Shane R Stecklein - Publications

Affiliations: 
The University of Kansas Cancer Center 
Area:
Breast Cancer, Lymphoma, Radiation Biology

57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Martín M, Yoder R, Salgado R, Del Monte-Millán M, Alvarez EL, Echavarría I, Staley JM, O'Dea AP, Nye LE, Stecklein SR, Bueno Muiño C, Jerez-Gilarranz Y, Cebollero M, Bueno O, Garcia-Saenz JÁ, et al. Tumor-infiltrating lymphocytes refine outcomes in triple-negative breast cancer treated with anthracycline-free neoadjuvant chemotherapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 38466643 DOI: 10.1158/1078-0432.CCR-24-0106  0.436
2023 Sharma P, Stecklein SR, Yoder R, Staley JM, Schwensen K, O'Dea A, Nye L, Satelli D, Crane G, Madan R, O'Neil MF, Wagner J, Larson KE, Balanoff C, Kilgore L, et al. Clinical and Biomarker Findings of Neoadjuvant Pembrolizumab and Carboplatin Plus Docetaxel in Triple-Negative Breast Cancer: NeoPACT Phase 2 Clinical Trial. Jama Oncology. PMID 37991778 DOI: 10.1001/jamaoncol.2023.5033  0.474
2023 Stecklein SR, Barlow W, Pusztai L, Timms K, Kennedy R, Logan GE, Seitz R, Badve S, Gökmen-Polar Y, Porter P, Linden H, Tripathy D, Hortobagyi GN, Godwin AK, Thompson A, et al. Dual Prognostic Classification of Triple-Negative Breast Cancer by DNA Damage Immune Response and Homologous Recombination Deficiency. Jco Precision Oncology. 7: e2300197. PMID 37972336 DOI: 10.1200/PO.23.00197  0.429
2023 Machiels M, Oulkadi R, Tramm T, Stecklein SR, Somaiah N, De Caluwé A, Klein J, Tran WT, Salgado R. Individualising radiation therapy decisions in breast cancer patients based on tumour infiltrating lymphocytes and genomic biomarkers. Breast (Edinburgh, Scotland). 71: 13-21. PMID 37437386 DOI: 10.1016/j.breast.2023.06.010  0.413
2023 Jagsi R, Barlow WE, Woodward WA, Connolly E, Mahtani R, Shumway D, Speers C, Stecklein SR, Zeidan Y, Zhang H, Sharma P, Pusztai L, Hortobagyi GN, Kalinsky K. Radiotherapy Use and Incidence of Locoregional Recurrence in Patients With Favorable-Risk, Node-Positive Breast Cancer Enrolled in the SWOG S1007 Trial. Jama Oncology. PMID 37410451 DOI: 10.1001/jamaoncol.2023.1984  0.553
2023 Stecklein SR, Kimler BF, Yoder R, Schwensen K, Staley JM, Khan QJ, O'Dea AP, Nye LE, Elia M, Heldstab J, Home T, Hyter S, Isakova K, Pathak HB, Godwin AK, et al. ctDNA and residual cancer burden are prognostic in triple-negative breast cancer patients with residual disease. Npj Breast Cancer. 9: 10. PMID 36878909 DOI: 10.1038/s41523-023-00512-7  0.356
2022 Subham S, Jeppson JD, Worcester C, Schatmeyer B, Zhao J, Madan R, Lakis NS, Kimler BF, McGuirk JP, Chen RC, Stecklein SR, Akhavan D. EGFR as a potent CAR T target in triple negative breast cancer brain metastases. Breast Cancer Research and Treatment. PMID 36318382 DOI: 10.1007/s10549-022-06783-1  0.349
2022 Yoder R, Kimler BF, Staley JM, Schwensen K, Wang YY, Finke K, O'Dea A, Nye L, Elia M, Crane G, McKittrick R, Pluenneke R, Madhusudhana S, Beck L, Shrestha A, ... ... Stecklein SR, et al. Impact of low versus negative estrogen/progesterone receptor status on clinico-pathologic characteristics and survival outcomes in HER2-negative breast cancer. Npj Breast Cancer. 8: 80. PMID 35817765 DOI: 10.1038/s41523-022-00448-4  0.403
