Sheila Francis - Publications

Affiliations: 
Cardiovascular Science Sheffield University, Sheffield, England, United Kingdom 

62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Kidder E, Gangopadhyay S, Francis S, Alfaidi M. "How to Release or Not Release, That Is the Question." A Review of Interleukin-1 Cellular Release Mechanisms in Vascular Inflammation. Journal of the American Heart Association. 13: e032987. PMID 38390810 DOI: 10.1161/JAHA.123.032987  0.663
2021 Iqbal J, Chamberlain J, Alfaidi M, Hughes M, Alizadeh T, Casbolt H, Evans P, Mann B, Motterlini R, Francis S, Gunn J. Carbon monoxide releasing molecule A1 reduces myocardial damage after acute myocardial infarction in a porcine model. Journal of Cardiovascular Pharmacology. PMID 34328710 DOI: 10.1097/FJC.0000000000001067  0.659
2020 Pinteaux E, Abdulaal WH, Mufazalov IA, Humphreys NE, Simonsen-Jackson M, Francis S, Müller W, Waisman A. Cell-specific conditional deletion of interleukin-1 (IL-1) ligands and its receptors: a new toolbox to study the role of IL-1 in health and disease. Journal of Molecular Medicine (Berlin, Germany). PMID 32468079 DOI: 10.1007/S00109-020-01928-5  0.374
2020 Gomez I, Ward B, Souilhol C, Recarti C, Ariaans M, Johnston J, Burnett A, Mahmoud M, Luong LA, West L, Long M, Parry S, Woods R, Hulston C, Benedikter B, ... ... Francis S, et al. Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium. Nature Communications. 11: 214. PMID 31924781 DOI: 10.1038/S41467-019-14043-Y  0.329
2019 Bageghni SA, Hemmings KE, Yuldasheva NY, Maqbool A, Gamboa-Esteves FO, Humphreys NE, Simonsen Jackson M, Denton CP, Francis S, Porter KE, Ainscough JFX, Pinteaux E, Drinkhill MJ, Turner NA. Fibroblast-specific deletion of interleukin-1 receptor-1 reduces adverse cardiac remodeling following myocardial infarction. Jci Insight. 5. PMID 31393855 DOI: 10.1172/Jci.Insight.125074  0.384
2019 Helyes Z, Tékus V, Szentes N, Pohóczky K, Botz B, Kiss T, Kemény Á, Környei Z, Tóth K, Lénárt N, Ábrahám H, Pinteaux E, Francis S, Sensi S, Dénes Á, et al. Transfer of complex regional pain syndrome to mice via human autoantibodies is mediated by interleukin-1-induced mechanisms. Proceedings of the National Academy of Sciences of the United States of America. PMID 31182576 DOI: 10.1073/Pnas.1820168116  0.386
2019 Borland S, Behnsen J, Akerele A, Sherratt MJ, Brennan K, Holt C, Francis S, Canfield A. BS61 PKCαα knock-down enhances intimal calcification in a murine model of atherosclerosis Heart. 105. DOI: 10.1136/Heartjnl-2019-Bcs.221  0.4
2019 Borland S, Facchi C, Behnsen J, Adamson A, Humphrey N, Sherratt MJ, Brennan K, Francis S, Ashton N, Canfield A. BS50 PKCα knock-down increases medial calcification in a murine model of chronic kidney disease Heart. 105. DOI: 10.1136/Heartjnl-2019-Bcs.211  0.367
2019 Kocsy K, Francis S, Kiss-Toth E, Lonsdale R, Majid A, Redgrave J. BS22 Double positive (CD86+ MRC1+) inflammatory macrophages in the pathogenesis of carotid atherosclerosis Heart. 105. DOI: 10.1136/Heartjnl-2019-Bcs.185  0.306
2018 Wong R, Lénárt N, Hill L, Toms L, Coutts G, Martinecz B, Császár E, Nyiri G, Papaemmanouil A, Waisman A, Müller W, Schwaninger M, Rothwell N, Francis S, Pinteaux E, et al. Interleukin-1 mediates ischaemic brain injury via distinct actions on endothelial cells and cholinergic neurons. Brain, Behavior, and Immunity. PMID 30453020 DOI: 10.1016/J.Bbi.2018.11.012  0.361
