Edson X. Albuquerque - Publications

Affiliations: 
University of Maryland School of Medicine, Baltimore, MD, United States 

304 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Riggs LM, Aracava Y, Zanos P, Fischell J, Albuquerque EX, Pereira EFR, Thompson SM, Gould TD. (2R,6R)-hydroxynorketamine acts through a synapse-specific presynaptic mechanism to rapidly potentiate hippocampal glutamatergic transmission. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31216563 DOI: 10.1038/s41386-019-0443-3  0.44
2019 Lumsden EW, Troppoli TA, Myers SJ, Zanos P, Aracava Y, Kehr J, Lovett J, Kim S, Wang FH, Schmidt S, Jenne CE, Yuan P, Morris PJ, Thomas CJ, Zarate CA, ... ... Albuquerque EX, et al. Antidepressant-relevant concentrations of the ketamine metabolite (2,6)-hydroxynorketamine do not block NMDA receptor function. Proceedings of the National Academy of Sciences of the United States of America. PMID 30796190 DOI: 10.1073/pnas.1816071116  0.44
2018 Zanos P, Moaddel R, Morris PJ, Riggs LM, Highland JN, Georgiou P, Pereira EFR, Albuquerque EX, Thomas CJ, Zarate CA, Gould TD. Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms. Pharmacological Reviews. 70: 621-660. PMID 29945898 DOI: 10.1124/pr.117.015198  0.44
2017 Burke RD, Todd SW, Lumsden E, Mullins RJ, Mamczarz J, Fawcett WP, Gullapalli RP, Randall WR, Pereira EFR, Albuquerque EX. Developmental neurotoxicity of the organophosphorus insecticide chlorpyrifos: from clinical findings to preclinical models and potential mechanisms. Journal of Neurochemistry. 142: 162-177. PMID 28791702 DOI: 10.1111/jnc.14077  0.44
2016 Mamczarz J, Pescrille JD, Gavrushenko L, Burke RD, Fawcett WP, DeTolla LJ, Chen H, Pereira EF, Albuquerque EX. Spatial learning impairment in prepubertal guinea pigs prenatally exposed to the organophosphorus pesticide chlorpyrifos: Toxicological implications. Neurotoxicology. PMID 27296654 DOI: 10.1016/j.neuro.2016.06.008  0.36
2015 Mullins RJ, Xu S, Pereira EF, Pescrille JD, Todd SW, Mamczarz J, Albuquerque EX, Gullapalli RP. Prenatal exposure of guinea pigs to the organophosphorus pesticide chlorpyrifos disrupts the structural and functional integrity of the brain. Neurotoxicology. 48: 9-20. PMID 25704171 DOI: 10.1016/j.neuro.2015.02.002  1
2015 Alkondon M, Pereira EF, Todd SW, Randall WR, Lane MV, Albuquerque EX. Functional G-protein-coupled receptor 35 is expressed by neurons in the CA1 field of the hippocampus. Biochemical Pharmacology. 93: 506-18. PMID 25542997 DOI: 10.1016/j.bcp.2014.12.009  1
2014 Alexandrova EA, Alkondon M, Aracava Y, Pereira EF, Albuquerque EX. Galantamine prevents long-lasting suppression of excitatory synaptic transmission in CA1 pyramidal neurons of soman-challenged guinea pigs. Neurotoxicology. 44: 270-8. PMID 25064080 DOI: 10.1016/j.neuro.2014.07.005  1
2014 Pereira EF, Aracava Y, DeTolla LJ, Beecham EJ, Basinger GW, Wakayama EJ, Albuquerque EX. Animal models that best reproduce the clinical manifestations of human intoxication with organophosphorus compounds. The Journal of Pharmacology and Experimental Therapeutics. 350: 313-21. PMID 24907067 DOI: 10.1124/jpet.114.214932  1
2013 Banerjee J, Alkondon M, Albuquerque EX, Pereira EF. Contribution of CA3 and CA1 pyramidal neurons to the tonic α7 nAChR-dependent glutamatergic input to CA1 pyramidal neurons. Neuroscience Letters. 554: 167-71. PMID 23973303 DOI: 10.1016/j.neulet.2013.08.025  1
2013 Alkondon M, Albuquerque EX, Pereira EF. Acetylcholinesterase inhibition reveals endogenous nicotinic modulation of glutamate inputs to CA1 stratum radiatum interneurons in hippocampal slices. Neurotoxicology. 36: 72-81. PMID 23511125 DOI: 10.1016/j.neuro.2013.02.005  1
2013 Mullins RJ, Xu S, Pereira EF, Mamczarz J, Albuquerque EX, Gullapalli RP. Delayed hippocampal effects from a single exposure of prepubertal guinea pigs to sub-lethal dose of chlorpyrifos: a magnetic resonance imaging and spectroscopy study. Neurotoxicology. 36: 42-8. PMID 23411083 DOI: 10.1016/j.neuro.2013.02.002  1
2013 Albuquerque EX, Schwarcz R. Kynurenic acid as an antagonist of α7 nicotinic acetylcholine receptors in the brain: facts and challenges. Biochemical Pharmacology. 85: 1027-32. PMID 23270993 DOI: 10.1016/j.bcp.2012.12.014  1
2012 Banerjee J, Alkondon M, Albuquerque EX. Kynurenic acid inhibits glutamatergic transmission to CA1 pyramidal neurons via α7 nAChR-dependent and -independent mechanisms. Biochemical Pharmacology. 84: 1078-87. PMID 22889930 DOI: 10.1016/j.bcp.2012.07.030  1
2012 Banerjee J, Alkondon M, Pereira EF, Albuquerque EX. Regulation of GABAergic inputs to CA1 pyramidal neurons by nicotinic receptors and kynurenic acid. The Journal of Pharmacology and Experimental Therapeutics. 341: 500-9. PMID 22344459 DOI: 10.1124/jpet.111.189860  1
2011 Mamczarz J, Kulkarni GS, Pereira EF, Albuquerque EX. Galantamine counteracts development of learning impairment in guinea pigs exposed to the organophosphorus poison soman: clinical significance. Neurotoxicology. 32: 785-98. PMID 21784098 DOI: 10.1016/j.neuro.2011.07.001  1
2011 Alkondon M, Pereira EF, Albuquerque EX. Endogenous activation of nAChRs and NMDA receptors contributes to the excitability of CA1 stratum radiatum interneurons in rat hippocampal slices: effects of kynurenic acid. Biochemical Pharmacology. 82: 842-51. PMID 21689641 DOI: 10.1016/j.bcp.2011.06.004  1
2011 Alkondon M, Pereira EF, Eisenberg HM, Kajii Y, Schwarcz R, Albuquerque EX. Age dependency of inhibition of alpha7 nicotinic receptors and tonically active N-methyl-D-aspartate receptors by endogenously produced kynurenic acid in the brain. The Journal of Pharmacology and Experimental Therapeutics. 337: 572-82. PMID 21270133 DOI: 10.1124/jpet.110.177386  1
2010 Ludwig J, Höffle-Maas A, Samochocki M, Luttmann E, Albuquerque EX, Fels G, Maelicke A. Localization by site-directed mutagenesis of a galantamine binding site on α7 nicotinic acetylcholine receptor extracellular domain. Journal of Receptor and Signal Transduction Research. 30: 469-83. PMID 21062106 DOI: 10.3109/10799893.2010.505239  1
2010 Alexandrova EA, Aracava Y, Pereira EF, Albuquerque EX. Pretreatment of Guinea pigs with galantamine prevents immediate and delayed effects of soman on inhibitory synaptic transmission in the hippocampus. The Journal of Pharmacology and Experimental Therapeutics. 334: 1051-8. PMID 20554906 DOI: 10.1124/jpet.110.167700  1
2010 Potter MC, Elmer GI, Bergeron R, Albuquerque EX, Guidetti P, Wu HQ, Schwarcz R. Reduction of endogenous kynurenic acid formation enhances extracellular glutamate, hippocampal plasticity, and cognitive behavior. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 1734-42. PMID 20336058 DOI: 10.1038/npp.2010.39  1
2010 Mamczarz J, Pereira EF, Aracava Y, Adler M, Albuquerque EX. An acute exposure to a sub-lethal dose of soman triggers anxiety-related behavior in guinea pigs: interactions with acute restraint. Neurotoxicology. 31: 77-84. PMID 19883683 DOI: 10.1016/j.neuro.2009.10.012  1
2010 Gullapalli RP, Aracava Y, Zhuo J, Helal Neto E, Wang J, Makris G, Merchenthaler I, Pereira EF, Albuquerque EX. Magnetic resonance imaging reveals that galantamine prevents structural brain damage induced by an acute exposure of guinea pigs to soman. Neurotoxicology. 31: 67-76. PMID 19782102 DOI: 10.1016/j.neuro.2009.09.004  1
2010 Pereira EF, Aracava Y, Alkondon M, Akkerman M, Merchenthaler I, Albuquerque EX. Molecular and cellular actions of galantamine: clinical implications for treatment of organophosphorus poisoning. Journal of Molecular Neuroscience : Mn. 40: 196-203. PMID 19690988 DOI: 10.1007/s12031-009-9234-3  1
2010 Wu HQ, Pereira EF, Bruno JP, Pellicciari R, Albuquerque EX, Schwarcz R. The astrocyte-derived alpha7 nicotinic receptor antagonist kynurenic acid controls extracellular glutamate levels in the prefrontal cortex. Journal of Molecular Neuroscience : Mn. 40: 204-10. PMID 19690987 DOI: 10.1007/s12031-009-9235-2  1
2010 Karczmar AG, Albuquerque EX. Opening Session Journal of Molecular Neuroscience. 40: 1-6. DOI: 10.1007/s12031-009-9276-6  1
2009 Aracava Y, Pereira EF, Akkerman M, Adler M, Albuquerque EX. Effectiveness of donepezil, rivastigmine, and (+/-)huperzine A in counteracting the acute toxicity of organophosphorus nerve agents: comparison with galantamine. The Journal of Pharmacology and Experimental Therapeutics. 331: 1014-24. PMID 19741148 DOI: 10.1124/jpet.109.160028  1
2009 Albuquerque EX, Pereira EF, Alkondon M, Rogers SW. Mammalian nicotinic acetylcholine receptors: from structure to function. Physiological Reviews. 89: 73-120. PMID 19126755 DOI: 10.1152/physrev.00015.2008  1
2009 Fawcett WP, Aracava Y, Adler M, Pereira EF, Albuquerque EX. Acute toxicity of organophosphorus compounds in guinea pigs is sex- and age-dependent and cannot be solely accounted for by acetylcholinesterase inhibition. The Journal of Pharmacology and Experimental Therapeutics. 328: 516-24. PMID 18984651 DOI: 10.1124/jpet.108.146639  1
2009 Alkondon M, Aracava Y, Pereira EF, Albuquerque EX. A single in vivo application of cholinesterase inhibitors has neuron type-specific effects on nicotinic receptor activity in guinea pig hippocampus. The Journal of Pharmacology and Experimental Therapeutics. 328: 69-82. PMID 18842705 DOI: 10.1124/jpet.108.146068  1
2007 Alkondon M, Pereira EF, Albuquerque EX. Age-dependent changes in the functional expression of two nicotinic receptor subtypes in CA1 stratum radiatum interneurons in the rat hippocampus. Biochemical Pharmacology. 74: 1134-44. PMID 17645875 DOI: 10.1016/j.bcp.2007.06.023  1
2007 Lopes C, Pereira EF, Wu HQ, Purushottamachar P, Njar V, Schwarcz R, Albuquerque EX. Competitive antagonism between the nicotinic allosteric potentiating ligand galantamine and kynurenic acid at alpha7* nicotinic receptors. The Journal of Pharmacology and Experimental Therapeutics. 322: 48-58. PMID 17446300 DOI: 10.1124/jpet.107.123109  1
2007 Alkondon M, Pereira EF, Potter MC, Kauffman FC, Schwarcz R, Albuquerque EX. Strain-specific nicotinic modulation of glutamatergic transmission in the CA1 field of the rat hippocampus: August Copenhagen Irish versus Sprague-Dawley. Journal of Neurophysiology. 97: 1163-70. PMID 17151218 DOI: 10.1152/jn.01119.2006  1
