Year |
Citation |
Score |
2024 |
Kidder E, Gangopadhyay S, Francis S, Alfaidi M. "How to Release or Not Release, That Is the Question." A Review of Interleukin-1 Cellular Release Mechanisms in Vascular Inflammation. Journal of the American Heart Association. 13: e032987. PMID 38390810 DOI: 10.1161/JAHA.123.032987 |
0.663 |
|
2021 |
Iqbal J, Chamberlain J, Alfaidi M, Hughes M, Alizadeh T, Casbolt H, Evans P, Mann B, Motterlini R, Francis S, Gunn J. Carbon monoxide releasing molecule A1 reduces myocardial damage after acute myocardial infarction in a porcine model. Journal of Cardiovascular Pharmacology. PMID 34328710 DOI: 10.1097/FJC.0000000000001067 |
0.659 |
|
2020 |
Pinteaux E, Abdulaal WH, Mufazalov IA, Humphreys NE, Simonsen-Jackson M, Francis S, Müller W, Waisman A. Cell-specific conditional deletion of interleukin-1 (IL-1) ligands and its receptors: a new toolbox to study the role of IL-1 in health and disease. Journal of Molecular Medicine (Berlin, Germany). PMID 32468079 DOI: 10.1007/S00109-020-01928-5 |
0.374 |
|
2020 |
Gomez I, Ward B, Souilhol C, Recarti C, Ariaans M, Johnston J, Burnett A, Mahmoud M, Luong LA, West L, Long M, Parry S, Woods R, Hulston C, Benedikter B, ... ... Francis S, et al. Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium. Nature Communications. 11: 214. PMID 31924781 DOI: 10.1038/S41467-019-14043-Y |
0.329 |
|
2019 |
Bageghni SA, Hemmings KE, Yuldasheva NY, Maqbool A, Gamboa-Esteves FO, Humphreys NE, Simonsen Jackson M, Denton CP, Francis S, Porter KE, Ainscough JFX, Pinteaux E, Drinkhill MJ, Turner NA. Fibroblast-specific deletion of interleukin-1 receptor-1 reduces adverse cardiac remodeling following myocardial infarction. Jci Insight. 5. PMID 31393855 DOI: 10.1172/Jci.Insight.125074 |
0.384 |
|
2019 |
Helyes Z, Tékus V, Szentes N, Pohóczky K, Botz B, Kiss T, Kemény Á, Környei Z, Tóth K, Lénárt N, Ábrahám H, Pinteaux E, Francis S, Sensi S, Dénes Á, et al. Transfer of complex regional pain syndrome to mice via human autoantibodies is mediated by interleukin-1-induced mechanisms. Proceedings of the National Academy of Sciences of the United States of America. PMID 31182576 DOI: 10.1073/Pnas.1820168116 |
0.386 |
|
2019 |
Borland S, Behnsen J, Akerele A, Sherratt MJ, Brennan K, Holt C, Francis S, Canfield A. BS61 PKCαα knock-down enhances intimal calcification in a murine model of atherosclerosis Heart. 105. DOI: 10.1136/Heartjnl-2019-Bcs.221 |
0.4 |
|
2019 |
Borland S, Facchi C, Behnsen J, Adamson A, Humphrey N, Sherratt MJ, Brennan K, Francis S, Ashton N, Canfield A. BS50 PKCα knock-down increases medial calcification in a murine model of chronic kidney disease Heart. 105. DOI: 10.1136/Heartjnl-2019-Bcs.211 |
0.367 |
|
2019 |
Kocsy K, Francis S, Kiss-Toth E, Lonsdale R, Majid A, Redgrave J. BS22 Double positive (CD86+ MRC1+) inflammatory macrophages in the pathogenesis of carotid atherosclerosis Heart. 105. DOI: 10.1136/Heartjnl-2019-Bcs.185 |
0.306 |
|
2018 |
Wong R, Lénárt N, Hill L, Toms L, Coutts G, Martinecz B, Császár E, Nyiri G, Papaemmanouil A, Waisman A, Müller W, Schwaninger M, Rothwell N, Francis S, Pinteaux E, et al. Interleukin-1 mediates ischaemic brain injury via distinct actions on endothelial cells and cholinergic neurons. Brain, Behavior, and Immunity. PMID 30453020 DOI: 10.1016/J.Bbi.2018.11.012 |
0.361 |
|
2018 |
