☰

Alexander Fletcher, DPhil - Publications

Affiliations: 
Mathematics Oxford University UK 
Area:
Mathematical biology
Website:
https://alexfletcher.github.io/about/
Tree Info Similar researchers PubMed Report error

41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Cammarota C, Dawney NS, Bellomio PM, Jüng M, Fletcher AG, Finegan TM, Bergstralh DT. The mechanical influence of densification on epithelial architecture. Plos Computational Biology. 20: e1012001. PMID 38557605 DOI: 10.1371/journal.pcbi.1012001  0.312
2023 Cooper FR, Baker RE, Bernabeu MO, Bordas R, Bowler L, Bueno-Orovio A, Byrne HM, Carapella V, Cardone-Noott L, Jonatha C, Dutta S, Evans BD, Fletcher AG, Grogan JA, Guo W, et al. Chaste: Cancer, Heart and Soft Tissue Environment. Journal of Open Source Software. 5: 1848. PMID 37192932 DOI: 10.21105/joss.01848  0.517
2022 Johnson CGM, Fletcher AG, Soyer OS. ChemChaste: Simulating spatially inhomogeneous biochemical reaction-diffusion systems for modeling cell-environment feedbacks. Gigascience. 11. PMID 35715874 DOI: 10.1093/gigascience/giac051  0.3
2022 Nestor-Bergmann A, Blanchard GB, Hervieux N, Fletcher AG, Étienne J, Sanson B. Adhesion-regulated junction slippage controls cell intercalation dynamics in an Apposed-Cortex Adhesion Model. Plos Computational Biology. 18: e1009812. PMID 35089922 DOI: 10.1371/journal.pcbi.1009812  0.332
2021 Fletcher AG, Osborne JM. Seven challenges in the multiscale modeling of multicellular tissues. Wires Mechanisms of Disease. 14: e1527. PMID 35023326 DOI: 10.1002/wsbm.1527  0.328
2020 Ward D, Montes Olivas S, Fletcher A, Homer M, Marucci L. Cross-talk between Hippo and Wnt signalling pathways in intestinal crypts: Insights from an agent-based model. Computational and Structural Biotechnology Journal. 18: 230-240. PMID 33489001 DOI: 10.1016/J.Csbj.2019.12.015  0.368
2020 Ruske LJ, Kursawe J, Tsakiridis A, Wilson V, Fletcher A, Blythe RA, Schumacher LJ. Coupled differentiation and division of embryonic stem cells inferred from clonal snapshots. Physical Biology. PMID 32585646 DOI: 10.1088/1478-3975/Aba041  0.344
2020 Grimes DR, Fletcher AG. Close Encounters of the Cell Kind: The Impact of Contact Inhibition on Tumour Growth and Cancer Models. Bulletin of Mathematical Biology. 82: 20. PMID 31970500 DOI: 10.1007/s11538-019-00677-y  0.345
2020 Cooper F, Baker R, Bernabeu M, Bordas R, Bowler L, Bueno-Orovio A, Byrne H, Carapella V, Cardone-Noott L, Cooper J, Dutta S, Evans B, Fletcher A, Grogan J, Guo W, et al. Chaste: Cancer, Heart and Soft Tissue Environment Journal of Open Source Software. 5: 1848. DOI: 10.21105/joss.01848  0.362
2019 Scott JG, Maini PK, Anderson ARA, Fletcher AG. Inferring Tumour Proliferative Organisation from Phylogenetic Tree Measures in a Computational Model. Systematic Biology. PMID 31665523 DOI: 10.1093/Sysbio/Syz070  0.645
2019 Parker A, Vaux L, Patterson AM, Modasia A, Muraro D, Fletcher AG, Byrne HM, Maini PK, Watson AJM, Pin C. Elevated apoptosis impairs epithelial cell turnover and shortens villi in TNF-driven intestinal inflammation. Cell Death & Disease. 10: 108. PMID 30728350 DOI: 10.1038/s41419-018-1275-5  0.47
2019 Scott JG, Dhawan A, Hjelmeland A, Lathia J, Chumakova A, Hitomi M, Fletcher AG, Maini PK, Anderson ARA. Recasting the Cancer Stem Cell Hypothesis: Unification Using a Continuum Model of Microenvironmental Forces Current Stem Cell Reports. 5: 22-30. DOI: 10.1007/S40778-019-0153-0  0.637
2018 Muraro D, Parker A, Vaux L, Filippi S, Almet AA, Fletcher AG, Watson AJM, Pin C, Maini PK, Byrne HM. Chronic TNFα-driven injury delays cell migration to villi in the intestinal epithelium. Journal of the Royal Society, Interface. 15. PMID 30068555 DOI: 10.1098/rsif.2018.0037  0.508
