| Year |
Citation |
Score |
| 2024 |
Joseph TT, Bu W, Haji-Ghassemi O, Chen YS, Woll K, Allen PD, Brannigan G, van Petegem F, Eckenhoff RG. Propofol directly binds and inhibits skeletal muscle ryanodine receptor 1 (RyR1). Biorxiv : the Preprint Server For Biology. PMID 38260485 DOI: 10.1101/2024.01.10.575040 |
0.715 |
|
| 2021 |
Joseph TT, Bu W, Lin W, Zoubak L, Yeliseev A, Liu R, Eckenhoff RG, Brannigan G. Ketamine Metabolite (2,6)-Hydroxynorketamine Interacts with μ and κ Opioid Receptors. Acs Chemical Neuroscience. PMID 33905229 DOI: 10.1021/acschemneuro.0c00741 |
0.695 |
|
| 2020 |
Wague A, Joseph TT, Woll KA, Bu W, Vaidya KA, Bhanu NV, Garcia BA, Nimigean CM, Eckenhoff RG, Riegelhaupt PM. Mechanistic insights into volatile anesthetic modulation of K2P channels. Elife. 9. PMID 33345771 DOI: 10.7554/eLife.59839 |
0.605 |
|
| 2020 |
Koutsogiannaki S, Bu W, Hou L, Shibamura-Fujiogi M, Ishida H, Ohto U, Eckenhoff RG, Yuki K. The effect of anesthetics on toll like receptor 9. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 34: 14645-14654. PMID 32901993 DOI: 10.1096/Fj.202000791Rr |
0.342 |
|
| 2020 |
Yuki K, Bu W, Eckenhoff RG, Yokomizo T, Okuno T. The role of propofol hydroxyl group in 5-lipoxygenase recognition. Biochemical and Biophysical Research Communications. PMID 32171526 DOI: 10.1016/J.Bbrc.2020.03.037 |
0.387 |
|
| 2020 |
Murlidaran S, Bu W, Eckenhoff RG, Brannigan GH, Joseph TT. Relative Affinities of General Anesthetics for Experimentally Identified Binding Sites in Ryanodine Receptors (RyR1) Biophysical Journal. 118: 115a. DOI: 10.1016/J.Bpj.2019.11.771 |
0.788 |
|
| 2019 |
Okuno T, Koutsogiannaki S, Hou L, Bu W, Ohto U, Eckenhoff RG, Yokomizo T, Yuki K. Volatile anesthetics isoflurane and sevoflurane directly target and attenuate Toll-like receptor 4 system. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201901570R. PMID 31675483 DOI: 10.1096/Fj.201901570R |
0.321 |
|
| 2019 |
McKinstry-Wu A, Woll KA, Joseph T, Bu W, White ER, Bhanu NV, Garcia BA, Brannigan G, Dailey WP, Eckenhoff RG. Azi-medetomidine: Synthesis and Characterization of a Novel α2 Adrenergic Photoaffinity Ligand. Acs Chemical Neuroscience. PMID 31638765 DOI: 10.1021/Acschemneuro.9B00484 |
0.715 |
|
| 2019 |
Hemmings HC, Riegelhaupt PM, Kelz MB, Solt K, Eckenhoff RG, Orser BA, Goldstein PA. Towards a Comprehensive Understanding of Anesthetic Mechanisms of Action: A Decade of Discovery. Trends in Pharmacological Sciences. PMID 31147199 DOI: 10.1016/J.Tips.2019.05.001 |
0.37 |
|
| 2018 |
Wang Y, Yang E, Wells MM, Bondarenko V, Woll K, Carnevale V, Granata D, Klein ML, Eckenhoff RG, Dailey WP, Covarrubias M, Tang P, Xu Y. Propofol inhibits the voltage-gated sodium channel NaChBac at multiple sites. The Journal of General Physiology. PMID 30018039 DOI: 10.1085/Jgp.201811993 |
0.411 |
|
| 2018 |
Yang E, Granata D, Eckenhoff RG, Carnevale V, Covarrubias M. Propofol inhibits prokaryotic voltage-gated Na channels by promoting activation-coupled inactivation. The Journal of General Physiology. PMID 30018038 DOI: 10.1085/Jgp.201711924 |
0.334 |
|
| 2018 |
Woll KA, Guzik-Lendrum S, Bensel BM, Bhanu NV, Dailey WP, Garcia BA, Gilbert SP, Eckenhoff RG. An allosteric propofol-binding site in kinesin disrupts kinesin-mediated processive movement on microtubules. The Journal of Biological Chemistry. PMID 29844014 DOI: 10.1074/Jbc.Ra118.002182 |
