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Clemens Grassberger, PhD - Publications

Affiliations: 
2014 Medical Physics ETH Universität Zürich/Harvard University 
 2014- Radiation Oncology Harvard University, Cambridge, MA, United States 
Area:
Radiation Physics; Biophysics; Immunomodulation
Website:
https://gray.mgh.harvard.edu/people-directory/research/66-clemens-grassberger-phd
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Year Citation  Score
2020 McClatchy DM, Willers H, Hata AN, Piotrowska Z, Sequist LV, Paganetti H, Grassberger C. Modeling Resistance and Recurrence Patterns of Combined Targeted-Chemoradiotherapy Predicts Benefit of Shorter Induction Period. Cancer Research. 80: 5121-5133. PMID 32907839 DOI: 10.1158/0008-5472.Can-19-3883  0.633
2020 Mohan R, Liu AY, Brown PD, Mahajan A, Dinh J, Chung C, McAvoy S, McAleer MF, Lin SH, Li J, Ghia AJ, Zhu C, Sulman EP, de Groot JF, Heimberger AB, ... ... Grassberger C, et al. Proton Therapy Reduces the Likelihood of High-Grade Radiation-Induced Lymphopenia in Glioblastoma Patients: Phase II Randomized Study of Protons vs. Photons. Neuro-Oncology. PMID 32750703 DOI: 10.1093/Neuonc/Noaa182  0.4
2020 Baliga S, Bajaj BVM, Kabarriti R, Grassberger C, Patteson B, Yeap B, Fox JL, Garg MK, Yock TI. Prolongation of radiotherapy duration is associated with inferior overall survival in patients with pediatric medulloblastoma and central nervous system primitive neuroectodermal tumors. Pediatric Blood & Cancer. e28558. PMID 32710698 DOI: 10.1002/Pbc.28558  0.31
2020 Sung W, Grassberger C, McNamara AL, Basler L, Ehrbar S, Tanadini-Lang S, Hong TS, Paganetti H. A Tumor-Immune Interaction Model for Hepatocellular Carcinoma based on measured Lymphocyte Counts in Patients undergoing Radiotherapy. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. PMID 32679308 DOI: 10.1016/J.Radonc.2020.07.025  0.774
2020 Ho AY, Wright JL, Blitzblau RC, Mutter RW, Duda GD, Norton L, Bardia A, Spring L, Isakoff SJ, Chen JH, Grassberger C, Bellon JR, Beriwal S, Khan AJ, Speers C, et al. Optimizing Radiotherapy to Boost Systemic Immune Responses in Breast Cancer: A Critical Review for Breast Radiation Oncologists. International Journal of Radiation Oncology, Biology, Physics. PMID 32417409 DOI: 10.1016/J.Ijrobp.2020.05.011  0.354
2020 Pursley J, El Naqa I, Sanford NN, Noe B, Wo JY, Eyler CE, Hwang M, Brock KK, Yeap BY, Wolfgang JA, Hong TS, Grassberger C. Dosimetric analysis and normal tissue complication probability modeling of Child-Pugh score and Albumin-Bilirubin grade increase after hepatic irradiation. International Journal of Radiation Oncology, Biology, Physics. PMID 32353390 DOI: 10.1016/J.Ijrobp.2020.04.027  0.316
2020 Wang CC, McNamara AL, Shin J, Schuemann J, Grassberger C, Taghian AG, Jimenez RB, MacDonald SM, Paganetti H. End-of-range Radiobiological Effect on Rib Fractures in Patients Receiving Proton Therapy for Breast Cancer. International Journal of Radiation Oncology, Biology, Physics. PMID 32240774 DOI: 10.1016/J.Ijrobp.2020.03.012  0.616
2020 Hammi A, Paganetti H, Grassberger C. 4D blood flow model for dose calculation to circulating blood and lymphocytes. Physics in Medicine and Biology. 65: 055008. PMID 32119649 DOI: 10.1088/1361-6560/Ab6C41  0.663