Alfaidi MA, Chamberlain J, Rothman A, Crossman D, Villa-Uriol MC, Hadoke P, Wu J, Schenkel T, Evans PC, Francis SE. Dietary Docosahexaenoic Acid Reduces Oscillatory Wall Shear Stress, Atherosclerosis, and Hypertension, Most Likely Mediated via an IL-1-Mediated Mechanism. Journal of the American Heart Association. 7. PMID 29960988 DOI: 10.1161/JAHA.118.008757 |
0.716 |
|
2018 |
Almansouri M, Francis S, Chamberlain J. 140 Acetylated ldl induces IL-1β release from human coronary endothelial cells Heart. 104. DOI: 10.1136/Heartjnl-2018-Bcs.137 |
0.418 |
|
2018 |
Johnston J, Angyal A, Bauer R, Rader D, Shoulders C, Francis S, Kiss-Toth E. 123 Myeloid TRIB1 controls experimental atherosclerosis Heart. 104. DOI: 10.1136/Heartjnl-2018-Bcs.122 |
0.364 |
|
2018 |
Kocsy K, Wadanamby S, Tang K, Majid A, Redgrave J, Johnston J, Francis S, Kiss-Toth E. 116 Semi-quantitative imaging of macrophages in human carotid atherosclerotic plaques Heart. 104. DOI: 10.1136/Heartjnl-2018-Bcs.115 |
0.313 |
|
2017 |
Renshall LJ, Arnold ND, West L, Braithwaite A, Pickworth JA, Walker R, Alfaidi MA, Casbolt H, Thompson AAR, Holt C, Iglarz M, Francis S, Lawrie A. EXPRESS: Selective Improvement of Pulmonary Arterial Hypertension with a Dual ETA/ETB Receptors Antagonist in the Apolipoprotein E-/- Model of PAH and Atherosclerosis. Pulmonary Circulation. 2045893217752328. PMID 29261014 DOI: 10.1177/2045893217752328 |
0.688 |
|
2017 |
Smith SA, Samokhin AO, Alfadi M, Murphy EC, Rhodes D, Holcombe WML, Kiss-Toth E, Storey RF, Yee SP, Francis SE, Qwarnstrom EE. The IL-1RI Co-Receptor TILRR (FREM1 Isoform 2) Controls Aberrant Inflammatory Responses and Development of Vascular Disease. Jacc. Basic to Translational Science. 2: 398-414. PMID 28920098 DOI: 10.1016/J.Jacbts.2017.03.014 |
0.305 |
|
2016 |
Bowden N, Feng S, Francis S, Evans P. 211 Non-Canonical NF-Κb Signalling Promotes Endothelial Proliferation in Response to Low Wall Shear Stress Heart. 102: A140.1-A140. DOI: 10.1136/Heartjnl-2016-309890.211 |
0.328 |
|
2016 |
Wong L, Sharp P, Howarth C, Hoggard N, Berwick J, Francis S. 179 Neurovascular Function in Atherosclerosis Heart. 102: A123.2-A124. DOI: 10.1136/Heartjnl-2016-309890.179 |
0.339 |
|
2015 |
Alfaidi M, Wilson H, Daigneault M, Burnett A, Ridger V, Chamberlain J, Francis S. Neutrophil Elastase promotes Interleukin-1β secretion from Human Coronary Endothelium. The Journal of Biological Chemistry. PMID 26269588 DOI: 10.1074/Jbc.M115.659029 |
0.707 |
|
2015 |
Pickworth J, Shay S, Gladson S, Iremonger J, Rothman A, Francis S, West J, Lawrie A. S3 Reduced BMPR2 expression potentiates a pulmonary artery smooth muscle cell specific IL-1ß response Thorax. 70. DOI: 10.1136/Thoraxjnl-2015-207770.9 |
0.41 |
|
2015 |
Smith S, Samokhin A, Murphy E, Francis S, Qwarnstrom E. 217 Altered Regulation of the Inhibitor IκBα Contributes to Changes in NF-κB Regulated Genes in the TILRR ko Mouse Heart. 101. DOI: 10.1136/Heartjnl-2015-308066.217 |
0.361 |
|
2015 |
Bazaz R, Francis S, Dockrell D. 215 Increased Atherosclerotic Plaque Macrophage Content following Streptococcus Pneumoniae Pneumonia Heart. 101. DOI: 10.1136/Heartjnl-2015-308066.215 |
0.352 |
|
2015 |
Alfaidi M, Schenkel T, Evans P, Chamberlain J, Francis S. 192 Dietary Docosahexaenoic Acid Reduced Experimental Atherosclerosis by Inducing Protective Haemodynamic Conditions Heart. 101. DOI: 10.1136/Heartjnl-2015-308066.192 |
0.706 |
|
2015 |
Johnston J, Angyal A, Alfaidi M, Francis S, Kiss-Toth E. 186 Assessment of Plaque Macrophage Phenotype in situ by Multicolour Fluorescence Microscopy Heart. 101. DOI: 10.1136/Heartjnl-2015-308066.186 |
