☰

Deniz Dalkara, Ph.D. - Publications

Affiliations: 
Ophthalmology Institut de la Vision, Paris 
Area:
Gene therapies, animal models for neurodegenerative diseases
Website:
http://www.institut-vision.org/index.php?option=com_content&id=326:equipe-de-deniz-dalkara&Itemid=15&lang=en
Tree Info Grants Similar researchers Related pubs Distance to... Nearest Nobel PubMed Report error

88/106 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Khabou H, Orendorff E, Trapani F, Rucli M, Desrosiers M, Yger P, Dalkara D, Marre O. Optogenetic targeting of AII amacrine cells restores retinal computations performed by the inner retina. Molecular Therapy. Methods & Clinical Development. 31: 101107. PMID 37868206 DOI: 10.1016/j.omtm.2023.09.003  0.863
2023 Ail D, Nava D, Hwang IP, Brazhnikova E, Nouvel-Jaillard C, Dentel A, Joffrois C, Rousseau L, Dégardin J, Bertin S, Sahel JA, Goureau O, Picaud S, Dalkara D. Inducible nonhuman primate models of retinal degeneration for testing end-stage therapies. Science Advances. 9: eadg8163. PMID 37531424 DOI: 10.1126/sciadv.adg8163  0.428
2023 Ail D, Dalkara D. Preexisting Neutralizing Antibodies against Different Adeno-Associated Virus Serotypes in Humans and Large Animal Models for Gene Therapy. Advances in Experimental Medicine and Biology. 1415: 117-123. PMID 37440023 DOI: 10.1007/978-3-031-27681-1_18  0.346
2023 Ail D, Malki H, Zin EA, Dalkara D. Adeno-Associated Virus (AAV) - Based Gene Therapies for Retinal Diseases: Where are We? The Application of Clinical Genetics. 16: 111-130. PMID 37274131 DOI: 10.2147/TACG.S383453  0.524
2023 Zin EA, Ozturk BE, Dalkara D, Byrne LC. Developing New Vectors for Retinal Gene Therapy. Cold Spring Harbor Perspectives in Medicine. PMID 36987583 DOI: 10.1101/cshperspect.a041291  0.775
2022 Ren D, Fisson S, Dalkara D, Ail D. Immune Responses to Gene Editing by Viral and Non-Viral Delivery Vectors Used in Retinal Gene Therapy. Pharmaceutics. 14. PMID 36145721 DOI: 10.3390/pharmaceutics14091973  0.393
2022 Leroy BP, Fischer MD, Flannery JG, MacLaren RE, Dalkara D, Scholl HPN, Chung DC, Spera C, Viriato D, Banhazi J. Gene therapy for inherited retinal disease: long-term durability of effect. Ophthalmic Research. PMID 36103843 DOI: 10.1159/000526317  0.672
2022 Spampinato GLB, Ronzitti E, Zampini V, Ferrari U, Trapani F, Khabou H, Agraval A, Dalkara D, Picaud S, Papagiakoumou E, Marre O, Emiliani V. All-optical inter-layers functional connectivity investigation in the mouse retina. Cell Reports Methods. 2: 100268. PMID 36046629 DOI: 10.1016/j.crmeth.2022.100268  0.787
2022 Pulman J, Sahel JA, Dalkara D. New Editing Tools for Gene Therapy in Inherited Retinal Dystrophies. The Crispr Journal. PMID 35506982 DOI: 10.1089/crispr.2021.0141  0.391
2021 Botto C, Dalkara D, El-Amraoui A. Progress in Gene Editing Tools and Their Potential for Correcting Mutations Underlying Hearing and Vision Loss. Frontiers in Genome Editing. 3: 737632. PMID 34778871 DOI: 10.3389/fgeed.2021.737632  0.362
2021 Varin J, Bouzidi N, Gauvain G, Joffrois C, Desrosiers M, Robert C, De Sousa Dias MM, Neuillé M, Michiels C, Nassisi M, Sahel JA, Picaud S, Audo I, Dalkara D, Zeitz C. Substantial restoration of night vision in adult mice with congenital stationary night blindness. Molecular Therapy. Methods & Clinical Development. 22: 15-25. PMID 34401402 DOI: 10.1016/j.omtm.2021.05.008  0.343
2021 Botto C, Rucli M, Tekinsoy MD, Pulman J, Sahel JA, Dalkara D. Early and late stage gene therapy interventions for inherited retinal degenerations. Progress in Retinal and Eye Research. 100975. PMID 34058340 DOI: 10.1016/j.preteyeres.2021.100975  0.512