2018 Alfaidi MA, Chamberlain J, Rothman A, Crossman D, Villa-Uriol MC, Hadoke P, Wu J, Schenkel T, Evans PC, Francis SE. Dietary Docosahexaenoic Acid Reduces Oscillatory Wall Shear Stress, Atherosclerosis, and Hypertension, Most Likely Mediated via an IL-1-Mediated Mechanism. Journal of the American Heart Association. 7. PMID 29960988 DOI: 10.1161/JAHA.118.008757  0.716
2018 Almansouri M, Francis S, Chamberlain J. 140 Acetylated ldl induces IL-1β release from human coronary endothelial cells Heart. 104. DOI: 10.1136/Heartjnl-2018-Bcs.137  0.418
2018 Johnston J, Angyal A, Bauer R, Rader D, Shoulders C, Francis S, Kiss-Toth E. 123 Myeloid TRIB1 controls experimental atherosclerosis Heart. 104. DOI: 10.1136/Heartjnl-2018-Bcs.122  0.364
2018 Kocsy K, Wadanamby S, Tang K, Majid A, Redgrave J, Johnston J, Francis S, Kiss-Toth E. 116 Semi-quantitative imaging of macrophages in human carotid atherosclerotic plaques Heart. 104. DOI: 10.1136/Heartjnl-2018-Bcs.115  0.313
2017 Renshall LJ, Arnold ND, West L, Braithwaite A, Pickworth JA, Walker R, Alfaidi MA, Casbolt H, Thompson AAR, Holt C, Iglarz M, Francis S, Lawrie A. EXPRESS: Selective Improvement of Pulmonary Arterial Hypertension with a Dual ETA/ETB Receptors Antagonist in the Apolipoprotein E-/- Model of PAH and Atherosclerosis. Pulmonary Circulation. 2045893217752328. PMID 29261014 DOI: 10.1177/2045893217752328  0.688
2017 Smith SA, Samokhin AO, Alfadi M, Murphy EC, Rhodes D, Holcombe WML, Kiss-Toth E, Storey RF, Yee SP, Francis SE, Qwarnstrom EE. The IL-1RI Co-Receptor TILRR (FREM1 Isoform 2) Controls Aberrant Inflammatory Responses and Development of Vascular Disease. Jacc. Basic to Translational Science. 2: 398-414. PMID 28920098 DOI: 10.1016/J.Jacbts.2017.03.014  0.305
2016 Bowden N, Feng S, Francis S, Evans P. 211 Non-Canonical NF-Κb Signalling Promotes Endothelial Proliferation in Response to Low Wall Shear Stress Heart. 102: A140.1-A140. DOI: 10.1136/Heartjnl-2016-309890.211  0.328
2016 Wong L, Sharp P, Howarth C, Hoggard N, Berwick J, Francis S. 179 Neurovascular Function in Atherosclerosis Heart. 102: A123.2-A124. DOI: 10.1136/Heartjnl-2016-309890.179  0.339
2015 Alfaidi M, Wilson H, Daigneault M, Burnett A, Ridger V, Chamberlain J, Francis S. Neutrophil Elastase promotes Interleukin-1β secretion from Human Coronary Endothelium. The Journal of Biological Chemistry. PMID 26269588 DOI: 10.1074/Jbc.M115.659029  0.707
2015 Pickworth J, Shay S, Gladson S, Iremonger J, Rothman A, Francis S, West J, Lawrie A. S3 Reduced BMPR2 expression potentiates a pulmonary artery smooth muscle cell specific IL-1ß response Thorax. 70. DOI: 10.1136/Thoraxjnl-2015-207770.9  0.41
2015 Smith S, Samokhin A, Murphy E, Francis S, Qwarnstrom E. 217 Altered Regulation of the Inhibitor IκBα Contributes to Changes in NF-κB Regulated Genes in the TILRR ko Mouse Heart. 101. DOI: 10.1136/Heartjnl-2015-308066.217  0.361
2015 Bazaz R, Francis S, Dockrell D. 215 Increased Atherosclerotic Plaque Macrophage Content following Streptococcus Pneumoniae Pneumonia Heart. 101. DOI: 10.1136/Heartjnl-2015-308066.215  0.352
2015 Alfaidi M, Schenkel T, Evans P, Chamberlain J, Francis S. 192 Dietary Docosahexaenoic Acid Reduced Experimental Atherosclerosis by Inducing Protective Haemodynamic Conditions Heart. 101. DOI: 10.1136/Heartjnl-2015-308066.192  0.706