2007 Guidetti P, Hoffman GE, Melendez-Ferro M, Albuquerque EX, Schwarcz R. Astrocytic localization of kynurenine aminotransferase II in the rat brain visualized by immunocytochemistry. Glia. 55: 78-92. PMID 17024659 DOI: 10.1002/glia.20432  1
2006 Popa RV, Pereira EF, Lopes C, Maelicke A, Albuquerque EX. The N-butylcarbamate derivative of galantamine acts as an allosteric potentiating ligand on alpha7 nicotinic receptors in hippocampal neurons: clinical implications for treatment of Alzheimer's disease. Journal of Molecular Neuroscience : Mn. 30: 227-32. PMID 17192682 DOI: 10.1385/JMN:30:1:227  1
2006 Albuquerque EX, Pereira EF, Aracava Y, Fawcett WP, Oliveira M, Randall WR, Hamilton TA, Kan RK, Romano JA, Adler M. Effective countermeasure against poisoning by organophosphorus insecticides and nerve agents. Proceedings of the National Academy of Sciences of the United States of America. 103: 13220-5. PMID 16914529 DOI: 10.1073/pnas.0605370103  1
2006 Santos HR, Ribeiro HS, Setti-Perdigão P, Albuquerque EX, Castro NG. The magnitude of alpha7 nicotinic receptor currents in rat hippocampal neurons is dependent upon GABAergic activity and depolarization. The Journal of Pharmacology and Experimental Therapeutics. 319: 376-85. PMID 16837558 DOI: 10.1124/jpet.106.106385  1
2006 Alkondon M, Albuquerque EX. Subtype-specific inhibition of nicotinic acetylcholine receptors by choline: a regulatory pathway. The Journal of Pharmacology and Experimental Therapeutics. 318: 268-75. PMID 16565162 DOI: 10.1124/jpet.106.103135  1
2005 Banerjee P, Samoriski G, Gupta S, Aracava Y, Pereira EFR, Maelicke A, Albuquerque EX. Comments on "memantine blocks α7* nicotinic acetylcholine receptors more potently than N-methyl-D-aspartate receptors in rat hippocampal neurons" (multiple letters) Journal of Pharmacology and Experimental Therapeutics. 313: 928-933. PMID 15831445 DOI: 10.1124/jpet.104.081976  1
2005 Alkondon M, Albuquerque EX. Nicotinic receptor subtypes in rat hippocampal slices are differentially sensitive to desensitization and early in vivo functional up-regulation by nicotine and to block by bupropion. The Journal of Pharmacology and Experimental Therapeutics. 313: 740-50. PMID 15647329 DOI: 10.1124/jpet.104.081232  1
2005 Aracava Y, Pereira EF, Maelicke A, Albuquerque EX. Memantine blocks alpha7* nicotinic acetylcholine receptors more potently than n-methyl-D-aspartate receptors in rat hippocampal neurons. The Journal of Pharmacology and Experimental Therapeutics. 312: 1195-205. PMID 15522999 DOI: 10.1124/jpet.104.077172  1
2005 Rassoulpour A, Wu HQ, Albuquerque EX, Schwarcz R. Prolonged nicotine administration results in biphasic, brain-specific changes in kynurenate levels in the rat. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 697-704. PMID 15496939 DOI: 10.1038/sj.npp.1300583  1
2004 Braga MF, Pereira EF, Mike A, Albuquerque EX. Pb2+ via protein kinase C inhibits nicotinic cholinergic modulation of synaptic transmission in the hippocampus. The Journal of Pharmacology and Experimental Therapeutics. 311: 700-10. PMID 15226386 DOI: 10.1124/jpet.104.070466  1
2004 Alkondon M, Pereira EF, Yu P, Arruda EZ, Almeida LE, Guidetti P, Fawcett WP, Sapko MT, Randall WR, Schwarcz R, Tagle DA, Albuquerque EX. Targeted deletion of the kynurenine aminotransferase ii gene reveals a critical role of endogenous kynurenic acid in the regulation of synaptic transmission via alpha7 nicotinic receptors in the hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4635-48. PMID 15140935 DOI: 10.1523/JNEUROSCI.5631-03.2004  1
2004 Almeida LE, Pereira EF, Camara AL, Maelicke A, Albuquerque EX. Sensitivity of neuronal nicotinic acetylcholine receptors to the opiate antagonists naltrexone and naloxone: receptor blockade and up-regulation. Bioorganic & Medicinal Chemistry Letters. 14: 1879-87. PMID 15050620 DOI: 10.1016/j.bmcl.2004.01.004  1
2004 Santos HR, Cintra WM, Aracava Y, Maciel CM, Castro NG, Albuquerque EX. Spine density and dendritic branching pattern of hippocampal CA1 pyramidal neurons in neonatal rats chronically exposed to the organophosphate paraoxon. Neurotoxicology. 25: 481-94. PMID 15019311 DOI: 10.1016/j.neuro.2004.01.007  1
2004 Alkondon M, Albuquerque EX. The nicotinic acetylcholine receptor subtypes and their function in the hippocampus and cerebral cortex. Progress in Brain Research. 145: 109-20. PMID 14650910 DOI: 10.1016/S0079-6123(03)45007-3  1
2003 Menegatti R, Cunha AC, Ferreira VF, Perreira EF, El-Nabawi A, Eldefrawi AT, Albuquerque EX, Neves G, Rates SM, Fraga CA, Barreiro EJ. Design, synthesis and pharmacological profile of novel dopamine D2 receptor ligands. Bioorganic & Medicinal Chemistry. 11: 4807-13. PMID 14556797 DOI: 10.1016/S0968-0896(03)00487-5  1
2003 Alkondon M, Pereira EF, Albuquerque EX. NMDA and AMPA receptors contribute to the nicotinic cholinergic excitation of CA1 interneurons in the rat hippocampus. Journal of Neurophysiology. 90: 1613-25. PMID 12702709 DOI: 10.1152/jn.00214.2003  1
2003 Samochocki M, Höffle A, Fehrenbacher A, Jostock R, Ludwig J, Christner C, Radina M, Zerlin M, Ullmer C, Pereira EF, Lübbert H, Albuquerque EX, Maelicke A. Galantamine is an allosterically potentiating ligand of neuronal nicotinic but not of muscarinic acetylcholine receptors. The Journal of Pharmacology and Experimental Therapeutics. 305: 1024-36. PMID 12649296 DOI: 10.1124/jpet.102.045773  1
2003 Santos MD, Pereira EF, Aracava Y, Castro NG, Fawcett WP, Randall WR, Albuquerque EX. Low concentrations of pyridostigmine prevent soman-induced inhibition of GABAergic transmission in the central nervous system: involvement of muscarinic receptors. The Journal of Pharmacology and Experimental Therapeutics. 304: 254-65. PMID 12490599 DOI: 10.1124/jpet.102.043109  1
2002 Pereira EF, Hilmas C, Santos MD, Alkondon M, Maelicke A, Albuquerque EX. Unconventional ligands and modulators of nicotinic receptors. Journal of Neurobiology. 53: 479-500. PMID 12436414 DOI: 10.1002/neu.10146  1
2002 Priel MR, Albuquerque EX. Short-term effects of pilocarpine on rat hippocampal neurons in culture. Epilepsia. 43: 40-6. PMID 12121294 DOI: 10.1046/j.1528-1157.2002.043s1040.x  1
2002 Santos MD, Alkondon M, Pereira EF, Aracava Y, Eisenberg HM, Maelicke A, Albuquerque EX. The nicotinic allosteric potentiating ligand galantamine facilitates synaptic transmission in the mammalian central nervous system. Molecular Pharmacology. 61: 1222-34. PMID 11961141 DOI: 10.1124/mol.61.5.1222  1
2002 Alkondon M, Albuquerque EX. A non-alpha7 nicotinic acetylcholine receptor modulates excitatory input to hippocampal CA1 interneurons. Journal of Neurophysiology. 87: 1651-4. PMID 11877536  1
2001 Alkondon M, Albuquerque EX. Nicotinic acetylcholine receptor alpha7 and alpha4beta2 subtypes differentially control GABAergic input to CA1 neurons in rat hippocampus. Journal of Neurophysiology. 86: 3043-55. PMID 11731559  1
2001 Wang Y, Pereira EF, Maus AD, Ostlie NS, Navaneetham D, Lei S, Albuquerque EX, Conti-Fine BM. Human bronchial epithelial and endothelial cells express alpha7 nicotinic acetylcholine receptors. Molecular Pharmacology. 60: 1201-9. PMID 11723227  1
2001 Albuquerque EX, Santos MD, Alkondon M, Pereira EF, Maelicke A. Modulation of nicotinic receptor activity in the central nervous system: a novel approach to the treatment of Alzheimer disease. Alzheimer Disease and Associated Disorders. 15: S19-25. PMID 11669505  1
2001 Gonzalez-Serratos H, Chang R, Pereira EF, Castro NG, Aracava Y, Melo PA, Lima PC, Fraga CA, Barreiro EJ, Albuquerque EX. A novel thienylhydrazone, (2-thienylidene)3,4-methylenedioxybenzoylhydrazine, increases inotropism and decreases fatigue of skeletal muscle. The Journal of Pharmacology and Experimental Therapeutics. 299: 558-66. PMID 11602667  1
2001 Hilmas C, Pereira EF, Alkondon M, Rassoulpour A, Schwarcz R, Albuquerque EX. The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increases non-alpha7 nicotinic receptor expression: physiopathological implications. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 7463-73. PMID 11567036  1
2001 Maelicke A, Samochocki M, Jostock R, Fehrenbacher A, Ludwig J, Albuquerque EX, Zerlin M. Allosteric sensitization of nicotinic receptors by galantamine, a new treatment strategy for Alzheimer's disease. Biological Psychiatry. 49: 279-88. PMID 11230879 DOI: 10.1016/S0006-3223(00)01109-4  1
2001 da Silva AJM, Melo PA, Silva NM, Brito FV, Buarque CD, de Souza DV, Rodrigues VP, Poças ES, Noël F, Albuquerque EX, Costa PR. Synthesis and preliminary pharmacological evaluation of coumestans with different patterns of oxygenation. Bioorganic & Medicinal Chemistry Letters. 11: 283-6. PMID 11212092 DOI: 10.1016/S0960-894X(00)00621-1  1
2001 Peçanha EP, Fraga CAM, Barreiro EJ, Braga MFM, Pereira EFR, Albuquerque EX. Synthesis and Pharmacological Evaluation of a New 2-Azabicyclo[3.3.0]octane Derivative Journal of the Brazilian Chemical Society. 12: 408-412.  1
2000 Samochocki M, Zerlin M, Jostock R, Groot Kormelink PJ, Luyten WH, Albuquerque EX, Maelicke A. Galantamine is an allosterically potentiating ligand of the human alpha4/beta2 nAChR. Acta Neurologica Scandinavica. Supplementum. 176: 68-73. PMID 11261808  1
2000 Mike A, Castro NG, Albuquerque EX. Choline and acetylcholine have similar kinetic properties of activation and desensitization on the alpha7 nicotinic receptors in rat hippocampal neurons. Brain Research. 882: 155-68. PMID 11056195 DOI: 10.1016/S0006-8993(00)02863-8  1
2000 Almeida LE, Pereira EF, Alkondon M, Fawcett WP, Randall WR, Albuquerque EX. The opioid antagonist naltrexone inhibits activity and alters expression of alpha7 and alpha4beta2 nicotinic receptors in hippocampal neurons: implications for smoking cessation programs. Neuropharmacology. 39: 2740-55. PMID 11044744 DOI: 10.1016/S0028-3908(00)00157-X  1
2000 Alkondon M, Pereira EF, Almeida LE, Randall WR, Albuquerque EX. Nicotine at concentrations found in cigarette smokers activates and desensitizes nicotinic acetylcholine receptors in CA1 interneurons of rat hippocampus. Neuropharmacology. 39: 2726-39. PMID 11044743 DOI: 10.1016/S0028-3908(00)00156-8  1
2000 Maelicke A, Schrattenholz A, Samochocki M, Radina M, Albuquerque EX. Allosterically potentiating ligands of nicotinic receptors as a treatment strategy for Alzheimer's disease. Behavioural Brain Research. 113: 199-206. PMID 10942046 DOI: 10.1016/S0166-4328(00)00214-X  1