2018 Blanchard GB, Fletcher AG, Schumacher LJ. The devil is in the mesoscale: mechanical and behavioural heterogeneity in collective cell movement. Seminars in Cell & Developmental Biology. PMID 29940338 DOI: 10.1016/j.semcdb.2018.06.003  0.337
2018 Kursawe J, Baker RE, Fletcher AG. Approximate Bayesian computation reveals the importance of repeated measurements for parameterising cell-based models of growing tissues. Journal of Theoretical Biology. PMID 29391171 DOI: 10.1016/j.jtbi.2018.01.020  0.33
2017 Maclaren OJ, Parker A, Pin C, Carding SR, Watson AJM, Fletcher AG, Byrne HM, Maini PK. A hierarchical Bayesian model for understanding the spatiotemporal dynamics of the intestinal epithelium. Plos Computational Biology. 13: e1005688. PMID 28753601 DOI: 10.1371/journal.pcbi.1005688  0.557
2017 Fletcher AG, Cooper F, Baker RE. Mechanocellular models of epithelial morphogenesis. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 372. PMID 28348253 DOI: 10.1098/rstb.2015.0519  0.4
2017 Osborne JM, Fletcher AG, Pitt-Francis JM, Maini PK, Gavaghan DJ. Comparing individual-based approaches to modelling the self-organization of multicellular tissues. Plos Computational Biology. 13: e1005387. PMID 28192427 DOI: 10.1371/journal.pcbi.1005387  0.567
2016 Parker A, Maclaren OJ, Fletcher AG, Muraro D, Kreuzaler PA, Byrne HM, Maini PK, Watson AJ, Pin C. Cell proliferation within small intestinal crypts is the principal driving force for cell migration on villi. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 27811059 DOI: 10.1096/fj.201601002  0.521
2016 Scott JG, Fletcher AG, Anderson AR, Maini PK. Spatial Metrics of Tumour Vascular Organisation Predict Radiation Efficacy in a Computational Model. Plos Computational Biology. 12: e1004712. PMID 26800503 DOI: 10.1371/Journal.Pcbi.1004712  0.668
2015 Maclaren OJ, Byrne HM, Fletcher AG, Maini PK. Models, measurement and inference in epithelial tissue dynamics. Mathematical Biosciences and Engineering : Mbe. 12: 1321-40. PMID 26775866 DOI: 10.3934/mbe.2015.12.1321  0.512
2015 Kursawe J, Brodskiy PA, Zartman JJ, Baker RE, Fletcher AG. Capabilities and Limitations of Tissue Size Control through Passive Mechanical Forces. Plos Computational Biology. 11: e1004679. PMID 26713738 DOI: 10.1371/Journal.Pcbi.1004679  0.304
2015 Nichol D, Jeavons P, Fletcher AG, Bonomo RA, Maini PK, Paul JL, Gatenby RA, Anderson AR, Scott JG. Steering Evolution with Sequential Therapy to Prevent the Emergence of Bacterial Antibiotic Resistance. Plos Computational Biology. 11: e1004493. PMID 26360300 DOI: 10.1371/Journal.Pcbi.1004493  0.644
2015 Narciso C, Wu Q, Brodskiy P, Garston G, Baker R, Fletcher A, Zartman J. Patterning of wound-induced intercellular Ca(2+) flashes in a developing epithelium. Physical Biology. 12: 056005. PMID 26331891 DOI: 10.1088/1478-3975/12/5/056005  0.305
2015 Fletcher AG, Murray PJ, Maini PK. Multiscale modelling of intestinal crypt organization and carcinogenesis Mathematical Models and Methods in Applied Sciences. 25: 2563-2585. DOI: 10.1142/S0218202515400187  0.448
2014 Scott JG, Fletcher AG, Maini PK, Anderson AR, Gerlee P. A filter-flow perspective of haematogenous metastasis offers a non-genetic paradigm for personalised cancer therapy. European Journal of Cancer (Oxford, England : 1990). 50: 3068-75. PMID 25306188 DOI: 10.1016/J.Ejca.2014.08.019  0.665
2014 Fletcher AG, Osterfield M, Baker RE, Shvartsman SY. Vertex models of epithelial morphogenesis. Biophysical Journal. 106: 2291-304. PMID 24896108 DOI: 10.1016/J.Bpj.2013.11.4498  0.409
