Year |
Citation |
Score |
2023 |
Münch C, Kirstein J. Protein quality control: from molecular mechanisms to therapeutic intervention-EMBO workshop, May 21-26 2023, Srebreno, Croatia. Cell Stress & Chaperones. PMID 37731161 DOI: 10.1007/s12192-023-01383-4 |
0.352 |
|
2021 |
Pras A, Houben B, Aprile FA, Seinstra R, Gallardo R, Janssen L, Hogewerf W, Gallrein C, De Vleeschouwer M, Mata-Cabana A, Koopman M, Stroo E, de Vries M, Louise Edwards S, Kirstein J, et al. The cellular modifier MOAG-4/SERF drives amyloid formation through charge complementation. The Embo Journal. e107568. PMID 34617299 DOI: 10.15252/embj.2020107568 |
0.638 |
|
2021 |
Ayala Mariscal SM, Kirstein J. J-domain proteins interaction with neurodegenerative disease-related proteins. Experimental Cell Research. 399: 112491. PMID 33460589 DOI: 10.1016/j.yexcr.2021.112491 |
0.431 |
|
2020 |
Gallrein C, Iburg M, Michelberger T, Koçak A, Puchkov D, Liu F, Ayala Mariscal SM, Nayak T, Kaminski Schierle GS, Kirstein J. Novel Amyloid-beta pathology C. elegans model reveals distinct neurons as seeds of pathogenicity. Progress in Neurobiology. 101907. PMID 32926945 DOI: 10.1016/J.Pneurobio.2020.101907 |
0.327 |
|
2020 |
Haenig C, Atias N, Taylor AK, Mazza A, Schaefer MH, Russ J, Riechers SP, Jain S, Coughlin M, Fontaine JF, Freibaum BD, Brusendorf L, Zenkner M, Porras P, Stroedicke M, ... ... Kirstein J, et al. Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains. Cell Reports. 32: 108050. PMID 32814053 DOI: 10.1016/J.Celrep.2020.108050 |
0.528 |
|
2020 |
Pigazzini ML, Kirstein J. In Vivo Quantification of Protein Turnover in Aging C. Elegans using Photoconvertible Dendra2. Journal of Visualized Experiments : Jove. PMID 32597843 DOI: 10.3791/61196 |
0.48 |
|
2020 |
Claes F, Rudyak S, Laird AS, Louros N, Beerten J, Debulpaep M, Michiels E, van der Kant R, Van Durme J, De Baets G, Houben B, Ramakers M, Yuan K, Gwee SSL, Hernandez S, ... ... Kirstein J, et al. Exposure of a cryptic Hsp70 binding site determines the cytotoxicity of the ALS-associated SOD1-mutant A4V. Protein Engineering, Design & Selection : Peds. PMID 32399571 DOI: 10.1093/Protein/Gzaa008 |
0.412 |
|
2020 |
Pigazzini ML, Gallrein C, Iburg M, Kaminski Schierle G, Kirstein J. Characterization of Amyloid Structures in Aging C. Elegans Using Fluorescence Lifetime Imaging. Journal of Visualized Experiments : Jove. PMID 32281971 DOI: 10.3791/61004 |
0.454 |
|
2020 |
Iburg M, Puchkov D, Rosas-Brugada IU, Bergemann L, Rieprecht U, Kirstein J. The noncanonical small heat shock protein HSP-17 from is a selective protein aggregase. The Journal of Biological Chemistry. 295: 3064-3079. PMID 32001616 DOI: 10.1074/Jbc.Ra119.011185 |
0.549 |
|
2020 |
Sandhof CA, Hoppe SO, Druffel-Augustin S, Gallrein C, Kirstein J, Voisine C, Nussbaum-Krammer C. Reducing INS-IGF1 signaling protects against non-cell autonomous vesicle rupture caused by SNCA spreading. Autophagy. 16: 878-899. PMID 31354022 DOI: 10.1080/15548627.2019.1643657 |
0.395 |
|
2019 |
