Anthony S. Basile - Publications

Affiliations: 
Allergan LLC 
Area:
Spasticity, Pain

134 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Warnock KT, Yang AR, Yi HS, June HL, Kelly T, Basile AS, Skolnick P, June HL. Amitifadine, a triple monoamine uptake inhibitor, reduces binge drinking and negative affect in an animal model of co-occurring alcoholism and depression symptomatology. Pharmacology, Biochemistry, and Behavior. 103: 111-8. PMID 22884707 DOI: 10.1016/j.pbb.2012.07.014  1
2012 Yang AR, Yi HS, Warnock KT, Mamczarz J, June HL, Mallick N, Krieter PA, Tonelli L, Skolnick P, Basile AS, June HL. Effects of the triple monoamine uptake inhibitor DOV 102,677 on alcohol-motivated responding and antidepressant activity in alcohol-preferring (P) rats. Alcoholism, Clinical and Experimental Research. 36: 863-73. PMID 22150508 DOI: 10.1111/j.1530-0277.2011.01671.x  1
2009 Nicholson KL, Balster RL, Golembiowska K, Kowalska M, Tizzano JP, Skolnick P, Basile AS. Preclinical evaluation of the abuse potential of the analgesic bicifadine. The Journal of Pharmacology and Experimental Therapeutics. 330: 236-48. PMID 19357320 DOI: 10.1124/jpet.109.150540  1
2008 Berezhnoy D, Gravielle MC, Downing S, Kostakis E, Basile AS, Skolnick P, Gibbs TT, Farb DH. Pharmacological Properties of DOV 315,090, an ocinaplon metabolite. Bmc Pharmacology. 8: 11. PMID 18554397 DOI: 10.1186/1471-2210-8-11  1
2008 Tizzano JP, Stribling DS, Perez-Tilve D, Strack A, Frassetto A, Chen RZ, Fong TM, Shearman L, Krieter PA, Tschöp MH, Skolnick P, Basile AS. The triple uptake inhibitor (1R,5S)-(+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0] hexane hydrochloride (DOV 21947) reduces body weight and plasma triglycerides in rodent models of diet-induced obesity. The Journal of Pharmacology and Experimental Therapeutics. 324: 1111-26. PMID 18089843 DOI: 10.1124/jpet.107.133132  1
2007 McMillen BA, Shank JE, Jordan KB, Williams HL, Basile AS. Effect of DOV 102,677 on the volitional consumption of ethanol by Myers' high ethanol-preferring rat. Alcoholism, Clinical and Experimental Research. 31: 1866-71. PMID 17908267 DOI: 10.1111/j.1530-0277.2007.00513.x  1
2007 Wu S, Basile AS, Barger SW. Induction of serine racemase expression and D-serine release from microglia by secreted amyloid precursor protein (sAPP). Current Alzheimer Research. 4: 243-51. PMID 17627481 DOI: 10.2174/156720507781077241  1
2007 Skolnick P, Basile AS. Triple reuptake inhibitors ("broad spectrum" antidepressants). Cns & Neurological Disorders Drug Targets. 6: 141-9. PMID 17430151 DOI: 10.2174/187152707780363285  1
2007 Basile AS, Janowsky A, Golembiowska K, Kowalska M, Tam E, Benveniste M, Popik P, Nikiforuk A, Krawczyk M, Nowak G, Krieter PA, Lippa AS, Skolnick P, Koustova E. Characterization of the antinociceptive actions of bicifadine in models of acute, persistent, and chronic pain. The Journal of Pharmacology and Experimental Therapeutics. 321: 1208-25. PMID 17325229 DOI: 10.1124/jpet.106.116483  1
2006 Popik P, Kostakis E, Krawczyk M, Nowak G, Szewczyk B, Krieter P, Chen Z, Russek SJ, Gibbs TT, Farb DH, Skolnick P, Lippa AS, Basile AS. The anxioselective agent 7-(2-chloropyridin-4-yl)pyrazolo-[1,5-a]-pyrimidin-3-yl](pyridin-2-yl)methanone (DOV 51892) is more efficacious than diazepam at enhancing GABA-gated currents at alpha1 subunit-containing GABAA receptors. The Journal of Pharmacology and Experimental Therapeutics. 319: 1244-52. PMID 16971504 DOI: 10.1124/jpet.106.107201  1
2006 Skolnick P, Krieter P, Tizzano J, Basile A, Popik P, Czobor P, Lippa A. Preclinical and clinical pharmacology of DOV 216,303, a "triple" reuptake inhibitor. Cns Drug Reviews. 12: 123-34. PMID 16958986 DOI: 10.1111/j.1527-3458.2006.00123.x  1
2006 Popik P, Krawczyk M, Golembiowska K, Nowak G, Janowsky A, Skolnick P, Lippa A, Basile AS. Pharmacological profile of the "triple" monoamine neurotransmitter uptake inhibitor, DOV 102,677. Cellular and Molecular Neurobiology. 26: 857-73. PMID 16636898 DOI: 10.1007/s10571-006-9012-5  1
2006 Skolnick P, Basile AS. Triple reuptake inhibitors as antidepressants Drug Discovery Today: Therapeutic Strategies. 3: 489-494. DOI: 10.1016/j.ddstr.2006.10.010  1