2015 Johnston J, Angyal A, Alfaidi M, Francis S, Kiss-Toth E. 186 Assessment of Plaque Macrophage Phenotype in situ by Multicolour Fluorescence Microscopy Heart. 101. DOI: 10.1136/Heartjnl-2015-308066.186  0.692
2014 Raina T, Iqbal J, Arnold N, Moore H, Aflatoonian B, Walsh J, Whitehouse S, Al-Lamee K, Francis S, Gunn J. Coronary stents seeded with human trophoblastic endovascular progenitor cells show accelerated strut coverage without excessive neointimal proliferation in a porcine model. Eurointervention : Journal of Europcr in Collaboration With the Working Group On Interventional Cardiology of the European Society of Cardiology. 10: 709-16. PMID 25330503 DOI: 10.4244/Eijv10I6A123  0.302
2014 Steiner T, Francescut L, Byrne S, Hughes T, Jayanthi A, Guschina I, Harwood J, Cianflone K, Stover C, Francis S. Protective role for properdin in progression of experimental murine atherosclerosis. Plos One. 9: e92404. PMID 24667818 DOI: 10.1371/Journal.Pone.0092404  0.366
2014 Dénes Á, Pradillo JM, Drake C, Sharp A, Warn P, Murray KN, Rohit B, Dockrell DH, Chamberlain J, Casbolt H, Francis S, Martinecz B, Nieswandt B, Rothwell NJ, Allan SM. Streptococcus pneumoniae worsens cerebral ischemia via interleukin 1 and platelet glycoprotein Ibα. Annals of Neurology. 75: 670-83. PMID 24644058 DOI: 10.1002/Ana.24146  0.348
2014 Dawson S, Pickworth J, Rothman A, Iremonger J, Arnold N, Francis S, Lawrie A. T5 Opg Regulates Pulmonary Arterial Smooth Muscle Cell Proliferation And The Expression Of Pah-associated Genes Via Fas Thorax. 69. DOI: 10.1136/Thoraxjnl-2014-206260.5  0.34
2014 Alfaidi M, Chamberlain J, Francis S. 212 Docosahexaenoic Acid but not Alpha-linolenic Acid Ameliorates High Fat Diet Induced Atherosclerosis and Hypertension in APOE-/- MICE Via IL-1 Mechanism Heart. 100. DOI: 10.1136/Heartjnl-2014-306118.212  0.725
2014 Murphy E, Samokhin A, Francis S, Bowskill S, Qwarnstrom E. 187 The Inflammatory Phenotype of the Tilrr Knockout Mouse - Mechanisms Undelying Reduced Responses to Vascular Injury Heart. 100. DOI: 10.1136/Heartjnl-2014-306118.187  0.432
2014 Samokhin A, Francis S, Qwarnstrom E. 154 Blocking the IL-1RI Co-receptor TILRR Reduces Vascular Inflammation – in vivo Analysis Using TILRR Knockout Mice Heart. 100. DOI: 10.1136/Heartjnl-2014-306118.154  0.457
2013 West L, Francis S, Storey R. Yia6: Vessel Wall, But Not Platelet, P2Y12 Contributes To Early Atherogenesis Heart. 99. DOI: 10.1136/Heartjnl-2013-304019.273  0.372
2013 Samokhin A, Murphy E, Grant J, Boyle J, Haskard D, Francis S, Qwarnstrom E. 210 A Role For The Il-1Ri Co-Receptor Tilrr In Atherosclerosis And Vascular Repair Heart. 99. DOI: 10.1136/Heartjnl-2013-304019.210  0.45
2012 Sung HY, Francis SE, Arnold ND, Holland K, Ernst V, Angyal A, Kiss-Toth E. Enhanced macrophage tribbles-1 expression in murine experimental atherosclerosis. Biology. 1: 43-57. PMID 24832046 DOI: 10.3390/biology1010043  0.315
2012 Denes A, Drake C, Stordy J, Chamberlain J, McColl BW, Gram H, Crossman D, Francis S, Allan SM, Rothwell NJ. Interleukin-1 mediates neuroinflammatory changes associated with diet-induced atherosclerosis. Journal of the American Heart Association. 1: e002006. PMID 23130147 DOI: 10.1161/Jaha.112.002006  0.427
2012 Francescut L, Steiner T, Byrne S, Cianflone K, Francis S, Stover C. The role of complement in the development and manifestation of murine atherogenic inflammation: novel avenues. Journal of Innate Immunity. 4: 260-72. PMID 22116497 DOI: 10.1159/000332435  0.378
