| Year |
Citation |
Score |
| 2023 |
Mullowney MW, Duncan KR, Elsayed SS, Garg N, van der Hooft JJJ, Martin NI, Meijer D, Terlouw BR, Biermann F, Blin K, Durairaj J, Gorostiola González M, Helfrich EJN, Huber F, Leopold-Messer S, ... ... Linington RG, et al. Artificial intelligence for natural product drug discovery. Nature Reviews. Drug Discovery. PMID 37697042 DOI: 10.1038/s41573-023-00774-7 |
0.438 |
|
| 2023 |
Vidar WS, Baumeister TUH, Caesar LK, Kellogg JJ, Todd DA, Linington RG, M Kvalheim O, Cech NB. Interaction Metabolomics to Discover Synergists in Natural Product Mixtures. Journal of Natural Products. PMID 37052585 DOI: 10.1021/acs.jnatprod.2c00518 |
0.603 |
|
| 2023 |
Khadilkar A, Bunch ZL, Wagoner J, Ravindran V, Oda JM, Vidar WS, Clark TN, Manwill PK, Todd DA, Barr SA, Olinger LK, Fink SL, Strangman WK, Linington RG, MacMillan JB, et al. Modulation of SARS-CoV-2 Infection by and Its Alkaloid Constituents. Journal of Natural Products. PMID 37043739 DOI: 10.1021/acs.jnatprod.3c00159 |
0.585 |
|
| 2022 |
Takaki M, Williams DE, Freire VF, Sartori SB, Lira SP, Bizarria R, Rodrigues A, Gonçalves da Costa DR, Amorim MR, Ferreira AG, Andersen RJ, Linington RG, Berlinck RGS. Metabolomics Reveals a 26-Membered Macrolactone Produced by Endophytic spp. from Alcatrazes Island, Brazil. Organic Letters. PMID 36521009 DOI: 10.1021/acs.orglett.2c03531 |
0.436 |
|
| 2022 |
Hight SK, Clark TN, Kurita KL, McMillan EA, Bray W, Shaikh AF, Khadilkar A, Haeckl FPJ, Carnevale-Neto F, La S, Lohith A, Vaden RM, Lee J, Wei S, Lokey RS, ... ... Linington RG, et al. High-throughput functional annotation of natural products by integrated activity profiling. Proceedings of the National Academy of Sciences of the United States of America. 119: e2208458119. PMID 36449542 DOI: 10.1073/pnas.2208458119 |
0.751 |
|
| 2022 |
Linington RG, Keller L, Choi H, Bertin MJ. Special Issue in Honor of Professor William Gerwick. Journal of Natural Products. 85: 459-461. PMID 35330994 DOI: 10.1021/acs.jnatprod.2c00100 |
0.589 |
|
| 2022 |
Flores-Bocanegra L, Al Subeh ZY, Egan JM, El-Elimat T, Raja HA, Burdette JE, Pearce CJ, Linington RG, Oberlies NH. Dereplication of Fungal Metabolites by NMR-Based Compound Networking Using MADByTE. Journal of Natural Products. PMID 35020372 DOI: 10.1021/acs.jnatprod.1c00841 |
0.805 |
|
| 2021 |
McCaughey CS, van Santen JA, van der Hooft JJJ, Medema MH, Linington RG. An isotopic labeling approach linking natural products with biosynthetic gene clusters. Nature Chemical Biology. PMID 34969972 DOI: 10.1038/s41589-021-00949-6 |
0.796 |
|
| 2021 |
Tran W, Kusay AS, Hawkins PME, Cheung CY, Nagalingam G, Pujari V, Ford DJ, Stoye A, Ochoa JL, Audette RE, Hortle E, Oehlers SH, Charman SA, Linington RG, Rubin EJ, et al. Synthetic Sansanmycin Analogues as Potent Translocase I Inhibitors. Journal of Medicinal Chemistry. 64: 17326-17345. PMID 34845906 DOI: 10.1021/acs.jmedchem.1c01407 |
0.763 |
|
| 2021 |
van Santen JA, Poynton EF, Iskakova D, McMann E, Alsup TA, Clark TN, Fergusson CH, Fewer DP, Hughes AH, McCadden CA, Parra J, Soldatou S, Rudolf JD, Janssen EM, Duncan KR, ... Linington RG, et al. The Natural Products Atlas 2.0: a database of microbially-derived natural products. Nucleic Acids Research. PMID 34718710 DOI: 10.1093/nar/gkab941 |
0.325 |
|
| 2021 |
Challa VR, Kwon D, Taron M, Fan H, Kang B, Wilson D, Haeckl FPJ, Keerthisinghe S, Linington RG, Britton R. Total synthesis of biselide A. Chemical Science. 12: 5534-5543. PMID 34168790 DOI: 10.1039/d0sc06223e |
0.511 |
|
| 2021 |
Egan JM, van Santen JA, Liu DY, Linington RG. Development of an NMR-Based Platform for the Direct Structural Annotation of Complex Natural Products Mixtures. Journal of Natural Products. PMID 33750122 DOI: 10.1021/acs.jnatprod.0c01076 |
