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Joachim Frank - Publications

Affiliations: 
Biochemistry and Molecular Biophysics Columbia University, New York, NY 
Area:
cryo-electron microscopy (cryo-EM) of ribosomes
Website:
http://biochemistry.hs.columbia.edu/faculty/joachim.html
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309 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Park J, Zuo H, Frangaj A, Fu Z, Yen LY, Zhang Z, Mosyak L, Slavkovich VN, Liu J, Ray KM, Cao B, Vallese F, Geng Y, Chen S, Grassucci R, ... ... Frank J, et al. Symmetric activation and modulation of the human calcium-sensing receptor. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34916296 DOI: 10.1073/pnas.2115849118  0.711
2020 Dashti A, Mashayekhi G, Shekhar M, Ben Hail D, Salah S, Schwander P, des Georges A, Singharoy A, Frank J, Ourmazd A. Retrieving functional pathways of biomolecules from single-particle snapshots. Nature Communications. 11: 4734. PMID 32948759 DOI: 10.1038/S41467-020-18403-X  0.747
2020 Washburn RS, Zuber PK, Sun M, Hashem Y, Shen B, Li W, Harvey S, Acosta Reyes FJ, Gottesman ME, Knauer SH, Frank J. Escherichia coli NusG Links the Lead Ribosome with the Transcription Elongation Complex. Iscience. 23: 101352. PMID 32726726 DOI: 10.1016/J.Isci.2020.101352  0.379
2020 Park J, Fu Z, Frangaj A, Liu J, Mosyak L, Shen T, Slavkovich VN, Ray KM, Taura J, Cao B, Geng Y, Zuo H, Kou Y, Grassucci R, Chen S, ... ... Frank J, et al. Author Correction: Structure of human GABA receptor in an inactive state. Nature. PMID 32665714 DOI: 10.1038/S41586-020-2543-Y  0.716
2020 Park J, Fu Z, Frangaj A, Liu J, Mosyak L, Shen T, Slavkovich VN, Ray KM, Taura J, Cao B, Geng Y, Zuo H, Kou Y, Grassucci R, Chen S, ... ... Frank J, et al. Structure of human GABA receptor in an inactive state. Nature. PMID 32581365 DOI: 10.1038/S41586-020-2452-0  0.736
2020 Zheng X, Fu Z, Su D, Zhang Y, Li M, Pan Y, Li H, Li S, Grassucci RA, Ren Z, Hu Z, Li X, Zhou M, Li G, Frank J, et al. Mechanism of ligand activation of a eukaryotic cyclic nucleotide-gated channel. Nature Structural & Molecular Biology. PMID 32483338 DOI: 10.1038/S41594-020-0433-5  0.738
2020 Carter SD, Hampton CM, Langlois R, Melero R, Farino ZJ, Calderon MJ, Li W, Wallace CT, Tran NH, Grassucci RA, Siegmund SE, Pemberton J, Morgenstern TJ, Eisenman L, Aguilar JI, ... ... Frank J, et al. Ribosome-associated vesicles: A dynamic subcompartment of the endoplasmic reticulum in secretory cells. Science Advances. 6: eaay9572. PMID 32270040 DOI: 10.1126/Sciadv.Aay9572  0.77
2019 Acosta-Reyes F, Neupane R, Frank J, Fernández IS. The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. The Embo Journal. e102226. PMID 31609474 DOI: 10.15252/Embj.2019102226  0.363
2019 Fu Z, Indrisiunaite G, Kaledhonkar S, Shah B, Sun M, Chen B, Grassucci RA, Ehrenberg M, Frank J. The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy. Nature Communications. 10: 2579. PMID 31189921 DOI: 10.1016/J.Bpj.2018.11.3090  0.764
2019 Kaledhonkar S, Fu Z, Caban K, Li W, Chen B, Sun M, Gonzalez RL, Frank J. Late steps in bacterial translation initiation visualized using time-resolved cryo-EM. Nature. PMID 31108498 DOI: 10.1038/S41586-019-1249-5  0.752
2018 Qiu W, Fu Z, Xu GG, Grassucci RA, Zhang Y, Frank J, Hendrickson WA, Guo Y. Structure and activity of lipid bilayer within a membrane-protein transporter. Proceedings of the National Academy of Sciences of the United States of America. 115: 12985-12990. PMID 30509977 DOI: 10.1073/pnas.1812526115  0.733
2018 Gerbasi VR, Browne CM, Samir P, Shen B, Sun M, Hazelbaker DZ, Galassie AC, Frank J, Link AJ. Critical Role for Saccharomyces cerevisiae Asc1p in Translational Initiation at Elevated Temperatures. Proteomics. e1800208. PMID 30285306 DOI: 10.1002/Pmic.201800208  0.325
2018 Wang J, Liu Z, Crabtree RH, Frank J, Moore PB. On the damage done to the structure of the T. acidophilum proteasome by electron radiation. Protein Science : a Publication of the Protein Society. PMID 30242932 DOI: 10.1002/Pro.3511  0.336
2018 Samir P, Brown CM, Rahul R, Sun M, Shen B, Li W, Frank J, Link AJ. Identification of Changing Ribosome Protein Compositions using Mass Spectrometry. Proteomics. e1800217. PMID 30211483 DOI: 10.1002/Pmic.201800217  0.304
2018 Frank J. Single-Particle Reconstruction of Biological Molecules-Story in a Sample (Nobel Lecture). Angewandte Chemie (International Ed. in English). PMID 29978534 DOI: 10.1002/Anie.201802770  0.318
2018 Jobe A, Liu Z, Gutierrez-Vargas C, Frank J. New Insights into Ribosome Structure and Function. Cold Spring Harbor Perspectives in Biology. PMID 29903714 DOI: 10.1101/Cshperspect.A032615  0.368
2018 Fislage M, Zhang J, Brown ZP, Mandava CS, Sanyal S, Ehrenberg M, Frank J. Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A. Nucleic Acids Research. PMID 29733411 DOI: 10.1093/Nar/Gky346  0.358
2018 Kaledhonkar S, Fu Z, White H, Frank J. Time-Resolved Cryo-electron Microscopy Using a Microfluidic Chip. Methods in Molecular Biology (Clifton, N.J.). 1764: 59-71. PMID 29605908 DOI: 10.1007/978-1-4939-7759-8_4  0.749
2018 Hashem Y, Frank J. The Jigsaw Puzzle of mRNA Translation Initiation in Eukaryotes: A Decade of Structures Unraveling the Mechanics of the Process. Annual Review of Biophysics. PMID 29494255 DOI: 10.1146/Annurev-Biophys-070816-034034  0.33
2018 Santulli G, Lewis D, des Georges A, Marks AR, Frank J. Ryanodine Receptor Structure and Function in Health and Disease. Sub-Cellular Biochemistry. 87: 329-352. PMID 29464565 DOI: 10.1007/978-981-10-7757-9_11  0.727
2018 Caban K, Pavlov M, Kaledhonkar S, Fu Z, Frank J, Ehrenberg M, Gonzalez RL. The Structural Basis for Initiation Factor 2 Activation during Translation Initiation Biophysical Journal. 114: 593a. DOI: 10.1016/J.Bpj.2017.11.3243  0.738
2018 Qiu W, Fu Z, Xu G, Grassucci RA, Hendrickson WA, Zhang Y, Frank J, Guo Y. Lipid Bilayer Structure in Native Cell Membrane Nanoparticles of Multidrug Exporter ACRB Biophysical Journal. 114: 369a-370a. DOI: 10.1016/J.Bpj.2017.11.2048  0.71
2017 Twomey EC, Yelshanskaya MV, Grassucci RA, Frank J, Sobolevsky AI. Channel opening and gating mechanism in AMPA-subtype glutamate receptors. Nature. PMID 28737760 DOI: 10.1038/Nature23479  0.773
2017 Frank J. Time-resolved Cryo-Electron Microscopy: Recent Progress. Journal of Structural Biology. PMID 28625887 DOI: 10.1016/J.Jsb.2017.06.005  0.332
2017 Twomey EC, Yelshanskaya MV, Grassucci RA, Frank J, Sobolevsky AI. Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes. Neuron. 94: 569-580.e5. PMID 28472657 DOI: 10.1016/J.Neuron.2017.04.025  0.802
