| Year |
Citation |
Score |
| 2024 |
Perneczky R, Hansen N, Hofmann A, Laske C, Priller J, Grimmer T, Frölich L, Düzel E, Jessen F, Wiltfang J. Blood-Based Biomarkers for Early Alzheimer's Disease Diagnosis in Real-World Settings. Methods in Molecular Biology (Clifton, N.J.). 2785: 3-14. PMID 38427184 DOI: 10.1007/978-1-0716-3774-6_1 |
0.363 |
|
| 2024 |
Soares Martins T, Pelech S, Ferreira M, Pinho B, Leandro K, de Almeida LP, Breitling B, Hansen N, Esselmann H, Wiltfang J, da Cruz E Silva OAB, Henriques AG. Phosphoproteome Microarray Analysis of Extracellular Particles as a Tool to Explore Novel Biomarker Candidates for Alzheimer's Disease. International Journal of Molecular Sciences. 25. PMID 38338863 DOI: 10.3390/ijms25031584 |
0.334 |
|
| 2024 |
Morgado B, Klafki HW, Bauer C, Waniek K, Esselmann H, Wirths O, Hansen N, Lachmann I, Osterloh D, Schuchhardt J, Wiltfang J. Assessment of immunoprecipitation with subsequent immunoassays for the blood-based diagnosis of Alzheimer's disease. European Archives of Psychiatry and Clinical Neuroscience. PMID 38316685 DOI: 10.1007/s00406-023-01751-2 |
0.311 |
|
| 2024 |
Hahn L, Eickhoff SB, Mueller K, Schilbach L, Barthel H, Fassbender K, Fliessbach K, Kornhuber J, Prudlo J, Synofzik M, Wiltfang J, Diehl-Schmid J, Otto M, Dukart J, Schroeter ML. Resting-state alterations in behavioral variant frontotemporal dementia are related to the distribution of monoamine and GABA neurotransmitter systems. Elife. 13. PMID 38224473 DOI: 10.7554/eLife.86085 |
0.356 |
|
| 2024 |
Teipel SJ, Dyrba M, Kleineidam L, Brosseron F, Levin F, Bruno D, Buerger K, Cosma N, Schneider LS, Düzel E, Glanz W, Fliessbach K, Janowitz D, Kilimann I, Laske C, ... ... Wiltfang J, et al. Association of latent factors of neuroinflammation with Alzheimer's disease pathology and longitudinal cognitive decline. Alzheimer's & Dementia (Amsterdam, Netherlands). 16: e12510. PMID 38213951 DOI: 10.1002/dad2.12510 |
0.34 |
|
| 2023 |
Teipel SJ, Dyrba M, Levin F, Altenstein S, Berger M, Beyle A, Brosseron F, Buerger K, Burow L, Dobisch L, Ewers M, Fliessbach K, Frommann I, Glanz W, Goerss D, ... ... Wiltfang J, et al. Cognitive Trajectories in Preclinical and Prodromal Alzheimer's Disease Related to Amyloid Status and Brain Atrophy: A Bayesian Approach. Journal of Alzheimer's Disease Reports. 7: 1055-1076. PMID 37849637 DOI: 10.3233/ADR-230027 |
0.338 |
|
| 2023 |
Waschkies KF, Soch J, Darna M, Richter A, Altenstein S, Beyle A, Brosseron F, Buchholz F, Butryn M, Dobisch L, Ewers M, Fliessbach K, Gabelin T, Glanz W, Goerss D, ... ... Wiltfang J, et al. Machine learning-based classification of Alzheimer's disease and its at-risk states using personality traits, anxiety, and depression. International Journal of Geriatric Psychiatry. 38: e6007. PMID 37800601 DOI: 10.1002/gps.6007 |
0.307 |
|
| 2023 |
Ferreira MJC, Martins TS, Alves SR, Rosa IM, Vogelgsang J, Hansen N, Wiltfang J, da Cruz E Silva OAB, Vitorino R, Henriques AG. Bioinformatic analysis of the SPs and NFTs proteomes unravel putative biomarker candidates for Alzheimer's disease. Proteomics. e2200515. PMID 37062942 DOI: 10.1002/pmic.202200515 |
0.32 |
|
| 2023 |
Chapman CA, Polyakova M, Mueller K, Weise C, Fassbender K, Fliessbach K, Kornhuber J, Lauer M, Anderl-Straub S, Ludolph A, Prudlo J, Staiger A, Synofzik M, Wiltfang J, Riedl L, et al. Structural correlates of language processing in primary progressive aphasia. Brain Communications. 5: fcad076. PMID 37013177 DOI: 10.1093/braincomms/fcad076 |
0.305 |
|
| 2023 |
de Rojas I, Moreno-Grau S, Tesi N, Grenier-Boley B, Andrade V, Jansen IE, Pedersen NL, Stringa N, Zettergren A, Hernández I, Montrreal L, Antúnez C, Antonell A, Tankard RM, Bis JC, ... ... Wiltfang J, et al. Author Correction: Common variants in Alzheimer's disease and risk stratification by polygenic risk scores. Nature Communications. 14: 716. PMID 36759603 DOI: 10.1038/s41467-023-36192-x |
0.37 |
|
| 2023 |
Brosseron F, Maass A, Kleineidam L, Ravichandran KA, Kolbe CC, Wolfsgruber S, Santarelli F, Häsler LM, McManus R, Ising C, Röske S, Peters O, Cosma NC, Schneider LS, Wang X, ... ... Wiltfang J, et al. Serum IL-6, sAXL, and YKL-40 as systemic correlates of reduced brain structure and function in Alzheimer's disease: results from the DELCODE study. Alzheimer's Research & Therapy. 15: 13. PMID 36631909 DOI: 10.1186/s13195-022-01118-0 |
0.331 |
|
| 2023 |
Kruse C, Maier F, Spottke A, Bach JP, Bartels C, Buerger K, Fellgiebel A, Fliessbach K, Frölich L, Hausner L, Hellmich M, Klöppel S, Klostermann A, Kornhuber J, Laske C, ... ... Wiltfang J, et al. Apathy in patients with Alzheimer's disease is a cost-driving factor. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36588502 DOI: 10.1002/alz.12915 |
0.433 |
|
| 2022 |
Ersoezlue E, Rauchmann BS, Schneider-Axmann T, Wagner M, Ballarini T, Tato M, Utecht J, Kurz C, Papazov B, Guersel S, Burow L, Koller G, Stöcklein S, Keeser D, Bartels C, ... ... Wiltfang J, et al. Lifelong experiences as a proxy of cognitive reserve moderate the association between connectivity and cognition in Alzheimer's disease. Neurobiology of Aging. 122: 33-44. PMID 36476760 DOI: 10.1016/j.neurobiolaging.2022.05.015 |
0.327 |
|
| 2022 |
Klafki HW, Morgado B, Wirths O, Jahn O, Bauer C, Esselmann H, Schuchhardt J, Wiltfang J. Is plasma amyloid-β 1-42/1-40 a better biomarker for Alzheimer's disease than AβX-42/X-40? Fluids and Barriers of the Cns. 19: 96. PMID 36461122 DOI: 10.1186/s12987-022-00390-4 |
0.301 |
|
| 2022 |
Kleineidam L, Wagner M, Guski J, Wolfsgruber S, Miebach L, Bickel H, König HH, Weyerer S, Lühmann D, Kaduszkiewicz H, Luppa M, Röhr S, Pentzek M, Wiese B, Maier W, ... ... Wiltfang J, et al. Disentangling the relationship of subjective cognitive decline and depressive symptoms in the development of cognitive decline and dementia. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36218120 DOI: 10.1002/alz.12785 |
0.374 |
|
| 2022 |
Oeckl P, Anderl-Straub S, Danek A, Diehl-Schmid J, Fassbender K, Fliessbach K, Halbgebauer S, Huppertz HJ, Jahn H, Kassubek J, Kornhuber J, Landwehrmeyer B, Lauer M, Prudlo J, Schneider A, ... ... Wiltfang J, et al. Relationship of serum beta-synuclein with blood biomarkers and brain atrophy. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36129098 DOI: 10.1002/alz.12790 |
0.419 |
|
| 2022 |
Jansen IE, van der Lee SJ, Gomez-Fonseca D, de Rojas I, Dalmasso MC, Grenier-Boley B, Zettergren A, Mishra A, Ali M, Andrade V, Bellenguez C, Kleineidam L, Küçükali F, Sung YJ, Tesí N, ... ... Wiltfang J, et al. Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers. Acta Neuropathologica. PMID 36066633 DOI: 10.1007/s00401-022-02454-z |
0.513 |
|
| 2022 |
Billette OV, Ziegler G, Aruci M, Schütze H, Kizilirmak JM, Richter A, Altenstein S, Bartels C, Brosseron F, Cardenas-Blanco A, Dahmen P, Dechent P, Dobisch L, Fliessbach K, Freiesleben SD, ... ... Wiltfang J, et al. Novelty-Related fMRI Responses of Precuneus and Medial Temporal Regions in Individuals at Risk for Alzheimer Disease. Neurology. 99: e775-e788. PMID 35995589 DOI: 10.1212/WNL.0000000000200667 |
0.317 |
|
| 2022 |
Koutsouleris N, Pantelis C, Velakoulis D, McGuire P, Dwyer DB, Urquijo-Castro MF, Paul R, Dong S, Popovic D, Oeztuerk O, Kambeitz J, Salokangas RKR, Hietala J, Bertolino A, Brambilla P, ... ... Wiltfang J, et al. Exploring Links Between Psychosis and Frontotemporal Dementia Using Multimodal Machine Learning: Dementia Praecox Revisited. Jama Psychiatry. PMID 35921104 DOI: 10.1001/jamapsychiatry.2022.2075 |
0.421 |
|
| 2022 |
