Nicholas E. Dixon - Publications

Affiliations: 
School of Chemistry and Molecular Bioscience University of Wollongong, Keiraville, New South Wales, Australia 

147 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Whinn KS, Xu ZQ, Jergic S, Sharma N, Spenkelink LM, Dixon NE, van Oijen AM, Ghodke H. Single-molecule visualization of stalled replication-fork rescue by the Escherichia coli Rep helicase. Nucleic Acids Research. PMID 36938885 DOI: 10.1093/nar/gkad186  0.698
2022 Kaur G, Spenkelink LM, Lewis JS, Jergic S, Dixon NE, van Oijen AM. Production of long linear DNA substrates with site-specific chemical lesions for single-molecule replisome studies. Methods in Enzymology. 672: 299-315. PMID 35934481 DOI: 10.1016/bs.mie.2022.02.022  0.681
2022 Paudel BP, Xu ZQ, Jergic S, Oakley AJ, Sharma N, Brown SHJ, Bouwer JC, Lewis PJ, Dixon NE, van Oijen AM, Ghodke H. Mechanism of transcription modulation by the transcription-repair coupling factor. Nucleic Acids Research. PMID 35641110 DOI: 10.1093/nar/gkac449  0.566
2021 Spinks RR, Spenkelink LM, Dixon NE, van Oijen AM. Single-Molecule Insights Into the Dynamics of Replicative Helicases. Frontiers in Molecular Biosciences. 8: 741718. PMID 34513934 DOI: 10.3389/fmolb.2021.741718  0.793
2021 Spinks RR, Spenkelink LM, Stratmann SA, Xu ZQ, Stamford NPJ, Brown SE, Dixon NE, Jergic S, van Oijen AM. DnaB helicase dynamics in bacterial DNA replication resolved by single-molecule studies. Nucleic Acids Research. PMID 34139009 DOI: 10.1093/nar/gkab493  0.792
2020 Monachino E, Jergic S, Lewis JS, Xu ZQ, Lo ATY, O'Shea VL, Berger JM, Dixon NE, van Oijen AM. A Primase-Induced Conformational Switch Controls the Stability of the Bacterial Replisome. Molecular Cell. PMID 32464091 DOI: 10.1016/J.Molcel.2020.04.037  0.706
2020 Dubiel K, Henry C, Spenkelink LM, Kozlov AG, Wood EA, Jergic S, Dixon NE, van Oijen AM, Cox MM, Lohman TM, Sandler SJ, Keck JL. Development of a single-stranded DNA-binding protein fluorescent fusion toolbox. Nucleic Acids Research. PMID 32374866 DOI: 10.1093/Nar/Gkaa320  0.711
2019 Chang S, Naiman K, Thrall ES, Kath JE, Jergic S, Dixon NE, Fuchs RP, Loparo JJ. A gatekeeping function of the replicative polymerase controls pathway choice in the resolution of lesion-stalled replisomes. Proceedings of the National Academy of Sciences of the United States of America. PMID 31796591 DOI: 10.1073/Pnas.1914485116  0.439
2019 Whinn KS, Kaur G, Lewis JS, Schauer GD, Mueller SH, Jergic S, Maynard H, Gan ZY, Naganbabu M, Bruchez MP, O'Donnell ME, Dixon NE, van Oijen AM, Ghodke H. Nuclease dead Cas9 is a programmable roadblock for DNA replication. Scientific Reports. 9: 13292. PMID 31527759 DOI: 10.1038/S41598-019-49837-Z  0.76
2019 McGrath AE, Martyn AP, Whittell LR, Dawes FE, El Salamouni NS, Beck JL, Dixon NE, Kelso MJ, Oakley AJ. Corrigendum to "Crystal structures and biochemical characterization of DNA sliding clamps from three Gram-negative bacterial pathogens" [J. Struct. Biol. 204 (3) (2018) 396-405]. Journal of Structural Biology. PMID 31097372 DOI: 10.1016/J.Jsb.2019.05.003  0.421
2019 Spenkelink LM, Lewis JS, Jergic S, Xu ZQ, Robinson A, Dixon NE, van Oijen AM. Recycling of single-stranded DNA-binding protein by the bacterial replisome. Nucleic Acids Research. PMID 30767010 DOI: 10.1093/Nar/Gkz090  0.725
2018 McGrath AE, Martyn AP, Whittell LR, Dawes FE, Beck JL, Dixon NE, Kelso MJ, Oakley AJ. Crystal structures and biochemical characterization of DNA sliding clamps from three Gram-negative bacterial pathogens. Journal of Structural Biology. PMID 30366028 DOI: 10.1016/J.Jsb.2018.10.008  0.447
2018 Xu ZQ, Dixon NE. Bacterial replisomes. Current Opinion in Structural Biology. 53: 159-168. PMID 30292863 DOI: 10.1016/j.sbi.2018.09.006  0.415
2018 Monachino E, Ghodke H, Spinks RR, Hoatson BS, Jergic S, Xu ZQ, Dixon NE, van Oijen AM. Design of DNA rolling-circle templates with controlled fork topology to study mechanisms of DNA replication. Analytical Biochemistry. PMID 30016625 DOI: 10.1016/J.Ab.2018.07.008  0.787
2018 Wegener KL, McGrath AE, Dixon NE, Oakley AJ, Scanlon DB, Abell AD, Bruning J. Rational design of a 310-helical PIP-box mimetic targeting PCNA - the human sliding clamp. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29917264 DOI: 10.1002/Chem.201801734  0.423
2018 Chilingaryan Z, Headey SJ, Lo ATY, Xu ZQ, Otting G, Dixon NE, Scanlon MJ, Oakley AJ. Fragment-Based Discovery of Inhibitors of the Bacterial DnaG-SSB Interaction. Antibiotics (Basel, Switzerland). 7. PMID 29470422 DOI: 10.3390/Antibiotics7010014  0.434
2017 Berghuis BA, Raducanu VS, Elshenawy MM, Jergic S, Depken M, Dixon NE, Hamdan SM, Dekker NH. What is all this fuss about Tus? Comparison of recent findings from biophysical and biochemical experiments. Critical Reviews in Biochemistry and Molecular Biology. 1-15. PMID 29108427 DOI: 10.1080/10409238.2017.1394264  0.535
