Paul Trayhurn - Publications

Affiliations: 
University of Buckingham 

144 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Trayhurn P. Brown Adipose Tissue: A Short Historical Perspective. Methods in Molecular Biology (Clifton, N.J.). 2448: 1-18. PMID 35167087 DOI: 10.1007/978-1-0716-2087-8_1  0.39
2022 Trayhurn P. Adipokines: inflammation and the pleiotropic role of white adipose tissue. The British Journal of Nutrition. 127: 161-164. PMID 35016740 DOI: 10.1017/S0007114521003962  0.389
2021 Trayhurn P. Through fat and thin - a journey with the adipose tissues. The Proceedings of the Nutrition Society. 80: 92-104. PMID 32046799 DOI: 10.1017/S002966512000004X  0.406
2020 Trayhurn P, Arch JRS. Is energy expenditure reduced in obese mice with mutations in the leptin/leptin receptor genes? Journal of Nutritional Science. 9: e23. PMID 32595967 DOI: 10.1017/jns.2020.19  0.301
2018 Trayhurn P. Brown Adipose Tissue-A Therapeutic Target in Obesity? Frontiers in Physiology. 9: 1672. PMID 30532712 DOI: 10.3389/fphys.2018.01672  0.334
2017 Trayhurn P. Origins and early development of the concept that brown adipose tissue thermogenesis is linked to energy balance and obesity. Biochimie. 134: 62-70. PMID 27621146 DOI: 10.1016/j.biochi.2016.09.007  0.414
2016 Trayhurn P. Recruiting Brown Adipose Tissue in Human Obesity. Diabetes. 65: 1158-60. PMID 27208185 DOI: 10.2337/dbi16-0002  0.349
2015 Trayhurn P, Alomar SY. Oxygen deprivation and the cellular response to hypoxia in adipocytes - perspectives on white and brown adipose tissues in obesity. Frontiers in Endocrinology. 6: 19. PMID 25745415 DOI: 10.3389/fendo.2015.00019  0.335
2014 Trayhurn P, Arch JR. New Physiological Aspects of Brown Adipose Tissue. Current Obesity Reports. 3: 414-21. PMID 26626918 DOI: 10.1007/s13679-014-0125-8  0.408
2014 Trayhurn P. Hypoxia and adipocyte physiology: implications for adipose tissue dysfunction in obesity. Annual Review of Nutrition. 34: 207-36. PMID 24819450 DOI: 10.1146/annurev-nutr-071812-161156  0.35
2013 Trayhurn P. Hypoxia and adipose tissue function and dysfunction in obesity. Physiological Reviews. 93: 1-21. PMID 23303904 DOI: 10.1152/Physrev.00017.2012  0.51
2011 Rooney K, Trayhurn P. Lactate and the GPR81 receptor in metabolic regulation: implications for adipose tissue function and fatty acid utilisation by muscle during exercise. The British Journal of Nutrition. 106: 1310-6. PMID 21902860 DOI: 10.1017/S0007114511004673  0.304
2011 Jensen J, Trayhurn P, Handberg A, Eckel J. Adipose tissue. Editorial. Archives of Physiology and Biochemistry. 117: 45-6. PMID 21457002 DOI: 10.3109/13813455.2010.547862  0.378
2011 Otway DT, Mäntele S, Bretschneider S, Wright J, Trayhurn P, Skene DJ, Robertson MD, Johnston JD. Rhythmic diurnal gene expression in human adipose tissue from individuals who are lean, overweight, and type 2 diabetic. Diabetes. 60: 1577-81. PMID 21411511 DOI: 10.2337/Db10-1098  0.391
2009 Trayhurn P. Obesity in the Inuit--adipose tissue and ischaemic heart disease. International Journal of Circumpolar Health. 68: 419-20. PMID 20044960  0.303
2009 Wood IS, de Heredia FP, Wang B, Trayhurn P. Cellular hypoxia and adipose tissue dysfunction in obesity. The Proceedings of the Nutrition Society. 68: 370-7. PMID 19698203 DOI: 10.1017/S0029665109990206  0.358
2009 Ding Q, Mracek T, Gonzalez-Muniesa P, Kos K, Wilding J, Trayhurn P, Bing C. Identification of macrophage inhibitory cytokine-1 in adipose tissue and its secretion as an adipokine by human adipocytes Endocrinology. 150: 1688-1696. PMID 19074584 DOI: 10.1210/en.2008-0952  0.304
2009 Leuwer M, Welters I, Marx G, Rushton A, Bao H, Hunter L, Trayhurn P. Endotoxaemia leads to major increases in inflammatory adipokine gene expression in white adipose tissue of mice. Pflugers Archiv : European Journal of Physiology. 457: 731-41. PMID 18677510 DOI: 10.1007/s00424-008-0564-8  0.355
2008 Trayhurn P, Wang B, Wood IS. Hypoxia and the endocrine and signalling role of white adipose tissue. Archives of Physiology and Biochemistry. 114: 267-76. PMID 18946787 DOI: 10.1080/13813450802306602   0.38
2008 Trayhurn P, Wang B, Wood IS. Hypoxia in adipose tissue: a basis for the dysregulation of tissue function in obesity? The British Journal of Nutrition. 100: 227-35. PMID 18397542 DOI: 10.1017/S0007114508971282  0.478