2000 Albuquerque EX, Pereira EF, Mike A, Eisenberg HM, Maelicke A, Alkondon M. Neuronal nicotinic receptors in synaptic functions in humans and rats: physiological and clinical relevance. Behavioural Brain Research. 113: 131-41. PMID 10942040 DOI: 10.1016/S0166-4328(00)00208-4  1
2000 Mike A, Pereira EF, Albuquerque EX. Ca(2+)-sensitive inhibition by Pb(2+) of alpha7-containing nicotinic acetylcholine receptors in hippocampal neurons. Brain Research. 873: 112-23. PMID 10915816 DOI: 10.1016/S0006-8993(00)02533-6  1
2000 Maelicke A, Albuquerque EX. Allosteric modulation of nicotinic acetylcholine receptors as a treatment strategy for Alzheimer's disease. European Journal of Pharmacology. 393: 165-70. PMID 10771010 DOI: 10.1016/S0014-2999(00)00093-5  1
2000 Alkondon M, Braga MF, Pereira EF, Maelicke A, Albuquerque EX. alpha7 nicotinic acetylcholine receptors and modulation of gabaergic synaptic transmission in the hippocampus. European Journal of Pharmacology. 393: 59-67. PMID 10770998 DOI: 10.1016/S0014-2999(00)00006-6  1
2000 Alkondon M, Pereira EF, Eisenberg HM, Albuquerque EX. Nicotinic receptor activation in human cerebral cortical interneurons: a mechanism for inhibition and disinhibition of neuronal networks. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 66-75. PMID 10627582  1
1999 Chebabo SR, Santos MD, Albuquerque EX. The organophosphate sarin, at low concentrations, inhibits the evoked release of GABA in rat hippocampal slices. Neurotoxicology. 20: 871-82. PMID 10693968  1
1999 Fischer U, Reinhardt S, Albuquerque EX, Maelicke A. Expression of functional alpha7 nicotinic acetylcholine receptor during mammalian muscle development and denervation. The European Journal of Neuroscience. 11: 2856-64. PMID 10457182 DOI: 10.1046/j.1460-9568.1999.00703.x  1
1999 Rocha ES, Santos MD, Chebabo SR, Aracava Y, Albuquerque EX. Low concentrations of the organophosphate VX affect spontaneous and evoked transmitter release from hippocampal neurons: toxicological relevance of cholinesterase-independent actions. Toxicology and Applied Pharmacology. 159: 31-40. PMID 10448123 DOI: 10.1006/taap.1999.8733  1
1999 Wevers A, Monteggia L, Nowacki S, Bloch W, Schütz U, Lindstrom J, Pereira EF, Eisenberg H, Giacobini E, de Vos RA, Steur EN, Maelicke A, Albuquerque EX, Schröder H. Expression of nicotinic acetylcholine receptor subunits in the cerebral cortex in Alzheimer's disease: histotopographical correlation with amyloid plaques and hyperphosphorylated-tau protein. The European Journal of Neuroscience. 11: 2551-65. PMID 10383644 DOI: 10.1046/j.1460-9568.1999.00676.x  1
1999 Lukas RJ, Changeux JP, Le Novère N, Albuquerque EX, Balfour DJ, Berg DK, Bertrand D, Chiappinelli VA, Clarke PB, Collins AC, Dani JA, Grady SR, Kellar KJ, Lindstrom JM, Marks MJ, et al. International Union of Pharmacology. XX. Current status of the nomenclature for nicotinic acetylcholine receptors and their subunits. Pharmacological Reviews. 51: 397-401. PMID 10353988  1
1999 Braga MF, Pereira EF, Albuquerque EX. Nanomolar concentrations of lead inhibit glutamatergic and GABAergic transmission in hippocampal neurons. Brain Research. 826: 22-34. PMID 10216193 DOI: 10.1016/S0006-8993(99)01194-4  1
1999 Braga MF, Pereira EF, Marchioro M, Albuquerque EX. Lead increases tetrodotoxin-insensitive spontaneous release of glutamate and GABA from hippocampal neurons. Brain Research. 826: 10-21. PMID 10216192 DOI: 10.1016/S0006-8993(99)01193-2  1
1999 Alkondon M, Pereira EF, Eisenberg HM, Albuquerque EX. Choline and selective antagonists identify two subtypes of nicotinic acetylcholine receptors that modulate GABA release from CA1 interneurons in rat hippocampal slices. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 2693-705. PMID 10087082  1
1998 Rocha ES, Chebabo SR, Santos MD, Aracava Y, Albuquerque EX. An analysis of low level doses of cholinesterase inhibitors in cultured neurons and hippocampal slices of rats. Drug and Chemical Toxicology. 21: 191-200. PMID 10028411 DOI: 10.3109/01480549809007411  1
1998 Albuquerque EX, Pereira EF, Braga MF, Matsubayashi H, Alkondon M. Neuronal nicotinic receptors modulate synaptic function in the hippocampus and are sensitive to blockade by the convulsant strychnine and by the anti-Parkinson drug amantadine. Toxicology Letters. 102: 211-8. PMID 10022256 DOI: 10.1016/S0378-4274(98)00309-9  1
1998 Alkondon M, Pereira EF, Albuquerque EX. alpha-bungarotoxin- and methyllycaconitine-sensitive nicotinic receptors mediate fast synaptic transmission in interneurons of rat hippocampal slices. Brain Research. 810: 257-63. PMID 9813357 DOI: 10.1016/S0006-8993(98)00880-4  1
1998 Maus AD, Pereira EF, Karachunski PI, Horton RM, Navaneetham D, Macklin K, Cortes WS, Albuquerque EX, Conti-Fine BM. Human and rodent bronchial epithelial cells express functional nicotinic acetylcholine receptors. Molecular Pharmacology. 54: 779-88. PMID 9804613  1
1998 Albuquerque EX, Pereira EF, Braga MF, Alkondon M. Contribution of nicotinic receptors to the function of synapses in the central nervous system: the action of choline as a selective agonist of alpha 7 receptors. Journal of Physiology, Paris. 92: 309-16. PMID 9789829 DOI: 10.1016/S0928-4257(98)80039-9  1
1998 Macklin KD, Maus AD, Pereira EF, Albuquerque EX, Conti-Fine BM. Human vascular endothelial cells express functional nicotinic acetylcholine receptors. The Journal of Pharmacology and Experimental Therapeutics. 287: 435-9. PMID 9765366  1
1998 Matsubayashi H, Alkondon M, Pereira EF, Swanson KL, Albuquerque EX. Strychnine: a potent competitive antagonist of alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors in rat hippocampal neurons. The Journal of Pharmacology and Experimental Therapeutics. 284: 904-13. PMID 9495848  1
1997 Alkondon M, Pereira EF, Cortes WS, Maelicke A, Albuquerque EX. Choline is a selective agonist of alpha7 nicotinic acetylcholine receptors in the rat brain neurons. The European Journal of Neuroscience. 9: 2734-42. PMID 9517478 DOI: 10.1111/j.1460-9568.1997.tb01702.x  1
1997 Alkondon M, Pereira EF, Barbosa CT, Albuquerque EX. Neuronal nicotinic acetylcholine receptor activation modulates gamma-aminobutyric acid release from CA1 neurons of rat hippocampal slices. The Journal of Pharmacology and Experimental Therapeutics. 283: 1396-411. PMID 9400016  1
1997 Camara AL, Braga MF, Rocha ES, Santos MD, Cortes WS, Cintra WM, Aracava Y, Maelicke A, Albuguergue EX. Methamidophos: an anticholinesterase without significant effects on postsynaptic receptors or transmitter release. Neurotoxicology. 18: 589-602. PMID 9291508  1
1997 Matsubayashi H, Swanson KL, Albuquerque EX. Amantadine inhibits nicotinic acetylcholine receptor function in hippocampal neurons. The Journal of Pharmacology and Experimental Therapeutics. 281: 834-44. PMID 9152392  1
1997 Albuquerque EX, Alkondon M, Pereira EF, Castro NG, Schrattenholz A, Barbosa CT, Bonfante-Cabarcas R, Aracava Y, Eisenberg HM, Maelicke A. Properties of neuronal nicotinic acetylcholine receptors: pharmacological characterization and modulation of synaptic function. The Journal of Pharmacology and Experimental Therapeutics. 280: 1117-36. PMID 9067295  1
1997 Albuquerque EX, Pereira EF, Alkondon M, Schrattenholz A, Maelicke A. Nicotinic acetylcholine receptors on hippocampal neurons: distribution on the neuronal surface and modulation of receptor activity. Journal of Receptor and Signal Transduction Research. 17: 243-66. PMID 9029494 DOI: 10.3109/10799899709036607  1
1997 Maelicke A, Coban T, Storch A, Schrattenholz A, Pereira EF, Albuquerque EX. Allosteric modulation of Torpedo nicotinic acetylcholine receptor ion channel activity by noncompetitive agonists. Journal of Receptor and Signal Transduction Research. 17: 11-28. PMID 9029479 DOI: 10.3109/10799899709036592  1
1996 Albuquerque EX, Pereira EF, Bonfante-Cabarcas R, Marchioro M, Matsubayashi H, Alkondon M, Maelicke A. Nicotinic acetylcholine receptors on hippocampal neurons: cell compartment-specific expression and modulatory control of channel activity. Progress in Brain Research. 109: 111-24. PMID 9009698  1
1996 Alkondon M, Pereira EF, Albuquerque EX. Mapping the location of functional nicotinic and gamma-aminobutyric acidA receptors on hippocampal neurons. The Journal of Pharmacology and Experimental Therapeutics. 279: 1491-506. PMID 8968375  1
1996 Marchioro M, Swanson KL, Aracava Y, Albuquerque EX. Glycine and calcium-dependent effects of lead on N-methyl-D-aspartate receptor function in rat hippocampal neurons. The Journal of Pharmacology and Experimental Therapeutics. 279: 143-53. PMID 8858987  1
1996 Pereira EF, Alkondon M, McIntosh JM, Albuquerque EX. Alpha-conotoxin-ImI: a competitive antagonist at alpha-bungarotoxin-sensitive neuronal nicotinic receptors in hippocampal neurons. The Journal of Pharmacology and Experimental Therapeutics. 278: 1472-83. PMID 8819535  1
1996 Alkondon M, Rocha ES, Maelicke A, Albuquerque EX. Diversity of nicotinic acetylcholine receptors in rat brain. V. alpha-Bungarotoxin-sensitive nicotinic receptors in olfactory bulb neurons and presynaptic modulation of glutamate release. The Journal of Pharmacology and Experimental Therapeutics. 278: 1460-71. PMID 8819534  1
1996 Rocha ES, Swanson KL, Aracava Y, Goolsby JE, Maelicke A, Albuquerque EX. Paraoxon: cholinesterase-independent stimulation of transmitter release and selective block of ligand-gated ion channels in cultured hippocampal neurons. The Journal of Pharmacology and Experimental Therapeutics. 278: 1175-87. PMID 8819500  1
1996 Barbosa CT, Alkondon M, Aracava Y, Maelicke A, Albuquerque EX. Ligand-gated ion channels in acutely dissociated rat hippocampal neurons with long dendrites. Neuroscience Letters. 210: 177-80. PMID 8805124 DOI: 10.1016/0304-3940(96)12679-3  1
1996 Bonfante-Cabarcas R, Swanson KL, Alkondon M, Albuquerque EX. Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. IV. Regulation by external Ca++ of alpha-bungarotoxin-sensitive receptor function and of rectification induced by internal Mg++. The Journal of Pharmacology and Experimental Therapeutics. 277: 432-44. PMID 8613952  1