2021 Sahel JA, Boulanger-Scemama E, Pagot C, Arleo A, Galluppi F, Martel JN, Esposti SD, Delaux A, de Saint Aubert JB, de Montleau C, Gutman E, Audo I, Duebel J, Picaud S, Dalkara D, et al. Partial recovery of visual function in a blind patient after optogenetic therapy. Nature Medicine. PMID 34031601 DOI: 10.1038/s41591-021-01351-4  0.402
2021 Sahel JA, Grieve K, Pagot C, Authié C, Mohand-Said S, Paques M, Audo I, Becker K, Chaumet-Riffaud AE, Azoulay L, Gutman E, Léveillard T, Zeitz C, Picaud S, Dalkara D, et al. Assessing photoreceptor status in retinal dystrophies: from high resolution imaging to functional vision. American Journal of Ophthalmology. PMID 34000280 DOI: 10.1016/j.ajo.2021.04.013  0.357
2021 Garita-Hernandez M, Chaffiol A, Guibbal L, Routet F, Khabou H, Riancho L, Toualbi L, Picaud S, Sahel JA, Goureau O, Duebel J, Dalkara D. Control of Microbial Opsin Expression in Stem Cell Derived Cones for Improved Outcomes in Cell Therapy. Frontiers in Cellular Neuroscience. 15: 648210. PMID 33815066 DOI: 10.3389/fncel.2021.648210  0.811
2021 Varin J, Bouzidi N, Dias MMS, Pugliese T, Michiels C, Robert C, Desrosiers M, Sahel JA, Audo I, Dalkara D, Zeitz C. Restoration of mGluR6 Localization Following AAV-Mediated Delivery in a Mouse Model of Congenital Stationary Night Blindness. Investigative Ophthalmology & Visual Science. 62: 24. PMID 33729473 DOI: 10.1167/iovs.62.3.24  0.371
2021 Gauvain G, Akolkar H, Chaffiol A, Arcizet F, Khoei MA, Desrosiers M, Jaillard C, Caplette R, Marre O, Bertin S, Fovet CM, Demilly J, Forster V, Brazhnikova E, Hantraye P, ... ... Dalkara D, et al. Optogenetic therapy: high spatiotemporal resolution and pattern discrimination compatible with vision restoration in non-human primates. Communications Biology. 4: 125. PMID 33504896 DOI: 10.1038/s42003-020-01594-w  0.461
2020 Thompson DA, Iannaccone A, Ali RR, Arshavsky VY, Audo I, Bainbridge JWB, Besirli CG, Birch DG, Branham KE, Cideciyan AV, Daiger SP, Dalkara D, Duncan JL, Fahim AT, Flannery JG, et al. Advancing Clinical Trials for Inherited Retinal Diseases: Recommendations from the Second Monaciano Symposium. Translational Vision Science & Technology. 9: 2. PMID 32832209 DOI: 10.1167/Tvst.9.7.2  0.584
2020 Ferrari U, Deny S, Sengupta A, Caplette R, Trapani F, Sahel JA, Dalkara D, Picaud S, Duebel J, Marre O. Towards optogenetic vision restoration with high resolution. Plos Computational Biology. 16: e1007857. PMID 32667921 DOI: 10.1371/Journal.Pcbi.1007857  0.517
2020 Szatko KP, Korympidou MM, Ran Y, Berens P, Dalkara D, Schubert T, Euler T, Franke K. Neural circuits in the mouse retina support color vision in the upper visual field. Nature Communications. 11: 3481. PMID 32661226 DOI: 10.1038/S41467-020-17113-8  0.477
2020 Bertin S, Brazhnikova E, Jaillard C, Sahel JA, Dalkara D. AAV-Mediated Gene Delivery to Foveal Cones. Methods in Molecular Biology (Clifton, N.J.). 2173: 101-112. PMID 32651912 DOI: 10.1007/978-1-0716-0755-8_6  0.649
2020 Byrne LC, Day TP, Visel M, Fortuny C, Dalkara D, Merigan WH, Schaffer DV, Flannery JG. In vivo directed evolution of AAV in the primate retina. Jci Insight. PMID 32271719 DOI: 10.1172/Jci.Insight.135112  0.863
2020 Zhao Z, Klindt DA, Maia Chagas A, Szatko KP, Rogerson L, Protti DA, Behrens C, Dalkara D, Schubert T, Bethge M, Franke K, Berens P, Ecker AS, Euler T. The temporal structure of the inner retina at a single glance. Scientific Reports. 10: 4399. PMID 32157103 DOI: 10.1038/S41598-020-60214-Z  0.424
2020 Barboni MTS, Vaillend C, Joachimsthaler A, Liber AMP, Khabou H, Roux MJ, Vacca O, Vignaud L, Dalkara D, Guillonneau X, Ventura DF, Rendon A, Kremers J. Rescue of Defective Electroretinographic Responses in Dp71-Null Mice With AAV-Mediated Reexpression of Dp71. Investigative Ophthalmology & Visual Science. 61: 11. PMID 32049345 DOI: 10.1167/Iovs.61.2.11  0.827