2017 Frank J. The mechanism of translation. F1000research. 6: 198. PMID 28344776 DOI: 10.12688/F1000Research.9760.1  0.372
2017 Feng X, Fu Z, Kaledhonkar S, Jia Y, Shah B, Jin A, Liu Z, Sun M, Chen B, Grassucci RA, Ren Y, Jiang H, Frank J, Lin Q. A Fast and Effective Microfluidic Spraying-Plunging Method for High-Resolution Single-Particle Cryo-EM. Structure (London, England : 1993). PMID 28286002 DOI: 10.1016/J.Str.2017.02.005  0.734
2017 Maji S, Shahoei R, Schulten K, Frank J. Quantitative Characterization of Domain Motions in Molecular Machines. The Journal of Physical Chemistry. B. PMID 28199113 DOI: 10.1021/Acs.Jpcb.6B10732  0.453
2017 Malyutin AG, Musalgaonkar S, Patchett S, Frank J, Johnson AW. Nmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome biogenesis. The Embo Journal. PMID 28179369 DOI: 10.15252/Embj.201696012  0.396
2017 Frank J. The translation elongation cycle-capturing multiple states by cryo-electron microscopy. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 372. PMID 28138066 DOI: 10.1098/Rstb.2016.0180  0.376
2017 Frank J. Advances in the field of single-particle cryo-electron microscopy over the last decade. Nature Protocols. 12: 209-212. PMID 28055037 DOI: 10.1038/Nprot.2017.004  0.359
2017 Georges Ad, Clarke OB, Zalk R, Yuan Q, Condon KJ, Grassucci RA, Hendrickson WA, Marks AR, Frank J. Functional Study of the Ryanodine Receptor Type 1 using Cryo-Electron Microscopy Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.1813  0.384
2016 Fu Z, Kaledhonkar S, Borg A, Sun M, Chen B, Grassucci RA, Ehrenberg M, Frank J. Key Intermediates in Ribosome Recycling Visualized by Time-Resolved Cryoelectron Microscopy. Structure (London, England : 1993). PMID 27818103 DOI: 10.1016/J.Str.2016.09.014  0.768
2016 Liu Z, Gutierrez-Vargas C, Wei J, Grassucci RA, Ramesh M, Espina N, Sun M, Tutuncuoglu B, Madison-Antenucci S, Woolford JL, Tong L, Frank J. Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit. Proceedings of the National Academy of Sciences of the United States of America. 113: 12174-12179. PMID 27791004 DOI: 10.1073/Pnas.1614594113  0.39
2016 Liu Z, Gutierrez-Vargas C, Wei J, Grassucci RA, Espina N, Madison-Antenucci S, Tong L, Frank J. Determination of the ribosome structure to a resolution of 2.5 Å by single-particle cryo-EM. Protein Science : a Publication of the Protein Society. PMID 27750394 DOI: 10.1002/Pro.3068  0.365
2016 des Georges A, Clarke OB, Zalk R, Yuan Q, Condon KJ, Grassucci RA, Hendrickson WA, Marks AR, Frank J. Structural Basis for Gating and Activation of RyR1. Cell. 167: 145-157.e17. PMID 27662087 DOI: 10.1016/J.Cell.2016.08.075  0.734
2016 Chen Y, Clarke OB, Kim J, Stowe S, Kim YK, Assur Z, Cavalier M, Godoy-Ruiz R, von Alpen DC, Manzini C, Blaner WS, Frank J, Quadro L, Weber DJ, Shapiro L, et al. Structure of the STRA6 receptor for retinol uptake. Science (New York, N.Y.). 353. PMID 27563101 DOI: 10.1126/Science.Aad8266  0.343
2016 Twomey EC, Yelshanskaya MV, Grassucci RA, Frank J, Sobolevsky AI. Elucidation of AMPA receptor-stargazin complexes by cryo-electron microscopy. Science (New York, N.Y.). 353: 83-6. PMID 27365450 DOI: 10.1126/Science.Aaf8411  0.797
2016 Frank J. Whither ribosome structure and dynamics research? (A Perspective). Journal of Molecular Biology. PMID 27178840 DOI: 10.1016/J.Jmb.2016.04.034  0.356
2016 Frank J, Ourmazd A. Continuous Changes in Structure Mapped by Manifold Embedding of Single-Particle Data in Cryo-EM. Methods (San Diego, Calif.). PMID 26884261 DOI: 10.1016/J.Ymeth.2016.02.007  0.375
2015 Chen B, Frank J. Two promising future developments of cryo-EM: capturing short-lived states and mapping a continuum of states of a macromolecule. Microscopy (Oxford, England). PMID 26520784 DOI: 10.1093/Jmicro/Dfv344  0.3
2015 Sun M, Li W, Blomqvist K, Das S, Hashem Y, Dvorin JD, Frank J. Dynamical features of the Plasmodium falciparum ribosome during translation. Nucleic Acids Research. PMID 26432834 DOI: 10.1093/Nar/Gkv991  0.347
2015 des Georges A, Dhote V, Kuhn L, Hellen CU, Pestova TV, Frank J, Hashem Y. Structure of mammalian eIF3 in the context of the 43S preinitiation complex. Nature. 525: 491-5. PMID 26344199 DOI: 10.1038/Nature14891  0.771
2015 Li W, Liu Z, Koripella RK, Langlois R, Sanyal S, Frank J. Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G. Science Advances. 1. PMID 26229983 DOI: 10.1126/Sciadv.1500169  0.361
2015 Chen B, Kaledhonkar S, Sun M, Shen B, Lu Z, Barnard D, Lu TM, Gonzalez RL, Frank J. Structural dynamics of ribosome subunit association studied by mixing-spraying time-resolved cryogenic electron microscopy. Structure (London, England : 1993). 23: 1097-105. PMID 26004440 DOI: 10.1016/J.Str.2015.04.007  0.373
2015 Liao HY, Hashem Y, Frank J. Efficient estimation of three-dimensional covariance and its application in the analysis of heterogeneous samples in cryo-electron microscopy. Structure (London, England : 1993). 23: 1129-37. PMID 25982529 DOI: 10.1016/J.Str.2015.04.004  0.365
2015 Marabini R, Carragher B, Chen S, Chen J, Cheng A, Downing KH, Frank J, Grassucci RA, Bernard Heymann J, Jiang W, Jonic S, Liao HY, Ludtke SJ, Patwari S, Piotrowski AL, et al. CTF Challenge: Result summary. Journal of Structural Biology. 190: 348-59. PMID 25913484 DOI: 10.1016/J.Jsb.2015.04.003  0.778
2015 Kinz-Thompson CD, Sharma AK, Frank J, Gonzalez RL, Chowdhury D. Quantitative Connection between Ensemble Thermodynamics and Single-Molecule Kinetics: A Case Study Using Cryogenic Electron Microscopy and Single-Molecule Fluorescence Resonance Energy Transfer Investigations of the Ribosome. The Journal of Physical Chemistry. B. PMID 25785884 DOI: 10.1021/Jp5128805  0.311
2015 Zalk R, Clarke OB, des Georges A, Grassucci RA, Reiken S, Mancia F, Hendrickson WA, Frank J, Marks AR. Structure of a mammalian ryanodine receptor. Nature. 517: 44-9. PMID 25470061 DOI: 10.1038/Nature13950  0.737
2014 Dashti A, Schwander P, Langlois R, Fung R, Li W, Hosseinizadeh A, Liao HY, Pallesen J, Sharma G, Stupina VA, Simon AE, Dinman JD, Frank J, Ourmazd A. Trajectories of the ribosome as a Brownian nanomachine. Proceedings of the National Academy of Sciences of the United States of America. 111: 17492-7. PMID 25422471 DOI: 10.1073/Pnas.1419276111  0.591
2014 Langlois R, Pallesen J, Ash JT, Nam Ho D, Rubinstein JL, Frank J. Automated particle picking for low-contrast macromolecules in cryo-electron microscopy. Journal of Structural Biology. 186: 1-7. PMID 24607413 DOI: 10.1016/J.Jsb.2014.03.001  0.339
2014 Boël G, Smith PC, Ning W, Englander MT, Chen B, Hashem Y, Testa AJ, Fischer JJ, Wieden HJ, Frank J, Gonzalez RL, Hunt JF. The ABC-F protein EttA gates ribosome entry into the translation elongation cycle. Nature Structural & Molecular Biology. 21: 143-51. PMID 24389466 DOI: 10.1038/Nsmb.2740  0.31
