Julio Scharfstein - Publications

Affiliations: 
Instituto de Biofisica Carlos Chagas Filho Universidade Federal do Rio De Janeiro (UFRJ) 

69 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 da Mota JB, Echevarria-Lima J, Kyle-Cezar F, Melo M, Bellio M, Scharfstein J, Oliveira AC. IL-18R signaling is required for γδ T cell response and confers resistance to Trypanosoma cruzi infection. Journal of Leukocyte Biology. PMID 32450614 DOI: 10.1002/Jlb.4Ma0420-568R  0.357
2019 Silva LS, Pinheiro AS, Teixeira DE, Silva-Aguiar RP, Peruchetti DB, Scharfstein J, Caruso-Neves C, Pinheiro AAS. Kinins Released by Erythrocytic Stages of Enhance Adhesion of Infected Erythrocytes to Endothelial Cells and Increase Blood Brain Barrier Permeability via Activation of Bradykinin Receptors. Frontiers in Medicine. 6: 75. PMID 31058153 DOI: 10.3389/Fmed.2019.00075  0.36
2018 Almeida-da-Silva CLC, Ramos-Junior ES, Morandini AC, Rocha GDC, Marinho Y, Tamura AS, de Andrade KQ, Bellio M, Savio LEB, Scharfstein J, Ojcius DM, Coutinho-Silva R. P2X7 receptor-mediated leukocyte recruitment and Porphyromonas gingivalis clearance requires IL-1β production and autocrine IL-1 receptor activation. Immunobiology. PMID 30429052 DOI: 10.1016/J.Imbio.2018.10.008  0.312
2018 Johnson L, Almeida-da-Silva CLC, Takiya CM, Figliuolo V, Rocha GM, Weissmüller G, Scharfstein J, Coutinho-Silva R, Ojcius DM. Oral infection of mice with Fusobacterium nucleatum results in macrophage recruitment to the dental pulp and bone resorption. Biomedical Journal. 41: 184-193. PMID 30080658 DOI: 10.1016/J.Bj.2018.05.001  0.335
2018 Scharfstein J. Subverting bradykinin-evoked inflammation by co-opting the contact system: lessons from survival strategies of Trypanosoma cruzi. Current Opinion in Hematology. 25: 347-357. PMID 30028741 DOI: 10.1097/Moh.0000000000000444  0.35
2017 Scharfstein J, Ramos PIP, Barral-Netto M. G Protein-Coupled Kinin Receptors and Immunity Against Pathogens. Advances in Immunology. 136: 29-84. PMID 28950949 DOI: 10.1016/Bs.Ai.2017.05.007  0.394
2017 Nascimento CR, Andrade D, Carvalho-Pinto CE, Serra RR, Vellasco L, Brasil G, Ramos-Junior ES, da Mota JB, Almeida LN, Andrade MV, Correia Soeiro MN, Juliano L, Alvarenga PH, Oliveira AC, Sicuro FL, ... ... Scharfstein J, et al. Mast Cell Coupling to the Kallikrein-Kinin System Fuels Intracardiac Parasitism and Worsens Heart Pathology in Experimental Chagas Disease. Frontiers in Immunology. 8: 840. PMID 28824610 DOI: 10.3389/Fimmu.2017.00840  0.394
2015 Ramos-Junior ES, Morandini AC, Almeida-da-Silva CL, Franco EJ, Potempa J, Nguyen KA, Oliveira AC, Zamboni DS, Ojcius DM, Scharfstein J, Coutinho-Silva R. A Dual Role for P2X7 Receptor during Porphyromonas gingivalis Infection. Journal of Dental Research. 94: 1233-42. PMID 26152185 DOI: 10.1177/0022034515593465  0.317
2014 Svensjö E, Nogueira De Almeida L, Vellasco L, Juliano L, Scharfstein J. Ecotin-Like ISP of L. major Promastigotes Fine-Tunes Macrophage Phagocytosis by Limiting the Pericellular Release of Bradykinin from Surface-Bound Kininogens: A Survival Strategy Based on the Silencing of Proinflammatory G-Protein Coupled Kinin B2 and B1 Receptors Mediators of Inflammation. 2014. PMID 25294952 DOI: 10.1155/2014/143450  0.362