2020 Garita-Hernandez M, Routet F, Guibbal L, Khabou H, Toualbi L, Riancho L, Reichman S, Duebel J, Sahel JA, Goureau O, Dalkara D. AAV-Mediated Gene Delivery to 3D Retinal Organoids Derived from Human Induced Pluripotent Stem Cells. International Journal of Molecular Sciences. 21. PMID 32028585 DOI: 10.3390/Ijms21030994  0.85
2020 Simon CJ, Sahel JA, Duebel J, Herlitze S, Dalkara D. Opsins for vision restoration. Biochemical and Biophysical Research Communications. PMID 31982136 DOI: 10.1016/J.Bbrc.2019.12.117  0.486
2019 Picaud S, Dalkara D, Marazova K, Goureau O, Roska B, Sahel JA. The primate model for understanding and restoring vision. Proceedings of the National Academy of Sciences of the United States of America. PMID 31871177 DOI: 10.1073/Pnas.1902292116  0.505
2019 Garita-Hernandez M, Lampič M, Chaffiol A, Guibbal L, Routet F, Santos-Ferreira T, Gasparini S, Borsch O, Gagliardi G, Reichman S, Picaud S, Sahel JA, Goureau O, Ader M, Dalkara D, et al. Restoration of visual function by transplantation of optogenetically engineered photoreceptors. Nature Communications. 10: 4524. PMID 31586094 DOI: 10.1038/S41467-019-12330-2  0.836
2019 Devoldere J, Peynshaert K, Dewitte H, Vanhove C, De Groef L, Moons L, Özcan SY, Dalkara D, De Smedt SC, Remaut K. Non-viral delivery of chemically modified mRNA to the retina: Subretinal versus intravitreal administration. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 31265881 DOI: 10.1016/J.Jconrel.2019.06.042  0.425
2019 Hamon A, García-García D, Ail D, Bitard J, Chesneau A, Dalkara D, Locker M, Roger JE, Perron M. Linking YAP to Müller Glia Quiescence Exit in the Degenerative Retina. Cell Reports. 27: 1712-1725.e6. PMID 31067458 DOI: 10.1016/J.Celrep.2019.04.045  0.491
2019 Chen IW, Ronzitti E, Lee BR, Daigle TL, Dalkara D, Zeng H, Emiliani V, Papagiakoumou E. sub-millisecond two-photon optogenetics with temporally focused patterned light. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30833505 DOI: 10.1523/Jneurosci.1785-18.2018  0.342
2019 Sahel JA, Dalkara D. Gene therapy for retinal dystrophy. Nature Medicine. 25: 198-199. PMID 30718907 DOI: 10.1038/S41591-019-0346-1  0.547
2018 Garita-Hernandez M, Guibbal L, Toualbi L, Routet F, Chaffiol A, Winckler C, Harinquet M, Robert C, Fouquet S, Bellow S, Sahel JA, Goureau O, Duebel J, Dalkara D. Optogenetic Light Sensors in Human Retinal Organoids. Frontiers in Neuroscience. 12: 789. PMID 30450028 DOI: 10.3389/Fnins.2018.00789  0.848
2018 Quinn PM, Mulder AA, Henrique Alves C, Desrosiers M, Vries SI, Klooster J, Dalkara D, Koster AJ, Jost CR, Wijnholds J. Loss of CRB2 in Müller glial cells modifies a CRB1-associated retinitis pigmentosa phenotype into a Leber congenital amaurosis phenotype. Human Molecular Genetics. PMID 30239717 DOI: 10.1093/Hmg/Ddy337  0.577
2018 Khabou H, Cordeau C, Pacot L, Fisson S, Dalkara D. Dosage thresholds and influence of transgene cassette in AAV-related toxicity. Human Gene Therapy. PMID 30132368 DOI: 10.1089/hum.2018.144  0.829
2018 Khabou H, Garita-Hernandez M, Chaffiol A, Reichman S, Jaillard C, Brazhnikova E, Bertin S, Forster V, Desrosiers M, Winckler C, Goureau O, Picaud S, Duebel J, Sahel JA, Dalkara D. Noninvasive gene delivery to foveal cones for vision restoration. Jci Insight. 3. PMID 29367457 DOI: 10.1172/Jci.Insight.96029  0.843
2018 Desrosiers M, Dalkara D. Neutralizing Antibodies Against Adeno-Associated Virus (AAV): Measurement and Influence on Retinal Gene Delivery. Methods in Molecular Biology (Clifton, N.J.). 1715: 225-238. PMID 29188517 DOI: 10.1007/978-1-4939-7522-8_16  0.519
