Michael Sacher - Publications

Affiliations: 
Concordia University (Canada), Montreal, QC, Canada 
Area:
membrane traffic

49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, ... ... Sacher M, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 1-382. PMID 33634751 DOI: 10.1080/15548627.2020.1797280  0.53
2020 Milev MP, Saint-Dic D, Zardoui K, Klopstock T, Law C, Distelmaier F, Sacher M. The phenotype associated with variants in TANGO2 may be explained by a dual role of the protein in ER-to-Golgi transport and at the mitochondria. Journal of Inherited Metabolic Disease. PMID 32909282 DOI: 10.1002/Jimd.12312  0.447
2020 Al-Deri N, Okur V, Ahimaz P, Milev M, Valivullah Z, Hagen J, Sheng Y, Chung W, Sacher M, Ganapathi M. A novel homozygous variant in results in a neurodevelopmental disorder and disrupts TRAPP complex function. Journal of Medical Genetics. PMID 32843486 DOI: 10.1136/Jmedgenet-2020-107016  0.359
2020 Lipatova Z, Van Bergen N, Stanga D, Sacher M, Christodoulou J, Segev N. TRAPPing a neurological disorder: from yeast to humans. Autophagy. 1-2. PMID 32116085 DOI: 10.1080/15548627.2020.1736873  0.456
2019 Van Bergen NJ, Guo Y, Al-Deri N, Lipatova Z, Stanga D, Zhao S, Murtazina R, Gyurkovska V, Pehlivan D, Mitani T, Gezdirici A, Antony J, Collins F, Willis MJH, Coban Akdemir ZH, ... ... Sacher M, et al. Deficiencies in vesicular transport mediated by TRAPPC4 are associated with severe syndromic intellectual disability. Brain : a Journal of Neurology. PMID 31794024 DOI: 10.1093/Brain/Awz374  0.417
2019 Milev MP, Stanga D, Schänzer A, Nascimento A, Saint-Dic D, Ortez C, Benito DN, Barrios DG, Colomer J, Badosa C, Jou C, Gallano P, Gonzalez-Quereda L, Töpf A, Johnson K, ... ... Sacher M, et al. Characterization of three TRAPPC11 variants suggests a critical role for the extreme carboxy terminus of the protein. Scientific Reports. 9: 14036. PMID 31575891 DOI: 10.1038/S41598-019-50415-6  0.422
2019 Stanga D, Zhao Q, Milev MP, Saint-Dic D, Jimenez-Mallebrera C, Sacher M. TRAPPC11 functions in autophagy by recruiting ATG2B-WIPI4/WDR45 to preautophagosomal membranes. Traffic (Copenhagen, Denmark). PMID 30843302 DOI: 10.1111/Tra.12640  0.438
2018 Sacher M, Shahrzad N, Kamel H, Milev MP. TRAPPopathies, an emerging set of disorders linked to variations in the genes encoding transport protein particle (TRAPP)-associated proteins. Traffic (Copenhagen, Denmark). PMID 30152084 DOI: 10.1111/Tra.12615  0.451
2018 Larson AA, Baker PR, Milev MP, Press CA, Sokol RJ, Cox MO, Lekostaj JK, Stence AA, Bossler AD, Mueller JM, Prematilake K, Tadjo TF, Williams CA, Sacher M, Moore SA. TRAPPC11 and GOSR2 mutations associate with hypoglycosylation of α-dystroglycan and muscular dystrophy. Skeletal Muscle. 8: 17. PMID 29855340 DOI: 10.1186/S13395-018-0163-0  0.457
2017 Milev MP, Grout ME, Saint-Dic D, Cheng YH, Glass IA, Hale CJ, Hanna DS, Dorschner MO, Prematilake K, Shaag A, Elpeleg O, Sacher M, Doherty D, Edvardson S. Mutations in TRAPPC12 Manifest in Progressive Childhood Encephalopathy and Golgi Dysfunction. American Journal of Human Genetics. 101: 291-299. PMID 28777934 DOI: 10.1016/J.Ajhg.2017.07.006  0.415