2014 Schmitz V, Almeida LN, Svensjö E, Monteiro AC, Köhl J, Scharfstein J. C5a and bradykinin receptor cross-talk regulates innate and adaptive immunity in Trypanosoma cruzi infection. Journal of Immunology (Baltimore, Md. : 1950). 193: 3613-23. PMID 25187655 DOI: 10.4049/Jimmunol.1302417  0.406
2014 Morandini AC, Ramos-Junior ES, Potempa J, Nguyen KA, Oliveira AC, Bellio M, Ojcius DM, Scharfstein J, Coutinho-Silva R. Porphyromonas gingivalis fimbriae dampen P2X7-dependent interleukin-1β secretion. Journal of Innate Immunity. 6: 831-45. PMID 24925032 DOI: 10.1159/000363338  0.308
2012 Nico D, Feijó DF, Maran N, Morrot A, Scharfstein J, Palatnik M, Palatnik-de-Sousa CB. Resistance to visceral leishmaniasis is severely compromised in mice deficient of bradykinin B2-receptors. Parasites & Vectors. 5: 261. PMID 23151408 DOI: 10.1186/1756-3305-5-261  0.329
2012 Rust NM, Papa MP, Scovino AM, da Silva MM, Calzavara-Silva CE, Marques ET, Peçanha LM, Scharfstein J, Arruda LB. Bradykinin enhances Sindbis virus infection in human brain microvascular endothelial cells. Virology. 422: 81-91. PMID 22047990 DOI: 10.1016/J.Virol.2011.10.003  0.334
2012 Svensjö E, Saraiva EM, Amendola RS, Barja-Fidalgo C, Bozza MT, Lerner EA, Teixeira MM, Scharfstein J. Maxadilan, the Lutzomyia longipalpis vasodilator, drives plasma leakage via PAC1-CXCR1/2-pathway. Microvascular Research. 83: 185-93. PMID 22036674 DOI: 10.1016/J.Mvr.2011.10.003  0.335
2012 Andrade D, Serra R, Svensjö E, Lima AP, Ramos ES, Fortes FS, Morandini AC, Morandi V, Soeiro Mde N, Tanowitz HB, Scharfstein J. Trypanosoma cruzi invades host cells through the activation of endothelin and bradykinin receptors: a converging pathway leading to chagasic vasculopathy. British Journal of Pharmacology. 165: 1333-47. PMID 21797847 DOI: 10.1111/J.1476-5381.2011.01609.X  0.307
2011 Scharfstein J, Andrade D. Infection-associated vasculopathy in experimental chagas disease pathogenic roles of endothelin and kinin pathways. Advances in Parasitology. 76: 101-27. PMID 21884889 DOI: 10.1016/B978-0-12-385895-5.00005-0  0.432
2010 Coelho dos Santos JS, Menezes CA, Villani FN, Magalhães LM, Scharfstein J, Gollob KJ, Dutra WO. Captopril increases the intensity of monocyte infection by Trypanosoma cruzi and induces human T helper type 17 cells. Clinical and Experimental Immunology. 162: 528-36. PMID 20964644 DOI: 10.1111/j.1365-2249.2010.04270.x  0.315
2010 Scharfstein J, Gomes Jde A, Correa-Oliveira R. Back to the future in Chagas disease: from animal models to patient cohort studies, progress in immunopathogenesis research. Memorias Do Instituto Oswaldo Cruz. 187-98. PMID 19753474 DOI: 10.1590/S0074-02762009000900025  0.302
2009 Monteiro AC, Scovino A, Raposo S, Gaze VM, Cruz C, Svensjö E, Narciso MS, Colombo AP, Pesquero JB, Feres-Filho E, Nguyen KA, Sroka A, Potempa J, Scharfstein J. Kinin danger signals proteolytically released by gingipain induce Fimbriae-specific IFN-gamma- and IL-17-producing T cells in mice infected intramucosally with Porphyromonas gingivalis. Journal of Immunology (Baltimore, Md. : 1950). 183: 3700-11. PMID 19687097 DOI: 10.4049/Jimmunol.0900895  0.388
