| Year |
Citation |
Score |
| 2019 |
Henschke L, Frese M, Hellmuth S, Marx A, Stemmann O, Mayer TU. Identification of Bioactive Small Molecule Inhibitors of Separase. Acs Chemical Biology. PMID 31553567 DOI: 10.1021/Acschembio.9B00661 |
0.426 |
|
| 2018 |
Heim A, Tischer T, Mayer TU. Calcineurin promotes APC/C activation at meiotic exit by acting on both XErp1 and Cdc20. Embo Reports. PMID 30373936 DOI: 10.15252/Embr.201846433 |
0.411 |
|
| 2018 |
Teusel F, Henschke L, Mayer TU. Small molecule tools in mitosis research. Methods in Cell Biology. 144: 137-155. PMID 29804666 DOI: 10.1016/Bs.Mcb.2018.03.005 |
0.398 |
|
| 2017 |
Locke J, Joseph AP, Peña A, Möckel MM, Mayer TU, Topf M, Moores CA. Structural basis of human kinesin-8 function and inhibition. Proceedings of the National Academy of Sciences of the United States of America. PMID 29078367 DOI: 10.1073/Pnas.1712169114 |
0.362 |
|
| 2017 |
Möckel MM, Heim A, Tischer T, Mayer TU. Xenopus laevis Kif18A is a highly processive kinesin required for meiotic spindle integrity. Biology Open. PMID 28228376 DOI: 10.1242/Bio.023952 |
0.416 |
|
| 2017 |
Heim A, Rymarczyk B, Malhotra S, Mayer TU. Regulation of Cell Division. Advances in Experimental Medicine and Biology. 953: 83-116. PMID 27975271 DOI: 10.1007/978-3-319-46095-6_3 |
0.399 |
|
| 2016 |
Möckel MM, Hund C, Mayer TU. Chemical Genetics Approach to Engineer Kinesins with Sensitivity towards a Small Molecule Inhibitor of Eg5. Chembiochem : a European Journal of Chemical Biology. PMID 27550380 DOI: 10.1002/Cbic.201600451 |
0.375 |
|
| 2016 |
Al-Obaidi N, Kastl J, Mayer TU. Small Molecule Approach to Study the Function of Mitotic Kinesins. Methods in Molecular Biology (Clifton, N.J.). 1413: 283-99. PMID 27193856 DOI: 10.1007/978-1-4939-3542-0_18 |
0.455 |
|
| 2016 |
Malhotra S, Vinod PK, Mansfeld J, Stemmann O, Mayer TU. Retraction Notice to: The Anaphase-Promoting Complex/Cyclosome Is Essential for Entry into Meiotic M-Phase. Developmental Cell. 37: 289. PMID 27165557 DOI: 10.1016/J.Devcel.2016.04.013 |
0.327 |
|
| 2016 |
Al-Obaidi N, Mitchison TJ, Crews CM, Mayer TU. Identification of MAC1: A Small Molecule That Rescues Spindle Bipolarity in Monastrol-Treated Cells. Acs Chemical Biology. PMID 27121275 DOI: 10.1021/Acschembio.6B00203 |
0.609 |
|
| 2016 |
Malhotra S, Vinod PK, Mansfeld J, Stemmann O, Mayer TU. The Anaphase-Promoting Complex/Cyclosome Is Essential for Entry into Meiotic M-Phase. Developmental Cell. 36: 94-102. PMID 26766445 DOI: 10.1016/J.Devcel.2015.12.009 |
0.424 |
|
| 2015 |
Badertscher L, Wild T, Montellese C, Alexander LT, Bammert L, Sarazova M, Stebler M, Csucs G, Mayer TU, Zamboni N, Zemp I, Horvath P, Kutay U. Genome-wide RNAi Screening Identifies Protein Modules Required for 40S Subunit Synthesis in Human Cells. Cell Reports. 13: 2879-2891. PMID 26711351 DOI: 10.1016/J.Celrep.2015.11.061 |
0.358 |
|
| 2015 |
Heim A, Konietzny A, Mayer TU. Protein phosphatase 1 is essential for Greatwall inactivation at mitotic exit. Embo Reports. 16: 1501-10. PMID 26396231 DOI: 10.15252/Embr.201540876 |
0.391 |
|
| 2015 |
Kastl J, Braun J, Prestel A, Möller HM, Huhn T, Mayer TU. Mad2 Inhibitor-1 (M2I-1): A Small Molecule Protein-Protein Interaction Inhibitor Targeting the Mitotic Spindle Assembly Checkpoint. Acs Chemical Biology. PMID 25978000 DOI: 10.1021/Acschembio.5B00121 |