2006 Basile AS, Lippa AS, Skolnick P. GABAA receptor modulators as anxioselective anxiolytics Drug Discovery Today: Therapeutic Strategies. 3: 475-481. DOI: 10.1016/j.ddstr.2006.10.009  1
2004 Seeger T, Fedorova I, Zheng F, Miyakawa T, Koustova E, Gomeza J, Basile AS, Alzheimer C, Wess J. M2 muscarinic acetylcholine receptor knock-out mice show deficits in behavioral flexibility, working memory, and hippocampal plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10117-27. PMID 15537882 DOI: 10.1523/JNEUROSCI.3581-04.2004  1
2004 Basile AS, Lippa AS, Skolnick P. Anxioselective anxiolytics: can less be more? European Journal of Pharmacology. 500: 441-51. PMID 15464051 DOI: 10.1016/j.ejphar.2004.07.043  1
2004 Wu SZ, Bodles AM, Porter MM, Griffin WS, Basile AS, Barger SW. Induction of serine racemase expression and D-serine release from microglia by amyloid beta-peptide. Journal of Neuroinflammation. 1: 2. PMID 15285800 DOI: 10.1186/1742-2094-1-2  1
2004 Bartus RT, Emerich D, Snodgrass-Belt P, Fu K, Salzberg-Brenhouse H, Lafreniere D, Novak L, Lo ES, Cooper T, Basile AS. A pulmonary formulation of L-dopa enhances its effectiveness in a rat model of Parkinson's disease. The Journal of Pharmacology and Experimental Therapeutics. 310: 828-35. PMID 15039453 DOI: 10.1124/jpet.103.064121  1
2003 Yamada M, Basile AS, Fedorova I, Zhang W, Duttaroy A, Cui Y, Lamping KG, Faraci FM, Deng CX, Wess J. Novel insights into M5 muscarinic acetylcholine receptor function by the use of gene targeting technology. Life Sciences. 74: 345-53. PMID 14607263 DOI: 10.1016/j.lfs.2003.09.022  1
2003 Fink-Jensen A, Fedorova I, Wörtwein G, Woldbye DP, Rasmussen T, Thomsen M, Bolwig TG, Knitowski KM, McKinzie DL, Yamada M, Wess J, Basile A. Role for M5 muscarinic acetylcholine receptors in cocaine addiction. Journal of Neuroscience Research. 74: 91-6. PMID 13130510 DOI: 10.1002/jnr.10728  1
2003 Fedorova IM, Jacobson MA, Basile A, Jacobson KA. Behavioral characterization of mice lacking the A3 adenosine receptor: sensitivity to hypoxic neurodegeneration. Cellular and Molecular Neurobiology. 23: 431-47. PMID 12825837 DOI: 10.1023/A:1023601007518  1
2003 Salzberg-Brenhouse HC, Chen EY, Emerich DF, Baldwin S, Hogeland K, Ranelli S, Lafreniere D, Perdomo B, Novak L, Kladis T, Fu K, Basile AS, Kordower JH, Bartus RT. Inhibitors of cyclooxygenase-2, but not cyclooxygenase-1 provide structural and functional protection against quinolinic acid-induced neurodegeneration. The Journal of Pharmacology and Experimental Therapeutics. 306: 218-28. PMID 12676885 DOI: 10.1124/jpet.103.049700  1
2003 Bartus RT, Emerich DF, Hotz J, Blaustein M, Dean RL, Perdomo B, Basile AS. Vivitrex®, an Injectable, Extended-Release Formulation of Naltrexone, Provides Pharmacokinetic and Pharmacodynamic Evidence of Efficacy for I Month in Rats Neuropsychopharmacology. 28: 1973-1982.  1
2002 Sei Y, Basile AS. A murine model of retroviral encephalopathy. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit9.8. PMID 18428573 DOI: 10.1002/0471142301.ns0908s17  1
2002 Duttaroy A, Gomeza J, Gan JW, Siddiqui N, Basile AS, Harman WD, Smith PL, Felder CC, Levey AI, Wess J. Evaluation of muscarinic agonist-induced analgesia in muscarinic acetylcholine receptor knockout mice. Molecular Pharmacology. 62: 1084-93. PMID 12391271 DOI: 10.1124/mol.62.5.1084  1
2002 Basile AS, Fedorova I, Zapata A, Liu X, Shippenberg T, Duttaroy A, Yamada M, Wess J. Deletion of the M5 muscarinic acetylcholine receptor attenuates morphine reinforcement and withdrawal but not morphine analgesia. Proceedings of the National Academy of Sciences of the United States of America. 99: 11452-7. PMID 12154229 DOI: 10.1073/pnas.162371899  1
2002 Zhang W, Yamada M, Gomeza J, Basile AS, Wess J. Multiple muscarinic acetylcholine receptor subtypes modulate striatal dopamine release, as studied with M1-M5 muscarinic receptor knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 6347-52. PMID 12151512  1
2002 Basile AS. Direct and indirect enhancement of GABAergic neurotransmission by ammonia: implications for the pathogenesis of hyperammonemic syndromes. Neurochemistry International. 41: 115-22. PMID 12020612 DOI: 10.1016/S0197-0186(02)00032-3  1