2014 Bloch K, Smith H, van Hamel Parsons V, Gavaghan D, Kelly C, Fletcher A, Maini P, Callaghan R. Metabolic alterations during the growth of tumour spheroids. Cell Biochemistry and Biophysics. 68: 615-28. PMID 24037715 DOI: 10.1007/S12013-013-9757-7  0.458
2013 Rosser G, Fletcher AG, Wilkinson DA, de Beyer JA, Yates CA, Armitage JP, Maini PK, Baker RE. Novel methods for analysing bacterial tracks reveal persistence in Rhodobacter sphaeroides. Plos Computational Biology. 9: e1003276. PMID 24204227 DOI: 10.1371/Journal.Pcbi.1003276  0.385
2013 Fletcher AG, Osborne JM, Maini PK, Gavaghan DJ. Implementing vertex dynamics models of cell populations in biology within a consistent computational framework. Progress in Biophysics and Molecular Biology. 113: 299-326. PMID 24120733 DOI: 10.1016/j.pbiomolbio.2013.09.003  0.572
2013 Vincent JP, Fletcher AG, Baena-Lopez LA. Mechanisms and mechanics of cell competition in epithelia. Nature Reviews. Molecular Cell Biology. 14: 581-91. PMID 23942450 DOI: 10.1038/nrm3639  0.32
2013 Scott JG, Gerlee P, Basanta D, Fletcher AG, Maini PK, Anderson ARA. Mathematical modeling of the metastatic process Experimental Metastasis: Modeling and Analysis. 189-208. DOI: 10.1007/978-94-007-7835-1_9  0.607
2012 Dello Ioio R, Galinha C, Fletcher AG, Grigg SP, Molnar A, Willemsen V, Scheres B, Sabatini S, Baulcombe D, Maini PK, Tsiantis M. A PHABULOSA/cytokinin feedback loop controls root growth in Arabidopsis. Current Biology : Cb. 22: 1699-704. PMID 22902752 DOI: 10.1016/J.Cub.2012.07.005  0.441
2012 Mirams GR, Fletcher AG, Maini PK, Byrne HM. A theoretical investigation of the effect of proliferation and adhesion on monoclonal conversion in the colonic crypt. Journal of Theoretical Biology. 312: 143-56. PMID 22902425 DOI: 10.1016/j.jtbi.2012.08.002  0.551
2012 Fletcher AG, Breward CJ, Jonathan Chapman S. Mathematical modeling of monoclonal conversion in the colonic crypt. Journal of Theoretical Biology. 300: 118-33. PMID 22285553 DOI: 10.1016/j.jtbi.2012.01.021  0.66
2012 Dunn SJ, Fletcher AG, Chapman SJ, Gavaghan DJ, Osborne JM. Modelling the role of the basement membrane beneath a growing epithelial monolayer. Journal of Theoretical Biology. 298: 82-91. PMID 22200542 DOI: 10.1016/j.jtbi.2011.12.013  0.327
2011 Murray PJ, Walter A, Fletcher AG, Edwards CM, Tindall MJ, Maini PK. Comparing a discrete and continuum model of the intestinal crypt. Physical Biology. 8: 026011. PMID 21411869 DOI: 10.1088/1478-3975/8/2/026011  0.549
2010 Osborne JM, Walter A, Kershaw SK, Mirams GR, Fletcher AG, Pathmanathan P, Gavaghan D, Jensen OE, Maini PK, Byrne HM. A hybrid approach to multi-scale modelling of cancer. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 368: 5013-28. PMID 20921009 DOI: 10.1098/Rsta.2010.0173  0.588
2009 van Leeuwen IM, Mirams GR, Walter A, Fletcher A, Murray P, Osborne J, Varma S, Young SJ, Cooper J, Doyle B, Pitt-Francis J, Momtahan L, Pathmanathan P, Whiteley JP, Chapman SJ, et al. An integrative computational model for intestinal tissue renewal. Cell Proliferation. 42: 617-36. PMID 19622103 DOI: 10.1111/J.1365-2184.2009.00627.X  0.619
2009 Pathmanathan P, Cooper J, Fletcher A, Mirams G, Murray P, Osborne J, Pitt-Francis J, Walter A, Chapman SJ. A computational study of discrete mechanical tissue models Physical Biology. 6. PMID 19369704 DOI: 10.1088/1478-3975/6/3/036001  0.477
2009 Pitt-Francis J, Pathmanathan P, Bernabeu MO, Bordas R, Cooper J, Fletcher AG, Mirams GR, Murray P, Osborne JM, Walter A, Chapman SJ, Garny A, van Leeuwen IMM, Maini PK, Rodríguez B, et al. Chaste: A test-driven approach to software development for biological modelling Computer Physics Communications. 180: 2452-2471. DOI: 10.1016/j.cpc.2009.07.019  0.415
Show low-probability matches.