2019 Grassberger C, Huber K, Jacob NK, Green MD, Mahler P, Prisciandaro J, Dominello M, Joiner MC, Burmeister J. Three discipline collaborative radiation therapy (3DCRT) special debate: The single most important factor in determining the future of SBRT is immune response. Journal of Applied Clinical Medical Physics. PMID 31573143 DOI: 10.1002/Acm2.12728  0.354
2019 Grassberger C, G Ellsworth S, Q Wilks M, K Keane F, S Loeffler J. Assessing the interactions between radiotherapy and antitumour immunity. Nature Reviews. Clinical Oncology. PMID 31243334 DOI: 10.1038/S41571-019-0238-9  0.322
2019 Grassberger C, McClatchy DM, Geng C, Kamran SC, Fintelmann F, Maruvka YE, Piotrowska Z, Willers H, Sequist LV, Hata AN, Paganetti H. Patient-specific tumor growth trajectories determine persistent and resistant cancer cell populations during treatment with targeted therapies. Cancer Research. PMID 31113818 DOI: 10.1158/0008-5472.Can-18-3652  0.594
2019 Li Y, Dykstra M, Best TD, Pursley J, Chopra N, Keane FK, Khandekar MJ, Sharp GC, Paganetti H, Willers H, Fintelmann FJ, Grassberger C. Differential inflammatory response dynamics in normal lung following stereotactic body radiation therapy with protons versus photons. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 136: 169-175. PMID 31015121 DOI: 10.1016/J.Radonc.2019.04.004  0.652
2019 Oesten H, von Neubeck C, Jakob A, Enghardt W, Krause M, McMahon SJ, Grassberger C, Paganetti H, Lühr A. Predicting Cancer Cell Survival Based on Measurable Cell Characteristics. Radiation Research. PMID 31008688 DOI: 10.1667/Rr15265.1  0.614
2019 McClatchy D, Paganetti H, Hata A, Piotrowska Z, Sequist L, Willers H, Grassberger C. Optimizing the Administration of Tyrosine Kinase Inhibitors with Chemoradiotherapy to Improve Outcomes in Locally Advanced, EGFR+ NSCLC Using an Evolutionary Tumor Progression Model International Journal of Radiation Oncology*Biology*Physics. 105: E795-E796. DOI: 10.1016/J.Ijrobp.2019.06.2480  0.566
2019 Wang C, McNamara A, Shin J, Grassberger C, Jimenez R, MacDonald S, Paganetti H. An Increased Rib Fracture Rate in Patients Receiving Proton Therapy for Breast Cancer is Correlated with the End-of-range Radiobiological Effect International Journal of Radiation Oncology*Biology*Physics. 105: E61. DOI: 10.1016/J.Ijrobp.2019.06.2401  0.598
2019 Ioakeim-Ioannidou M, Liu KX, Susko MS, Rao AD, Zaslowe-Dude C, Marcus KJ, Yock TI, Grassberger C, Braunstein SE, Haas-Kogan DA, Terezakis SA, MacDonald S. A Multi-Institutional Retrospective Comparative Analysis of Proton and Photon Therapy-Induced Hematologic Toxicity in Medulloblastoma Patients. International Journal of Radiation Oncology Biology Physics. 105. DOI: 10.1016/J.Ijrobp.2019.06.1164  0.361
2018 Chen Y, Grassberger C, Li J, Hong TS, Paganetti H. Impact of potentially variable RBE in liver proton therapy. Physics in Medicine and Biology. PMID 30183674 DOI: 10.1088/1361-6560/Aadf24  0.644
2018 Sung W, Jeong Y, Kim H, Jeong H, Grassberger C, Jung S, Ahn GO, Kim IH, Schuemann J, Lee K, Ye SJ. Computational Modeling and Clonogenic Assay for Radioenhancement of Gold Nanoparticles Using 3D Live Cell Images. Radiation Research. PMID 30142031 DOI: 10.1667/Rr15134.1  0.762