2016 Milev MP, Sacher M. TRAMM, a new player in CENP-E biology. Molecular & Cellular Oncology. 3: e1057314. PMID 27308570 DOI: 10.1080/23723556.2015.1057314  0.374
2016 Brunet S, Saint-Dic D, Milev MP, Nilsson T, Sacher M. The TRAPP Subunit Trs130p Interacts with the GAP Gyp6p to Mediate Ypt6p Dynamics at the Late Golgi. Frontiers in Cell and Developmental Biology. 4: 48. PMID 27252941 DOI: 10.3389/Fcell.2016.00048  0.414
2016 DeRossi C, Vacaru A, Rafiq R, Cinaroglu A, Imrie D, Nayar S, Baryshnikova A, Milev MP, Stanga D, Kadakia D, Gao N, Chu J, Freeze HH, Lehrman MA, Sacher M, et al. trappc11 is required for protein glycosylation in zebrafish and humans. Molecular Biology of the Cell. PMID 26912795 DOI: 10.1091/Mbc.E15-08-0557  0.441
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin J, Abeliovich H, Arozena AA, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Sacher M, et al. Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 Autophagy. 12: 443-443. PMID 26902590 DOI: 10.1080/15548627.2016.1147886  0.434
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Sacher M, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.515
2015 Liang WC, Zhu W, Mitsuhashi S, Noguchi S, Sacher M, Ogawa M, Shih HH, Jong YJ, Nishino I. Congenital muscular dystrophy with fatty liver and infantile-onset cataract caused by TRAPPC11 mutations: broadening of the phenotype. Skeletal Muscle. 5: 29. PMID 26322222 DOI: 10.1186/S13395-015-0056-4  0.338
2015 Milev MP, Sacher M. Mitotic transformation of TRAMM/TrappC12. Oncotarget. 6: 17853-4. PMID 26257002 DOI: 10.18632/Oncotarget.4843  0.507
2014 Brunet S, Sacher M. Are all multisubunit tethering complexes bona fide tethers? Traffic (Copenhagen, Denmark). 15: 1282-7. PMID 25048641 DOI: 10.1111/Tra.12200  0.424
2014 Brunet S, Sacher M. In sickness and in health: the role of TRAPP and associated proteins in disease. Traffic (Copenhagen, Denmark). 15: 803-18. PMID 24917561 DOI: 10.1111/Tra.12183  0.434
2013 Brunet S, Shahrzad N, Saint-Dic D, Dutczak H, Sacher M. A trs20 mutation that mimics an SEDT-causing mutation blocks selective and non-selective autophagy: a model for TRAPP III organization. Traffic (Copenhagen, Denmark). 14: 1091-104. PMID 23898804 DOI: 10.1111/Tra.12095  0.4
2013 Bögershausen N, Shahrzad N, Chong JX, von Kleist-Retzow JC, Stanga D, Li Y, Bernier FP, Loucks CM, Wirth R, Puffenberger EG, Hegele RA, Schreml J, Lapointe G, Keupp K, Brett CL, ... ... Sacher M, et al. Recessive TRAPPC11 mutations cause a disease spectrum of limb girdle muscular dystrophy and myopathy with movement disorder and intellectual disability. American Journal of Human Genetics. 93: 181-90. PMID 23830518 DOI: 10.1016/J.Ajhg.2013.05.028  0.427
2012 Brunet S, Noueihed B, Shahrzad N, Saint-Dic D, Hasaj B, Guan TL, Moores A, Barlowe C, Sacher M. The SMS domain of Trs23p is responsible for the in vitro appearance of the TRAPP I complex in Saccharomyces cerevisiae. Cellular Logistics. 2: 28-42. PMID 22645708 DOI: 10.4161/Cl.19414  0.442
2011 Duarte DT, Hul S, Sacher M. A yeast two hybrid screen identifies SPATA4 as a TRAPP interactor. Febs Letters. 585: 2676-81. PMID 21827752 DOI: 10.1016/J.Febslet.2011.07.040  0.481