2007 Wang B, Wood IS, Trayhurn P. Dysregulation of the expression and secretion of inflammation-related adipokines by hypoxia in human adipocytes. Pflugers Archiv : European Journal of Physiology. 455: 479-92. PMID 17609976 DOI: 10.1007/S00424-007-0301-8  0.343
2006 Trayhurn P, Bing C, Wood IS. Adipose tissue and adipokines - Energy regulation from the human perspective Journal of Nutrition. 136: 1935S-1939S. PMID 16772463 DOI: 10.1093/Jn/136.7.1935S  0.492
2005 Trayhurn P, Wood IS. Signalling role of adipose tissue: adipokines and inflammation in obesity. Biochemical Society Transactions. 33: 1078-1081. PMID 16246049 DOI: 10.1042/Bst0331078  0.392
2005 Trayhurn P. Endocrine and signalling role of adipose tissue: new perspectives on fat. Acta Physiologica Scandinavica. 184: 285-293. PMID 16026420 DOI: 10.1111/J.1365-201X.2005.01468.X  0.421
2005 Trayhurn P. The biology of obesity. The Proceedings of the Nutrition Society. 64: 31-8. PMID 15877920 DOI: 10.1079/pns2004406  0.331
2005 Trayhurn P. Adipose tissue in obesity--an inflammatory issue. Endocrinology. 146: 1003-5. PMID 15713941 DOI: 10.1210/en.2004-1597  0.33
2004 Trayhurn P, Wood IS. Adipokines: inflammation and the pleiotropic role of white adipose tissue. The British Journal of Nutrition. 92: 347-55. PMID 15469638 DOI: 10.1079/Bjn20041213  0.46
2004 Bing C, Bao Y, Jenkins J, Sanders P, Manieri M, Cinti S, Tisdale MJ, Trayhurn P. Zinc-alpha2-glycoprotein, a lipid mobilizing factor, is expressed in adipocytes and is up-regulated in mice with cancer cachexia. Proceedings of the National Academy of Sciences of the United States of America. 101: 2500-5. PMID 14983038 DOI: 10.1073/Pnas.0308647100  0.462
2002 Bing C, Gomez-Ambrosi J, Zabalegui N, Williams G, Trayhurn P. Resistin and RELM-alpha gene expression in white adipose tissue of lactating mice. Biochemical and Biophysical Research Communications. 296: 458-62. PMID 12163041 DOI: 10.1016/s0006-291x(02)00846-x  0.352
2001 Haugen F, Jørgensen A, Drevon CA, Trayhurn P. Inhibition by insulin of resistin gene expression in 3T3-L1 adipocytes. Febs Letters. 507: 105-108. PMID 11682067 DOI: 10.1016/S0014-5793(01)02968-4  0.37
2001 Trayhurn P. Biology of leptin—its implications and consequences for the treatment of obesity International Journal of Obesity. 25. PMID 11466582 DOI: 10.1038/Sj.Ijo.0801692  0.396
2001 Rayner DV, Trayhurn P. Regulation of leptin production: sympathetic nervous system interactions. Journal of Molecular Medicine. 79: 8-20. PMID 11327106 DOI: 10.1007/S001090100198  0.509
2000 Trayhurn P, Duncan JS, Wood AM, Beattie JH. Regulation of metallothionein gene expression and secretion in rat adipocytes differentiated from preadipocytes in primary culture Hormone and Metabolic Research. 32: 542-547. PMID 11246822 DOI: 10.1055/S-2007-978683  0.354
2000 Trayhurn P, Duncan JS, Wood AM, Beattie JH. Metallothionein gene expression and secretion in white adipose tissue. American Journal of Physiology-Regulatory Integrative and Comparative Physiology. 279. PMID 11080101 DOI: 10.1152/Ajpregu.2000.279.6.R2329  0.451
2000 Beattie JH, Wood AM, Trayhurn P, Jasani B, Vincent A, McCormack G, West AK. Metallothionein is expressed in adipocytes of brown fat and is induced by catecholamines and zinc. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 278: R1082-9. PMID 10749798 DOI: 10.1152/Ajpregu.2000.278.4.R1082  0.401
2000 Berraondo B, Marti A, Duncan J, Trayhurn P, Martínez J. Up-regulation of muscle UCP2 gene expression by a new β3-adrenoceptor agonist, trecadrine, in obese (cafeteria) rodents, but down-regulation in lean animals International Journal of Obesity. 24: 156-163. PMID 10702765 DOI: 10.1038/Sj.Ijo.0801097  0.445
1999 Brogan RS, Mitchell SE, Trayhurn P, Smith MS. Suppression of leptin during lactation: Contribution of the suckling stimulus versus milk production Endocrinology. 140: 2621-2627. PMID 10342849 DOI: 10.1210/Endo.140.6.6802  0.358
1999 Trayhurn P, Hoggard N, Mercer J, Rayner DV. Leptin: fundamental aspects. International Journal of Obesity. 23: 22-28. PMID 10193858 DOI: 10.1038/Sj.Ijo.0800791  0.429
1998 Arch JRS, Stock MJ, Trayhurn P. Leptin resistance in obese humans: Does it exist and what does it mean? International Journal of Obesity. 22: 1159-1163. PMID 9877250 DOI: 10.1038/Sj.Ijo.0800779  0.363