2017 Joly S, Dalkara D, Pernet V. Sphingosine 1-Phosphate Receptor 1 Modulates CNTF-Induced Axonal Growth and Neuroprotection in the Mouse Visual System. Neural Plasticity. 2017: 6818970. PMID 29234527 DOI: 10.1155/2017/6818970  0.435
2017 Planul A, Dalkara D. Vectors and Gene Delivery to the Retina. Annual Review of Vision Science. 3: 121-140. PMID 28937950 DOI: 10.1146/annurev-vision-102016-061413  0.467
2017 Chaffiol A, Caplette R, Jaillard C, Brazhnikova E, Desrosiers M, Dubus E, Duhamel L, Macé E, Marre O, Benoit P, Hantraye P, Bemelmans AP, Bamberg E, Duebel J, Sahel JA, ... ... Dalkara D, et al. A New Promoter Allows Optogenetic Vision Restoration with Enhanced Sensitivity in Macaque Retina. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28807567 DOI: 10.1016/J.Ymthe.2017.07.011  0.479
2016 Scholl HP, Strauss RW, Singh MS, Dalkara D, Roska B, Picaud S, Sahel JA. Emerging therapies for inherited retinal degeneration. Science Translational Medicine. 8: 368rv6. PMID 27928030 DOI: 10.1126/Scitranslmed.Aaf2838  0.595
2016 Khabou H, Desrosiers M, Winckler C, Fouquet S, Auregan G, Bemelmans AP, Sahel JA, Dalkara D. Cover Image, Volume 113, Number 12, December 2016. Biotechnology and Bioengineering. 113: i. PMID 27788308 DOI: 10.1002/bit.25806  0.786
2016 Sengupta A, Chaffiol A, Macé E, Caplette R, Desrosiers M, Lampič M, Forster V, Marre O, Lin JY, Sahel JA, Picaud S, Dalkara D, Duebel J. Red-shifted channelrhodopsin stimulation restores light responses in blind mice, macaque retina, and human retina. Embo Molecular Medicine. PMID 27679671 DOI: 10.15252/Emmm.201505699  0.521
2016 Vacca O, Charles-Messance H, El Mathari B, Sene A, Barbe P, Fouquet S, Aragón J, Darche M, Giocanti-Aurégan A, Paques M, Sahel JA, Tadayoni R, Montañez C, Dalkara D, Rendon A. AAV-mediated gene therapy in Dystrophin-Dp71 deficient mouse leads to blood-retinal barrier restoration and edema reabsorption. Human Molecular Genetics. PMID 27288449 DOI: 10.1093/Hmg/Ddw159  0.587
2016 Khabou H, Desrosiers M, Winckler C, Fouquet S, Auregan G, Bemelmans AP, Sahel JA, Dalkara D. Insight into the mechanisms of enhanced retinal transduction by the engineered AAV2 capsid variant -7m8. Biotechnology and Bioengineering. PMID 27259396 DOI: 10.1002/Bit.26031  0.808
2016 Spoida K, Eickelbeck D, Karapinar R, Eckhardt T, Mark MD, Jancke D, Ehinger BV, König P, Dalkara D, Herlitze S, Masseck OA. Melanopsin Variants as Intrinsic Optogenetic On and Off Switches for Transient versus Sustained Activation of G Protein Pathways. Current Biology : Cb. PMID 27068418 DOI: 10.1016/J.Cub.2016.03.007  0.314
2016 Mei X, Chaffiol A, Kole C, Yang Y, Millet-Puel G, Clérin E, Aït-Ali N, Bennett J, Dalkara D, Sahel JA, Duebel J, Leveillard T. The thioredoxin encoded by the Rod-derived Cone Viability Factor gene protects cone photoreceptors against oxidative stress. Antioxidants & Redox Signaling. PMID 27025156 DOI: 10.1089/ars.2015.6509  0.46
2016 Dalkara D, Goureau O, Marazova K, Sahel JA. Let there be light: gene and cell therapy for blindness. Human Gene Therapy. PMID 26751519 DOI: 10.1089/Hum.2015.147  0.579
2016 Dalkara D. Stem cells lead the blind Science Translational Medicine. 8. DOI: 10.1126/Scitranslmed.Aaf0858  0.435
2016 Douar AM, Bouquet C, Pruneau D, Chavas J, Dalkara D, Duebel J, Benosman R, Chenegros G, Picaud S, Sahel J, Thomasson N. 268. Optogenetic Engineering of Retinal Ganglion Cells with AAV2.7m8-ChrimsonR-tdTomato (GS030-DP) Is Well Tolerated and Induces Functional Responses to Light in Non-Human Primates Molecular Therapy. 24: S106-S107. DOI: 10.1016/S1525-0016(16)33077-5  0.508
2015 Khabou H, Dalkara D. [Developments in gene delivery vectors for ocular gene therapy]. MéDecine Sciences : M/S. 31: 529-37. PMID 26059304 DOI: 10.1051/Medsci/20153105015  0.857