0.36 |
|
| 2018 |
Woll KA, Dailey WP, Eckenhoff RG. Identification of General Anesthetic Target Protein-Binding Sites by Photoaffinity Labeling and Mass Spectrometry. Methods in Enzymology. 602: 231-246. PMID 29588031 DOI: 10.1016/Bs.Mie.2018.01.009 |
0.373 |
|
| 2018 |
Woll KA, Zhou X, Bhanu NV, Garcia BA, Covarrubias M, Miller KW, Eckenhoff RG. Identification of binding sites contributing to volatile anesthetic effects on GABA type A receptors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201701347R. PMID 29505303 DOI: 10.1096/Fj.201701347R |
0.401 |
|
| 2018 |
Riegelhaupt PM, Woll KA, Joseph TT, Vaidya KA, Nimigean CM, Eckenhoff RG. Identification of a Modulatory Site of Action for the Volatile Anesthetic Isoflurane in TREK1 Tandem Pore Potassium Channels Biophysical Journal. 114: 487a-488a. DOI: 10.1016/J.Bpj.2017.11.2675 |
0.605 |
|
| 2018 |
Joseph TT, Eckenhoff RG, Brannigan G. The pH Dependence of Ketamine Binding to G-Protein Coupled Receptors Biophysical Journal. 114: 226a. DOI: 10.1016/J.Bpj.2017.11.1260 |
0.715 |
|
| 2017 |
Woll KA, Skinner KA, Gianti E, Bhanu NV, Garcia BA, Carnevale V, Eckenhoff RG, Gaudet R. Sites Contributing to TRPA1 Activation by the Anesthetic Propofol Identified by Photoaffinity Labeling. Biophysical Journal. PMID 28935134 DOI: 10.1016/J.Bpj.2017.08.040 |
0.439 |
|
| 2017 |
Bensel BM, Guzik-Lendrum S, Masucci EM, Woll KA, Eckenhoff RG, Gilbert SP. Common general anesthetic propofol impairs kinesin processivity. Proceedings of the National Academy of Sciences of the United States of America. PMID 28484025 DOI: 10.1073/Pnas.1701482114 |
0.41 |
|
| 2017 |
Woll KA, Peng W, Liang Q, Zhi L, Jacobs JA, Maciunas L, Bhanu N, Garcia BA, Covarrubias M, Loll PJ, Dailey WP, Eckenhoff RG. Photoaffinity ligand for the inhalational anesthetic sevoflurane allows mechanistic insight into potassium channel modulation. Acs Chemical Biology. PMID 28333442 DOI: 10.1021/Acschembio.7B00222 |
0.439 |
|
| 2017 |
Bu W, Liang Q, Zhi L, Maciunas L, Loll PJ, Eckenhoff RG, Covarrubias M. Sites and Functional Consequence of Alkylphenol Anesthetic Binding to Kv1.2 Channels. Molecular Neurobiology. PMID 28204960 DOI: 10.1007/S12035-017-0437-2 |
0.406 |
|
| 2017 |
Okuno T, Koutsogiannaki S, Ohba M, Chamberlain M, Bu W, Lin FY, Eckenhoff RG, Yokomizo T, Yuki K. Intravenous anesthetic propofol binds to 5-lipoxygenase and attenuates leukotriene B4 production. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28069825 DOI: 10.1096/Fj.201601095R |
0.369 |
|
| 2017 |
Wang Y, Wells MM, Dailey W, Eckenhoff R, Tang P, Xu Y. Multiple Mechanisms of Propofol Inhibition of the Voltage-Gated Sodium Channel Nachbac: A 19 F NMR Investigation Biophysical Journal. 112: 18a. DOI: 10.1016/J.Bpj.2016.11.133 |
0.407 |
|
| 2016 |
Kinde MN, Bondarenko V, Granata D, Bu W, Grasty KC, Loll PJ, Carnevale V, Klein ML, Eckenhoff RG, Tang P, Xu Y. Fluorine-19 NMR and computational quantification of isoflurane binding to the voltage-gated sodium channel NaChBac. Proceedings of the National Academy of Sciences of the United States of America. PMID 27856739 DOI: 10.1073/Pnas.1609939113 |
0.343 |
|
| 2016 |
Woll KA, Dailey WP, Brannigan G, Eckenhoff RG. Shedding Light on Anesthetic Mechanisms: Application of Photoaffinity Ligands. Anesthesia and Analgesia. PMID 27464974 DOI: 10.1213/Ane.0000000000001365 |
0.591 |
|
| 2016 |