1998 Finn D, Lomax MA, Trayhurn P. An immunohistochemical and in situ hybridisation study of the postnatal development of uncoupling protein-1 and uncoupling protein-1 mRNA in lamb perirenal adipose tissue. Cell and Tissue Research. 294: 461-6. PMID 9799463 DOI: 10.1007/S004410051197  0.458
1998 Trayhurn P, Hoggard N, Mercer J, Rayner DV. Hormonal and neuroendocrine regulation of energy balance--the role of leptin. Archives of Animal Nutrition. 51: 177-185. PMID 9672715 DOI: 10.1080/17450399809381917  0.436
1998 Rayner DV, Simón E, Duncan JS, Trayhurn P. Hyperleptinaemia in mice induced by administration of the tyrosine hydroxylase inhibitor α-methyl-p-tyrosine Febs Letters. 429: 395-398. PMID 9662456 DOI: 10.1016/S0014-5793(98)00642-5  0.397
1998 Beattie JH, Wood AM, Newman AM, Bremner I, Choo KH, Michalska AE, Duncan JS, Trayhurn P. Obesity and hyperleptinemia in metallothionein (-I and -II) null mice. Proceedings of the National Academy of Sciences of the United States of America. 95: 358-63. PMID 9419380 DOI: 10.1073/Pnas.95.1.358  0.412
1997 Hoggard N, Hunter L, Duncan JS, Williams LM, Trayhurn P, Mercer JG. Leptin and leptin receptor mRNA and protein expression in the murine fetus and placenta Proceedings of the National Academy of Sciences of the United States of America. 94: 11073-11078. PMID 9380761 DOI: 10.1073/Pnas.94.20.11073  0.385
1997 Bing C, Pickavance L, Wang Q, Frankish H, Trayhurn P, Williams G. Role of hypothalamic neuropeptide Y neurons in the defective thermogenic response to acute cold exposure in fatty Zucker rats. Neuroscience. 80: 277-284. PMID 9252238 DOI: 10.1016/S0306-4522(97)00121-8  0.402
1997 Rayner DV, Dalgliesh GD, Duncan JS, Hardie LJ, Hoggard N, Trayhurn P. Postnatal development of the ob gene system: elevated leptin levels in suckling fa/fa rats American Journal of Physiology-Regulatory Integrative and Comparative Physiology. 273. PMID 9249584 DOI: 10.1152/Ajpregu.1997.273.1.R446  0.381
1997 Hoggard N, Mercer JG, Rayner DV, Moar K, Trayhurn P, Williams LM. Localization of leptin receptor mRNA splice variants in murine peripheral tissues by RT-PCR and in situ hybridization. Biochemical and Biophysical Research Communications. 232: 383-387. PMID 9125186 DOI: 10.1006/Bbrc.1997.6245  0.369
1997 Mercer JG, Moar KM, Rayner DV, Trayhurn P, Hoggard N. Regulation of leptin receptor and NPY gene expression in hypothalamus of leptin-treated obese (ob/ob) and cold-exposed lean mice. Febs Letters. 402: 185-188. PMID 9037192 DOI: 10.1016/S0014-5793(96)01525-6  0.381
1997 Wang Q, Bing C, Al-Barazanji K, Mossakowaska DE, Wang X, McBay DL, Neville WA, Taddayon M, Pickavance L, Dryden S, Thomas MEA, McHale MT, Gloyer IS, Wilson S, Buckingham R, ... ... Trayhurn P, et al. Interactions Between Leptin and Hypothalamic Neuropeptide Y Neurons in the Control of Food Intake and Energy Homeostasis in the Rat Diabetes. 46: 335-341. PMID 9032086 DOI: 10.2337/Diab.46.3.335  0.326
1997 Mitchell SE, Rees WD, Hardie LJ, Hoggard N, Tadayyon M, Arch JRs, Trayhurn P. ob gene expression and secretion of leptin following differentiation of rat preadipocytes to adipocytes in primary culture Biochemical and Biophysical Research Communications. 230: 360-364. PMID 9016784 DOI: 10.1006/Bbrc.1996.5964  0.329
1997 Trayhurn P. Leptin ‐ the ‘new’ player in energy balance and obesity Nutrition Bulletin. 22: 7-14. DOI: 10.1111/J.1467-3010.1997.Tb00869.X  0.345
1996 Beattie JH, Black DJ, Wood AM, Trayhurn P. Cold-induced expression of the metallothionein-1 gene in brown adipose tissue of rats American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 270. PMID 8928928 DOI: 10.1152/Ajpregu.1996.270.5.R971  0.423
1996 Trayhurn P, Duncan JS, Rayner DV, Hardie LJ. Rapid inhibition of ob gene expression and circulating leptin levels in lean mice by the beta 3-adrenoceptor agonists BRL 35135A and ZD2079. Biochemical and Biophysical Research Communications. 228: 605-610. PMID 8920957 DOI: 10.1006/Bbrc.1996.1704  0.398
1996 Mercer J, Hoggard N, Williams L, Lawrence CB, Hannah LT, Morgan PJ, Trayhurn P. Coexpression of leptin receptor and preproneuropeptide Y mRNA in arcuate nucleus of mouse hypothalamus Journal of Neuroendocrinology. 8: 733-735. PMID 8910801 DOI: 10.1046/J.1365-2826.1996.05161.X  0.399
1996 Beattie JH, Shand D, Wood AM, Trayhurn P. Metallothionein gene expression in brown adipose tissue Biochemical Society Transactions. 24. PMID 8736817 DOI: 10.1042/Bst024159S  0.431