1996 Schrattenholz A, Pereira EF, Roth U, Weber KH, Albuquerque EX, Maelicke A. Agonist responses of neuronal nicotinic acetylcholine receptors are potentiated by a novel class of allosterically acting ligands. Molecular Pharmacology. 49: 1-6. PMID 8569694  1
1996 Maelicke A, Albuquerque EX. New approach to drug therapy in Alzheimer's dementia Drug Discovery Today. 1: 53-59. DOI: 10.1016/1359-6446(96)89089-1  1
1995 Maelicke A, Schrattenholz A, Storch A, Schroder B, Gutbrod O, Methfessel C, Weber KH, Pereira EE, Alkondon M, Albuquerque EX. Noncompetitive agonism at nicotinic acetylcholine receptors; functional significance for CNS signal transduction. Journal of Receptor and Signal Transduction Research. 15: 333-53. PMID 8903949 DOI: 10.3109/10799899509045225  1
1995 Ishihara K, Alkondon M, Montes JG, Albuquerque EX. Nicotinic responses in acutely dissociated rat hippocampal neurons and the selective blockade of fast-desensitizing nicotinic currents by lead. The Journal of Pharmacology and Experimental Therapeutics. 273: 1471-82. PMID 7791122  1
1995 Ishihara K, Alkondon M, Montes JG, Albuquerque EX. Ontogenically related properties of N-methyl-D-aspartate receptors in rat hippocampal neurons and the age-specific sensitivity of developing neurons to lead. The Journal of Pharmacology and Experimental Therapeutics. 273: 1459-70. PMID 7791121  1
1995 Castro NG, Albuquerque EX. alpha-Bungarotoxin-sensitive hippocampal nicotinic receptor channel has a high calcium permeability. Biophysical Journal. 68: 516-24. PMID 7696505 DOI: 10.1016/S0006-3495(95)80213-4  1
1995 Albuquerque EX, Pereira EF, Castro NG, Alkondon M, Reinhardt S, Schröder H, Maelicke A. Nicotinic receptor function in the mammalian central nervous system. Annals of the New York Academy of Sciences. 757: 48-72. PMID 7611705 DOI: 10.1111/j.1749-6632.1995.tb17464.x  1
1995 Storch A, Schrattenholz A, Cooper JC, Abdel Ghani EM, Gutbrod O, Weber KH, Reinhardt S, Lobron C, Hermsen B, Soskiç V. Physostigmine, galanthamine and codeine act as 'noncompetitive nicotinic receptor agonists' on clonal rat pheochromocytoma cells. European Journal of Pharmacology. 290: 207-19. PMID 7589215 DOI: 10.1016/0922-4106(95)00080-1  1
1995 Alkondon M, Albuquerque EX. Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. III. Agonist actions of the novel alkaloid epibatidine and analysis of type II current. The Journal of Pharmacology and Experimental Therapeutics. 274: 771-82. PMID 7543571  1
1995 Grando SA, Horton RM, Pereira EF, Diethelm-Okita BM, George PM, Albuquerque EX, Conti-Fine BM. A nicotinic acetylcholine receptor regulating cell adhesion and motility is expressed in human keratinocytes. The Journal of Investigative Dermatology. 105: 774-81. PMID 7490471  1
1995 Albuquerque EX, Pereira EFR, Castro NG, Alkondon M. Neuronal nicotinic receptors: Function, modulation and structure Seminars in the Neurosciences. 7: 91-101. DOI: 10.1006/smns.1995.0011  1
1994 Schrattenholz A, Roth U, Schuhen A, Schäfer HJ, Godovac-Zimmermann J, Albuquerque EX, Maelicke A. Identification of purine binding sites on Torpedo acetylcholine receptor. Journal of Receptor Research. 14: 197-208. PMID 8083864 DOI: 10.3109/10799899409066031  1
1994 Pereira EF, Alkondon M, Reinhardt S, Maelicke A, Peng X, Lindstrom J, Whiting P, Albuquerque EX. Physostigmine and galanthamine: probes for a novel binding site on the alpha 4 beta 2 subtype of neuronal nicotinic acetylcholine receptors stably expressed in fibroblast cells. The Journal of Pharmacology and Experimental Therapeutics. 270: 768-78. PMID 8071869  1
1994 Alkondon M, Albuquerque EX. Presence of alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors in rat olfactory bulb neurons. Neuroscience Letters. 176: 152-6. PMID 7830936 DOI: 10.1016/0304-3940(94)90070-1  1
1994 Alkondon M, Reinhardt S, Lobron C, Hermsen B, Maelicke A, Albuquerque EX. Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. II. The rundown and inward rectification of agonist-elicited whole-cell currents and identification of receptor subunits by in situ hybridization. The Journal of Pharmacology and Experimental Therapeutics. 271: 494-506. PMID 7525930  1
1994 Nelson ME, Albuquerque EX. 9-Aminoacridines act at a site different from that for Mg2+ in blockade of the N-methyl-D-aspartate receptor channel. Molecular Pharmacology. 46: 151-60. PMID 7520125  1
1994 Costa AC, Albuquerque EX. Dynamics of the actions of tetrahydro-9-aminoacridine and 9-aminoacridine on glutamatergic currents: concentration-jump studies in cultured rat hippocampal neurons. The Journal of Pharmacology and Experimental Therapeutics. 268: 503-14. PMID 7507997  1
1993 Pereira EF, Reinhardt-Maelicke S, Schrattenholz A, Maelicke A, Albuquerque EX. Identification and functional characterization of a new agonist site on nicotinic acetylcholine receptors of cultured hippocampal neurons. The Journal of Pharmacology and Experimental Therapeutics. 265: 1474-91. PMID 8510023  1
1993 Alkondon M, Albuquerque EX. Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. I. Pharmacological and functional evidence for distinct structural subtypes. The Journal of Pharmacology and Experimental Therapeutics. 265: 1455-73. PMID 8510022  1
1993 Thomas P, Stephens M, Wilkie G, Amar M, Lunt GG, Whiting P, Gallagher T, Pereira E, Alkondon M, Albuquerque EX. (+)-Anatoxin-a is a potent agonist at neuronal nicotinic acetylcholine receptors. Journal of Neurochemistry. 60: 2308-11. PMID 8492133  1
1993 Pereira EF, Alkondon M, Tano T, Castro NG, Fróes-Ferrão MM, Rozental R, Aronstam RS, Schrattenholz A, Maelicke A, Albuquerque EX. A novel agonist binding site on nicotinic acetylcholine receptors. Journal of Receptor Research. 13: 413-36. PMID 8450498 DOI: 10.3109/10799899309073670  1
1993 Maelicke A, Coban T, Schrattenholz A, Schröder B, Reinhardt-Maelicke S, Storch A, Godovac-Zimmermann J, Methfessel C, Pereira EF, Albuquerque EX. Physostigmine and neuromuscular transmission. Annals of the New York Academy of Sciences. 681: 140-54. PMID 8395146  1
1993 Good JL, Khurana RK, Mayer RF, Cintra WM, Albuquerque EX. Pathophysiological studies of neuromuscular function in subacute organophosphate poisoning induced by phosmet. Journal of Neurology, Neurosurgery, and Psychiatry. 56: 290-4. PMID 8384655  1
1993 Schrattenholz A, Godovac-Zimmermann J, Schäfer HJ, Albuquerque EX, Maelicke A. Photoaffinity labeling of Torpedo acetylcholine receptor by physostigmine. European Journal of Biochemistry / Febs. 216: 671-7. PMID 8375401  1
1993 Cestari IN, Albuquerque EX, Burt DR. A PCR shortcut to oocyte expression. Biotechniques. 14: 404-7. PMID 7681299  1
1993 Schrattenholz A, Coban T, Schröder B, Okonjo KO, Kuhlmann J, Pereira EF, Albuquerque EX, Maelicke A. Biochemical characterization of a novel channel-activating site on nicotinic acetylcholine receptors. Journal of Receptor Research. 13: 393-412. PMID 7680720 DOI: 10.3109/10799899309073669  1
1993 Castro NG, Albuquerque EX. Brief-lifetime, fast-inactivating ion channels account for the alpha-bungarotoxin-sensitive nicotinic response in hippocampal neurons. Neuroscience Letters. 164: 137-40. PMID 7512242 DOI: 10.1016/0304-3940(93)90876-M  1
1992 Swanson KL, Albuquerque EX. Progress in understanding the nicotinic acetylcholine receptor function at central and peripheral nervous system synapses through toxin interactions. Maryland Medical Journal (Baltimore, Md. : 1985). 41: 623-31. PMID 1640819  1
1992 Stolerman IP, Albuquerque EX, Garcha HS. Behavioural effects of anatoxin, a potent nicotinic agonist, in rats. Neuropharmacology. 31: 311-4. PMID 1630597 DOI: 10.1016/0028-3908(92)90182-O  1
1992 Alkondon M, Pereira EF, Wonnacott S, Albuquerque EX. Blockade of nicotinic currents in hippocampal neurons defines methyllycaconitine as a potent and specific receptor antagonist. Molecular Pharmacology. 41: 802-8. PMID 1569927  1
1992 Adler M, Deshpande SS, Foster RE, Maxwell DM, Albuquerque EX. Effects of subacute pyridostigmine administration on mammalian skeletal muscle function. Journal of Applied Toxicology : Jat. 12: 25-33. PMID 1564249 DOI: 10.1002/jat.2550120107  1
1992 Wonnacott S, Swanson KL, Albuquerque EX, Huby NJ, Thompson P, Gallagher T. Homoanatoxin: a potent analogue of anatoxin-A. Biochemical Pharmacology. 43: 419-23. PMID 1540199 DOI: 10.1016/0006-2952(92)90558-Z  1
1992 Ujihara H, Albuquerque EX. Developmental change of the inhibition by lead of NMDA-activated currents in cultured hippocampal neurons. The Journal of Pharmacology and Experimental Therapeutics. 263: 868-75. PMID 1432703  1
1992 Ujihara H, Albuquerque EX. Ontogeny of N-methyl-D-aspartate-induced current in cultured hippocampal neurons. The Journal of Pharmacology and Experimental Therapeutics. 263: 859-67. PMID 1432702  1
1992 Pereira EF, Aracava Y, Aronstam RS, Barreiro EJ, Albuquerque EX. Pyrazole, an alcohol dehydrogenase inhibitor, has dual effects on N-methyl-D-aspartate receptors of hippocampal pyramidal cells: agonist and noncompetitive antagonist. The Journal of Pharmacology and Experimental Therapeutics. 261: 331-40. PMID 1313873  1
1991 Kawabuchi M, Cintra WM, Deshpande SS, Albuquerque EX. Morphological and electrophysiological study of distal motor nerve fiber degeneration and sprouting after irreversible cholinesterase inhibition. Synapse (New York, N.Y.). 8: 218-28. PMID 1948671 DOI: 10.1002/syn.890080308  1
1991 Wonnacott S, Jackman S, Swanson KL, Rapoport H, Albuquerque EX. Nicotinic pharmacology of anatoxin analogs. II. Side chain structure-activity relationships at neuronal nicotinic ligand binding sites. The Journal of Pharmacology and Experimental Therapeutics. 259: 387-91. PMID 1920126  1
1991 Swanson KL, Aronstam RS, Wonnacott S, Rapoport H, Albuquerque EX. Nicotinic pharmacology of anatoxin analogs. I. Side chain structure-activity relationships at peripheral agonist and noncompetitive antagonist sites. The Journal of Pharmacology and Experimental Therapeutics. 259: 377-86. PMID 1920124  1
1991 Reddy VK, Deshpande SS, Cintra WM, Scoble GT, Albuquerque EX. Effectiveness of oximes 2-PAM and HI-6 in recovery of muscle function depressed by organophosphate agents in the rat hemidiaphragm: an in vitro study. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 17: 746-60. PMID 1778361 DOI: 10.1093/toxsci/17.4.746  1