2009 Grab DJ, Garcia-Garcia JC, Nikolskaia OV, Kim YV, Brown A, Pardo CA, Zhang Y, Becker KG, Wilson BA, de A Lima AP, Scharfstein J, Dumler JS. Protease activated receptor signaling is required for African trypanosome traversal of human brain microvascular endothelial cells. Plos Neglected Tropical Diseases. 3: e479. PMID 19621073 DOI: 10.1371/Journal.Pntd.0000479  0.336
2009 Schmitz V, Svensjö E, Serra RR, Teixeira MM, Scharfstein J. Proteolytic generation of kinins in tissues infected by Trypanosoma cruzi depends on CXC chemokine secretion by macrophages activated via Toll-like 2 receptors. Journal of Leukocyte Biology. 85: 1005-14. PMID 19293401 DOI: 10.1189/Jlb.1108693  0.395
2009 Villalta F, Scharfstein J, Ashton AW, Tyler KM, Guan F, Mukherjee S, Lima MF, Alvarez S, Weiss LM, Huang H, Machado FS, Tanowitz HB. Perspectives on the Trypanosoma cruzi-host cell receptor interactions. Parasitology Research. 104: 1251-60. PMID 19283409 DOI: 10.1007/S00436-009-1383-3  0.335
2008 Scharfstein J, Monteiro AC, Schmitz V, Svensjö E. Angiotensin-converting enzyme limits inflammation elicited by Trypanosoma cruzi cysteine proteases: a peripheral mechanism regulating adaptive immunity via the innate kinin pathway. Biological Chemistry. 389: 1015-24. PMID 18979626 DOI: 10.1515/Bc.2008.126  0.416
2008 Scharfstein J, Lima AP. Roles of naturally occurring protease inhibitors in the modulation of host cell signaling and cellular invasion by Trypanosoma cruzi. Sub-Cellular Biochemistry. 47: 140-54. PMID 18512348 DOI: 10.1007/978-0-387-78267-6_11  0.447
2008 Dos Santos Monteiro AC, de Oliveira Neto OB, Del Sarto RP, de Magalhães MT, Lima JN, Lacerda AF, Oliveira RS, Scharfstein J, da Silva MC, Valencia JW, Jiménez AV, Grossi-de-Sa MF. A recombinant form of chagasin from Trypanosoma cruzi: inhibitory activity on insect cysteine proteinases. Pest Management Science. 64: 755-60. PMID 18318460 DOI: 10.1002/Ps.1553  0.354
2008 dos Reis FC, Smith BO, Santos CC, Costa TF, Scharfstein J, Coombs GH, Mottram JC, Lima AP. The role of conserved residues of chagasin in the inhibition of cysteine peptidases. Febs Letters. 582: 485-90. PMID 18201565 DOI: 10.1016/J.Febslet.2008.01.008  0.349
2007 Monteiro AC, Schmitz V, Morrot A, de Arruda LB, Nagajyothi F, Granato A, Pesquero JB, Müller-Esterl W, Tanowitz HB, Scharfstein J. Bradykinin B2 Receptors of dendritic cells, acting as sensors of kinins proteolytically released by Trypanosoma cruzi, are critical for the development of protective type-1 responses. Plos Pathogens. 3: e185. PMID 18052532 DOI: 10.1371/Journal.Ppat.0030185  0.344
2007 Scharfstein J, Schmitz V, Svensjö E, Granato A, Monteiro AC. Kininogens coordinate adaptive immunity through the proteolytic release of bradykinin, an endogenous danger signal driving dendritic cell maturation. Scandinavian Journal of Immunology. 66: 128-136. PMID 17635790 DOI: 10.1111/J.1365-3083.2007.01983.X  0.419
2007 Wang SX, Pandey KC, Scharfstein J, Whisstock J, Huang RK, Jacobelli J, Fletterick RJ, Rosenthal PJ, Abrahamson M, Brinen LS, Rossi A, Sali A, McKerrow JH. The structure of chagasin in complex with a cysteine protease clarifies the binding mode and evolution of an inhibitor family. Structure (London, England : 1993). 15: 535-43. PMID 17502099 DOI: 10.1016/J.Str.2007.03.012  0.324