1996 Rubio-Aliaga I, Trayhurn P. Expression of the ob (obese) gene during lactation in mice. Biochemical Society Transactions. 24. PMID 8736815 DOI: 10.1042/Bst024157S  0.479
1996 Rayner DV, Trayhurn P. Ob (obese) gene expression in white adipose tissue of obese Zucker (fa/fa) rats. Biochemical Society Transactions. 24. PMID 8736814 DOI: 10.1042/Bst024156S  0.429
1996 Trayhurn P. Uncoupling protein in brown adipose tissue: molecular differentiation of the adipose tissues Biochemical Society Transactions. 24: 402-406. PMID 8736772 DOI: 10.1042/Bst0240402  0.486
1996 Hardie LJ, Rayner DV, Holmes S, Trayhurn P. Circulating Leptin Levels Are Modulated by Fasting, Cold Exposure and Insulin Administration in Lean but Not Zucker (fa/fa) Rats as Measured by ELISA Biochemical and Biophysical Research Communications. 223: 660-665. PMID 8687452 DOI: 10.1006/Bbrc.1996.0951  0.336
1996 Bing C, Pickavance L, Keith JS, Frankish HM, Wang Q, Trayhurn P, Williams G. Acute Cold Exposure Stimulates Uncoupling Protein Synthesis in Brown Adipose Tissue in Lean, but not Fatty Zucker Rats Clinical Science. 90: 16P-17P. DOI: 10.1042/Cs090016Pc  0.439
1995 Trayhurn P, Thomas MEA, Duncan JS, Rayner DV. Effects of fasting and refeeding on ob gene expression in white adipose tissue of lean and obese (ob/ob) mice Febs Letters. 368: 488-490. PMID 7635205 DOI: 10.1016/0014-5793(95)00719-P  0.479
1995 Trayhurn P, Duncan JS, Rayner DV. Acute cold-induced suppression of ob (obese) gene expression in white adipose tissue of mice: mediation by the sympathetic system Biochemical Journal. 311: 729-733. PMID 7487925 DOI: 10.1042/Bj3110729  0.477
1994 Nicol F, Lefranc H, Arthur JR, Trayhurn P. Characterization and postnatal development of 5'-deiodinase activity in goat perirenal fat. The American Journal of Physiology. 267: R144-9. PMID 8048616 DOI: 10.1152/Ajpregu.1994.267.1.R144  0.428
1994 Trayhurn P, Duncan JS, Nestor A, Thomas ME, Rayner DV. Chemiluminescent detection of mRNAs on northern blots with digoxigenin end-labeled oligonucleotides. Analytical Biochemistry. 222: 224-30. PMID 7856853 DOI: 10.1006/Abio.1994.1477  0.336
1993 McCarthy HD, Kilpatrick AP, Trayhurn P, Williams G. WIdespread increases in regional hypothalamic neuropeptide Y levels in acute cold-exposed rats Neuroscience. 54: 127-132. PMID 8515838 DOI: 10.1016/0306-4522(93)90388-V  0.427
1993 Trayhurn P, Thomas ME, Duncan JS, Nicol F, Arthur JR. Presence of the brown fat-specific mitochondrial uncoupling protein and iodothyronine 5'-deiodinase activity in subcutaneous adipose tissue of neonatal lambs. Febs Letters. 322: 76-8. PMID 8482372 DOI: 10.1016/0014-5793(93)81115-G  0.524
1993 Brander F, Keith JS, Trayhurn P. A 27-mer oligonucleotide probe for the detection and measurement of the mRNA for uncoupling protein in brown adipose tissue of different species Comparative Biochemistry and Physiology B. 104: 125-131. PMID 8448986 DOI: 10.1016/0305-0491(93)90348-9  0.406
1993 Dutta-Roy AK, Huang Y, Dunbar B, Trayhurn P. Purification and characterization of fatty acid-binding proteins from brown adipose tissue of the rat. Biochimica Et Biophysica Acta. 1169: 73-9. PMID 8334153 DOI: 10.1016/0005-2760(93)90084-M  0.463
1993 Trayhurn P, Thomas MEA, Keith JS. Postnatal development of uncoupling protein, uncoupling protein mRNA, and GLUT4 in adipose tissues of goats American Journal of Physiology-Regulatory Integrative and Comparative Physiology. 265. PMID 8214163 DOI: 10.1152/Ajpregu.1993.265.3.R676  0.519
1993 Trayhurn P. Brown adipose tissue: from thermal physiology to bioenergetics Journal of Biosciences. 18: 161-173. DOI: 10.1007/Bf02703113  0.503
1992 Knott RM, Trayhurn P, Hesketh JE. Changes in insulin-receptor mRNA levels in skeletal muscle and brown adipose tissue of weanling rats during fasting and refeeding. British Journal of Nutrition. 68: 583-592. PMID 1493128 DOI: 10.1079/Bjn19920117  0.407
1992 Nicol F, Lefranc H, Arthur JR, Trayhurn P. Types I and II iodothyronine 5'-deiodinase activities in perirenal brown adipose tissue of neonatal goats. Biochemical Society Transactions. 20: 336S. PMID 1487001 DOI: 10.1042/Bst020336S  0.456
1992 Trayhurn P, Thomas ME, Keith JS. Early postnatal changes in the brown fat-specific mitochondrial uncoupling protein in goat adipose tissues. Biochemical Society Transactions. 20. PMID 1487000 DOI: 10.1042/Bst020335S  0.483