Feleciano DR, Juenemann K, Iburg M, Brás IC, Holmberg CI, Kirstein J. Crosstalk Between Chaperone-Mediated Protein Disaggregation and Proteolytic Pathways in Aging and Disease. Frontiers in Aging Neuroscience. 11: 9. PMID 30760997 DOI: 10.3389/Fnagi.2019.00009 |
0.587 |
|
2019 |
Kreis P, Gallrein C, Rojas-Puente E, Mack TGA, Kroon C, Dinkel V, Willmes C, Murk K, Tom-Dieck S, Schuman EM, Kirstein J, Eickholt BJ. ATM phosphorylation of the actin-binding protein drebrin controls oxidation stress-resistance in mammalian neurons and C. elegans. Nature Communications. 10: 486. PMID 30700723 DOI: 10.1038/S41467-019-08420-W |
0.392 |
|
2018 |
Kampinga HH, Andreasson C, Barducci A, Cheetham ME, Cyr D, Emanuelsson C, Genevaux P, Gestwicki JE, Goloubinoff P, Huerta-Cepas J, Kirstein J, Liberek K, Mayer MP, Nagata K, Nillegoda NB, et al. Function, evolution, and structure of J-domain proteins. Cell Stress & Chaperones. PMID 30478692 DOI: 10.1007/S12192-018-0948-4 |
0.454 |
|
2018 |
Juenemann K, Jansen AHP, van Riel L, Merkx R, Mulder MPC, An H, Statsyuk A, Kirstein J, Ovaa H, Reits EA. Dynamic recruitment of ubiquitin to mutant huntingtin inclusion bodies. Scientific Reports. 8: 1405. PMID 29362455 DOI: 10.1038/S41598-018-19538-0 |
0.398 |
|
2017 |
Scior A, Buntru A, Arnsburg K, Ast A, Iburg M, Juenemann K, Pigazzini ML, Mlody B, Puchkov D, Priller J, Wanker EE, Prigione A, Kirstein J. Complete suppression of Htt fibrilization and disaggregation of Htt fibrils by a trimeric chaperone complex. The Embo Journal. PMID 29212816 DOI: 10.15252/Embj.201797212 |
0.467 |
|
2017 |
Kirstein J, Arnsburg K, Scior A, Szlachcic A, Guilbride DL, Morimoto RI, Bukau B, Nillegoda NB. In vivo properties of the disaggregase function of J-proteins and Hsc70 in Caenorhabditis elegans stress and aging. Aging Cell. PMID 29024389 DOI: 10.1111/Acel.12686 |
0.662 |
|
2017 |
Lechler MC, Crawford ED, Groh N, Widmaier K, Jung R, Kirstein J, Trinidad JC, Burlingame AL, David DC. Reduced Insulin/IGF-1 Signaling Restores the Dynamic Properties of Key Stress Granule Proteins during Aging. Cell Reports. 18: 454-467. PMID 28076789 DOI: 10.1016/J.Celrep.2016.12.033 |
0.452 |
|
2016 |
Scior A, Juenemann K, Kirstein J. Cellular strategies to cope with protein aggregation. Essays in Biochemistry. 60: 153-161. PMID 27744331 DOI: 10.1042/Ebc20160002 |
0.557 |
|
2016 |
Feleciano DR, Arnsburg K, Kirstein J. Interplay between redox and protein homeostasis. Worm. 5: e1170273. PMID 27386166 DOI: 10.1080/21624054.2016.1170273 |
0.402 |
|
2016 |
Feleciano DR, Kirstein J. Collapse of redox homeostasis during aging and stress. Molecular & Cellular Oncology. 3: e1091060. PMID 27308612 DOI: 10.1080/23723556.2015.1091060 |
0.405 |
|
2015 |
Nillegoda NB, Kirstein J, Szlachcic A, Berynskyy M, Stank A, Stengel F, Arnsburg K, Gao X, Scior A, Aebersold R, Guilbride DL, Wade RC, Morimoto RI, Mayer MP, Bukau B. Crucial HSP70 co-chaperone complex unlocks metazoan protein disaggregation. Nature. 524: 247-51. PMID 26245380 DOI: 10.1038/Nature14884 |
0.662 |
|
2015 |