2017 Park J, Jergic S, Jeon Y, Cho WK, Lee R, Dixon NE, Lee JB. Dynamics of Proofreading by the E. coli Pol III Replicase. Cell Chemical Biology. PMID 29104063 DOI: 10.1016/J.Chembiol.2017.09.008  0.451
2017 Lewis JS, Spenkelink LM, Jergic S, Wood EA, Monachino E, Horan NP, Duderstadt KE, Cox MM, Robinson A, Dixon NE, van Oijen AM. Single-molecule visualization of fast polymerase turnover in the bacterial replisome. Elife. 6. PMID 28432790 DOI: 10.7554/Elife.23932  0.717
2017 Lewis JS, Spenkelink LM, Jergic S, Wood EA, Monachino E, Horan NP, Duderstadt KE, Cox MM, Robinson A, Dixon NE, Oijen AMv. Author response: Single-molecule visualization of fast polymerase turnover in the bacterial replisome Elife. DOI: 10.7554/Elife.23932.027  0.303
2016 Lewis JS, Jergic S, Dixon NE. The E. coli DNA Replication Fork. The Enzymes. 39: 31-88. PMID 27241927 DOI: 10.1016/Bs.Enz.2016.04.001  0.579
2016 Dannatt HR, Felletti M, Jehle S, Wang Y, Emsley L, Dixon NE, Lesage A, Pintacuda G. Weak and Transient Protein Interactions Determined by Solid-State NMR. Angewandte Chemie (International Ed. in English). PMID 27101578 DOI: 10.1002/Anie.201511609  0.359
2016 Berghuis BA, Wassenburg JP, Wilschut JM, van Laar T, Dixon NE, Depken M, Dekker NH. Dissection of E.Coli DNA Replication in High Resolution with Temperature-Controlled Magnetic Tweezers Biophysical Journal. 110: 63a. DOI: 10.1016/J.Bpj.2015.11.407  0.512
2015 Kath JE, Chang S, Scotland MK, Wilbertz JH, Jergic S, Dixon NE, Sutton MD, Loparo JJ. Exchange between Escherichia coli polymerases II and III on a processivity clamp. Nucleic Acids Research. PMID 26657641 DOI: 10.1093/Nar/Gkv1375  0.484
2015 van Oijen AM, Dixon NE. Probing molecular choreography through single-molecule biochemistry. Nature Structural & Molecular Biology. 22: 948-52. PMID 26643847 DOI: 10.1038/Nsmb.3119  0.584
2015 Elshenawy MM, Jergic S, Xu ZQ, Sobhy MA, Takahashi M, Oakley AJ, Dixon NE, Hamdan SM. Replisome speed determines the efficiency of the Tus-Ter replication termination barrier. Nature. 525: 394-8. PMID 26322585 DOI: 10.1038/Nature14866  0.494
2015 Berghuis BA, Dulin D, Xu ZQ, van Laar T, Cross B, Janissen R, Jergic S, Dixon NE, Depken M, Dekker NH. Strand separation establishes a sustained lock at the Tus-Ter replication fork barrier. Nature Chemical Biology. PMID 26147356 DOI: 10.1038/Nchembio.1857  0.497
2015 Pandey M, Elshenawy MM, Jergic S, Takahashi M, Dixon NE, Hamdan SM, Patel SS. Two mechanisms coordinate replication termination by the Escherichia coli Tus-Ter complex. Nucleic Acids Research. PMID 26007657 DOI: 10.1093/Nar/Gkv527  0.475
2015 Yin Z, Whittell LR, Wang Y, Jergic S, Ma C, Lewis PJ, Dixon NE, Beck JL, Kelso MJ, Oakley AJ. Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs. Journal of Medicinal Chemistry. 58: 4693-702. PMID 25970224 DOI: 10.1021/Acs.Jmedchem.5B00232  0.457
2015 Monachino E, van der Valk RA, Jergic S, Dixon NE, Dame RT, van Oijen AM. How Does the Replication Machinery Deal with Roadblocks: A Single-Molecule Investigation Biophysical Journal. 108: 69a. DOI: 10.1016/J.Bpj.2014.11.412  0.575
2015 Oh J, Kim D, Cho W, Liu J, Jergic S, Dixon N, Fishel R, Lee J. Interplay MutS with β Clamp on Mismatched DNA Biophysical Journal. 108: 69a. DOI: 10.1016/J.Bpj.2014.11.409  0.528
2014 Cleverley RM, Barrett JR, Baslé A, Bui NK, Hewitt L, Solovyova A, Xu ZQ, Daniel RA, Dixon NE, Harry EJ, Oakley AJ, Vollmer W, Lewis RJ. Structure and function of a spectrin-like regulator of bacterial cytokinesis. Nature Communications. 5: 5421. PMID 25403286 DOI: 10.1038/Ncomms6421  0.316
2014 Cho WK, Jergic S, Kim D, Dixon NE, Lee JB. Loading dynamics of a sliding DNA clamp. Angewandte Chemie (International Ed. in English). 53: 6768-71. PMID 24854225 DOI: 10.1002/Anie.201403063  0.396
2014 Kath JE, Jergic S, Heltzel JM, Jacob DT, Dixon NE, Sutton MD, Walker GC, Loparo JJ. Polymerase exchange on single DNA molecules reveals processivity clamp control of translesion synthesis. Proceedings of the National Academy of Sciences of the United States of America. 111: 7647-52. PMID 24825884 DOI: 10.1073/Pnas.1321076111  0.535
2014 Yin Z, Wang Y, Whittell LR, Jergic S, Liu M, Harry E, Dixon NE, Kelso MJ, Beck JL, Oakley AJ. DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs. Chemistry & Biology. 21: 481-7. PMID 24631121 DOI: 10.1016/J.Chembiol.2014.02.009  0.516
2014 Su XC, Wang Y, Yagi H, Shishmarev D, Mason CE, Smith PJ, Vandevenne M, Dixon NE, Otting G. Bound or free: interaction of the C-terminal domain of Escherichia coli single-stranded DNA-binding protein (SSB) with the tetrameric core of SSB. Biochemistry. 53: 1925-34. PMID 24606314 DOI: 10.1021/Bi5001867  0.362
2014 Yin Z, Whittell LR, Wang Y, Jergic S, Liu M, Harry EJ, Dixon NE, Beck JL, Kelso MJ, Oakley AJ. Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. Journal of Medicinal Chemistry. 57: 2799-806. PMID 24592885 DOI: 10.1021/Jm500122R  0.467