1991 Soppela P, Nieminen M, Saarela S, Keith JS, Morrison JN, Macfarlane F, Trayhurn P. Brown fat-specific mitochondrial uncoupling protein in adipose tissues of newborn reindeer. American Journal of Physiology-Regulatory Integrative and Comparative Physiology. 260. PMID 2058749 DOI: 10.1152/Ajpregu.1991.260.6.R1229  0.433
1991 Arthur JR, Nicol F, Beckett GJ, Trayhurn P. Impairment of iodothyronine 5'-deiodinase activity in brown adipose tissue and its acute stimulation by cold in selenium deficiency. Canadian Journal of Physiology and Pharmacology. 69: 782-5. PMID 1913324 DOI: 10.1139/Y91-117  0.437
1991 Trayhurn P, Keith JS, Racey PA, Burnett AM. Immunological identification of uncoupling protein in interscapular "brown" adipose tissue of suckling and adult pipistrelle bats (Pipistrellus pipistrellus) Comparative Biochemistry and Physiology -- Part B: Biochemistry And. 99: 317-320. PMID 1764910 DOI: 10.1016/0305-0491(91)90048-I  0.474
1991 Saarela S, Keith JS, Hohtola E, Trayhurn P. Is the mammalian brown fat-specific mitochondrial uncoupling protein present in adipose tissues of birds ? Comparative Biochemistry and Physiology B. 100: 45-49. PMID 1756620 DOI: 10.1016/0305-0491(91)90082-O  0.517
1991 Bartness TJ, Milner R, Geloen A, Trayhurn P. Effects of high fat diets on hibernation and adipose tissue in Turkish hamsters. Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology. 161: 451-9. PMID 1744246 DOI: 10.1007/Bf00257899  0.386
1991 Pertwee RG, Nash K, Trayhurn P. Evidence that the hypothermic response of mice to delta-9-tetrahydrocannabinol is not mediated by changes in thermogenesis in brown adipose tissue. Canadian Journal of Physiology and Pharmacology. 69: 767-770. PMID 1655180 DOI: 10.1139/Y91-114  0.42
1990 Milner RE, Trayhurn P. Rapid quantitation of uncoupling protein in brown adipose tissue mitochondria by a dot immunobinding ("dot blot") procedure: application to the measurement of uncoupling protein in Richardson's ground squirrel, rats, and mice. Biochemistry and Cell Biology. 68: 973-979. PMID 2397100 DOI: 10.1139/O90-143  0.409
1990 Milner RE, Géloën A, Trayhurn P. A dot immunobinding assay for the rapid quantification of uncoupling protein in brown adipose tissue mitochondria. Biochemical Society Transactions. 18: 547-547. PMID 2276430 DOI: 10.1042/Bst0180547  0.473
1990 Trayhurn P, Wusteman MC. Lipogenesis in genetically diabetic (db/db) mice: developmental changes in brown adipose tissue, white adipose tissue and the liver. Biochimica Et Biophysica Acta. 1047: 168-174. PMID 2248973 DOI: 10.1016/0005-2760(90)90043-W  0.414
1990 Géloën A, Trayhurn P. Regulation of the level of uncoupling protein in brown adipose tissue by insulin requires the mediation of the sympathetic nervous system. Febs Letters. 267: 265-267. PMID 2199218 DOI: 10.1016/0014-5793(90)80941-B  0.382
1990 Geloen A, Trayhurn P. Regulation of the level of uncoupling protein in brown adipose tissue by insulin. American Journal of Physiology-Regulatory Integrative and Comparative Physiology. 258. PMID 2137990 DOI: 10.1152/Ajpregu.1990.258.2.R418  0.427
1990 Soppela P, Nieminen M, Saarela S, Keith JS, Morrison JN, Trayhurn P. Development of uncoupling protein in adipose tissues of reindeer. Biochemical Society Transactions. 18: 1270-1271. PMID 2088912 DOI: 10.1042/Bst0181270  0.478
1990 Géloën A, Arthur JR, Beckett GJ, Trayhurn P. Effect of selenium and iodine deficiency on the level of uncoupling protein in brown adipose tissue of rats. Biochemical Society Transactions. 18: 1269-1270. PMID 2088911 DOI: 10.1042/Bst0181269  0.464
1990 Knott RM, Hesketh JE, Trayhurn P. Insulin receptor gene expression in skeletal muscle and brown adipose tissue. Biochemical Society Transactions. 18: 1263-1263. PMID 2088906 DOI: 10.1042/Bst0181263  0.359
1990 Macfarlane F, Trayhurn P. Oligonucleotide probe for the cross-species measurement of the mRNA for uncoupling protein in brown adipose tissue. Biochemical Society Transactions. 18: 1261-1261. PMID 2088904 DOI: 10.1042/Bst0181261  0.411
1990 Nieminen M, Saarela S, Keith JS, Morrison JN, Trayhurn P. The presence of uncoupling protein in «brown» adipose tissue of reindeer Rangifer. 10: 29-30. DOI: 10.7557/2.10.5.953  0.484