2014 Chen B, Boël G, Hashem Y, Ning W, Fei J, Wang C, Gonzalez RL, Hunt JF, Frank J. EttA regulates translation by binding the ribosomal E site and restricting ribosome-tRNA dynamics. Nature Structural & Molecular Biology. 21: 152-9. PMID 24389465 DOI: 10.1038/Nsmb.2741  0.353
2014 des Georges A, Hashem Y, Unbehaun A, Grassucci RA, Taylor D, Hellen CU, Pestova TV, Frank J. Structure of the mammalian ribosomal pre-termination complex associated with eRF1.eRF3.GDPNP. Nucleic Acids Research. 42: 3409-18. PMID 24335085 DOI: 10.1093/Nar/Gkt1279  0.796
2014 Jobe A, Ruehle MD, Kieft JS, Frank J. A CRYO-EM Structure of a Minimal Translation Initiation System: Deletion in Self-Sufficient IRES Prevents Translocation Biophysical Journal. 106: 601a. DOI: 10.1016/J.Bpj.2013.11.3326  0.384
2014 Chen B, Sun M, Shen B, Lu Z, Barnard D, Lu T, Gonzalez R, Frank J. A Time-Resolved CRYO-EM Study of Ribosome Subunit Association by Mixing-Spraying Biophysical Journal. 106: 5-8. DOI: 10.1016/J.Bpj.2013.11.3310  0.342
2014 Ho DN, Shaqra A, Li W, deLivron MA, Dionne G, Gao N, Robinson VL, Frank J. The Cryo-EM Structure of the Ribosome Bound to BipA Biophysical Journal. 106: 492a. DOI: 10.1016/J.Bpj.2013.11.2752  0.386
2013 Hashem Y, des Georges A, Dhote V, Langlois R, Liao HY, Grassucci RA, Pestova TV, Hellen CU, Frank J. Hepatitis-C-virus-like internal ribosome entry sites displace eIF3 to gain access to the 40S subunit. Nature. 503: 539-43. PMID 24185006 DOI: 10.1038/Nature12658  0.733
2013 Lee SH, Ripke S, Neale BM, Faraone SV, Purcell SM, Perlis RH, Mowry BJ, Thapar A, Goddard ME, Witte JS, Absher D, Agartz I, Akil H, Amin F, ... ... Frank J, et al. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nature Genetics. 45: 984-94. PMID 23933821 DOI: 10.1038/Ng.2711  0.353
2013 Pallesen J, Hashem Y, Korkmaz G, Koripella RK, Huang C, Ehrenberg M, Sanyal S, Frank J. Cryo-EM visualization of the ribosome in termination complex with apo-RF3 and RF1. Elife. 2: e00411. PMID 23755360 DOI: 10.7554/Elife.00411  0.381
2013 Hashem Y, des Georges A, Dhote V, Langlois R, Liao HY, Grassucci RA, Hellen CU, Pestova TV, Frank J. Structure of the mammalian ribosomal 43S preinitiation complex bound to the scanning factor DHX29. Cell. 153: 1108-19. PMID 23706745 DOI: 10.1016/J.Cell.2013.04.036  0.776
2013 Frank J. Story in a sample-the potential (and limitations) of cryo-electron microscopy applied to molecular machines. Biopolymers. 99: 832-6. PMID 23640776 DOI: 10.1002/Bip.22274  0.323
2013 Li W, Atkinson GC, Thakor NS, Allas U, Lu CC, Chan KY, Tenson T, Schulten K, Wilson KS, Hauryliuk V, Frank J. Mechanism of tetracycline resistance by ribosomal protection protein Tet(O). Nature Communications. 4: 1477. PMID 23403578 DOI: 10.1038/Ncomms2470  0.455
2013 Hashem Y, des Georges A, Fu J, Buss SN, Jossinet F, Jobe A, Zhang Q, Liao HY, Grassucci RA, Bajaj C, Westhof E, Madison-Antenucci S, Frank J. High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome. Nature. 494: 385-9. PMID 23395961 DOI: 10.1038/Nature11872  0.773
2013 Sharma G, Pallesen J, Das S, Grassucci R, Langlois R, Hampton CM, Kelly DF, des Georges A, Frank J. Affinity grid-based cryo-EM of PKC binding to RACK1 on the ribosome. Journal of Structural Biology. 181: 190-4. PMID 23228487 DOI: 10.1016/J.Jsb.2012.11.006  0.741
2013 Jobe A, Hashem Y, Georges Ad, Fu J, Buss SN, Jossinet F, Zhang Q, Liao HY, Grassucci B, Bajaj C, Madison-Antenucci S, Westhof E, Frank J. 33 High-resolution cryo-EM structure of theTrypanosoma brucei80S: a unique eukaryotic ribosome Journal of Biomolecular Structure and Dynamics. 31: 20-20. DOI: 10.1080/07391102.2013.786465  0.367
2012 Taylor D, Unbehaun A, Li W, Das S, Lei J, Liao HY, Grassucci RA, Pestova TV, Frank J. Cryo-EM structure of the mammalian eukaryotic release factor eRF1-eRF3-associated termination complex. Proceedings of the National Academy of Sciences of the United States of America. 109: 18413-8. PMID 23091004 DOI: 10.1073/Pnas.1216730109  0.567
2012 Frank J. Intermediate states during mRNA-tRNA translocation. Current Opinion in Structural Biology. 22: 778-85. PMID 22906732 DOI: 10.1016/J.Sbi.2012.08.001  0.346
2012 Bussiere C, Hashem Y, Arora S, Frank J, Johnson AW. Integrity of the P-site is probed during maturation of the 60S ribosomal subunit Journal of Cell Biology. 197: 747-759. PMID 22689654 DOI: 10.1083/Jcb.201112131  0.315
2012 Agirrezabala X, Liao HY, Schreiner E, Fu J, Ortiz-Meoz RF, Schulten K, Green R, Frank J. Structural characterization of mRNA-tRNA translocation intermediates. Proceedings of the National Academy of Sciences of the United States of America. 109: 6094-9. PMID 22467828 DOI: 10.1073/Pnas.1201288109  0.524
2012 Henderson R, Sali A, Baker ML, Carragher B, Devkota B, Downing KH, Egelman EH, Feng Z, Frank J, Grigorieff N, Jiang W, Ludtke SJ, Medalia O, Penczek PA, Rosenthal PB, et al. Outcome of the first electron microscopy validation task force meeting. Structure (London, England : 1993). 20: 205-14. PMID 22325770 DOI: 10.1016/J.Str.2011.12.014  0.633
2012 Leith A, Baxter W, Frank J. Use of SPIDER and SPIRE in image reconstruction International Tables For Crystallography. DOI: 10.1107/97809553602060000874  0.324
2012 Ho DN, deLivron MA, Gao N, Robinson VL, Frank J. Toward a Cryo-Em Structure of the Ribosome Bound to BipA Biophysical Journal. 102: 69. DOI: 10.1016/J.Bpj.2011.11.406  0.38
2012 Sharma G, Stupina V, Pallesen J, Shapiro B, Simon A, Dinman J, Frank J. Cryo-Electron Microscopy (Cryo-EM) Structure of a Cap-Independent Translational Enhancer of the Turnip Crinkle Virus (TCV) Bound to the Eukaryotic Ribosome Biophysical Journal. 102: 393a. DOI: 10.1016/J.Bpj.2011.11.2147  0.647
2011 Fu J, Hashem Y, Wower J, Frank J. tmRNA on its way through the ribosome: two steps of resume, and what next? Rna Biology. 8: 586-90. PMID 21593606 DOI: 10.4161/Rna.8.4.15585  0.384
2011 Fu J, Munro JB, Blanchard SC, Frank J. Cryoelectron microscopy structures of the ribosome complex in intermediate states during tRNA translocation. Proceedings of the National Academy of Sciences of the United States of America. 108: 4817-21. PMID 21383139 DOI: 10.1073/Pnas.1101503108  0.375
2011 Agirrezabala X, Schreiner E, Trabuco LG, Lei J, Ortiz-Meoz RF, Schulten K, Green R, Frank J. Structural insights into cognate versus near-cognate discrimination during decoding. The Embo Journal. 30: 1497-507. PMID 21378755 DOI: 10.1038/Emboj.2011.58  0.569
2011 Li W, Trabuco LG, Schulten K, Frank J. Molecular dynamics of EF-G during translocation. Proteins. 79: 1478-86. PMID 21365677 DOI: 10.1002/Prot.22976  0.5