2011 Scrivens PJ, Noueihed B, Shahrzad N, Hul S, Brunet S, Sacher M. C4orf41 and TTC-15 are mammalian TRAPP components with a role at an early stage in ER-to-Golgi trafficking. Molecular Biology of the Cell. 22: 2083-93. PMID 21525244 DOI: 10.1091/Mbc.E10-11-0873  0.425
2009 Scrivens PJ, Shahrzad N, Moores A, Morin A, Brunet S, Sacher M. TRAPPC2L is a novel, highly conserved TRAPP-interacting protein. Traffic (Copenhagen, Denmark). 10: 724-36. PMID 19416478 DOI: 10.1111/J.1600-0854.2009.00906.X  0.482
2008 Sacher M, Kim YG, Lavie A, Oh BH, Segev N. The TRAPP complex: insights into its architecture and function. Traffic (Copenhagen, Denmark). 9: 2032-42. PMID 18801063 DOI: 10.1111/J.1600-0854.2008.00833.X  0.538
2006 Kim YG, Raunser S, Munger C, Wagner J, Song YL, Cygler M, Walz T, Oh BH, Sacher M. The architecture of the multisubunit TRAPP I complex suggests a model for vesicle tethering. Cell. 127: 817-30. PMID 17110339 DOI: 10.1016/J.Cell.2006.09.029  0.502
2005 Sacher M, Di Bacco A, Lunin VV, Ye Z, Wagner J, Gill G, Cygler M. The crystal structure of CREG, a secreted glycoprotein involved in cellular growth and differentiation. Proceedings of the National Academy of Sciences of the United States of America. 102: 18326-31. PMID 16344469 DOI: 10.1073/Pnas.0505071102  0.337
2005 Kim MS, Yi MJ, Lee KH, Wagner J, Munger C, Kim YG, Whiteway M, Cygler M, Oh BH, Sacher M. Biochemical and crystallographic studies reveal a specific interaction between TRAPP subunits Trs33p and Bet3p. Traffic (Copenhagen, Denmark). 6: 1183-95. PMID 16262728 DOI: 10.1111/J.1600-0854.2005.00352.X  0.519
2005 Kim YG, Sohn EJ, Seo J, Lee KJ, Lee HS, Hwang I, Whiteway M, Sacher M, Oh BH. Crystal structure of bet3 reveals a novel mechanism for Golgi localization of tethering factor TRAPP. Nature Structural & Molecular Biology. 12: 38-45. PMID 15608655 DOI: 10.1038/Nsmb871  0.398
2004 Lunin VV, Munger C, Wagner J, Ye Z, Cygler M, Sacher M. The structure of the MAPK scaffold, MP1, bound to its partner, p14. A complex with a critical role in endosomal map kinase signaling. The Journal of Biological Chemistry. 279: 23422-30. PMID 15016825 DOI: 10.1074/Jbc.M401648200  0.471
2003 Sacher M. Membrane traffic fuses with cartilage development. Febs Letters. 550: 1-4. PMID 12935876 DOI: 10.1016/S0014-5793(03)00854-8  0.428
2001 Kim DW, Massey T, Sacher M, Pypaert M, Ferro-Novick S. Sgf1p, a new component of the Sec34p/Sec35p complex. Traffic (Copenhagen, Denmark). 2: 820-30. PMID 11733049 DOI: 10.1034/J.1600-0854.2001.21111.X  0.705
2001 Sacher M, Barrowman J, Wang W, Horecka J, Zhang Y, Pypaert M, Ferro-Novick S. TRAPP I implicated in the specificity of tethering in ER-to-Golgi transport. Molecular Cell. 7: 433-42. PMID 11239471 DOI: 10.1016/S1097-2765(01)00190-3  0.779
2001 Sacher M, Ferro-Novick S. Purification of TRAPP from Saccharomyces cerevisiae and identification of its mammalian counterpart. Methods in Enzymology. 329: 234-41. PMID 11210539 DOI: 10.1016/S0076-6879(01)29083-1  0.646
2000 Wang W, Sacher M, Ferro-Novick S. TRAPP stimulates guanine nucleotide exchange on Ypt1p. The Journal of Cell Biology. 151: 289-96. PMID 11038176 DOI: 10.1083/Jcb.151.2.289  0.723