Woll KA, Murlidaran S, Pinch BJ, Hénin J, Wang X, Salari R, Covarrubias M, Dailey WP, Brannigan G, Garcia BA, Eckenhoff RG. A Novel Bifunctional Alkylphenol Anesthetic Allows Characterization of GABAA Receptor Subunit Binding Selectivity in Synaptosomes. The Journal of Biological Chemistry. PMID 27462076 DOI: 10.1074/Jbc.M116.736975 |
0.787 |
|
| 2016 |
Kinde MN, Bu W, Chen Q, Xu Y, Eckenhoff RG, Tang P. Common Anesthetic-binding Site for Inhibition of Pentameric Ligand-gated Ion Channels. Anesthesiology. PMID 26756520 DOI: 10.1097/Aln.0000000000001005 |
0.417 |
|
| 2015 |
Weiser BP, Hall MA, Weinbren NL, Woll KA, Dailey WP, Eckenhoff MF, Eckenhoff RG. Macroscopic and macromolecular specificity of alkylphenol anesthetics for neuronal substrates. Scientific Reports. 5: 9695. PMID 25853337 DOI: 10.1038/Srep09695 |
0.379 |
|
| 2015 |
Ho J, Perez-Aguilar JM, Gao L, Saven JG, Matsunami H, Eckenhoff RG. Molecular recognition of ketamine by a subset of olfactory G protein-coupled receptors. Science Signaling. 8: ra33. PMID 25829447 DOI: 10.1126/Scisignal.2005912 |
0.391 |
|
| 2015 |
Woll KA, Weiser BP, Liang Q, Meng T, McKinstry-Wu A, Pinch B, Dailey WP, Gao WD, Covarrubias M, Eckenhoff RG. Role for the Propofol Hydroxyl in Anesthetic Protein Target Molecular Recognition. Acs Chemical Neuroscience. 6: 927-35. PMID 25799399 DOI: 10.1021/Acschemneuro.5B00078 |
0.401 |
|
| 2015 |
Weiser BP, Eckenhoff RG. Propofol inhibits SIRT2 deacetylase through a conformation-specific, allosteric site. The Journal of Biological Chemistry. 290: 8559-68. PMID 25666612 DOI: 10.1074/Jbc.M114.620732 |
0.412 |
|
| 2015 |
Kinde MN, Bu W, Seyoum E, Chen Q, Wells MM, Mowrey DD, Eckenhoff RG, Xu Y, Tang P. A Shared Binding Site for Propofol and Thiopental in ELIC Biophysical Journal. 108: 55a. DOI: 10.1016/J.Bpj.2014.11.332 |
0.443 |
|
| 2014 |
Weiser BP, Bu W, Wong D, Eckenhoff RG. Sites and functional consequence of VDAC-alkylphenol anesthetic interactions. Febs Letters. 588: 4398-403. PMID 25448677 DOI: 10.1016/J.Febslet.2014.10.009 |
0.434 |
|
| 2014 |
Jayakar SS, Zhou X, Chiara DC, Dostalova Z, Savechenkov PY, Bruzik KS, Dailey WP, Miller KW, Eckenhoff RG, Cohen JB. Multiple propofol-binding sites in a γ-aminobutyric acid type A receptor (GABAAR) identified using a photoreactive propofol analog. The Journal of Biological Chemistry. 289: 27456-68. PMID 25086038 DOI: 10.1074/Jbc.M114.581728 |
0.36 |
|
| 2014 |
Weiser BP, Salari R, Eckenhoff RG, Brannigan G. Computational investigation of cholesterol binding sites on mitochondrial VDAC. The Journal of Physical Chemistry. B. 118: 9852-60. PMID 25080204 DOI: 10.1021/Jp504516A |
0.638 |
|
| 2014 |
Barber AF, Carnevale V, Klein ML, Eckenhoff RG, Covarrubias M. Modulation of a voltage-gated Na+ channel by sevoflurane involves multiple sites and distinct mechanisms. Proceedings of the National Academy of Sciences of the United States of America. 111: 6726-31. PMID 24753583 DOI: 10.1073/Pnas.1405768111 |
0.39 |
|
| 2014 |
Weiser BP, Woll KA, Dailey WP, Eckenhoff RG. Mechanisms revealed through general anesthetic photolabeling. Current Anesthesiology Reports. 4: 57-66. PMID 24563623 DOI: 10.1007/S40140-013-0040-7 |
0.454 |
|
| 2014 |
Chiara DC, Gill JF, Chen Q, Tillman T, Dailey WP, Eckenhoff RG, Xu Y, Tang P, Cohen JB. Photoaffinity labeling the propofol binding site in GLIC. Biochemistry. 53: 135-42. PMID 24341978 DOI: 10.1021/Bi401492K |