1991 Alkondon M, Albuquerque EX. Initial characterization of the nicotinic acetylcholine receptors in rat hippocampal neurons. Journal of Receptor Research. 11: 1001-21. PMID 1753378 DOI: 10.3109/10799899109064693  1
1991 Albuquerque EX, Costa AC, Alkondon M, Shaw KP, Ramoa AS, Aracava Y. Functional properties of the nicotinic and glutamatergic receptors. Journal of Receptor Research. 11: 603-25. PMID 1715922 DOI: 10.3109/10799899109066430  1
1991 Aracava Y, Fróes-Ferrão MM, Pereira EF, Albuquerque EX. Sensitivity of N-methyl-D-aspartate (NMDA) and nicotinic acetylcholine receptors to ethanol and pyrazole. Annals of the New York Academy of Sciences. 625: 451-72. PMID 1711814  1
1990 Alkondon M, Albuquerque EX. alpha-Cobratoxin blocks the nicotinic acetylcholine receptor in rat hippocampal neurons. European Journal of Pharmacology. 191: 505-6. PMID 2086254 DOI: 10.1016/0014-2999(90)94190-9  1
1990 Ramoa AS, Alkondon M, Aracava Y, Irons J, Lunt GG, Deshpande SS, Wonnacott S, Aronstam RS, Albuquerque EX. The anticonvulsant MK-801 interacts with peripheral and central nicotinic acetylcholine receptor ion channels. The Journal of Pharmacology and Experimental Therapeutics. 254: 71-82. PMID 1694895  1
1990 Kofuji P, Aracava Y, Swanson KL, Aronstam RS, Rapoport H, Albuquerque EX. Activation and blockade of the acetylcholine receptor-ion channel by the agonists (+)-anatoxin-a, the N-methyl derivative and the enantiomer. The Journal of Pharmacology and Experimental Therapeutics. 252: 517-25. PMID 1690292  1
1990 Costa AC, Swanson KL, Aracava Y, Aronstam RS, Albuquerque EX. Molecular effects of dimethylanatoxin on the peripheral nicotinic acetylcholine receptor. The Journal of Pharmacology and Experimental Therapeutics. 252: 507-16. PMID 1690291  1
1990 Alkondon M, Costa AC, Radhakrishnan V, Aronstam RS, Albuquerque EX. Selective blockade of NMDA-activated channel currents may be implicated in learning deficits caused by lead. Febs Letters. 261: 124-30. PMID 1689669 DOI: 10.1016/0014-5793(90)80652-Y  1
1989 Kawabuchi M, Boyne AF, Deshpande SS, Albuquerque EX. The reversible carbamate, (-)physostigmine, reduces the size of synaptic end plate lesions induced by sarin, an irreversible organophosphate. Toxicology and Applied Pharmacology. 97: 98-106. PMID 2916238 DOI: 10.1016/0041-008X(89)90058-6  1
1989 Rozental R, Aracava Y, Scoble GT, Swanson KL, Wonnacott S, Albuquerque EX. Agonist recognition site of the peripheral acetylcholine receptor ion channel complex differentiates the enantiomers of nicotine. The Journal of Pharmacology and Experimental Therapeutics. 251: 395-404. PMID 2478693  1
1989 Alkondon M, Albuquerque EX. The nonoxime bispyridinium compound SAD-128 alters the kinetic properties of the nicotinic acetylcholine receptor ion channel: a possible mechanism for antidotal effects. The Journal of Pharmacology and Experimental Therapeutics. 250: 842-52. PMID 2476549  1
1989 Rozental R, Scoble GT, Albuquerque EX, Idriss M, Sherby S, Sattelle DB, Nakanishi K, Konno K, Eldefrawi AT, Eldefrawi ME. Allosteric inhibition of nicotinic acetylcholine receptors of vertebrates and insects by philanthotoxin. The Journal of Pharmacology and Experimental Therapeutics. 249: 123-30. PMID 2468760  1
1989 Lima-Landman MT, Albuquerque EX. Ethanol potentiates and blocks NMDA-activated single-channel currents in rat hippocampal pyramidal cells. Febs Letters. 247: 61-7. PMID 2468533 DOI: 10.1016/0014-5793(89)81241-4  1
1989 Swanson KL, Aracava Y, Sardina FJ, Rapoport H, Aronstam RS, Albuquerque EX. N-methylanatoxinol isomers: derivatives of the agonist (+)-anatoxin-a block the nicotinic acetylcholine receptor ion channel. Molecular Pharmacology. 35: 223-31. PMID 2465486  1
1989 Albuquerque EX, Alkondon M, Lima-Landman MT, Deshpande SS, Ramoa AS. Molecular targets of noncompetitive blockers at the central and peripheral nicotinic and glutamatergic receptors Fernstrom Foundation Series. 13: 273-300.  1
1988 Kawabuchi M, Boyne AF, Deshpande SS, Cintra WM, Brossi A, Albuquerque EX. Enantiomer (+)physostigmine prevents organophosphate-induced subjunctional damage at the neuromuscular synapse by a mechanism not related to cholinesterase carbamylation. Synapse (New York, N.Y.). 2: 139-47. PMID 3420535 DOI: 10.1002/syn.890020205  1
1988 Macallan DR, Lunt GG, Wonnacott S, Swanson KL, Rapoport H, Albuquerque EX. Methyllycaconitine and (+)-anatoxin-a differentiate between nicotinic receptors in vertebrate and invertebrate nervous systems. Febs Letters. 226: 357-63. PMID 3338564 DOI: 10.1016/0014-5793(88)81454-6  1
1988 Albuquerque EX, Aracava Y, Cintra WM, Brossi A, Schönenberger B, Deshpande SS. Structure-activity relationship of reversible cholinesterase inhibitors: activation, channel blockade and stereospecificity of the nicotinic acetylcholine receptor-ion channel complex. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 21: 1173-96. PMID 3074841  1
1988 Albuquerque EX, Daly JW, Warnick JE. Macromolecular sites for specific neurotoxins and drugs on chemosensitive synapses and electrical excitation in biological membranes. Ion Channels. 1: 95-162. PMID 2485004  1
1988 Ramoa AS, Albuquerque EX. Phencyclidine and some of its analogues have distinct effects on NMDA receptors of rat hippocampal neurons. Febs Letters. 235: 156-62. PMID 2456947 DOI: 10.1016/0014-5793(88)81254-7  1
1988 Alkondon M, Rao KS, Albuquerque EX. Acetylcholinesterase reactivators modify the functional properties of the nicotinic acetylcholine receptor ion channel. The Journal of Pharmacology and Experimental Therapeutics. 245: 543-56. PMID 2452874  1
1988 Aronstam RS, Edwards MW, Daly JW, Albuquerque EX. Interactions of piperidine derivatives with the nicotinic cholinergic receptor complex from Torpedo electric organ. Neurochemical Research. 13: 171-6. PMID 2452357  0.44
1987 Oliveira L, Madsen BW, Kapai N, Sherby SM, Swanson KL, Eldefrawi ME, Albuquerque EX. Interaction of narcotic antagonist naltrexone with nicotinic acetylcholine receptor. European Journal of Pharmacology. 140: 331-42. PMID 3653249 DOI: 10.1016/0014-2999(87)90290-1  1
1987 Rao KS, Warnick JE, Daly JW, Albuquerque EX. Pharmacology of the alkaloid pumiliotoxin-B. II. Possible involvement of calcium and sodium-dependent processes in nerve and skeletal muscle. The Journal of Pharmacology and Experimental Therapeutics. 243: 775-83. PMID 3500302  1
1987 Swanson KL, Albuquerque EX. Nicotinic acetylcholine receptor ion channel blockade by cocaine: the mechanism of synaptic action. The Journal of Pharmacology and Experimental Therapeutics. 243: 1202-10. PMID 2447267  1
1987 Aguayo LG, Albuquerque EX. Phencyclidine blocks two potassium currents in spinal neurons in cell culture. Brain Research. 436: 9-17. PMID 2446718 DOI: 10.1016/0006-8993(87)91550-2  1
1987 Aracava Y, Deshpande SS, Rickett DL, Brossi A, Schönenberger B, Albuquerque EX. The molecular basis of anticholinesterase actions on nicotinic and glutamatergic synapses. Annals of the New York Academy of Sciences. 505: 226-55. PMID 2446549  1
1987 Aracava Y, Deshpande SS, Swanson KL, Rapoport H, Wonnacott S, Lunt G, Albuquerque EX. Nicotinic acetylcholine receptors in cultured neurons from the hippocampus and brain stem of the rat characterized by single channel recording. Febs Letters. 222: 63-70. PMID 2443390 DOI: 10.1016/0014-5793(87)80192-8  1
1987 Allen CN, Albuquerque EX. Conductance properties of GABA-activated chloride currents recorded from cultured hippocampal neurons. Brain Research. 410: 159-63. PMID 2438013 DOI: 10.1016/S0006-8993(87)80039-2  1
1987 Rapier C, Wonnacott S, Lunt GG, Albuquerque EX. The neurotoxin histrionicotoxin interacts with the putative ion channel of the nicotinic acetylcholine receptors in the central nervous system. Febs Letters. 212: 292-6. PMID 2434360 DOI: 10.1016/0014-5793(87)81363-7  1
1987 Rao KS, Aracava Y, Rickett DL, Albuquerque EX. Noncompetitive blockade of the nicotinic acetylcholine receptor-ion channel complex by an irreversible cholinesterase inhibitor. The Journal of Pharmacology and Experimental Therapeutics. 240: 337-44. PMID 2433427  1
1986 Deshpande SS, Viana GB, Kauffman FC, Rickett DL, Albuquerque EX. Effectiveness of physostigmine as a pretreatment drug for protection of rats from organophosphate poisoning. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 6: 566-77. PMID 3699340 DOI: 10.1093/toxsci/6.3.566  1
1986 Aguayo LG, Albuquerque EX. Blockade and recovery of the acetylcholine receptor produced by a thienyl analog of phencyclidine: influence of voltage, temperature, frequency of stimulation and conditioning pulse duration. The Journal of Pharmacology and Experimental Therapeutics. 239: 25-31. PMID 3489836  1
1986 Aguayo LG, Albuquerque EX. Effects of phencyclidine and its analogs on the end-plate current of the neuromuscular junction. The Journal of Pharmacology and Experimental Therapeutics. 239: 15-24. PMID 3489835  1
1986 Sokolove PM, Albuquerque EX, Kauffman FC, Spande TF, Daly JW. Phenolic antioxidants: potent inhibitors of the (Ca2+ + Mg2+)-ATPase of sarcoplasmic reticulum. Febs Letters. 203: 121-6. PMID 2942419 DOI: 10.1016/0014-5793(86)80726-8  1
1986 Idriss MK, Aguayo LG, Rickett DL, Albuquerque EX. Organophosphate and carbamate compounds have pre- and postjunctional effects at the insect glutamatergic synapse. The Journal of Pharmacology and Experimental Therapeutics. 239: 279-85. PMID 2876093  1
1986 Aronstam RS, Daly JW, Spande TF, Narayanan TK, Albuquerque EX. Interaction of gephyrotoxin and indolizidine alkaloids with the nicotinic acetylcholine receptor-ion channel complex of Torpedo electroplax. Neurochemical Research. 11: 1227-40. PMID 2431336 DOI: 10.1007/BF00965950  1
1986 Aguayo LG, Witkop B, Albuquerque EX. Voltage- and time-dependent effects of phencyclidines on the endplate current arise from open and closed channel blockade. Proceedings of the National Academy of Sciences of the United States of America. 83: 3523-7. PMID 2422653  1
1986 Albuquerque EX, Deshpande SS, Aracava Y, Alkondon M, Daly JW. A possible involvement of cyclic AMP in the expression of desensitization of the nicotinic acetylcholine receptor. A study with forskolin and its analogs. Febs Letters. 199: 113-20. PMID 2420646 DOI: 10.1016/0014-5793(86)81235-2  1
