Keith L. Brain - Publications

Affiliations: 
University of Birmingham (UK) 
Area:
Autonomic Neuroscience

34/68 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Hansen T, Tarasova OS, Khammy MM, Ferreira A, Kennard JA, Andresen J, Staehr C, Brain KL, Nilsson H, Aalkjaer C. [Ca ] changes in sympathetic varicosities and Schwann cells in rat mesenteric arteries - relation to noradrenaline release and contraction. Acta Physiologica (Oxford, England). e13279. PMID 30957955 DOI: 10.1111/Apha.13279  0.404
2018 Appukuttan S, Padmakumar M, Young JS, Brain KL, Manchanda R. Investigation of the Syncytial Nature of Detrusor Smooth Muscle as a Determinant of Action Potential Shape. Frontiers in Physiology. 9: 1300. PMID 30294280 DOI: 10.3389/Fphys.2018.01300  0.314
2018 Mahapatra C, Brain KL, Manchanda R. A biophysically constrained computational model of the action potential of mouse urinary bladder smooth muscle. Plos One. 13: e0200712. PMID 30048468 DOI: 10.1371/Journal.Pone.0200712  0.317
2018 Padmakumar M, Brain KL, Young JS, Manchanda R. A four-component model of the action potential in mouse detrusor smooth muscle cell. Plos One. 13: e0190016. PMID 29351282 DOI: 10.1371/Journal.Pone.0190016  0.304
2016 Lu Z, Chouhan AK, Borycz JA, Lu Z, Rossano AJ, Brain KL, Zhou Y, Meinertzhagen IA, Macleod GT. High-Probability Neurotransmitter Release Sites Represent an Energy-Efficient Design. Current Biology : Cb. PMID 27593375 DOI: 10.1016/J.Cub.2016.07.032  0.633
2012 Kobayter S, Young JS, Brain KL. Prostaglandin E 2 induces spontaneous rhythmic activity in mouse urinary bladder independently of efferent nerves British Journal of Pharmacology. 165: 401-413. PMID 21671904 DOI: 10.1111/J.1476-5381.2011.01543.X  0.421
2011 Williams DJ, Sidaway P, Cunnane TC, Brain KL. Mechanisms involved in nicotinic acetylcholine receptor-induced neurotransmitter release from sympathetic nerve terminals in the mouse vas deferens. Plos One. 6: e29209. PMID 22216213 DOI: 10.1371/Journal.Pone.0029209  0.651
2011 Brading AF, Brain KL. Ion channel modulators and urinary tract function. Handbook of Experimental Pharmacology. 375-93. PMID 21290236 DOI: 10.1007/978-3-642-16499-6_18  0.319
2009 Young JS, Amos RJ, Brain KL. Focal Ca2+ transient detection in smooth muscle Journal of Visualized Experiments : Jove. PMID 19564842 DOI: 10.3791/1247  0.448
2009 Valeri A, Brain KL, Young JS, Sgaragli G, Pessina F. Effects of 17beta-oestradiol on rat detrusor smooth muscle contractility. Experimental Physiology. 94: 834-46. PMID 19395661 DOI: 10.1113/Expphysiol.2009.047118  0.378
2009 Rahman F, Manchanda R, Brain KL. Prejunctional and postjunctional actions of heptanol and 18 beta-glycyrretinic acid in the rodent vas deferens. Autonomic Neuroscience : Basic & Clinical. 148: 69-75. PMID 19375392 DOI: 10.1016/J.Autneu.2009.03.006  0.387
2009 Brain KL. Neuroeffector Ca2+ transients for the direct measurement of purine release and indirect measurement of cotransmitters in rodents. Experimental Physiology. 94: 25-30. PMID 18805863 DOI: 10.1113/Expphysiol.2008.043679  0.474
2008 Young JS, Meng E, Cunnane TC, Brain KL. Spontaneous purinergic neurotransmission in the mouse urinary bladder. The Journal of Physiology. 586: 5743-55. PMID 18936079 DOI: 10.1113/Jphysiol.2008.162040  0.447
2008 Brain KL, Cunnane TC. Bretylium abolishes neurotransmitter release without necessarily abolishing the nerve terminal action potential in sympathetic terminals. British Journal of Pharmacology. 153: 831-9. PMID 18071295 DOI: 10.1038/Sj.Bjp.0707623  0.394