2002 Espey MG, Basile AS, Heaton RK, Ellis RJ. Increased glutamate in CSF and plasma of patients with HIV dementia. Neurology. 58: 1439; author reply 1. PMID 12011305  1
2002 Zhang W, Basile AS, Gomeza J, Volpicelli LA, Levey AI, Wess J. Characterization of central inhibitory muscarinic autoreceptors by the use of muscarinic acetylcholine receptor knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 1709-17. PMID 11880500  1
2002 Casellas P, Galiegue S, Basile AS. Peripheral benzodiazepine receptors and mitochondrial function. Neurochemistry International. 40: 475-86. PMID 11850104 DOI: 10.1016/S0197-0186(01)00118-8  1
2002 Basile AS. Neurochemistry International: Preface Neurochemistry International. 40: 467. DOI: 10.1016/S0197-0186(01)00116-4  1
2001 Basile AS, Mullen K. Preclinical models of hepatic encephalopathy. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit9.3. PMID 18428551 DOI: 10.1002/0471142301.ns0903s08  1
2001 Basile A. Saturation assays of radioligand binding to receptors and their allosteric modulatory sites Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit7.6. PMID 18428532  1
2001 Laposky AD, Homanics GE, Basile A, Mendelson WB. Deletion of the GABA(A) receptor beta 3 subunit eliminates the hypnotic actions of oleamide in mice. Neuroreport. 12: 4143-7. PMID 11742254  1
2001 Basile AS, Koustova E, Ioan P, Rizzoli S, Rogawski MA, Usherwood PN. IgG isolated from LP-BM5 infected mouse brain activates ionotropic glutamate receptors. Neurobiology of Disease. 8: 1069-81. PMID 11741402 DOI: 10.1006/nbdi.2001.0442  1
2001 Mendelson WB, Basile AS. The hypnotic actions of the fatty acid amide, oleamide. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 25: S36-9. PMID 11682271 DOI: 10.1016/S0893-133X(01)00341-4  1
2001 Fedorova I, Hashimoto A, Fecik RA, Hedrick MP, Hanus LO, Boger DL, Rice KC, Basile AS. Behavioral evidence for the interaction of oleamide with multiple neurotransmitter systems. The Journal of Pharmacology and Experimental Therapeutics. 299: 332-42. PMID 11561096  1
2001 Koustova E, Sei Y, Fossom L, Wei ML, Usherwood PN, Keele NB, Rogawski MA, Basile AS. LP-BM5 virus-infected mice produce activating autoantibodies to the AMPA receptor. The Journal of Clinical Investigation. 107: 737-44. PMID 11254673 DOI: 10.1172/JCI11500  1
2001 Hernández-Sánchez C, Basile AS, Fedorova I, Arima H, Stannard B, Fernandez AM, Ito Y, LeRoith D. Mice transgenically overexpressing sulfonylurea receptor 1 in forebrain resist seizure induction and excitotoxic neuron death. Proceedings of the National Academy of Sciences of the United States of America. 98: 3549-54. PMID 11248115 DOI: 10.1073/pnas.051012898  1
2001 Barger SW, Basile AS. Activation of microglia by secreted amyloid precursor protein evokes release of glutamate by cystine exchange and attenuates synaptic function. Journal of Neurochemistry. 76: 846-54. PMID 11158256 DOI: 10.1046/j.1471-4159.2001.00075.x  1
2000 Koustova E, Sei Y, McCarty T, Espey MG, Ming R, Morse HC, Basile AS. Accelerated development of neurochemical and behavioral deficits in LP-BM5 infected mice with targeted deletions of the IFN-gamma gene. Journal of Neuroimmunology. 108: 112-21. PMID 10900344 DOI: 10.1016/S0165-5728(00)00258-7  1
2000 Iida R, Saito K, Yamada K, Basile AS, Sekikawa K, Takemura M, Fujii H, Wada H, Seishima M, Nabeshima T. Suppression of neurocognitive damage in LP-BM5-infected mice with a targeted deletion of the TNF-alpha gene. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 14: 1023-31. PMID 10783158  1
1999 Mendelson WB, Basile AS. The hypnotic actions of oleamide are blocked by a cannabinoid receptor antagonist. Neuroreport. 10: 3237-9. PMID 10574567  1
1999 Espey MG, Ellis RJ, Heaton RK, Basile AS. Relevance of glutamate levels in the CSF of patients with HIV-1-associated dementia complex. Neurology. 53: 1144-5. PMID 10496286  1
1999 Kustova Y, Grinberg A, Basile AS. Increased blood-brain barrier permeability in LP-BM5 infected mice is mediated by neuroexcitatory mechanisms. Brain Research. 839: 153-63. PMID 10482808 DOI: 10.1016/S0006-8993(99)01734-5  1
1999 Allen JW, Ivanova SA, Fan L, Espey MG, Basile AS, Faden AI. Group II metabotropic glutamate receptor activation attenuates traumatic neuronal injury and improves neurological recovery after traumatic brain injury. The Journal of Pharmacology and Experimental Therapeutics. 290: 112-20. PMID 10381766  1