2022 Abuhadra N, Stecklein S, Sharma P, Moulder S. Early-stage Triple-negative Breast Cancer: Time to Optimize Personalized Strategies. The Oncologist. 27: 30-39. PMID 35305094 DOI: 10.1093/oncolo/oyab003  0.466
2021 Chapman BV, Liu D, Shen Y, Olamigoke OO, Lakomy DS, Barrera AMG, Stecklein SR, Sawakuchi GO, Bright SJ, Bedrosian I, Litton JK, Smith BD, Woodward WA, Perkins GH, Hoffman KE, et al. Outcomes after breast radiotherapy in a diverse patient cohort with a germline BRCA1/2 mutation. International Journal of Radiation Oncology, Biology, Physics. PMID 34610390 DOI: 10.1016/j.ijrobp.2021.09.033  0.61
2021 Chapman BV, Liu D, Shen Y, Olamigoke OO, Lakomy DS, Barrera AMG, Stecklein SR, Sawakuchi GO, Bright SJ, Bedrosian I, Litton JK, Smith BD, Woodward WA, Perkins GH, Hoffman KE, et al. Breast radiotherapy-related treatment outcomes in patients with or without germline mutations on multigene panel testing. International Journal of Radiation Oncology, Biology, Physics. PMID 34582940 DOI: 10.1016/j.ijrobp.2021.09.026  0.616
2021 Villodre ES, Hu X, Larson R, Finetti P, Gomez K, Balema W, Stecklein SR, Santiago-Sanchez G, Krishnamurthy S, Song J, Su X, Ueno NT, Tripathy D, Van Laere S, Bertucci F, et al. Lipocalin 2 promotes inflammatory breast cancer tumorigenesis and skin invasion. Molecular Oncology. PMID 34342930 DOI: 10.1002/1878-0261.13074  0.608
2021 Sharma P, Abramson VG, O'Dea AP, Nye L, Mayer IA, Pathak HB, Hoffmann M, Stecklein SR, Elia M, Lewis S, Scott J, De Jong JA, Wang YY, Yoder R, Schwensen K, et al. Clinical and biomarker results from phase I/II study of PI3K inhibitor alpelisib plus nab-paclitaxel in HER2-negative metastatic breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 33602685 DOI: 10.1158/1078-0432.CCR-20-4879  0.508
2020 Stecklein SR, Sharma P. Last but not Least: Antibody-Drug Conjugates in Hormone Receptor-Positive Metastatic Breast Cancer. Annals of Oncology : Official Journal of the European Society For Medical Oncology. PMID 33038485 DOI: 10.1016/j.annonc.2020.10.001  0.393
2020 Balema W, Larson R, Whye RV, Ye R, Ning J, Rahal O, Stecklein S, Krishnamurthy S, El-Zein R, Woodward W. Abstract P6-15-04: Modeling limited breastfeeding and diet on IBC like tumor progression Cancer Research. DOI: 10.1158/1538-7445.Sabcs19-P6-15-04  0.422
2020 Rahal O, Stecklein S, Larson R, Van Wyhe R, Villodre E, Debeb B, Woodward W. Protein Kinase C Zeta (PKCζ) Knockdown Increases Radiation Sensitivity and Reduces Brain Colonization of HER2-Neu Overexpressing Inflammatory Breast Cancer Cells International Journal of Radiation Oncology*Biology*Physics. 108: S24. DOI: 10.1016/j.ijrobp.2020.07.2112  0.584
2019 Stecklein SR, Rosso KJ, Nuanjing J, Tadros AB, Weiss A, DeSnyder SM, Kuerer HM, Teshome M, Buchholz TA, Stauder MC, Ueno NT, Lucci A, Woodward WA. Excellent Locoregional Control in Inflammatory Breast Cancer with a Personalized Radiotherapy Approach. Practical Radiation Oncology. PMID 31132433 DOI: 10.1016/J.Prro.2019.05.011  0.624