0.459 |
|
| 2015 |
Braun J, Möckel MM, Strittmatter T, Marx A, Groth U, Mayer TU. Synthesis and biological evaluation of optimized inhibitors of the mitotic kinesin Kif18A. Acs Chemical Biology. 10: 554-60. PMID 25402598 DOI: 10.1021/Cb500789H |
0.442 |
|
| 2014 |
Schneider T, Schneider D, Rösner D, Malhotra S, Mortensen F, Mayer TU, Scheffner M, Marx A. Dissecting ubiquitin signaling with linkage-defined and protease resistant ubiquitin chains. Angewandte Chemie (International Ed. in English). 53: 12925-9. PMID 25196034 DOI: 10.1002/Anie.201407192 |
0.306 |
|
| 2014 |
Häfner J, Mayr MI, Möckel MM, Mayer TU. Pre-anaphase chromosome oscillations are regulated by the antagonistic activities of Cdk1 and PP1 on Kif18A. Nature Communications. 5: 4397. PMID 25048371 DOI: 10.1038/Ncomms5397 |
0.316 |
|
| 2013 |
Hörmanseder E, Tischer T, Mayer TU. Modulation of cell cycle control during oocyte-to-embryo transitions. The Embo Journal. 32: 2191-203. PMID 23892458 DOI: 10.1038/Emboj.2013.164 |
0.724 |
|
| 2013 |
Vinod PK, Zhou X, Zhang T, Mayer TU, Novak B. The role of APC/C inhibitor Emi2/XErp1 in oscillatory dynamics of early embryonic cell cycles. Biophysical Chemistry. 177: 1-6. PMID 23562861 DOI: 10.1016/J.Bpc.2013.03.002 |
0.44 |
|
| 2012 |
Tischer T, Hörmanseder E, Mayer TU. The APC/C inhibitor XErp1/Emi2 is essential for Xenopus early embryonic divisions. Science (New York, N.Y.). 338: 520-4. PMID 23019610 DOI: 10.1126/Science.1228394 |
0.748 |
|
| 2012 |
Florian S, Mayer TU. The functional antagonism between Eg5 and dynein in spindle bipolarization is not compatible with a simple push-pull model. Cell Reports. 1: 408-16. PMID 22832270 DOI: 10.1016/J.Celrep.2012.03.006 |
0.405 |
|
| 2012 |
Strobelt H, Bertini E, Braun J, Deussen O, Groth U, Mayer TU, Merhof D. HiTSEE KNIME: a visualization tool for hit selection and analysis in high-throughput screening experiments for the KNIME platform. Bmc Bioinformatics. 13: S4. PMID 22607449 DOI: 10.1186/1471-2105-13-S8-S4 |
0.3 |
|
| 2011 |
Mayr MI, Storch M, Howard J, Mayer TU. A non-motor microtubule binding site is essential for the high processivity and mitotic function of kinesin-8 Kif18A. Plos One. 6: e27471. PMID 22102900 DOI: 10.1371/Journal.Pone.0027471 |
0.355 |
|
| 2011 |
Florian S, Mayer TU. Modulated microtubule dynamics enable Hklp2/Kif15 to assemble bipolar spindles. Cell Cycle (Georgetown, Tex.). 10: 3533-44. PMID 22024925 DOI: 10.4161/Cc.10.20.17817 |
0.403 |
|
| 2011 |
Benz A, Singh V, Mayer TU, Hartig JS. Identification of novel quadruplex ligands from small molecule libraries by FRET-based high-throughput screening. Chembiochem : a European Journal of Chemical Biology. 12: 1422-6. PMID 21618675 DOI: 10.1002/Cbic.201100094 |
0.307 |
|
| 2011 |
Sironi L, Solon J, Conrad C, Mayer TU, Brunner D, Ellenberg J. Automatic quantification of microtubule dynamics enables RNAi-screening of new mitotic spindle regulators. Cytoskeleton (Hoboken, N.J.). 68: 266-78. PMID 21491614 DOI: 10.1002/Cm.20510 |
0.408 |
|
| 2011 |
Hörmanseder E, Tischer T, Heubes S, Stemmann O, Mayer TU. Non-proteolytic ubiquitylation counteracts the APC/C-inhibitory function of XErp1. Embo Reports. 12: 436-43. PMID 21399619 DOI: 10.1038/Embor.2011.32 |
0.734 |
|
| 2011 |
