Wayne Chadwick - Publications

Affiliations: 
2006-2010 Takeda Pharmaceuticals, Deerfield, IL, United States 

27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Van Gastel J, Cai H, Cong WN, Chadwick W, Daimon C, Leysen H, Hendrickx JO, De Schepper R, Vangenechten L, Van Turnhout J, Verswyvel J, Becker KG, Zhang Y, Lehrmann E, Wood WH, et al. Multidimensional informatic deconvolution defines gender-specific roles of hypothalamic GIT2 in aging trajectories. Mechanisms of Ageing and Development. 111150. PMID 31574270 DOI: 10.1016/J.Mad.2019.111150  0.693
2017 Janssens J, Lu D, Ni B, Chadwick W, Siddiqui S, Azmi A, Etienne H, Jushaj A, van Gastel J, Martin B, Maudsley S. Development of Precision Small-Molecule Proneurotrophic Therapies for Neurodegenerative Diseases. Vitamins and Hormones. 104: 263-311. PMID 28215298 DOI: 10.1016/Bs.Vh.2016.10.006  0.772
2015 Martin B, Chadwick W, Janssens J, Premont RT, Schmalzigaug R, Becker KG, Lehrmann E, Wood WH, Zhang Y, Siddiqui S, Park SS, Cong WN, Daimon CM, Maudsley S. GIT2 Acts as a Systems-Level Coordinator of Neurometabolic Activity and Pathophysiological Aging. Frontiers in Endocrinology. 6: 191. PMID 26834700 DOI: 10.3389/Fendo.2015.00191  0.796
2015 Cong WN, Chadwick W, Wang R, Daimon CM, Cai H, Amma J, Wood WH, Becker KG, Martin B, Maudsley S. Amitriptyline improves motor function via enhanced neurotrophin signaling and mitochondrial functions in the murine N171-82Q Huntington disease model. The Journal of Biological Chemistry. 290: 2728-43. PMID 25505248 DOI: 10.1074/Jbc.M114.588608  0.586
2013 Martin B, Chen H, Daimon CM, Chadwick W, Siddiqui S, Maudsley S. Plurigon: three dimensional visualization and classification of high-dimensionality data. Frontiers in Physiology. 4: 190. PMID 23885241 DOI: 10.3389/Fphys.2013.00190  0.721
2012 Stranahan AM, Martin B, Chadwick W, Park SS, Wang L, Becker KG, Woodiii WH, Zhang Y, Maudsley S. Metabolic context regulates distinct hypothalamic transcriptional responses to antiaging interventions. International Journal of Endocrinology. 2012: 732975. PMID 22934110 DOI: 10.1155/2012/732975  0.662
2012 Martin B, Chadwick W, Cong WN, Pantaleo N, Daimon CM, Golden EJ, Becker KG, Wood WH, Carlson OD, Egan JM, Maudsley S. Euglycemic agent-mediated hypothalamic transcriptomic manipulation in the N171-82Q model of Huntington disease is related to their physiological efficacy. The Journal of Biological Chemistry. 287: 31766-82. PMID 22822065 DOI: 10.1074/Jbc.M112.387316  0.747
2012 Chadwick W, Martin B, Chapter MC, Park SS, Wang L, Daimon CM, Brenneman R, Maudsley S. GIT2 acts as a potential keystone protein in functional hypothalamic networks associated with age-related phenotypic changes in rats. Plos One. 7: e36975. PMID 22606319 DOI: 10.1371/Journal.Pone.0036975  0.764
2012 Martin B, Chadwick W, Yi T, Park SS, Lu D, Ni B, Gadkaree S, Farhang K, Becker KG, Maudsley S. VENNTURE--a novel Venn diagram investigational tool for multiple pharmacological dataset analysis. Plos One. 7: e36911. PMID 22606307 DOI: 10.1371/Journal.Pone.0036911  0.762
2012 Chadwick W, Mitchell N, Martin B, Maudsley S. Therapeutic targeting of the endoplasmic reticulum in Alzheimer's disease. Current Alzheimer Research. 9: 110-9. PMID 22329655 DOI: 10.2174/156720512799015055  0.582
2012 Maudsley S, Chadwick W. Progressive and unconventional pharmacotherapeutic approaches to Alzheimer's disease therapy. Current Alzheimer Research. 9: 1-4. PMID 22329648 DOI: 10.2174/156720512799015082  0.531
2012 Martin B, Chadwick W, Yi T, Park S, Lu D, Ni B, Gadkaree S, Farhang K, Becker KG, Maudsley S. Correction: VENNTURE–A Novel Venn Diagram Investigational Tool for Multiple Pharmacological Dataset Analysis Plos One. 7. DOI: 10.1371/Annotation/27F1021C-B6F2-4B90-98Bc-Fcacd2679185  0.764
2011 Maudsley S, Chadwick W, Wang L, Zhou Y, Martin B, Park SS. Bioinformatic approaches to metabolic pathways analysis. Methods in Molecular Biology (Clifton, N.J.). 756: 99-130. PMID 21870222 DOI: 10.1007/978-1-61779-160-4_5  0.704
