Mathieu Laplante - Publications

Affiliations: 
Laval University, Ville de Québec, Québec, Canada 

63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Kumar A, Laborit Labrada B, Lavallée-Bourget MH, Forest MP, Schwab M, Bellmann K, Houde V, Beauchemin N, Laplante M, Marette A. Regulation of PPARγ2 Stability and Activity by SHP-1. Molecular and Cellular Biology. 1-12. PMID 38828991 DOI: 10.1080/10985549.2024.2354959  0.303
2024 Samson N, Bosoi CR, Roy C, Turcotte L, Tribouillard L, Mouchiroud M, Berthiaume L, Trottier J, Silva HCG, Guerbette T, Plata-Gómez AB, Besse-Patin A, Montoni A, Ilacqua N, Lamothe J, ... ... Laplante M, et al. HSDL2 links nutritional cues to bile acid and cholesterol homeostasis. Science Advances. 10: eadk9681. PMID 38820148 DOI: 10.1126/sciadv.adk9681  0.626
2022 Colas C, Mouchiroud M, Al Dow M, Kolnohuz A, Gélinas Y, Caron A, Laplante M. DEPTOR loss impairs brown adipocyte development in vitro but has limited impacts in mice. Molecular Metabolism. 67: 101660. PMID 36535626 DOI: 10.1016/j.molmet.2022.101660  0.642
2022 Vilela VR, Samson N, Nachbar R, Perazza LR, Lachance G, Rokatoarivelo V, Centano-Baez C, Zancan P, Sola-Penna M, Bellmann K, Di Marzo V, Laplante M, Marette A. Adipocyte-specific Nos2 deletion improves insulin resistance and dyslipidemia through brown fat activation in diet-induced obese mice. Molecular Metabolism. 57: 101437. PMID 35033724 DOI: 10.1016/j.molmet.2022.101437  0.331
2022 Girard R, Tremblay S, Noll C, St-Jean S, Jones C, Gélinas Y, Maloum-Rami F, Perreault N, Laplante M, Carpentier AC, Boudreau F. The transcription factor hepatocyte nuclear factor 4A acts in the intestine to promote white adipose tissue energy storage. Nature Communications. 13: 224. PMID 35017517 DOI: 10.1038/s41467-021-27934-w  0.337
2021 Castro É, Vieira TS, Oliveira TE, Ortiz-Silva M, Andrade ML, Tomazelli CA, Peixoto AS, Sobrinho CR, Moreno MF, Gilio GR, Moreira RJ, Guimarães RC, Perandini LA, Chimin P, Reckziegel P, ... ... Laplante M, et al. Adipocyte-specific mTORC2 deficiency impairs BAT and iWAT thermogenic capacity without affecting glucose uptake and energy expenditure in cold-acclimated mice. American Journal of Physiology. Endocrinology and Metabolism. 321: E592-E605. PMID 34541875 DOI: 10.1152/ajpendo.00587.2020  0.359
2021 de la Calle Arregui C, Plata-Gómez AB, Deleyto-Seldas N, García F, Ortega-Molina A, Abril-Garrido J, Rodriguez E, Nemazanyy I, Tribouillard L, de Martino A, Caleiras E, Campos-Olivas R, Mulero F, Laplante M, Muñoz J, et al. Limited survival and impaired hepatic fasting metabolism in mice with constitutive Rag GTPase signaling. Nature Communications. 12: 3660. PMID 34135321 DOI: 10.1038/s41467-021-23857-8  0.572
2020 Al Dow M, Silveira MAD, Poliquin A, Tribouillard L, Fournier É, Trébaol E, Secco B, Villot R, Tremblay F, Bilodeau S, Laplante M. CONTROL OF ADIPOGENIC COMMITMENT BY A STAT3-VSTM2A AXIS. American Journal of Physiology. Endocrinology and Metabolism. PMID 33196296 DOI: 10.1152/ajpendo.00314.2020  0.328