2011 Harrison OJ, Jin X, Hong S, Bahna F, Ahlsen G, Brasch J, Wu Y, Vendome J, Felsovalyi K, Hampton CM, Troyanovsky RB, Ben-Shaul A, Frank J, Troyanovsky SM, Shapiro L, et al. The extracellular architecture of adherens junctions revealed by crystal structures of type I cadherins. Structure (London, England : 1993). 19: 244-56. PMID 21300292 DOI: 10.1016/J.Str.2010.11.016  0.301
2011 Huang T, Shaikh TR, Gupta K, Contreras-Martin LM, Grassucci RA, Van Duyne GD, Frank J, Belfort M. The group II intron ribonucleoprotein precursor is a large, loosely packed structure Nucleic Acids Research. 39: 2845-2854. PMID 21131279 DOI: 10.1093/Nar/Gkq1202  0.362
2011 Liao HY, Langlois R, Frank J. Classification of Projections in Single Particle Electron Microscopy using Common Line Similarity Measure Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.3538  0.319
2011 Hashem Y, Fu J, Frank J. The First Atomic Model of the Transfer-Messenger RNA in the Resume State Biophysical Journal. 100: 4-5. DOI: 10.1016/J.Bpj.2010.12.2402  0.393
2010 Frank J. The Ribosome Comes Alive. Israel Journal of Chemistry. 50: 95-98. PMID 21072331 DOI: 10.1002/Ijch.201000010  0.383
2010 Fu J, Hashem Y, Wower I, Lei J, Liao HY, Zwieb C, Wower J, Frank J. Visualizing the transfer-messenger RNA as the ribosome resumes translation. The Embo Journal. 29: 3819-25. PMID 20940705 DOI: 10.1038/Emboj.2010.255  0.412
2010 Sengupta J, Bussiere C, Pallesen J, West M, Johnson AW, Frank J. Characterization of the nuclear export adaptor protein Nmd3 in association with the 60S ribosomal subunit. The Journal of Cell Biology. 189: 1079-86. PMID 20584915 DOI: 10.1083/Jcb.201001124  0.414
2010 Agirrezabala X, Frank J. From DNA to proteins via the ribosome: structural insights into the workings of the translation machinery. Human Genomics. 4: 226-37. PMID 20511136 DOI: 10.1186/1479-7364-4-4-226  0.339
2010 Frank J, Gonzalez RL. Structure and dynamics of a processive Brownian motor: the translating ribosome. Annual Review of Biochemistry. 79: 381-412. PMID 20235828 DOI: 10.1146/Annurev-Biochem-060408-173330  0.374
2010 Réblová K, Rázga F, Li W, Gao H, Frank J, Sponer J. Dynamics of the base of ribosomal A-site finger revealed by molecular dynamics simulations and Cryo-EM. Nucleic Acids Research. 38: 1325-40. PMID 19952067 DOI: 10.1093/Nar/Gkp1057  0.307
2010 Liao HY, Frank J. On Bootstrap Techniques For Classifying Projections in Single Particle Electron Microscopy Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.066  0.315
2009 Agirrezabala X, Frank J. Elongation in translation as a dynamic interaction among the ribosome, tRNA, and elongation factors EF-G and EF-Tu. Quarterly Reviews of Biophysics. 42: 159-200. PMID 20025795 DOI: 10.1017/S0033583509990060  0.375
2009 Frank J. Single-particle reconstruction of biological macromolecules in electron microscopy--30 years. Quarterly Reviews of Biophysics. 42: 139-58. PMID 20025794 DOI: 10.1017/S0033583509990059  0.333
2009 Taylor DJ, Devkota B, Huang AD, Topf M, Narayanan E, Sali A, Harvey SC, Frank J. Comprehensive molecular structure of the eukaryotic ribosome. Structure (London, England : 1993). 17: 1591-604. PMID 20004163 DOI: 10.1016/J.Str.2009.09.015  0.564
2009 Shi Y, Di Giammartino DC, Taylor D, Sarkeshik A, Rice WJ, Yates JR, Frank J, Manley JL. Molecular architecture of the human pre-mRNA 3' processing complex. Molecular Cell. 33: 365-76. PMID 19217410 DOI: 10.1016/J.Molcel.2008.12.028  0.542
2009 Villa E, Sengupta J, Trabuco LG, LeBarron J, Baxter WT, Shaikh TR, Grassucci RA, Nissen P, Ehrenberg M, Schulten K, Frank J. Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis. Proceedings of the National Academy of Sciences of the United States of America. 106: 1063-8. PMID 19122150 DOI: 10.1073/Pnas.0811370106  0.662
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2001 Gabashvili IS, Gregory ST, Valle M, Grassucci R, Worbs M, Wahl MC, Dahlberg AE, Frank J. The polypeptide tunnel system in the ribosome and its gating in erythromycin resistance mutants of L4 and L22. Molecular Cell. 8: 181-8. PMID 11511371 DOI: 10.1016/S1097-2765(01)00293-3  0.785
2001 Frank J. Cryo-electron microscopy as an investigative tool: The ribosome as an example Bioessays. 23: 725-732. PMID 11494321 DOI: 10.1002/Bies.1102  0.437
2001 Spahn CM, Blaha G, Agrawal RK, Penczek P, Grassucci RA, Trieber CA, Connell SR, Taylor DE, Nierhaus KH, Frank J. Localization of the ribosomal protection protein Tet(O) on the ribosome and the mechanism of tetracycline resistance. Molecular Cell. 7: 1037-45. PMID 11389850 DOI: 10.1016/S1097-2765(01)00238-6  0.647
2001 Spahn CM, Kieft JS, Grassucci RA, Penczek PA, Zhou K, Doudna JA, Frank J. Hepatitis C virus IRES RNA-induced changes in the conformation of the 40s ribosomal subunit. Science (New York, N.Y.). 291: 1959-62. PMID 11239155 DOI: 10.1126/Science.1058409  0.661
2001 McEwen BF, Barnard RM, Hsieh C, Frank J. Using Electron Tomography to Determine How Kinetochores Bind and Alter the Conformations of Microtubule Plus Ends Microscopy and Microanalysis. 7: 86-87. DOI: 10.1017/S1431927600026507  0.325
2000 VanLoock MS, Agrawal RK, Gabashvili IS, Qi L, Frank J, Harvey SC. Movement of the decoding region of the 16 S ribosomal RNA accompanies tRNA translocation. Journal of Molecular Biology. 304: 507-15. PMID 11099376 DOI: 10.1006/Jmbi.2000.4213  0.745
2000 Spahn CM, Penczek PA, Leith A, Frank J. A method for differentiating proteins from nucleic acids in intermediate-resolution density maps: cryo-electron microscopy defines the quaternary structure of the Escherichia coli 70S ribosome. Structure (London, England : 1993). 8: 937-48. PMID 10986461 DOI: 10.1016/S0969-2126(00)00185-4  0.66
2000 Wriggers W, Agrawal RK, Drew DL, McCammon A, Frank J. Domain motions of EF-G bound to the 70S ribosome: insights from a hand-shaking between multi-resolution structures. Biophysical Journal. 79: 1670-8. PMID 10969026 DOI: 10.1016/S0006-3495(00)76416-2  0.376
2000 Agrawal RK, Spahn CM, Penczek P, Grassucci RA, Nierhaus KH, Frank J. Visualization of tRNA movements on the Escherichia coli 70S ribosome during the elongation cycle. The Journal of Cell Biology. 150: 447-60. PMID 10931859 DOI: 10.1083/Jcb.150.3.447  0.643
2000 Frank J, Agrawal RK. A ratchet-like inter-subunit reorganization of the ribosome during translocation. Nature. 406: 318-322. PMID 10917535 DOI: 10.1038/35018597  0.392
2000 Frank J. The ribosome – a macromolecular machine par excellence Chemistry & Biology. 7. PMID 10873840 DOI: 10.1016/S1074-5521(00)00127-7  0.403