0.792 |
|
| 2021 |
Clark TN, Houriet J, Vidar WS, Kellogg JJ, Todd DA, Cech NB, Linington RG. Interlaboratory Comparison of Untargeted Mass Spectrometry Data Uncovers Underlying Causes for Variability. Journal of Natural Products. PMID 33666420 DOI: 10.1021/acs.jnatprod.0c01376 |
0.547 |
|
| 2020 |
Claesen J, Spagnolo JB, Ramos SF, Kurita KL, Byrd AL, Aksenov AA, Melnik AV, Wong WR, Wang S, Hernandez RD, Donia MS, Dorrestein PC, Kong HH, Segre JA, Linington RG, et al. A antibiotic modulates human skin microbiota composition in hair follicles. Science Translational Medicine. 12. PMID 33208503 DOI: 10.1126/scitranslmed.aay5445 |
0.723 |
|
| 2020 |
van Santen JA, Kautsar SA, Medema MH, Linington RG. Microbial natural product databases: moving forward in the multi-omics era. Natural Product Reports. PMID 32856641 DOI: 10.1039/D0Np00053A |
0.374 |
|
| 2020 |
Fergusson CH, Coloma JMF, Valentine MC, Haeckl FPJ, Linington RG. Development of a Custom MALDI-TOF Mass Spectrometric Database for Identification of Environmental and Related Genera. Applied and Environmental Microbiology. PMID 32245762 DOI: 10.1128/Aem.00354-20 |
0.439 |
|
| 2020 |
Kelly P, Hadi-Nezhad F, Liu DY, Lawrence TJ, Linington RG, Ibba M, Ardell DH. Targeting tRNA-synthetase interactions towards novel therapeutic discovery against eukaryotic pathogens. Plos Neglected Tropical Diseases. 14: e0007983. PMID 32106219 DOI: 10.1371/Journal.Pntd.0007983 |
0.351 |
|
| 2020 |
Yoo E, Schulze CJ, Stokes BH, Onguka O, Yeo T, Mok S, Gnädig NF, Zhou Y, Kurita K, Foe IT, Terrell SM, Boucher MJ, Cieplak P, Kumpornsin K, Lee MCS, ... Linington RG, et al. The Antimalarial Natural Product Salinipostin A Identifies Essential α/β Serine Hydrolases Involved in Lipid Metabolism in P. falciparum Parasites. Cell Chemical Biology. PMID 31978322 DOI: 10.1016/J.Chembiol.2020.01.001 |
0.782 |
|
| 2019 |
van Santen JA, Jacob G, Singh AL, Aniebok V, Balunas MJ, Bunsko D, Neto FC, Castaño-Espriu L, Chang C, Clark TN, Cleary Little JL, Delgadillo DA, Dorrestein PC, Duncan KR, Egan JM, ... ... Linington RG, et al. The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery. Acs Central Science. 5: 1824-1833. PMID 31807684 DOI: 10.1021/Acscentsci.9B00806 |
0.773 |
|
| 2019 |
Kautsar SA, Blin K, Shaw S, Navarro-Muñoz JC, Terlouw BR, van der Hooft JJJ, van Santen JA, Tracanna V, Suarez Duran HG, Pascal Andreu V, Selem-Mojica N, Alanjary M, Robinson SL, Lund G, Epstein SC, ... ... Linington RG, et al. MIBiG 2.0: a repository for biosynthetic gene clusters of known function. Nucleic Acids Research. PMID 31612915 DOI: 10.1093/Nar/Gkz882 |
0.31 |
|
| 2019 |
Linington RG, Kubanek J, Luesch H. New methods for isolation and structure determination of natural products. Natural Product Reports. PMID 31250867 DOI: 10.1039/C9Np90023C |
0.382 |
|
| 2019 |
Ren W, Gries R, Kurita KL, McCaughey CS, Alamsetti SK, Linington RG, Gries G, Britton R. Isolation, Structure Elucidation, and Total Synthesis of Dolichovespulide, a Sesquiterpene from Dolichovespula Yellowjackets. Journal of Natural Products. PMID 31244148 DOI: 10.1021/Acs.Jnatprod.9B00238 |
0.779 |
|
| 2019 |
Haeckl FPJ, Baldim JL, Iskakova D, Kurita KL, Soares MG, Linington RG. A selective genome-guided method for environmental Burkholderia isolation. Journal of Industrial Microbiology & Biotechnology. PMID 30680473 DOI: 10.1007/S10295-018-02121-X |
0.747 |
|
| 2018 |
Warner CJA, Salinas M, Zamorano-Sánchez D, Bray WM, Lokey RS, Yildiz FH, Linington RG. The Bioactive Lipid (S)-Sebastenoic Acid Impacts Motility and Dispersion in . Canadian Journal of Chemistry. 96: 196-203. PMID 34158674 DOI: 10.1139/cjc-2017-0334 |