2020 Marcouiller F, Jochmans-Lemoine A, Ganouna G, Mouchiroud M, Laplante M, Marette A, Joseph V. Metabolic responses to intermittent hypoxia are regulated by sex and gonadal hormones in mice. The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05178  0.355
2019 Mouchiroud M, Camiré É, Aldow M, Caron A, Jubinville É, Turcotte L, Kaci I, Beaulieu MJ, Roy C, Labbé SM, Varin TV, Gélinas Y, Lamothe J, Trottier J, Mitchell PL, ... ... Laplante M, et al. The Hepatokine TSK does not affect brown fat thermogenic capacity, body weight gain, and glucose homeostasis. Molecular Metabolism. 30: 184-191. PMID 31767170 DOI: 10.1016/J.Molmet.2019.09.014  0.64
2019 Mouchiroud M, Camiré É, Aldow M, Caron A, Jubinville É, Turcotte L, Kaci I, Beaulieu MJ, Roy C, Labbé SM, Varin TV, Gélinas Y, Lamothe J, Trottier J, Mitchell PL, ... ... Laplante M, et al. The hepatokine Tsukushi is released in response to NAFLD and impacts cholesterol homeostasis. Jci Insight. 4. PMID 31391339 DOI: 10.1172/Jci.Insight.129492  0.582
2019 Besse-Patin A, Jeromson S, Levesque-Damphousse P, Secco B, Laplante M, Estall JL. PGC1A regulates the IRS1:IRS2 ratio during fasting to influence hepatic metabolism downstream of insulin. Proceedings of the National Academy of Sciences of the United States of America. PMID 30770439 DOI: 10.1073/pnas.1815150116  0.339
2018 Wedel J, Bruneau S, Liu K, Kong SW, Sage PT, Sabatini DM, Laplante M, Briscoe DM. Deptor modulates activation responses in CD4 T cells and enhances immunoregulation following transplantation. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 29969188 DOI: 10.1111/Ajt.14995  0.515
2018 Caron A, Briscoe DM, Richard D, Laplante M. DEPTOR at the Nexus of Cancer, Metabolism, and Immunity. Physiological Reviews. 98: 1765-1803. PMID 29897294 DOI: 10.1152/Physrev.00064.2017  0.682
2018 Wilson AM, Shao Z, Grenier V, Mawambo G, Daudelin JF, Dejda A, Pilon F, Popovic N, Boulet S, Parinot C, Oubaha M, Labrecque N, de Guire V, Laplante M, Lettre G, et al. Neuropilin-1 expression in adipose tissue macrophages protects against obesity and metabolic syndrome. Science Immunology. 3. PMID 29549139 DOI: 10.1126/Sciimmunol.Aan4626  0.487
2018 Carter S, Miard S, Caron A, Sallé-Lefort S, St-Pierre P, Anhê FF, Lavoie-Charland E, Blais-Lecours P, Drolet MC, Lefebvre JS, Lacombe J, Deshaies Y, Couet J, Laplante M, Ferron M, et al. Loss of OcaB Prevents Age-Induced Fat Accretion and Insulin Resistance by Altering B Lymphocyte Transition and Promoting Energy Expenditure. Diabetes. PMID 29496744 DOI: 10.2337/Db17-0558  0.761
2017 Chechi K, Voisine P, Mathieu P, Laplante M, Bonnet S, Picard F, Joubert P, Richard D. Functional characterization of the Ucp1-associated oxidative phenotype of human epicardial adipose tissue. Scientific Reports. 7: 15566. PMID 29138472 DOI: 10.1038/S41598-017-15501-7  0.612
2017 Caron A, Mouchiroud M, Gautier N, Labbé SM, Villot R, Turcotte L, Secco B, Lamoureux G, Shum M, Gélinas Y, Marette A, Richard D, Sabatini DM, Laplante M. Loss of hepatic DEPTOR alters the metabolic transition to fasting. Molecular Metabolism. 6: 447-458. PMID 28462079 DOI: 10.1016/J.Molmet.2017.02.005  0.748