0.692 |
|
2014 |
Raina T, Iqbal J, Arnold N, Moore H, Aflatoonian B, Walsh J, Whitehouse S, Al-Lamee K, Francis S, Gunn J. Coronary stents seeded with human trophoblastic endovascular progenitor cells show accelerated strut coverage without excessive neointimal proliferation in a porcine model. Eurointervention : Journal of Europcr in Collaboration With the Working Group On Interventional Cardiology of the European Society of Cardiology. 10: 709-16. PMID 25330503 DOI: 10.4244/Eijv10I6A123 |
0.302 |
|
2014 |
Steiner T, Francescut L, Byrne S, Hughes T, Jayanthi A, Guschina I, Harwood J, Cianflone K, Stover C, Francis S. Protective role for properdin in progression of experimental murine atherosclerosis. Plos One. 9: e92404. PMID 24667818 DOI: 10.1371/Journal.Pone.0092404 |
0.366 |
|
2014 |
Dénes Ã, Pradillo JM, Drake C, Sharp A, Warn P, Murray KN, Rohit B, Dockrell DH, Chamberlain J, Casbolt H, Francis S, Martinecz B, Nieswandt B, Rothwell NJ, Allan SM. Streptococcus pneumoniae worsens cerebral ischemia via interleukin 1 and platelet glycoprotein Ibα. Annals of Neurology. 75: 670-83. PMID 24644058 DOI: 10.1002/Ana.24146 |
0.348 |
|
2014 |
Dawson S, Pickworth J, Rothman A, Iremonger J, Arnold N, Francis S, Lawrie A. T5 Opg Regulates Pulmonary Arterial Smooth Muscle Cell Proliferation And The Expression Of Pah-associated Genes Via Fas Thorax. 69. DOI: 10.1136/Thoraxjnl-2014-206260.5 |
0.34 |
|
2014 |
Alfaidi M, Chamberlain J, Francis S. 212 Docosahexaenoic Acid but not Alpha-linolenic Acid Ameliorates High Fat Diet Induced Atherosclerosis and Hypertension in APOE-/- MICE Via IL-1 Mechanism Heart. 100. DOI: 10.1136/Heartjnl-2014-306118.212 |
0.725 |
|
2014 |
Murphy E, Samokhin A, Francis S, Bowskill S, Qwarnstrom E. 187 The Inflammatory Phenotype of the Tilrr Knockout Mouse - Mechanisms Undelying Reduced Responses to Vascular Injury Heart. 100. DOI: 10.1136/Heartjnl-2014-306118.187 |
0.432 |
|
2014 |
Samokhin A, Francis S, Qwarnstrom E. 154 Blocking the IL-1RI Co-receptor TILRR Reduces Vascular Inflammation – in vivo Analysis Using TILRR Knockout Mice Heart. 100. DOI: 10.1136/Heartjnl-2014-306118.154 |
0.457 |
|
2013 |
West L, Francis S, Storey R. Yia6: Vessel Wall, But Not Platelet, P2Y12 Contributes To Early Atherogenesis Heart. 99. DOI: 10.1136/Heartjnl-2013-304019.273 |
0.372 |
|
2013 |
Samokhin A, Murphy E, Grant J, Boyle J, Haskard D, Francis S, Qwarnstrom E. 210 A Role For The Il-1Ri Co-Receptor Tilrr In Atherosclerosis And Vascular Repair Heart. 99. DOI: 10.1136/Heartjnl-2013-304019.210 |
0.45 |
|
2012 |
Sung HY, Francis SE, Arnold ND, Holland K, Ernst V, Angyal A, Kiss-Toth E. Enhanced macrophage tribbles-1 expression in murine experimental atherosclerosis. Biology. 1: 43-57. PMID 24832046 DOI: 10.3390/biology1010043 |
0.315 |
|
2012 |
Denes A, Drake C, Stordy J, Chamberlain J, McColl BW, Gram H, Crossman D, Francis S, Allan SM, Rothwell NJ. Interleukin-1 mediates neuroinflammatory changes associated with diet-induced atherosclerosis. Journal of the American Heart Association. 1: e002006. PMID 23130147 DOI: 10.1161/Jaha.112.002006 |
0.427 |
|
2012 |
Francescut L, Steiner T, Byrne S, Cianflone K, Francis S, Stover C. The role of complement in the development and manifestation of murine atherogenic inflammation: novel avenues. Journal of Innate Immunity. 4: 260-72. PMID 22116497 DOI: 10.1159/000332435 |