Onur OA, Wolff-Menzler C, von Arnim CAF, Jessen F, Fink GR, Wiltfang J, Laske C, Schneider A, Levin J, Oberstein T, Kornhuber J, Oberhauser F, Gallinat J, Dodel R, Otto M, et al. [The Cost of Early Diagnosis of Cognitive Decline in German Memory Clinics]. Fortschritte Der Neurologie-Psychiatrie. 90: 361-367. PMID 35858613 DOI: 10.1055/a-1871-9889 |
0.36 |
|
| 2022 |
Polcher A, Wolfsgruber S, Peters O, Frölich L, Wiltfang J, Kornhuber J, Hüll M, Rüther E, Lewczuk P, Maier W, Jessen F, Wagner M. A Comparison of Operational Definitions for Mild Cognitive Impairment. Journal of Alzheimer's Disease : Jad. PMID 35811516 DOI: 10.3233/JAD-215548 |
0.356 |
|
| 2022 |
Bellenguez C, Küçükali F, Jansen IE, Kleineidam L, Moreno-Grau S, Amin N, Naj AC, Campos-Martin R, Grenier-Boley B, Andrade V, Holmans PA, Boland A, Damotte V, van der Lee SJ, Costa MR, ... ... Wiltfang J, et al. New insights into the genetic etiology of Alzheimer's disease and related dementias. Nature Genetics. PMID 35379992 DOI: 10.1038/s41588-022-01024-z |
0.48 |
|
| 2022 |
Hansen N, Juhl AL, Grenzer IM, Hirschel S, Teegen B, Fitzner D, Bartels C, Timäus C, Wiltfang J, Malchow B. Cerebrospinal Fluid Total Tau Protein Correlates With Longitudinal, Progressing Cognitive Dysfunction in Anti-Neural Autoantibody-Associated Dementia and Alzheimer's Dementia: A Case-Control Study. Frontiers in Immunology. 13: 837376. PMID 35309366 DOI: 10.3389/fimmu.2022.837376 |
0.344 |
|
| 2022 |
Hermann P, Haller P, Goebel S, Bunck T, Schmidt C, Wiltfang J, Zerr I. Total and Phosphorylated Cerebrospinal Fluid Tau in the Differential Diagnosis of Sporadic Creutzfeldt-Jakob Disease and Rapidly Progressive Alzheimer's Disease. Viruses. 14. PMID 35215868 DOI: 10.3390/v14020276 |
0.313 |
|
| 2022 |
Soares Martins T, Marçalo R, da Cruz E Silva CB, Trindade D, Catita J, Amado F, Melo T, Rosa IM, Vogelgsang J, Wiltfang J, da Cruz E Silva OAB, Henriques AG. Novel Exosome Biomarker Candidates for Alzheimer's Disease Unravelled Through Mass Spectrometry Analysis. Molecular Neurobiology. 59: 2838-2854. PMID 35212939 DOI: 10.1007/s12035-022-02762-1 |
0.331 |
|
| 2022 |
Jansen WJ, Janssen O, Tijms BM, Vos SJB, Ossenkoppele R, Visser PJ, Aarsland D, Alcolea D, Altomare D, von Arnim C, Baiardi S, Baldeiras I, Barthel H, Bateman RJ, ... ... Wiltfang J, et al. Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum. Jama Neurology. PMID 35099509 DOI: 10.1001/jamaneurol.2021.5216 |
0.455 |
|
| 2022 |
Martino Adami PV, Orellana A, García P, Kleineidam L, Alarcón-Martín E, Montrreal L, Aguilera N, Espinosa A, Abdelnour C, Rosende-Roca M, Tartari JP, Vargas L, Mauleón A, Esteban-De Antonio E, López-Cuevas R, ... ... Wiltfang J, et al. Matrix metalloproteinase 10 is linked to the risk of progression to dementia of the Alzheimer's type. Brain : a Journal of Neurology. PMID 35088840 DOI: 10.1093/brain/awac024 |
0.508 |
|
| 2022 |
Benson GS, Bauer C, Hausner L, Couturier S, Lewczuk P, Peters O, Hüll M, Jahn H, Jessen F, Pantel J, Teipel SJ, Wagner M, Schuchhardt J, Wiltfang J, Kornhuber J, et al. Don't forget about tau: the effects of ApoE4 genotype on Alzheimer's disease cerebrospinal fluid biomarkers in subjects with mild cognitive impairment-data from the Dementia Competence Network. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 35061102 DOI: 10.1007/s00702-022-02461-0 |
0.517 |
|
| 2022 |
Seckin M, Ricard I, Raiser T, Heitkamp N, Ebert A, Prix C, Levin J, Diehl-Schmid J, Riedl L, Roßmeier C, Hoen N, Schroeter ML, Marschhauser A, Obrig H, Benke T, ... ... Wiltfang J, et al. Utility of the Repeat and Point Test for Subtyping Patients With Primary Progressive Aphasia. Alzheimer Disease and Associated Disorders. PMID 35001030 DOI: 10.1097/WAD.0000000000000482 |
0.323 |
|
| 2022 |
Klafki HW, Wirths O, Mollenhauer B, Liepold T, Rieper P, Esselmann H, Vogelgsang J, Wiltfang J, Jahn O. Detection and Quantification of Aβ-3-40 (APP669-711) in Cerebrospinal Fluid. Journal of Neurochemistry. PMID 34984682 DOI: 10.1111/jnc.15571 |
0.336 |
|
| 2021 |
Anderl-Straub S, Lausser L, Lombardi J, Uttner I, Fassbender K, Fliessbach K, Huppertz HJ, Jahn H, Kornhuber J, Obrig H, Schneider A, Semler E, Synofzik M, Danek A, Prudlo J, ... ... Wiltfang J, et al. Predicting disease progression in behavioral variant frontotemporal dementia. Alzheimer's & Dementia (Amsterdam, Netherlands). 13: e12262. PMID 35005196 DOI: 10.1002/dad2.12262 |
0.405 |
|
| 2021 |
Brosseron F, Maass A, Kleineidam L, Ravichandran KA, González PG, McManus RM, Ising C, Santarelli F, Kolbe CC, Häsler LM, Wolfsgruber S, Marquié M, Boada M, Orellana A, de Rojas I, ... ... Wiltfang J, et al. Soluble TAM receptors sAXL and sTyro3 predict structural and functional protection in Alzheimer's disease. Neuron. PMID 34995486 DOI: 10.1016/j.neuron.2021.12.016 |
0.344 |
|
| 2021 |
Lewczuk P, Wiltfang J, Kornhuber J, Verhasselt A. Distributions of Aβ42 and Aβ42/40 in the Cerebrospinal Fluid in View of the Probability Theory. Diagnostics (Basel, Switzerland). 11. PMID 34943609 DOI: 10.3390/diagnostics11122372 |
0.476 |
|
| 2021 |
Delaby C, Teunissen CE, Blennow K, Alcolea D, Arisi I, Amar EB, Beaume A, Bedel A, Bellomo G, Bigot-Corbel E, Bjerke M, Blanc-Quintin MC, Boada M, Bousiges O, Chapman MD, ... ... Wiltfang J, et al. Clinical reporting following the quantification of cerebrospinal fluid biomarkers in Alzheimer's disease: An international overview. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 34936194 DOI: 10.1002/alz.12545 |
0.328 |
|
| 2021 |
Teipel SJ, Dyrba M, Ballarini T, Brosseron F, Bruno D, Buerger K, Cosma NC, Dechent P, Dobisch L, Düzel E, Ewers M, Fliessbach K, Haynes JD, Janowitz D, Kilimann I, ... ... Wiltfang J, et al. Association of Cholinergic Basal Forebrain Volume and Functional Connectivity with Markers of Inflammatory Response in the Alzheimer's Disease Spectrum. Journal of Alzheimer's Disease : Jad. PMID 34924387 DOI: 10.3233/JAD-215196 |
0.316 |
|
| 2021 |
Wagner M, Lorenz G, Volk AE, Brunet T, Edbauer D, Berutti R, Zhao C, Anderl-Straub S, Bertram L, Danek A, Deschauer M, Dill V, Fassbender K, Fliessbach K, Götze KS, ... ... Wiltfang J, et al. Clinico-genetic findings in 509 frontotemporal dementia patients. Molecular Psychiatry. PMID 34561610 DOI: 10.1038/s41380-021-01271-2 |
0.384 |
|
| 2021 |
Ophey A, Wolfsgruber S, Roeske S, Polcher A, Spottke A, Frölich L, Hüll M, Jessen F, Kornhuber J, Maier W, Peters O, Ramirez A, Wiltfang J, Liepelt-Scarfone I, Becker S, et al. Cognitive profiles of patients with mild cognitive impairment due to Alzheimer's versus Parkinson's disease defined using a base rate approach: Implications for neuropsychological assessments. Alzheimer's & Dementia (Amsterdam, Netherlands). 13: e12223. PMID 34541284 DOI: 10.1002/dad2.12223 |
0.443 |
|
| 2021 |
de Rojas I, Moreno-Grau S, Tesi N, Grenier-Boley B, Andrade V, Jansen IE, Pedersen NL, Stringa N, Zettergren A, Hernández I, Montrreal L, Antúnez C, Antonell A, Tankard RM, Bis JC, ... ... Wiltfang J, et al. Common variants in Alzheimer's disease and risk stratification by polygenic risk scores. Nature Communications. 12: 3417. PMID 34099642 DOI: 10.1038/s41467-021-22491-8 |
0.433 |
|
| 2021 |
Ballarini T, Melo van Lent D, Brunner J, Schröder A, Wolfsgruber S, Altenstein S, Brosseron F, Buerger K, Dechent P, Dobisch L, Duzel E, Ertl-Wagner B, Fliessbach K, Freiesleben SD, Frommann I, ... ... Wiltfang J, et al. Mediterranean Diet, Alzheimer Disease Biomarkers and Brain Atrophy in Old Age. Neurology. PMID 33952652 DOI: 10.1212/WNL.0000000000012067 |
0.337 |
|
| 2021 |
Aichholzer F, Klafki HW, Ogorek I, Vogelgsang J, Wiltfang J, Scherbaum N, Weggen S, Wirths O. Evaluation of cerebrospinal fluid glycoprotein NMB (GPNMB) as a potential biomarker for Alzheimer's disease. Alzheimer's Research & Therapy. 13: 94. PMID 33947460 DOI: 10.1186/s13195-021-00828-1 |