Strittmatter T, Bareth B, Immel TA, Huhn T, Mayer TU, Marx A. Small Molecule Inhibitors of Human DNA Polymerase λ. Acs Chemical Biology. 6: 314-9. PMID 21194240 DOI: 10.1021/Cb100382M |
0.318 |
|
| 2010 |
Svetlik J, Veizerová L, Mayer TU, Catarinella M. Monastrol analogs: a synthesis of pyrazolopyridine, benzopyranopyrazolopyridine, and oxygen-bridged azolopyrimidine derivatives and their biological screening. Bioorganic & Medicinal Chemistry Letters. 20: 4073-6. PMID 20542426 DOI: 10.1016/J.Bmcl.2010.05.085 |
0.307 |
|
| 2009 |
Catarinella M, Grüner T, Strittmatter T, Marx A, Mayer TU. BTB-1: a small molecule inhibitor of the mitotic motor protein Kif18A. Angewandte Chemie (International Ed. in English). 48: 9072-6. PMID 19856362 DOI: 10.1002/Anie.200904510 |
0.349 |
|
| 2009 |
Hümmer S, Mayer TU. Cdk1 negatively regulates midzone localization of the mitotic kinesin Mklp2 and the chromosomal passenger complex. Current Biology : Cb. 19: 607-12. PMID 19303298 DOI: 10.1016/J.Cub.2009.02.046 |
0.428 |
|
| 2007 |
Florian S, Hümmer S, Catarinella M, Mayer TU. Chemical genetics: reshaping biology through chemistry. Hfsp Journal. 1: 104-14. PMID 19404416 DOI: 10.2976/1.2752600 |
0.309 |
|
| 2007 |
Lessmann T, Leuenberger MG, Menninger S, Lopez-Canet M, Müller O, Hümmer S, Bormann J, Korn K, Fava E, Zerial M, Mayer TU, Waldmann H. Natural product-derived modulators of cell cycle progression and viral entry by enantioselective oxa Diels-Alder reactions on the solid phase. Chemistry & Biology. 14: 443-51. PMID 17462579 DOI: 10.1016/J.Chembiol.2007.02.008 |
0.372 |
|
| 2007 |
Mayr MI, Hümmer S, Bormann J, Grüner T, Adio S, Woehlke G, Mayer TU. The human kinesin Kif18A is a motile microtubule depolymerase essential for chromosome congression. Current Biology : Cb. 17: 488-98. PMID 17346968 DOI: 10.1016/J.Cub.2007.02.036 |
0.398 |
|
| 2006 |
Schust J, Sperl B, Hollis A, Mayer TU, Berg T. Stattic: a small-molecule inhibitor of STAT3 activation and dimerization. Chemistry & Biology. 13: 1235-42. PMID 17114005 DOI: 10.1016/J.Chembiol.2006.09.018 |
0.364 |
|
| 2006 |
Schmidt A, Rauh NR, Nigg EA, Mayer TU. Cytostatic factor: an activity that puts the cell cycle on hold. Journal of Cell Science. 119: 1213-8. PMID 16554437 DOI: 10.1242/Jcs.02919 |
0.413 |
|
| 2005 |
Sarli V, Huemmer S, Sunder-Plassmann N, Mayer TU, Giannis A. Synthesis and biological evaluation of novel EG5 inhibitors. Chembiochem : a European Journal of Chemical Biology. 6: 2005-13. PMID 16216042 DOI: 10.1002/Cbic.200500168 |
0.372 |
|
| 2005 |
Rauh NR, Schmidt A, Bormann J, Nigg EA, Mayer TU. Calcium triggers exit from meiosis II by targeting the APC/C inhibitor XErp1 for degradation. Nature. 437: 1048-52. PMID 16127448 DOI: 10.1038/Nature04093 |
0.379 |
|
| 2005 |
Sunder-Plassmann N, Sarli V, Gartner M, Utz M, Seiler J, Huemmer S, Mayer TU, Surrey T, Giannis A. Synthesis and biological evaluation of new tetrahydro-beta-carbolines as inhibitors of the mitotic kinesin Eg5. Bioorganic & Medicinal Chemistry. 13: 6094-111. PMID 16084101 DOI: 10.1016/J.Bmc.2005.06.027 |
0.428 |
|
| 2005 |
Schmidt A, Duncan PI, Rauh NR, Sauer G, Fry AM, Nigg EA, Mayer TU. Xenopus polo-like kinase Plx1 regulates XErp1, a novel inhibitor of APC/C activity. Genes & Development. 19: 502-13. PMID 15713843 DOI: 10.1101/Gad.320705 |
0.447 |
|
| 2005 |