2018 Geng C, Paganetti H, Grassberger C. Author Correction: Prediction of Treatment Response for Combined Chemo- and Radiation Therapy for Non-Small Cell Lung Cancer Patients Using a Bio-Mathematical Model. Scientific Reports. 8: 12631. PMID 30115991 DOI: 10.1038/S41598-018-30761-7  0.646
2018 Underwood TSA, Grassberger C, Bass R, MacDonald SM, Meyersohn NM, Yeap BY, Jimenez RB, Paganetti H. Asymptomatic Late-phase Radiographic Changes Among Chest-Wall Patients Are Associated With a Proton RBE Exceeding 1.1. International Journal of Radiation Oncology, Biology, Physics. 101: 809-819. PMID 29976493 DOI: 10.1016/J.Ijrobp.2018.03.037  0.619
2018 St James S, Grassberger C, Lu HM. Considerations when treating lung cancer with passive scatter or active scanning proton therapy. Translational Lung Cancer Research. 7: 210-215. PMID 29876321 DOI: 10.21037/Tlcr.2018.04.01  0.523
2018 Grassberger C, Hong TS, Hato T, Yeap BY, Wo JY, Tracy M, Bortfeld T, Wolfgang JA, Eyler CE, Goyal L, Clark JW, Crane CH, Koay EJ, Cobbold M, DeLaney TF, et al. Differential Association Between Circulating Lymphocyte Populations With Outcome After Radiation Therapy in Subtypes of Liver Cancer. International Journal of Radiation Oncology, Biology, Physics. PMID 29859792 DOI: 10.1016/J.Ijrobp.2018.04.026  0.378
2018 Botas P, Grassberger C, Sharp G, Paganetti H. Density overwrites of internal tumor volumes in intensity modulated proton therapy plans for mobile lung tumors. Physics in Medicine and Biology. 63: 035023. PMID 29219119 DOI: 10.1088/1361-6560/Aaa035  0.696
2018 Oesten H, Von Neubeck C, Löck S, Enghardt W, Krause M, McMahon S, Grassberger C, Paganetti H, Lühr A. EP-2332: A concept to personalize radiation oncology: Predicting cell-specific survival prior to treatment Radiotherapy and Oncology. 127: S1286-S1287. DOI: 10.1016/S0167-8140(18)32641-0  0.602
2018 Hoebel KV, Yeap BY, Wo JY, Eyler C, Wolfgang JA, Paganetti H, Hong TS, Grassberger C. Proton Therapy and the Role of Dosimetric Parameters as Predictors for Normal Tissue Complications after Liver-Directed Stereotactic Body Radiation Therapy International Journal of Radiation Oncology Biology Physics. 102. DOI: 10.1016/J.Ijrobp.2018.07.476  0.628
2017 Geng C, Paganetti H, Grassberger C. Prediction of Treatment Response for Combined Chemo- and Radiation Therapy for Non-Small Cell Lung Cancer Patients Using a Bio-Mathematical Model. Scientific Reports. 7: 13542. PMID 29051600 DOI: 10.1038/S41598-017-13646-Z  0.667
2017 Manem VSK, Grassberger C, Paganetti H. Predicting Organ-Specific Risk Interactions between Radiation and Chemotherapy in Secondary Cancer Survivors. Cancers. 9. PMID 28878202 DOI: 10.3390/Cancers9090119  0.622
2017 Grassberger C, Paganetti H. Varying relative biological effectiveness in proton therapy: knowledge gaps versus clinical significance. Acta Oncologica (Stockholm, Sweden). 56: 761-762. PMID 28464735 DOI: 10.1080/0284186X.2017.1316516  0.609
2017 Grassberger C, Scott JG, Paganetti H. Biomathematical Optimization of Radiation Therapy in the Era of Targeted Agents. International Journal of Radiation Oncology, Biology, Physics. 97: 13-17. PMID 27979444 DOI: 10.1016/J.Ijrobp.2016.09.008  0.629