0.353 |
|
| 2021 |
Soares Martins T, Marçalo R, Ferreira M, Vaz M, Silva RM, Martins Rosa I, Vogelgsang J, Wiltfang J, da Cruz E Silva OAB, Henriques AG. Exosomal Aβ-Binding Proteins Identified by "In Silico" Analysis Represent Putative Blood-Derived Biomarker Candidates for Alzheimer´s Disease. International Journal of Molecular Sciences. 22. PMID 33920336 DOI: 10.3390/ijms22083933 |
0.332 |
|
| 2021 |
Lombardi J, Mayer B, Semler E, Anderl-Straub S, Uttner I, Kassubek J, Diehl-Schmid J, Danek A, Levin J, Fassbender K, Fliessbach K, Schneider A, Huppertz HJ, Jahn H, Volk A, ... ... Wiltfang J, et al. Quantifying progression in primary progressive aphasia with structural neuroimaging. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33787063 DOI: 10.1002/alz.12323 |
0.325 |
|
| 2021 |
Wiltfang J, Esselmann H, Barnikol UB. [The Use of Artificial Intelligence in Alzheimer's Disease - Personalized Diagnostics and Therapy]. Psychiatrische Praxis. 48: S31-S36. PMID 33652485 DOI: 10.1055/a-1369-3133 |
0.334 |
|
| 2021 |
Oberstein TJ, Utz J, Spitzer P, Klafki HW, Wiltfang J, Lewczuk P, Kornhuber J, Maler JM. The Role of Cathepsin B in the Degradation of Aβ and in the Production of Aβ Peptides Starting With Ala2 in Cultured Astrocytes. Frontiers in Molecular Neuroscience. 13: 615740. PMID 33510618 DOI: 10.3389/fnmol.2020.615740 |
0.447 |
|
| 2021 |
Blazhenets G, Frings L, Ma Y, Sörensen A, Eidelberg D, Wiltfang J, Meyer PT. Validation of the Alzheimer Disease Dementia Conversion-Related Pattern as an ATN Biomarker of Neurodegeneration. Neurology. PMID 33408150 DOI: 10.1212/WNL.0000000000011521 |
0.329 |
|
| 2020 |
Herdick M, Dyrba M, Fritz HJ, Altenstein S, Ballarini T, Brosseron F, Buerger K, Can Cetindag A, Dechent P, Dobisch L, Duezel E, Ertl-Wagner B, Fliessbach K, Dawn Freiesleben S, Frommann I, ... ... Wiltfang J, et al. Multimodal MRI analysis of basal forebrain structure and function across the Alzheimer's disease spectrum. Neuroimage. Clinical. 28: 102495. PMID 33395986 DOI: 10.1016/j.nicl.2020.102495 |
0.335 |
|
| 2020 |
Bartels C, Kögel A, Schweda M, Wiltfang J, Pentzek M, Schicktanz S, Schneider A. Use of Cerebrospinal Fluid Biomarkers of Alzheimer's Disease Risk in Mild Cognitive Impairment and Subjective Cognitive Decline in Routine Clinical Care in Germany. Journal of Alzheimer's Disease : Jad. PMID 33104034 DOI: 10.3233/JAD-200794 |
0.344 |
|
| 2020 |
Sannemann L, Schild AK, Altenstein S, Bartels C, Brosseron F, Buerger K, Cosma NC, Fliessbach K, Freiesleben SD, Glanz W, Heneka MT, Janowitz D, Kilimann I, Kobeleva X, Laske C, ... ... Wiltfang J, et al. Neuropsychiatric symptoms in at-risk groups for AD dementia and their association with worry and AD biomarkers-results from the DELCODE study. Alzheimer's Research & Therapy. 12: 131. PMID 33066827 DOI: 10.1186/s13195-020-00701-7 |
0.312 |
|
| 2020 |
Klafki HW, Rieper P, Matzen A, Zampar S, Wirths O, Vogelgsang J, Osterloh D, Rohdenburg L, Oberstein TJ, Jahn O, Beyer I, Lachmann I, Knölker HJ, Wiltfang J. Development and Technical Validation of an Immunoassay for the Detection of APP (Aβ) in Biological Samples. International Journal of Molecular Sciences. 21. PMID 32911706 DOI: 10.3390/Ijms21186564 |
0.443 |
|
| 2020 |
Bartels C, Belz M, Vogelgsang J, Hessmann P, Bohlken J, Wiltfang J, Kostev K. To Be Continued? Long-Term Treatment Effects of Antidepressant Drug Classes and Individual Antidepressants on the Risk of Developing Dementia: A German Case-Control Study. The Journal of Clinical Psychiatry. 81. PMID 32857931 DOI: 10.4088/Jcp.19M13205 |
0.322 |
|
| 2020 |
Bouter C, Hansen N, Timäus C, Wiltfang J, Lange C. Case Report: The Role of Neuropsychological Assessment and Imaging Biomarkers in the Early Diagnosis of Lewy Body Dementia in a Patient With Major Depression and Prolonged Alcohol and Benzodiazepine Dependence. Frontiers in Psychiatry. 11: 684. PMID 32760301 DOI: 10.3389/Fpsyt.2020.00684 |
0.35 |
|
| 2020 |
Hansen N, Hirschel S, Stöcker W, Manig A, Falk HS, Ernst M, Vukovich R, Zerr I, Wiltfang J, Bartels C. Figural Memory Impairment in Conjunction With Neuropsychiatric Symptoms in IgLON5 Antibody-Associated Autoimmune Encephalitis. Frontiers in Psychiatry. 11: 576. PMID 32714214 DOI: 10.3389/Fpsyt.2020.00576 |
0.318 |
|
| 2020 |
Wolfsgruber S, Kleineidam L, Guski J, Polcher A, Frommann I, Roeske S, Spruth EJ, Franke C, Priller J, Kilimann I, Teipel S, Buerger K, Janowitz D, Laske C, Buchmann M, ... ... Wiltfang J, et al. Minor neuropsychological deficits in patients with subjective cognitive decline. Neurology. PMID 32636322 DOI: 10.1212/Wnl.0000000000010142 |
0.425 |
|
| 2020 |
Fuentes M, Klostermann A, Kleineidam L, Bauer C, Schuchhardt J, Maier W, Jessen F, Frölich L, Wiltfang J, Kornhuber J, Klöppel S, Schieting V, Teipel SJ, Wagner M, Peters O. Identification of a Cascade of Changes in Activities of Daily Living Preceding Short-Term Clinical Deterioration in Mild Alzheimer's Disease via Lead-Lag Analysis. Journal of Alzheimer's Disease : Jad. PMID 32597807 DOI: 10.3233/Jad-200230 |
0.523 |
|
| 2020 |
Zampar S, Klafki HW, Sritharen K, Bayer TA, Wiltfang J, Rostagno A, Ghiso J, A Miles L, Wirths O. N-terminal heterogeneity of parenchymal and vascular amyloid-β deposits in Alzheimer's disease. Neuropathology and Applied Neurobiology. PMID 32497293 DOI: 10.1111/Nan.12637 |
0.437 |
|
| 2020 |
Wesselman LMP, van Lent DM, Schröder A, van de Rest O, Peters O, Menne F, Fuentes M, Priller J, Spruth EJ, Altenstein S, Schneider A, Fließbach K, Roeske S, Wolfsgruber S, Kleineidam L, ... ... Wiltfang J, et al. Dietary patterns are related to cognitive functioning in elderly enriched with individuals at increased risk for Alzheimer's disease. European Journal of Nutrition. PMID 32472387 DOI: 10.1007/S00394-020-02257-6 |
0.356 |
|
| 2020 |
Maier F, Spottke A, Bach JP, Bartels C, Buerger K, Dodel R, Fellgiebel A, Fliessbach K, Frölich L, Hausner L, Hellmich M, Klöppel S, Klostermann A, Kornhuber J, Laske C, ... ... Wiltfang J, et al. Bupropion for the Treatment of Apathy in Alzheimer Disease: A Randomized Clinical Trial. Jama Network Open. 3: e206027. PMID 32463470 DOI: 10.1001/jamanetworkopen.2020.6027 |
0.428 |
|
| 2020 |
Rhein C, Mühle C, Lenz B, Richter-Schmidinger T, Kogias G, Boix F, Lourdusamy A, Dörfler A, Peters O, Ramirez A, Jessen F, Maier W, Hüll M, Frölich L, Teipel S, ... Wiltfang J, et al. Association of a CAMK2A genetic variant with logical memory performance and hippocampal volume in the elderly. Brain Research Bulletin. 161: 13-20. PMID 32418901 DOI: 10.1016/J.Brainresbull.2020.05.001 |
0.397 |
|
| 2020 |
Kleineidam L, Chouraki V, Próchnicki T, van der Lee SJ, Madrid-Márquez L, Wagner-Thelen H, Karaca I, Weinhold L, Wolfsgruber S, Boland A, Martino Adami PV, Lewczuk P, Popp J, Brosseron F, Jansen IE, ... ... Wiltfang J, et al. PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment. Acta Neuropathologica. PMID 32166339 DOI: 10.1007/S00401-020-02138-6 |
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Martins TS, Magalhães S, Rosa IM, Vogelgsang J, Wiltfang J, Delgadillo I, Catita J, da Cruz E Silva OAB, Nunes A, Henriques AG. Potential of FTIR Spectroscopy Applied to Exosomes for Alzheimer's Disease Discrimination: A Pilot Study. Journal of Alzheimer's Disease : Jad. PMID 32039849 DOI: 10.3233/Jad-191034 |
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Teuber-Hanselmann S, Rekowski J, Vogelgsang J, von Arnim C, Reetz K, Stang A, Jöckel KH, Wiltfang J, Esselmann H, Otto M, Tumani H, Herring A, Keyvani K. CSF and blood Kallikrein-8: a promising early biomarker for Alzheimer's disease. Journal of Neurology, Neurosurgery, and Psychiatry. 91: 40-48. PMID 31371645 DOI: 10.1136/jnnp-2019-321073 |