Perlman ZE, Mitchison TJ, Mayer TU. High-content screening and profiling of drug activity in an automated centrosome-duplication assay. Chembiochem : a European Journal of Chemical Biology. 6: 145-51. PMID 15568197 DOI: 10.1002/Cbic.200400266 |
0.767 |
|
| 2005 |
Barun O, Kumar K, Sommer S, Langerak A, Mayer TU, Müller O, Waldmann H. Cover Picture: Natural Product-Guided Synthesis of a Spiroacetal Collection Reveals Modulators of Tubulin Cytoskeleton Integrity (Eur. J. Org. Chem. 22/2005) European Journal of Organic Chemistry. 2005: 4731-4731. DOI: 10.1002/Ejoc.200590044 |
0.315 |
|
| 2005 |
Barun O, Kumar K, Sommer S, Langerak A, Mayer TU, Müller O, Waldmann H. Natural Product-Guided Synthesis of a Spiroacetal Collection Reveals Modulators of Tubulin Cytoskeleton Integrity European Journal of Organic Chemistry. 2005: 4773-4788. DOI: 10.1002/Ejoc.200500605 |
0.319 |
|
| 2003 |
Neef R, Preisinger C, Sutcliffe J, Kopajtich R, Nigg EA, Mayer TU, Barr FA. Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis. The Journal of Cell Biology. 162: 863-75. PMID 12939256 DOI: 10.1083/Jcb.200306009 |
0.358 |
|
| 2003 |
Hotha S, Yarrow JC, Yang JG, Garrett S, Renduchintala KV, Mayer TU, Kapoor TM. HR22C16: a potent small-molecule probe for the dynamics of cell division. Angewandte Chemie (International Ed. in English). 42: 2379-82. PMID 12783501 DOI: 10.1002/Anie.200351173 |
0.729 |
|
| 2003 |
Mayer TU. Chemical genetics: tailoring tools for cell biology Trends in Cell Biology. 13: 270-277. PMID 12742171 DOI: 10.1016/S0962-8924(03)00077-1 |
0.349 |
|
| 2001 |
Haggarty SJ, Mayer TU, Miyamoto DT, Fathi R, King RW, J. Mitchison T, Schreiber SL. Erratum to ‘Dissecting cellular processes using small molecules: identification of colchicine-like, taxol-like and other small molecules that perturb mitosis’ Chemistry & Biology. 8: 1265. DOI: 10.1016/S1074-5521(01)00083-7 |
0.62 |
|
| 2000 |
Kapoor TM, Mayer TU, Coughlin ML, Mitchison TJ. Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5. The Journal of Cell Biology. 150: 975-88. PMID 10973989 DOI: 10.1083/Jcb.150.5.975 |
0.705 |
|
| 2000 |
Haggarty SJ, Mayer TU, Miyamoto DT, Fathi R, King RW, Mitchison TJ, Schreiber SL. Dissecting cellular processes using small molecules: identification of colchicine-like, taxol-like and other small molecules that perturb mitosis. Chemistry & Biology. 7: 275-86. PMID 10780927 DOI: 10.1016/S1074-5521(00)00101-0 |
0.726 |
|
| 2000 |
Tournebize R, Popov A, Kinoshita K, Ashford AJ, Rybina S, Pozniakovsky A, Mayer TU, Walczak CE, Karsenti E, Hyman AA. Control of microtubule dynamics by the antagonistic activities of XMAP215 and XKCM1 in Xenopus egg extracts. Nature Cell Biology. 2: 13-9. PMID 10620801 DOI: 10.1038/71330 |
0.685 |
|
| 1999 |
Mayer TU, Kapoor TM, Haggarty SJ, King RW, Schreiber SL, Mitchison TJ. Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen. Science (New York, N.Y.). 286: 971-4. PMID 10542155 DOI: 10.1126/Science.286.5441.971 |
0.715 |
|
| 1999 |
Koegl M, Hoppe T, Schlenker S, Ulrich HD, Mayer TU, Jentsch S. A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly. Cell. 96: 635-44. PMID 10089879 DOI: 10.1016/S0092-8674(00)80574-7 |
0.661 |
|
| 1998 |
Mayer TU, Braun T, Jentsch S. Role of the proteasome in membrane extraction of a short-lived ER-transmembrane protein. The Embo Journal. 17: 3251-7. PMID 9628862 DOI: 10.1093/Emboj/17.12.3251 |
0.518 |
|
| Show low-probability matches. |