2017 Underwood T, Grassberger C, Bass R, Jimenez R, Meyersohn N, Yeap B, MacDonald S, Paganetti H. OC-0245: Clinical evidence that end-of-range proton RBE exceeds 1.1: lung density changes following chest RT Radiotherapy and Oncology. 123: S123-S124. DOI: 10.1016/S0167-8140(17)30688-6  0.604
2017 Giantsoudi D, Unkelbach J, Botas P, Grassberger C, Paganetti H. Can Robust Optimization for Range Uncertainty in Proton Therapy Act as a Surrogate for Biological Optimization? International Journal of Radiation Oncology*Biology*Physics. 99: S106-S107. DOI: 10.1016/J.Ijrobp.2017.06.253  0.595
2017 Hong TS, Grassberger C, Yeap BY, Wo JY, Goyal L, DeLaney TF, Zhu AX, Duda DG. Oral Scientific SessionsHepatocyte Growth Factor is Associated With Liver Dysfunction and Survival: Biomarker Results of a Phase 2 Study of Proton Beam Therapy in Patients with Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma International Journal of Radiation Oncology Biology Physics. 99. DOI: 10.1016/J.Ijrobp.2017.06.215  0.308
2017 Botas P, Grassberger C, Sharp G, Paganetti H. Comparison of Internal Tumor Volume Definition Strategies to Reduce Plan Degradation of Intensity Modulated Proton Therapy Plans for Mobile Lung Tumor International Journal of Radiation Oncology*Biology*Physics. 99: E641. DOI: 10.1016/J.Ijrobp.2017.06.2149  0.641
2017 Grassberger C, McNamara A, Hess C, MacDonald S, Tarbell N, Ebb D, Paganetti H, Yock T. Hematologic Toxicities During Treatment Allow for Improved Prediction of Recurrences in Pediatric Medulloblastoma International Journal of Radiation Oncology*Biology*Physics. 99: E591-E592. DOI: 10.1016/J.Ijrobp.2017.06.2025  0.576
2017 Geng C, Paganetti H, Grassberger C. Tumor-Specific Modeling of Chemotherapy Combined With Radiation in Stage III NSCLC Suggests Novel Patient Stratification Criteria for Therapy Sequencing International Journal of Radiation Oncology*Biology*Physics. 99: S35-S36. DOI: 10.1016/J.Ijrobp.2017.06.095  0.636
2017 Grassberger C, Kamran S, Bass R, Fintelmann F, Piotrowska Z, Sequist L, Willers H, Paganetti H. Image-Based Modeling of EGFR TKI Resistance Development and Possible Applications to Optimizing Induction Regimen in Stage III Nonsmall Cell Lung Cancer International Journal of Radiation Oncology*Biology*Physics. 99: S34-S35. DOI: 10.1016/J.Ijrobp.2017.06.093  0.592
2016 Varlotto J, DiMaio C, Grassberger C, Tangel M, Mackley H, Pavelic M, Specht C, Sogge S, Nguyen D, Glantz M, Saw C, Upadhyay U, Moser R, Yunus S, Rava P, et al. Multi-modality management of craniopharyngioma: a review of various treatments and their outcomes. Neuro-Oncology Practice. 3: 173-187. PMID 31386091 DOI: 10.1093/Nop/Npv029  0.356
2016 Underwood T, Grassberger C, Willers H, MacDonald S, Jimenez R, Paganetti H. WE-FG-202-03: Quantitative CT-Based Analysis to Assess Lung Injury Following Proton Radiotherapy. Medical Physics. 43: 3827. PMID 28048337 DOI: 10.1118/1.4957915  0.675
2016 Botas P, Grassberger C, Sharp G, Qin N, Jia X, Jiang S, Paganetti H. SU-G-TeP1-06: Fast GPU Framework for Four-Dimensional Monte Carlo in Adaptive Intensity Modulated Proton Therapy (IMPT) for Mobile Tumors. Medical Physics. 43: 3653. PMID 28048238 DOI: 10.1118/1.4956996  0.665