2011 Chadwick W, Mitchell N, Caroll J, Zhou Y, Park SS, Wang L, Becker KG, Zhang Y, Lehrmann E, Wood WH, Martin B, Maudsley S. Amitriptyline-mediated cognitive enhancement in aged 3×Tg Alzheimer's disease mice is associated with neurogenesis and neurotrophic activity. Plos One. 6: e21660. PMID 21738757 DOI: 10.1371/Journal.Pone.0021660  0.684
2011 Chadwick W, Boyle JP, Zhou Y, Wang L, Park SS, Martin B, Wang R, Becker KG, Wood WH, Zhang Y, Peers C, Maudsley S. Multiple oxygen tension environments reveal diverse patterns of transcriptional regulation in primary astrocytes. Plos One. 6: e21638. PMID 21738745 DOI: 10.1371/Journal.Pone.0021638  0.67
2011 Park SS, Stranahan AM, Chadwick W, Zhou Y, Wang L, Martin B, Becker KG, Maudsley S. Cortical gene transcription response patterns to water maze training in aged mice. Bmc Neuroscience. 12: 63. PMID 21714909 DOI: 10.1186/1471-2202-12-63  0.694
2011 Zhou Y, Yi T, Park SS, Chadwick W, Shen RF, Wu WW, Martin B, Maudsley S. Rapid and enhanced proteolytic digestion using electric-field-oriented enzyme reactor. Journal of Proteomics. 74: 1030-5. PMID 21338726 DOI: 10.1016/J.Jprot.2011.02.007  0.574
2011 Chadwick W, Keselman A, Park SS, Zhou Y, Wang L, Brenneman R, Martin B, Maudsley S. Repetitive peroxide exposure reveals pleiotropic mitogen-activated protein kinase signaling mechanisms. Journal of Signal Transduction. 2011: 636951. PMID 21258655 DOI: 10.1155/2011/636951  0.723
2011 Stranahan A, Chadwick W, Zhou Y, Park S, Wang L, Becker K, Wood W, Zhang Y, Martin B, Maudsley S. Wheel running and caloric restriction recruit distinct hypothalamic transcriptional profiles in wildtype and leptin receptor deficient mice Appetite. 57: S42. DOI: 10.1016/J.Appet.2011.05.275  0.701
2010 Chadwick W, Zhou Y, Park SS, Wang L, Mitchell N, Stone MD, Becker KG, Martin B, Maudsley S. Minimal peroxide exposure of neuronal cells induces multifaceted adaptive responses. Plos One. 5: e14352. PMID 21179406 DOI: 10.1371/Journal.Pone.0014352  0.753
2010 Chadwick W, Brenneman R, Martin B, Maudsley S. Complex and multidimensional lipid raft alterations in a murine model of Alzheimer's disease. International Journal of Alzheimer's Disease. 2010: 604792. PMID 21151659 DOI: 10.4061/2010/604792  0.74
2010 Pantaleo N, Chadwick W, Park SS, Wang L, Zhou Y, Martin B, Maudsley S. The mammalian tachykinin ligand-receptor system: an emerging target for central neurological disorders. Cns & Neurological Disorders Drug Targets. 9: 627-35. PMID 20632965 DOI: 10.2174/187152710793361504  0.758
2010 Wang L, Chadwick W, Park SS, Zhou Y, Silver N, Martin B, Maudsley S. Gonadotropin-releasing hormone receptor system: modulatory role in aging and neurodegeneration. Cns & Neurological Disorders Drug Targets. 9: 651-60. PMID 20632963 DOI: 10.2174/187152710793361559  0.79
2010 Martin B, Shin YK, White CM, Ji S, Kim W, Carlson OD, Napora JK, Chadwick W, Chapter M, Waschek JA, Mattson MP, Maudsley S, Egan JM. Vasoactive intestinal peptide-null mice demonstrate enhanced sweet taste preference, dysglycemia, and reduced taste bud leptin receptor expression. Diabetes. 59: 1143-52. PMID 20150284 DOI: 10.2337/Db09-0807  0.765
2010 Chapter MC, White CM, DeRidder A, Chadwick W, Martin B, Maudsley S. Chemical modification of Class II G protein-coupled receptor ligands: Frontiers in the development of peptide analogs as neuroendocrine pharmacological therapies Pharmacology and Therapeutics. 125: 39-54. PMID 19686775 DOI: 10.1016/J.Pharmthera.2009.07.006  0.74
2009 Martin B, Golden E, Carlson OD, Pistell P, Zhou J, Kim W, Frank BP, Thomas S, Chadwick WA, Greig NH, Bates GP, Sathasivam K, Bernier M, Maudsley S, Mattson MP, et al. Exendin-4 improves glycemic control, ameliorates brain and pancreatic pathologies, and extends survival in a mouse model of Huntington's disease. Diabetes. 58: 318-28. PMID 18984744 DOI: 10.2337/Db08-0799  0.552
2008 Chadwick W, Magnus T, Martin B, Keselman A, Mattson MP, Maudsley S. Targeting TNF-alpha receptors for neurotherapeutics. Trends in Neurosciences. 31: 504-11. PMID 18774186 DOI: 10.1016/J.Tins.2008.07.005  0.564
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