2015 Orhan E, Dalkara D, Neuillé M, Lechauve C, Michiels C, Picaud S, Léveillard T, Sahel JA, Naash MI, Lavail MM, Zeitz C, Audo I. Genotypic and phenotypic characterization of P23H line 1 rat model. Plos One. 10: e0127319. PMID 26009893 DOI: 10.1371/Journal.Pone.0127319  0.424
2015 Aït-Ali N, Fridlich R, Millet-Puel G, Clérin E, Delalande F, Jaillard C, Blond F, Perrocheau L, Reichman S, Byrne LC, Olivier-Bandini A, Bellalou J, Moyse E, Bouillaud F, Nicol X, ... Dalkara D, et al. Rod-derived cone viability factor promotes cone survival by stimulating aerobic glycolysis. Cell. 161: 817-32. PMID 25957687 DOI: 10.1016/J.Cell.2015.03.023  0.726
2015 Vacca O, El Mathari B, Darche M, Sahel JA, Rendon A, Dalkara D. Using Adeno-associated Virus as a Tool to Study Retinal Barriers in Disease. Journal of Visualized Experiments : Jove. PMID 25938717 DOI: 10.3791/52451  0.592
2015 Dalkara D, Duebel J, Sahel JA. Gene therapy for the eye focus on mutation-independent approaches. Current Opinion in Neurology. 28: 51-60. PMID 25545056 DOI: 10.1097/Wco.0000000000000168  0.412
2015 Byrne LC, Dalkara D, Luna G, Fisher SK, Clérin E, Sahel JA, Léveillard T, Flannery JG. Viral-mediated RdCVF and RdCVFL expression protects cone and rod photoreceptors in retinal degeneration. The Journal of Clinical Investigation. 125: 105-16. PMID 25415434 DOI: 10.1172/Jci65654  0.856
2015 Vajda F, Jordi N, Dalkara D, Joly S, Christ F, Tews B, Schwab ME, Pernet V. Cell type-specific Nogo-A gene ablation promotes axonal regeneration in the injured adult optic nerve. Cell Death and Differentiation. 22: 323-35. PMID 25257170 DOI: 10.1038/Cdd.2014.147  0.404
2015 Macé E, Caplette R, Marre O, Sengupta A, Chaffiol A, Barbe P, Desrosiers M, Bamberg E, Sahel JA, Picaud S, Duebel J, Dalkara D. Targeting channelrhodopsin-2 to ON-bipolar cells with vitreally administered AAV Restores ON and OFF visual responses in blind mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 7-16. PMID 25095892 DOI: 10.1038/Mt.2014.154  0.634
2015 Dalkara D. Gene therapy hide and seek Science Translational Medicine. 7. DOI: 10.1126/Scitranslmed.Aad4447  0.454
2015 Dalkara D. Boosting the success of retinal gene therapy Science Translational Medicine. 7. DOI: 10.1126/Scitranslmed.Aad3065  0.643
2015 Dalkara D. Cutting down on sense makes sense for gene silencing Science Translational Medicine. 7. DOI: 10.1126/Scitranslmed.Aac9738  0.346
2015 Dalkara D. Baby steps in gene therapy Science Translational Medicine. 7. DOI: 10.1126/Scitranslmed.Aac7151  0.417
2015 Dalkara D. AAV and gene therapy: It's complicated Science Translational Medicine. 7. DOI: 10.1126/Scitranslmed.Aab3969  0.435
2015 Aït-Ali N, Fridlich R, Millet-Puel G, Clérin E, Delalande F, Jaillard C, Blond F, Perrocheau L, Reichman S, Byrne LC, Olivier-Bandini A, Bellalou J, Moyse E, Bouillaud F, Nicol X, ... Dalkara D, et al. Rod-derived cone viability factor promotes cone survival by stimulating aerobic glycolysis Cell. 161: 817-832. DOI: 10.1016/j.cell.2015.03.023  0.678
2014 Bockstael O, Tenenbaum L, Dalkara D, Melas C, De Witte O, Levivier M, Chtarto A. Intracisternal delivery of NFκB-inducible scAAV2/9 reveals locoregional neuroinflammation induced by systemic kainic acid treatment. Frontiers in Molecular Neuroscience. 7: 92. PMID 25520614 DOI: 10.3389/Fnmol.2014.00092  0.348
2014 Yin L, Masella B, Dalkara D, Zhang J, Flannery JG, Schaffer DV, Williams DR, Merigan WH. Imaging light responses of foveal ganglion cells in the living macaque eye. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 6596-605. PMID 24806684 DOI: 10.1523/Jneurosci.4438-13.2014  0.739
2014 Dalkara D, Sahel JA. Gene therapy for inherited retinal degenerations. Comptes Rendus Biologies. 337: 185-92. PMID 24702845 DOI: 10.1016/j.crvi.2014.01.002  0.455