Kirstein J, Morito D, Kakihana T, Sugihara M, Minnen A, Hipp MS, Nussbaum-Krammer C, Kasturi P, Hartl FU, Nagata K, Morimoto RI. Proteotoxic stress and ageing triggers the loss of redox homeostasis across cellular compartments. The Embo Journal. 34: 2334-49. PMID 26228940 DOI: 10.15252/Embj.201591711 |
0.555 |
|
2010 |
Wolf D, Kalamorz F, Wecke T, Juszczak A, Mäder U, Homuth G, Jordan S, Kirstein J, Hoppert M, Voigt B, Hecker M, Mascher T. In-depth profiling of the LiaR response of Bacillus subtilis. Journal of Bacteriology. 192: 4680-93. PMID 20639339 DOI: 10.1128/Jb.00543-10 |
0.429 |
|
2009 |
Kirstein J, Hoffmann A, Lilie H, Schmidt R, Rübsamen-Waigmann H, Brötz-Oesterhelt H, Mogk A, Turgay K. The antibiotic ADEP reprogrammes ClpP, switching it from a regulated to an uncontrolled protease. Embo Molecular Medicine. 1: 37-49. PMID 20049702 DOI: 10.1002/Emmm.200900002 |
0.452 |
|
2009 |
Kirstein J, Molière N, Dougan DA, Turgay K. Adapting the machine: Adaptor proteins for Hsp100/Clp and AAA+ proteases Nature Reviews Microbiology. 7: 589-599. PMID 19609260 DOI: 10.1038/Nrmicro2185 |
0.527 |
|
2008 |
Kirstein J, Strahl H, Molière N, Hamoen LW, Turgay K. Localization of general and regulatory proteolysis in Bacillus subtilis cells. Molecular Microbiology. 70: 682-94. PMID 18786145 DOI: 10.1111/J.1365-2958.2008.06438.X |
0.549 |
|
2008 |
Haslberger T, Zdanowicz A, Brand I, Kirstein J, Turgay K, Mogk A, Bukau B. Protein disaggregation by the AAA+ chaperone ClpB involves partial threading of looped polypeptide segments. Nature Structural & Molecular Biology. 15: 641-50. PMID 18488042 DOI: 10.1038/Nsmb.1425 |
0.501 |
|
2008 |
Erbse AH, Wagner JN, Truscott KN, Spall SK, Kirstein J, Zeth K, Turgay K, Mogk A, Bukau B, Dougan DA. Conserved residues in the N-domain of the AAA+ chaperone ClpA regulate substrate recognition and unfolding. The Febs Journal. 275: 1400-10. PMID 18279386 DOI: 10.1111/J.1742-4658.2008.06304.X |
0.368 |
|
2007 |
Kirstein J, Dougan DA, Gerth U, Hecker M, Turgay K. The tyrosine kinase McsB is a regulated adaptor protein for ClpCP Embo Journal. 26: 2061-2070. PMID 17380125 DOI: 10.1038/Sj.Emboj.7601655 |
0.52 |
|
2006 |
Kirstein J, Schlothauer T, Dougan DA, Lilie H, Tischendorf G, Mogk A, Bukau B, Turgay K. Adaptor protein controlled oligomerization activates the AAA+ protein ClpC. The Embo Journal. 25: 1481-91. PMID 16525504 DOI: 10.1038/Sj.Emboj.7601042 |
0.551 |
|
2006 |
Andersson FI, Blakytny R, Kirstein J, Turgay K, Bukau B, Mogk A, Clarke AK. Cyanobacterial ClpC/HSP100 protein displays intrinsic chaperone activity. The Journal of Biological Chemistry. 281: 5468-75. PMID 16361263 DOI: 10.1074/Jbc.M509661200 |
0.574 |
|
2005 |
Kirstein J, Zühlke D, Gerth U, Turgay K, Hecker M. A tyrosine kinase and its activator control the activity of the CtsR heat shock repressor in B. subtilis. The Embo Journal. 24: 3435-45. PMID 16163393 DOI: 10.1038/Sj.Emboj.7600780 |
0.337 |
|
2004 |
Gerth U, Kirstein J, Mostertz J, Waldminghaus T, Miethke M, Kock H, Hecker M. Fine-tuning in regulation of Clp protein content in Bacillus subtilis. Journal of Bacteriology. 186: 179-91. PMID 14679237 DOI: 10.1128/Jb.186.1.179-191.2004 |
0.532 |
|
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