1999 Hanus LO, Fales HM, Spande TF, Basile AS. A gas chromatographic-mass spectral assay for the quantitative determination of oleamide in biological fluids. Analytical Biochemistry. 270: 159-66. PMID 10328778 DOI: 10.1006/abio.1999.4083  1
1999 Basile AS, Brichta AM, Harris BD, Morse D, Coling D, Skolnick P. Dizocilpine attenuates streptomycin-induced vestibulotoxicity in rats. Neuroscience Letters. 265: 71-4. PMID 10327171 DOI: 10.1016/S0304-3940(99)00050-6  1
1999 Basile AS, Hanus L, Mendelson WB. Characterization of the hypnotic properties of oleamide. Neuroreport. 10: 947-51. PMID 10321465  1
1999 Espey MG, Basile AS. Glutamate augments retrovirus-induced immunodeficiency through chronic stimulation of the hypothalamic-pituitary- adrenal axis. Journal of Immunology (Baltimore, Md. : 1950). 162: 4998-5002. PMID 10202048  1
1999 Sei Y, Gallagher KL, Basile AS. Skeletal muscle type ryanodine receptor is involved in calcium signaling in human B lymphocytes. The Journal of Biological Chemistry. 274: 5995-6002. PMID 10026226 DOI: 10.1074/jbc.274.9.5995  1
1999 Segal JA, Harris BD, Kustova Y, Basile A, Skolnick P. Aminoglycoside neurotoxicity involves NMDA receptor activation. Brain Research. 815: 270-7. PMID 9878779 DOI: 10.1016/S0006-8993(98)01123-8  1
1999 Harris BD, Segal JA, Kustova Y, Basile A, Skolnick P. Aminoglycoside neurotoxicity involves N-methyl-D-aspartate receptor activation Critical Care Medicine. 27: A104.  1
1998 Kustova Y, Espey MG, Sung EG, Morse D, Sei Y, Basile AS. Evidence of neuronal degeneration in C57B1/6 mice infected with the LP-BM5 leukemia retrovirus mixture. Molecular and Chemical Neuropathology / Sponsored by the International Society For Neurochemistry and the World Federation of Neurology and Research Groups On Neurochemistry and Cerebrospinal Fluid. 35: 39-59. PMID 10343970  1
1998 Jones EA, Basile AS. Does ammonia contribute to increased GABA-ergic neurotransmission in liver failure? Metabolic Brain Disease. 13: 351-60. PMID 10206826 DOI: 10.1023/A:1020693026810  1
1998 Kustova Y, Sei Y, Morse HC, Basile AS. The influence of a targeted deletion of the IFNgamma gene on emotional behaviors. Brain, Behavior, and Immunity. 12: 308-24. PMID 10080860 DOI: 10.1006/brbi.1998.0546  1
1998 Espey MG, Kustova Y, Sei Y, Basile AS. Extracellular glutamate levels are chronically elevated in the brains of LP-BM5-infected mice: a mechanism of retrovirus-induced encephalopathy. Journal of Neurochemistry. 71: 2079-87. PMID 9798933  1
1998 Kustova Y, Ha JH, Espey MG, Sei Y, Morse D, Basile AS. The pattern of neurotransmitter alterations in LP-BM5 infected mice is consistent with glutamatergic hyperactivation. Brain Research. 793: 119-26. PMID 9630562 DOI: 10.1016/S0006-8993(98)00167-X  1
1998 Sei Y, Kustova Y, Li Y, Morse HC, Skolnick P, Basile AS. The encephalopathy associated with murine acquired immunodeficiency syndrome. Annals of the New York Academy of Sciences. 840: 822-34. PMID 9629308 DOI: 10.1111/j.1749-6632.1998.tb09620.x  1
1998 Sei Y, Fossom L, Goping G, Skolnick P, Basile AS. Quinolinic acid protects rat cerebellar granule cells from glutamate-induced apoptosis. Neuroscience Letters. 241: 180-4. PMID 9507950 DOI: 10.1016/S0304-3940(97)00980-4  1
1997 Acri JB, Wong G, Lyon T, Witkin JM, Basile AS. Localization and pharmacological characterization of pigeon diazepam-insensitive GABAA receptors. Neuroscience. 77: 371-8. PMID 9472397 DOI: 10.1016/S0306-4522(96)00469-1  1
1997 Drugan RC, Basile AS, Ha JH, Healy D, Ferland RJ. Analysis of the importance of controllable versus uncontrollable stress on subsequent behavioral and physiological functioning. Brain Research. Brain Research Protocols. 2: 69-74. PMID 9438074 DOI: 10.1016/S1385-299X(97)00031-7  1
1997 Ha JH, Knauer S, Moody E, Jones EA, Basile AS. Direct enhancement of GABA-ergic neurotransmission by ammonia. Advances in Experimental Medicine and Biology. 420: 85-94. PMID 9286428  1
1997 Jones EA, Basile AS. The involvement of ammonia with the mechanisms that enhance GABA-ergic neurotransmission in hepatic failure. Advances in Experimental Medicine and Biology. 420: 75-83. PMID 9286427  1