2012 Neilan M, Zhang X, Steiner T, Boyle J, Francis S, Haskard D, Qwarnstrom E. 18 TILRR Functional Mutants Selectively Inhibit Inflammatory and Anti-Apoptotic Responses Heart. 98. DOI: 10.1136/Heartjnl-2012-302951.018  0.391
2012 Hameed A, Arnold N, Chamberlain J, Pickworth J, Newman C, Crossman D, Francis S, Lawrie A. 03 Tissue Trail Drives Pulmonary Vascular Remodeling and its Inhibition Reverses Experimental Pulmonary Arterial Hypertension Heart. 98. DOI: 10.1136/Heartjnl-2012-302951.003  0.373
2011 Lawrie A, Hameed AG, Chamberlain J, Arnold N, Kennerley A, Hopkinson K, Pickworth J, Kiely DG, Crossman DC, Francis SE. Paigen diet-fed apolipoprotein E knockout mice develop severe pulmonary hypertension in an interleukin-1-dependent manner. The American Journal of Pathology. 179: 1693-705. PMID 21835155 DOI: 10.1016/j.ajpath.2011.06.037  0.311
2011 Ellam T, Wilkie M, Chamberlain J, Crossman D, Eastell R, Francis S, Chico TJA. Dietary Phosphate Modulates Atherogenesis and Insulin Resistance in Apolipoprotein E Knockout Mice—Brief Report Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 1988-1990. PMID 21636807 DOI: 10.1161/Atvbaha.111.231001  0.327
2011 Watt V, Chamberlain J, Steiner T, Francis S, Crossman D. TRAIL attenuates the development of atherosclerosis in apolipoprotein E deficient mice. Atherosclerosis. 215: 348-54. PMID 21324463 DOI: 10.1016/J.Atherosclerosis.2011.01.010  0.32
2011 Condliffe R, Pickworth J, Hopkinson K, Hameed A, Walker S, Elliot C, Francis S, Newman C, Crossman D, Morton A, Kiely D, Lawrie A. S69 Serum osteoprotegerin predicts mortality in a prospective study on incident cases of pulmonary arterial hypertension Thorax. 66. DOI: 10.1136/Thoraxjnl-2011-201054B.69  0.305
2011 Steiner T, Francescut L, Stover C, Francis S. 26 The role of properdin in murine atherosclerosis Heart. 97. DOI: 10.1136/Heartjnl-2011-300920B.26  0.303
2011 Neilan M, Boyle J, Lawrie A, Francis S, Haskard D, Qwarnstrom E. 14 The role of TILRR in vascular cell inflammation and development of atherosclerosis Heart. 97. DOI: 10.1136/Heartjnl-2011-300920B.14  0.428
2011 Ellam T, Wilkie M, Crossman D, Francis S, Chico T. YIA 2 The effects of dietary phosphate intake on atherogenesis and insulin resistance in Apolipoprotein E knockout mice Heart. 97. DOI: 10.1136/Heartjnl-2011-300920A.2  0.326
2010 Chamberlain J, Wheatcroft M, Arnold N, Lupton H, Crossman DC, Gunn J, Francis S. A novel mouse model of in situ stenting Cardiovascular Research. 85: 38-44. PMID 19633315 DOI: 10.1093/Cvr/Cvp262  0.328
2010 Neilan M, Zhang X, Francis S, Qwarnstrom EE. BAS/BSCR51 Control of vascular cell inflammatory responses through TILRR, an interleukin 1 co-receptor Heart. 96. DOI: 10.1136/Hrt.2010.205781.62  0.404
2009 Chamberlain J, Francis S, Brookes Z, Shaw G, Graham D, Alp NJ, Dower S, Crossman DC. Interleukin-1 regulates multiple atherogenic mechanisms in response to fat feeding Plos One. 4. PMID 19347044 DOI: 10.1371/Journal.Pone.0005073  0.46
2009 Francis S, Chamberlain J, Brookes Z, Shaw G, Alp N, Rogus J, Kornman K, Crossman D. Abstract: 1509 IL-1 MODULATES BLOOD PRESSURE IN MICE AND MAN Atherosclerosis Supplements. 10. DOI: 10.1016/S1567-5688(09)70454-4  0.377