1989 Milner RE, Wang LCH, Trayhurn P. Brown fat thermogenesis during hibernation and arousal in Richardson's ground squirrel. American Journal of Physiology-Regulatory Integrative and Comparative Physiology. 256. PMID 2912224 DOI: 10.1152/Ajpregu.1989.256.1.R42  0.458
1989 Trayhurn P, Howe A. Noradrenaline turnover in brown adipose tissue and the heart of fed and fasted golden hamsters. Canadian Journal of Physiology and Pharmacology. 67: 106-109. PMID 2713758 DOI: 10.1139/Y89-018  0.492
1989 Trayhurn P, Milner RE. A commentary on the interpretation of in vitro biochemical measures of brown adipose tissue thermogenesis Canadian Journal of Physiology and Pharmacology. 67: 811-819. PMID 2688850 DOI: 10.1139/Y89-128  0.448
1989 Trayhurn P. Thermogenesis and the energetics of pregnancy and lactation Canadian Journal of Physiology and Pharmacology. 67: 370-375. PMID 2667730 DOI: 10.1139/Y89-060  0.465
1989 Trayhurn P, Temple NJ, Aerde JV. Evidence from immunoblotting studies on uncoupling protein that brown adipose tissue is not present in the domestic pig. Canadian Journal of Physiology and Pharmacology. 67: 1480-1485. PMID 2627687 DOI: 10.1139/Y89-239  0.5
1989 Milner RE, Trayhurn P. Cold-induced changes in uncoupling protein and GDP binding sites in brown fat of ob/ob mice American Journal of Physiology-Regulatory Integrative and Comparative Physiology. 257. PMID 2548407 DOI: 10.1152/Ajpregu.1989.257.2.R292  0.433
1988 Milner RE, Trayhurn P. Evidence that the acute unmasking of GDP-binding sites in brown adipose tissue mitochondria is not dependent on mitochondrial swelling Biochemistry and Cell Biology. 66: 1226-1230. PMID 3242566 DOI: 10.1139/O88-140  0.425
1988 Milner RE, Wilson S, Arch JRS, Trayhurn P. Acute effects of a beta-adrenoceptor agonist (BRL 26830A) on rat brown-adipose-tissue mitochondria. Increased GDP binding and GDP-sensitive proton conductance without changes in the concentration of uncoupling protein. Biochemical Journal. 249: 759-763. PMID 2895635 DOI: 10.1042/Bj2490759  0.371
1988 Trayhurn P, Jennings G. Nonshivering thermogenesis and the thermogenic capacity of brown fat in fasted and/or refed mice American Journal of Physiology-Regulatory Integrative and Comparative Physiology. 254. PMID 2827526 DOI: 10.1152/Ajpregu.1988.254.1.R11  0.504
1988 Milner RE, Trayhurn P. Acute effects of cold on GDP binding and uncoupling protein concentration in brown adipose tissue mitochondria of genetically obese ( ob/ob ) mice Biochemical Society Transactions. 16: 1009-1010. DOI: 10.1042/Bst0161009  0.488
1987 Trayhurn P, Ashwell M, Jennings G, Richard D, Stirling DM. Effect of warm or cold exposure on GDP binding and uncoupling protein in rat brown fat. The American Journal of Physiology. 252: E237-43. PMID 3826341 DOI: 10.1152/Ajpendo.1987.252.2.E237  0.577
1987 Trayhurn P, Wusteman MC. Apparent dissociation between sympathetic activity and brown adipose tissue thermogenesis during pregnancy and lactation in golden hamsters. Canadian Journal of Physiology and Pharmacology. 65: 2396-2399. PMID 3449196 DOI: 10.1139/Y87-380  0.463
1987 Mercer SW, Trayhurn P. Effect of high fat diets on energy balance and thermogenesis in brown adipose tissue of lean and genetically obese ob/ob mice. Journal of Nutrition. 117: 2147-2153. PMID 3320290 DOI: 10.1093/Jn/117.12.2147  0.45
1987 Jennings G, Richard D, Trayhurn P. Effect of caging singly or in groups of different sizes on the thermogenic activity of interscapular brown adipose tissue in mice. Comparative Biochemistry and Physiology. a, Comparative Physiology. 85: 583-6. PMID 2878790 DOI: 10.1016/0300-9629(86)90451-2  0.577
1987 Trayhurn P, Jennings G. Functional atrophy of brown adipose tissue during lactation in mice. Effects of lactation and weaning on mitochondrial GDP binding and uncoupling protein. Biochemical Journal. 248: 273-276. PMID 2829824 DOI: 10.1042/Bj2480273  0.469
1986 Trayhurn P, Richard D. Brown adipose tissue thermogenesis and the energetics of pregnancy and lactation in rodents. Biochemical Society Transactions. 13: 826-8. PMID 4065414 DOI: 10.1042/Bst0130826  0.585
1986 Andrews JF, Richard D, Jennings G, Trayhurn P. Brown adipose tissue thermogenesis during pregnancy in mice. Annals of Nutrition & Metabolism. 30: 87-93. PMID 3963751 DOI: 10.1159/000177180  0.599
1986 Lean MEJ, James WPT, Jennings G, Trayhurn P. Brown adipose tissue uncoupling protein content in human infants, children and adults. Clinical Science. 71: 291-297. PMID 3757433 DOI: 10.1042/Cs0710291  0.456