2014 Byrne LC, Oztürk BE, Lee T, Fortuny C, Visel M, Dalkara D, Schaffer DV, Flannery JG. Retinoschisin gene therapy in photoreceptors, Müller glia or all retinal cells in the Rs1h-/- mouse. Gene Therapy. 21: 585-92. PMID 24694538 DOI: 10.1038/Gt.2014.31  0.873
2014 Vacca O, Darche M, Schaffer DV, Flannery JG, Sahel JA, Rendon A, Dalkara D. AAV-mediated gene delivery in Dp71-null mouse model with compromised barriers. Glia. 62: 468-76. PMID 24382652 DOI: 10.1002/Glia.22617  0.762
2013 Pernet V, Joly S, Jordi N, Dalkara D, Guzik-Kornacka A, Flannery JG, Schwab ME. Misguidance and modulation of axonal regeneration by Stat3 and Rho/ROCK signaling in the transparent optic nerve. Cell Death & Disease. 4: e734. PMID 23868067 DOI: 10.1038/Cddis.2013.266  0.569
2013 Dalkara D, Byrne LC, Klimczak RR, Visel M, Yin L, Merigan WH, Flannery JG, Schaffer DV. In vivo-directed evolution of a new adeno-associated virus for therapeutic outer retinal gene delivery from the vitreous. Science Translational Medicine. 5: 189ra76. PMID 23761039 DOI: 10.1126/Scitranslmed.3005708  0.859
2013 Sahel JA, Léveillard T, Picaud S, Dalkara D, Marazova K, Safran A, Paques M, Duebel J, Roska B, Mohand-Said S. Functional rescue of cone photoreceptors in retinitis pigmentosa. Graefe's Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv FüR Klinische Und Experimentelle Ophthalmologie. 251: 1669-77. PMID 23575948 DOI: 10.1007/S00417-013-2314-7  0.505
2013 Pernet V, Joly S, Dalkara D, Jordi N, Schwarz O, Christ F, Schaffer DV, Flannery JG, Schwab ME. Long-distance axonal regeneration induced by CNTF gene transfer is impaired by axonal misguidance in the injured adult optic nerve. Neurobiology of Disease. 51: 202-13. PMID 23194670 DOI: 10.1016/J.Nbd.2012.11.011  0.667
2013 Yin L, Masella BD, Geng Y, Dalkara D, Osakada F, Sharma R, Zhang J, Cetin AH, Callaway EM, Flannery JG, Schaffer DV, Williams DR, Merigan WH. Optical recording of the light response of ganglion cells in the living eye Optics Infobase Conference Papers. DOI: 10.1364/Fio.2013.Ftu4I.3  0.713
2012 Dehay B, Dalkara D, Dovero S, Li Q, Bezard E. Systemic scAAV9 variant mediates brain transduction in newborn rhesus macaques. Scientific Reports. 2: 253. PMID 22355765 DOI: 10.1038/Srep00253  0.305
2012 Pernet V, Joly S, Dalkara D, Schwarz O, Christ F, Schaffer D, Flannery JG, Schwab ME. Neuronal Nogo-A upregulation does not contribute to ER stress-associated apoptosis but participates in the regenerative response in the axotomized adult retina. Cell Death and Differentiation. 19: 1096-108. PMID 22193546 DOI: 10.1038/Cdd.2011.191  0.697
2012 Dalkara D, Byrne LC, Lee T, Hoffmann NV, Schaffer DV, Flannery JG. Enhanced gene delivery to the neonatal retina through systemic administration of tyrosine-mutated AAV9. Gene Therapy. 19: 176-81. PMID 22011645 DOI: 10.1038/Gt.2011.163  0.87
2012 Yin L, Masella B, Dalkara D, Flannery JG, Schaffer DV, Williams DR, Merigan WH. In vivo imaging of ganglion cell physiology in macaque fovea using a calcium indicator Journal of Vision. 12: 55-55. DOI: 10.1167/12.14.55  0.663
2011 Caporale N, Kolstad KD, Lee T, Tochitsky I, Dalkara D, Trauner D, Kramer R, Dan Y, Isacoff EY, Flannery JG. LiGluR restores visual responses in rodent models of inherited blindness. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1212-9. PMID 21610698 DOI: 10.1038/Mt.2011.103  0.841
2011 Dalkara D, Kolstad KD, Guerin KI, Hoffmann NV, Visel M, Klimczak RR, Schaffer DV, Flannery JG. AAV mediated GDNF secretion from retinal glia slows down retinal degeneration in a rat model of retinitis pigmentosa. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1602-8. PMID 21522134 DOI: 10.1038/Mt.2011.62  0.838