2007 Reis FC, Costa TF, Sulea T, Mezzetti A, Scharfstein J, Brömme D, Ménard R, Lima AP. The propeptide of cruzipain--a potent selective inhibitor of the trypanosomal enzymes cruzipain and brucipain, and of the human enzyme cathepsin F. The Febs Journal. 274: 1224-34. PMID 17298440 DOI: 10.1111/J.1742-4658.2007.05666.X  0.36
2006 Monteiro AC, Schmitz V, Svensjo E, Gazzinelli RT, Almeida IC, Todorov A, de Arruda LB, Torrecilhas AC, Pesquero JB, Morrot A, Bouskela E, Bonomo A, Lima AP, Müller-Esterl W, Scharfstein J. Cooperative activation of TLR2 and bradykinin B2 receptor is required for induction of type 1 immunity in a mouse model of subcutaneous infection by Trypanosoma cruzi. Journal of Immunology (Baltimore, Md. : 1950). 177: 6325-35. PMID 17056563 DOI: 10.4049/Jimmunol.177.9.6325  0.407
2006 Nikolskaia OV, de A Lima AP, Kim YV, Lonsdale-Eccles JD, Fukuma T, Scharfstein J, Grab DJ. Blood-brain barrier traversal by African trypanosomes requires calcium signaling induced by parasite cysteine protease. The Journal of Clinical Investigation. 116: 2739-47. PMID 16998589 DOI: 10.1172/Jci27798  0.35
2006 dos Reis FC, Júdice WA, Juliano MA, Juliano L, Scharfstein J, Lima AP. The substrate specificity of cruzipain 2, a cysteine protease isoform from Trypanosoma cruzi. Fems Microbiology Letters. 259: 215-20. PMID 16734782 DOI: 10.1111/J.1574-6968.2006.00267.X  0.32
2006 Santos CC, Scharfstein J, Lima AP. Role of chagasin-like inhibitors as endogenous regulators of cysteine proteases in parasitic protozoa. Parasitology Research. 99: 323-4. PMID 16636845 DOI: 10.1007/S00436-006-0195-Y  0.353
2006 Salmon D, do Aido-Machado R, Diehl A, Leidert M, Schmetzer O, de A Lima AP, Scharfstein J, Oschkinat H, Pires JR. Solution structure and backbone dynamics of the Trypanosoma cruzi cysteine protease inhibitor chagasin. Journal of Molecular Biology. 357: 1511-21. PMID 16490204 DOI: 10.1016/J.Jmb.2006.01.064  0.346
2006 Scharfstein J. Parasite cysteine proteinase interactions with alpha 2-macroglobulin or kininogens: differential pathways modulating inflammation and innate immunity in infection by pathogenic trypanosomatids. Immunobiology. 211: 117-25. PMID 16446176 DOI: 10.1016/J.Imbio.2005.10.014  0.439
2006 Svensjö E, Batista PR, Brodskyn CI, Silva R, Lima AP, Schmitz V, Saraiva E, Pesquero JB, Mori MA, Müller-Esterl W, Scharfstein J. Interplay between parasite cysteine proteases and the host kinin system modulates microvascular leakage and macrophage infection by promastigotes of the Leishmania donovani complex. Microbes and Infection. 8: 206-20. PMID 16203170 DOI: 10.1016/J.Micinf.2005.06.016  0.424
2005 Penha LL, Mendonça-Previato L, Previato JO, Scharfstein J, Heise N, Lima AP. Cloning and characterization of the phosphoglucomutase of Trypanosoma cruzi and functional complementation of a Saccharomyces cerevisiae PGM null mutant. Glycobiology. 15: 1359-67. PMID 16037487 DOI: 10.1093/Glycob/Cwj023  0.379