1986 Swanson KL, Allen CN, Aronstam RS, Rapoport H, Albuquerque EX. Molecular mechanisms of the potent and stereospecific nicotinic receptor agonist (+)-anatoxin-a. Molecular Pharmacology. 29: 250-7. PMID 2419745  1
1986 Allen CN, Albuquerque EX. Characteristics of acetylcholine-activated channels of innervated and chronically denervated skeletal muscles. Experimental Neurology. 91: 532-45. PMID 2419153 DOI: 10.1016/0014-4886(86)90050-6  1
1986 Sherby SM, Eldefrawi AT, Deshpande SS, Albuquerque EX, Eldefrawi ME. Effects of pyrethroids on nicotinic acetylcholine receptor binding and function Pesticide Biochemistry and Physiology. 26: 107-115. DOI: 10.1016/0048-3575(86)90082-9  1
1985 Meshul CK, Boyne AF, Deshpande SS, Albuquerque EX. Comparison of the ultrastructural myopathy induced by anticholinesterase agents at the end plates of rat soleus and extensor muscles. Experimental Neurology. 89: 96-114. PMID 4007120 DOI: 10.1016/0014-4886(85)90268-7  1
1985 Sherby SM, Eldefrawi AT, Albuquerque EX, Eldefrawi ME. Comparison of the actions of carbamate anticholinesterases on the nicotinic acetylcholine receptor. Molecular Pharmacology. 27: 343-8. PMID 3974572  1
1985 Albuquerque EX, Deshpande SS, Kawabuchi M, Aracava Y, Idriss M, Rickett DL, Boyne AF. Multiple actions of anticholinesterase agents on chemosensitive synapses: molecular basis for prophylaxis and treatment of organophosphate poisoning. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 5: S182-203. PMID 2868960 DOI: 10.1016/0272-0590(85)90129-0  1
1985 Idriss M, Albuquerque EX. Phencyclidine (PCP) blocks glutamate-activated postsynaptic currents. Febs Letters. 189: 150-6. PMID 2863172 DOI: 10.1016/0014-5793(85)80861-9  1
1985 Madsen BW, Albuquerque EX. The narcotic antagonist naltrexone has a biphasic effect on the nicotinic acetylcholine receptor. Febs Letters. 182: 20-4. PMID 2578990 DOI: 10.1016/0014-5793(85)81145-5  1
1985 Spivak CE, Albuquerque EX. Triphenylmethylphosphonium blocks the nicotinic acetylcholine receptor noncompetitively. Molecular Pharmacology. 27: 246-55. PMID 2578604  1
1985 Shaw KP, Aracava Y, Akaike A, Daly JW, Rickett DL, Albuquerque EX. The reversible cholinesterase inhibitor physostigmine has channel-blocking and agonist effects on the acetylcholine receptor-ion channel complex. Molecular Pharmacology. 28: 527-38. PMID 2417099  1
1985 Aronstam RS, King CT, Albuquerque EX, Daly JW, Feigl DM. Binding of [3H]perhydrohistrionicotoxin and [3H]phencyclidine to the nicotinic receptor-ion channel complex of Torpedo electroplax. Inhibition by histrionicotoxins and derivatives. Biochemical Pharmacology. 34: 3037-47. PMID 2412560 DOI: 10.1016/0006-2952(85)90145-5  1
1985 Varanda WA, Aracava Y, Sherby SM, VanMeter WG, Eldefrawi ME, Albuquerque EX. The acetylcholine receptor of the neuromuscular junction recognizes mecamylamine as a noncompetitive antagonist. Molecular Pharmacology. 28: 128-37. PMID 2410768  1
1984 Souccar C, Varanda WA, Aronstam RS, Daly JW, Albuquerque EX. Interactions of gephyrotoxin with the acetylcholine receptor-ionic channel complex. II. Enhancement of desensitization. Molecular Pharmacology. 25: 395-400. PMID 6328265  1
1984 Souccar C, Varanda WA, Daly JW, Albuquerque EX. Interactions of gephyrotoxin with the acetylcholine receptor-ionic channel complex. I. Blockade of the ionic channel. Molecular Pharmacology. 25: 384-94. PMID 6328264  1
1984 El-Fakahany EE, Eldefrawi AT, Murphy DL, Aguayo LG, Triggle DJ, Albuquerque EX, Eldefrawi ME. Interactions of phencyclidine with crayfish muscle membranes. Sensitivity to calcium channel antagonists and other drugs. Molecular Pharmacology. 25: 369-78. PMID 6328263  0.44
1984 Albuquerque EX, Akaike A, Shaw KP, Rickett DL. The interaction of anticholinesterase agents with the acetylcholine receptor-ionic channel complex. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 4: S27-33. PMID 6327444 DOI: 10.1016/0272-0590(84)90135-0  1
1984 Pascuzzo GJ, Akaike A, Maleque MA, Shaw KP, Aronstam RS, Rickett DL, Albuquerque EX. The nature of the interactions of pyridostigmine with the nicotinic acetylcholine receptor-ionic channel complex. I. Agonist, desensitizing, and binding properties. Molecular Pharmacology. 25: 92-101. PMID 6323955  1
1984 Akaike A, Ikeda SR, Brookes N, Pascuzzo GJ, Rickett DL, Albuquerque EX. The nature of the interactions of pyridostigmine with the nicotinic acetylcholine receptor-ionic channel complex. II. Patch clamp studies. Molecular Pharmacology. 25: 102-12. PMID 6323946  1
1984 Maleque MA, Brossi A, Witkop B, Godleski SA, Albuquerque EX. Interaction of analogs of histrionicotoxin with the acetylcholine receptor ionic channel complex and membrane excitability. The Journal of Pharmacology and Experimental Therapeutics. 229: 72-9. PMID 6323691  1
1984 Aguayo LG, Weinstein H, Maayani S, Glick SD, Warnick JE, Albuquerque EX. Discriminant effects of behaviorally active and inactive analogs of phencyclidine on membrane electrical excitability. The Journal of Pharmacology and Experimental Therapeutics. 228: 80-7. PMID 6319672  1
1984 Warnick JE, Maleque MA, Albuquerque EX. Interaction of bicyclo-octane analogs of amantadine with ionic channels of the nicotinic acetylcholine receptor and electrically excitable membrane. The Journal of Pharmacology and Experimental Therapeutics. 228: 73-9. PMID 6319671  0.44
1984 Hudson CS, Deshpande SS, Albuquerque EX. Consequences of axonal transport blockade by batrachotoxin on mammalian neuromuscular junction. III. An ultrastructural study. Brain Research. 296: 319-32. PMID 6200188 DOI: 10.1016/0006-8993(84)90068-4  1
1984 Allen CN, Akaike A, Albuquerque EX. The frog interosseal muscle fiber as a new model for patch clamp studies of chemosensitive- and voltage-sensitive ion channels: actions of acetylcholine and batrachotoxin. Journal De Physiologie. 79: 338-43. PMID 6099417  1
1984 Aracava Y, Ikeda SR, Daly JW, Brookes N, Albuquerque EX. Interactions of bupivacaine with ionic channels of the nicotinic receptor. Analysis of single-channel currents. Molecular Pharmacology. 26: 304-13. PMID 6090885  1
1984 Ikeda SR, Aronstam RS, Daly JW, Aracava Y, Albuquerque EX. Interactions of bupivacaine with ionic channels of the nicotinic receptor. Electrophysiological and biochemical studies. Molecular Pharmacology. 26: 293-303. PMID 6090884  1
1984 Maleque MA, Takahashi K, Witkop B, Brossi A, Albuquerque EX. A study of the novel synthetic analog (+/-)-depentylperhydrohistrionicotoxin on the nicotinic receptor-ion channel complex. The Journal of Pharmacology and Experimental Therapeutics. 230: 619-26. PMID 6088758  1
1984 Aracava Y, Albuquerque EX. Meproadifen enhances activation and desensitization of the acetylcholine receptor-ionic channel complex (AChR): single channel studies. Febs Letters. 174: 267-74. PMID 6088290 DOI: 10.1016/0014-5793(84)81171-0  1
1983 Spivak CE, Maleque MA, Takahashi K, Brossi A, Albuquerque EX. The ionic channel of the nicotinic acetylcholine receptor is unable to differentiate between the optical antipodes of perhydrohistrionicotoxin. Febs Letters. 163: 189-93. PMID 6315487  0.44
1983 Spivak CE, Waters J, Witkop B, Albuquerque EX. Potencies and channel properties induced by semirigid agonists at frog nicotinic acetylcholine receptors. Molecular Pharmacology. 23: 337-43. PMID 6300643  1
1983 Kalia M, Deshpande SS, Ducker T, Albuquerque EX. Evaluation of regeneration of nerve and reinnervation of skeletal muscle in the hibernating ground squirrel. Experimental Neurology. 81: 407-25. PMID 6192009  0.44
1983 Carp JS, Aronstam RS, Witkop B, Albuquerque EX. Electrophysiological and biochemical studies on enhancement of desensitization by phenothiazine neuroleptics. Proceedings of the National Academy of Sciences of the United States of America. 80: 310-4. PMID 6130531  1
1982 Max SR, Deshpande SS, Albuquerque EX. Neural regulation of muscle glucose 6-phosphate dehydrogenase: effect of batrachotoxin and tetrodotoxin. Journal of Neurochemistry. 38: 386-91. PMID 7108545  0.44
1982 Maleque MA, Souccar C, Cohen JB, Albuquerque EX. Meproadifen reaction with the ionic channel of the acetylcholine receptor: potentiation of agonist-induced desensitization at the frog neuromuscular junction. Molecular Pharmacology. 22: 636-47. PMID 6296656  1
1982 Takahashi K, Jacobson AE, Mak CP, Witkop B, Brossi A, Albuquerque EX, Warnick JE, Maleque MA, Bavoso A, Silverton JV. (+/-)-2-Depentylperhydrohistrionicotoxin: a new probe for a regulatory site on the nicotinic acetylcholine receptor-channel. Journal of Medicinal Chemistry. 25: 919-25. PMID 6288946  1
1982 Aguayo LG, Warnick JE, Maayani S, Glick SD, Weinstein H, Albuquerque EX. Site of action of phencyclidine. IV. Interaction of phencyclidine and its analogues on ionic channels of the electrically excitable membrane and nicotinic receptor: implications for behavioral effects. Molecular Pharmacology. 21: 637-47. PMID 6287200  1
1982 Spivak CE, Maleque MA, Oliveira AC, Masukawa LM, Tokuyama T, Daly JW, Albuquerque EX. Actions of the histrionicotoxins at the ion channel of the nicotinic acetylcholine receptor and at the voltage-sensitive ion channels of muscle membranes. Molecular Pharmacology. 21: 351-61. PMID 6285171  1
1982 Shaker N, Eldefrawi AT, Aguayo LG, Warnick JE, Albuquerque EX, Eldefrawi ME. Interactions of d-tubocurarine with the nicotinic acetylcholine receptor/channel molecule. The Journal of Pharmacology and Experimental Therapeutics. 220: 172-7. PMID 6273528  1
1982 Warnick JE, Jessup PJ, Overman LE, Eldefrawi ME, Nimit Y, Daly JW, Albuquerque EX. Pumiliotoxin-C and synthetic analogues. A new class of nicotinic antagonists. Molecular Pharmacology. 22: 565-73. PMID 6130469  1
1982 Deshpande SS, Hall-Craggs EC, Albuquerque EX. Electrophysiological and morphological investigation of bupivacaine-induced myopathy and terminal sprouting in the rat. Experimental Neurology. 78: 740-64. PMID 6129157  0.44
1982 Warnick JE, Maleque MA, Bakry N, Eldefrawi AT, Albuquerque EX. Structure-activity relationships of amantadine. I. Interaction of the N-alkyl analogues with the ionic channels of the nicotinic acetylcholine receptor and electrically excitable membrane. Molecular Pharmacology. 22: 82-93. PMID 6126806  1