0.311 |
|
| 2018 |
McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, ... ... Linington RG, et al. Correction: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research. Natural Product Reports. PMID 30468235 DOI: 10.1039/c8np90041h |
0.782 |
|
| 2018 |
Ueoka R, Bhushan A, Probst SI, Bray WM, Lokey RS, Linington RG, Piel J. Genome-based identification of a plant-associated marine bacterium as a rich natural product source. Angewandte Chemie (International Ed. in English). PMID 30025185 DOI: 10.1002/Anie.201805673 |
0.412 |
|
| 2018 |
McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, ... ... Linington RG, et al. The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research. Natural Product Reports. PMID 30003207 DOI: 10.1039/C7Np00064B |
0.788 |
|
| 2018 |
Corcilius L, Liu DY, Ochoa JL, Linington RG, Payne RJ. Synthesis and evaluation of analogues of the glycinocin family of calcium-dependent antibiotics. Organic & Biomolecular Chemistry. PMID 29993080 DOI: 10.1039/C8Ob01268G |
0.76 |
|
| 2018 |
Ren W, Gries R, McCaughey C, Derstine N, Alamsetti S, Kurita K, Tu L, Linington R, Britton R, Gries GJ. Maculatic acids - sex attractant pheromone components of bald-faced hornets. Angewandte Chemie (International Ed. in English). PMID 29890016 DOI: 10.1002/Anie.201804666 |
0.761 |
|
| 2018 |
Giltrap AM, Haeckl FPJ, Kurita KL, Linington RG, Payne RJ. Synthetic Studies Towards the Skyllamycins: Total Synthesis and Generation of Simplified Analogues. The Journal of Organic Chemistry. PMID 29798664 DOI: 10.1021/Acs.Joc.8B00898 |
0.753 |
|
| 2018 |
Warner CJ, Salinas M, Zamorano-Sánchez D, Bray WM, Lokey RS, Yildiz FH, Linington RG. The bioactive lipid (S)-sebastenoic acid impacts motility and dispersion in Vibrio cholerae Canadian Journal of Chemistry. 96: 196-203. DOI: 10.1139/Cjc-2017-0334 |
0.424 |
|
| 2018 |
Ueoka R, Bhushan A, Probst SI, Bray WM, Lokey RS, Linington RG, Piel J. Inside Cover: Genome-Based Identification of a Plant-Associated Marine Bacterium as a Rich Natural Product Source (Angew. Chem. Int. Ed. 44/2018) Angewandte Chemie International Edition. 57: 14294-14294. DOI: 10.1002/Anie.201811589 |
0.318 |
|
| 2018 |
Ren W, Gries R, McCaughey C, Derstine N, Alamsetti SK, Kurita KL, Tu L, Linington RG, Britton R, Gries G. Cover Picture: Maculatic Acids—Sex Attractant Pheromone Components of Bald‐Faced Hornets (Angew. Chem. Int. Ed. 36/2018) Angewandte Chemie International Edition. 57: 11473-11473. DOI: 10.1002/Anie.201808278 |
0.695 |
|
| 2018 |
Ueoka R, Bhushan A, Probst SI, Bray WM, Lokey RS, Linington RG, Piel J. Innentitelbild: Genome-Based Identification of a Plant-Associated Marine Bacterium as a Rich Natural Product Source (Angew. Chem. 44/2018) Angewandte Chemie. 130: 14490-14490. DOI: 10.1002/Ange.201811589 |
0.319 |
|
| 2018 |
Ren W, Gries R, McCaughey C, Derstine N, Alamsetti SK, Kurita KL, Tu L, Linington RG, Britton R, Gries G. Titelbild: Maculatic Acids-Sex Attractant Pheromone Components of Bald-Faced Hornets (Angew. Chem. 36/2018) Angewandte Chemie. 130: 11645-11645. DOI: 10.1002/Ange.201808278 |
0.698 |
|
| 2017 |
Ochoa JL, Sanchez LM, Koo BM, Doherty JS, Rajendram M, Huang KC, Gross CA, Linington RG. Marine Mammal Microbiota Yields Novel Antibiotic with Potent Activity Against Clostridium difficile. Acs Infectious Diseases. PMID 29043783 DOI: 10.1021/Acsinfecdis.7B00105 |
0.803 |
|
| 2017 |
Corcilius L, Elias NT, Ochoa JL, Linington RG, Payne RJ. Total Synthesis of Glycinocins A-C. The Journal of Organic Chemistry. PMID 28914054 DOI: 10.1021/Acs.Joc.7B01959 |
0.763 |
|