2008 Zhu HL, Brain KL, Aishima M, Shibata A, Young JS, Sueishi K, Teramoto N. Actions of two main metabolites of propiverine (M-1 and M-2) on voltage-dependent L-type Ca2+ currents and Ca2+ transients in murine urinary bladder myocytes. The Journal of Pharmacology and Experimental Therapeutics. 324: 118-27. PMID 17928569 DOI: 10.1124/Jpet.107.130021  0.364
2007 Young JS, Brain KL, Cunnane TC. Electrical and optical study of nerve impulse-evoked ATP-induced, P2X-receptor-mediated sympathetic neurotransmission at single smooth muscle cells in mouse isolated VAS deferens. Neuroscience. 148: 82-91. PMID 17629625 DOI: 10.1016/J.Neuroscience.2007.05.044  0.439
2007 Williams DJ, Brain KL, Cunnane TC. The effect of epibatidine on spontaneous and evoked neurotransmitter release in the mouse and guinea pig isolated vas deferens. British Journal of Pharmacology. 150: 906-12. PMID 17325648 DOI: 10.1038/Sj.Bjp.0707183  0.582
2007 Young JS, Brain KL, Cunnane TC. The origin of the skewed amplitude distribution of spontaneous excitatory junction potentials in poorly coupled smooth muscle cells. Neuroscience. 145: 153-61. PMID 17208381 DOI: 10.1016/J.Neuroscience.2006.11.054  0.382
2007 Amos RJ, Cunnane TC, Brain KL. Simultaneous electrophysiology and Ca2+ imaging during neurotransmission in rat anococcygeus smooth muscle Autonomic Neuroscience: Basic and Clinical. 135: 41-42. DOI: 10.1016/J.Autneu.2007.06.054  0.341
2005 Webster RG, Brain KL, Wilson RH, Grem JL, Vincent A. Oxaliplatin induces hyperexcitability at motor and autonomic neuromuscular junctions through effects on voltage-gated sodium channels. British Journal of Pharmacology. 146: 1027-39. PMID 16231011 DOI: 10.1038/Sj.Bjp.0706407  0.362
2003 Brain KL, Cuprian AM, Williams DJ, Cunnane TC. The sources and sequestration of Ca(2+) contributing to neuroeffector Ca(2+) transients in the mouse vas deferens. The Journal of Physiology. 553: 627-35. PMID 14500773 DOI: 10.1113/Jphysiol.2003.049734  0.621
2002 Brain KL, Jackson VM, Trout SJ, Cunnane TC. Intermittent ATP release from nerve terminals elicits focal smooth muscle Ca2+ transients in mouse vas deferens Journal of Physiology. 541: 849-862. PMID 12068045 DOI: 10.1113/Jphysiol.2002.019612  0.503
2001 Jackson VM, Trout SJ, Brain KL, Cunnane TC. Characterization of action potential-evoked calcium transients in mouse postganglionic sympathetic axon bundles Journal of Physiology. 537: 3-16. PMID 11711556 DOI: 10.1111/J.1469-7793.2001.0003K.X  0.415
2001 Brain KL, Trout SJ, Jackson VM, Dass N, Cunnane TC. Nicotine induces calcium spikes in single nerve terminal varicosities: A role for intracellular calcium stores Neuroscience. 106: 395-403. PMID 11566509 DOI: 10.1016/S0306-4522(01)00280-9  0.405
1999 O'Connor SC, Brain KL, Bennett MR. Individual sympathetic varicosities possess different sensitivities to alpha 2 and P2 receptor agonists and antagonists in mouse vas deferens. British Journal of Pharmacology. 128: 1739-53. PMID 10588930 DOI: 10.1038/Sj.Bjp.0702984  0.541
1999 Lengyel I, Olesen LE, Nichol KA, Brain KL, Wang X, Robinson PJ, Bennett MR, Rostas JA. Phosphorylation of proteins in chick ciliary ganglion under conditions that induce long-lasting changes in synaptic transmission: phosphoprotein targets for nitric oxide action. Neuroscience. 90: 607-19. PMID 10215163 DOI: 10.1016/S0306-4522(98)00452-7  0.475
1998 Bennett MR, Cheung A, Brain KL. Sympathetic neuromuscular transmission at a varicosity in a syncytium. Microscopy Research and Technique. 42: 433-50. PMID 9817550 DOI: 10.1002/(Sici)1097-0029(19980915)42:6<433::Aid-Jemt6>3.0.Co;2-N  0.539