2014 Shishmarev D, Wang Y, Mason CE, Su XC, Oakley AJ, Graham B, Huber T, Dixon NE, Otting G. Intramolecular binding mode of the C-terminus of Escherichia coli single-stranded DNA binding protein determined by nuclear magnetic resonance spectroscopy. Nucleic Acids Research. 42: 2750-7. PMID 24288378 DOI: 10.1093/Nar/Gkt1238  0.368
2014 Berghuis BA, Dulin D, Cross B, Dixon NE, Dekker NH. Roadblocks on the E.Coli Genome: The Workings of a Molecular Mouse Trap at the Single-Molecule Level Biophysical Journal. 106: 230a. DOI: 10.1016/J.Bpj.2013.11.1344  0.548
2013 Johansson E, Dixon N. Replicative DNA polymerases. Cold Spring Harbor Perspectives in Biology. 5. PMID 23732474 DOI: 10.1101/Cshperspect.A012799  0.581
2013 Ozawa K, Horan NP, Robinson A, Yagi H, Hill FR, Jergic S, Xu ZQ, Loscha KV, Li N, Tehei M, Oakley AJ, Otting G, Huber T, Dixon NE. Proofreading exonuclease on a tether: the complex between the E. coli DNA polymerase III subunits α, epsilon, θ and β reveals a highly flexible arrangement of the proofreading domain. Nucleic Acids Research. 41: 5354-67. PMID 23580545 DOI: 10.1093/Nar/Gkt162  0.453
2013 Jergic S, Horan NP, Elshenawy MM, Mason CE, Urathamakul T, Ozawa K, Robinson A, Goudsmits JM, Wang Y, Pan X, Beck JL, van Oijen AM, Huber T, Hamdan SM, Dixon NE. A direct proofreader-clamp interaction stabilizes the Pol III replicase in the polymerization mode. The Embo Journal. 32: 1322-33. PMID 23435564 DOI: 10.1038/Emboj.2012.347  0.718
2013 Mason CE, Jergic S, Lo AT, Wang Y, Dixon NE, Beck JL. Escherichia coli single-stranded DNA-binding protein: nanoESI-MS studies of salt-modulated subunit exchange and DNA binding transactions. Journal of the American Society For Mass Spectrometry. 24: 274-85. PMID 23283730 DOI: 10.1007/S13361-012-0552-2  0.543
2012 Mansfield RE, Dixon NE. Priming the engine of DNA synthesis. Structure (London, England : 1993). 20: 1447-8. PMID 22958638 DOI: 10.1016/J.Str.2012.08.013  0.375
2012 Ozawa K, Loscha KV, Kuppan KV, Loh CT, Dixon NE, Otting G. High-yield cell-free protein synthesis for site-specific incorporation of unnatural amino acids at two sites. Biochemical and Biophysical Research Communications. 418: 652-6. PMID 22293204 DOI: 10.1016/J.Bbrc.2012.01.069  0.305
2012 Robinson A, Causer RJ, Dixon NE. Architecture and conservation of the bacterial DNA replication machinery, an underexploited drug target. Current Drug Targets. 13: 352-72. PMID 22206257 DOI: 10.2174/138945012799424598  0.418
2011 Wijffels G, Johnson WM, Oakley AJ, Turner K, Epa VC, Briscoe SJ, Polley M, Liepa AJ, Hofmann A, Buchardt J, Christensen C, Prosselkov P, Dalrymple BP, Alewood PF, Jennings PA, ... Dixon NE, et al. Binding inhibitors of the bacterial sliding clamp by design. Journal of Medicinal Chemistry. 54: 4831-8. PMID 21604761 DOI: 10.1021/Jm2004333  0.37
2011 Tanner NA, Tolun G, Loparo JJ, Jergic S, Griffith JD, Dixon NE, van Oijen AM. E. coli DNA replication in the absence of free β clamps. The Embo Journal. 30: 1830-40. PMID 21441898 DOI: 10.1038/Emboj.2011.84  0.814
2011 Urathamakul T, Williams NK, Dixon NE, Beck JL. EX1 hydrogen-deuterium exchange in an all-helical protein and its cyclized derivative at neutral pH International Journal of Mass Spectrometry. 302: 149-156. DOI: 10.1016/J.Ijms.2010.09.011  0.31
2010 Robinson A, Brzoska AJ, Turner KM, Withers R, Harry EJ, Lewis PJ, Dixon NE. Essential biological processes of an emerging pathogen: DNA replication, transcription, and cell division in Acinetobacter spp. Microbiology and Molecular Biology Reviews : Mmbr. 74: 273-97. PMID 20508250 DOI: 10.1128/Mmbr.00048-09  0.34
2010 Morin I, Dixon NE, Schaeffer PM. Ultrasensitive detection of antibodies using a new Tus-Ter-lock immunoPCR system. Molecular Biosystems. 6: 1173-5. PMID 20464017 DOI: 10.1039/C002163F  0.327
2010 Athanasopoulos V, Barker A, Yu D, Tan AH, Srivastava M, Contreras N, Wang J, Lam KP, Brown SH, Goodnow CC, Dixon NE, Leedman PJ, Saint R, Vinuesa CG. The ROQUIN family of proteins localizes to stress granules via the ROQ domain and binds target mRNAs. The Febs Journal. 277: 2109-27. PMID 20412057 DOI: 10.1111/J.1742-4658.2010.07628.X  0.31
2010 Park AY, Jergic S, Politis A, Ruotolo BT, Hirshberg D, Jessop LL, Beck JL, Barsky D, O'Donnell M, Dixon NE, Robinson CV. A single subunit directs the assembly of the Escherichia coli DNA sliding clamp loader. Structure (London, England : 1993). 18: 285-92. PMID 20223211 DOI: 10.1016/J.Str.2010.01.009  0.602
2010 Tanaka S, Kawata Y, Otting G, Dixon NE, Matsuzaki K, Hoshino M. Chaperonin-encapsulation of proteins for NMR. Biochimica Et Biophysica Acta. 1804: 866-71. PMID 20045085 DOI: 10.1016/J.Bbapap.2009.12.016  0.345
2009 Dixon NE. DNA replication: prime-time looping. Nature. 462: 854-5. PMID 20016583 DOI: 10.1038/462854A  0.549
