Year |
Citation |
Score |
2022 |
Chatzopoulou M, Conole D, Emer E, Rowley JA, Willis NJ, Squire SE, Gill B, Brough S, Wilson FX, Wynne GM, Davies SG, Davies KE, Russell AJ. Structure-activity relationships of 2-pyrimidinecarbohydrazides as utrophin modulators for the potential treatment of Duchenne muscular dystrophy. Bioorganic & Medicinal Chemistry. 69: 116812. PMID 35772287 DOI: 10.1016/j.bmc.2022.116812 |
0.573 |
|
2020 |
Chatzopoulou M, Emer E, Lecci C, Rowley JA, Casagrande AS, Moir L, Squire SE, Davies SG, Harriman S, Wynne GM, Wilson FX, Davies KE, Russell AJ. Decreasing HepG2 Cytotoxicity by Lowering the Lipophilicity of Benzo[d]oxazolephosphinate Ester Utrophin Modulators. Acs Medicinal Chemistry Letters. 11: 2421-2427. PMID 33335663 DOI: 10.1021/acsmedchemlett.0c00405 |
0.571 |
|
2020 |
Babbs A, Berg A, Chatzopoulou M, Davies KE, Davies SG, Edwards B, Elsey DJ, Emer E, Figuccia ALA, Fletcher AM, Guiraud S, Harriman S, Moir L, Robinson N, Rowley JA, et al. Synthesis of SMT022357 enantiomers and evaluation in a Duchenne muscular dystrophy mouse model. Tetrahedron. 76: 130819. PMID 32713969 DOI: 10.1016/J.Tet.2019.130819 |
0.639 |
|
2020 |
Babbs A, Berg A, Chatzopoulou M, Davies KE, Davies SG, Edwards B, Elsey D, Emer E, Guiraud S, Harriman S, Lecci C, Moir L, Peters D, Robinson N, Rowley J, et al. 2-Arylbenzo[d]oxazole phosphinate esters as second-generation modulators of utrophin for the treatment of Duchenne Muscular Dystrophy. Journal of Medicinal Chemistry. PMID 32551645 DOI: 10.1021/Acs.Jmedchem.0C00807 |
0.613 |
|
2020 |
Babbs A, Berg A, Chatzopoulou M, Davies KE, Davies SG, Edwards B, Elsey DJ, Emer E, Figuccia AL, Fletcher AM, Guiraud S, Harriman S, Moir L, Robinson N, Rowley JA, et al. Synthesis of SMT022357 enantiomers and in vivo evaluation in a Duchenne muscular dystrophy mouse model Tetrahedron. 76: 130819. DOI: 10.1016/j.tet.2019.130819 |
0.637 |
|
2019 |
Chatzopoulou M, Claridge TDW, Davies KE, Davies SG, Elsey D, Emer E, Fletcher AM, Harriman S, Robinson N, Rowley J, Russell AJ, Tinsley J, Weaver R, Wilkinson I, Willis N, et al. Isolation, structural identification, synthesis, and pharmacological profiling of 1,2-trans-dihydro-1,2-diol metabolites of the utrophin modulator ezutromid. Journal of Medicinal Chemistry. PMID 31599580 DOI: 10.1021/Acs.Jmedchem.9B01547 |
0.655 |
|
2017 |
Taylor N, Emer E, Preshlock S, Schedler M, Tredwell M, Verhoog S, Mercier J, Genicot C, Gouverneur VE. De-Risking the Cu-Mediated 18F-Fluorination of Heterocyclic PET Radioligands. Journal of the American Chemical Society. PMID 28548849 DOI: 10.1021/Jacs.7B03131 |
0.513 |
|
2017 |
Wynne G, Vuorinen A, Emer E, Conole D, Chatzopoulou M, Davies S, Russell A, Guiraud S, Squire S, Berg A, Edwards B, Hemming S, Kennedy T, Moir L, Davies K, et al. Discovery of small molecule utrophin modulators for the therapy of Duchenne muscular dystrophy Neuromuscular Disorders. 27. DOI: 10.1016/J.Nmd.2017.06.348 |
0.502 |
|
2014 |
Emer E, Twilton J, Tredwell M, Calderwood S, Collier TL, Liégault B, Taillefer M, Gouverneur V. Diversity-oriented approach to CF3CHF-, CF3CFBr-, CF3CF2-, (CF3)2CH-, and CF3(SCF3)CH-substituted arenes from 1-(diazo-2,2,2-trifluoroethyl)arenes. Organic Letters. 16: 6004-7. PMID 25379614 DOI: 10.1021/Ol5030184 |
0.527 |
|
2014 |
Emer E, Pfeifer L, Brown JM, Gouverneur V. cis-Specific hydrofluorination of alkenylarenes under palladium catalysis through an ionic pathway. Angewandte Chemie (International Ed. in English). 53: 4181-5. PMID 24644083 DOI: 10.1002/Anie.201310056 |
0.624 |
|
2014 |
Knochel P, Haas D, Emer E, Pfeifer L, Brown JM, Gouverneur V. Palladium-Catalyzed Hydrofluorination of Alkenylarenes Synfacts. 10: 746-746. DOI: 10.1055/S-0033-1339153 |
0.581 |
|
2014 |
Gualandi A, Canestrari P, Emer E, Cozzi PG. ChemInform Abstract: A Straightforward Organocatalytic Alkylation of 2-Arylacetaldehydes: An Approach Towards Bisabolanes. Cheminform. 45: no-no. DOI: 10.1002/CHIN.201434056 |
0.565 |
|
2014 |
Gualandi A, Canestrari P, Emer E, Cozzi PG. A straightforward organocatalytic alkylation of 2-arylacetaldehydes: An approach towards bisabolanes Advanced Synthesis and Catalysis. 356: 528-536. DOI: 10.1002/Adsc.201300250 |
0.665 |
|
2013 |