2017 Secco B, Camiré É, Brière MA, Caron A, Billong A, Gélinas Y, Lemay AM, Tharp KM, Lee PL, Gobeil S, Guimond JV, Patey N, Guertin DA, Stahl A, Haddad É, ... ... Laplante M, et al. Amplification of Adipogenic Commitment by VSTM2A. Cell Reports. 18: 93-106. PMID 28052263 DOI: 10.1016/J.Celrep.2016.12.015  0.749
2016 Labbé SM, Mouchiroud M, Caron A, Secco B, Freinkman E, Lamoureux G, Gélinas Y, Lecomte R, Bossé Y, Chimin P, Festuccia WT, Richard D, Laplante M. mTORC1 is Required for Brown Adipose Tissue Recruitment and Metabolic Adaptation to Cold. Scientific Reports. 6: 37223. PMID 27876792 DOI: 10.1038/Srep37223  0.736
2016 Carbonneau M, M Gagné L, Lalonde ME, Germain MA, Motorina A, Guiot MC, Secco B, Vincent EE, Tumber A, Hulea L, Bergeman J, Oppermann U, Jones RG, Laplante M, Topisirovic I, et al. The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway. Nature Communications. 7: 12700. PMID 27624942 DOI: 10.1038/Ncomms12700  0.36
2016 Labbé SM, Caron A, Chechi K, Laplante M, Lecomte R, Richard D. Metabolic activity of brown, "beige" and white adipose tissues in response to chronic adrenergic stimulation in male mice. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00545.2015. PMID 27143559 DOI: 10.1152/Ajpendo.00545.2015  0.733
2016 Caron A, Labbé SM, Mouchiroud M, Huard R, Richard D, Laplante M. DEPTOR IN POMC NEURONS AFFECTS LIVER METABOLISM BUT IS DISPENSABLE FOR THE REGULATION OF ENERGY BALANCE. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00549.2015. PMID 27097662 DOI: 10.1152/Ajpregu.00549.2015  0.727
2016 Caron A, Labbé SM, Lanfray D, Blanchard PG, Villot R, Roy C, Sabatini DM, Richard D, Laplante M. Mediobasal hypothalamic overexpression of DEPTOR protects against high-fat diet-induced obesity. Molecular Metabolism. 5: 102-12. PMID 26909318 DOI: 10.1016/J.Molmet.2015.11.005  0.769
2016 Lanfray D, Caron A, Roy MC, Laplante M, Morin F, Leprince J, Tonon MC, Richard D. Involvement of the Acyl-CoA binding domain containing 7 in the control of food intake and energy expenditure in mice. Elife. 5. PMID 26880548 DOI: 10.7554/Elife.11742  0.695
2016 Lanfray D, Caron A, Roy M, Laplante M, Morin F, Leprince J, Tonon M, Richard D. Author response: Involvement of the Acyl-CoA binding domain containing 7 in the control of food intake and energy expenditure in mice Elife. DOI: 10.7554/Elife.11742.036  0.661
2015 Caron A, Richard D, Laplante M. The Roles of mTOR Complexes in Lipid Metabolism. Annual Review of Nutrition. 35: 321-48. PMID 26185979 DOI: 10.1146/Annurev-Nutr-071714-034355  0.729
2015 Labbé SM, Caron A, Bakan I, Laplante M, Carpentier AC, Lecomte R, Richard D. In vivo measurement of energy substrate contribution to cold-induced brown adipose tissue thermogenesis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 2046-58. PMID 25681456 DOI: 10.1096/Fj.14-266247  0.709
2015 Caron A, Baraboi ED, Laplante M, Richard D. DEP domain-containing mTOR-interacting protein in the rat brain: distribution of expression and potential implication. The Journal of Comparative Neurology. 523: 93-107. PMID 25159114 DOI: 10.1002/Cne.23668  0.699
2015 Caron A, Labbé SM, Lanfray D, Blanchard PG, Villot R, Roy C, Sabatini DM, Richard D, Laplante M. Mediobasal hypothalamic overexpression of DEPTOR protects against high-fat diet-induced obesity Molecular Metabolism. DOI: 10.1016/j.molmet.2015.11.005  0.72