2009 Xun Y, Tremouilhac P, Carraher C, Gelhaus C, Ozawa K, Otting G, Dixon NE, Leippe M, Grötzinger J, Dingley AJ, Kralicek AV. Cell-free synthesis and combinatorial selective 15N-labeling of the cytotoxic protein amoebapore A from Entamoeba histolytica. Protein Expression and Purification. 68: 22-7. PMID 19573603 DOI: 10.1016/J.Pep.2009.06.017  0.317
2009 Dahdah DB, Morin I, Moreau MJ, Dixon NE, Schaeffer PM. Site-specific covalent attachment of DNA to proteins using a photoactivatable Tus-Ter complex. Chemical Communications (Cambridge, England). 3050-2. PMID 19462083 DOI: 10.1039/B900905A  0.527
2009 Loscha KV, Jaudzems K, Ioannou C, Su XC, Hill FR, Otting G, Dixon NE, Liepinsh E. A novel zinc-binding fold in the helicase interaction domain of the Bacillus subtilis DnaI helicase loader. Nucleic Acids Research. 37: 2395-404. PMID 19255093 DOI: 10.1093/Nar/Gkp092  0.391
2009 Tanner NA, Loparo JJ, Hamdan SM, Jergic S, Dixon NE, van Oijen AM. Real-time single-molecule observation of rolling-circle DNA replication. Nucleic Acids Research. 37: e27. PMID 19155275 DOI: 10.1093/Nar/Gkp006  0.712
2009 Schaeffer PM, Dixon NE. Synthesis and applications of covalent protein-DNA conjugates Australian Journal of Chemistry. 62: 1328-1332. DOI: 10.1071/Ch09164  0.491
2009 Barsky D, Park A, Hirschberg D, Ruotolo BT, Jergic S, Dixon NE, O'Donnell M, Robinson CV. Ion Mobility-Mass Spectrometry Measurements Combined with Molecular Modeling Yields the Architecture of DNA Polymerase Complexes Biophysical Journal. 96: 209a. DOI: 10.1016/J.Bpj.2008.12.1854  0.551
2008 Tanner NA, Hamdan SM, Jergic S, Loscha KV, Schaeffer PM, Dixon NE, van Oijen AM. Single-molecule studies of fork dynamics in Escherichia coli DNA replication. Nature Structural & Molecular Biology. 15: 998. PMID 18769472 DOI: 10.1038/nsmb0908-998a  0.675
2008 Ozawa K, Jergic S, Park AY, Dixon NE, Otting G. The proofreading exonuclease subunit epsilon of Escherichia coli DNA polymerase III is tethered to the polymerase subunit alpha via a flexible linker. Nucleic Acids Research. 36: 5074-82. PMID 18663010 DOI: 10.1093/Nar/Gkn489  0.409
2008 Apponyi MA, Ozawa K, Dixon NE, Otting G. Cell-free protein synthesis for analysis by NMR spectroscopy. Methods in Molecular Biology (Clifton, N.J.). 426: 257-68. PMID 18542869 DOI: 10.1007/978-1-60327-058-8_16  0.324
2008 Tanner NA, Hamdan SM, Jergic S, Loscha KV, Schaeffer PM, Dixon NE, van Oijen AM. Single-molecule studies of fork dynamics in Escherichia coli DNA replication. Nature Structural & Molecular Biology. 15: 170-6. PMID 18223657 DOI: 10.1038/Nsmb.1381  0.717
2008 Young Park A, Elvin CM, Hamdan SM, Wood RJ, Liyou NE, Hamwood TE, Jennings PA, Dixon NE. Hydrolysis of the 5'-p-nitrophenyl ester of TMP by oligoribonucleases (ORN) from Escherichia coli, Mycobacterium smegmatis, and human. Protein Expression and Purification. 57: 180-7. PMID 18023590 DOI: 10.1016/J.Pep.2007.10.005  0.304
2007 John M, Schmitz C, Park AY, Dixon NE, Huber T, Otting G. Sequence-specific and stereospecific assignment of methyl groups using paramagnetic lanthanides. Journal of the American Chemical Society. 129: 13749-57. PMID 17929923 DOI: 10.1021/Ja0744753  0.339
2007 Su XC, Jergic S, Keniry MA, Dixon NE, Otting G. Solution structure of Domains IVa and V of the tau subunit of Escherichia coli DNA polymerase III and interaction with the alpha subunit. Nucleic Acids Research. 35: 2825-32. PMID 17452361 DOI: 10.1093/Nar/Gkm080  0.363
2007 Su XC, Jergic S, Ozawa K, Burns ND, Dixon NE, Otting G. Measurement of dissociation constants of high-molecular weight protein-protein complexes by transferred 15N-relaxation. Journal of Biomolecular Nmr. 38: 65-72. PMID 17390106 DOI: 10.1007/S10858-007-9147-9  0.392
2007 Wu PS, Ozawa K, Lim SP, Vasudevan SG, Dixon NE, Otting G. Cell-free transcription/translation from PCR-amplified DNA for high-throughput NMR studies. Angewandte Chemie (International Ed. in English). 46: 3356-8. PMID 17378006 DOI: 10.1002/Anie.200605237  0.442
2007 Jergic S, Ozawa K, Williams NK, Su XC, Scott DD, Hamdan SM, Crowther JA, Otting G, Dixon NE. The unstructured C-terminus of the tau subunit of Escherichia coli DNA polymerase III holoenzyme is the site of interaction with the alpha subunit. Nucleic Acids Research. 35: 2813-24. PMID 17355988 DOI: 10.1093/Nar/Gkm079  0.308
2007 Watt SJ, Urathamakul T, Schaeffer PM, Williams NK, Sheil MM, Dixon NE, Beck JL. Multiple oligomeric forms of Escherichia coli DnaB helicase revealed by electrospray ionisation mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 21: 132-40. PMID 17154355 DOI: 10.1002/Rcm.2818  0.457
2007 John M, Headlam MJ, Dixon NE, Otting G. Assignment of paramagnetic (15)N-HSQC spectra by heteronuclear exchange spectroscopy. Journal of Biomolecular Nmr. 37: 43-51. PMID 17096205 DOI: 10.1007/S10858-006-9098-6  0.332
2007 Wu PSC, Ozawa K, Lim SP, Vasudevan SG, Dixon NE, Otting G. Zellfreie Transkription/Translation von PCR‐amplifizierter DNA für NMR‐Studien mit hohem Durchsatz Angewandte Chemie. 119: 3420-3422. DOI: 10.1002/Ange.200605237  0.528