2019 Stecklein SR, Bloom ES. Reply to the Letter to the Editor "Regarding: Prospective Comparison of Toxicity and Cosmetic Outcome After Accelerated Partial Breast Irradiation with Conformal External Beam Radiotherapy or Single-Entry Multilumen Intracavitary Brachytherapy". Practical Radiation Oncology. PMID 30709648 DOI: 10.1016/J.Prro.2018.10.011  0.436
2019 Chapman BSV, Liu DD, Stecklein SR, Gutierrez Barrera A, Woodward WA, Sawakuchi GO, Arun B, Shaitelman SF. Outcomes after adjuvant radiotherapy in breast cancer patients with and without germline mutations: A large, single-institutional experience. Journal of Clinical Oncology. 37: 1502-1502. DOI: 10.1200/Jco.2019.37.15_Suppl.1502  0.685
2019 Villodre E, Larson R, Hu X, Stecklein S, Gomez K, Finetti P, Krishnamurthy S, Ivan C, Su X, Ueno N, Laere SV, Bertucci F, Tripathy D, Vivas-Mejía P, Woodward WA, et al. Abstract P2-01-03: Lipocalin 2 promotes inflammatory breast cancer tumorigenesis and skin invasion Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-P2-01-03  0.568
2019 Chapman B, Liu D, Stecklein S, Barrera AMG, Woodward W, Sawakuchi G, Arun B, Shaitelman S. Germline BRCA1/2 Mutation Status Is Not Associated with Differential Radiation Responsiveness in Patients with Locally Advanced Breast Cancer International Journal of Radiation Oncology*Biology*Physics. 105: S42-S43. DOI: 10.1016/J.Ijrobp.2019.06.465  0.663
2019 Rahal O, Woodward WA, Stecklein SR, Wyhe RDV, Larson R. Microenviroment-mediated Induction of Protein Kinase C – zeta in Breast Inflammatory Carcinoma Cells as a Possible Mediator of Radioresistance. International Journal of Radiation Oncology Biology Physics. 105. DOI: 10.1016/J.Ijrobp.2019.06.1000  0.56
2018 Stecklein SR, Shaitelman SF, Babiera GV, Bedrosian I, Black DM, Ballo MT, Arzu I, Strom EA, Reed VK, Dvorak T, Smith BD, Woodward WA, Hoffman KE, Schlembach PJ, Kirsner SM, et al. Prospective Comparison of Toxicity and Cosmetic Outcome After Accelerated Partial Breast Irradiation with Conformal External Beam Radiotherapy or Single-Entry Multilumen Intracavitary Brachytherapy. Practical Radiation Oncology. PMID 30125673 DOI: 10.1016/J.Prro.2018.08.003  0.59
2018 Stecklein SR, Park M, Liu DD, Valle Goffin JJ, Caudle AS, Mittendorf EA, Barcenas CH, Mougalian S, Woodward WA, Valero V, Sahin AA, Yang WT, Shaitelman SF. Long-Term Impact of Regional Nodal Irradiation in Patients with Node-Positive Breast Cancer Treated with Neoadjuvant Systemic Therapy. International Journal of Radiation Oncology, Biology, Physics. PMID 29928946 DOI: 10.1016/J.Ijrobp.2018.06.016  0.635
2018 Stecklein SR, Frumovitz M, Klopp AH, Gunther JR, Eifel PJ. Effectiveness of definitive radiotherapy for squamous cell carcinoma of the vulva with gross inguinal lymphadenopathy. Gynecologic Oncology. PMID 29336837 DOI: 10.1016/J.Ygyno.2018.01.007  0.33