2005 Santos CC, Sant'anna C, Terres A, Cunha-e-Silva NL, Scharfstein J, de A Lima AP. Chagasin, the endogenous cysteine-protease inhibitor of Trypanosoma cruzi, modulates parasite differentiation and invasion of mammalian cells. Journal of Cell Science. 118: 901-15. PMID 15713748 DOI: 10.1242/Jcs.01677  0.399
2004 Aparicio IM, Scharfstein J, Lima AP. A new cruzipain-mediated pathway of human cell invasion by Trypanosoma cruzi requires trypomastigote membranes. Infection and Immunity. 72: 5892-902. PMID 15385491 DOI: 10.1128/Iai.72.10.5892-5902.2004  0.409
2003 Aliberti J, Viola JP, Vieira-de-Abreu A, Bozza PT, Sher A, Scharfstein J. Cutting edge: bradykinin induces IL-12 production by dendritic cells: a danger signal that drives Th1 polarization. Journal of Immunology (Baltimore, Md. : 1950). 170: 5349-53. PMID 12759407 DOI: 10.4049/Jimmunol.170.11.5349  0.346
2003 Sanderson SJ, Westrop GD, Scharfstein J, Mottram JC, Coombs GH. Functional conservation of a natural cysteine peptidase inhibitor in protozoan and bacterial pathogens. Febs Letters. 542: 12-6. PMID 12729889 DOI: 10.1016/S0014-5793(03)00327-2  0.338
2003 Mukherjee S, Huang H, Weiss LM, Costa S, Scharfstein J, Tanowitz HB. Role of vasoactive mediators in the pathogenesis of Chagas' disease. Frontiers in Bioscience : a Journal and Virtual Library. 8: e410-9. PMID 12700081 DOI: 10.2741/1103  0.359
2003 Todorov AG, Andrade D, Pesquero JB, Araujo Rde C, Bader M, Stewart J, Gera L, Müller-Esterl W, Morandi V, Goldenberg RC, Neto HC, Scharfstein J. Trypanosoma cruzi induces edematogenic responses in mice and invades cardiomyocytes and endothelial cells in vitro by activating distinct kinin receptor (B1/B2) subtypes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 73-5. PMID 12424228 DOI: 10.1096/Fj.02-0477Fje  0.352
2002 Schnapp AR, Eickhoff CS, Scharfstein J, Hoft DF. Induction of B- and T-cell responses to cruzipain in the murine model of Trypanosoma cruzi infection. Microbes and Infection / Institut Pasteur. 4: 805-13. PMID 12270727 DOI: 10.1016/S1286-4579(02)01600-3  0.384
2002 Lalmanach G, Boulangé A, Serveau C, Lecaille F, Scharfstein J, Gauthier F, Authié E. Congopain from Trypanosoma congolense: drug target and vaccine candidate. Biological Chemistry. 383: 739-49. PMID 12108538 DOI: 10.1515/Bc.2002.077  0.37
2002 Judice WA, Cezari MH, Lima AP, Scharfstein J, Chagas JR, Tersariol IL, Juliano MA, Juliano L. Comparison of the specificity, stability and individual rate constants with respective activation parameters for the peptidase activity of cruzipain and its recombinant form, cruzain, from Trypanosoma cruzi. European Journal of Biochemistry. 268: 6578-86. PMID 11737212 DOI: 10.1046/J.0014-2956.2001.02612.X  0.31
2001 Lima AP, dos Reis FC, Serveau C, Lalmanach G, Juliano L, Ménard R, Vernet T, Thomas DY, Storer AC, Scharfstein J. Cysteine protease isoforms from Trypanosoma cruzi, cruzipain 2 and cruzain, present different substrate preference and susceptibility to inhibitors. Molecular and Biochemical Parasitology. 114: 41-52. PMID 11356512 DOI: 10.1016/S0166-6851(01)00236-5  0.398
2000 Scharfstein J, Schmitz V, Morandi V, Capella MM, Lima AP, Morrot A, Juliano L, Müller-Esterl W. Host cell invasion by Trypanosoma cruzi is potentiated by activation of bradykinin B(2) receptors. The Journal of Experimental Medicine. 192: 1289-300. PMID 11067878 DOI: 10.1084/Jem.192.9.1289  0.395