2016 Grassberger C, Paganetti H. Methodologies in the modeling of combined chemo-radiation treatments. Physics in Medicine and Biology. 61: R344-R367. PMID 27758980 DOI: 10.1088/0031-9155/61/21/R344  0.67
2016 Grassberger C, Dinkelborg P, McNamara A, Schuemann JP, McMahon SJ, Willers H, Paganetti H, Wang M. Digital Holographic Microscopy for Nanoscale Dose Calculation and Assessing Gold Nanoparticle Uptake in Live Cells. International Journal of Radiation Oncology, Biology, Physics. 96: S169-S170. PMID 27675694 DOI: 10.1016/J.Ijrobp.2016.06.426  0.585
2016 Underwood TS, Grassberger C, MacDonald S, Jimenez RB, Paganetti H. Late-Phase Radiographic Changes in Lung Following Proton Irradiation of the Chest Wall. International Journal of Radiation Oncology, Biology, Physics. 96: S122. PMID 27675577 DOI: 10.1016/J.Ijrobp.2016.06.297  0.605
2016 Zureick AH, Pulsifer M, Niemierko A, Nichols AJ, Paganetti H, Grassberger C, Fullerton BC, Khan F, Tarbell NJ, MacDonald S, Yock TI. Elevated Proton Radiation Therapy Dose to Left Temporal Lobe or Whole-Brain Correlates With Decline in Full-Scale IQ Components for Pediatric CNS Tumor Survivors. International Journal of Radiation Oncology, Biology, Physics. 96: S120. PMID 27675573 DOI: 10.1016/J.Ijrobp.2016.06.293  0.641
2016 Verburg JM, Grassberger C, Dowdell S, Schuemann J, Seco J, Paganetti H. Automated Monte Carlo Simulation of Proton Therapy Treatment Plans. Technology in Cancer Research & Treatment. 15: NP35-NP46. PMID 26596915 DOI: 10.1177/1533034615614139  0.642
2016 Dowdell S, Grassberger C, Sharp G, Paganetti H. Fractionated Lung IMPT Treatments: Sensitivity to Setup Uncertainties and Motion Effects Based on Single-Field Homogeneity. Technology in Cancer Research & Treatment. 15: 689-96. PMID 26208837 DOI: 10.1177/1533034615595761  0.641
2016 Grassberger C, Paganetti H. WE-H-BRA-03: Development of a Model to Include the Evolution of Resistant Tumor Subpopulations Into the Treatment Optimization Process for Schedules Involving Targeted Agents in Chemoradiation Therapy Medical Physics. 43: 3843-3843. DOI: 10.1118/1.4957994  0.649
2015 Phillips J, Gueorguiev G, Grassberger C, Paganetti H, Sharp G. SU-E-T-639: Proton Dose Calculation for Irregular Motion Using a Sliding Interface. Medical Physics. 42: 3483. PMID 26128302 DOI: 10.1118/1.4925002  0.666
2015 Schuemann J, Giantsoudi D, Grassberger C, Moteabbed M, Min CH, Paganetti H. Assessing the Clinical Impact of Approximations in Analytical Dose Calculations for Proton Therapy. International Journal of Radiation Oncology, Biology, Physics. 92: 1157-64. PMID 26025779 DOI: 10.1016/J.Ijrobp.2015.04.006  0.671
2015 Grassberger C, Dowdell S, Sharp G, Paganetti H. Motion mitigation for lung cancer patients treated with active scanning proton therapy. Medical Physics. 42: 2462-9. PMID 25979039 DOI: 10.1118/1.4916662  0.679
2015 Grassberger C, Lomax A, Paganetti H. Characterizing a proton beam scanning system for Monte Carlo dose calculation in patients. Physics in Medicine and Biology. 60: 633-45. PMID 25549079 DOI: 10.1088/0031-9155/60/2/633  0.758
2015 Manem V, Grassberger C, Paganetti H. TH-AB-304-10: Modeling Organ Specific Mechanistic Interactions Between Radiation and Chemotherapy Medical Physics. 42: 3703-3703. DOI: 10.1118/1.4926125  0.655