| 2017 |
Payne RJ, Giltrap A, Haeckl J, Kurita K, Linington R. Total Synthesis of Skyllamycins A-C. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28906041 DOI: 10.1002/Chem.201704277 |
0.753 |
|
| 2017 |
Pye CR, Bertin MJ, Lokey RS, Gerwick WH, Linington RG. Reply to Skinnider and Magarvey: Rates of novel natural product discovery remain high. Proceedings of the National Academy of Sciences of the United States of America. PMID 28710331 DOI: 10.1073/Pnas.1711139114 |
0.744 |
|
| 2017 |
Pye CR, Bertin MJ, Lokey RS, Gerwick WH, Linington RG. Retrospective analysis of natural products provides insights for future discovery trends. Proceedings of the National Academy of Sciences of the United States of America. PMID 28461474 DOI: 10.1073/Pnas.1614680114 |
0.777 |
|
| 2017 |
Tran AT, Watson EE, Pujari V, Conroy T, Dowman LJ, Giltrap AM, Pang A, Wong WR, Linington RG, Mahapatra S, Saunders J, Charman SA, West NP, Bugg TD, Tod J, et al. Sansanmycin natural product analogues as potent and selective anti-mycobacterials that inhibit lipid I biosynthesis. Nature Communications. 8: 14414. PMID 28248311 DOI: 10.1038/Ncomms14414 |
0.336 |
|
| 2016 |
Harms H, Kurita KL, Pan L, Wahome PG, He H, Kinghorn AD, Carter GT, Linington RG. Discovery of anabaenopeptin 679 from freshwater algal bloom material: Insights into the structure-activity relationship of anabaenopeptin protease inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 27641470 DOI: 10.1016/J.Bmcl.2016.09.008 |
0.77 |
|
| 2016 |
Wang M, Carver JJ, Phelan VV, Sanchez LM, Garg N, Peng Y, Nguyen DD, Watrous J, Kapono CA, Luzzatto-Knaan T, Porto C, Bouslimani A, Melnik AV, Meehan MJ, Liu WT, ... ... Linington RG, et al. Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking. Nature Biotechnology. 34: 828-837. PMID 27504778 DOI: 10.1038/Nbt.3597 |
0.769 |
|
| 2016 |
Giltrap AM, Dowman LJ, Nagalingam G, Ochoa JL, Linington RG, Britton WJ, Payne RJ. Total Synthesis of Teixobactin. Organic Letters. PMID 27191730 DOI: 10.1021/Acs.Orglett.6B01324 |
0.771 |
|
| 2016 |
Sanchez LM, Cheng AT, Warner CJ, Townsley L, Peach KC, Navarro G, Shikuma NJ, Bray WM, Riener RM, Yildiz FH, Linington RG. Biofilm Formation and Detachment in Gram-Negative Pathogens Is Modulated by Select Bile Acids. Plos One. 11: e0149603. PMID 26992172 DOI: 10.1371/Journal.Pone.0149603 |
0.802 |
|
| 2015 |
Effenberger KA, James RC, Urabe VK, Dickey BJ, Linington RG, Jurica MS. The Natural Product N-palmitoyl-L-leucine Selectively Inhibits Late Assembly of Human Spliceosomes. The Journal of Biological Chemistry. PMID 26408199 DOI: 10.1074/Jbc.M115.673210 |
0.383 |
|
| 2015 |
Kurita KL, Glassey E, Linington RG. Integration of high-content screening and untargeted metabolomics for comprehensive functional annotation of natural product libraries. Proceedings of the National Academy of Sciences of the United States of America. 112: 11999-2004. PMID 26371303 DOI: 10.1073/Pnas.1507743112 |
0.815 |
|
| 2015 |
Ochoa JL, Bray WM, Lokey RS, Linington RG. Phenotype-Guided Natural Products Discovery Using Cytological Profiling. Journal of Natural Products. 78: 2242-8. PMID 26292657 DOI: 10.1021/Acs.Jnatprod.5B00455 |
0.785 |
|
| 2015 |
Schulze CJ, Donia MS, Siqueira-Neto JL, Ray D, Raskatov JA, Green RE, McKerrow JH, Fischbach MA, Linington RG. Genome-Directed Lead Discovery: Biosynthesis, Structure Elucidation, and Biological Evaluation of Two Families of Polyene Macrolactams against Trypanosoma brucei. Acs Chemical Biology. PMID 26270237 DOI: 10.1021/Acschembio.5B00308 |
0.764 |
|
| 2015 |