2006 Su XC, Schaeffer PM, Loscha KV, Gan PH, Dixon NE, Otting G. Monomeric solution structure of the helicase-binding domain of Escherichia coli DnaG primase. The Febs Journal. 273: 4997-5009. PMID 17010164 DOI: 10.1111/J.1742-4658.2006.05495.X  0.364
2006 Ioannou C, Schaeffer PM, Dixon NE, Soultanas P. Helicase binding to DnaI exposes a cryptic DNA-binding site during helicase loading in Bacillus subtilis. Nucleic Acids Research. 34: 5247-58. PMID 17003052 DOI: 10.1093/Nar/Gkl690  0.459
2006 John M, Pintacuda G, Park AY, Dixon NE, Otting G. Structure determination of protein-ligand complexes by transferred paramagnetic shifts. Journal of the American Chemical Society. 128: 12910-6. PMID 17002387 DOI: 10.1021/Ja063584Z  0.315
2006 Ozawa K, Wu PS, Dixon NE, Otting G. N-Labelled proteins by cell-free protein synthesis. Strategies for high-throughput NMR studies of proteins and protein-ligand complexes. The Febs Journal. 273: 4154-9. PMID 16930129 DOI: 10.1111/J.1742-4658.2006.05433.X  0.318
2006 Su XC, Huber T, Dixon NE, Otting G. Site-specific labelling of proteins with a rigid lanthanide-binding tag. Chembiochem : a European Journal of Chemical Biology. 7: 1599-604. PMID 16927254 DOI: 10.1002/Cbic.200600142  0.398
2006 Mulcair MD, Schaeffer PM, Oakley AJ, Cross HF, Neylon C, Hill TM, Dixon NE. A molecular mousetrap determines polarity of termination of DNA replication in E. coli. Cell. 125: 1309-19. PMID 16814717 DOI: 10.1016/J.Cell.2006.04.040  0.477
2006 Schmitz C, John M, Park AY, Dixon NE, Otting G, Pintacuda G, Huber T. Efficient chi-tensor determination and NH assignment of paramagnetic proteins. Journal of Biomolecular Nmr. 35: 79-87. PMID 16767502 DOI: 10.1007/S10858-006-9002-4  0.36
2006 Keniry MA, Park AY, Owen EA, Hamdan SM, Pintacuda G, Otting G, Dixon NE. Structure of the theta subunit of Escherichia coli DNA polymerase III in complex with the epsilon subunit. Journal of Bacteriology. 188: 4464-73. PMID 16740953 DOI: 10.1128/Jb.01992-05  0.386
2006 Beck JL, Urathamakul T, Watt SJ, Sheil MM, Schaeffer PM, Dixon NE. Proteomic dissection of DNA polymerization. Expert Review of Proteomics. 3: 197-211. PMID 16608433 DOI: 10.1586/14789450.3.2.197  0.528
2006 Pintacuda G, Park AY, Keniry MA, Dixon NE, Otting G. Lanthanide labeling offers fast NMR approach to 3D structure determinations of protein-protein complexes. Journal of the American Chemical Society. 128: 3696-702. PMID 16536542 DOI: 10.1021/Ja057008Z  0.361
2006 Wu PS, Ozawa K, Jergic S, Su XC, Dixon NE, Otting G. Amino-acid type identification in 15N-HSQC spectra by combinatorial selective 15N-labelling. Journal of Biomolecular Nmr. 34: 13-21. PMID 16505960 DOI: 10.1007/S10858-005-5021-9  0.323
2006 Graham SC, Lilley PE, Lee M, Schaeffer PM, Kralicek AV, Dixon NE, Guss JM. Kinetic and crystallographic analysis of mutant Escherichia coli aminopeptidase P: Insights into substrate recognition and the mechanism of catalysis Biochemistry. 45: 964-975. PMID 16411772 DOI: 10.1021/Bi0518904  0.312
2005 Elvin CM, Carr AG, Huson MG, Maxwell JM, Pearson RD, Vuocolo T, Liyou NE, Wong DC, Merritt DJ, Dixon NE. Synthesis and properties of crosslinked recombinant pro-resilin. Nature. 437: 999-1002. PMID 16222249 DOI: 10.1038/Nature04085  0.317
2005 Ozawa K, Dixon NE, Otting G. Cell-free synthesis of 15N-labeled proteins for NMR studies. Iubmb Life. 57: 615-22. PMID 16203680 DOI: 10.1080/15216540500217859  0.325
2005 Neylon C, Kralicek AV, Hill TM, Dixon NE. Replication termination in Escherichia coli: structure and antihelicase activity of the Tus-Ter complex. Microbiology and Molecular Biology Reviews : Mmbr. 69: 501-26. PMID 16148308 DOI: 10.1128/Mmbr.69.3.501-526.2005  0.504
2005 Schaeffer PM, Headlam MJ, Dixon NE. Protein--protein interactions in the eubacterial replisome. Iubmb Life. 57: 5-12. PMID 16036556 DOI: 10.1080/15216540500058956  0.499
2005 Wijffels G, Dalrymple B, Kongsuwan K, Dixon NE. Conservation of eubacterial replicases. Iubmb Life. 57: 413-9. PMID 16012050 DOI: 10.1080/15216540500138246  0.44
2005 Ozawa K, Headlam MJ, Mouradov D, Watt SJ, Beck JL, Rodgers KJ, Dean RT, Huber T, Otting G, Dixon NE. Translational incorporation of L-3,4-dihydroxyphenylalanine into proteins. The Febs Journal. 272: 3162-71. PMID 15955073 DOI: 10.1111/J.1742-4658.2005.04735.X  0.315
2005 Robinson A, Wu PS, Harrop SJ, Schaeffer PM, Dosztányi Z, Gillings MR, Holmes AJ, Nevalainen KM, Stokes HW, Otting G, Dixon NE, Curmi PM, Mabbutt BC. Integron-associated mobile gene cassettes code for folded proteins: the structure of Bal32a, a new member of the adaptable alpha+beta barrel family. Journal of Molecular Biology. 346: 1229-41. PMID 15713477 DOI: 10.1016/J.Jmb.2004.12.035  0.329