2015 Schuemann J, Giantsoudi D, Grassberger C, Paganetti H. SU-E-T-135: Assessing the Clinical Impact of Approximations in Analytical Dose Calculations for Proton Therapy Medical Physics. 42: 3362-3362. DOI: 10.1118/1.4924496  0.707
2015 Grassberger C, Sharp G, Fintelmann F, Paganetti H, Willers H. SU-E-J-247: Time Evolution of Radiation-Induced Lung Injury After Stereotactic Proton Therapy Medical Physics. 42: 3323-3323. DOI: 10.1118/1.4924333  0.68
2015 Schuemann J, Giantsoudi D, Grassberger C, Moteabbed M, Min CH, Dowdell S, Paganetti H. SP-0111: Dose calculation accuracy in proton therapy Radiotherapy and Oncology. 115. DOI: 10.1016/S0167-8140(15)40109-4  0.66
2015 Grassberger C, Manem V, Eaton B, Yock T, Paganetti H. Predicting Secondary Breast and Lung Malignancy Risk After Combined Chemoradiation Treatment International Journal of Radiation Oncology*Biology*Physics. 93: E508. DOI: 10.1016/J.Ijrobp.2015.07.1845  0.589
2015 Phillips J, Gueorguiev G, Grassberger C, Choi N, Paganetti H, Sharp G. Effects of Excess Breathing Motion on Proton Dose Coverage International Journal of Radiation Oncology*Biology*Physics. 93: E435. DOI: 10.1016/J.Ijrobp.2015.07.1655  0.622
2014 Knopf A, Nill S, Yohannes I, Graeff C, Dowdell S, Kurz C, Sonke JJ, Biegun AK, Lang S, McClelland J, Champion B, Fast M, Wölfelschneider J, Gianoli C, Rucinski A, ... ... Grassberger C, et al. Challenges of radiotherapy: report on the 4D treatment planning workshop 2013. Physica Medica : Pm : An International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (Aifb). 30: 809-15. PMID 25172392 DOI: 10.1016/J.Ejmp.2014.07.341  0.353
2014 Phillips J, Gueorguiev G, Shackleford JA, Grassberger C, Dowdell S, Paganetti H, Sharp GC. Computing proton dose to irregularly moving targets. Physics in Medicine and Biology. 59: 4261-73. PMID 25029239 DOI: 10.1088/0031-9155/59/15/4261  0.627
2014 Schuemann J, Dowdell S, Grassberger C, Min CH, Paganetti H. Site-specific range uncertainties caused by dose calculation algorithms for proton therapy. Physics in Medicine and Biology. 59: 4007-31. PMID 24990623 DOI: 10.1088/0031-9155/59/15/4007  0.682
2014 Grassberger C, Daartz J, Dowdell S, Ruggieri T, Sharp G, Paganetti H. Quantification of proton dose calculation accuracy in the lung. International Journal of Radiation Oncology, Biology, Physics. 89: 424-30. PMID 24726289 DOI: 10.1016/J.Ijrobp.2014.02.023  0.686
2014 Schuemann J, Dowdell S, Grassberger C, Paganetti H. TH-A-19A-06: Site-Specific Comparison of Analytical and Monte Carlo Based Dose Calculations Medical Physics. 41: 534-534. DOI: 10.1118/1.4889539  0.676
2014 Grassberger C, Daartz J, Dowdell S, Ruggieri T, Sharp G, Paganetti H. TH-A-19A-03: Impact of Proton Dose Calculation Method On Delivered Dose to Lung Tumors: Experiments in Thorax Phantom and Planning Study in Patient Cohort Medical Physics. 41: 533-533. DOI: 10.1118/1.4889536  0.706
2014 Dowdell S, Grassberger C, Paganetti H. SU-E-T-292: Sensitivity of Fractionated Lung IMPT Treatments to Setup Uncertainties and Motion Effects Medical Physics. 41: 291-291. DOI: 10.1118/1.4888624  0.634
2014 Schuemann J, Dowdell S, Grassberger C, Min C, Paganetti H. Site-Specific Range Uncertainties Due to by Dose Calculation Algorithms for Proton Therapy International Journal of Radiation Oncology*Biology*Physics. 90: S26. DOI: 10.1016/J.Ijrobp.2014.05.125  0.643
