucose-deprivation network counteracts lapatinib-induced toxicity in resistant ErbB2-positive breast cancer cells. Molecular Systems Biology. 8: 596. PMID 22864381 DOI: 10.1038/Msb.2012.25 |
0.645 |
|
| 2012 |
Yang L, Nagrath D. Abstract 5161: Role of glutamine in cancer growth, invasion and progression: Therapeutic modulation of glutamine pathway Cancer Research. 72: 5161-5161. DOI: 10.1158/1538-7445.Am2012-5161 |
0.776 |
|
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