2018 Stecklein S, Babiera G, Bedrosian I, Shaitelman S, Ballo M, Tereffe W, Arzu I, Perkins G, Strom E, Reed V, Dvorak T, Smith B, Woodward W, Hoffman K, Schlembach P, et al. Abstract P2-11-12: Prospective comparison of late toxicity and cosmetic outcome after accelerated partial breast irradiation with conformal external beam radiotherapy or single-entry multi-lumen intracavitary brachytherapy Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P2-11-12  0.609
2018 Stecklein SR, Wolfe AR, Debeb BG, Larson RA, Woodward WA. Abstract 2397: Intracellular cholesterol regulates the DNA damage response in inflammatory breast cancer Cancer Research. 78: 2397-2397. DOI: 10.1158/1538-7445.Am2018-2397  0.577
2018 Stecklein SR, Rosso KJ, Tadros AB, Weiss A, DeSnyder SM, Kuerer HM, Buchholz TA, Stauder MC, Ueno NT, Lucci A, Woodward WA. Excellent Locoregional Control in Inflammatory Breast Cancer with a Personalized Radiation Therapy Approach International Journal of Radiation Oncology Biology Physics. 102. DOI: 10.1016/J.Ijrobp.2018.07.1588  0.525
2018 Colbert LE, Medrano AYD, Mikkelson MD, Previs R, Eifel PJ, Jhingran A, Ramondetta L, Futreal PA, Jazaeri A, Frumovitz M, Schmeler K, Hillman RT, Matthew G, Hutchinson DL, Ajami N, ... Stecklein SR, et al. Clonal Expansion of Antigen Specific T-Cells during Radiation Therapy for HPV Associated Cervical Cancers Is Regulated By the Vaginal Microbiome International Journal of Radiation Oncology Biology Physics. 102. DOI: 10.1016/J.Ijrobp.2018.06.145  0.308
2017 Ning MS, Ahobila V, Jhingran A, Stecklein SR, Frumovitz M, Schmeler KM, Eifel PJ, Klopp AH. Outcomes and patterns of relapse after definitive radiation therapy for oligometastatic cervical cancer. Gynecologic Oncology. PMID 29089122 DOI: 10.1016/J.Ygyno.2017.10.017  0.422
2017 Stecklein SR, Reddy JP, Wolfe AR, Lopez MS, Fouad TM, Debeb BG, Ueno NT, Brewster AM, Woodward WA. Lack of Breastfeeding History in Parous Women with Inflammatory Breast Cancer Predicts Poor Disease-Free Survival. Journal of Cancer. 8: 1726-1732. PMID 28819368 DOI: 10.7150/Jca.20095  0.678
2017 Rosso KJ, Tadros AB, Weiss A, Warneke CL, DeSnyder S, Kuerer H, Ueno NT, Stecklein SR, Woodward WA, Lucci A. Improved Locoregional Control in a Contemporary Cohort of Nonmetastatic Inflammatory Breast Cancer Patients Undergoing Surgery. Annals of Surgical Oncology. 24: 2981-2988. PMID 28766220 DOI: 10.1245/S10434-017-5952-X  0.688
2017 Stecklein SR, Park M, Liu DD, Valle JJ, Caudle AS, Mittendorf EA, Barcenas CH, Woodward WA, Valero V, Shaitelman SF. Impact of Regional Nodal Irradiation After Neoadjuvant Chemotherapy in Breast Cancer Patients With Cytologically Confirmed Axillary Lymph Node Metastases International Journal of Radiation Oncology Biology Physics. 99. DOI: 10.1016/J.Ijrobp.2017.06.704  0.623
2016 Stecklein SR, Jhingran A, Burzawa J, Ramalingam P, Klopp AH, Eifel PJ, Frumovitz M. Patterns of recurrence and survival in neuroendocrine cervical cancer. Gynecologic Oncology. 143: 552-557. PMID 27645621 DOI: 10.1016/J.Ygyno.2016.09.011  0.388
2016 Stecklein SR, Shen X, Mitchell MP. Post-Mastectomy Radiation Therapy for Invasive Lobular Carcinoma: A Comparative Utilization and Outcomes Study. Clinical Breast Cancer. PMID 26943990 DOI: 10.1016/J.Clbc.2016.02.001  0.444