2000 Guo W, Sacher M, Barrowman J, Ferro-Novick S, Novick P. Protein complexes in transport vesicle targeting. Trends in Cell Biology. 10: 251-5. PMID 10802541 DOI: 10.1016/S0962-8924(00)01754-2  0.774
2000 Sacher M, Barrowman J, Schieltz D, Yates JR, Ferro-Novick S. Identification and characterization of five new subunits of TRAPP. European Journal of Cell Biology. 79: 71-80. PMID 10727015 DOI: 10.1078/S0171-9335(04)70009-6  0.759
2000 Barrowman J, Sacher M, Ferro-Novick S. TRAPP stably associates with the Golgi and is required for vesicle docking. The Embo Journal. 19: 862-9. PMID 10698928 DOI: 10.1093/Emboj/19.5.862  0.77
1999 Kim DW, Sacher M, Scarpa A, Quinn AM, Ferro-Novick S. High-copy suppressor analysis reveals a physical interaction between Sec34p and Sec35p, a protein implicated in vesicle docking. Molecular Biology of the Cell. 10: 3317-29. PMID 10512869 DOI: 10.1091/Mbc.10.10.3317  0.698
1998 Sacher M, Jiang Y, Barrowman J, Scarpa A, Burston J, Zhang L, Schieltz D, Yates JR, Abeliovich H, Ferro-Novick S. TRAPP, a highly conserved novel complex on the cis-Golgi that mediates vesicle docking and fusion. The Embo Journal. 17: 2494-503. PMID 9564032 DOI: 10.1093/Emboj/17.9.2494  0.781
1997 Stone S, Sacher M, Mao Y, Carr C, Lyons P, Quinn AM, Ferro-Novick S. Bet1p activates the v-SNARE Bos1p. Molecular Biology of the Cell. 8: 1175-81. PMID 9243499 DOI: 10.1091/Mbc.8.7.1175  0.694
1997 Sacher M, Stone S, Ferro-Novick S. The synaptobrevin-related domains of Bos1p and Sec22p bind to the syntaxin-like region of Sed5p. The Journal of Biological Chemistry. 272: 17134-8. PMID 9202032 DOI: 10.1074/Jbc.272.27.17134  0.678
1997 Athlan ES, Sacher MG, Mushynski WE. Associations between intermediate filament proteins expressed in cultured dorsal root ganglion neurons. Journal of Neuroscience Research. 47: 300-10. PMID 9039652 DOI: 10.1002/(Sici)1097-4547(19970201)47:3<300::Aid-Jnr8>3.0.Co;2-M  0.591
1996 Stone S, Sacher M, Jiang Y, Mao Y, Lyons P, Feliciano E, Ferro-Novick S. A molecular dissection of vesicle targeting and fusion Biochemical Society Transactions. 24: 585S. DOI: 10.1042/Bst024585Sa  0.61
1995 Jiang Y, Sacher M, Singer-Krüger B, Lian JP, Stone S, Ferro-Novick S. Factors mediating the late stages of ER-to-Golgi transport in yeast. Cold Spring Harbor Symposia On Quantitative Biology. 60: 119-26. PMID 8824384 DOI: 10.1101/Sqb.1995.060.01.015  0.631
1994 Sacher MG, Athlan ES, Mushynski WE. Increased phosphorylation of the amino-terminal domain of the low molecular weight neurofilament subunit in okadaic acid-treated neurons. The Journal of Biological Chemistry. 269: 18480-4. PMID 8034596  0.613
1992 Sacher MG, Athlan ES, Mushynski WE. Okadaic acid induces the rapid and reversible disruption of the neurofilament network in rat dorsal root ganglion neurons. Biochemical and Biophysical Research Communications. 186: 524-30. PMID 1321614 DOI: 10.1016/S0006-291X(05)80839-3  0.568
1989 Georges E, Lindenbaum MH, Sacher MG, Trifaró JM, Mushynski WE. Neurofilament phosphorylation in cultured bovine adrenal chromaffin cells is stimulated by phorbol ester. Journal of Neurochemistry. 52: 1156-61. PMID 2926395 DOI: 10.1111/J.1471-4159.1989.Tb01861.X  0.584
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