1998 Lin YQ, Brain KL, Bennett MR. Calcium in sympathetic boutons of rat superior cervical ganglion during facilitation, augmentation and potentiation. Journal of the Autonomic Nervous System. 73: 26-37. PMID 9808368 DOI: 10.1016/S0165-1838(98)00108-8  0.563
1998 Brain KL, Bennett MR. Calcium transients evoked by action potentials in the somata of chick ciliary neurons. Journal of the Autonomic Nervous System. 71: 120-33. PMID 9760048 DOI: 10.1016/S0165-1838(98)00066-6  0.537
1997 Bennett MR, Brain K. Autonomic synaptic transmission at single boutons and calyces. Journal of Neurocytology. 26: 577-603. PMID 9352445 DOI: 10.1023/A:1018537625551  0.449
1997 Brain KL, Cottee LJ, Bennett MR. Varicosities of single sympathetic nerve terminals possess syntaxin zones and different synaptotagmin N-terminus labelling following stimulation. Journal of Neurocytology. 26: 491-500. PMID 9306247 DOI: 10.1023/A:1018533524643  0.49
1997 Brain KL, Bennett MR. Calcium in sympathetic varicosities of mouse vas deferens during facilitation, augmentation and autoinhibition. The Journal of Physiology. 502: 521-36. PMID 9279805 DOI: 10.1111/J.1469-7793.1997.521Bj.X  0.582
1996 Lin YQ, Brain KL, Nichol KA, Morgan JJ, Bennett MR. Vesicle-associated proteins and calcium in nerve terminals of chick ciliary ganglia during development of facilitation. The Journal of Physiology. 497: 639-56. PMID 9003550 DOI: 10.1113/Jphysiol.1996.Sp021796  0.527
1995 Brain KL, Bennett MR. Calcium in the nerve terminals of chick ciliary ganglia during facilitation, augmentation and potentiation. The Journal of Physiology. 489: 637-48. PMID 8788930 DOI: 10.1113/Jphysiol.1995.Sp021079  0.555
Low-probability matches (unlikely to be authored by this person)
2010 Brain KL. Parasympathetic cholinergic transmission, minus the vesicles. Experimental Physiology. 95: 263-4. PMID 20150402 DOI: 10.1113/Expphysiol.2009.050559  0.295
2015 Appukuttan S, Brain KL, Manchanda R. A computational model of urinary bladder smooth muscle syncytium : validation and investigation of electrical properties. Journal of Computational Neuroscience. 38: 167-87. PMID 25292316 DOI: 10.1007/S10827-014-0532-6  0.294
2017 Appukuttan S, Padmakumar M, Brain KL, Manchanda R. A Method for the Analysis of AP Foot Convexity: Insights into Smooth Muscle Biophysics. Frontiers in Bioengineering and Biotechnology. 5: 64. PMID 29124054 DOI: 10.3389/Fbioe.2017.00064  0.292
2011 Brain KL. Optical techniques for monitoring norepinephrine, and vesicular monoamine, transporter rates in sympathetic nerve terminals of mouse vas deferens Autonomic Neuroscience: Basic and Clinical. 163: 68-69. DOI: 10.1016/J.Autneu.2011.05.088  0.291
2019 Cao LL, Holmes AP, Marshall JM, Fabritz L, Brain KL. Dynamic monitoring of single-terminal norepinephrine transporter rate in the rodent cardiovascular system: A novel fluorescence imaging method. Autonomic Neuroscience : Basic & Clinical. 223: 102611. PMID 31901784 DOI: 10.1016/J.Autneu.2019.102611  0.284
2014 Yu TY, Syeda F, Holmes AP, Osborne B, Dehghani H, Brain KL, Kirchhof P, Fabritz L. An automated system using spatial oversampling for optical mapping in murine atria. Development and validation with monophasic and transmembrane action potentials. Progress in Biophysics and Molecular Biology. 115: 340-8. PMID 25130572 DOI: 10.1016/J.Pbiomolbio.2014.07.012  0.273