2016 Stecklein S, Shaitelman S. DBCG-IMN: A Population-Based Cohort Study on the Effect of Internal Mammary Node Irradiation in Early Node-Positive Breast Cancer Breast Diseases: a Year Book Quarterly. 27: 211-213. DOI: 10.1016/J.BREASTDIS.2016.07.018  0.369
2015 Kumaraswamy E, Wendt KL, Augustine LA, Stecklein SR, Sibala EC, Li D, Gunewardena S, Jensen RA. BRCA1 regulation of epidermal growth factor receptor (EGFR) expression in human breast cancer cells involves microRNA-146a and is critical for its tumor suppressor function. Oncogene. 34: 4333-46. PMID 25417703 DOI: 10.1038/Onc.2014.363  0.602
2015 Stecklein SR, Reddy J, Wolfe A, Lopez MS, Fouad TM, Debeb BG, Brewster AM, Ueno NT, Woodward WA. Lack of Breastfeeding History in Parous Women With Inflammatory Breast Cancer Predicts Locoregional Recurrence and Distant Metastasis International Journal of Radiation Oncology Biology Physics. 93. DOI: 10.1016/J.Ijrobp.2015.07.563  0.596
2014 Stecklein SR, Sharma P. Tumor homologous recombination deficiency assays: another step closer to clinical application? Breast Cancer Research : Bcr. 16: 409. PMID 25928813 DOI: 10.1186/S13058-014-0409-7  0.515
2014 Sharma P, Stecklein SR, Kimler BF, Sethi G, Petroff BK, Phillips TA, Tawfik OW, Godwin AK, Jensen RA. The prognostic value of BRCA1 promoter methylation in early stage triple negative breast cancer. Journal of Cancer Therapeutics & Research. 3: 1-11. PMID 25177489 DOI: 10.7243/2049-7962-3-2  0.597
2014 Sharma P, Klemp JR, Kimler BF, Mahnken JD, Geier LJ, Khan QJ, Elia M, Connor CS, McGinness MK, Mammen JM, Wagner JL, Ward C, Ranallo L, Knight CJ, Stecklein SR, et al. Germline BRCA mutation evaluation in a prospective triple-negative breast cancer registry: implications for hereditary breast and/or ovarian cancer syndrome testing. Breast Cancer Research and Treatment. 145: 707-14. PMID 24807107 DOI: 10.1007/S10549-014-2980-0  0.616
2014 Paul A, Gunewardena S, Stecklein SR, Saha B, Parelkar N, Danley M, Rajendran G, Home P, Ray S, Jokar I, Vielhauer GA, Jensen RA, Tawfik O, Paul S. PKCλ/ι signaling promotes triple-negative breast cancer growth and metastasis. Cell Death and Differentiation. 21: 1469-81. PMID 24786829 DOI: 10.1038/Cdd.2014.62  0.7
2014 Sharma P, Stecklein SR, Kimler BF, Khan QJ, Connor CS, McGinness M, Mammen J, Wagner JL, Jensen RA, Godwin AK, Fabian CJ. Efficacy of neoadjuvant carboplatin/docetaxel chemotherapy in sporadic and BRCA-associated triple-negative breast cancer (TNBC). Journal of Clinical Oncology. 32: 1022-1022. DOI: 10.1200/Jco.2014.32.15_Suppl.1022  0.672
2014 Stecklein SR, Jensen RA. Breast cancer stem cells Stem Cells and Human Diseases. 451-465. DOI: 10.1007/978-94-007-2801-1_20  0.621
2013 Stecklein S, Elsarraj H, Valdez K, Paul A, Behbod F. Breast cancer invasion and metastasis Experimental Metastasis: Modeling and Analysis. 27-56. DOI: 10.1007/978-94-007-7835-1_3  0.753
2012 Stecklein SR, Kumaraswamy E, Behbod F, Wang W, Chaguturu V, Harlan-Williams LM, Jensen RA. BRCA1 and HSP90 cooperate in homologous and non-homologous DNA double-strand-break repair and G2/M checkpoint activation. Proceedings of the National Academy of Sciences of the United States of America. 109: 13650-5. PMID 22869732 DOI: 10.1073/Pnas.1203326109  0.746