2000 Gomez-Lorenzo MG, Spahn CM, Agrawal RK, Grassucci RA, Penczek P, Chakraburtty K, Ballesta JP, Lavandera JL, Garcia-Bustos JF, Frank J. Three-dimensional cryo-electron microscopy localization of EF2 in the Saccharomyces cerevisiae 80S ribosome at 17.5 A resolution. The Embo Journal. 19: 2710-8. PMID 10835368 DOI: 10.1093/Emboj/19.11.2710  0.69
2000 Blaha G, Stelzl U, Spahn CM, Agrawal RK, Frank J, Nierhaus KH. Preparation of functional ribosomal complexes and effect of buffer conditions on tRNA positions observed by cryoelectron microscopy. Methods in Enzymology. 317: 292-309. PMID 10829287 DOI: 10.1016/S0076-6879(00)17021-1  0.681
2000 Gabashvili IS, Agrawal RK, Spahn CM, Grassucci RA, Svergun DI, Frank J, Penczek P. Solution structure of the E. coli 70S ribosome at 11.5 A resolution. Cell. 100: 537-49. PMID 10721991 DOI: 10.1016/S0092-8674(00)80690-X  0.808
2000 Penczek P, Spahn CMT, Agrawal RK, Gabashvili IS, Grassucci RA, Frank J. Advances in High Resolution Cryo-EM Studies: the Quartenary Structure of the 70S E.Coli Ribosome Revealed at 11.5Å Resolution. Microscopy and Microanalysis. 6: 262-263. DOI: 10.1017/S1431927600033808  0.722
1999 Spahn CM, Grassucci RA, Penczek P, Frank J. Direct three-dimensional localization and positive identification of RNA helices within the ribosome by means of genetic tagging and cryo-electron microscopy. Structure (London, England : 1993). 7: 1567-73. PMID 10647187 DOI: 10.1016/S0969-2126(00)88347-1  0.66
1999 Penczek P, Ban N, Grassucci RA, Agrawal RK, Frank J. Haloarcula marismortui 50S subunit-complementarity of electron microscopy and X-Ray crystallographic information. Journal of Structural Biology. 128: 44-50. PMID 10600557 DOI: 10.1006/Jsbi.1999.4157  0.302
1999 Frank J, Heagle AB, Agrawal RK. Animation of the dynamical events of the elongation cycle based on cryoelectron microscopy of functional complexes of the ribosome. Journal of Structural Biology. 128: 15-18. PMID 10600553 DOI: 10.1006/Jsbi.1999.4138  0.361
1999 Gabashvili IS, Agrawal RK, Grassucci R, Squires CL, Dahlberg AE, Frank J. Major rearrangements in the 70S ribosomal 3D structure caused by a conformational switch in 16S ribosomal RNA. The Embo Journal. 18: 6501-7. PMID 10562562 DOI: 10.1093/Emboj/18.22.6501  0.75
1999 Agrawal RK, Heagle AB, Penczek P, Grassucci RA, Frank J. EF-G-dependent GTP hydrolysis induces translocation accompanied by large conformational changes in the 70S ribosome. Nature Structural & Molecular Biology. 6: 643-647. PMID 10404220 DOI: 10.1038/10695  0.324
1999 Agrawal RK, Frank J. Structural studies of the translational apparatus Current Opinion in Structural Biology. 9: 215-221. PMID 10322215 DOI: 10.1016/S0959-440X(99)80031-1  0.36
1999 Agrawal RK, Lata RK, Frank J. Conformational variability in Escherichia coli 70S ribosome as revealed by 3D cryo-electron microscopy. The International Journal of Biochemistry & Cell Biology. 31: 243-254. PMID 10216957 DOI: 10.1016/S1357-2725(98)00149-6  0.406
1999 McCutcheon JP, Agrawal RK, Philips SM, Grassucci RA, Gerchman SE, Clemons WM, Ramakrishnan V, Frank J. Location of translational initiation factor IF3 on the small ribosomal subunit. Proceedings of the National Academy of Sciences of the United States of America. 96: 4301-6. PMID 10200257 DOI: 10.1073/Pnas.96.8.4301  0.419
1999 Agrawal RK, Penczek P, Grassucci RA, Burkhardt N, Nierhaus KH, Frank J. Effect of buffer conditions on the position of tRNA on the 70 S ribosome as visualized by cryoelectron microscopy. Journal of Biological Chemistry. 274: 8723-8729. PMID 10085112 DOI: 10.1074/Jbc.274.13.8723  0.324
1999 Gabashvili IS, Agrawal RK, Grassucci R, Frank J. Structure and structural variations of the Escherichia coli 30 S ribosomal subunit as revealed by three-dimensional cryo-electron microscopy. Journal of Molecular Biology. 286: 1285-91. PMID 10064696 DOI: 10.1006/Jmbi.1999.2538  0.762
1999 Manoj N, Srinivas VR, Surolia A, Vijayan M, Suguna K, Ravishankar R, Schwarzenbacher R, Zeth K, Diederichs, Kostner GM, Gries A, Laggner P, Prassl R, Madhusudan, Akamine P, ... ... Frank J, et al. Contributory presentations/posters Journal of Biosciences. 24: 33-198. DOI: 10.1007/Bf02989373  0.386
1998 Frank J. The ribosome - Structure and functional ligand-binding experiments using cryo-electron microscopy Journal of Structural Biology. 124: 142-150. PMID 10049802 DOI: 10.1006/Jsbi.1998.4071  0.426
1998 Ban N, Freeborn B, Nissen P, Penczek P, Grassucci RA, Sweet R, Frank J, Moore PB, Steitz TA. A 9 A resolution X-ray crystallographic map of the large ribosomal subunit. Cell. 93: 1105-15. PMID 9657144 DOI: 10.1016/S0092-8674(00)81455-5  0.352
1998 Malhotra A, Penczek P, Agrawal RK, Gabashvili IS, Grassucci RA, Jünemann R, Burkhardt N, Nierhaus KH, Frank J. Escherichia coli 70 S ribosome at 15 A resolution by cryo-electron microscopy: localization of fMet-tRNAfMet and fitting of L1 protein. Journal of Molecular Biology. 280: 103-16. PMID 9653034 DOI: 10.1006/Jmbi.1998.1859  0.797
1998 Agrawal RK, Penczek PA, Grassucci RA, Frank J. Visualization of elongation factor G on the Escherichia coli 70S ribosome: The mechanism of translocation Proceedings of the National Academy of Sciences of the United States of America. 95: 6134-6138. PMID 9600930 DOI: 10.1073/Pnas.95.11.6134  0.396
1998 Samsó M, Radermacher M, Frank J, Koonce MP. Structural characterization of a dynein motor domain. Journal of Molecular Biology. 276: 927-37. PMID 9566197 DOI: 10.1006/Jmbi.1997.1584  0.366
1998 Frank J, Agrawal RK. The movement of tRNA through the ribosome. Biophysical Journal. 74: 589-594. PMID 9449359 DOI: 10.1016/S0006-3495(98)77817-8  0.343
1998 Verschoor A, Warner JR, Srivastava S, Grassucci RA, Frank J. Three-dimensional structure of the yeast ribosome Nucleic Acids Research. 26: 655-661. PMID 9421530 DOI: 10.1093/Nar/26.2.655  0.392
1998 Frank J, Penczek P, Malhotra A, Gabashvili I, Grassucci R, Heagle A, Srivastava S, Burkhardt N, Jünemann R, Nierhaus KH, Agrawal RK. The Ribosome - Three-Dimensional Structure and Ligand-Binding Studies Microscopy and Microanalysis. 4: 962-963. DOI: 10.1017/S1431927600024934  0.715
1997 Beckmann R, Bubeck D, Grassucci R, Penczek P, Verschoor A, Blobel G, Frank J. Alignment of conduits for the nascent polypeptide chain in the ribosome-Sec61 complex. Science (New York, N.Y.). 278: 2123-6. PMID 9405348 DOI: 10.1126/Science.278.5346.2123  0.406
1997 Zhu J, Penczek PA, Schröder R, Frank J. Three-Dimensional Reconstruction with Contrast Transfer Function Correction from Energy-Filtered Cryoelectron Micrographs: Procedure and Application to the 70S Escherichia coli Ribosome Journal of Structural Biology. 118: 197-219. PMID 9169230 DOI: 10.1006/Jsbi.1997.3845  0.307