2000 Yong V, Schmitz V, Vannier-Santos MA, de Lima AP, Lalmanach G, Juliano L, Gauthier F, Scharfstein J. Altered expression of cruzipain and a cathepsin B-like target in a Trypanosoma cruzi cell line displaying resistance to synthetic inhibitors of cysteine-proteinases. Molecular and Biochemical Parasitology. 109: 47-59. PMID 10924756 DOI: 10.1016/S0166-6851(00)00237-1  0.366
1999 Scharfstein J, Morrot A. A role for extracellular amastigotes in the immunopathology of Chagas disease Memorias Do Instituto Oswaldo Cruz. 94: 51-63. PMID 10677691 DOI: 10.1590/S0074-02761999000700005  0.378
1999 Serveau C, Lalmanach G, Hirata I, Scharfstein J, Juliano MA, Gauthier F. Discrimination of cruzipain, the major cysteine proteinase of Trypanosoma cruzi, and mammalian cathepsins B and L, by a pH-inducible fluorogenic substrate of trypanosomal cysteine proteinases. European Journal of Biochemistry. 259: 275-80. PMID 9914503 DOI: 10.1046/J.1432-1327.1999.00032.X  0.326
1998 Lalmanach G, Lecaille F, Chagas JR, Authié E, Scharfstein J, Juliano MA, Gauthier F. Inhibition of trypanosomal cysteine proteinases by their propeptides. The Journal of Biological Chemistry. 273: 25112-6. PMID 9737969 DOI: 10.1074/Jbc.273.39.25112  0.332
1998 Meldal M, Svendsen IB, Juliano L, Juliano MA, Nery ED, Scharfstein J. Inhibition of cruzipain visualized in a fluorescence quenched solid-phase inhibitor library assay. D-amino acid inhibitors for cruzipain, cathepsin B and cathepsin L. Journal of Peptide Science : An Official Publication of the European Peptide Society. 4: 83-91. PMID 9620612 DOI: 10.1002/(Sici)1099-1387(199804)4:2<83::Aid-Psc124>3.0.Co;2-Z  0.336
1997 Del Nery E, Juliano MA, Lima AP, Scharfstein J, Juliano L. Kininogenase activity by the major cysteinyl proteinase (cruzipain) from Trypanosoma cruzi. The Journal of Biological Chemistry. 272: 25713-8. PMID 9325296 DOI: 10.1074/Jbc.272.41.25713  0.343
1997 Nery ED, Juliano MA, Meldal M, Svendsen I, Scharfstein J, Walmsley A, Juliano L. Characterization of the substrate specificity of the major cysteine protease (cruzipain) from Trypanosoma cruzi using a portion-mixing combinatorial library and fluorogenic peptides. The Biochemical Journal. 427-33. PMID 9163334 DOI: 10.1042/Bj3230427  0.302
1996 Lalmanach G, Mayer R, Serveau C, Scharfstein J, Gauthier F. Biotin-labelled peptidyl diazomethane inhibitors derived from the substrate-like sequence of cystatin: targeting of the active site of cruzipain, the major cysteine proteinase of Trypanosoma cruzi. Biochemical Journal. 318: 395-399. PMID 8809025 DOI: 10.1042/Bj3180395  0.382
1996 Serveau C, Lalmanach G, Juliano MA, Scharfstein J, Juliano L, Gauthier F. Investigation of the substrate specificity of cruzipain, the major cysteine proteinase of Trypanosoma cruzi, through the use of cystatin-derived substrates and inhibitors. The Biochemical Journal. 951-6. PMID 8611180 DOI: 10.1042/Bj3130951  0.358