2012 Stecklein SR, Jensen RA. Identifying and exploiting defects in the Fanconi anemia/BRCA pathway in oncology. Translational Research : the Journal of Laboratory and Clinical Medicine. 160: 178-97. PMID 22683426 DOI: 10.1016/J.Trsl.2012.01.022  0.614
2012 Elsarraj HS, Stecklein SR, Valdez K, Behbod F. Emerging functions of microRNA-146a/b in development and breast cancer: microRNA-146a/b in development and breast cancer. Journal of Mammary Gland Biology and Neoplasia. 17: 79-87. PMID 22350993 DOI: 10.1007/S10911-012-9240-X  0.64
2012 Stecklein SR, Jensen RA, Pal A. Genetic and epigenetic signatures of breast cancer subtypes. Frontiers in Bioscience (Elite Edition). 4: 934-49. PMID 22201926  0.644
2012 Bhalla K, Rao R, Sharma P, Gupta SD, Chauhan L, Stecklein S, Fiskus W. Abstract S3-7: Treatment with Histone Deacetylase Inhibitors Creates ‘BRCAness’ and Sensitizes Human Triple Negative Breast Cancer Cells to PARP Inhibitors and Cisplatin Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-S3-7  0.471
2012 Sharma P, Stecklein S, Kimler B, Klemp J, Khan Q, Fabian C, Tawfik O, Connor C, McGinness M, Mammen J, Jensen R. Abstract PD09-02: BRCA1 insufficiency is predictive of superior survival in patients with triple negative breast cancer treated with platinum based chemotherapy Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-Pd09-02  0.663
2012 Zhang X, Stecklein S, Behbod F, Cohen M. A New Mechanism of Action for Withaferin a in Breast Cancer: Induction of Proteasomal-degradation of Notch1 and Notch3 Proteins Journal of Surgical Research. 172: 342. DOI: 10.1016/J.JSS.2011.11.724  0.718
2011 Sharma P, Kimler BF, Park YA, Stecklein SR, Khan QJ, Petroff BK, Tawfik OW, Jensen RA. Association of BRCA1 promoter methylation in triple-negative breast cancer (TNBC) with resistance to standard anthracyline-based adjuvant chemotherapy. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 1123. PMID 28021523 DOI: 10.1200/Jco.2011.29.15_Suppl.1123  0.636
2011 Kumaraswamy E, Stecklein SR, Augustine LA, Jensen RA. Abstract 1188: BRCA1 regulates EGFR expression through microRNAs Cancer Research. 71: 1188-1188. DOI: 10.1158/1538-7445.Am2011-1188  0.606
2011 Jensen RA, Harlan-Williams LM, Wang W, Stecklein SR. Basic cancer biology and immunology Principles and Practice of Fertility Preservation. 35-48. DOI: 10.1017/CBO9780511921896.007  0.537
2010 Harlan-Williams LM, Overton JA, Stecklein SR, Wang W, Jensen RA. Abstract 757: Identification and characterization of small molecule activators of BRCA1 expression Cancer Research. 70: 757-757. DOI: 10.1158/1538-7445.Am10-757  0.678
2010 Stecklein SR, Harlan-Williams LM, Wang W, Eskew JD, Chaguturu V, Jensen RA. Abstract 1391: Inhibition of Hsp90 induces BRCA1 degradation and hypersensitivity to ionizing radiation Cancer Research. 70: 1391-1391. DOI: 10.1158/1538-7445.Am10-1391  0.655
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