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Marizzoni M, Ferrari C, Babiloni C, Albani D, Barkhof F, Cavaliere L, Didic M, Forloni G, Fusco F, Galluzzi S, Hensch T, Jovicich J, Marra C, Molinuevo JL, Nobili F, ... ... Wiltfang J, et al. CSF cutoffs for MCI due to AD depend on APOEε4 carrier status. Neurobiology of Aging. PMID 32029236 DOI: 10.1016/J.Neurobiolaging.2019.12.019 |
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Teipel SJ, Kuper-Smith JO, Bartels C, Brosseron F, Buchmann M, Buerger K, Catak C, Janowitz D, Dechent P, Dobisch L, Ertl-Wagner B, Fließbach K, Haynes JD, Heneka MT, Kilimann I, ... ... Wiltfang J, et al. Multicenter Tract-Based Analysis of Microstructural Lesions within the Alzheimer's Disease Spectrum: Association with Amyloid Pathology and Diagnostic Usefulness. Journal of Alzheimer's Disease : Jad. PMID 31594223 DOI: 10.3233/Jad-190446 |
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Jain G, Stuendl A, Rao P, Berulava T, Pena Centeno T, Kaurani L, Burkhardt S, Delalle I, Kornhuber J, Hüll M, Maier W, Peters O, Esselmann H, Schulte C, Deuschle C, ... ... Wiltfang J, et al. A combined miRNA-piRNA signature to detect Alzheimer's disease. Translational Psychiatry. 9: 250. PMID 31591382 DOI: 10.1038/S41398-019-0579-2 |
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van Maurik IS, Vos SJ, Bos I, Bouwman FH, Teunissen CE, Scheltens P, Barkhof F, Frolich L, Kornhuber J, Wiltfang J, Maier W, Peters O, Rüther E, Nobili F, Frisoni GB, et al. Biomarker-based prognosis for people with mild cognitive impairment (ABIDE): a modelling study. The Lancet. Neurology. PMID 31526625 DOI: 10.1016/S1474-4422(19)30283-2 |
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Karsak M, Glebov K, Scheffold M, Bajaj T, Kawalia A, Karaca I, Rading S, Kornhuber J, Peters O, Diez-Fairen M, Frölich L, Hüll M, Wiltfang J, Scherer M, Riedel-Heller S, et al. A rare heterozygous TREM2 coding variant identified in familial clustering of dementia affects an intrinsically disordered protein region and function of TREM2. Human Mutation. PMID 31464095 DOI: 10.1002/Humu.23904 |
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Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Wiltfang J, et al. Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. PMID 31417202 DOI: 10.1038/s41588-019-0495-7 |
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Vogelgsang J, Wiltfang J. [New biomarkers for Alzheimer's disease in cerebrospinal fluid and blood]. Der Nervenarzt. 90: 907-913. PMID 31407045 DOI: 10.1007/S00115-019-0772-9 |
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Hessmann P, Zeidler J, Stahmeyer J, Eberhard S, Vogelgsang J, Abdel-Hamid M, Wolff-Menzler C, Wiltfang J, Kis B. Claims Data Analysis on the Dispensing of Tricyclic Antidepressants Among Patients With Dementia in Germany. Frontiers in Pharmacology. 10: 841. PMID 31396091 DOI: 10.3389/Fphar.2019.00841 |
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Miebach L, Wolfsgruber S, Polcher A, Peters O, Menne F, Luther K, Incesoy E, Priller J, Spruth E, Altenstein S, Buerger K, Catak C, Janowitz D, Perneczky R, Utecht J, ... ... Wiltfang J, et al. Which features of subjective cognitive decline are related to amyloid pathology? Findings from the DELCODE study. Alzheimer's Research & Therapy. 11: 66. PMID 31366409 DOI: 10.1186/S13195-019-0515-Y |
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Brueggen K, Dyrba M, Cardenas-Blanco A, Schneider A, Fliessbach K, Buerger K, Janowitz D, Peters O, Menne F, Priller J, Spruth E, Wiltfang J, Vukovich R, Laske C, Buchmann M, et al. Structural integrity in subjective cognitive decline, mild cognitive impairment and Alzheimer's disease based on multicenter diffusion tensor imaging. Journal of Neurology. PMID 31227891 DOI: 10.1007/S00415-019-09429-3 |
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Vogelgsang J, Vukovich R, Wedekind D, Wiltfang J. Higher Level of Mismatch in APOEε4 Carriers for Amyloid-Beta Peptide Alzheimer's Disease Biomarkers in Cerebrospinal Fluid. Asn Neuro. 11: 1759091419845524. PMID 31104469 DOI: 10.1177/1759091419845524 |
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Vogelgsang J, Heßmann P, Wolff-Menzler C, Gyßer S, Müller GA, Wiltfang J. Prevalence of affective disorders and dementia in inflammatory polyarthropathies. European Archives of Psychiatry and Clinical Neuroscience. PMID 31025090 DOI: 10.1007/S00406-019-01015-Y |
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Marizzoni M, Ferrari C, Macis A, Jovicich J, Albani D, Babiloni C, Cavaliere L, Didic M, Forloni G, Galluzzi S, Hoffmann KT, Molinuevo JL, Nobili F, Parnetti L, Payoux P, ... ... Wiltfang J, et al. Biomarker Matrix to Track Short Term Disease Progression in Amnestic Mild Cognitive Impairment Patients with Prodromal Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 30958351 DOI: 10.3233/Jad-181016 |
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Albrecht F, Mueller K, Ballarini T, Lampe L, Diehl-Schmid J, Fassbender K, Fliessbach K, Jahn H, Jech R, Kassubek J, Kornhuber J, Landwehrmeyer B, Lauer M, Ludolph AC, Lyros E, ... ... Wiltfang J, et al. Unraveling corticobasal syndrome and alien limb syndrome with structural brain imaging. Cortex; a Journal Devoted to the Study of the Nervous System and Behavior. 117: 33-40. PMID 30927559 DOI: 10.1016/J.Cortex.2019.02.015 |
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Nabers A, Hafermann H, Wiltfang J, Gerwert K. Aβ and tau structure-based biomarkers for a blood- and CSF-based two-step recruitment strategy to identify patients with dementia due to Alzheimer's disease. Alzheimer's & Dementia (Amsterdam, Netherlands). 11: 257-263. PMID 30911600 DOI: 10.1016/J.Dadm.2019.01.008 |
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Franzmeier N, Ren J, Damm A, Monté-Rubio G, Boada M, Ruiz A, Ramirez A, Jessen F, Düzel E, Rodríguez Gómez O, Benzinger T, Goate A, Karch CM, Fagan AM, McDade E, ... ... Wiltfang J, et al. The BDNF SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease. Molecular Psychiatry. PMID 30899092 DOI: 10.1038/S41380-019-0404-6 |
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Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Wiltfang J, et al. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. 51: 414-430. PMID 30820047 DOI: 10.1038/s41588-019-0358-2 |
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Santos JRF, Bauer C, Schuchhardt J, Wedekind D, Waniek K, Lachmann I, Wiltfang J, Vogelgsang J. Validation of a prototype tau Thr231 phosphorylation CSF ELISA as a potential biomarker for Alzheimer's disease. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 30767082 DOI: 10.1007/S00702-019-01982-5 |
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Bouter C, Vogelgsang J, Wiltfang J. Comparison between amyloid-PET and CSF amyloid-β biomarkers in a clinical cohort with memory deficits. Clinica Chimica Acta; International Journal of Clinical Chemistry. 492: 62-68. PMID 30735665 DOI: 10.1016/J.Cca.2019.02.005 |
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Hornung K, Zampar S, Engel N, Klafki H, Liepold T, Bayer TA, Wiltfang J, Jahn O, Wirths O. N-Terminal Truncated Aβ4-42 Is a Substrate for Neprilysin Degradation in vitro and in vivo. Journal of Alzheimer's Disease : Jad. 67: 849-858. PMID 30664509 DOI: 10.3233/Jad-181134 |