2014 Sood A, Jeyaraju DV, Prudent J, Caron A, Lemieux P, McBride HM, Laplante M, Tóth K, Pellegrini L. A Mitofusin-2-dependent inactivating cleavage of Opa1 links changes in mitochondria cristae and ER contacts in the postprandial liver. Proceedings of the National Academy of Sciences of the United States of America. 111: 16017-22. PMID 25352671 DOI: 10.1073/Pnas.1408061111  0.613
2014 Chabot F, Caron A, Laplante M, St-Pierre DH. Interrelationships between ghrelin, insulin and glucose homeostasis: Physiological relevance. World Journal of Diabetes. 5: 328-41. PMID 24936254 DOI: 10.4239/Wjd.V5.I3.328  0.608
2014 Festuccia WT, Pouliot P, Bakan I, Sabatini DM, Laplante M. Myeloid-specific Rictor deletion induces M1 macrophage polarization and potentiates in vivo pro-inflammatory response to lipopolysaccharide. Plos One. 9: e95432. PMID 24740015 DOI: 10.1371/Journal.Pone.0095432  0.577
2013 Birsoy K, Festuccia WT, Laplante M. A comparative perspective on lipid storage in animals. Journal of Cell Science. 126: 1541-52. PMID 23658371 DOI: 10.1242/Jcs.104992  0.664
2013 Laplante M, Sabatini DM. Regulation of mTORC1 and its impact on gene expression at a glance. Journal of Cell Science. 126: 1713-9. PMID 23641065 DOI: 10.1242/Jcs.125773  0.6
2012 Laplante M, Horvat S, Festuccia WT, Birsoy K, Prevorsek Z, Efeyan A, Sabatini DM. DEPTOR cell-autonomously promotes adipogenesis, and its expression is associated with obesity. Cell Metabolism. 16: 202-12. PMID 22883231 DOI: 10.1016/J.Cmet.2012.07.008  0.744
2012 Laplante M, Sabatini DM. mTOR signaling in growth control and disease. Cell. 149: 274-93. PMID 22500797 DOI: 10.1016/J.Cell.2012.03.017  0.56
2012 Bakan I, Laplante M. Connecting mTORC1 signaling to SREBP-1 activation. Current Opinion in Lipidology. 23: 226-34. PMID 22449814 DOI: 10.1097/Mol.0B013E328352Dd03  0.449
2012 Li Z, Miard S, Laplante M, Sonenberg N, Picard F. Insulin stimulates IGFBP-2 expression in 3T3-L1 adipocytes through the PI3K/mTOR pathway. Molecular and Cellular Endocrinology. 358: 63-8. PMID 22410287 DOI: 10.1016/J.Mce.2012.02.022  0.43
2012 Laplante M, Sabatini DM. mTOR Signaling. Cold Spring Harbor Perspectives in Biology. 4. PMID 22129599 DOI: 10.1101/cshperspect.a011593  0.43
2010 Sengupta S, Peterson TR, Laplante M, Oh S, Sabatini DM. mTORC1 controls fasting-induced ketogenesis and its modulation by ageing. Nature. 468: 1100-4. PMID 21179166 DOI: 10.1038/Nature09584  0.602
2010 Laplante M, Sabatini DM. mTORC1 activates SREBP-1c and uncouples lipogenesis from gluconeogenesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 3281-2. PMID 20167806 DOI: 10.1073/Pnas.1000323107  0.582
2010 Berthiaume M, Laplante M, Festuccia WT, Berger JP, Thieringer R, Deshaies Y. Preliminary report: pharmacologic 11beta-hydroxysteroid dehydrogenase type 1 inhibition increases hepatic fat oxidation in vivo and expression of related genes in rats fed an obesogenic diet. Metabolism: Clinical and Experimental. 59: 114-7. PMID 19766266 DOI: 10.1016/J.Metabol.2009.07.015  0.594