2010 Parker LK, Shanks JA, Kennard JA, Brain KL. Dynamic monitoring of NET activity in mature murine sympathetic terminals using a fluorescent substrate. British Journal of Pharmacology. 159: 797-807. PMID 20136837 DOI: 10.1111/J.1476-5381.2009.00574.X  0.26
2017 Yu TY, Dehghani H, Brain KL, Syeda F, Holmes A, Kirchhof P, Fabritz L. Optical mapping design for murine atrial electrophysiology Computer Methods in Biomechanics and Biomedical Engineering. Imaging & Visualization. 5: 368-376. DOI: 10.1080/21681163.2015.1081079  0.256
2009 Kennard JAG, Sachdev AR, Young JS, Brain KL. S14.5 The effects of Δ9-tetrahydrocannabinol on sympathetic cotransmission in the mouse vas deferens Autonomic Neuroscience: Basic and Clinical. 149: 49. DOI: 10.1016/J.Autneu.2009.05.074  0.254
2014 Yu TY, Syeda F, Dehghani H, Brain K, Kirchhof P, Fabritz L. 191 Advancement of Optical Mapping through Automated Algorithms and Second Generation CMOS Detectors to Reveal Murine Atrial Activation Patterns and Regional Variation of Action Potential Duration Heart. 100. DOI: 10.1136/Heartjnl-2014-306118.191  0.254
2011 Sidaway P, Brain KL. Real time monitoring of neurotransmitter uptake and storage in PC-12 cells: Implication for co-storage and co-transmission Autonomic Neuroscience: Basic and Clinical. 163: 69. DOI: 10.1016/J.Autneu.2011.05.089  0.25
2021 Cao LL, Marshall JM, Fabritz L, Brain KL. Resting cardiac sympathetic firing frequencies suppress terminal norepinephrine transporter uptake. Autonomic Neuroscience : Basic & Clinical. 232: 102794. PMID 33714751 DOI: 10.1016/j.autneu.2021.102794  0.249
2017 Appukuttan S, Brain KL, Manchanda R. Modeling extracellular fields for a three-dimensional network of cells using NEURON. Journal of Neuroscience Methods. 290: 27-38. PMID 28705695 DOI: 10.1016/J.Jneumeth.2017.07.005  0.234
2013 Newman AS, Batis N, Grafton G, Caputo F, Brady CA, Lambert JJ, Peters JA, Gordon J, Brain KL, Powell AD, Barnes NM. 5-Chloroindole: a potent allosteric modulator of the 5-HT₃ receptor. British Journal of Pharmacology. 169: 1228-38. PMID 23594147 DOI: 10.1111/Bph.12213  0.232
2012 Boersma AJ, Brain KL, Bayley H. Real-time stochastic detection of multiple neurotransmitters with a protein nanopore. Acs Nano. 6: 5304-8. PMID 22616662 DOI: 10.1021/Nn301125Y  0.227
2016 Holmes AP, Yu TY, Tull S, Syeda F, Kuhlmann SM, O'Brien SM, Patel P, Brain KL, Pavlovic D, Brown NA, Fabritz L, Kirchhof P. A Regional Reduction in Ito and IKACh in the Murine Posterior Left Atrial Myocardium Is Associated with Action Potential Prolongation and Increased Ectopic Activity. Plos One. 11: e0154077. PMID 27149380 DOI: 10.1371/Journal.Pone.0154077  0.222
2009 Kobayter S, Young JS, Brain KL. P3.7 Cellular mechanism of action of Prostaglandin E2 on mouse urinary bladder Autonomic Neuroscience: Basic and Clinical. 149: 84-85. DOI: 10.1016/J.Autneu.2009.05.155  0.222
2015 Sengupta N, Brain KL, Manchanda R. Spatiotemporal dynamics of synaptic drive in urinary bladder syncytium: A computational investigation. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2015: 8074-7. PMID 26738167 DOI: 10.1109/EMBC.2015.7320267  0.221
2007 Young JS, Brain KL, Cunnane TC. Measures of purinergic neurotransmission reveal variable effective packet size Autonomic Neuroscience: Basic and Clinical. 135: 116-117. DOI: 10.1016/J.Autneu.2007.06.199  0.215
2013 Boersma AJ, Sidaway P, Bayley H, Brain KL. Detecting purines, catecholamines and other transmitters with a mutant α-haemolysin pore one molecule at a time Autonomic Neuroscience: Basic and Clinical. 177: 315. DOI: 10.1016/J.Autneu.2013.08.053  0.214