0.417 |
|
| 2014 |
Weiser BP, Salari R, Eckenhoff RG, Brannigan G. Computational investigation of cholesterol binding sites on mitochondrial VDAC Journal of Physical Chemistry B. 118: 9852-9860. DOI: 10.1021/jp504516a |
0.568 |
|
| 2014 |
Woll KA, Pinch BP, Dailey WP, Eckenhoff RG. ‘Clickable’-Photoactive Propofol Analogue for the Identification of Anesthetic Targets Biophysical Journal. 106: 478a. DOI: 10.1016/J.Bpj.2013.11.2701 |
0.375 |
|
| 2013 |
Yuki K, Bu W, Xi J, Shimaoka M, Eckenhoff R. Propofol shares the binding site with isoflurane and sevoflurane on leukocyte function-associated antigen-1. Anesthesia and Analgesia. 117: 803-11. PMID 23960033 DOI: 10.1213/Ane.0B013E3182A00Ae0 |
0.372 |
|
| 2013 |
Yuki K, Bu W, Shimaoka M, Eckenhoff R. Volatile Anesthetics, Not Intravenous Anesthetic Propofol Bind to and Attenuate the Activation of Platelet Receptor Integrin αIIbβ3 Plos One. 8. PMID 23573252 DOI: 10.1371/Journal.Pone.0060415 |
0.43 |
|
| 2013 |
Emerson DJ, Weiser BP, Psonis J, Liao Z, Taratula O, Fiamengo A, Wang X, Sugasawa K, Smith AB, Eckenhoff RG, Dmochowski IJ. Direct modulation of microtubule stability contributes to anthracene general anesthesia. Journal of the American Chemical Society. 135: 5389-98. PMID 23484901 DOI: 10.1021/Ja311171U |
0.351 |
|
| 2013 |
Jayakar SS, Dailey WP, Eckenhoff RG, Cohen JB. Identification of propofol binding sites in a nicotinic acetylcholine receptor with a photoreactive propofol analog. The Journal of Biological Chemistry. 288: 6178-89. PMID 23300078 DOI: 10.1074/Jbc.M112.435909 |
0.396 |
|
| 2013 |
Weiser BP, Kelz MB, Eckenhoff RG. In vivo activation of azipropofol prolongs anesthesia and reveals synaptic targets Journal of Biological Chemistry. 288: 1279-1285. PMID 23184948 DOI: 10.1074/Jbc.M112.413989 |
0.395 |
|
| 2013 |
Jayakar SS, Zhou X, Dostalova Z, Dailey WP, Miller KW, Eckenhoff RG, Cohen JB. Identifying the Propofol Binding Site(S) in Heterologously Expressed Human Alpha1 Beta3 Gaba-A Receptors using a Photoreactive Propofol Analog Biophysical Journal. 104: 637a. DOI: 10.1016/J.Bpj.2012.11.3519 |
0.365 |
|
| 2012 |
Yuki K, Bu W, Xi J, Sen M, Shimaoka M, Eckenhoff RG. Isoflurane binds and stabilizes a closed conformation of the leukocyte function-associated antigen-1. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 4408-17. PMID 22815384 DOI: 10.1096/Fj.12-212746 |
0.428 |
|
| 2012 |
LeBard DN, Hénin J, Eckenhoff RG, Klein ML, Brannigan G. General anesthetics predicted to block the GLIC pore with micromolar affinity Plos Computational Biology. 8. PMID 22693438 DOI: 10.1371/Journal.Pcbi.1002532 |
0.671 |
|
| 2012 |
Oakley S, Vedula LS, Bu W, Meng QC, Xi J, Liu R, Eckenhoff RG, Loll PJ. Recognition of anesthetic barbiturates by a protein binding site: a high resolution structural analysis. Plos One. 7: e32070. PMID 22359658 DOI: 10.1371/Journal.Pone.0032070 |
0.446 |
|
| 2012 |
Cui T, Mowrey D, Bondarenko V, Tillman T, Ma D, Landrum E, Perez-Aguilar JM, He J, Wang W, Saven JG, Eckenhoff RG, Tang P, Xu Y. NMR structure and dynamics of a designed water-soluble transmembrane domain of nicotinic acetylcholine receptor. Biochimica Et Biophysica Acta. 1818: 617-26. PMID 22155685 DOI: 10.1016/J.Bbamem.2011.11.021 |
0.393 |
|
| 2011 |