Shao CL, Linington RG, Balunas MJ, Centeno A, Boudreau P, Zhang C, Engene N, Spadafora C, Mutka TS, Kyle DE, Gerwick L, Wang CY, Gerwick WH. Bastimolide A, a Potent Antimalarial Polyhydroxy Macrolide from the Marine Cyanobacterium Okeania hirsuta. The Journal of Organic Chemistry. PMID 26222145 DOI: 10.1021/Acs.Joc.5B01264 |
0.749 |
|
| 2015 |
León B, Haeckl FP, Linington RG. Optimized quinoline amino alcohols as disruptors and dispersal agents of Vibrio cholerae biofilms. Organic & Biomolecular Chemistry. PMID 26156292 DOI: 10.1039/C5Ob01134E |
0.79 |
|
| 2015 |
Teschler JK, Zamorano-Sánchez D, Utada AS, Warner CJ, Wong GC, Linington RG, Yildiz FH. Living in the matrix: assembly and control of Vibrio cholerae biofilms. Nature Reviews. Microbiology. 13: 255-68. PMID 25895940 DOI: 10.1038/Nrmicro3433 |
0.302 |
|
| 2015 |
Kurita KL, Linington RG. Connecting phenotype and chemotype: high-content discovery strategies for natural products research. Journal of Natural Products. 78: 587-96. PMID 25728167 DOI: 10.1021/Acs.Jnatprod.5B00017 |
0.771 |
|
| 2015 |
Schulze CJ, Navarro G, Ebert D, DeRisi J, Linington RG. Salinipostins A-K, long-chain bicyclic phosphotriesters as a potent and selective antimalarial chemotype. The Journal of Organic Chemistry. 80: 1312-20. PMID 25584395 DOI: 10.1021/Jo5024409 |
0.804 |
|
| 2015 |
León B, Navarro G, Dickey BJ, Stepan G, Tsai A, Jones GS, Morales ME, Barnes T, Ahmadyar S, Tsiang M, Geleziunas R, Cihlar T, Pagratis N, Tian Y, Yu H, ... Linington RG, et al. Abyssomicin 2 reactivates latent HIV-1 by a PKC- and HDAC-independent mechanism. Organic Letters. 17: 262-5. PMID 25560385 DOI: 10.1021/Ol503349Y |
0.765 |
|
| 2015 |
Warner CJ, Cheng AT, Yildiz FH, Linington RG. Development of benzo[1,4]oxazines as biofilm inhibitors and dispersal agents against Vibrio cholerae. Chemical Communications (Cambridge, England). 51: 1305-8. PMID 25479128 DOI: 10.1039/C4Cc07003H |
0.321 |
|
| 2015 |
Haeckl F, Blöhbaum J, León B, Jones C, Cheng A, Bray W, Yildiz F, Linington R. Biocompatible polymer delivery of biofilm disruptors of Vibrio cholerae Planta Medica. 81. DOI: 10.1055/S-0035-1556225 |
0.754 |
|
| 2015 |
Ochoa J, Sanchez L, Linington R. Phylogenetic and metabolomic analysis of marine mammal microbes contributes to emerging spirotetronate polyketides Planta Medica. 81. DOI: 10.1055/S-0035-1556166 |
0.749 |
|
| 2015 |
Pye C, Bertin M, Lokey R, Gerwick W, Linington R. Natural products: Are we close to the end? Planta Medica. 81. DOI: 10.1055/S-0035-1556160 |
0.737 |
|
| 2014 |
Schulze CJ, Bray WM, Loganzo F, Lam MH, Szal T, Villalobos A, Koehn FE, Linington RG. Borrelidin B: isolation, biological activity, and implications for nitrile biosynthesis. Journal of Natural Products. 77: 2570-4. PMID 25393949 DOI: 10.1021/Np500727G |
0.749 |
|
| 2014 |
Donia MS, Cimermancic P, Schulze CJ, Wieland Brown LC, Martin J, Mitreva M, Clardy J, Linington RG, Fischbach MA. A systematic analysis of biosynthetic gene clusters in the human microbiome reveals a common family of antibiotics. Cell. 158: 1402-14. PMID 25215495 DOI: 10.1016/J.Cell.2014.08.032 |
0.726 |
|
| 2014 |
Cimermancic P, Medema MH, Claesen J, Kurita K, Wieland Brown LC, Mavrommatis K, Pati A, Godfrey PA, Koehrsen M, Clardy J, Birren BW, Takano E, Sali A, Linington RG, Fischbach MA. Insights into secondary metabolism from a global analysis of prokaryotic biosynthetic gene clusters. Cell. 158: 412-21. PMID 25036635 DOI: 10.1016/J.Cell.2014.06.034 |
0.733 |
|
| 2014 |
Higginbotham S, Wong WR, Linington RG, Spadafora C, Iturrado L, Arnold AE. Sloth hair as a novel source of fungi with potent anti-parasitic, anti-cancer and anti-bacterial bioactivity. Plos One. 9: e84549. PMID 24454729 DOI: 10.1371/Journal.Pone.0084549 |
0.395 |
|
| 2014 |