0.378 |
|
2012 |
Neilan M, Zhang X, Steiner T, Boyle J, Francis S, Haskard D, Qwarnstrom E. 18 TILRR Functional Mutants Selectively Inhibit Inflammatory and Anti-Apoptotic Responses Heart. 98. DOI: 10.1136/Heartjnl-2012-302951.018 |
0.391 |
|
2012 |
Hameed A, Arnold N, Chamberlain J, Pickworth J, Newman C, Crossman D, Francis S, Lawrie A. 03 Tissue Trail Drives Pulmonary Vascular Remodeling and its Inhibition Reverses Experimental Pulmonary Arterial Hypertension Heart. 98. DOI: 10.1136/Heartjnl-2012-302951.003 |
0.373 |
|
2011 |
Lawrie A, Hameed AG, Chamberlain J, Arnold N, Kennerley A, Hopkinson K, Pickworth J, Kiely DG, Crossman DC, Francis SE. Paigen diet-fed apolipoprotein E knockout mice develop severe pulmonary hypertension in an interleukin-1-dependent manner. The American Journal of Pathology. 179: 1693-705. PMID 21835155 DOI: 10.1016/j.ajpath.2011.06.037 |
0.311 |
|
2011 |
Ellam T, Wilkie M, Chamberlain J, Crossman D, Eastell R, Francis S, Chico TJA. Dietary Phosphate Modulates Atherogenesis and Insulin Resistance in Apolipoprotein E Knockout Mice—Brief Report Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 1988-1990. PMID 21636807 DOI: 10.1161/Atvbaha.111.231001 |
0.327 |
|
2011 |
Watt V, Chamberlain J, Steiner T, Francis S, Crossman D. TRAIL attenuates the development of atherosclerosis in apolipoprotein E deficient mice. Atherosclerosis. 215: 348-54. PMID 21324463 DOI: 10.1016/J.Atherosclerosis.2011.01.010 |
0.32 |
|
2011 |
Condliffe R, Pickworth J, Hopkinson K, Hameed A, Walker S, Elliot C, Francis S, Newman C, Crossman D, Morton A, Kiely D, Lawrie A. S69 Serum osteoprotegerin predicts mortality in a prospective study on incident cases of pulmonary arterial hypertension Thorax. 66. DOI: 10.1136/Thoraxjnl-2011-201054B.69 |
0.305 |
|
2011 |
Steiner T, Francescut L, Stover C, Francis S. 26 The role of properdin in murine atherosclerosis Heart. 97. DOI: 10.1136/Heartjnl-2011-300920B.26 |
0.303 |
|
2011 |
Neilan M, Boyle J, Lawrie A, Francis S, Haskard D, Qwarnstrom E. 14 The role of TILRR in vascular cell inflammation and development of atherosclerosis Heart. 97. DOI: 10.1136/Heartjnl-2011-300920B.14 |
0.428 |
|
2011 |
Ellam T, Wilkie M, Crossman D, Francis S, Chico T. YIA 2 The effects of dietary phosphate intake on atherogenesis and insulin resistance in Apolipoprotein E knockout mice Heart. 97. DOI: 10.1136/Heartjnl-2011-300920A.2 |
0.326 |
|
2010 |
Chamberlain J, Wheatcroft M, Arnold N, Lupton H, Crossman DC, Gunn J, Francis S. A novel mouse model of in situ stenting Cardiovascular Research. 85: 38-44. PMID 19633315 DOI: 10.1093/Cvr/Cvp262 |
0.328 |
|
2010 |
Neilan M, Zhang X, Francis S, Qwarnstrom EE. BAS/BSCR51 Control of vascular cell inflammatory responses through TILRR, an interleukin 1 co-receptor Heart. 96. DOI: 10.1136/Hrt.2010.205781.62 |
0.404 |
|
2009 |
Chamberlain J, Francis S, Brookes Z, Shaw G, Graham D, Alp NJ, Dower S, Crossman DC. Interleukin-1 regulates multiple atherogenic mechanisms in response to fat feeding Plos One. 4. PMID 19347044 DOI: 10.1371/Journal.Pone.0005073 |
0.46 |
|
2009 |
Francis S, Chamberlain J, Brookes Z, Shaw G, Alp N, Rogus J, Kornman K, Crossman D. Abstract: 1509 IL-1 MODULATES BLOOD PRESSURE IN MICE AND MAN Atherosclerosis Supplements. 10. DOI: 10.1016/S1567-5688(09)70454-4 |
0.377 |
|
2008 |