2005 Williams NK, Liepinsh E, Watt SJ, Prosselkov P, Matthews JM, Attard P, Beck JL, Dixon NE, Otting G. Stabilization of native protein fold by intein-mediated covalent cyclization. Journal of Molecular Biology. 346: 1095-108. PMID 15701520 DOI: 10.1016/J.Jmb.2004.12.037  0.337
2005 Duggin IG, Matthews JM, Dixon NE, Wake RG, Mackay JP. A complex mechanism determines polarity of DNA replication fork arrest by the replication terminator complex of Bacillus subtilis Journal of Biological Chemistry. 280: 13105-13113. PMID 15657033 DOI: 10.1074/Jbc.M414187200  0.394
2005 Oakley AJ, Loscha KV, Schaeffer PM, Liepinsh E, Pintacuda G, Wilce MC, Otting G, Dixon NE. Crystal and solution structures of the helicase-binding domain of Escherichia coli primase. The Journal of Biological Chemistry. 280: 11495-504. PMID 15649896 DOI: 10.1074/Jbc.M412645200  0.413
2004 Ozawa K, Headlam MJ, Schaeffer PM, Henderson BR, Dixon NE, Otting G. Optimization of an Escherichia coli system for cell-free synthesis of selectively N-labelled proteins for rapid analysis by NMR spectroscopy. European Journal of Biochemistry / Febs. 271: 4084-93. PMID 15479237 DOI: 10.1111/J.1432-1033.2004.04346.X  0.338
2004 Gupta R, Hamdan SM, Dixon NE, Sheil MM, Beck JL. Application of electrospray ionization mass spectrometry to study the hydrophobic interaction between the epsilon and theta subunits of DNA polymerase III. Protein Science : a Publication of the Protein Society. 13: 2878-87. PMID 15459336 DOI: 10.1110/Ps.04889604  0.34
2004 Wijffels G, Dalrymple BP, Prosselkov P, Kongsuwan K, Epa VC, Lilley PE, Jergic S, Buchardt J, Brown SE, Alewood PF, Jennings PA, Dixon NE. Inhibition of protein interactions with the beta 2 sliding clamp of Escherichia coli DNA polymerase III by peptides from beta 2-binding proteins. Biochemistry. 43: 5661-71. PMID 15134440 DOI: 10.1021/Bi036229J  0.384
2004 Pintacuda G, Keniry MA, Huber T, Park AY, Dixon NE, Otting G. Fast structure-based assignment of 15N HSQC spectra of selectively 15N-labeled paramagnetic proteins. Journal of the American Chemical Society. 126: 2963-70. PMID 14995214 DOI: 10.1021/Ja039339M  0.341
2004 Loscha K, Oakley AJ, Bancia B, Schaeffer PM, Prosselkov P, Otting G, Wilce MC, Dixon NE. Expression, purification, crystallization, and NMR studies of the helicase interaction domain of Escherichia coli DnaG primase. Protein Expression and Purification. 33: 304-10. PMID 14711519 DOI: 10.1016/J.Pep.2003.10.001  0.347
2003 Oakley AJ, Prosselkov P, Wijffels G, Beck JL, Wilce MC, Dixon NE. Flexibility revealed by the 1.85 A crystal structure of the beta sliding-clamp subunit of Escherichia coli DNA polymerase III. Acta Crystallographica. Section D, Biological Crystallography. 59: 1192-9. PMID 12832762 DOI: 10.1107/S0907444903009958  0.407
2002 Guignard L, Ozawa K, Pursglove SE, Otting G, Dixon NE. NMR analysis of in vitro-synthesized proteins without purification: a high-throughput approach Febs Letters. 524: 159-162. PMID 12135760 DOI: 10.1016/S0014-5793(02)03048-X  0.322
2002 Hamdan S, Bulloch EM, Thompson PR, Beck JL, Yang JY, Crowther JA, Lilley PE, Carr PD, Ollis DL, Brown SE, Dixon NE. Hydrolysis of the 5'-p-nitrophenyl ester of TMP by the proofreading exonuclease (epsilon) subunit of Escherichia coli DNA polymerase III. Biochemistry. 41: 5266-75. PMID 11955076 DOI: 10.1021/Bi0159480  0.386
2002 Hamdan S, Carr PD, Brown SE, Ollis D, Dixon N. Structural Basis for Proofreading during Replication of the Escherichia coli Chromosome Structure. 10: 535-546. PMID 11937058 DOI: 10.1016/S0969-2126(02)00738-4  0.499
2002 Kapur A, Beck JL, Brown SE, Dixon NE, Sheil MM. Use of electrospray ionization mass spectrometry to study binding interactions between a replication terminator protein and DNA. Protein Science : a Publication of the Protein Society. 11: 147-57. PMID 11742131 DOI: 10.1110/Ps.27702  0.503
2002 Williams NK, Prosselkov P, Liepinsh E, Line I, Sharipo A, Littler DR, Curmi PM, Otting G, Dixon NE. In vivo protein cyclization promoted by a circularly permuted Synechocystis sp. PCC6803 DnaB mini-intein. The Journal of Biological Chemistry. 277: 7790-8. PMID 11742000 DOI: 10.1074/Jbc.M110303200  0.345
2001 Dalrymple BP, Kongsuwan K, Wijffels G, Dixon NE, Jennings PA. A universal protein-protein interaction motif in the eubacterial DNA replication and repair systems. Proceedings of the National Academy of Sciences of the United States of America. 98: 11627-32. PMID 11573000 DOI: 10.1073/Pnas.191384398  0.539
2001 Levina A, Lay PA, Dixon NE. Disproportionation of a model chromium(V) complex causes extensive chromium(III)-DNA binding in vitro. Chemical Research in Toxicology. 14: 946-50. PMID 11511167 DOI: 10.1021/Tx010077G  0.361
2001 Pattison DI, Davies MJ, Levina A, Dixon NE, Lay PA. Chromium(VI) reduction by catechol(amine)s results in DNA cleavage in vitro: relevance to chromium genotoxicity. Chemical Research in Toxicology. 14: 500-10. PMID 11368547 DOI: 10.1021/Tx000229S  0.377