Duncan MC, Wong WR, Dupzyk AJ, Bray WM, Linington RG, Auerbuch V. An NF-κB-based high-throughput screen identifies piericidins as inhibitors of the Yersinia pseudotuberculosis type III secretion system. Antimicrobial Agents and Chemotherapy. 58: 1118-26. PMID 24295981 DOI: 10.1128/Aac.02025-13 |
0.316 |
|
| 2014 |
Navarro G, Cheng AT, Peach KC, Bray WM, Bernan VS, Yildiz FH, Linington RG. Image-based 384-well high-throughput screening method for the discovery of skyllamycins A to C as biofilm inhibitors and inducers of biofilm detachment in Pseudomonas aeruginosa. Antimicrobial Agents and Chemotherapy. 58: 1092-9. PMID 24295976 DOI: 10.1128/Aac.01781-13 |
0.797 |
|
| 2014 |
Liu WT, Lamsa A, Wong WR, Boudreau PD, Kersten R, Peng Y, Moree WJ, Duggan BM, Moore BS, Gerwick WH, Linington RG, Pogliano K, Dorrestein PC. MS/MS-based networking and peptidogenomics guided genome mining revealed the stenothricin gene cluster in Streptomyces roseosporus. The Journal of Antibiotics. 67: 99-104. PMID 24149839 DOI: 10.1038/Ja.2013.99 |
0.646 |
|
| 2013 |
Peach KC, Cheng AT, Oliver AG, Yildiz FH, Linington RG. Discovery and biological characterization of the auromomycin chromophore as an inhibitor of biofilm formation in Vibrio cholerae. Chembiochem : a European Journal of Chemical Biology. 14: 2209-15. PMID 24106077 DOI: 10.1002/Cbic.201300131 |
0.813 |
|
| 2013 |
Yang JY, Sanchez LM, Rath CM, Liu X, Boudreau PD, Bruns N, Glukhov E, Wodtke A, de Felicio R, Fenner A, Wong WR, Linington RG, Zhang L, Debonsi HM, Gerwick WH, et al. Molecular networking as a dereplication strategy. Journal of Natural Products. 76: 1686-99. PMID 24025162 DOI: 10.1021/Np400413S |
0.78 |
|
| 2013 |
Peach KC, Bray WM, Winslow D, Linington PF, Linington RG. Mechanism of action-based classification of antibiotics using high-content bacterial image analysis. Molecular Biosystems. 9: 1837-48. PMID 23609915 DOI: 10.1039/C3Mb70027E |
0.798 |
|
| 2013 |
León B, Fong JC, Peach KC, Wong WR, Yildiz FH, Linington RG. Development of quinoline-based disruptors of biofilm formation against Vibrio cholerae. Organic Letters. 15: 1234-7. PMID 23461487 DOI: 10.1021/Ol400150Z |
0.78 |
|
| 2013 |
Sanchez LM, Knudsen GM, Helbig C, De Muylder G, Mascuch SM, Mackey ZB, Gerwick L, Clayton C, McKerrow JH, Linington RG. Examination of the mode of action of the almiramide family of natural products against the kinetoplastid parasite Trypanosoma brucei. Journal of Natural Products. 76: 630-41. PMID 23445522 DOI: 10.1021/Np300834Q |
0.725 |
|
| 2013 |
Schulze CJ, Bray WM, Woerhmann MH, Stuart J, Lokey RS, Linington RG. "Function-first" lead discovery: mode of action profiling of natural product libraries using image-based screening. Chemistry & Biology. 20: 285-95. PMID 23438757 DOI: 10.1016/J.Chembiol.2012.12.007 |
0.754 |
|
| 2012 |
Wong WR, Oliver AG, Linington RG. Development of antibiotic activity profile screening for the classification and discovery of natural product antibiotics. Chemistry & Biology. 19: 1483-95. PMID 23177202 DOI: 10.1016/J.Chembiol.2012.09.014 |
0.439 |
|
| 2012 |
Carlile GW, Keyzers RA, Teske KA, Robert R, Williams DE, Linington RG, Gray CA, Centko RM, Yan L, Anjos SM, Sampson HM, Zhang D, Liao J, Hanrahan JW, Andersen RJ, et al. Correction of F508del-CFTR trafficking by the sponge alkaloid latonduine is modulated by interaction with PARP. Chemistry & Biology. 19: 1288-99. PMID 23102222 DOI: 10.1016/J.Chembiol.2012.08.014 |
0.477 |
|
| 2012 |
Navarro G, Chokpaiboon S, De Muylder G, Bray WM, Nisam SC, McKerrow JH, Pudhom K, Linington RG. Hit-to-lead development of the chamigrane endoperoxide merulin A for the treatment of African sleeping sickness. Plos One. 7: e46172. PMID 23029428 DOI: 10.1371/Journal.Pone.0046172 |