2013 Phillips J, Gueorguiev G, Shackleford J, Grassberger C, Dowdell S, Paganetti H, Sharp G. TU-A-108-06: Computing Proton Dose to Irregularly Moving Targets. Medical Physics. 40: 420. PMID 28518846 DOI: 10.1118/1.4815329  0.626
2013 Dowdell S, Grassberger C, Paganetti H. Four-dimensional Monte Carlo simulations demonstrating how the extent of intensity-modulation impacts motion effects in proton therapy lung treatments. Medical Physics. 40: 121713. PMID 24320499 DOI: 10.1118/1.4829500  0.649
2013 Giantsoudi D, Grassberger C, Craft D, Niemierko A, Trofimov A, Paganetti H. Linear energy transfer-guided optimization in intensity modulated proton therapy: feasibility study and clinical potential. International Journal of Radiation Oncology, Biology, Physics. 87: 216-22. PMID 23790771 DOI: 10.1016/J.Ijrobp.2013.05.013  0.627
2013 Dowdell S, Grassberger C, Sharp GC, Paganetti H. Interplay effects in proton scanning for lung: a 4D Monte Carlo study assessing the impact of tumor and beam delivery parameters. Physics in Medicine and Biology. 58: 4137-56. PMID 23689035 DOI: 10.1088/0031-9155/58/12/4137  0.679
2013 Zeng C, Giantsoudi D, Grassberger C, Goldberg S, Niemierko A, Paganetti H, Efstathiou JA, Trofimov A. Maximizing the biological effect of proton dose delivered with scanned beams via inhomogeneous daily dose distributions. Medical Physics. 40: 051708. PMID 23635256 DOI: 10.1118/1.4801897  0.686
2013 Carabe A, España S, Grassberger C, Paganetti H. Clinical consequences of relative biological effectiveness variations in proton radiotherapy of the prostate, brain and liver. Physics in Medicine and Biology. 58: 2103-17. PMID 23470339 DOI: 10.1088/0031-9155/58/7/2103  0.635
2013 Grassberger C, Dowdell S, Lomax A, Sharp G, Shackleford J, Choi N, Willers H, Paganetti H. Motion interplay as a function of patient parameters and spot size in spot scanning proton therapy for lung cancer. International Journal of Radiation Oncology, Biology, Physics. 86: 380-6. PMID 23462423 DOI: 10.1016/J.Ijrobp.2013.01.024  0.65
2013 Dowdell S, Grassberger C, Paganetti H. TU-A-108-08: Comparison of Full Intensity Modulated and Single Field Uniform Dose Proton Beam Scanning Lung Treatments Medical Physics. 40: 421-421. DOI: 10.1118/1.4815331  0.696
2013 Dowdell S, Grassberger C, Sharp G, Paganetti H. TU-A-108-02: A 4D Monte Carlo Study Quantifying Changes in the Interplay Effect as a Function of Treatment Delivery Parameters in Proton Beam Scanning for Lung Medical Physics. 40: 419-420. DOI: 10.1118/1.4815325  0.696
2013 Grassberger C, Daartz J, Dowdell S, Verburg J, Sharp G, Paganetti H. MO-G-137-02: Experimental Validation of Clinical as Well as Monte Carlo Dose Calculation for Proton Therapy of Lung Cancer Patients Medical Physics. 40: 416-416. DOI: 10.1118/1.4815315  0.695
2013 Grassberger C, Dowdell S, Sharp G, Paganetti H. SU-F-500-04: Motion Mitigation in Active Scanning Proton Therapy for Lung Cancer: A 4D Monte Carlo Study Medical Physics. 40: 383-383. DOI: 10.1118/1.4815194  0.669
2013 Giantsoudi D, Clasie B, Grassberger C, Dowdell S, Depauw N, Madden T, Kooy H, Paganetti H. SU-E-T-512: Monte Carlo Dose Verification of Pencil Beam Scanning Proton Therapy Medical Physics. 40: 323-323. DOI: 10.1118/1.4814941  0.676