2009 Laplante M, Sabatini DM. An emerging role of mTOR in lipid biosynthesis. Current Biology : Cb. 19: R1046-52. PMID 19948145 DOI: 10.1016/J.Cub.2009.09.058  0.59
2009 Laplante M, Sabatini DM. mTOR signaling at a glance. Journal of Cell Science. 122: 3589-94. PMID 19812304 DOI: 10.1242/Jcs.051011  0.554
2009 Peterson TR, Laplante M, Thoreen CC, Sancak Y, Kang SA, Kuehl WM, Gray NS, Sabatini DM. DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival. Cell. 137: 873-86. PMID 19446321 DOI: 10.1016/J.Cell.2009.03.046  0.556
2009 Festuccia WT, Laplante M, Brûlé S, Houde VP, Achouba A, Lachance D, Pedrosa ML, Silva ME, Guerra-Sá R, Couet J, Arsenault M, Marette A, Deshaies Y. Rosiglitazone-induced heart remodelling is associated with enhanced turnover of myofibrillar protein and mTOR activation. Journal of Molecular and Cellular Cardiology. 47: 85-95. PMID 19397913 DOI: 10.1016/J.Yjmcc.2009.04.011  0.612
2009 Berthiaume M, Laplante M, Festuccia WT, Berger JP, Thieringer R, Deshaies Y. Additive action of 11β-HSD1 inhibition and PPAR-γ agonism on hepatic steatosis and triglyceridemia in diet-induced obese rats. International Journal of Obesity. 33: 601-604. PMID 19223847 DOI: 10.1038/Ijo.2009.33  0.593
2009 Festuccia WT, Blanchard PG, Turcotte V, Laplante M, Sariahmetoglu M, Brindley DN, Richard D, Deshaies Y. The PPARgamma agonist rosiglitazone enhances rat brown adipose tissue lipogenesis from glucose without altering glucose uptake. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 296: R1327-35. PMID 19211718 DOI: 10.1152/Ajpregu.91012.2008  0.704
2009 Festuccia WT, Blanchard PG, Turcotte V, Laplante M, Sariahmetoglu M, Brindley DN, Deshaies Y. Depot-specific effects of the PPARgamma agonist rosiglitazone on adipose tissue glucose uptake and metabolism. Journal of Lipid Research. 50: 1185-94. PMID 19201733 DOI: 10.1194/Jlr.M800620-Jlr200  0.644
2009 Laplante M, Festuccia WT, Soucy G, Blanchard PG, Renaud A, Berger JP, Olivecrona G, Deshaies Y. Tissue-specific postprandial clearance is the major determinant of PPARgamma-induced triglyceride lowering in the rat. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 296: R57-66. PMID 18971352 DOI: 10.1152/Ajpregu.90552.2008  0.671
2008 Dallaire P, Bellmann K, Laplante M, Gélinas S, Centeno-Baez C, Penfornis P, Peyot ML, Latour MG, Lamontagne J, Trujillo ME, Scherer PE, Prentki M, Deshaies Y, Marette A. Obese mice lacking inducible nitric oxide synthase are sensitized to the metabolic actions of peroxisome proliferator-activated receptor-gamma agonism. Diabetes. 57: 1999-2011. PMID 18458147 DOI: 10.2337/Db08-0540  0.645
2008 Festuccia WT, Oztezcan S, Laplante M, Berthiaume M, Michel C, Dohgu S, Denis RG, Brito MN, Brito NA, Miller DS, Banks WA, Bartness TJ, Richard D, Deshaies Y. Peroxisome proliferator-activated receptor-gamma-mediated positive energy balance in the rat is associated with reduced sympathetic drive to adipose tissues and thyroid status. Endocrinology. 149: 2121-30. PMID 18218698 DOI: 10.1210/En.2007-1553  0.7