1997 Basile AS, Jones EA. Ammonia and GABA-ergic neurotransmission: interrelated factors in the pathogenesis of hepatic encephalopathy. Hepatology (Baltimore, Md.). 25: 1303-5. PMID 9185743 DOI: 10.1002/hep.510250636  1
1997 Kustova Y, Espey MG, Sei Y, Basile AS. Regional decreases [corrected] in AMPA receptor density in mice infected with the LP-BM5 murine leukemia virus. Neuroreport. 8: 1243-7. PMID 9175122  1
1997 Kupczyk-Subotkowska L, Siahaan TJ, Basile AS, Friedman HS, Higgins PE, Song D, Gallo JM. Modulation of melphalan resistance in glioma cells with a peripheral benzodiazepine receptor ligand-melphalan conjugate. Journal of Medicinal Chemistry. 40: 1726-30. PMID 9171882 DOI: 10.1021/jm960592p  1
1997 Sei Y, Nishida K, Kustova Y, Markey SP, Morse HC, Basile AS. Pentoxifylline decreases brain levels of platelet activating factor in murine AIDS. European Journal of Pharmacology. 325: 81-4. PMID 9151942 DOI: 10.1016/S0014-2999(97)89963-3  1
1997 Li Y, Kustova Y, Sei Y, Basile AS. Regional changes in constitutive, but not inducible NOS expression in the brains of mice infected with the LP-BM5 leukemia virus. Brain Research. 752: 107-16. PMID 9106446 DOI: 10.1016/S0006-8993(96)01459-X  1
1996 Kustova Y, Sei Y, Goping G, Basile AS. Gliosis in the LP-BM5 murine leukemia virus-infected mouse: an animal model of retrovirus-induced dementia. Brain Research. 742: 271-82. PMID 9117405 DOI: 10.1016/S0006-8993(96)01014-1  1
1996 Basile AS, Huang JM, Xie C, Webster D, Berlin C, Skolnick P. N-methyl-D-aspartate antagonists limit aminoglycoside antibiotic-induced hearing loss. Nature Medicine. 2: 1338-43. PMID 8946832 DOI: 10.1038/nm1296-1338  1
1996 Anzini M, Cappelli A, Vomero S, Giorgi G, Langer T, Bruni G, Romeo MR, Basile AS. Molecular basis of peripheral vs central benzodiazepine receptor selectivity in a new class of peripheral benzodiazepine receptor ligands related to alpidem. Journal of Medicinal Chemistry. 39: 4275-84. PMID 8863805 DOI: 10.1021/jm960325j  1
1996 Ha JH, Basile AS. Modulation of ligand binding to components of the GABAA receptor complex by ammonia: implications for the pathogenesis of hyperammonemic syndromes. Brain Research. 720: 35-44. PMID 8782894 DOI: 10.1016/0006-8993(96)00104-7  1
1996 Saito K, Suyama K, Nishida K, Sei Y, Basile AS. Early increases in TNF-alpha, IL-6 and IL-1 beta levels following transient cerebral ischemia in gerbil brain. Neuroscience Letters. 206: 149-52. PMID 8710173 DOI: 10.1016/S0304-3940(96)12460-5  1
1996 Sei Y, Whitesell L, Kustova Y, Paul IA, Morse HC, Skolnick P, Basile AS. Altered brain fyn kinase in a murine acquired immunodeficiency syndrome. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 10: 339-44. PMID 8641568  1
1996 Nishida K, Markey SP, Kustova Y, Morse HC, Skolnick P, Basile AS, Sei Y. Increased brain levels of platelet-activating factor in a murine acquired immune deficiency syndrome are NMDA receptor-mediated. Journal of Neurochemistry. 66: 433-5. PMID 8522986  1
1996 Acri JB, Shah JH, Newman AH, Belov YP, Basile AS, Sharpe LG, Witkin JM. Behavioral effects and dopamine antagonist properties of N-alkylaminobenzazepines Drug Development Research. 37: 39-47. DOI: 10.1002/(SICI)1098-2299(199601)37:1<39::AID-DDR2>3.0.CO;2-N  1
1996 Acril JB, Wong G, Lvon ZT, Witkinl JM, Basile AS. Localization and pharmacology of pigeon diazepam-insensitive γ-aminobutyric acid a receptors Faseb Journal. 10: A155.  1
1995 Fossom LH, Basile AS, Skolnick P. Sustained exposure to 1-aminocyclopropanecarboxylic acid, a glycine partial agonist, alters N-methyl-D-aspartate receptor function and subunit composition. Molecular Pharmacology. 48: 981-7. PMID 8848014  1
1995 Basile AS, Saito K, al-Mardini H, Record CO, Hughes RD, Harrison P, Williams R, Li Y, Heyes MP. The relationship between plasma and brain quinolinic acid levels and the severity of hepatic encephalopathy. Gastroenterology. 108: 818-23. PMID 7875484 DOI: 10.1016/0016-5085(95)90456-5  1
1995 Sei Y, Takemura M, Gusovsky F, Skolnick P, Basile A. Distinct mechanisms for Ca2+ entry induced by OKT3 and Ca2+ depletion in Jurkat T cells. Experimental Cell Research. 216: 222-31. PMID 7813624 DOI: 10.1006/excr.1995.1028  1