2001 Bárcena M, Ruiz T, Donate LE, Brown SE, Dixon NE, Radermacher M, Carazo JM. The DnaB.DnaC complex: a structure based on dimers assembled around an occluded channel. The Embo Journal. 20: 1462-8. PMID 11250911 DOI: 10.1093/Emboj/20.6.1462  0.494
2001 Levina A, Lay PA, Dixon NE. Disproportionation and nuclease activity of bis[2-ethyl-2-hydroxybutanoato(2-)]oxochromate(V) in neutral aqueous solutions. Inorganic Chemistry. 39: 385-95. PMID 11229553 DOI: 10.1021/Ic990729C  0.348
2000 Hamdan S, Brown SE, Thompson P, Yang JY, Carr PD, Ollis D, Otting G, Dixon N. Preliminary X-Ray Crystallographic and NMR Studies on the Exonuclease Domain of the ϵ Subunit of Escherichia coli DNA Polymerase III Journal of Structural Biology. 131: 164-169. PMID 11042088 DOI: 10.1006/Jsbi.2000.4291  0.396
2000 Donate LE, Llorca O, Bárcena M, Brown SE, Dixon NE, Carazo JM. pH-controlled quaternary states of hexameric DnaB helicase. Journal of Molecular Biology. 303: 383-93. PMID 11031115 DOI: 10.1006/Jmbi.2000.4132  0.418
2000 Neylon C, Brown SE, Kralicek AV, Miles CS, Love CA, Dixon NE. Interaction of the Escherichia coli replication terminator protein (Tus) with DNA: A model derived from DNA-binding studies of mutant proteins by surface plasmon resonance Biochemistry. 39: 11989-11999. PMID 11009613 DOI: 10.1021/Bi001174W  0.488
2000 Keniry MA, Berthon HA, Yang JY, Miles CS, Dixon NE. NMR solution structure of the θ subunit of DNA polymerase III from Escherichia coli Protein Science. 9: 721-733. PMID 10794414 DOI: 10.1110/Ps.9.4.721  0.408
2000 Dillon CT, Lay PA, Bonin AM, Dixon NE, Sulfab Y. DNA Interactions and Bacterial Mutagenicity of Some Chromium(III) Imine Complexes and their Chromium(V) Analogues. Evidence for Chromium(V) Intermediates in the Genotoxicity of Chromium(III) Australian Journal of Chemistry. 53: 411. DOI: 10.1071/Ch00006  0.457
2000 Dixon NE, Hamdan S, Brown SE, Keniry MA, Carr PD, Ollis DL, Otting G. Studies of the Structures of Core Subunits of Escherichia coli DNA Polymerase III Holoenzyme Biochemical Society Transactions. 28. DOI: 10.1042/Bst028A416C  0.507
2000 Moghaddas S, Hendry P, Geue RJ, Qin C, Bygott AMT, Sargeson AM, Dixon NE. Interaction of substituted cobalt(III) cage complexes with DNA Journal of the Chemical Society, Dalton Transactions. 2085-2089. DOI: 10.1039/B003008M  0.519
1999 Weigelt J, Brown SE, Miles CS, Dixon NE, Otting G. NMR structure of the N-terminal domain of E. coli DnaB helicase: Implications for structure rearrangements in the helicase hexamer Structure. 7: 681-690. PMID 10404597 DOI: 10.1016/S0969-2126(99)80089-6  0.318
1999 Levina A, Barr-David G, Codd R, Lay PA, Dixon NE, Hammershøi A, Hendry P. In vitro plasmid DNA cleavage by chromium(V) and -(IV) 2-hydroxycarboxylato complexes. Chemical Research in Toxicology. 12: 371-81. PMID 10207127 DOI: 10.1021/Tx980229G  0.446
1998 San Martin C, Radermacher M, Wolpensinger B, Engel A, Miles CS, Dixon NE, Carazo JM. Three-dimensional reconstructions from cryoelectron microscopy images reveal an intimate complex between helicase DnaB and its loading partner DnaC Structure. 6: 501-509. PMID 9562559 DOI: 10.1016/S0969-2126(98)00051-3  0.47
1998 Wilce MCJ, Bond CS, Dixon NE, Freeman HC, Guss JM, Lilley PE, Wilce JA. Structure and mechanism of a proline-specific aminopeptidase from Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 95: 3472-3477. PMID 9520390 DOI: 10.1073/Pnas.95.7.3472  0.357
1997 Edwards KJ, Ollis DL, Dixon NE. Crystal structure of cytoplasmic Escherichia coli peptidyl-prolyl isomerase: Evidence for decreased mobility of loops upon complexation Journal of Molecular Biology. 271: 258-265. PMID 9268657 DOI: 10.1006/Jmbi.1997.1151  0.303
1997 Miles CS, Weigelt J, Stamford NPJ, Dammerova N, Otting G, Dixon NE. Precise limits of the N-terminal domain of DnaB helicase determined by NMR spectroscopy Biochemical and Biophysical Research Communications. 231: 126-130. PMID 9070233 DOI: 10.1006/Bbrc.1997.6059  0.335
1996 Carr PD, Cheah E, Suffolk PM, Vasudevan SG, Dixon NE, Ollis DL. X-ray structure of the signal transduction protein from Escherichia coli at 1.9 A. Acta Crystallographica Section D-Biological Crystallography. 52: 93-104. PMID 15299730 DOI: 10.1107/S0907444995007293  0.337
1996 Love CA, Lilley PE, Dixon NE. Stable high-copy-number bacteriophage lambda promoter vectors for overproduction of proteins in Escherichia coli Gene. 176: 49-53. PMID 8918231 DOI: 10.1016/0378-1119(96)00208-9  0.325
1996 Dixon NE, Geue RJ, Lambert JN, Moghaddas S, Pearce DA, Sargeson AM. DNA hydrolysis by stable metal complexes Chemical Communications. 1287-1288. DOI: 10.1039/Cc9960001287  0.438
1995 Martin MCS, Stamford NPJ, Dammerova N, Dixon NE, Carazo JM. A structural model for the Escherichia coli DnaB helicase based on electron microscopy data. Journal of Structural Biology. 114: 167-176. PMID 7662485 DOI: 10.1006/Jsbi.1995.1016  0.556