1994 Sheppard CJR, Gu M, Brain K, Zhou H. Influence of spherical aberration on axial imaging of confocal reflection microscopy Applied Optics. 33: 616-624. PMID 20862056 DOI: 10.1364/Ao.33.000616  0.208
2006 Brain KL, Kay J, Shine B. Measurement of urinary metanephrines to screen for pheochromocytoma in an unselected hospital referral population. Clinical Chemistry. 52: 2060-4. PMID 16990424 DOI: 10.1373/Clinchem.2006.070805  0.194
2019 Padmakumar M, Brain K, Manchanda R. Analysis of spontaneous depolarization-linked hyperpolarizations in mouse detrusor smooth muscle cells Biomedical Research Journal. 6: 49. DOI: 10.4103/BMRJ.BMRJ_9_19  0.158
2011 Brain KL. Obituary: Professor Alison Brading, PhD Neurourology and Urodynamics. 30: 282-283. DOI: 10.1002/Nau.21086  0.154
2021 Appukuttan S, Brain KL, Manchanda R. Effect of Variations in Gap Junctional Coupling on the Frequency of Oscillatory Action Potentials in a Smooth Muscle Syncytium. Frontiers in Physiology. 12: 655225. PMID 34658901 DOI: 10.3389/fphys.2021.655225  0.154
2020 Alzahrani AA, Cao LL, Aldossary HS, Nathanael D, Fu J, Ray CJ, Brain KL, Kumar P, Coney AM, Holmes AP. β-Adrenoceptor blockade prevents carotid body hyperactivity and elevated vascular sympathetic nerve density induced by chronic intermittent hypoxia. Pflugers Archiv : European Journal of Physiology. PMID 33210151 DOI: 10.1007/s00424-020-02492-0  0.152
2017 Appukuttan S, Brain K, Manchanda R. Investigation of action potential propagation in a syncytium Biomedical Research Journal. 4: 102. DOI: 10.4103/2349-3666.240589  0.129
2015 Mahapatra C, Brain KL, Manchanda R. Computational studies on urinary bladder smooth muscle: Modeling ion channels and their role in generating electrical activity International Ieee/Embs Conference On Neural Engineering, Ner. 2015: 832-835. DOI: 10.1109/NER.2015.7146752  0.119
2015 Appukuttan S, Brain K, Manchanda R. Syncytial basis for diversity in spike shapes and their propagation in detrusor smooth muscle Procedia Computer Science. 51: 785-794. DOI: 10.1016/j.procs.2015.05.199  0.113
2015 Sengupta N, Brain KL, Manchanda R. Spatiotemporal dynamics of synaptic drive in urinary bladder syncytium: A computational investigation Proceedings of the Annual International Conference of the Ieee Engineering in Medicine and Biology Society, Embs. 2015: 8074-8077. DOI: 10.1109/EMBC.2015.7320267  0.102
2023 Saleeb-Mousa J, Nathanael D, Coney AM, Kalla M, Brain KL, Holmes AP. Mechanisms of Atrial Fibrillation in Obstructive Sleep Apnoea. Cells. 12. PMID 37371131 DOI: 10.3390/cells12121661  0.096
2008 Pearton M, Allender C, Brain K, Anstey A, Gateley C, Wilke N, Morrissey A, Birchall J. Gene delivery to the epidermal cells of human skin explants using microfabricated microneedles and hydrogel formulations. Pharmaceutical Research. 25: 407-16. PMID 17671832 DOI: 10.1007/s11095-007-9360-y  0.078
2006 Coulman SA, Barrow D, Anstey A, Gateley C, Morrissey A, Wilke N, Allender C, Brain K, Birchall JC. Minimally invasive cutaneous delivery of macromolecules and plasmid DNA via microneedles. Current Drug Delivery. 3: 65-75. PMID 16472095  0.074
2005 Birchall J, Coulman S, Pearton M, Allender C, Brain K, Anstey A, Gateley C, Wilke N, Morrissey A. Cutaneous DNA delivery and gene expression in ex vivo human skin explants via wet-etch micro-fabricated micro-needles. Journal of Drug Targeting. 13: 415-21. PMID 16308210 DOI: 10.1080/10611860500383705  0.021
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