1995 Basile AS, Saito K, Li Y, Heyes MP. The relationship between plasma and brain quinolinic acid levels and the severity of hepatic encephalopathy in animal models of fulminant hepatic failure. Journal of Neurochemistry. 64: 2607-14. PMID 7760040  1
1995 Yurdaydin C, Li Y, Ha JH, Jones EA, Rothman R, Basile AS. Brain and plasma levels of opioid peptides are altered in rats with thioacetamide-induced fulminant hepatic failure: implications for the treatment of hepatic encephalopathy with opioid antagonists. The Journal of Pharmacology and Experimental Therapeutics. 273: 185-92. PMID 7714765  1
1995 Yurdaydin C, Walsh TJ, Engler HD, Ha JH, Li Y, Jones EA, Basile AS. Gut bacteria provide precursors of benzodiazepine receptor ligands in a rat model of hepatic encephalopathy. Brain Research. 679: 42-8. PMID 7648264 DOI: 10.1016/0006-8993(95)00241-H  1
1995 Ha JH, Sei Y, Basile AS. Striatal met-enkephalin and substance P levels are decreased in mice infected with the LP-BM5 murine leukemia virus. Journal of Neurochemistry. 64: 1896-8. PMID 7534338  1
1994 Basile AS, Harrison PM, Hughes RD, Gu ZQ, Pannell L, McKinney A, Jones EA, Williams R. Relationship between plasma benzodiazepine receptor ligand concentrations and severity of hepatic encephalopathy. Hepatology (Baltimore, Md.). 19: 112-21. PMID 8276347 DOI: 10.1016/0270-9139(94)90061-2  1
1994 Basile AS, DeCosta B, Paul IA. Multiple [3H]DTG binding sites in guinea pig cerebellum: evidence for the presence of non-specific binding. European Journal of Pharmacology. 252: 139-46. PMID 8157054 DOI: 10.1016/0014-2999(94)90589-4  1
1994 Harris BD, Moody EJ, Basile AS, Skolnick P. Volatile anesthetics bidirectionally and stereospecifically modulate ligand binding to GABA receptors. European Journal of Pharmacology. 267: 269-74. PMID 8088365 DOI: 10.1016/0922-4106(94)90150-3  1
1994 Sei Y, Von Lubitz KJ, Basile AS, Borner MM, Lin RC, Skolnick P, Fossom LH. Internucleosomal DNA fragmentation in gerbil hippocampus following forebrain ischemia. Neuroscience Letters. 171: 179-82. PMID 8084486 DOI: 10.1016/0304-3940(94)90634-3  1
1994 Basile AS, Jones EA. The involvement of benzodiazepine receptor ligands in hepatic encephalopathy. Hepatology (Baltimore, Md.). 20: 541-3. PMID 8045517  1
1994 Drugan RC, Basile AS, Ha JH, Ferland RJ. The protective effects of stress control may be mediated by increased brain levels of benzodiazepine receptor agonists. Brain Research. 661: 127-36. PMID 7834364 DOI: 10.1016/0006-8993(94)91189-4  1
1994 Jones EA, Yurdaydin C, Basile AS. The GABA hypothesis--state of the art. Advances in Experimental Medicine and Biology. 368: 89-101. PMID 7741019  1
1993 Mullen KD, Basile AS. Benzodiazepine-receptor antagonists and hepatic encephalopathy: where do we stand? Gastroenterology. 105: 937-40. PMID 8395446  1
1993 Fryer RI, Zhang P, Rios R, Gu ZQ, Basile AS, Skolnick P. Structure-activity relationship studies at the benzodiazepine receptor (BZR): a comparison of the substitutent effects of pyrazoloquinolinone analogs. Journal of Medicinal Chemistry. 36: 1669-73. PMID 8388472  1
1993 Yurdaydin C, Gu ZQ, Nowak G, Fromm C, Holt AG, Basile AS. Benzodiazepine receptor ligands are elevated in an animal model of hepatic encephalopathy: relationship between brain concentration and severity of encephalopathy. The Journal of Pharmacology and Experimental Therapeutics. 265: 565-71. PMID 8388453  1
1993 Paul IA, Basile AS, Rojas E, Youdim MB, De Costa B, Skolnick P, Pollard HB, Kuijpers GA. Sigma receptors modulate nicotinic receptor function in adrenal chromaffin cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 7: 1171-8. PMID 8375616  1
1993 Jones EA, Basile AS, Yurdaydin C, Skolnich P. Do benzodiazepine ligands contribute to hepatic encephalopathy? Advances in Experimental Medicine and Biology. 341: 57-69. PMID 8116487  1
1993 Jones EA, Yurdaydin C, Basile AS. The role of endogenous benzodiazepines in hepatic encephalopathy: animal studies. Alcohol and Alcoholism (Oxford, Oxfordshire). Supplement. 2: 175-80. PMID 7748296  1
1992 Basile AS, Paul IA, de Costa B. Differential effects of cytochrome P-450 induction on ligand binding to sigma receptors. European Journal of Pharmacology. 227: 95-8. PMID 1426026 DOI: 10.1016/0922-4106(92)90148-O  1