Barber AF, Liang Q, Amaral C, Eckenhoff RG, Treptow W, Covarrubias M. Visualization of the General Anesthetic Site in a K+ Channel Biophysical Journal. 100: 100a. DOI: 10.1016/J.Bpj.2010.12.755 |
0.396 |
|
| 2011 |
Brannigan G, Henin J, Eckenhoff R, Klein M. Transmembrane Domain Packing in Cys-Loop Receptors: What Can we Learn from Prokaryotes? Biophysical Journal. 100: 277a. DOI: 10.1016/J.Bpj.2010.12.1722 |
0.61 |
|
| 2011 |
LeBard D, Brannigan G, Henin J, Eckenhoff R, Klein M. Dominant Site Involved in Inhibition of Targets by Anesthetics Suggested Through Novel Free Energy Perturbation Calculations Biophysical Journal. 100: 195a. DOI: 10.1016/J.Bpj.2010.12.1282 |
0.67 |
|
| 2010 |
Brannigan G, LeBard DN, Hénin J, Eckenhoff RG, Klein ML. Multiple binding sites for the general anesthetic isoflurane identified in the nicotinic acetylcholine receptor transmembrane domain Proceedings of the National Academy of Sciences of the United States of America. 107: 14122-14127. PMID 20660787 DOI: 10.1073/Pnas.1008534107 |
0.669 |
|
| 2010 |
Hall MA, Xi J, Lor C, Dai S, Pearce R, Dailey WP, Eckenhoff RG. m-Azipropofol (AziPm) a photoactive analogue of the intravenous general anesthetic propofol. Journal of Medicinal Chemistry. 53: 5667-75. PMID 20597506 DOI: 10.1021/Jm1004072 |
0.374 |
|
| 2010 |
Eckenhoff RG, Xi J, Dailey WP. Inhalational anesthetic photolabeling. Methods in Molecular Biology (Clifton, N.J.). 617: 437-43. PMID 20336439 DOI: 10.1007/978-1-60327-323-7_31 |
0.342 |
|
| 2010 |
Eckenhoff RG, Xi J, Shimaoka M, Bhattacharji A, Covarrubias M, Dailey WP. Azi-isoflurane, a Photolabel Analog of the Commonly Used Inhaled General Anesthetic Isoflurane. Acs Chemical Neuroscience. 1: 139-145. PMID 20228895 DOI: 10.1021/Cn900014M |
0.437 |
|
| 2010 |
Hénin J, Brannigan G, Dailey WP, Eckenhoff R, Klein ML. An atomistic model for simulations of the general anesthetic isoflurane. The Journal of Physical Chemistry. B. 114: 604-12. PMID 19924847 DOI: 10.1021/Jp9088035 |
0.624 |
|
| 2010 |
Brannigan G, Lebard D, Henin J, Eckenhoff R, Klein ML. Multiple Modes of Interaction between the Nicotinic Acetylcholine Receptor and Isoflurane Observed Through Long Time Simulations Biophysical Journal. 98: 134a. DOI: 10.1016/J.Bpj.2009.12.722 |
0.677 |
|
| 2010 |
LeBard DN, Brannigan G, Hénin J, Eckenhoff R, Klein ML. Effects of Isoflurane Binding in the Pore of a Ligand-Gated Ion Channel Biophysical Journal. 98: 133a. DOI: 10.1016/J.Bpj.2009.12.719 |
0.642 |
|
| 2009 |
Vedula LS, Brannigan G, Economou NJ, Xi J, Hall MA, Liu R, Rossi MJ, Dailey WP, Grasty KC, Klein ML, Eckenhoff RG, Loll PJ. A unitary anesthetic binding site at high resolution. The Journal of Biological Chemistry. 284: 24176-84. PMID 19605349 DOI: 10.1074/Jbc.M109.017814 |
0.67 |
|
| 2009 |
Ebalunode JO, Dong X, Ouyang Z, Liang J, Eckenhoff RG, Zheng W. Structure-based shape pharmacophore modeling for the discovery of novel anesthetic compounds. Bioorganic & Medicinal Chemistry. 17: 5133-8. PMID 19520579 DOI: 10.1016/J.Bmc.2009.05.060 |
0.334 |
|
| 2009 |
Butts CA, Xi J, Brannigan G, Saad AA, Venkatachalan SP, Pearce RA, Klein ML, Eckenhoff RG, Dmochowski IJ. Identification of a fluorescent general anesthetic, 1-aminoanthracene. Proceedings of the National Academy of Sciences of the United States of America. 106: 6501-6. PMID 19346473 DOI: 10.1073/Pnas.0810590106 |
0.585 |
|
| 2009 |