2007 Kim JY, van de Wall E, Laplante M, Azzara A, Trujillo ME, Hofmann SM, Schraw T, Durand JL, Li H, Li G, Jelicks LA, Mehler MF, Hui DY, Deshaies Y, Shulman GI, et al. Obesity-associated improvements in metabolic profile through expansion of adipose tissue. The Journal of Clinical Investigation. 117: 2621-37. PMID 17717599 DOI: 10.1172/Jci31021  0.668
2007 Cui W, Paglialunga S, Kalant D, Lu H, Roy C, Laplante M, Deshaies Y, Cianflone K. Acylation-stimulating protein/C5L2-neutralizing antibodies alter triglyceride metabolism in vitro and in vivo. American Journal of Physiology. Endocrinology and Metabolism. 293: E1482-91. PMID 17711993 DOI: 10.1152/Ajpendo.00565.2006  0.588
2007 Berthiaume M, Laplante M, Festuccia WT, Cianflone K, Turcotte LP, Joanisse DR, Olivecrona G, Thieringer R, Deshaies Y. 11beta-HSD1 inhibition improves triglyceridemia through reduced liver VLDL secretion and partitions lipids toward oxidative tissues. American Journal of Physiology. Endocrinology and Metabolism. 293: E1045-52. PMID 17666487 DOI: 10.1152/Ajpendo.00276.2007  0.649
2007 Berthiaume M, Laplante M, Tchernof A, Deshaies Y. Metabolic action of peroxisome proliferator-activated receptor gamma agonism in rats with exogenous hypercorticosteronemia. International Journal of Obesity (2005). 31: 1660-70. PMID 17579631 DOI: 10.1038/Sj.Ijo.0803668  0.591
2007 Berthiaume M, Laplante M, Festuccia W, Gélinas Y, Poulin S, Lalonde J, Joanisse DR, Thieringer R, Deshaies Y. Depot-specific modulation of rat intraabdominal adipose tissue lipid metabolism by pharmacological inhibition of 11beta-hydroxysteroid dehydrogenase type 1. Endocrinology. 148: 2391-7. PMID 17272400 DOI: 10.1210/En.2006-1199  0.657
2007 Laplante M, Festuccia WT, Soucy G, Gélinas Y, Lalonde J, Deshaies Y. Involvement of adipose tissues in the early hypolipidemic action of PPARγ agonism in the rat American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 292: R1408-R1417. PMID 17170230 DOI: 10.1152/Ajpregu.00761.2006  0.649
2006 Laplante M, Festuccia WT, Soucy G, Gélinas Y, Lalonde J, Berger JP, Deshaies Y. Mechanisms of the depot specificity of peroxisome proliferator-activated receptor γ action on adipose tissue metabolism Diabetes. 55: 2771-2778. PMID 17003342 DOI: 10.2337/Db06-0551  0.648
2006 Festuccia WT, Laplante M, Berthiaume M, Gélinas Y, Deshaies Y. PPARγ agonism increases rat adipose tissue lipolysis, expression of glyceride lipases, and the response of lipolysis to hormonal control Diabetologia. 49: 2427-2436. PMID 16906479 DOI: 10.1007/S00125-006-0336-Y  0.643
2004 Combs TP, Pajvani UB, Berg AH, Lin Y, Jelicks LA, Laplante M, Nawrocki AR, Rajala MW, Parlow AF, Cheeseboro L, Ding YY, Russell RG, Lindemann D, Hartley A, Baker GR, et al. A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity. Endocrinology. 145: 367-83. PMID 14576179 DOI: 10.1210/En.2003-1068  0.663
2003 Laplante M, Sell H, MacNaul KL, Richard D, Berger JP, Deshaies Y. PPAR-gamma activation mediates adipose depot-specific effects on gene expression and lipoprotein lipase activity: mechanisms for modulation of postprandial lipemia and differential adipose accretion. Diabetes. 52: 291-9. PMID 12540599 DOI: 10.2337/Diabetes.52.2.291  0.735
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