2008 Lawrie A, Waterman E, Southwood M, Evans D, Suntharalingam J, Francis S, Crossman D, Croucher P, Morrell N, Newman C. Evidence of a role for osteoprotegerin in the pathogenesis of pulmonary arterial hypertension. The American Journal of Pathology. 172: 256-64. PMID 18156213 DOI: 10.2353/Ajpath.2008.070395  0.349
2006 Chamberlain J, Evans D, King A, Dewberry R, Dower S, Crossman D, Francis S. Interleukin-1beta and signaling of interleukin-1 in vascular wall and circulating cells modulates the extent of neointima formation in mice. The American Journal of Pathology. 168: 1396-403. PMID 16565512 DOI: 10.2353/Ajpath.2006.051054  0.396
2006 Dewberry R, Jetha K, Shaw G, Crossman D, Francis S. Interleukin-1 receptor antagonist modulates circulating endothelial progenitor cells in mice Vascular Pharmacology. 45. DOI: 10.1016/J.Vph.2006.08.117  0.332
2005 Ray KK, Francis S, Crossman DC. A potential pharmacogenomic strategy for anticoagulant treatment in non-ST elevation acute coronary syndromes: The role of interleukin-1 receptor antagonist genotype Journal of Thrombosis and Haemostasis. 3: 287-291. PMID 15670034 DOI: 10.1111/J.1538-7836.2005.01125.X  0.358
2004 Francis S. Endothelial progenitor cells and coronary artery disease Heart. 90: 591-592. PMID 15145845 DOI: 10.1136/Hrt.2003.029942  0.323
2004 Morton A, Francis S, Dower S, Arnold N, Gunn J, Grossman D. Interleukin-1 Receptor Antagonist (IL-1ra) Modulates the Porcine Coronary Arterial Response to Oversized Balloon Angioplasty and Stenting Clinical Science. 106. DOI: 10.1042/Cs106002Pa  0.363
2004 Chamberlain J, Dower S, Crossman D, Francis S. Inhibition Of Interleukin-1 Signalling Reduces The Neointimal Response To Arterial Injury And Promotes Vessel Remodelling Cardiovascular Pathology. 13: 116-117. DOI: 10.1016/J.Carpath.2004.03.352  0.317
2004 Morton AC, Varcoe R, Francis S, Dower S, Arnold N, Gunn J, Crossman D. Interleukin-1 Receptor Antagonist (Il-1Ra) Modulates The Response To Oversized Balloon Angioplasty And Stenting In A Porcine Coronary Artery Model Cardiovascular Pathology. 13: 93. DOI: 10.1016/J.Carpath.2004.03.276  0.365
2002 Francis SE, Goh KL, Hodivala-Dilke K, Bader BL, Stark M, Davidson D, Hynes RO. Central roles of alpha5beta1 integrin and fibronectin in vascular development in mouse embryos and embryoid bodies. Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 927-33. PMID 12067900 DOI: 10.1161/01.Atv.0000016045.93313.F2  0.406
2000 Dewberry R, Holden H, Crossman D, Francis S. Interleukin-1 receptor antagonist expression in human endothelial cells and atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 2394-400. PMID 11073843 DOI: 10.1161/01.Atv.20.11.2394  0.379
1999 Chamberlain J, Gunn J, Francis S, Holt C, Crossman D. Temporal and spatial distribution of interleukin-1β in balloon injured porcine coronary arteries Cardiovascular Research. 44: 156-165. PMID 10615399 DOI: 10.1016/S0008-6363(99)00175-3  0.375
1995 Cooper G, Gillot T, Francis S, Angelini GD. Distension produces medial but not endothelial damage in porcine internal mammary artery Cardiovascular Surgery. 3: 171-174. PMID 7606401 DOI: 10.1016/0967-2109(95)90889-D  0.308
1993 Violaris A, Francis S, Holt C, Clelland C, Gadsdon P, Angelini GD. Organ culture of human coronary artery following balloon angioplasty International Journal of Angiology. 2: 105-111. DOI: 10.1007/Bf02651568  0.306
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