1986 Trayhurn P, Mercer SW. Brown adipose tissue thermogenesis in obese animals Biochemical Society Transactions. 14: 236-239. PMID 3519314 DOI: 10.1042/Bst0140236  0.468
1986 Mercer SW, Trayhurn P. Effects of ciglitazone on insulin resistance and thermogenic responsiveness to acute cold in brown adipose tissue of genetically obese (ob/ob) mice Febs Letters. 195: 12-16. PMID 3510900 DOI: 10.1016/0014-5793(86)80120-X  0.478
1986 Trayhurn P, Jennings G. Evidence that fasting can induce a selective loss of uncoupling protein from brown adipose tissue mitochondria of mice. Bioscience Reports. 6: 805-810. PMID 3028525 DOI: 10.1007/Bf01117103  0.491
1986 Milner RE, Wilson S, Arch JRS, Trayhurn P. Are there one or two high-affinity binding sites for GDP in brown adipose tissue mitochondria? Biochemical Society Transactions. 14: 1201-1202. DOI: 10.1042/Bst0141201  0.402
1986 Wusteman M, Trayhurn P. Developmental changes in lipogenesis in interscapular brown adipose tissue of diabetic (db/db) mice Biochemical Society Transactions. 14: 1185-1185. DOI: 10.1042/Bst0141185  0.395
1986 Trayhurn P, Jennings G. Uncoupling protein content of brown adipose tissue mitochondria in fasted and refed mice Biochemical Society Transactions. 14: 1184-1185. DOI: 10.1042/Bst0141184  0.507
1986 Lean MEJ, James WPT, Jennings G, Trayhurn P. Brown adipose tissue uncoupling protein in adult humans Biochemical Society Transactions. 14: 289-290. DOI: 10.1042/Bst0140289  0.423
1986 Lean MEJ, James WPT, Jennings G, Trayhurn P. Brown adipose tissue uncoupling protein in infants and children Biochemical Society Transactions. 14: 288-289. DOI: 10.1042/Bst0140288  0.365
1986 Ashwell M, Jennings G, Stirling DM, Trayhurn P. Decrease in mitochondrial GDP binding without parallel changes in uncoupling protein in brown adipose tissue of the guinea pig Biochemical Society Transactions. 14: 283-284. DOI: 10.1042/Bst0140283  0.451
1985 Richard D, Trayhurn P. Energetic efficiency during pregnancy in mice fed ad libitum or pair-fed to the normal energy intake of unmated animals. The Journal of Nutrition. 115: 593-600. PMID 3998861 DOI: 10.1093/Jn/115.5.593  0.527
1984 Richard D, Trayhurn P. Effect of exercise training on the rates of fatty acid synthesis in mice. Canadian Journal of Physiology and Pharmacology. 62: 695-9. PMID 6744113 DOI: 10.1139/Y84-114  0.559
1984 Mercer SW, Trayhurn P. Effect of High Fat Diets on the Thermogenic Activity of Brown Adipose Tissue in Cold-Acclimated Mice Journal of Nutrition. 114: 1151-1158. PMID 6726479 DOI: 10.1093/Jn/114.6.1151  0.479
1984 Mercer SW, Trayhurn P. The development of insulin resistance in brown adipose tissue may impair the acute cold-induced activation of thermogenesis in genetically obese (ob/ob) mice Bioscience Reports. 4: 933-940. PMID 6395917 DOI: 10.1007/Bf01116891  0.47
1984 Trayhurn P, Douglas JB. Fatty acid synthesis in brown adipose tissue of the Mongolian gerbil (Meriones unguiculatus): influence of acclimation temperature on synthesis in brown adipose tissue and the liver in relation to whole-body synthesis. Comparative Biochemistry and Physiology B. 78: 601-607. PMID 6383702 DOI: 10.1016/0305-0491(84)90105-6  0.415
1984 Trayhurn P, Richard D, Jennings G, Ashwell M. Adaptive changes in the concentration of the mitochondrial 'uncoupling' protein in brown adipose tissue of hamsters acclimated at different temperatures. Bioscience Reports. 3: 1077-84. PMID 6320922 DOI: 10.1007/Bf01120199  0.612
1984 Trayhurn P, Mercer S. Thermogenesis and lipogenesis (in brown adipose tissue) Trends in Biochemical Sciences. 9: 434. DOI: 10.1016/0968-0004(84)90149-X  0.486
1983 Rothwell NJ, Stock MJ, Trayhurn P. Reduced lipogenesis in cafeteria-fed rats exhibiting diet-induced thermogenesis Bioscience Reports. 3: 217-224. PMID 6860780 DOI: 10.1007/Bf01122453  0.395
1983 Trayhurn P. Decreased capacity for non-shivering thermogenesis during lactation in mice. PflüGers Archiv: European Journal of Physiology. 398: 264-265. PMID 6634385 DOI: 10.1007/Bf00657164  0.328
1983 Sahakian BJ, Trayhurn P, Wallace M, Deeley R, Winn P, Robbins TW, Everitt BJ. Increased weight gain and reduced activity in brown adipose tissue produced by depletion of hypothalamic noradrenaline. Neuroscience Letters. 39: 321-6. PMID 6633961 DOI: 10.1016/0304-3940(83)90320-8  0.415