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Wolfsgruber S, Molinuevo JL, Wagner M, Teunissen CE, Rami L, Coll-Padrós N, Bouwman FH, Slot RER, Wesselman LMP, Peters O, Luther K, Buerger K, Priller J, Laske C, Teipel S, ... ... Wiltfang J, et al. Prevalence of abnormal Alzheimer's disease biomarkers in patients with subjective cognitive decline: cross-sectional comparison of three European memory clinic samples. Alzheimer's Research & Therapy. 11: 8. PMID 30654834 DOI: 10.1186/S13195-018-0463-Y |
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Meiberth DU, Hu X, Schild A, Spottke A, Brosseron F, Buerger K, Fliessbach K, Heneka MT, Kilimann I, Laske C, Peters O, Priller J, Schneider A, Teipel SJ, Wiltfang J, et al. P1-339: Cortical Thickness And Alzheimer'S Related Biomarkers In Subjective Cognitive Decline - Data From The Delcode-Study Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.894 |
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Hu X, Lee HL, Spottke A, Peters O, Priller J, Bürger K, Teipel SJ, Laske C, Wiltfang J, Düzel E, Jessen F. Ic-P-122: Alterations Of Intrinsic Connectivity In Posterior Default Mode Network Across At Risk Stages Of Alzheimer'S Dementia Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3980 |
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Sannemann L, Spottke A, Brosseron F, Buerger K, Fließbach K, Heneka MT, Kilimann I, Laske C, Peters O, Priller J, Schneider A, Teipel SJ, Wiltfang J, Wagner M, Düzel E, et al. P4-236: The Association Of Ad Pathology With Neuropsychiatric Symptoms And Worry In Subjective Cognitive Decline - Data From The Delcode Study Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3899 |
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Marzban EN, Teipel SJ, Buerger K, Fliessbach K, Heneka MT, Kilimann I, Laske C, Peters O, Priller J, Schneider A, Spottke A, Wagner M, Wiltfang J, Düzel E, Jessen F, et al. P3-361: Explainable Convolutional Networks And Multimodal Imaging Data: The Next Step Towards Using Artificial Intelligence As Diagnostic Tool For Early Detection Of Alzheimer'S Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3394 |
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Metzger CD, Dyrba M, Bittner D, Hu X, Teipel SJ, Grothe MJ, Peters O, Menne F, Fuentes M, Priller J, Spruth E, Franke C, Schneider A, Fliessbach K, Kofler B, ... Wiltfang J, et al. P1-407: Relationship Between Global Connectivity, Amyloid And Tau In Different Stages During The Development Of Alzheimer'S Disease As Demonstrated In The Dzne Delcode Cohort Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.1012 |
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Düzel E, Berron D, Schütze H, Cardenas-Blanco A, Metzger C, Betts M, Ziegler G, Chen Y, Dobisch L, Bittner D, Glanz W, Reuter M, Spottke A, Rudolph J, Brosseron F, ... ... Wiltfang J, et al. CSF total tau levels are associated with hippocampal novelty irrespective of hippocampal volume. Alzheimer's & Dementia (Amsterdam, Netherlands). 10: 782-790. PMID 30555890 DOI: 10.1016/J.Dadm.2018.10.003 |
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Shahpasand-Kroner H, Klafki HW, Bauer C, Schuchhardt J, Hüttenrauch M, Stazi M, Bouter C, Wirths O, Vogelgsang J, Wiltfang J. A two-step immunoassay for the simultaneous assessment of Aβ38, Aβ40 and Aβ42 in human blood plasma supports the Aβ42/Aβ40 ratio as a promising biomarker candidate of Alzheimer's disease. Alzheimer's Research & Therapy. 10: 121. PMID 30526652 DOI: 10.1186/S13195-018-0448-X |
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Walter S, Jumpertz T, Hüttenrauch M, Ogorek I, Gerber H, Storck SE, Zampar S, Dimitrov M, Lehmann S, Lepka K, Berndt C, Wiltfang J, Becker-Pauly C, Beher D, Pietrzik CU, et al. The metalloprotease ADAMTS4 generates N-truncated Aβ4-x species and marks oligodendrocytes as a source of amyloidogenic peptides in Alzheimer's disease. Acta Neuropathologica. PMID 30426203 DOI: 10.1007/S00401-018-1929-5 |
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Espinosa A, Hernández-Olasagarre B, Moreno-Grau S, Kleineidam L, Heilmann-Heimbach S, Hernández I, Wolfsgruber S, Wagner H, Rosende-Roca M, Mauleón A, Vargas L, Lafuente A, Rodríguez-Gómez O, Abdelnour C, Gil S, ... ... Wiltfang J, et al. Exploring Genetic Associations of Alzheimer's Disease Loci With Mild Cognitive Impairment Neurocognitive Endophenotypes. Frontiers in Aging Neuroscience. 10: 340. PMID 30425636 DOI: 10.3389/Fnagi.2018.00340 |
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Hüttenrauch M, Ogorek I, Klafki H, Otto M, Stadelmann C, Weggen S, Wiltfang J, Wirths O. Glycoprotein NMB: a novel Alzheimer's disease associated marker expressed in a subset of activated microglia. Acta Neuropathologica Communications. 6: 108. PMID 30340518 DOI: 10.1186/S40478-018-0612-3 |
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Steinacker P, Anderl-Straub S, Diehl-Schmid J, Semler E, Uttner I, von Arnim CAF, Barthel H, Danek A, Fassbender K, Fliessbach K, Foerstl H, Grimmer T, Huppertz HJ, Jahn H, Kassubek J, ... ... Wiltfang J, et al. Serum neurofilament light chain in behavioral variant frontotemporal dementia. Neurology. PMID 30209235 DOI: 10.1212/WNL.0000000000006318 |
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Bibl M, Gallus M, Welge V, Esselmann H, Wolf S, Rüther E, Wiltfang J. Correction to: Cerebrospinal fluid amyloid-β 2-42 is decreased in Alzheimer's, but not in frontotemporal dementia. Journal of Neural Transmission (Vienna, Austria : 1996). 125: 1515-1516. PMID 30159607 DOI: 10.1007/S00702-018-1914-0 |
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Albani D, Marizzoni M, Ferrari C, Fusco F, Boeri L, Raimondi I, Jovicich J, Babiloni C, Soricelli A, Lizio R, Galluzzi S, Cavaliere L, Didic M, Schönknecht P, Molinuevo JL, ... ... Wiltfang J, et al. Plasma Aβ42 as Biomarker of Prodromal Alzheimer's Disease Progression in Patients with Amnestic Mild Cognitive Impairment: Evidence from the PharmaCog/E-ADNI Study. Journal of Alzheimer's Disease : Jad. PMID 30149449 DOI: 10.3233/Jad-180321 |
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Vogelgsang J, Wolff-Menzler C, Kis B, Abdel-Hamid M, Wiltfang J, Hessmann P. Cardiovascular and metabolic comorbidities in patients with Alzheimer's disease and vascular dementia compared to a psychiatric control cohort. Psychogeriatrics : the Official Journal of the Japanese Psychogeriatric Society. PMID 29993172 DOI: 10.1111/Psyg.12338 |
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Joachim LK, Frölich L, Rüther E, Wiltfang J, Maier W, Kornhuber J, Bauer C, Heuser I, Peters O. Correlation of CSF- and MRI-Biomarkers and Progression of Cognitive Decline in an Open Label MCI Trial. The Journal of Prevention of Alzheimer's Disease. 5: 202-206. PMID 29972214 DOI: 10.14283/jpad.2018.5 |
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Marizzoni M, Ferrari C, Jovicich J, Albani D, Babiloni C, Cavaliere L, Didic M, Forloni G, Galluzzi S, Hoffmann KT, Molinuevo JL, Nobili F, Parnetti L, Payoux P, Ribaldi F, ... ... Wiltfang J, et al. Predicting and Tracking Short Term Disease Progression in Amnestic Mild Cognitive Impairment Patients with Prodromal Alzheimer's Disease: Structural Brain Biomarkers. Journal of Alzheimer's Disease : Jad. PMID 29914031 DOI: 10.3233/Jad-180152 |
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Denk J, Oberhauser F, Kornhuber J, Wiltfang J, Fassbender K, Schroeter ML, Volk AE, Diehl-Schmid J, Prudlo J, Danek A, Landwehrmeyer B, Lauer M, Otto M, Jahn H. Specific serum and CSF microRNA profiles distinguish sporadic behavioural variant of frontotemporal dementia compared with Alzheimer patients and cognitively healthy controls. Plos One. 13: e0197329. PMID 29746584 DOI: 10.1371/Journal.Pone.0197329 |