Cui T, Tang P, Saven JG, Eckenhoff RG, Xu Y. NMR Structure of Water-Solubilized Transmembrane Domain of Nicotinic Acetylcholine Receptor Biophysical Journal. 96: 429a. DOI: 10.1016/J.Bpj.2008.12.2197 |
0.318 |
|
| 2008 |
Brannigan G, Hénin J, Law R, Eckenhoff R, Klein ML. Embedded cholesterol in the nicotinic acetylcholine receptor Proceedings of the National Academy of Sciences of the United States of America. 105: 14418-14423. PMID 18768796 DOI: 10.1073/Pnas.0803029105 |
0.649 |
|
| 2007 |
Hill PA, Wei Q, Eckenhoff RG, Dmochowski IJ. Thermodynamics of xenon binding to cryptophane in water and human plasma. Journal of the American Chemical Society. 129: 9262-3. PMID 17616197 DOI: 10.1021/Ja072965P |
0.309 |
|
| 2007 |
Pan JZ, Xi J, Tobias JW, Eckenhoff MF, Eckenhoff RG. Halothane binding proteome in human brain cortex. Journal of Proteome Research. 6: 582-92. PMID 17269715 DOI: 10.1021/Pr060311U |
0.347 |
|
| 2006 |
Xi J, Liu R, Rossi MJ, Yang J, Loll PJ, Dailey WP, Eckenhoff RG. Photoactive analogues of the haloether anesthetics provide high-resolution features from low-affinity interactions. Acs Chemical Biology. 1: 377-84. PMID 17163775 DOI: 10.1021/Cb600207D |
0.427 |
|
| 2006 |
Vemparala S, Saiz L, Eckenhoff RG, Klein ML. Partitioning of anesthetics into a lipid bilayer and their interaction with membrane-bound peptide bundles. Biophysical Journal. 91: 2815-25. PMID 16877515 DOI: 10.1529/Biophysj.106.085324 |
0.35 |
|
| 2005 |
Peterlin Z, Ishizawa Y, Araneda R, Eckenhoff R, Firestein S. Selective activation of G-protein coupled receptors by volatile anesthetics. Molecular and Cellular Neurosciences. 30: 506-12. PMID 16185894 DOI: 10.1016/J.Mcn.2005.08.012 |
0.334 |
|
| 2005 |
Mohr JT, Gribble GW, Lin SS, Eckenhoff RG, Cantor RS. Anesthetic potency of two novel synthetic polyhydric alkanols longer than the n-alkanol cutoff: evidence for a bilayer-mediated mechanism of anesthesia? Journal of Medicinal Chemistry. 48: 4172-6. PMID 15943489 DOI: 10.1021/Jm049459K |
0.316 |
|
| 2005 |
Liu R, Eckenhoff RG. Weak Polar Interactions Confer Albumin Binding Site Selectivity for Haloether Anesthetics Anesthesiology. 102: 799-805. PMID 15791110 DOI: 10.1097/00000542-200504000-00016 |
0.411 |
|
| 2005 |
Liu R, Loll PJ, Eckenhoff RG. Structural basis for high-affinity volatile anesthetic binding in a natural 4-helix bundle protein. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 567-76. PMID 15791007 DOI: 10.1096/Fj.04-3171Com |
0.44 |
|
| 2005 |
Johansson JS, Manderson GA, Ramoni R, Grolli S, Eckenhoff RG. Binding of the volatile general anesthetics halothane and isoflurane to a mammalian β‐barrel protein Febs Journal. 272: 573-581. PMID 15654894 DOI: 10.1111/J.1742-4658.2004.04500.X |
0.391 |
|
| 2005 |
Liu R, Yang J, Ha CE, Bhagavan NV, Eckenhoff RG. Truncated human serum albumin retains general anaesthetic binding activity. The Biochemical Journal. 388: 39-45. PMID 15634193 DOI: 10.1042/Bj20041224 |
0.426 |
|
| 2005 |
Liu R, Eckenhoff RG. Interaction between Anesthetic Molecules and Their Binding Sites Must Be Far More Complex Anesthesiology. 103: 1102-1102. DOI: 10.1097/00000542-200511000-00031 |
0.373 |
|
| 2004 |
Xi J, Liu R, Asbury GR, Eckenhoff MF, Eckenhoff RG. Inhalational Anesthetic-binding Proteins in Rat Neuronal Membranes Journal of Biological Chemistry. 279: 19628-19633. PMID 14988400 DOI: 10.1074/Jbc.M313864200 |
0.402 |
|
| 2004 |