1992 Basile AS, Paul IA, Mirchevich A, Kuijpers G, De Costa B. Modulation of (+)-[3H]pentazocine binding to guinea pig cerebellum by divalent cations. Molecular Pharmacology. 42: 882-9. PMID 1279378  1
1991 Moreno-Sánchez R, Hogue BA, Bravo C, Newman AH, Basile AS, Chiang PK. Inhibition of substrate oxidation in mitochondria by the peripheral-type benzodiazepine receptor ligand AHN 086. Biochemical Pharmacology. 41: 1479-84. PMID 1850277 DOI: 10.1016/0006-2952(91)90564-L  1
1991 Basile AS. The contribution of endogenous benzodiazepine receptor ligands to the pathogenesis of hepatic encephalopathy. Synapse (New York, N.Y.). 7: 141-50. PMID 1849322 DOI: 10.1002/syn.890070208  1
1991 Basile AS, Jones EA, Skolnick P. The pathogenesis and treatment of hepatic encephalopathy: evidence for the involvement of benzodiazepine receptor ligands. Pharmacological Reviews. 43: 27-71. PMID 1674609  1
1991 Basile AS, Hughes RD, Harrison PM, Murata Y, Pannell L, Jones EA, Williams R, Skolnick P. Elevated brain concentrations of 1,4-benzodiazepines in fulminant hepatic failure. The New England Journal of Medicine. 325: 473-8. PMID 1649403 DOI: 10.1056/NEJM199108153250705  1
1990 Gammal SH, Basile AS, Geller D, Skolnick P, Jones EA. Reversal of the behavioral and electrophysiological abnormalities of an animal model of hepatic encephalopathy by benzodiazepine receptor ligands. Hepatology (Baltimore, Md.). 11: 371-8. PMID 2155865  1
1990 Basile AS, Ostrowski NL, Gammal SH, Jones EA, Skolnick P. The GABAA receptor complex in hepatic encephalopathy. Autoradiographic evidence for the presence of elevated levels of a benzodiazepine receptor ligand. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 3: 61-71. PMID 2154999  1
1990 Jones EA, Basile AS, Mullen KD, Gammal SH. Flumazenil: potential implications for hepatic encephalopathy. Pharmacology & Therapeutics. 45: 331-43. PMID 2105510 DOI: 10.1016/0163-7258(90)90070-I  1
1990 Basile AS, Pannell L, Jaouni T, Gammal SH, Fales HM, Jones EA, Skolnick P. Brain concentrations of benzodiazepines are elevated in an animal model of hepatic encephalopathy. Proceedings of the National Academy of Sciences of the United States of America. 87: 5263-7. PMID 1973539 DOI: 10.1073/pnas.87.14.5263  1
1990 Jones EA, Basile AS, Skolnick P. Hepatic encephalopathy, GABA-ergic neurotransmission and benzodiazepine receptor ligands. Advances in Experimental Medicine and Biology. 272: 121-34. PMID 1966504 DOI: 10.1016/B978-008045046-9.00585-4  1
1990 Basile AS, Ostrowski NL, Gammal SH, Jones EA, Skolnick P. The involvement of the benzodiazepine receptor in hepatic encephalopathy: evidence for the presence of a benzodiazepine receptor ligand. Advances in Biochemical Psychopharmacology. 46: 189-200. PMID 1963266  1
1989 Basile AS, Gammal SH, Jones EA, Skolnick P. GABAA receptor complex in an experimental model of hepatic encephalopathy: evidence for elevated levels of an endogenous benzodiazepine receptor ligand. Journal of Neurochemistry. 53: 1057-63. PMID 2549194  1
1989 Jones EA, Skolnick P, Gammal SH, Basile AS, Mullen KD. NIH conference. The gamma-aminobutyric acid A (GABAA) receptor complex and hepatic encephalopathy. Some recent advances. Annals of Internal Medicine. 110: 532-46. PMID 2538099  1
1989 Basile AS, Bolger GT, Lueddens HW, Skolnick P. Electrophysiological actions of Ro5-4864 on cerebellar Purkinje neurons: evidence for "peripheral" benzodiazepine receptor-mediated depression. The Journal of Pharmacology and Experimental Therapeutics. 248: 463-9. PMID 2536432  1
1989 Bolger GT, Newman AH, Rice KC, Lueddens HW, Basile AS, Skolnick P. Characterization of the effects of AHN 086, an irreversible ligand of "peripheral" benzodiazepine receptors, on contraction in guinea-pig atrial and ileal longitudinal smooth muscle. Canadian Journal of Physiology and Pharmacology. 67: 126-34. PMID 2469529  1
1988 Basile AS, Gammal SH. Evidence for the involvement of the benzodiazepine receptor complex in hepatic encephalopathy. Implications for treatment with benzodiazepine receptor antagonists. Clinical Neuropharmacology. 11: 401-22. PMID 2905934  1