Lawrie A, Waterman E, Southwood M, Evans D, Suntharalingam J, Francis S, Crossman D, Croucher P, Morrell N, Newman C. Evidence of a role for osteoprotegerin in the pathogenesis of pulmonary arterial hypertension. The American Journal of Pathology. 172: 256-64. PMID 18156213 DOI: 10.2353/Ajpath.2008.070395 |
0.349 |
|
2006 |
Chamberlain J, Evans D, King A, Dewberry R, Dower S, Crossman D, Francis S. Interleukin-1beta and signaling of interleukin-1 in vascular wall and circulating cells modulates the extent of neointima formation in mice. The American Journal of Pathology. 168: 1396-403. PMID 16565512 DOI: 10.2353/Ajpath.2006.051054 |
0.396 |
|
2006 |
Dewberry R, Jetha K, Shaw G, Crossman D, Francis S. Interleukin-1 receptor antagonist modulates circulating endothelial progenitor cells in mice Vascular Pharmacology. 45. DOI: 10.1016/J.Vph.2006.08.117 |
0.332 |
|
2005 |
Ray KK, Francis S, Crossman DC. A potential pharmacogenomic strategy for anticoagulant treatment in non-ST elevation acute coronary syndromes: The role of interleukin-1 receptor antagonist genotype Journal of Thrombosis and Haemostasis. 3: 287-291. PMID 15670034 DOI: 10.1111/J.1538-7836.2005.01125.X |
0.358 |
|
2004 |
Francis S. Endothelial progenitor cells and coronary artery disease Heart. 90: 591-592. PMID 15145845 DOI: 10.1136/Hrt.2003.029942 |
0.323 |
|
2004 |
Morton A, Francis S, Dower S, Arnold N, Gunn J, Grossman D. Interleukin-1 Receptor Antagonist (IL-1ra) Modulates the Porcine Coronary Arterial Response to Oversized Balloon Angioplasty and Stenting Clinical Science. 106. DOI: 10.1042/Cs106002Pa |
0.363 |
|
2004 |
Chamberlain J, Dower S, Crossman D, Francis S. Inhibition Of Interleukin-1 Signalling Reduces The Neointimal Response To Arterial Injury And Promotes Vessel Remodelling Cardiovascular Pathology. 13: 116-117. DOI: 10.1016/J.Carpath.2004.03.352 |
0.317 |
|
2004 |
Morton AC, Varcoe R, Francis S, Dower S, Arnold N, Gunn J, Crossman D. Interleukin-1 Receptor Antagonist (Il-1Ra) Modulates The Response To Oversized Balloon Angioplasty And Stenting In A Porcine Coronary Artery Model Cardiovascular Pathology. 13: 93. DOI: 10.1016/J.Carpath.2004.03.276 |
0.365 |
|
2002 |
Francis SE, Goh KL, Hodivala-Dilke K, Bader BL, Stark M, Davidson D, Hynes RO. Central roles of alpha5beta1 integrin and fibronectin in vascular development in mouse embryos and embryoid bodies. Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 927-33. PMID 12067900 DOI: 10.1161/01.Atv.0000016045.93313.F2 |
0.406 |
|
2000 |
Dewberry R, Holden H, Crossman D, Francis S. Interleukin-1 receptor antagonist expression in human endothelial cells and atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 2394-400. PMID 11073843 DOI: 10.1161/01.Atv.20.11.2394 |
0.379 |
|
1999 |
Chamberlain J, Gunn J, Francis S, Holt C, Crossman D. Temporal and spatial distribution of interleukin-1β in balloon injured porcine coronary arteries Cardiovascular Research. 44: 156-165. PMID 10615399 DOI: 10.1016/S0008-6363(99)00175-3 |
0.375 |
|
1995 |
Cooper G, Gillot T, Francis S, Angelini GD. Distension produces medial but not endothelial damage in porcine internal mammary artery Cardiovascular Surgery. 3: 171-174. PMID 7606401 DOI: 10.1016/0967-2109(95)90889-D |
0.308 |
|
1993 |
Violaris A, Francis S, Holt C, Clelland C, Gadsdon P, Angelini GD. Organ culture of human coronary artery following balloon angioplasty International Journal of Angiology. 2: 105-111. DOI: 10.1007/Bf02651568 |
0.306 |
|
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