0.624 |
|
| 2012 |
Duncan MC, Linington RG, Auerbuch V. Chemical inhibitors of the type three secretion system: disarming bacterial pathogens. Antimicrobial Agents and Chemotherapy. 56: 5433-41. PMID 22850518 DOI: 10.1128/Aac.00975-12 |
0.341 |
|
| 2012 |
Sanchez LM, Wong WR, Riener RM, Schulze CJ, Linington RG. Examining the fish microbiome: vertebrate-derived bacteria as an environmental niche for the discovery of unique marine natural products. Plos One. 7: e35398. PMID 22574119 DOI: 10.1371/Journal.Pone.0035398 |
0.811 |
|
| 2012 |
Navarro G, Peach K, Cheng A, Bray W, Yildiz F, Linington R. An image-based 384-well high-throughput screening method for phenotypic discovery of biofilm inhibitors in Pseudomonas aeruginosa Planta Medica. 78. DOI: 10.1055/S-0032-1320503 |
0.657 |
|
| 2012 |
Ruh Wong W, Oliver A, Linington R. Antibiotic mode of action profiling (Biomap) as a platform for the discovery of novel natural product antibiotics Planta Medica. 78. DOI: 10.1055/S-0032-1320307 |
0.361 |
|
| 2011 |
Conroy T, Guo JT, Linington RG, Hunt NH, Payne RJ. Total synthesis, stereochemical assignment, and antimalarial activity of gallinamide A. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 13544-52. PMID 22006835 DOI: 10.1002/Chem.201102538 |
0.385 |
|
| 2011 |
Radjasa OK, Vaske YM, Navarro G, Vervoort HC, Tenney K, Linington RG, Crews P. Highlights of marine invertebrate-derived biosynthetic products: their biomedical potential and possible production by microbial associants. Bioorganic & Medicinal Chemistry. 19: 6658-74. PMID 21835627 DOI: 10.1016/J.Bmc.2011.07.017 |
0.726 |
|
| 2011 |
Sanchez LM, Curtis ME, Bracamonte BE, Kurita KL, Navarro G, Sparkman OD, Linington RG. Versatile method for the detection of covalently bound substrates on solid supports by DART mass spectrometry. Organic Letters. 13: 3770-3. PMID 21699263 DOI: 10.1021/Ol201404V |
0.766 |
|
| 2011 |
Nunnery JK, Suyama TL, Linington RG, Gerwick WH. Expedient synthesis of α,α-dimethyl-β-hydroxy carbonyl scaffolds via Evans' aldol reaction with a tertiary enolate. Tetrahedron Letters. 52: 2929-2932. PMID 21617761 DOI: 10.1016/J.Tetlet.2011.03.126 |
0.777 |
|
| 2011 |
Peach KC, Bray WM, Shikuma NJ, Gassner NC, Lokey RS, Yildiz FH, Linington RG. An image-based 384-well high-throughput screening method for the discovery of biofilm inhibitors in Vibrio cholerae. Molecular Biosystems. 7: 1176-84. PMID 21246108 DOI: 10.1039/C0Mb00276C |
0.788 |
|
| 2010 |
Sanchez LM, Lopez D, Vesely BA, Della Togna G, Gerwick WH, Kyle DE, Linington RG. Almiramides A-C: discovery and development of a new class of leishmaniasis lead compounds. Journal of Medicinal Chemistry. 53: 4187-97. PMID 20441198 DOI: 10.1021/Jm100265S |
0.781 |
|
| 2010 |
Balunas MJ, Linington RG, Tidgewell K, Fenner AM, Ureña LD, Togna GD, Kyle DE, Gerwick WH. Dragonamide E, a modified linear lipopeptide from Lyngbya majuscula with antileishmanial activity. Journal of Natural Products. 73: 60-6. PMID 20030365 DOI: 10.1021/Np900622M |
0.783 |
|
| 2009 |
Peach KC, Linington RG. New innovations for an old infection: antimalarial lead discovery from marine natural products during the period 2003-2008. Future Medicinal Chemistry. 1: 593-617. PMID 21426029 DOI: 10.4155/Fmc.09.56 |
0.803 |
|
| 2009 |
Ng J, Bandeira N, Liu WT, Ghassemian M, Simmons TL, Gerwick WH, Linington R, Dorrestein PC, Pevzner PA. Dereplication and de novo sequencing of nonribosomal peptides. Nature Methods. 6: 596-9. PMID 19597502 DOI: 10.1038/Nmeth.1350 |
0.771 |
|
| 2009 |