1988 Basile AS, Gammal SH, Mullen KD, Jones EA, Skolnick P. Differential responsiveness of cerebellar Purkinje neurons to GABA and benzodiazepine receptor ligands in an animal model of hepatic encephalopathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 2414-21. PMID 2854841  1
1988 Drugan RC, Basile AS, Crawley JN, Paul SM, Skolnick P. Characterization of stress-induced alterations in [3H] Ro5-4864 binding to peripheral benzodiazepine receptors in rat heart and kidney. Pharmacology, Biochemistry, and Behavior. 30: 1015-20. PMID 2852369 DOI: 10.1016/0091-3057(88)90134-7  1
1988 Basile AS, Lueddens HW, Skolnick P. Regulation of renal peripheral benzodiazepine receptors by anion transport inhibitors. Life Sciences. 42: 715-26. PMID 2828800 DOI: 10.1016/0024-3205(88)90464-X  1
1988 Basile AS, Skolnick P. Tissue specific regulation of "peripheral-type" benzodiazepine receptor density after chemical sympathectomy. Life Sciences. 42: 273-83. PMID 2826958 DOI: 10.1016/0024-3205(88)90636-4  1
1988 Bolger GT, Lesieur P, Basile AS, Skolnick P. Modulation of neurotransmitter metabolism by dihydropyridine calcium channel ligands in mouse brain. Brain Research. 438: 101-7. PMID 2449929 DOI: 10.1016/0006-8993(88)91328-5  1
1988 Basile AS, Jones EA. Hepatic encephalopathy and the GABA/benzodiazepine receptor-chloride ionophore complex: An update Journal of Gastroenterology and Hepatology. 3: 387-398.  1
1987 Bolger GT, Basile AS, Janowsky AJ, Paul SM, Skolnick P. Regulation of dihydropyridine calcium antagonist binding sites in the rat hippocampus following neurochemical lesions. Journal of Neuroscience Research. 17: 285-90. PMID 3037095 DOI: 10.1002/jnr.490170313  1
1987 Basile AS, Skolnick P. Preservation of "peripheral" benzodiazepine receptors: differential effects of freezing on [3H]Ro 5-4864 and [3H]PK 11195 binding. Journal of Pharmacological Methods. 17: 149-56. PMID 3035290 DOI: 10.1016/0160-5402(87)90025-8  1
1987 Basile AS, Ostrowski NL, Skolnick P. Aldosterone-reversible decrease in the density of renal peripheral benzodiazepine receptors in the rat after adrenalectomy. The Journal of Pharmacology and Experimental Therapeutics. 240: 1006-13. PMID 3031271  1
1987 Drugan RC, Basile AS, Crawley JN, Paul SM, Skolnick P. "Peripheral" benzodiazepine binding sites in the Maudsley reactive rat: selective decrease confined to peripheral tissues. Brain Research Bulletin. 18: 143-5. PMID 3030509 DOI: 10.1016/0361-9230(87)90044-X  1
1987 Trudell ML, Basile AS, Shannon HE, Skolnick P, Cook JM. Synthesis of 7,12-dihydropyrido[3,4-b:5,4-b']diindoles. A novel class of rigid, planar benzodiazepine receptor ligands. Journal of Medicinal Chemistry. 30: 456-8. PMID 3029372  1
1987 Basile AS, Weissman BA, Skolnick P. Maximal electroshock increases the density of [3H]Ro 5-4864 binding to mouse cerebral cortex. Brain Research Bulletin. 19: 1-7. PMID 2820550 DOI: 10.1016/0361-9230(87)90158-4  1
1986 Basile AS, Klein DC, Skolnick P. Characterization of benzodiazepine receptors in the bovine pineal gland: evidence for the presence of an atypical binding site. Brain Research. 387: 127-35. PMID 3024779 DOI: 10.1016/0169-328X(86)90004-5  1
1986 Drugan RC, Basile AS, Crawley JN, Paul SM, Skolnick P. Inescapable shock reduces [3H]Ro 5-4864 binding to "peripheral-type" benzodiazepine receptors in the rat. Pharmacology, Biochemistry, and Behavior. 24: 1673-7. PMID 3016760 DOI: 10.1016/0091-3057(86)90504-6  1
1986 Basile AS, Skolnick P. Subcellular localization of "peripheral-type" binding sites for benzodiazepines in rat brain. Journal of Neurochemistry. 46: 305-8. PMID 2999338  1
1985 Bolger GT, Weissman BA, Lueddens H, Basile AS, Mantione CR, Barrett JE, Witkin JM, Paul SM, Skolnick P. Late evolutionary appearance of 'peripheral-type' binding sites for benzodiazepines. Brain Research. 338: 366-70. PMID 2992689 DOI: 10.1016/0006-8993(85)90170-2  1
1985 Basile AS, Paul SM, Skolnick P. Adrenalectomy reduces the density of 'peripheral-type' binding sites for benzodiazepines in the rat kidney. European Journal of Pharmacology. 110: 149-50. PMID 2988979 DOI: 10.1016/0014-2999(85)90044-5  1
1985 Basile AS, Skolnick P. Adrenalectomy (ADX) reduces the density of 'peripheral-type' binding sites for benzodiazepines in kidney Federation Proceedings. 44: No. 4806.  1
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