1983 Ashwell M, Jennings G, Richard D, Stirling DM, Trayhurn P. Effect of acclimation temperature on the concentration of the mitochondrial 'uncoupling' protein measured by radioimmunoassay in mouse brown adipose tissue. Febs Letters. 161: 108-12. PMID 6309573 DOI: 10.1016/0014-5793(83)80740-6  0.591
1983 Ashwell M, Jennings G, Trayhurn P. Evidence from radioimmunoassay for a decreased concentration of mitochondrial ‘uncoupling’ protein from brown adipose tissue of genetically obese (ob/ob) mice Biochemical Society Transactions. 11: 727-728. DOI: 10.1042/Bst0110727  0.492
1982 Goodbody AE, Trayhurn P. Studies on the activity of brown adipose tissue in suckling, pre-obese, obob mice Biochimica Et Biophysica Acta. 680: 119-126. PMID 7093244 DOI: 10.1016/0005-2728(82)90002-0  0.528
1982 Sahakian BJ, Burdess C, Luckhurst H, Trayhurn P. Hyperactivity and obesity: the interaction of social isolation and cafeteria feeding. Physiology & Behavior. 28: 117-24. PMID 7079310 DOI: 10.1016/0031-9384(82)90112-3  0.342
1982 Trayhurn P, Jones PM, McGuckin MM, Goodbody AE. Effects of overfeeding on energy balance and brown fat thermogenesis in obese ( ob / ob ) mice Nature. 295: 323-325. PMID 7057896 DOI: 10.1038/295323A0  0.453
1982 Trayhurn P, Douglas JB, McGuckin MM. Brown adipose tissue thermogenesis is ‘suppressed’ during lactation in mice Nature. 298: 59-60. PMID 6283369 DOI: 10.1038/298059A0  0.542
1981 Brandt PAvd, Trayhurn P. Suppression of fatty acids synthesis in brown adipose tissue of mice fed diets rich in long chain fatty acids. Biochimica Et Biophysica Acta. 665: 602-607. PMID 7295753 DOI: 10.1016/0005-2760(81)90276-9  0.422
1981 Trayhurn P. Fatty acid synthesis in mouse brown adipose tissue the influence of environmental temperature on the proportion of whole-body fatty acid synthesis in brown adipose tissue and the liver Biochimica Et Biophysica Acta. 664: 549-560. PMID 7272321 DOI: 10.1016/0005-2760(81)90132-6  0.435
1981 Fraser DR, Trayhurn P. Calcium transport by brown-adipose-tissue mitochondria from lean and genetically obese ( ob/ob ) mice Biochemical Society Transactions. 9: 470-471. DOI: 10.1042/Bst0090470  0.439
1980 Trayhurn P. Fatty acid synthesis in brown adipose tissue in relation to whole body synthesis in the cold-acclimated golden hamster (Mesocricetus auratus). Biochimica Et Biophysica Acta. 620: 10-17. PMID 7417474 DOI: 10.1016/0005-2760(80)90179-4  0.478
1980 Trayhurn P. Fatty acid synthesis in brown adipose tissue of cold-acclimated mice and golden hamsters (Mesocricetus auratus) Biochemical Society Transactions. 8: 375-375. PMID 7399103 DOI: 10.1042/Bst0080375  0.45
1980 Thurlby PL, Trayhurn P. Regional blood flow in genetically obese (ob/ob) mice. The importance of brown adipose tissue to the reduced energy expenditure on non-shivering thermogenesis. PflüGers Archiv: European Journal of Physiology. 385: 193-201. PMID 7190682 DOI: 10.1007/Bf00647457  0.427
1980 Brooks SL, Rothwell NJ, Stock MJ, Goodbody AE, Trayhurn P. Increased proton conductance pathway in brown adipose tissue mitochondria of rats exhibiting diet-induced thermogenesis Nature. 286: 274-276. PMID 6250051 DOI: 10.1038/286274A0  0.485
1979 Thurlby PL, Trayhurn P. The role of thermoregulatory thermogenesis in the development of obesity in genetically-obese ( ob/ob ) mice pair-fed with lean siblings British Journal of Nutrition. 42: 377-385. PMID 508700 DOI: 10.1079/Bjn19790127  0.369
1979 Trayhurn P. Fatty acid synthesis in vivo in brown adipose tissue, liver and white adipose tissue of the cold‐acclimated rat Febs Letters. 104: 13-16. PMID 477972 DOI: 10.1016/0014-5793(79)81075-3  0.415
1979 Trayhurn P, James WPT, Gurr MI. Studies on the body composition, fat distribution and fat cell size and number of 'Ad', a new obese mutant mouse. British Journal of Nutrition. 41: 211-221. PMID 420754 DOI: 10.1079/Bjn19790027  0.422
1978 Trayhurn P, James WPT. Thermoregulation and non-shivering thermogenesis in the genetically obese (ob/ob) mouse. PflüGers Archiv: European Journal of Physiology. 373: 189-193. PMID 565045 DOI: 10.1007/Bf00584859  0.385
1977 Trayhurn P, Thurlby PL, James WPT. Thermogenic defect in pre-obese ob/ob mice Nature. 266: 60-62. PMID 840297 DOI: 10.1038/266060A0  0.396
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