Liu WT, Ng J, Meluzzi D, Bandeira N, Gutierrez M, Simmons TL, Schultz AW, Linington RG, Moore BS, Gerwick WH, Pevzner PA, Dorrestein PC. Interpretation of tandem mass spectra obtained from cyclic nonribosomal peptides. Analytical Chemistry. 81: 4200-9. PMID 19413302 DOI: 10.1021/Ac900114T |
0.783 |
|
| 2009 |
Linington RG, Clark BR, Trimble EE, Almanza A, Ureña LD, Kyle DE, Gerwick WH. Antimalarial peptides from marine cyanobacteria: isolation and structural elucidation of gallinamide A. Journal of Natural Products. 72: 14-7. PMID 19161344 DOI: 10.1021/Np8003529 |
0.547 |
|
| 2008 |
Linington RG, Edwards DJ, Shuman CF, McPhail KL, Matainaho T, Gerwick WH. Symplocamide A, a potent cytotoxin and chymotrypsin inhibitor from the marine Cyanobacterium Symploca sp. Journal of Natural Products. 71: 22-7. PMID 18163584 DOI: 10.1021/Np070280X |
0.649 |
|
| 2008 |
Bandeira N, Ng J, Meluzzi D, Linington RG, Dorrestein P, Pevzner PA. De novo sequencing of nonribosomal peptides Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 4955: 181-195. DOI: 10.1007/978-3-540-78839-3_16 |
0.362 |
|
| 2007 |
McPhail KL, Correa J, Linington RG, Gonzalez J, Ortega-Barría E, Capson TL, Gerwick WH. Antimalarial linear lipopeptides from a Panamanian strain of the marine cyanobacterium Lyngbya majuscula. Journal of Natural Products. 70: 984-8. PMID 17441769 DOI: 10.1021/Np0700772 |
0.519 |
|
| 2007 |
Linington RG, Gonzalez J, Ureña LD, Romero LI, Ortega-Barría E, Gerwick WH. Venturamides A and B: antimalarial constituents of the panamanian marine Cyanobacterium Oscillatoria sp. Journal of Natural Products. 70: 397-401. PMID 17328572 DOI: 10.1021/Np0605790 |
0.554 |
|
| 2007 |
Kursar TA, Caballero-George CC, Capson TL, Cubilla-Rios L, Gerwick WH, Heller MV, Ibañez A, Linington RG, McPhail KL, Ortega-Barría E, Romero LI, Coley PD. Linking bioprospecting with sustainable development and conservation: The Panama case Biodiversity and Conservation. 16: 2789-2800. DOI: 10.1007/S10531-007-9214-2 |
0.461 |
|
| 2006 |
Linington RG, Robertson M, Gauthier A, Finlay BB, MacMillan JB, Molinski TF, van Soest R, Andersen RJ. Caminosides B-D, antimicrobial glycolipids isolated from the marine sponge Caminus sphaeroconia. Journal of Natural Products. 69: 173-7. PMID 16499312 DOI: 10.1021/Np050192H |
0.518 |
|
| 2006 |
Kursar TA, Caballero-George CC, Capson TL, Cubilla-Rios L, Gerwick WH, Gupta MP, Ibañez A, Linington RG, McPhail KL, Ortega-Barr?a E, Romero LI, Solis PN, Coley PD. Securing economic benefits and promoting conservation through bioprospecting Bioscience. 56: 1005-1012. DOI: 10.1641/0006-3568(2006)56[1005:Sebapc]2.0.Co;2 |
0.467 |
|
| 2004 |
Macmillan JB, Linington RG, Andersen RJ, Molinski TF. Stereochemical assignment in acyclic lipids across long distance by circular dichroism: absolute stereochemistry of the aglycone of caminoside A. Angewandte Chemie (International Ed. in English). 43: 5946-51. PMID 15547902 DOI: 10.1002/Anie.200461158 |
0.441 |
|
| 2003 |
Linington RG, Williams DE, Tahir A, van Soest R, Andersen RJ. Latonduines A and B, new alkaloids isolated from the marine sponge Stylissa carteri: structure elucidation, synthesis, and biogenetic implications. Organic Letters. 5: 2735-8. PMID 12868902 DOI: 10.1021/Ol034950B |
0.532 |
|
| 2002 |
Linington RG, Robertson M, Gauthier A, Finlay BB, van Soest R, Andersen RJ. Caminoside A, an antimicrobial glycolipid isolated from the marine sponge Caminus sphaeroconia. Organic Letters. 4: 4089-92. PMID 12423093 DOI: 10.1021/Ol0268337 |
0.554 |
|
| 2002 |
Barsby T, Linington RG, Andersen RJ. De Novo terpenoid biosynthesis by the dendronotid nudibranch Melibe leonina Chemoecology. 12: 199-202. DOI: 10.1007/Pl00012669 |
0.767 |
|
| Show low-probability matches. |