1981 Guth L, Barrett CP, Donati EJ, Deshpande SS, Albuquerque EX. Histopathological reactions an axonal regeneration in the transected spinal cord of Hibernating squirrels. The Journal of Comparative Neurology. 203: 297-308. PMID 7309924 DOI: 10.1002/cne.902030209  0.44
1981 Eldefrawi ME, Shaker N, Mansour NA, Warnick JE, Albuquerque EX. Detection of nicotinic cholinergic transmission in Malapterurus electricus electroplax. Life Sciences. 29: 1033-7. PMID 7289769 DOI: 10.1016/0024-3205(81)90463-X  1
1981 Rash JE, Hudson CS, Graham WF, Mayer RF, Warnick JE, Albuquerque EX. Freeze fracture studies of human neuromuscular junctions. Membrane alterations observed in myasthenia gravis. Laboratory Investigation; a Journal of Technical Methods and Pathology. 44: 519-30. PMID 7230737  1
1981 Aronstam RS, Eldefrawi AT, Pessah IN, Daly JW, Albuquerque EX, Eldefrawi ME. Regulation of [3H]perhydrohistrionicotoxin binding to Torpedo ocellata electroplax by effectors of the acetylcholine receptor. The Journal of Biological Chemistry. 256: 2843-50. PMID 7204378  0.44
1981 Maleque MA, Warnick JE, Albuquerque EX. The mechanism and site of action of ketamine on skeletal muscle. The Journal of Pharmacology and Experimental Therapeutics. 219: 638-45. PMID 6975368  0.44
1981 Rash JE, Hudson CS, Albuquerque EX, Eldefrawi ME, Mayer RF, Graham WF, Johnson TJ, Giddings FD. Freeze-fracture, labelled-replica, and electrophysiological studies of junctional fold destruction in myasthenia gravis and experimental autoimmune myasthenia gravis. Annals of the New York Academy of Sciences. 377: 38-60. PMID 6951483  1
1981 Tamburini R, Albuquerque EX, Daly JW, Kauffman FC. Inhibition of calcium-dependent ATPase from sarcoplasmic reticulum by a new class of indolizidine alkaloids, pumiliotoxins A, B, and 251D. Journal of Neurochemistry. 37: 775-80. PMID 6456330  1
1981 Albuquerque EX, Warnick JE, Maleque MA, Kauffman FC, Tamburini R, Nimit Y, Daly JW. The pharmacology of pumiliotoxin-B. I. Interaction with calcium sites in the sarcoplasmic reticulum of skeletal muscle. Molecular Pharmacology. 19: 411-24. PMID 6455594  1
1981 Brown GB, Tieszen SC, Daly JW, Warnick JE, Albuquerque EX. Batrachotoxinin-A 20-alpha-benzoate: a new radioactive ligand for voltage sensitive sodium channels. Cellular and Molecular Neurobiology. 1: 19-40. PMID 6286124  0.32
1981 Albuquerque EX, Warnick JE, Mayer RF, Eldefrawi AT, Eldefrawi ME. Recent advances in the molecular mechanisms of human and animal models of myasthenia gravis. Annals of the New York Academy of Sciences. 377: 496-518. PMID 6280564  0.6
1981 Albuquerque EX, Aguayo LG, Warnick JE, Weinstein H, Glick SD, Maayani S, Ickowicz RK, Blaustein MP. The behavioral effects of phencyclidines may be due to their blockade of potassium channels. Proceedings of the National Academy of Sciences of the United States of America. 78: 7792-6. PMID 6278489  1
1981 Schofield GG, Witkop B, Warnick JE, Albuquerque EX. Differentiation of the open and closed states of the ionic channels of nicotinic acetylcholine receptors by tricyclic antidepressants. Proceedings of the National Academy of Sciences of the United States of America. 78: 5240-4. PMID 6272297  1
1981 Aguayo LG, Pazhenchevsky B, Daly JW, Albuquerque EX. The ionic channel of the acetylcholine receptor. Regulation by sites outside and inside the cell membrane which are sensitive to quaternary ligands. Molecular Pharmacology. 20: 345-55. PMID 6272092  0.32
1981 Matthews JC, Warnick JE, Albuquerque EX, Eldefrawi ME. Characterization of the electrogenic sodium channel from rat brain membranes using neurotoxin-dependent 22Na uptake. Membrane Biochemistry. 4: 71-104. PMID 6272058 DOI: 10.3109/09687688109065424  1
1981 Eldefrawi ME, Warnick JE, Schofield GG, Albuquerque EX, Eldefrawi AT. Interaction of imipramine with the ionic channel of the acetylcholine receptor of motor endplate and electric organ. Biochemical Pharmacology. 30: 1391-4. PMID 6268097 DOI: 10.1016/0006-2952(81)90331-2  1
1981 Deshpande SS, Boegman RJ, Albuquerque EX. Consequences of axonal transport blockade by batrachotoxin on mammalian neuromuscular junction. II. Late pre- and postsynaptic changes. Brain Research. 225: 115-29. PMID 6170390  0.44
1980 Aronstam RS, Eldefrawi ME, Eldefrawi AT, Albuquerque EX, Jim KF, Triggle DJ. Sites of action of phencyclidine. III. Interactions with muscarinic receptors. Molecular Pharmacology. 18: 179-84. PMID 7421791  1
1980 Deshpande SS, Warnick JE, Guth L, Albuquerque EX. Quantal release of acetylcholine does not regulate the resting membrane potential of mammalian skeletal muscle: evidence from in vivo experiments. Experimental Neurology. 70: 122-37. PMID 7418764  1
1980 Guth L, Richman E, Barrett C, Warnick JE, Albuquerque EX. The mechanism by which degenerating peripheral nerve produces extrajunctional acetylcholine sensitivity in mammalian skeletal muscle. Experimental Neurology. 68: 465-76. PMID 7379892 DOI: 10.1016/0014-4886(80)90101-6  1
1980 Guth L, Albuquerque EX, Deshpande SS, Barrett CP, Donati EJ, Warnick JE. Ineffectiveness of enzyme therapy on regeneration in the transected spinal cord of the rat. Journal of Neurosurgery. 52: 73-86. PMID 7350283 DOI: 10.3171/jns.1980.52.1.0073  0.44
1980 Spivak CE, Witkop B, Albuquerque EX. Anatoxin-a: a novel, potent agonist at the nicotinic receptor. Molecular Pharmacology. 18: 384-94. PMID 6970328  1
1980 Tsai MC, Albuquerque EX, Aronstam RS, Eldefrawi AT, Eldefrawi ME, Triggle DJ. Sites of action of phencyclidine. I. Effects on the electrical excitability and chemosensitive properties of the neuromuscular junction of skeletal muscle. Molecular Pharmacology. 18: 159-66. PMID 6968397  1
1980 Albuquerque EX, Tsai MC, Aronstam RS, Witkop B, Eldefrawi AT, Eldefrawi ME. Phencyclidine interactions with the ionic channel of the acetylcholine receptor and electrogenic membrane. Proceedings of the National Academy of Sciences of the United States of America. 77: 1224-8. PMID 6928673  1
1980 Eldefrawi ME, Eldefrawi AT, Aronstam RS, Maleque MA, Warnick JE, Albuquerque EX. [3H]Phencyclidine: a probe for the ionic channel of the nicotinic receptor. Proceedings of the National Academy of Sciences of the United States of America. 77: 7458-62. PMID 6261260  0.44
1980 Albuquerque EX, Tsai MC, Aronstam RS, Eldefrawi AT, Eldefrawi ME. Sites of action of phencyclidine. II. Interaction with the ionic channel of the nicotinic receptor. Molecular Pharmacology. 18: 167-78. PMID 6252436  1
1980 Eldefrawi AT, Bakry NM, Eldefrawi ME, Tsai MC, Albuquerque EX. Nereistoxin interaction with the acetylcholine receptor-ionic channel complex. Molecular Pharmacology. 17: 172-9. PMID 6248754  1
1980 Daly JW, Myers CW, Warnick JE, Albuquerque EX. Levels of batrachotoxin and lack of sensitivity to its action in poison-dart frogs (Phyllobates). Science (New York, N.Y.). 208: 1383-5. PMID 6246586  1
1980 Eldefrawi ME, Aronstam RS, Bakry NM, Eldefrawi AT, Albuquerque EX. Activation, inactivation, and desensitization of acetylcholine receptor channel complex detected by binding of perhydrohistrionicotoxin. Proceedings of the National Academy of Sciences of the United States of America. 77: 2309-13. PMID 6246539  1
1980 Albuquerque EX, Warnick JE, Guth L. Spinal cord regeneration and paraplegia. Progress in Clinical and Biological Research. 39: 41-62. PMID 6157162  1
1980 Boegman RJ, Deshpande SS, Albuquerque EX. Consequences of axonal transport blockade induced by batrachotoxin on mammalian neuromuscular junction I. Early pre- and postsynaptic changes. Brain Research. 187: 183-96. PMID 6153559  0.44
1980 Guth L, Smith S, Donati EJ, Albuquerque EX. Induction of intramuscular collateral nerve sprouting by neurally applied colchicine. Experimental Neurology. 67: 513-23. PMID 6153364 DOI: 10.1016/0014-4886(80)90123-5  1
1979 Matthews JC, Albuquerque EX, Eldefrawi ME. Influence of batrachotoxin, veratridine, grayanotoxin 1 and tetrodotoxin on uptake of Na-22 by rat brain membrane preparations. Life Sciences. 25: 1651-8. PMID 513972 DOI: 10.1016/0024-3205(79)90406-5  1
1979 Adler M, Oliveira AC, Albuquerque EX, Mansour NA, Eldefrawi AT. Reaction of tetraethylammonium with the open and closed conformations of the acetylcholine receptor ionic channel complex. The Journal of General Physiology. 74: 129-52. PMID 486241 DOI: 10.1085/jgp.74.1.129  1
1979 Albuquerque EX, Gage PW, Oliveira AC. Differential effect of perhydrohistrionicotoxin on 'intrinsic' and 'extrinsic' end-plate responses. The Journal of Physiology. 297: 423-42. PMID 317106  1
1979 Tiedt TN, Albuquerque EX, Bakry NM, Eldefrawi ME, Eldefrawi AT. Voltage- and time-dependent actions of piperocaine on the ion channel of the acetylcholine receptor. Molecular Pharmacology. 16: 909-21. PMID 316855  1
1979 Tsai MC, Oliveira AC, Albuquerque EX, Eldefrawi ME, Eldefrawi AT. Mode of action of quinacrine on the acetylcholine receptor ionic channel complex. Molecular Pharmacology. 16: 382-92. PMID 316101  1
1979 Adler M, Oliveira AC, Eldefrawi ME, Eldefrawi AT, Albuquerque EX. Tetraethylammonium: voltage-dependent action on endplate conductance and inhibition of ligand binding to postsynaptic proteins. Proceedings of the National Academy of Sciences of the United States of America. 76: 531-5. PMID 284372  1
1979 Albuquerque EX, Eldefrawi AT, Oliveira AC, Copio DS, Eldefrawi ME. Myasthenia gravis animal model: quantitative analysis of the efficiency of pre- and postjunctional regions of intercostal muscles in rabbits immunized with Torpedo acetylcholine receptor. Experimental Neurology. 66: 109-22. PMID 225189 DOI: 10.1016/0014-4886(79)90067-0  1
1979 Mano Y, Mano K, Mayer RF, Deshpande SS, Albuquerque EX. Effects of paraplegia produced by intrathecal 6-aminonicotinamide on motor units in the rat. Experimental Neurology. 65: 435-56. PMID 157879 DOI: 10.1016/0014-4886(79)90110-9  0.44
1978 Sarvey JM, Albuquerque EX, Eldefrawi AT, Eldefrawi M. Effects of alpha-bungarotoxin and reversible cholinergic ligands on normal and denervated mammalian skeletal muscle. Membrane Biochemistry. 1: 131-57. PMID 756485 DOI: 10.3109/09687687809064163  1