1995 Scharfstein J, Abrahamson M, Palatnik de Souza CB, Barral A, Silva IV. Antigenicity of cystatin-binding proteins from parasitic protozoan Detection by a proteinase inhibitor based capture immunoassay (PINC-ELISA) Journal of Immunological Methods. 182: 63-72. PMID 7769245 DOI: 10.1016/0022-1759(95)00023-4  0.376
1993 Gazzinelli RT, Galvao LM, Krautz G, Lima PC, Cancado JR, Scharfstein J, Krettli AU. Use of Trypanosoma cruzi purified glycoprotein (GP57/51) or trypomastigote-shed antigens to assess cure for human Chagas' disease. American Journal of Tropical Medicine and Hygiene. 49: 625-635. PMID 8250103 DOI: 10.4269/Ajtmh.1993.49.625  0.322
1993 Oliveira MM, Rocha ED, Rondinelli E, Arnholdt AV, Scharfstein J. Signal transduction in Trypanosoma cruzi: opposite effects of adenylcyclase and phospholipase C systems in growth control. Molecular and Cellular Biochemistry. 124: 91-9. PMID 8232289 DOI: 10.1007/Bf00929200  0.327
1992 Meirelles MN, Juliano L, Carmona E, Silva SG, Costa EM, Murta AC, Scharfstein J. Inhibitors of the major cysteinyl proteinase (GP57/51) impair host cell invasion and arrest the intracellular development of Trypanosoma cruzi in vitro. Molecular and Biochemical Parasitology. 52: 175-84. PMID 1620157 DOI: 10.1016/0166-6851(92)90050-T  0.401
1991 Bonaldo MC, Scharfstein J, Murta ACM, Goldenberg S. Further characterization of Trypanosoma cruzi GP57/51 as the major antigen expressed by differentiating epimastigotes. Parasitology Research. 77: 567-571. PMID 1792225 DOI: 10.1007/Bf00931014  0.314
1991 Bellio M, Leal LMC, Scharfstein J, Reis GAD. Interactions between CD3 and THY1 T cell activation pathways: Blockade of CD3-mediated T lymphocyte activation induced by immobilized anti-THY1 antibodies Cellular Immunology. 135: 534-540. PMID 1674673 DOI: 10.1016/0008-8749(91)90296-N  0.312
1990 Gazzinelli RT, Leme VMC, Cançado JR, Gazzinelli G, Scharfstein J. Identification and partial characterization of Trypanosoma cruzi antigens recognized by T cells and immune sera from patients with Chagas' disease. Infection and Immunity. 58: 1437-1444. PMID 2108932 DOI: 10.1128/Iai.58.5.1437-1444.1990  0.36
1990 Murta ACM, Persechini PM, Padrón TdS, Souza Wd, Guimarães JA, Scharfstein J. Structural and functional identification of GP57/51 antigen of Trypanosoma cruzi as a cysteine proteinase. Molecular and Biochemical Parasitology. 43: 27-38. PMID 1705310 DOI: 10.1016/0166-6851(90)90127-8  0.393
1988 Gazzinelli RT, Leme VMC, Cançado JR, Gazzinelli G, Scharfstein J. Identification of Trypanosoma cruzi antigens recognized by T cells and immune sera from chagasic patients Memorias Do Instituto Oswaldo Cruz. 83: 272-279. PMID 3150992 DOI: 10.1590/S0074-02761988000500010  0.328
1988 Murta ACM, Leme VCM, Milani SR, Travassos LR, Scharfstein J. Glycoprotein GP57/51 of Trypanosoma cruzi: structural and conformational epitopes defined with monoclonal antibodies Memorias Do Instituto Oswaldo Cruz. 83: 419-422. PMID 2473380 DOI: 10.1590/S0074-02761988000500038  0.48
1985 Scharfstein J, Luquetti A, Murta ACM, Senna M, Rezende JM, Rassi A, Mendonça-Previato L. Chagas' disease: serodiagnosis with purified Gp25 antigen. American Journal of Tropical Medicine and Hygiene. 34: 1153-1160. PMID 3938927 DOI: 10.4269/Ajtmh.1985.34.1153  0.303
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