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Mattsson N, Groot C, Jansen WJ, Landau S, Villemagne V, Engelborghs S, Mintun M, Lleo A, Molinuevo JL, Jagust W, Frisoni GB, Ivanoiu A, Chételat G, Resende de Oliveira C, Rodrigue KM, ... ... Wiltfang J, et al. Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29601787 DOI: 10.1016/J.Jalz.2018.02.009 |
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Teunissen CE, Otto M, Engelborghs S, Herukka SK, Lehmann S, Lewczuk P, Lleó A, Perret-Liaudet A, Tumani H, Turner MR, Verbeek MM, Wiltfang J, Zetterberg H, Parnetti L, Blennow K. White paper by the Society for CSF Analysis and Clinical Neurochemistry: Overcoming barriers in biomarker development and clinical translation. Alzheimer's Research & Therapy. 10: 30. PMID 29544527 DOI: 10.1186/S13195-018-0359-X |
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Vogelgsang J, Shahpasand-Kroner H, Vogelgsang R, Streit F, Vukovich R, Wiltfang J. Multiplex immunoassay measurement of amyloid-βto amyloid-βratio in plasma discriminates between dementia due to Alzheimer's disease and dementia not due to Alzheimer's disease. Experimental Brain Research. PMID 29480353 DOI: 10.1007/S00221-018-5210-X |
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Franzmeier N, Düzel E, Jessen F, Buerger K, Levin J, Duering M, Dichgans M, Haass C, Suárez-Calvet M, Fagan AM, Paumier K, Benzinger T, Masters CL, Morris JC, Perneczky R, ... ... Wiltfang J, et al. Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer's disease. Brain : a Journal of Neurology. PMID 29462334 DOI: 10.1093/Brain/Awy008 |
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Vogelgsang J, Wedekind D, Bouter C, Klafki HW, Wiltfang J. Reproducibility of Alzheimer's Disease Cerebrospinal Fluid-Biomarker Measurements under Clinical Routine Conditions. Journal of Alzheimer's Disease : Jad. 62: 203-212. PMID 29439341 DOI: 10.3233/Jad-170793 |
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Schweda M, Kögel A, Bartels C, Wiltfang J, Schneider A, Schicktanz S. Prediction and Early Detection of Alzheimer's Dementia: Professional Disclosure Practices and Ethical Attitudes. Journal of Alzheimer's Disease : Jad. 62: 145-155. PMID 29439325 DOI: 10.3233/Jad-170443 |
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Jessen F, Spottke A, Boecker H, Brosseron F, Buerger K, Catak C, Fliessbach K, Franke C, Fuentes M, Heneka MT, Janowitz D, Kilimann I, Laske C, Menne F, Nestor P, ... ... Wiltfang J, et al. Design and first baseline data of the DZNE multicenter observational study on predementia Alzheimer's disease (DELCODE). Alzheimer's Research & Therapy. 10: 15. PMID 29415768 DOI: 10.1186/S13195-017-0314-2 |
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Meiberth DU, Hu X, Schild A, Spottke A, Brosseron F, Buerger K, Fliessbach K, Heneka MT, Kilimann I, Laske C, Peters O, Priller J, Schneider A, Teipel SJ, Wiltfang J, et al. P1-379: Cortical Thinning In Subjective Cognitive Decline With And Without Ad Pathology: Data From The Delcode Study Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.387 |
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| 2018 |
Miebach L, Wolfsgruber S, Frommann I, Roeske S, Oliver P, Buerger K, Nestor P, Ewers M, Laske C, Priller J, Schneider A, Spottke A, Heneka M, Teipel SJ, Wiltfang J, et al. F4-08-04: Subjective Cognitive Decline, As Measured With A Structured Interview, Is Related To Amyloid Pathology In Cognitively Healthy Older Adults Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2895 |
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Schipke CG, Menne F, Teipel SJ, Buerger K, Schneider A, Priller J, Christoph L, Wiltfang J, Spottke A, Heneka M, Brosseron F, Wagner M, Düzel E, Jessen F, Peters O. P4-068: Levels Of The Astrocyte-Derived Proteins Gfap And S100B In The Cerebrospinal Fluid Of Healthy Individuals And Alzheimer'S Disease Patients At Different Disease Stages Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2471 |
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Sannemann L, Hu X, Spottke A, Brosseron F, Buerger K, Fliessbach K, Heneka M, Kilimann I, Laske C, Peters O, Priller J, Schneider A, Teipel SJ, Wiltfang J, Wagner M, et al. P3-327: Neuropsychiatric Symptoms In At-Risk Groups For Ad Dementia And Their Relation To Ad Biomarkers: Data From The Delcode Study Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1688 |
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Brueggen K, Dyrba M, Cardenas-Blanco A, Nestor P, Schneider A, Buerger K, Peters O, Priller J, Wiltfang J, Laske C, Wagner M, Spottke A, Düzel E, Jessen F, Teipel SJ. Ic-P-155: Structural Integrity In Subjective Cognitive Decline, Mild Cognitive Impairment And Alzheimer'S Disease Based On Multicenter Diffusion Tensor Imaging: Results From The Delcode Study Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1148 |
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Kuper-Smith JO, Dyrba M, Brueggen K, Cardenas-Blanco A, Spottke A, Nestor P, Buerger K, Schneider A, Peters O, Priller J, Wiltfang J, Laske C, Düzel E, Jessen F, Teipel SJ. Ic-P-163: Microstructural Changes In Alzheimer'S Disease, Mild Cognitive Impairment, And Subjective Cognitive Decline Based On Multicenter Diffusion Tensor Imaging: A Tbss Analysis Of Delcode Data Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1139 |
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Jansen WJ, Ossenkoppele R, Tijms BM, Fagan AM, Hansson O, Klunk WE, van der Flier WM, Villemagne VL, Frisoni GB, Fleisher AS, Lleó A, Mintun MA, Wallin A, Engelborghs S, Na DL, ... ... Wiltfang J, et al. Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia. Jama Psychiatry. PMID 29188296 DOI: 10.1001/Jamapsychiatry.2017.3391 |
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Pereira CD, Martins F, Wiltfang J, da Cruz E Silva OAB, Rebelo S. ABC Transporters Are Key Players in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 29171999 DOI: 10.3233/Jad-170639 |
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Rosa IM, Henriques AG, Wiltfang J, da Cruz E Silva OAB. Putative Dementia Cases Fluctuate as a Function of Mini-Mental State Examination Cut-Off Points. Journal of Alzheimer's Disease : Jad. PMID 29125486 DOI: 10.3233/Jad-170501 |
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Lewczuk P, Riederer P, O'Bryant SE, Verbeek MM, Dubois B, Visser PJ, Jellinger KA, Engelborghs S, Ramirez A, Parnetti L, Jack CR, Teunissen CE, Hampel H, Lleó A, Jessen F, ... ... Wiltfang J, et al. Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 1-85. PMID 29076399 DOI: 10.1080/15622975.2017.1375556 |
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Frölich L, Peters O, Lewczuk P, Gruber O, Teipel SJ, Gertz HJ, Jahn H, Jessen F, Kurz A, Luckhaus C, Hüll M, Pantel J, Reischies FM, Schröder J, Wagner M, ... ... Wiltfang J, et al. Incremental value of biomarker combinations to predict progression of mild cognitive impairment to Alzheimer's dementia. Alzheimer's Research & Therapy. 9: 84. PMID 29017593 DOI: 10.1186/S13195-017-0301-7 |
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| 2017 |
Wirths O, Walter S, Kraus I, Klafki HW, Stazi M, Oberstein TJ, Ghiso J, Wiltfang J, Bayer TA, Weggen S. N-truncated Aβ4-x peptides in sporadic Alzheimer's disease cases and transgenic Alzheimer mouse models. Alzheimer's Research & Therapy. 9: 80. PMID 28978359 DOI: 10.1186/S13195-017-0309-Z |
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| 2017 |