1997 Frank J. The ribosome at higher resolution--the donut takes shape. Current Opinion in Structural Biology. 7: 266-272. PMID 9094327 DOI: 10.1016/S0959-440X(97)80035-8  0.372
1997 Wadzack J, Burkhardt N, Jünemann R, Diedrich G, Nierhaus KH, Frank J, Penczek P, Meerwinck W, Schmitt M, Willumeit R, Stuhrmann HB. Direct localization of the tRNAs within the elongating ribosome by means of neutron scattering (proton-spin contrast-variation). Journal of Molecular Biology. 266: 343-56. PMID 9047368 DOI: 10.1006/Jmbi.1996.0788  0.316
1996 Lata KR, Agrawal RK, Penczek P, Grassucci R, Zhu J, Frank J. Three-dimensional reconstruction of the Escherichia coli 30 S ribosomal subunit in ice. Journal of Molecular Biology. 262: 43-52. PMID 8809178 DOI: 10.1006/Jmbi.1996.0497  0.326
1996 Marabini R, Vaquerizo C, Fernández JJ, Carazo JM, Engel A, Frank J. Proposal for a new distributed database of macromolecular and subcellular structures from different areas of microscopy. Journal of Structural Biology. 116: 161-5. PMID 8742739 DOI: 10.1006/Jsbi.1996.0026  0.753
1996 Verschoor A, Srivastava S, Grassucci R, Frank J. Native 3D structure of eukaryotic 80s ribosome: morphological homology with E. coli 70S ribosome. Journal of Cell Biology. 133: 495-505. PMID 8636226 DOI: 10.1083/Jcb.133.3.495  0.359
1996 Agrawal RK, Penczek PA, Grassucci RA, Li Y, Leith A, Nierhaus KH, Frank J. Direct Visualization of A-, P-, and E-Site Transfer RNAs in the Escherichia coli Ribosome Science. 271: 1000-1002. PMID 8584922 DOI: 10.1126/Science.271.5251.1000  0.346
1996 Liu W, Boisset N, Frank J. Estimation of variance distribution in three-dimensional reconstruction. II. Applications. Journal of the Optical Society of America. a, Optics, Image Science, and Vision. 12: 2628-35. PMID 7500222 DOI: 10.1364/Josaa.12.002628  0.663
1995 Frank J, Verschoor A, Li Y, Zhu J, Lata RK, Radermacher M, Penczek PA, Grassucci R, Agrawal RK, Srivastava S. A Model Of The Translational Apparatus Based On A Three-Dimensional Reconstruction Of The Escherichia Coli Ribosome Biochemistry and Cell Biology. 73: 757-765. PMID 8721992 DOI: 10.1139/O95-084  0.337
1995 Srivastava S, Verschoor A, Radermacher M, Grassucci R, Frank J. Three-dimensional reconstruction of mammalian 40 S ribosomal subunit embedded in ice. Journal of Molecular Biology. 245: 461-466. PMID 7844819 DOI: 10.1006/Jmbi.1994.0037  0.373
1995 Frank J. Approaches to large-scale structures Current Opinion in Structural Biology. 5: 194-201. PMID 7648321 DOI: 10.1016/0959-440X(95)80075-1  0.328
1995 Frank J, Zhu J, Penczek PA, Li Y, Srivastava S, Verschoor A, Radermacher M, Grassucci R, Lata RK, Agrawal RK. A model of protein synthesis based on cryo-electron microscopy of the E. coli ribosome Nature. 376: 441-444. PMID 7630422 DOI: 10.1038/376441A0  0.41
1995 Boisset N, Penczek PA, Taveau JC, Lamy J, Frank J, Lamy J. Three-dimensional reconstruction of Androctonus australis hemocyanin labeled with a monoclonal Fab fragment. Journal of Structural Biology. 115: 16-29. PMID 7577229 DOI: 10.1006/Jsbi.1995.1025  0.665
1995 Lata KR, Penczek PA, Frank J. Automatic particle picking from electron micrographs. Ultramicroscopy. 58: 381-391. PMID 7571118 DOI: 10.1016/0304-3991(95)00002-I  0.301
1994 Mannella CA, Marko M, Penczek P, Barnard D, Frank J. The internal compartmentation of rat-liver mitochondria: Tomographic study using the high-voltage transmission electron microscope Microscopy Research and Technique. 27: 278-283. PMID 8186446 DOI: 10.1002/Jemt.1070270403  0.594
1994 Penczek PA, Grassucci RA, Frank J. The ribosome at improved resolution: new techniques for merging and orientation refinement in 3D cryo-electron microscopy of biological particles. Ultramicroscopy. 53: 251-270. PMID 8160308 DOI: 10.1016/0304-3991(94)90038-8  0.356
1994 Lambert O, Boisset N, Penczek PA, Lamy J, Taveau JC, Frank J, Lamy JN. Quaternary structure of Octopus vulgaris hemocyanin. Three-dimensional reconstruction from frozen-hydrated specimens and intramolecular location of functional units Ove and Ovb. Journal of Molecular Biology. 238: 75-87. PMID 8145258 DOI: 10.1006/Jmbi.1994.1269  0.67
1994 Radermacher M, Rao V, Grassucci R, Frank J, Timerman AP, Fleischer S, Wagenknecht T. Cryo-electron microscopy and three-dimensional reconstruction of the calcium release channel/ryanodine receptor from skeletal muscle Journal of Cell Biology. 127: 411-423. PMID 7929585 DOI: 10.1083/Jcb.127.2.411  0.345
1994 Boisset N, Penczek P, Pochon F, Frank J, Lamy J. Three‐Dimensional Reconstruction of Human α2‐Macroglobulin and Refinement of the Localization of Thiol Ester Bonds with Monomaleimido Nanogolda Annals of the New York Academy of Sciences. 737: 229-244. PMID 7524399 DOI: 10.1111/J.1749-6632.1994.Tb44315.X  0.614
1993 Frank J, Chiu W, Henderson R. Flopping polypeptide chains and Suleika's subtle imperfections: analysis of variations in the electron micrograph of a purple membrane crystal. Ultramicroscopy. 49: 387-96. PMID 8475603 DOI: 10.1016/0304-3991(93)90244-R  0.465
1993 McEwen BF, Arena JT, Frank J, Rieder CL. Structure of the colcemid-treated PtK1 kinetochore outer plate as determined by high voltage electron microscopic tomography. The Journal of Cell Biology. 120: 301-12. PMID 8421050 DOI: 10.1083/Jcb.120.2.301  0.304
1993 Boisset N, Radermacher M, Grassucci R, Taveau J, Liu W, Lamy J, Frank J, Lamy JN. Three-dimensional immunoelectron microscopy of scorpion hemocyanin labeled with a monoclonal Fab fragment. Journal of Structural Biology. 111: 234-244. PMID 8003384 DOI: 10.1006/Jsbi.1993.1053  0.669
1993 Boisset N, Penczek P, Pochon F, Frank J, Lamy J. Three-dimensional Architecture of Human α2-Macroglobulin Transformed with Methylamine Journal of Molecular Biology. 232: 522-529. PMID 7688427 DOI: 10.1006/Jmbi.1993.1408  0.65
1992 Srivastava S, Verschoor A, Frank J. Eukaryotic initiation factor 3 does not prevent association through physical blockage of the ribosomal subunit-subunit interface Journal of Molecular Biology. 226: 301-304. PMID 1640449 DOI: 10.1016/0022-2836(92)90946-H  0.354
1992 Morgan DG, Grant RA, Chiu W, Frank J. Patch averaging of electron images of GP32*I crystals with variable thickness Journal of Structural Biology. 108: 245-256. PMID 1335748 DOI: 10.1016/1047-8477(92)90025-6  0.453
1992 Radermacher M, Wagenknecht T, Grassucci R, Frank J, Iniu M, Chadwick C, Fleischer S. Cryo-EM of the native structure of the calcium release channel/ryanodine receptor from sarcoplasmic reticulum Biophysical Journal. 61: 936-940. PMID 1316182 DOI: 10.1016/S0006-3495(92)81900-8  0.31