Liu R, Meng Q, Xi J, Yang J, Ha CE, Bhagavan NV, Eckenhoff RG. Comparative binding character of two general anaesthetics for sites on human serum albumin. The Biochemical Journal. 380: 147-52. PMID 14759223 DOI: 10.1042/Bj20031652 |
0.41 |
|
| 2003 |
Chiara DC, Dangott LJ, Eckenhoff RG, Cohen JB. Identification of nicotinic acetylcholine receptor amino acids photolabeled by the volatile anesthetic halothane. Biochemistry. 42: 13457-67. PMID 14621991 DOI: 10.1021/Bi0351561 |
0.383 |
|
| 2002 |
Liu R, Pidikiti R, Ha CE, Petersen CE, Bhagavan NV, Eckenhoff RG. The role of electrostatic interactions in human serum albumin binding and stabilization by halothane. The Journal of Biological Chemistry. 277: 36373-9. PMID 12118010 DOI: 10.1074/Jbc.M205479200 |
0.395 |
|
| 2002 |
Ishizawa Y, Pidikiti R, Liebman PA, Eckenhoff RG. G protein-coupled receptors as direct targets of inhaled anesthetics. Molecular Pharmacology. 61: 945-52. PMID 11961111 DOI: 10.1124/Mol.61.5.945 |
0.431 |
|
| 2002 |
Eckenhoff RG, Knoll FJ, Greenblatt EP, Dailey WP. Halogenated diazirines as photolabel mimics of the inhaled haloalkane anesthetics. Journal of Medicinal Chemistry. 45: 1879-86. PMID 11960499 DOI: 10.1021/Jm0104926 |
0.319 |
|
| 2002 |
Chan K, Meng QC, Johansson JS, Eckenhoff RG. Low-affinity analytical chromatography for measuring inhaled anesthetic binding to isolated proteins. Analytical Biochemistry. 301: 308-313. PMID 11814301 DOI: 10.1006/Abio.2001.5506 |
0.405 |
|
| 2002 |
Eckenhoff MF, Chan K, Eckenhoff RG. Multiple specific binding targets for inhaled anesthetics in the mammalian brain. Journal of Pharmacology and Experimental Therapeutics. 300: 172-179. PMID 11752113 DOI: 10.1124/Jpet.300.1.172 |
0.358 |
|
| 2002 |
Johansson JS, Manderson GA, Pidikiti R, Eckenhoff RG. Binding of Four General Anesthetics to the Hydrophobic Core of a Four-Alpha-Helix Bundle Protein: [2002][A-79] Anesthesiology. 96. DOI: 10.1097/00000542-200209002-00079 |
0.333 |
|
| 2001 |
Eckenhoff RG, Pidikiti R, Reddy KS. Anesthetic stabilization of protein intermediates: myoglobin and halothane. Biochemistry. 40: 10819-10824. PMID 11535057 DOI: 10.1021/Bi010691R |
0.386 |
|
| 2001 |
Tanner JW, Johansson JS, Liebman PA, Eckenhoff RG. Predictability of Weak Binding from X-ray Crystallography: Inhaled Anesthetics and Myoglobin† Biochemistry. 40: 5075-5080. PMID 11305924 DOI: 10.1021/Bi001428D |
0.358 |
|
| 2001 |
Eckenhoff RG, Tanner JW, Liebman PA. Cooperative binding of inhaled anesthetics and ATP to firefly luciferase. Proteins. 42: 436-441. PMID 11170198 DOI: 10.1002/1097-0134(20010301)42:4<436::Aid-Prot20>3.0.Co;2-I |
0.394 |
|
| 2000 |
Ishizawa Y, Sharp R, Liebman PA, Eckenhoff RG. Halothane binding to a G protein coupled receptor in retinal membranes by photoaffinity labeling. Biochemistry. 39: 8497-8502. PMID 10913255 DOI: 10.1021/Bi0001776 |
0.354 |
|
| 2000 |
Eckenhoff RG, Petersen CE, Ha CE, Bhagavan NV. Inhaled anesthetic binding sites in human serum albumin. The Journal of Biological Chemistry. 275: 30439-44. PMID 10896670 DOI: 10.1074/Jbc.M005052200 |
0.427 |
|
| 2000 |
Tang P, Eckenhoff RG, Xu Y. General anesthetic binding to gramicidin A: the structural requirements. Biophysical Journal. 78: 1804-9. PMID 10733961 DOI: 10.1016/S0006-3495(00)76730-0 |
0.349 |
|
| 2000 |