Müller S, Preische O, Göpfert JC, Yañez VAC, Joos TO, Boecker H, Düzel E, Falkai P, Priller J, Buerger K, Catak C, Janowitz D, Heneka MT, Brosseron F, Nestor P, ... ... Wiltfang J, et al. Tau plasma levels in subjective cognitive decline: Results from the DELCODE study. Scientific Reports. 7: 9529. PMID 28842559 DOI: 10.1038/S41598-017-08779-0 |
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Schartner J, Nabers A, Budde B, Lange J, Hoeck N, Wiltfang J, Kötting C, Gerwert K. An ATR-FTIR Sensor Unraveling the Drug Intervention of Methylene Blue, Congo Red, and Berberine on Human Tau and Aβ. Acs Medicinal Chemistry Letters. 8: 710-714. PMID 28740603 DOI: 10.1021/Acsmedchemlett.7B00079 |
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| 2017 |
Wolfsgruber S, Polcher A, Koppara A, Kleineidam L, Frölich L, Peters O, Hüll M, Rüther E, Wiltfang J, Maier W, Kornhuber J, Lewczuk P, Jessen F, Wagner M. Cerebrospinal Fluid Biomarkers and Clinical Progression in Patients with Subjective Cognitive Decline and Mild Cognitive Impairment. Journal of Alzheimer's Disease : Jad. PMID 28527210 DOI: 10.3233/Jad-161252 |
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| 2017 |
Bos I, Vos SJ, Frölich L, Kornhuber J, Wiltfang J, Maier W, Peters O, Rüther E, Engelborghs S, Niemantsverdriet E, De Roeck EE, Tsolaki M, Freund-Levi Y, Johannsen P, Vandenberghe R, et al. The frequency and influence of dementia risk factors in prodromal Alzheimer's disease. Neurobiology of Aging. 56: 33-40. PMID 28482212 DOI: 10.1016/J.Neurobiolaging.2017.03.034 |
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| 2017 |
van der Ven A, Pape J, Hermann D, Schloesser R, Genius J, Fischer N, Mössnerf RM, Scherbaum N, Wiltfang J, Rujescu D, Benninghoff J. Methylene Blue (Tetramethylthionine Chloride) Influences the Mobility of Adult Neural Stem Cells: A Potentially Novel Therapeutic Mechanism of a Therapeutic Approach in the Treatment of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 28269766 DOI: 10.3233/Jad-160755 |
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| 2017 |
Nathan PJ, Lim YY, Abbott R, Galluzzi S, Marizzoni M, Babiloni C, Albani D, Bartres-Faz D, Didic M, Farotti L, Parnetti L, Salvadori N, Müller BW, Forloni G, Girtler N, ... ... Wiltfang J, et al. Association between CSF biomarkers, hippocampal volume and cognitive function in patients with amnestic mild cognitive impairment (MCI). Neurobiology of Aging. 53: 1-10. PMID 28189924 DOI: 10.1016/J.Neurobiolaging.2017.01.013 |
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| 2017 |
Vogelgsang J, Klafki H, Wedekind D, Bouter C, Wiltfang J. Reproducibility of Alzheimer's Disease CSF-Biomarker Measurements under Clinical Routine Conditions Pharmacopsychiatry. 50. DOI: 10.1055/S-0037-1606415 |
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| 2017 |
Franzmeier N, Wolfsgruber S, Ramirez A, Wagner M, Buerger K, Dichgans M, Heneka M, Falkai P, Teipel SJ, Wiltfang J, Priller J, Laske C, Schneider A, Spottke A, Duzel E, et al. [IC-P-030]: CONNECTIVITY OF THE LEFT FRONTAL CORTEX ATTENUATES DETRIMENTAL EFFECTS OF CSF-TAU ON MEMORY IN PRECLINICAL AND CLINICAL ALZHEIMER's DISEASE Alzheimer's & Dementia. 13: P28-P28. DOI: 10.1016/J.Jalz.2017.06.2302 |
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| 2016 |
Wiltfang J, Lewczuk P, Otto M. Biomarker bei Demenzen und anderen neurodegenerativen Erkrankungen: Aktuelle Entwicklungen Nervenarzt. 87: 1305-1309. PMID 27844089 DOI: 10.1007/S00115-016-0238-2 |
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| 2016 |
Klafki HW, Hafermann H, Bauer C, Haussmann U, Kraus I, Schuchhardt J, Muck S, Scherbaum N, Wiltfang J. Validation of a Commercial Chemiluminescence Immunoassay for the Simultaneous Measurement of Three Different Amyloid-β Peptides in Human Cerebrospinal Fluid and Application to a Clinical Cohort. Journal of Alzheimer's Disease : Jad. PMID 27567847 DOI: 10.3233/Jad-160398 |
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| 2016 |
Halbgebauer S, Nagl M, Klafki H, Haußmann U, Steinacker P, Oeckl P, Kassubek J, Pinkhardt E, Ludolph AC, Soininen H, Herukka SK, Wiltfang J, Otto M. Modified serpinA1 as risk marker for Parkinson's disease dementia: Analysis of baseline data. Scientific Reports. 6: 26145. PMID 27184740 DOI: 10.1038/Srep26145 |
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| 2016 |
Beyer I, Rezaei-Ghaleh N, Klafki HW, Jahn O, Haußmann U, Wiltfang J, Zweckstetter M, Knölker HJ. Solid-Phase Synthesis and Characterization of N-Terminally Elongated Aβ-3-x -Peptides. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27167300 DOI: 10.1002/Chem.201600892 |
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| 2016 |
Hüttenrauch M, Brauß A, Kurdakova A, Borgers H, Klinker F, Liebetanz D, Salinas-Riester G, Wiltfang J, Klafki HW, Wirths O. Physical activity delays hippocampal neurodegeneration and rescues memory deficits in an Alzheimer disease mouse model. Translational Psychiatry. 6. PMID 27138799 DOI: 10.1038/Tp.2016.65 |
0.363 |
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| 2016 |
Bey K, Wolfsgruber S, Karaca I, Wagner H, Lardenoije R, Becker J, Milz E, Kornhuber J, Peters O, Frölich L, Hüll M, Rüther E, Wiltfang J, Riedel-Heller S, Scherer M, et al. No association of the variant rs11887120 in DNMT3A with cognitive decline in individuals with mild cognitive impairment. Epigenomics. PMID 27092400 DOI: 10.2217/epi-2015-0014 |
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| 2016 |
Peters O, Heuser I, Frölich L, Rüther E, Rienhoff O, Kornhuber J, Wiltfang J, Maier W. [Dementia Competence Network. Results and outlook]. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz. 59: 438-43. PMID 26979717 DOI: 10.1007/S00103-016-2314-Y |
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| 2016 |
Lacour A, Espinosa A, Louwersheimer E, Heilmann S, Hernández I, Wolfsgruber S, Fernández V, Wagner H, Rosende-Roca M, Mauleón A, Moreno-Grau S, Vargas L, Pijnenburg YA, Koene T, Rodríguez-Gómez O, ... ... Wiltfang J, et al. Genome-wide significant risk factors for Alzheimer's disease: role in progression to dementia due to Alzheimer's disease among subjects with mild cognitive impairment. Molecular Psychiatry. PMID 26976043 DOI: 10.1038/Mp.2016.18 |
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| 2016 |
Lelental N, Brandner S, Kofanova O, Blennow K, Zetterberg H, Andreasson U, Engelborghs S, Mroczko B, Gabryelewicz T, Teunissen C, Mollenhauer B, Parnetti L, Chiasserini D, Molinuevo JL, Perret-Liaudet A, ... ... Wiltfang J, et al. Comparison of Different Matrices as Potential Quality Control Samples for Neurochemical Dementia Diagnostics. Journal of Alzheimer's Disease : Jad. PMID 26967210 DOI: 10.3233/Jad-150883 |
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| 2016 |
Reinert J, Richard BC, Klafki HW, Friedrich B, Bayer TA, Wiltfang J, Kovacs GG, Ingelsson M, Lannfelt L, Paetau A, Bergquist J, Wirths O. Deposition of C-terminally truncated Aβ species Aβ37 and Aβ39 in Alzheimer's disease and transgenic mouse models. Acta Neuropathologica Communications. 4: 24. PMID 26955942 DOI: 10.1186/S40478-016-0294-7 |
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| 2016 |
Galluzzi S, Marizzoni M, Babiloni C, Albani D, Antelmi L, Bagnoli C, Bartres-Faz D, Cordone S, Didic M, Farotti L, Fiedler U, Forloni G, Girtler N, Hensch T, Jovicich J, ... ... Wiltfang J, et al. Clinical and biomarker profiling of prodromal Alzheimer's disease in workpackage 5 of the Innovative Medicines Initiative PharmaCog project: a 'European ADNI study'. Journal of Internal Medicine. PMID 26940242 DOI: 10.1111/Joim.12482 |
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| 2016 |