2011 Yin L, Greenberg K, Hunter JJ, Dalkara D, Kolstad KD, Masella BD, Wolfe R, Visel M, Stone D, Libby RT, Diloreto D, Schaffer D, Flannery J, Williams DR, Merigan WH. Intravitreal injection of AAV2 transduces macaque inner retina. Investigative Ophthalmology & Visual Science. 52: 2775-83. PMID 21310920 DOI: 10.1167/Iovs.10-6250  0.826
2010 Kolstad KD, Dalkara D, Guerin K, Visel M, Hoffmann N, Schaffer DV, Flannery JG. Changes in adeno-associated virus-mediated gene delivery in retinal degeneration. Human Gene Therapy. 21: 571-8. PMID 20021232 DOI: 10.1089/Hum.2009.194  0.838
2010 Yin L, Dalkara D, Greenberg K, Hunter JJ, Masella BD, Visel M, DiLoreto Jr. D, Flannery J, Williams DR, Merigan WH. AAV-mediated gene delivery to retinal ganglion cells in the macaque eye Journal of Vision. 10: 66-66. DOI: 10.1167/10.15.66  0.859
2009 Klimczak RR, Koerber JT, Dalkara D, Flannery JG, Schaffer DV. A novel adeno-associated viral variant for efficient and selective intravitreal transduction of rat Müller cells. Plos One. 4: e7467. PMID 19826483 DOI: 10.1371/Journal.Pone.0007467  0.844
2009 Dalkara D, Kolstad KD, Caporale N, Visel M, Klimczak RR, Schaffer DV, Flannery JG. Inner limiting membrane barriers to AAV-mediated retinal transduction from the vitreous. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 2096-102. PMID 19672248 DOI: 10.1038/Mt.2009.181  0.838
2009 Koerber JT, Klimczak R, Jang JH, Dalkara D, Flannery JG, Schaffer DV. Molecular evolution of adeno-associated virus for enhanced glial gene delivery. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 2088-95. PMID 19672246 DOI: 10.1038/Mt.2009.184  0.824
2006 Fraley AW, Pons B, Dalkara D, Nullans G, Behr JP, Zuber G. Cationic oligonucleotide-peptide conjugates with aggregating properties enter efficiently into cells while maintaining hybridization properties and enzymatic recognition. Journal of the American Chemical Society. 128: 10763-71. PMID 16910671 DOI: 10.1021/Ja060873E  0.771
2004 Dalkara D, Zuber G, Behr JP. Intracytoplasmic delivery of anionic proteins. Molecular Therapy : the Journal of the American Society of Gene Therapy. 9: 964-9. PMID 15194063 DOI: 10.1016/J.Ymthe.2004.03.007  0.555
Low-probability matches (unlikely to be authored by this person)
2014 Masseck OA, Spoida K, Dalkara D, Maejima T, Rubelowski JM, Wallhorn L, Deneris ES, Herlitze S. Vertebrate cone opsins enable sustained and highly sensitive rapid control of Gi/o signaling in anxiety circuitry. Neuron. 81: 1263-73. PMID 24656249 DOI: 10.1016/J.Neuron.2014.01.041  0.299
2015 Dalkara D. Muscle memory helps with heartache Science Translational Medicine. 7. DOI: 10.1126/Scitranslmed.Aad8020  0.29
2019 Prévot P, Gauvain G, Akolkar H, Khoei MA, Gehere K, LeMer Y, Fovet C, Hantraye P, Bertin S, Brazhnikova E, Nouvel-Jaillard C, Duebel J, Dalkara D, Pouget P, Sahel J, et al. Visual restoration by an infrared photovoltaic implant and by optogenetic therapy: validation in non-human primates Journal of Vision. 19: 48. DOI: 10.1167/19.8.48  0.285
2012 Mourot A, Fehrentz T, Le Feuvre Y, Smith CM, Herold C, Dalkara D, Nagy F, Trauner D, Kramer RH. Rapid optical control of nociception with an ion-channel photoswitch. Nature Methods. 9: 396-402. PMID 22343342 DOI: 10.1038/Nmeth.1897  0.283
2023 Sahel JA, Marazova K, Dalkara D. Gene augmentation in FAM161A ciliopathy: Toward functional vision rescue. Molecular Therapy : the Journal of the American Society of Gene Therapy. 31: 2820-2822. PMID 37729904 DOI: 10.1016/j.ymthe.2023.09.005  0.267
2016 Dalkara D. Smart CRISPR-Cas9 liver delivery repairs a genetic defect Science Translational Medicine. 8. DOI: 10.1126/Scitranslmed.Aaf3854  0.257