Johansson JS, Scharf D, Davies LA, Reddy KS, Eckenhoff RG. A Designed Four-α-Helix Bundle That Binds the Volatile General Anesthetic Halothane with High Affinity Biophysical Journal. 78: 982-993. PMID 10653811 DOI: 10.1016/S0006-3495(00)76656-2 |
0.439 |
|
| 2000 |
Ishizawa Y, Liebman PA, Eckenhoff RG. Room 302, 10/16/2000 9: 00 AM - 10: 30 AM (PD) Direct Interaction of Halothane with a Ligand Binding Site in a G Protein Coupled Receptor A-122 Anesthesiology. 93. DOI: 10.1097/00000542-200009001-00122 |
0.37 |
|
| 2000 |
Ishizawa Y, Johansson JS, Liebman PA, Eckenhoff RG. Room 302, 10/16/2000 9: 00 AM - 10: 30 AM (PD) Differential Anesthetic Binding to a G Protein Coupled Receptor Demonstrated Using Tryptophan Fluorescence A-119 Anesthesiology. 93. DOI: 10.1097/00000542-200009001-00119 |
0.328 |
|
| 1999 |
Eckenhoff RG, Tanner JW, Johansson JS. Steric Hindrance Is Not Required for n-Alkanol Cutoff in Soluble Proteins Molecular Pharmacology. 56: 414-418. PMID 10419562 DOI: 10.1124/Mol.56.2.414 |
0.373 |
|
| 1998 |
Eckenhoff RG, Tanner JW. Differential Halothane Binding and Effects on Serum Albumin and Myoglobin Biophysical Journal. 75: 477-483. PMID 9649409 DOI: 10.1016/S0006-3495(98)77536-8 |
0.425 |
|
| 1997 |
Kosk-Kosicka D, Fomitcheva I, Lopez MM, Eckenhoff RG. Heterogeneous halothane binding in the SR Ca2+-ATPase Febs Letters. 402: 189-192. PMID 9037193 DOI: 10.1016/S0014-5793(96)01526-8 |
0.376 |
|
| 1996 |
Eckenhoff RG. Amino Acid Resolution of Halothane Binding Sites in Serum Albumin Journal of Biological Chemistry. 271: 15521-15526. PMID 8663164 DOI: 10.1074/Jbc.271.26.15521 |
0.409 |
|
| 1996 |
Johansson JS, Eckenhoff RG. Minimum structural requirement for an inhalational anesthetic binding site on a protein target. Biochimica Et Biophysica Acta. 1290: 63-68. PMID 8645708 DOI: 10.1016/0304-4165(95)00187-5 |
0.311 |
|
| 1996 |
Eckenhoff RG. An inhalational anesthetic binding domain in the nicotinic acetylcholine receptor Proceedings of the National Academy of Sciences of the United States of America. 93: 2807-2810. PMID 8610122 DOI: 10.1073/Pnas.93.7.2807 |
0.385 |
|
| 1995 |
Johansson JS, Eckenhoff RG, Dutton PL. Binding of halothane to serum albumin demonstrated using tryptophan fluorescence. Anesthesiology. 83: 316-24. PMID 7631954 DOI: 10.1097/00000542-199508000-00012 |
0.4 |
|
| 1994 |
Eckenhoff RG, Fagan D. Inhalation anaesthetic competition at high-affinity cocaine binding sites in rat brain synaptosomes Bja: British Journal of Anaesthesia. 73: 820-825. PMID 7880673 DOI: 10.1093/Bja/73.6.820 |
0.355 |
|
| 1994 |
Johansson JS, Eckenhoff RG, Dutton PL. Saturatable Binding Of Halothane To Serum Albumin Demonstrated Using Tryptophan Fluorescence Anesthesiology. 81. DOI: 10.1097/00000542-199409001-00467 |
0.324 |
|
| 1993 |
Eckenhoff RG, Shuman H. Halothane binding to soluble proteins determined by photoaffinity labeling. Anesthesiology. 79: 96-106. PMID 7688197 DOI: 10.1097/00000542-199307000-00015 |
0.419 |
|
| 1992 |
El-Maghrabi EA, Eckenhoff RG, Shuman H. Saturable binding of halothane to rat brain synaptosomes. Proceedings of the National Academy of Sciences of the United States of America. 89: 4329-4332. PMID 1584767 DOI: 10.1073/Pnas.89.10.4329 |
0.419 |
|
| 1991 |
EL-Maghrabi EA, Eckenhoff RG, Shuman H. Saturable Binding Of Halothane To Synaptosomal Membranes Of Rat Brain Anesthesiology. 75. DOI: 10.1097/00000542-199109001-00373 |
0.303 |
|
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