Quaglia D, Pori M, Galletti P, Emer E, Paradisi F, Giacomini D. His-tagged Horse Liver Alcohol Dehydrogenase: Immobilization and application in the bio-based enantioselective synthesis of (S)-arylpropanols Dedicated to Prof. Gianfranco Cainelli on the occasion of his 80th birthday Process Biochemistry. 48: 810-818. DOI: 10.1016/J.Procbio.2013.03.016 |
0.712 |
|
2012 |
Gualandi A, Petruzziello D, Emer E, Cozzi PG. A general stereoselective enamine mediated alkylation of α-substituted aldehydes. Chemical Communications (Cambridge, England). 48: 3614-6. PMID 22396955 DOI: 10.1039/C2Cc17482K |
0.721 |
|
2012 |
Capdevila MG, Emer E, Gualandi A, Petruzziello D, Grilli S, Cozzi PG. Organocatalytic Stereoselective α-Formylation of Ketones Chemcatchem. 4: 968-971. DOI: 10.1002/Cctc.201200122 |
0.71 |
|
2012 |
GuiterasCapdevila M, Emer E, Benfatti F, Gualandi A, Wilson CM, Cozzi PG. Indium(III)-Promoted Organocatalytic Enantioselective α-Alkylation of Aldehydes with Benzylic and Benzhydrylic Alcohols Asian Journal of Organic Chemistry. 1: 38-42. DOI: 10.1002/Ajoc.201200013 |
0.707 |
|
2011 |
Gualandi A, Emer E, Guiteras Capdevila M, Cozzi PG. Highly enantioselective α alkylation of aldehydes with 1,3-benzodithiolylium tetrafluoroborate: a formal organocatalytic α alkylation of aldehydes by the carbenium ion. Angewandte Chemie (International Ed. in English). 50: 7842-6. PMID 21714053 DOI: 10.1002/Anie.201102562 |
0.715 |
|
2011 |
Alesi S, Emer E, Capdevila MG, Petruzziello D, Gualandi A, Cozzi PG. Enantio and diastereoselective addition of phenylacetylene to racemic α-chloroketones. Molecules (Basel, Switzerland). 16: 5298-314. PMID 21701439 DOI: 10.3390/Molecules16065298 |
0.722 |
|
2011 |
Sinisi R, Vita MV, Gualandi A, Emer E, Cozzi PG. S(N)1-type reactions in the presence of water: indium(III)-promoted highly enantioselective organocatalytic propargylation of aldehydes. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 7404-8. PMID 21618635 DOI: 10.1002/Chem.201100729 |
0.682 |
|
2011 |
Cozzi PG, Emer E, Gualandi A. Atroposelective organocatalysis. Angewandte Chemie (International Ed. in English). 50: 3847-9. PMID 21448867 DOI: 10.1002/anie.201008031 |
0.643 |
|
2011 |
Gualandi A, Emer E, Capdevila MG, Cozzi PG. Enantioselective α-Alkylation of Aldehydes Using1,3-Benzodithiolylium Tetrafluoroborate Synfacts. 2011: 1018-1018. DOI: 10.1055/S-0030-1260918 |
0.589 |
|
2011 |
Emer E, Sinisi R, Capdevila MG, Petruzziello D, De Vincentiis F, Cozzi PG. Direct nucleophilic SN1-type reactions of alcohols European Journal of Organic Chemistry. 647-666. DOI: 10.1002/Ejoc.201001474 |
0.595 |
|
2011 |
Gualandi A, Emer E, Capdevila MG, Cozzi PG. Inside Cover: Highly Enantioselective α Alkylation of Aldehydes with 1,3-Benzodithiolylium Tetrafluoroborate: A Formal Organocatalytic α Alkylation of Aldehydes by the Carbenium Ion (Angew. Chem. Int. Ed. 34/2011) Angewandte Chemie International Edition. 50: 7706-7706. DOI: 10.1002/Anie.201104187 |
0.715 |
|
2010 |
Galletti P, Emer E, Gucciardo G, Quintavalla A, Pori M, Giacomini D. Chemoenzymatic synthesis of (2S)-2-arylpropanols through a dynamic kinetic resolution of 2-arylpropanals with alcohol dehydrogenases. Organic & Biomolecular Chemistry. 8: 4117-23. PMID 20625608 DOI: 10.1039/C005098A |
0.638 |
|
2009 |
Emer E, Galletti P, Giacomini D. Evaluation of 6-APA as a New Organocatalyst for a Direct Cross-Aldol Reaction European Journal of Organic Chemistry. 2009: 3155-3160. DOI: 10.1002/Ejoc.200900181 |
0.612 |
|
2008 |
Emer E, Galletti P, Giacomini D. A temperature study on a stereoselective organocatalyzed aldol reaction in water Tetrahedron. 64: 11205-11208. DOI: 10.1016/J.Tet.2008.09.059 |
0.591 |
|
2006 |
Bandini M, Emer E, Tommasi S, Umani-Ronchi A. Innovative catalytic protocols for the ring-closing Friedel-crafts-type alkylation and alkenylation of arenes European Journal of Organic Chemistry. 3527-3544. DOI: 10.1002/Ejoc.200500995 |
0.752 |
|
2005 |
Balducci D, Emer E, Piccinelli F, Porzi G, Recanatini M, Sandri S. Synthesis and conformational preferences of cyclic unnatural di- and tripeptides containing an l-valine unit: Part 2 ☆ Tetrahedron-Asymmetry. 16: 3785-3794. DOI: 10.1016/J.Tetasy.2005.10.030 |
0.715 |
|
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