1992 Boisset N, Grassucci R, Penczek P, Delain E, Pochon F, Frank J, Lamy JN. Three-dimensional reconstruction of a complex of human α2-macroglobulin with monomaleimido nanogold (Au1.4nm) embedded in ice Journal of Structural Biology. 109: 39-45. PMID 1283687 DOI: 10.1016/1047-8477(92)90065-I  0.654
1992 Penczek PA, Radermacher M, Frank J. Three-dimensional reconstruction of single particles embedded in ice. Ultramicroscopy. 40: 33-53. DOI: 10.1016/0304-3991(92)90233-A  0.31
1991 Frank J, Penczek P, Grassucci R, Srivastava S. Three-dimensional reconstruction of the 70S Escherichia coli ribosome in ice: the distribution of ribosomal RNA. Journal of Cell Biology. 115: 597-605. PMID 1918155 DOI: 10.1083/Jcb.115.3.597  0.388
1990 Verschoor A, Frank J. Three-dimensional structure of the mammalian cytoplasmic ribosome. Journal of Molecular Biology. 214: 737-749. PMID 2388265 DOI: 10.1016/0022-2836(90)90289-X  0.401
1990 Boisset N, Taveau JC, Lamy J, Wagenknecht T, Radermacher M, Frank J. Three-dimensional reconstruction of native Androctonus australis hemocyanin Journal of Molecular Biology. 216: 743-760. PMID 2258938 DOI: 10.1016/0022-2836(90)90396-4  0.663
1990 Carazo JM, Rivera FF, Zapata EL, Radermacher M, Frank J. Fuzzy sets-based classification of electron microscopy images of biological macromolecules with an application to ribosomal particles. Journal of Microscopy. 157: 187-203. PMID 2179560 DOI: 10.1111/J.1365-2818.1990.Tb02958.X  0.646
1989 Frank J, Chiu W, Degn L. The characterization of structural variations within a crystal field. Ultramicroscopy. 26: 345-60. PMID 3238812 DOI: 10.1016/0304-3991(88)90234-3  0.451
1989 Verschoor A, Zhang NY, Wagenknecht T, Obrig T, Radermacher M, Frank J. Three-dimensional reconstruction of mammalian 40 S ribosomal subunit Journal of Molecular Biology. 209: 115-126. PMID 2810364 DOI: 10.1016/0022-2836(89)90175-7  0.38
1989 Carazo JM, Wagenknecht T, Frank J. Variations of the three-dimensional structure of the Escherichia coli ribosome in the range of overlap views. An application of the methods of multicone and local single-cone three-dimensional reconstruction Biophysical Journal. 55: 465-477. PMID 2649164 DOI: 10.1016/S0006-3495(89)82840-1  0.697
1989 Wagenknecht T, Carazo JM, Radermacher M, Frank J. Three-dimensional reconstruction of the ribosome from Escherichia coli Biophysical Journal. 55: 455-464. PMID 2649163 DOI: 10.1016/S0006-3495(89)82839-5  0.71
1989 Wagenknecht T, Grassucci R, Frank J, Saito A, Inui M, Fleischer S. Three-dimensional architecture of the calcium channel/foot structure of sarcoplasmic reticulum Nature. 338: 167-170. PMID 2537473 DOI: 10.1038/338167A0  0.313
1989 Frank J. Image analysis of single macromolecules Electron Microscopy Reviews. 2: 53-74. PMID 2491342 DOI: 10.1016/0892-0354(89)90010-5  0.367
1988 Carazo JM, Frank J. Three-dimensional matching of macromolecular structures obtained from electron microscopy: an application to the 70S and 50S E. coli ribosomal particles. Ultramicroscopy. 25: 13-22. PMID 3291355 DOI: 10.1016/0304-3991(88)90401-9  0.694
1988 Frank J, Verschoor A, Wagenknecht T, Radermacher M, Carazo JM. A new non-crystallographic image-processing technique reveals the architecture of ribosomes Trends in Biochemical Sciences. 13: 123-127. PMID 3075375 DOI: 10.1016/0968-0004(88)90063-1  0.703
1988 Frank J, Radermacher M, Wagenknecht T, Verschoor A. Studying ribosome structure by electron microscopy and computer-image processing Methods in Enzymology. 164: 3-35. PMID 3071670 DOI: 10.1016/S0076-6879(88)64032-8  0.394
1988 Wagenknecht T, Frank J, Boublik M, Nurse K, Ofengand J. Direct localization of the tRNA-anticodon interaction site on the Escherichia coli 30 S ribosomal subunit by electron microscopy and computerized image averaging Journal of Molecular Biology. 203: 753-760. PMID 3062179 DOI: 10.1016/0022-2836(88)90207-0  0.404
1988 Carazo JM, Wagenknecht T, Radermacher M, Mandiyan V, Boublik M, Frank J. Three-dimensional structure of 50 S Escherichia coli ribosomal subunits depleted of proteins L7/L12 Journal of Molecular Biology. 201: 393-404. PMID 3047401 DOI: 10.1016/0022-2836(88)90146-5  0.711
1988 Frank J, Bretaudiere JP, Carazo JM, Verschoor A, Wagenknecht T. Classification of images of biomolecular assemblies: a study of ribosomes and ribosomal subunits of Escherichia coli Journal of Microscopy. 150. PMID 3045323 DOI: 10.1111/J.1365-2818.1988.Tb04602.X  0.684
1988 Boisset N, Frank J, Taveau JC, Billiald P, Motta G, Lamy J, Sizaret PY, Lamy J. Intermolecular localization of epitopes within an oligomeric protein by immunoelectron microscopy and image processing Proteins. 3: 161-183. PMID 2474818 DOI: 10.1002/Prot.340030305  0.678
1988 Saito A, Inui M, Radermacher M, Frank J, Fleischer S. Ultrastructure of the calcium release channel of sarcoplasmic reticulum. Journal of Cell Biology. 107: 211-219. PMID 2455723 DOI: 10.1083/Jcb.107.1.211  0.335
1988 Wagenknecht T, Grassucci R, Frank J. Electron microscopy and computer image averaging of ice-embedded large ribosomal subunits from Escherichia coli Journal of Molecular Biology. 199: 137-147. PMID 2451023 DOI: 10.1016/0022-2836(88)90384-1  0.397
1987 Radermacher M, Wagenknecht T, Verschoor A, Frank J. Three-dimensional reconstruction from a single-exposure, random conical tilt series applied to the 50S ribosomal subunit of Escherichia coli Journal of Microscopy. 146. PMID 3302267 DOI: 10.1111/J.1365-2818.1987.Tb01333.X  0.344
1987 Mannella CA, Frank J, Delihas N. Interrelatedness of 5S RNA sequences investigated by correspondence analysis. Journal of Molecular Evolution. 24: 228-235. PMID 3106638 DOI: 10.1007/Bf02111236  0.572
1987 Mannella CA, Ribeiro AJ, Frank J. Cytochrome c binds to lipid domains in arrays of mitochondrial outer membrane channels. Biophysical Journal. 51: 221-6. PMID 3030457 DOI: 10.1016/S0006-3495(87)83327-1  0.571
1987 Frank J, McEwen BF, Radermacher M, Turner JN, Rieder CL. Three-dimensional tomographic reconstruction in high voltage electron microscopy Journal of Electron Microscopy Technique. 6: 193-205. DOI: 10.1002/Jemt.1060060210  0.31
1987 Radermacher M, Wagenknecht T, Verschoor A, Frank J. Three-dimensional structure of the large ribosomal subunit from Escherichia coli. The Embo Journal. 6: 1107-1114. DOI: 10.1002/J.1460-2075.1987.Tb04865.X  0.432
1986 Frank J, Verschoor A, Wagenknecht T, Radermacher M, Rosenthal M, Boublik M. New strategies for determining ribosomal subunit structure from electron micrographs by single particle averaging methods. Biophysical Journal. 49: 9-11. PMID 19431662 DOI: 10.1016/S0006-3495(86)83571-8  0.369