2012 Zeng C, Giantsoudi D, Grassberger C, Goldberg S, Niemierko A, Paganetti H, Trofimov A. SU-E-T-552: Maximizing the Biological Effect of Proton Dose Delivered with Scanned Beam. Medical Physics. 39: 3832. PMID 28518512 DOI: 10.1118/1.4735641  0.674
2012 Schuemann J, Shin J, Perl J, Grassberger C, Verburg J, Faddegon B, Paganetti H. SU-E-T-500: Pencil-Beam versus Monte Carlo Based Dose Calculation for Proton Therapy Patients with Complex Geometries. Clinical Use of the TOPAS Monte Carlo System. Medical Physics. 39: 3820. PMID 28518479 DOI: 10.1118/1.4735589  0.672
2012 Grassberger C, Shackleford J, Sharp G, Paganetti H. TH-C-BRB-08: Four-Dimensional Monte Carlo Simulations of Lung Cancer Patients Treated with Proton Beam Scanning to Assess Interplay Effects Medical Physics. 39: 3998-3998. DOI: 10.1118/1.4736311  0.667
2012 Giantsoudi D, Grassberger C, Craft D, Niemierko A, Trofimov A, Paganetti H. TH-C-213AB-11: LET-Guided Biological Optimization in IMPT Medical Physics. 39: 3995-3996. DOI: 10.1118/1.4736300  0.655
2012 Paganetti H, Schuemann J, Grassberger C, Verburg J, Giantsoudi D, Moteabbed M, Min C, Testa M, Faddegon B, Perl J. Advanced Dose Calculation to Reduce Uncertainties in Treatment Planning and Delivery for Proton Therapy Patients International Journal of Radiation Oncology Biology Physics. 84. DOI: 10.1016/J.Ijrobp.2012.07.352  0.69
2012 Giantsoudi D, Grassberger C, Craft D, Niemierko A, Trofimov AV, Paganetti H. LET Guided Biological Optimization in IMPT: Implications on RBE Value International Journal of Radiation Oncology Biology Physics. 84. DOI: 10.1016/J.Ijrobp.2012.07.2261  0.625
2011 Grassberger C, Paganetti H. Elevated LET components in clinical proton beams. Physics in Medicine and Biology. 56: 6677-91. PMID 21965268 DOI: 10.1088/0031-9155/56/20/011  0.639
2011 Grassberger C, Trofimov A, Lomax A, Paganetti H. Variations in linear energy transfer within clinical proton therapy fields and the potential for biological treatment planning. International Journal of Radiation Oncology, Biology, Physics. 80: 1559-66. PMID 21163588 DOI: 10.1016/J.Ijrobp.2010.10.027  0.745
2011 Paganetti H, Grassberger C, Carabe-Fernandez A. TU-G-BRA-01: Clinical Significance of RBE Variations in Proton and Carbon Ion Therapy (an Overview/introduction to the Problem) Medical Physics. 38: 3777-3777. DOI: 10.1118/1.3613216  0.688
2011 Grassberger C, Paganetti H. MO-G-BRC-05: Impact of Secondary Particles on Linear Energy Transfer for Biological Treatment Planning in Proton Therapy Medical Physics. 38: 3737-3737. DOI: 10.1118/1.3613062  0.634
2011 Carabe-Fernandez A, Grassberger C, Carlson D, Stewart R, Frese M, Gerweck L, Skarsgard L, Wouters B, Paganetti H. SU-E-T-05: Biophysical Modeling Intercomparison of Proton Radiation Effectiveness Medical Physics. 38: 3486-3486. DOI: 10.1118/1.3611955  0.657
2010 Grassberger C, Trofimov A, Paganetti H. MO‐E‐BRB‐02: Biologically Optimized Treatment Planning for Proton Therapy: Monte Carlo Calculated Linear Energy Transfer Distributions in Patients Medical Physics. 37: 3355-3355. DOI: 10.1118/1.3469112  0.685
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