Bede Portz - Publications

Affiliations: 
2017- Biochemistry and Biophysics University of Pennsylvania, Philadelphia, PA, United States 

17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Sweeney KM, Chantarawong S, Barbieri EM, Cajka G, Liu M, Spruce L, Fazelinia H, Portz B, Copley K, Lapidot T, Duhamel L, Greenwald P, Saida N, Shalgi R, Shorter J, et al. CRISPR screen for protein inclusion formation uncovers a role for SRRD in the regulation of intermediate filament dynamics and aggresome assembly. Plos Genetics. 20: e1011138. PMID 38315730 DOI: 10.1371/journal.pgen.1011138  0.693
2024 Zhang Q, Kim W, Panina S, Mayfield JE, Portz B, Zhang YJ. Variation of C-terminal domain governs RNA polymerase II genomic locations and alternative splicing in eukaryotic transcription. Biorxiv : the Preprint Server For Biology. PMID 38260389 DOI: 10.1101/2024.01.01.573828  0.538
2023 Guo L, Mann JR, Mauna JC, Copley KE, Wang H, Rubien JD, Odeh HM, Lin J, Lee BL, Ganser L, Robinson E, Kim KM, Murthy AC, Paul T, Portz B, et al. Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domains. Biorxiv : the Preprint Server For Biology. PMID 37732211 DOI: 10.1101/2023.09.04.555754  0.658
2023 Boeynaems S, Chong S, Gsponer J, Holt L, Milovanovic D, Mitrea DM, Mueller-Cajar O, Portz B, Reilly JF, Reinkemeier CD, Sabari BR, Sanulli S, Shorter J, Sontag E, Strader L, et al. Phase Separation in Biology and Disease; Current Perspectives and Open Questions. Journal of Molecular Biology. 435: 167971. PMID 36690068 DOI: 10.1016/j.jmb.2023.167971  0.519
2021 Poudyal RR, Sieg JP, Portz B, Keating CD, Bevilacqua PC. RNA sequence and structure control assembly and function of RNA condensates. Rna (New York, N.Y.). PMID 34551999 DOI: 10.1261/rna.078875.121  0.58
2021 Hallegger M, Chakrabarti AM, Lee FCY, Lee BL, Amalietti AG, Odeh HM, Copley KE, Rubien JD, Portz B, Kuret K, Huppertz I, Rau F, Patani R, Fawzi NL, Shorter J, et al. TDP-43 condensation properties specify its RNA-binding and regulatory repertoire. Cell. PMID 34380047 DOI: 10.1016/j.cell.2021.07.018  0.736
2021 Portz B, Lee BL, Shorter J. FUS and TDP-43 Phases in Health and Disease. Trends in Biochemical Sciences. PMID 33446423 DOI: 10.1016/j.tibs.2020.12.005  0.625
2020 Portz B, Shorter J. Biochemical timekeeping via reentrant phase transitions. Journal of Molecular Biology. 166794. PMID 33387533 DOI: 10.1016/j.jmb.2020.166794  0.514
2020 Rubien JD, Portz B, Yatsunyk L, Carone D. RNA-Protein Phase Separation In Cancer: Investigating Human Satellite II RNA Structure And Function Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.1321  0.584
2019 Portz B, Shorter J. Switching Condensates: The CTD Code Goes Liquid. Trends in Biochemical Sciences. PMID 31734037 DOI: 10.1016/J.Tibs.2019.10.009  0.643
2019 Cheng W, Wang S, Zhang Z, Morgens DW, Hayes LR, Lee S, Portz B, Xie Y, Nguyen BV, Haney MS, Yan S, Dong D, Coyne AN, Yang J, Xian F, et al. CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation. Neuron. PMID 31587919 DOI: 10.1016/J.Neuron.2019.09.003  0.691
2019 Mann JR, Gleixner AM, Mauna JC, Gomes E, DeChellis-Marks MR, Needham PG, Copley KE, Hurtle B, Portz B, Pyles NJ, Guo L, Calder CB, Wills ZP, Pandey UB, Kofler JK, et al. RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43. Neuron. PMID 30826182 DOI: 10.1016/J.Neuron.2019.01.048  0.772
2019 Lu F, Portz B, Gilmour DS. The C-Terminal Domain of RNA Polymerase II Is a Multivalent Targeting Sequence that Supports Drosophila Development with Only Consensus Heptads. Molecular Cell. PMID 30765194 DOI: 10.1016/J.Molcel.2019.01.008  0.727
2018 Portz B, Shorter J. 3' UTRs in the Eye of the TIGER. Developmental Cell. 47: 544-546. PMID 30513300 DOI: 10.1016/J.Devcel.2018.11.022  0.55
2017 Gibbs EB, Laremore TN, Usher GA, Portz B, Cook EC, Showalter SA. Substrate Specificity of the Kinase P-TEFb towards the RNA Polymerase II C-Terminal Domain. Biophysical Journal. PMID 28992937 DOI: 10.1016/J.Bpj.2017.09.011  0.493
2017 Gibbs EB, Lu F, Portz B, Fisher MJ, Medellin BP, Laremore TN, Zhang YJ, Gilmour DS, Showalter SA. Phosphorylation induces sequence-specific conformational switches in the RNA polymerase II C-terminal domain. Nature Communications. 8: 15233. PMID 28497798 DOI: 10.1038/Ncomms15233  0.727
2017 Portz B, Lu F, Gibbs EB, Mayfield JE, Rachel Mehaffey M, Zhang YJ, Brodbelt JS, Showalter SA, Gilmour DS. Structural heterogeneity in the intrinsically disordered RNA polymerase II C-terminal domain. Nature Communications. 8: 15231. PMID 28497792 DOI: 10.1038/Ncomms15231  0.746
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