1986 Mannella CA, Ribeiro A, Frank J. Structure of the Channels in the Outer Mitochondrial Membrane: Electron Microscopic Studies of the Periodic Arrays Induced by Phospholipase a2 Treatment of the Neurospora membrane Biophysical Journal. 49: 307-318. PMID 19431637 DOI: 10.1016/S0006-3495(86)83643-8  0.583
1986 Verschoor A, Frank J, Wagenknecht T, Boublik M. Computer-averaged views of the 70 S monosome from Escherichia coli Journal of Molecular Biology. 187: 581-590. PMID 3519978 DOI: 10.1016/0022-2836(86)90336-0  0.304
1986 McEwen BF, Radermacher M, Rieder CL, Frank J. Tomographic three-dimensional reconstruction of cilia ultrastructure from thick sections. Proceedings of the National Academy of Sciences of the United States of America. 83: 9040-9044. PMID 3466176 DOI: 10.1073/Pnas.83.23.9040  0.318
1986 Mannella CA, Frank J. Effect of succinylation on images of negatively stained arrays of mitochondrial outer membrane channels. Journal of Ultrastructure and Molecular Structure Research. 96: 31-40. PMID 2445865 DOI: 10.1016/0889-1605(86)90005-4  0.561
1986 Tsuji M, Frank J, Manley RSJ. Image analysis in the electron microscopy of cellulose protofibrils. II: Digital correlation methods Colloid and Polymer Science. 264: 89-96. DOI: 10.1007/Bf01410311  0.334
1985 Verschoor A, Frank J, Boublik M. Investigation of the 50 S ribosomal subunit by electron microscopy and image analysis. Journal of Ultrastructure Research. 92: 180-189. PMID 3913778 DOI: 10.1016/0889-1605(85)90045-X  0.319
1985 Kim CH, Radermacher M, Kessel M, Frank J, King TE. Three-dimensional reconstruction of cytochrome oxidase vesicle crystals prepared by cholate solubilization. Journal of Inorganic Biochemistry. 23: 163-9. PMID 2991453 DOI: 10.1016/0162-0134(85)85021-2  0.304
1984 Mannella CA, Frank J. Electron Microscopic Stains as Probes of the Surface Charge of Mitochondrial Outer Membrane Channels Biophysical Journal. 45: 139-141. PMID 19431542 DOI: 10.1016/S0006-3495(84)84140-5  0.598
1984 Woodcock CLF, Frank J. Nucleosome mass distribution using image averaging Journal of Ultrastructure Research. 89: 295-302. PMID 6544891 DOI: 10.1016/S0022-5320(84)80045-3  0.307
1984 Radermacher M, Frank J. Representation of three-dimensionally reconstructed objects in electron microscopy by surfaces of equal density. Journal of Microscopy. 136: 77-85. PMID 6392559 DOI: 10.1111/J.1365-2818.1984.Tb02547.X  0.33
1984 Verschoor A, Frank J, Radermacher M, Wagenknecht T, Boublik M. Three-dimensional reconstruction of the 30 S ribosomal subunit from randomly oriented particles Journal of Molecular Biology. 178: 677-695. PMID 6387155 DOI: 10.1016/0022-2836(84)90245-6  0.318
1984 Wagenknecht T, Frank J. Localization of lipoyl-bearing domains in the α-ketoglutarate dehydrogenase multienzyme complex Biochemistry. 23: 3383-3389. PMID 6380587 DOI: 10.1021/Bi00310A001  0.359
1984 Mannella CA, Frank J. Negative staining characteristics of arrays of mitochondrial pore protein: use of correspondence analysis to classify different staining patterns. Ultramicroscopy. 13: 93-102. PMID 6206632 DOI: 10.1016/0304-3991(84)90060-3  0.578
1984 Frank J. The role of multivariate image analysis in solving the architecture of the limulus polyphemus hemocyanin molecule Ultramicroscopy. 13: 153-164. DOI: 10.1016/0304-3991(84)90065-2  0.324
1983 Frank J, van Heel M. Correspondence analysis of aligned images of biological particles. Journal of Molecular Biology. 161: 134-7. PMID 7154073 DOI: 10.1016/0022-2836(82)90282-0  0.578
1983 Mannella CA, Colombini M, Frank J. Structural and functional evidence for multiple channel complexes in the outer membrane of Neurospora crassa mitochondria. Proceedings of the National Academy of Sciences of the United States of America. 80: 2243-7. PMID 6300902 DOI: 10.1073/Pnas.80.8.2243  0.569
1982 Mannella CA, Frank J. Effects of divalent metal ions and chelators on the structure of outer mitochondrial membranes from neurospora crassa. Biophysical Journal. 37: 3-4. PMID 19431484 DOI: 10.1016/S0006-3495(82)84569-4  0.543
1982 Lamy J, Sizaret PY, Frank J, Verschoor A, Feldmann R, Bonaventura J. Architecture of Limulus polyphemus hemocyanin. Biochemistry. 21: 6825-33. PMID 7159564 DOI: 10.1021/Bi00269A031  0.316
1982 Zingsheim HP, Barrantes FJ, Frank J, Hänicke W, Neugebauer DC. Direct structural localization of two toxin-recognition sites on an ACh receptor protein Nature. 299: 81-84. PMID 7110329 DOI: 10.1038/299081A0  0.32
1982 Frank J, Verschoor A, Boublik M. Multivariate statistical analysis of ribosome electron micrographs. L and R lateral views of the 40 S subunit from HeLa cells. Journal of Molecular Biology. 161: 107-133. PMID 6185684 DOI: 10.1016/0022-2836(82)90281-9  0.312
1982 Zingsheim HP, Neugebauer DC, Frank J, Hänicke W, Barrantes FJ. Dimeric arrangement and structure of the membrane-bound acetylcholine receptor studied by electron microscopy. The Embo Journal. 1: 541-547. DOI: 10.1002/J.1460-2075.1982.Tb01206.X  0.357
1981 Frank J, Verschoor A, Boublik M. Computer Averaging of Electron Micrographs of 40S Ribosomal Subunits Science. 214: 1353-1355. PMID 7313694 DOI: 10.1126/Science.7313694  0.371
1981 Frank J. Three-dimensional reconstruction of single molecules Methods in Cell Biology. 22: 325-344. PMID 7022121 DOI: 10.1016/S0091-679X(08)61882-8  0.304
1981 Frank J, Shimkin B, Dowse H. SPIDER—A modular software system for electron image processing Ultramicroscopy. 6: 343-357. DOI: 10.1016/S0304-3991(81)80221-5  0.318
1981 Frank J. chapter 12 Introduction Methods in Cell Biology. 22: 199-213. DOI: 10.1016/S0091-679X(08)61878-6  0.308
1980 Zingsheim HP, Neugebauer -Ch. D, Barrantes FJ, Frank J. Structural details of membrane-bound acetylcholine receptor from Torpedo marmorata Proceedings of the National Academy of Sciences of the United States of America. 77: 952-956. PMID 6928692 DOI: 10.1073/Pnas.77.2.952  0.329
1979 Frank J. Image Analysis In Electron Microscopy Journal of Microscopy. 117: 25-38. DOI: 10.1111/J.1365-2818.1979.Tb00229.X  0.324
1975 Frank J. Controlled focusing and stigmating in the conventional and scanning transmission electron microscope Journal of Physics E: Scientific Instruments. 8: 582-587. DOI: 10.1088/0022-3735/8/7/014  0.324
1969 Hoppe W, Langer R, Frank J, Feltynowski A. [Image differentiation procedures in electron microscopy]. Die Naturwissenschaften. 56: 267-72. PMID 5360874 DOI: 10.1007/Bf00633921  0.549
1969 Langer R, Formanek S, Frank J, Martin HH, Hoppe W. [Structure of the murein sacculus of Spirillum serpens. Quantitative electron microscopy studies at high resolution]. Hoppe-Seyler's Zeitschrift FüR Physiologische Chemie. 350: 1173-4. PMID 5352337  0.543
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