2022 Lacomme M, Hales SC, Brown TW, Stevanovic K, Jolicoeur C, Cai J, Bois T, Desrosiers M, Dalkara D, Cayouette M. Numb regulates Tau levels and prevents neurodegeneration in tauopathy mouse models. Science Advances. 8: eabm4295. PMID 36260685 DOI: 10.1126/sciadv.abm4295  0.256
2022 Ail D, Ren D, Brazhnikova E, Nouvel-Jaillard C, Bertin S, Mirashrafi SB, Fisson S, Dalkara D. Systemic and local immune responses to intraocular AAV vector administration in non-human primates. Molecular Therapy. Methods & Clinical Development. 24: 306-316. PMID 35229004 DOI: 10.1016/j.omtm.2022.01.011  0.237
2021 Jaillard C, Ouechtati F, Clérin E, Millet-Puel G, Corsi M, Aït-Ali N, Blond F, Chevy Q, Gales L, Farinelli M, Dalkara D, Sahel JA, Portais JC, Poncer JC, Léveillard T. The metabolic signaling of the nucleoredoxin-like 2 gene supports brain function. Redox Biology. 48: 102198. PMID 34856436 DOI: 10.1016/j.redox.2021.102198  0.228
2007 Chittimalla C, Dalkara D, Zuber G. Design, synthesis and evaluation of a novel polymer for gene delivery to mammalian cells Letters in Drug Design and Discovery. 4: 92-98. DOI: 10.2174/157018007779422569  0.227
2012 Dalkara D. Gene therapy explodes in ophthalmology | La thérapie génique explose en ophtalmologie Biofutur. 38-42.  0.225
2023 Cadoni S, Demené C, Alcala I, Provansal M, Nguyen D, Nelidova D, Labernède G, Lubetzki J, Goulet R, Burban E, Dégardin J, Simonutti M, Gauvain G, Arcizet F, Marre O, ... Dalkara D, et al. Ectopic expression of a mechanosensitive channel confers spatiotemporal resolution to ultrasound stimulations of neurons for visual restoration. Nature Nanotechnology. PMID 37012508 DOI: 10.1038/s41565-023-01359-6  0.192
2007 Courtête J, Sibler AP, Zeder-Lutz G, Dalkara D, Oulad-Abdelghani M, Zuber G, Weiss E. Suppression of cervical carcinoma cell growth by intracytoplasmic codelivery of anti-oncoprotein E6 antibody and small interfering RNA. Molecular Cancer Therapeutics. 6: 1728-35. PMID 17575104 DOI: 10.1158/1535-7163.MCT-06-0808  0.177
2006 Dalkara D, Chandrashekhar C, Zuber G. Intracellular protein delivery with a dimerizable amphiphile for improved complex stability and prolonged protein release in the cytoplasm of adherent cell lines. Journal of Controlled Release : Official Journal of the Controlled Release Society. 116: 353-9. PMID 17097756 DOI: 10.1016/j.jconrel.2006.10.005  0.14
2023 Nemoto T, Ocari T, Planul A, Tekinsoy M, Zin EA, Dalkara D, Ferrari U. ACIDES: on-line monitoring of forward genetic screens for protein engineering. Nature Communications. 14: 8504. PMID 38148337 DOI: 10.1038/s41467-023-43967-9  0.136
2015 Mark MD, Krause M, Boele HJ, Kruse W, Pollok S, Kuner T, Dalkara D, Koekkoek S, De Zeeuw CI, Herlitze S. Spinocerebellar Ataxia Type 6 Protein Aggregates Cause Deficits in Motor Learning and Cerebellar Plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 8882-95. PMID 26063920 DOI: 10.1523/Jneurosci.0891-15.2015  0.077
2021 Dongelmans M, Durand-de Cuttoli R, Nguyen C, Come M, Duranté EK, Lemoine D, Brito R, Ahmed Yahia T, Mondoloni S, Didienne S, Bousseyrol E, Hannesse B, Reynolds LM, Torquet N, Dalkara D, et al. Chronic nicotine increases midbrain dopamine neuron activity and biases individual strategies towards reduced exploration in mice. Nature Communications. 12: 6945. PMID 34836948 DOI: 10.1038/s41467-021-27268-7  0.074
2021 Nguyen C, Mondoloni S, Le Borgne T, Centeno I, Come M, Jehl J, Solié C, Reynolds LM, Durand-de Cuttoli R, Tolu S, Valverde S, Didienne S, Hannesse B, Fiancette JF, Pons S, ... ... Dalkara D, et al. Nicotine inhibits the VTA-to-amygdala dopamine pathway to promote anxiety. Neuron. PMID 34242565 DOI: 10.1016/j.neuron.2021.06.013  0.074
Hide low-probability matches.