1978 Kauffman FC, Deshpande SS, Albuquerque EX. Biochemical alterations in denervated skeletal muscle and transected sciatic nerve in the hibernating ground squirrel. Experimental Neurology. 62: 335-46. PMID 729681 DOI: 10.1016/0014-4886(78)90060-2  1
1978 Eldefrawi ME, Eldefrawi AT, Mansour NA, Daly JW, Witkop B, Albuquerque EX. Acetylcholine receptor and ionic channel of Torpedo electroplax: binding of perhydrohistrionicotoxin to membrane and solubilized preparations. Biochemistry. 17: 5474-84. PMID 728410  0.68
1978 Hudson CS, Rash JE, Tiedt TN, Albuquerque EX. Neostigmine-induced alterations at the mammalian neuromuscular junction. II. Ultrastructure. The Journal of Pharmacology and Experimental Therapeutics. 205: 340-56. PMID 641832  1
1978 Garcia JH, Deshpande SS, Pence RS, Albuquerque EX. Spinal myelopathy induced by subarachnoid batrachotoxin: ultrastructure and electrophysiology. Brain Research. 140: 75-87. PMID 626887 DOI: 10.1016/0006-8993(78)90239-1  1
1978 Albuquerque EX, Eldefrawi AT, Eldefrawi ME, Mansour NA, Tsai MC. Amantadine: neuromuscular blockade by suppression of ionic conductance of the acetylcholine receptor. Science (New York, N.Y.). 199: 788-90. PMID 622570  1
1978 Masukawa LM, Albuquerque EX. Voltage- and time-dependent action of histrionicotoxin on the endplate current of the frog muscle. The Journal of General Physiology. 72: 351-67. PMID 308995  1
1978 Garrison DL, Albuquerque EX, Warnick JE, Daly JW, Witkop B. Antagonism of carbamylcholine-induced depolarization by batrachotoxin and veratridine. Molecular Pharmacology. 14: 111-21. PMID 304959  1
1978 Guth L, Albuquerque EX. The neurotrophic regulation of resting membrane potential and extrajunctional acetylcholine sensitivity in mammalian skeletal muscle. Physiologia Bohemoslovaca. 27: 401-14. PMID 216042  1
1978 Albuquerque EX, Deshpande SS, Guth L. Physiological properties of the innervated and denervated neuromuscular junction of hibernating and nonhibernating ground squirrels. Experimental Neurology. 62: 347-73. PMID 215439 DOI: 10.1016/0014-4886(78)90061-4  1
1978 Tsai MC, Mansour NA, Eldefrawi AT, Eldefrawi ME, Albuquerque EX. Mechanism of action of amantadine on neuromuscular transmission. Molecular Pharmacology. 14: 787-803. PMID 213703  1
1978 Albuquerque EX, Gage PW. Differential effects of perhydrohistrionicotoxin on neurally and iontophoretically evoked endplate currents. Proceedings of the National Academy of Sciences of the United States of America. 75: 1596-9. PMID 206910  1
1978 Tiedt TN, Albuquerque EX, Hudson CS, Rash JE. Neostigmine-induced alterations at the mammalian neuromuscular junction. I. Muscle contraction and electrophysiology. The Journal of Pharmacology and Experimental Therapeutics. 205: 326-39. PMID 205647  1
1978 Deshpande SS, Albuquerque EX, Kauffman FC, Guth L. Physiological, biochemical and histological changes in skeletal muscle, neuromuscular junction and spinal cord of rats rendered paraplegic by subarachnoidal administration of 6-aminonicotinamide. Brain Research. 140: 89-109. PMID 146536 DOI: 10.1016/0006-8993(78)90240-8  1
1977 Tiedt TN, Albuquerque EX, Guth L. Degenerating nerve fiber products do not alter physiological properties of adjacent innervated skeletal muscle fibers. Science (New York, N.Y.). 198: 839-41. PMID 918666  1
1977 Dolly JO, Albuquerque EX, Sarvey J, Mallick B, Barnard EA. Binding of perhydro-histrionicotoxin to the postsynaptic membrane of skeletal muscle in relation to its blockage of acetylcholine-induced depolarization. Molecular Pharmacology. 13: 1-14. PMID 834179  1
1977 Mayer RF, Albuquerque EX, Rash JE, Hudson CS. Neuromusclar junction and myasthenic crisis. Transactions of the American Neurological Association. 102: 100-4. PMID 616082  1
1977 Eldefrawi AT, Eldefrawi ME, Albuquerque EX, Oliveira AC, Mansour N, Adler M, Daly JW, Brown GB, Burgermeister W, Witkop B. Perhydrohistrionicotoxin: a potential ligand for the ion conductance modulator of the acetylcholine receptor. Proceedings of the National Academy of Sciences of the United States of America. 74: 2172-6. PMID 301278  1
1977 Max SR, Deshpande SS, Albuquerque EX. Neural regulation of muscle acetylcholinsterase: effects of batrachotoxin and 6-aminonicotinamide. Brain Research. 130: 101-7. PMID 141969  0.44
1977 Warnick JE, Albuquerque EX, Guth L. The demonstration of neurotrophic function by application of colchicine or vinblastine to the peripheral nerve. Experimental Neurology. 57: 622-36. PMID 20317 DOI: 10.1016/0014-4886(77)90094-2  1
1976 Albuquerque EX, Brookes N, Onur R, Warnick JE. Kinetics of interaction of batrachotoxin and tetrodotoxin on rat diaphragm muscle. Molecular Pharmacology. 12: 82-91. PMID 1256446  0.48
1976 Shotzberger GS, Albuquerque EX, Daly JW. The effects of batrachotoxin on cat papillary muscle. The Journal of Pharmacology and Experimental Therapeutics. 196: 433-44. PMID 1255486  0.32
1976 Kauffman FC, Albuquerque EX, Warnick JE, Max SR. Effect of vinblastine on neural regulation of metabolism in rat skeletal muscle. Experimental Neurology. 50: 60-6. PMID 1248546 DOI: 10.1016/0014-4886(76)90235-1  1
1976 Rash JE, Albuquerque EX, Hudson CS, Mayer RF, Satterfield JR. Studies of human myasthenia gravis: electrophysiological and ultrastructural evidence compatible with antibody attachment to acetylcholine receptor complex. Proceedings of the National Academy of Sciences of the United States of America. 73: 4584-8. PMID 1070009 DOI: 10.1073/pnas.73.12.4584  1
1976 Albuquerque EX, Lebeda FJ, Appel SH, Almon R, Kauffman FC, Mayer RF, Narahashi T, Yeh JZ. Effects of normal and myasthenic serum factors on innervated and chronically denervated mammalian muscles. Annals of the New York Academy of Sciences. 274: 475-92. PMID 1066995  1
1976 Deshpande SS, Albuquerque EX, Guth L. Neurotrophic regulation of prejunctional and postjunctional membrane at the mammalian motor endplate. Experimental Neurology. 53: 151-65. PMID 964335 DOI: 10.1016/0014-4886(76)90289-2  1
1976 Albuquerque EX, Rash JE, Mayer RF, Satterfield JR. An electrophysiological and morphological study of the neuromuscular junction in patients with myasthenia gravis. Experimental Neurology. 51: 536-63. PMID 179836 DOI: 10.1016/0014-4886(76)90179-5  1
1975 McArdle JJ, Albuquerque EX. Effects of ouabain on denervated and dystrophic muscles of the mouse. Experimental Neurology. 47: 353-6. PMID 1140236 DOI: 10.1016/0014-4886(75)90263-0  1
1975 Lapa AJ, Albuquerque EX, Sarvey JM, Daly J, Witkop B. Effects of histrionicotoxin on the chemosensitive and electrical properties of skeletal muscle. Experimental Neurology. 47: 558-80. PMID 1132464 DOI: 10.1016/0014-4886(75)90088-6  1
1975 Warnick JE, Albuquerque EX, Onur R, Jansson SE, Daly J, Tokuyama T, Witkop B. The pharmacology of batrachotoxin. VII. Structure-activity relationships and the effects of pH. The Journal of Pharmacology and Experimental Therapeutics. 193: 232-45. PMID 237113  1
1974 Jansson SE, Albuquerque EX, Daly J. The pharmacology of batrachotoxin. VI. Effects on the mammalian motor nerve terminal. The Journal of Pharmacology and Experimental Therapeutics. 189: 525-37. PMID 4829228  0.56
1974 Lapa AJ, Albuquerque EX, Daly J. An electrophysiological study of the effects of D-tubocurarine, atropine, and alpha-bungarotoxin on the cholinergic receptor in innervated and chronically denervated mammalian skeletal muscles. Experimental Neurology. 43: 375-98. PMID 4826975 DOI: 10.1016/0014-4886(74)90179-4  1
1974 Kauffman FC, Warnick JE, Albuquerque EX. Uptake of [3H]colchicine from silastic implants by mammalian nerves and muscles. Experimental Neurology. 44: 404-16. PMID 4621070 DOI: 10.1016/0014-4886(74)90204-0  1
1974 Albuquerque EX, Barnard EA, Porter CW, Warnick JE. The density of acetylcholine receptors and their sensitivity in the postsynaptic membrane of muscle endplates. Proceedings of the National Academy of Sciences of the United States of America. 71: 2818-22. PMID 4546945  1
1974 Albuquerque EX, Kuba K, Daly J. Effect of histrionicotoxin on the ionic conductance modulator of the cholinergic receptor: a quantitative analysis of the end-plate current. The Journal of Pharmacology and Experimental Therapeutics. 189: 513-24. PMID 4545376  0.56
1974 Chiu TH, Lapa AJ, Barnard EA, Albuquerque EX. Binding of D-tubocurarine and alpha-bungarotoxin in normal and denervated mouse muscles. Experimental Neurology. 43: 399-413. PMID 4363769 DOI: 10.1016/0014-4886(74)90180-0  1
1973 Albuquerque EX, Barnard EA, Chiu TH, Lapa AJ, Dolly JO, Jansson SE, Daly J, Witkop B. Acetylcholine receptor and ion conductance modulator sites at the murine neuromuscular junction: evidence from specific toxin reactions. Proceedings of the National Academy of Sciences of the United States of America. 70: 949-53. PMID 4351811  1
1972 Albuquerque EX, Sasa M, Sarvey JM. Batrachotoxin has no effect on the electrogenic membranes of lobster and crayfish muscles. Life Sciences. Pt. 1: Physiology and Pharmacology. 11: 357-63. PMID 4656856 DOI: 10.1016/0024-3205(72)90062-8  1
1969 Albuquerque EX, Chung SH, Ottoson D. The action of tetrodotoxin on the frog's isolated muscle spindle. Acta Physiologica Scandinavica. 75: 301-12. PMID 5790222 DOI: 10.1111/j.1748-1716.1969.tb04383.x  1
1968 Albuquerque EX, Thesleff S. A comparative study of membrane properties of innervated and chronically denervated fast and slow skeletal muscles of the rat. Acta Physiologica Scandinavica. 73: 471-80. PMID 5708174  1
1968 Albuquerque EX, Sokoll MD, Sonesson B, Thesleff S. Studies on the nature of the cholinergic receptor. European Journal of Pharmacology. 4: 40-6. PMID 5680369  1
1968 Albuquerque EX, Thesleff S. The effect of calcium on the skeletal muscle membrane after treatment with phospholipase C. Acta Physiologica Scandinavica. 72: 310-21. PMID 5659744 DOI: 10.1111/j.1748-1716.1968.tb03846.x  1
1968 Albuquerque EX, Thesleff S. Effects of phospholipase A and lysolecithin on some electrical properties of the muscle membrane. Acta Physiologica Scandinavica. 72: 248-52. PMID 5655757 DOI: 10.1111/j.1748-1716.1968.tb03852.x  1
1967 Albuquerque EX, Thesleff S. Influence of phospholipase C on some electrical properties of the skeletal muscle membrane. The Journal of Physiology. 190: 123-37. PMID 6038015 DOI: 10.1113/jphysiol.1967.sp008197  1
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