1995 Thorn JM, Barton JD, Dixon NE, Ollis DL, Edwards KJ. Crystal structure of Escherichia coli QOR quinone oxidoreductase complexed with NADPH. Journal of Molecular Biology. 249: 785-99. PMID 7602590 DOI: 10.1006/Jmbi.1995.0337  0.323
1995 Hendry P, Moghaddas S, Dixon NE, Bygott A, Gene RJ, Qin C, Sargeson AM. The interaction of cobalt(III)-SAR cage complexes with DNA Journal of Inorganic Biochemistry. 59: 164. DOI: 10.1016/0162-0134(95)97272-R  0.476
1994 Vasudevan SG, Gedye C, Dixon NE, Cheah E, Carr PD, Suffolk PM, Jeffrey PD, Ollis DL. Escherichia coli PII protein: purification, crystallization and oligomeric structure. Febs Letters. 337: 255-258. PMID 8293810 DOI: 10.1016/0014-5793(94)80203-3  0.314
1994 Thorn JM, Carr PD, Chase JW, Dixon NE, Ollis DL. Crystallization and low temperature diffraction studies of the DNA binding domain of the single-stranded DNA binding protein from Escherichia coli. Journal of Molecular Biology. 240: 396-9. PMID 8035462 DOI: 10.1006/Jmbi.1994.1453  0.426
1994 Cheah E, Carr PD, Suffolk PM, Vasudevan SG, Dixon NE, Ollis DL. Structure of the Escherichia coli signal transducing protein PII Structure. 2: 981-990. PMID 7866749 DOI: 10.1016/S0969-2126(94)00100-6  0.304
1993 Dillon CT, Lay PA, Bonin AM, Dixon NE, Collins TJ, Kostka KL. In vitro DNA damage and mutations induced by a macrocyclic tetraamide chromium(V) complex: implications for the role of Cr(V) peptide complexes in chromium-induced cancers. Carcinogenesis. 14: 1875-80. PMID 8403213 DOI: 10.1093/Carcin/14.9.1875  0.36
1993 Allen GC, Dixon NE, Kornberg A. Strand switching of a replicative DNA helicase promoted by the E. coli primosome Cell. 74: 713-722. PMID 8395352 DOI: 10.1016/0092-8674(93)90518-U  0.646
1993 Hartman DJ, Surin BP, Dixon NE, Hoogenraad NJ, Hoj PB. Substoichiometric amounts of the molecular chaperones GroEL and GroES prevent thermal denaturation and aggregation of mammalian mitochondrial malate dehydrogenase in vitro. Proceedings of the National Academy of Sciences of the United States of America. 90: 2276-2280. PMID 8096339 DOI: 10.1073/Pnas.90.6.2276  0.318
1992 Farrell RP, Judd RJ, Lay PA, Dixon NE, Baker RS, Bonin AM. Chromium(V)-induced cleavage of DNA: are chromium(V) complexes the active carcinogens in chromium(VI)-induced cancers? Chemical Research in Toxicology. 2: 227-9. PMID 2519778 DOI: 10.1021/Tx00010A002  0.369
1992 Stamford NPJ, Lilley PE, Dixon NE. Enriched sources of Escherichia coli replication proteins: The dnaG primase is a zinc metalloprotein Biochimica Et Biophysica Acta. 1132: 17-25. PMID 1511009 DOI: 10.1016/0167-4781(92)90047-4  0.472
1992 Barr-David G, Hambley TW, Irwin JA, Judd RJ, Lay PA, Martin BD, Bramley R, Dixon NE, Hendry P. Suppression by vanadium(IV) of chromium(V)-mediated DNA cleavage and chromium(VI/V)-induced mutagenesis. Synthesis and crystal structure of the vanadium(IV) complex (NH4)[V(O){HOC(Et)2COO}{OC(Et)2COO}] Inorganic Chemistry. 31: 4906-4908. DOI: 10.1021/Ic00050A002  0.325
1991 Vasudevan SG, Armarego WLF, Shawl DC, Lilley PE, Dixon NE, Poole RK. Isolation and nucleotide sequence of the hmp gene that encodes a haemoglobin-like protein in Escherichia coli K-12 Molecular Genetics and Genomics. 226: 49-58. PMID 2034230 DOI: 10.1007/Bf00273586  0.357
1990 Elvin CM, Thompson PR, Argall ME, Hendry P, Stamford NP, Lilley PE, Dixon NE. Modified bacteriophage lambda promoter vectors for overproduction of proteins in Escherichia coli. Gene. 87: 123-6. PMID 2139621 DOI: 10.1016/0378-1119(90)90503-J  0.366
1989 Armarego WLF, Cotton RGH, Dahl H-M, Dixon NE. High-level expression of human dihydropteridine reductase (EC 1.6.99.7), without N-terminal amino acid protection, in Escherichia coli Biochemical Journal. 261: 265-268. PMID 2673215 DOI: 10.1042/Bj2610265  0.301
1986 Surin BP, Dixon NE, Rosenberg H. Purification of the phoU protein, a negative regulator of the pho regulon of Escherichia coli K-12. Journal of Bacteriology. 168: 631-635. PMID 3536855 DOI: 10.1128/Jb.168.2.631-635.1986  0.307
1986 Elvin CM, Dixon NE, Rosenberg H. Molecular cloning of the phosphate (inorganic) transport (pit) gene of Escherichia coli K12. Identification of the pit+ gene product and physical mapping of the pit-gor region of the chromosome. Molecular Genetics and Genomics. 204: 477-484. PMID 3020381 DOI: 10.1007/Bf00331028  0.307
1984 Dixon NE, Kornberg A. Protein HU in the enzymatic replication of the chromosomal origin of Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 81: 424-428. PMID 6364143 DOI: 10.1073/Pnas.81.2.424  0.623
1983 Stayton MM, Bertsch L, Biswas S, Burgers P, Dixon N, Flynn JE, Fuller R, Kaguni J, Kobori J, Kodaira M, Low R, Kornberg A. Enzymatic recognition of DNA replication origins. Cold Spring Harbor Symposia On Quantitative Biology. 47: 693-700. PMID 6345074 DOI: 10.1101/Sqb.1983.047.01.080  0.767
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