Louwersheimer E, Wolfsgruber S, Espinosa A, Lacour A, Heilmann-Heimbach S, Alegret M, Hernández I, Rosende-Roca M, Tárraga L, Boada M, Kornhuber J, Peters O, Frölich L, Hüll M, Rüther E, ... Wiltfang J, et al. Alzheimer's disease risk variants modulate endophenotypes in mild cognitive impairment. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26921674 DOI: 10.1016/J.Jalz.2016.01.006 |
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| 2016 |
Nabers A, Ollesch J, Schartner J, Kötting C, Genius J, Hafermann H, Klafki H, Gerwert K, Wiltfang J. Amyloid-β-Secondary Structure Distribution in Cerebrospinal Fluid and Blood Measured by an Immuno-Infrared-Sensor: A Biomarker Candidate for Alzheimer's Disease. Analytical Chemistry. 88: 2755-62. PMID 26828829 DOI: 10.1021/acs.analchem.5b04286 |
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| 2016 |
van Waalwijk van Doorn LJ, Koel-Simmelink MJ, Haußmann U, Klafki H, Struyfs H, Linning P, Knölker HJ, Twaalfhoven H, Kuiperij HB, Engelborghs S, Scheltens P, Verbeek MM, Vanmechelen E, Wiltfang J, Teunissen CE. Validation of soluble APP assays as diagnostic CSF biomarkers for neurodegenerative diseases. Journal of Neurochemistry. PMID 26748905 DOI: 10.1111/Jnc.13527 |
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| 2016 |
Nabers A, Ollesch J, Schartner J, Kötting C, Genius J, Haußmann U, Klafki H, Wiltfang J, Gerwert K. An infrared sensor analysing label-free the secondary structure of the Abeta peptide in presence of complex fluids. Journal of Biophotonics. 9: 224-34. PMID 25808829 DOI: 10.1002/Jbio.201400145 |
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| 2016 |
Suppa P, Schipke CG, Spies L, Wiltfang J, Peters O. P4-174: Evaluation of Cutoff Values For Fully Automated Hippocampus Volumetry With Fsl-First For Prediction Of Alzheimer's Disease Dementia In Mci Subjects Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.2266 |
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| 2016 |
Bos I, Vos S, Frölich L, Kornhuber J, Wiltfang J, Maier W, Peters O, Rüther E, Engelborghs S, Niemantsverdriet E, Roeck ED, Tsolaki M, Freund-Levi Y, Johannsen P, Vandenberghe R, et al. Prevalence of vasculare risk factors in different stages of prodromal Alzheimer’s disease and its influence on cognitive decline Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.2213 |
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| 2015 |
Peters O, Fuentes M, Joachim LK, Jessen F, Luckhaus C, Kornhuber J, Pantel J, Hüll M, Schmidtke K, Rüther E, Möller HJ, Kurz A, Wiltfang J, Maier W, Wiese B, et al. Combined treatment with memantine and galantamine-CR compared with galantamine-CR only in antidementia drug naïve patients with mild-to-moderate Alzheimer's disease. Alzheimer's & Dementia (New York, N. Y.). 1: 198-204. PMID 29854939 DOI: 10.1016/J.Trci.2015.10.001 |
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| 2015 |
Lewczuk P, Kornhuber J, Toledo JB, Trojanowski JQ, Knapik-Czajka M, Peters O, Wiltfang J, Shaw LM. Validation of the Erlangen Score Algorithm for the Prediction of the Development of Dementia due to Alzheimer's Disease in Pre-Dementia Subjects. Journal of Alzheimer's Disease : Jad. 49: 887. PMID 26682863 DOI: 10.3233/JAD-159006 |
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| 2015 |
Savastano A, Klafki H, Haußmann U, Oberstein TJ, Muller P, Wirths O, Wiltfang J, Bayer TA. N-Truncated Aβ2-X Starting with Position Two in Sporadic Alzheimer's Disease Cases and Two Alzheimer Mouse Models. Journal of Alzheimer's Disease : Jad. 49: 101-10. PMID 26529393 DOI: 10.3233/Jad-150394 |
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| 2015 |
Koppara A, Wolfsgruber S, Kleineidam L, Schmidtke K, Frölich L, Kurz A, Schulz S, Hampel H, Heuser I, Peters O, Reischies FM, Jahn H, Luckhaus C, Hüll M, Gertz HJ, ... ... Wiltfang J, et al. The Latent Dementia Phenotype δ is Associated with Cerebrospinal Fluid Biomarkers of Alzheimer's Disease and Predicts Conversion to Dementia in Subjects with Mild Cognitive Impairment. Journal of Alzheimer's Disease : Jad. PMID 26484902 DOI: 10.3233/Jad-150257 |
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| 2015 |
Bouter Y, Noguerola JS, Tucholla P, Crespi GA, Parker MW, Wiltfang J, Miles LA, Bayer TA. Abeta targets of the biosimilar antibodies of Bapineuzumab, Crenezumab, Solanezumab in comparison to an antibody against N-truncated Abeta in sporadic Alzheimer disease cases and mouse models. Acta Neuropathologica. PMID 26467270 DOI: 10.1007/S00401-015-1489-X |
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Savastano A, Klafki H, Haußmann U, Oberstein TJ, Muller P, Wirths O, Wiltfang J, Bayer TA. N-Truncated Aβ 2-X Starting with Position Two in Sporadic Alzheimer's Disease Cases and Two Alzheimer Mouse Models. Journal of Alzheimer's Disease : Jad. PMID 26444772 DOI: 10.3233/JAD-150349 |
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Noreik M, Kuhn J, Hardenacke K, Lenartz D, Bauer A, Bührle CP, Häussermann P, Hellmich M, Klosterkötter J, Wiltfang J, Maarouf M, Freund HJ, Visser-Vandewalle V, Sturm V, Schulz RJ. Changes in Nutritional Status after Deep Brain Stimulation of the Nucleus Basalis of Meynert in Alzheimer's Disease - Results of a Phase I Study. The Journal of Nutrition, Health & Aging. 19: 812-8. PMID 26412285 DOI: 10.1007/s12603-015-0496-x |
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Lewczuk P, Kornhuber J, Toledo JB, Trojanowski JQ, Knapik-Czajka M, Peters O, Wiltfang J, Shaw LM. Validation of the Erlangen Score Algorithm for the Prediction of the Development of Dementia due to Alzheimer's Disease in Pre-Dementia Subjects. Journal of Alzheimer's Disease : Jad. 48: 433-41. PMID 26402007 DOI: 10.3233/Jad-150342 |
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Jansen WJ, Ossenkoppele R, Knol DL, Tijms BM, Scheltens P, Verhey FR, Visser PJ, Aalten P, Aarsland D, Alcolea D, Alexander M, Almdahl IS, Arnold SE, Baldeiras I, ... ... Wiltfang J, et al. Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis. Jama. 313: 1924-38. PMID 25988462 DOI: 10.1001/Jama.2015.4668 |
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Morgen K, Schneider M, Frölich L, Tost H, Plichta MM, Kölsch H, Rakebrandt F, Rienhoff O, Jessen F, Peters O, Jahn H, Luckhaus C, Hüll M, Gertz HJ, Schröder J, ... ... Wiltfang J, et al. Apolipoprotein E-dependent load of white matter hyperintensities in Alzheimer's disease: a voxel-based lesion mapping study. Alzheimer's Research & Therapy. 7: 27. PMID 25984242 DOI: 10.1186/S13195-015-0111-8 |
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Moreno F, Rabinovici GD, Karydas A, Miller Z, Hsu SC, Legati A, Fong J, Schonhaut D, Esselmann H, Watson C, Stephens ML, Kramer J, Wiltfang J, Seeley WW, Miller BL, et al. A novel mutation P112H in the TARDBP gene associated with frontotemporal lobar degeneration without motor neuron disease and abundant neuritic amyloid plaques. Acta Neuropathologica Communications. 3: 19. PMID 25853458 DOI: 10.1186/S40478-015-0190-6 |
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Heilmann S, Drichel D, Clarimon J, Fernández V, Lacour A, Wagner H, Thelen M, Hernández I, Fortea J, Alegret M, Blesa R, Mauleón A, Roca MR, Kornhuber J, Peters O, ... ... Wiltfang J, et al. PLD3 in non-familial Alzheimer's disease. Nature. 520: E3-5. PMID 25832411 DOI: 10.1038/Nature14039 |
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Wiltfang J. Neue diagnostische Methoden bei Demenzen Nervenarzt. 86: 452-460. PMID 25801947 DOI: 10.1007/S00115-014-4177-5 |
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Wiltfang J. Cerebrospinal fluid markers in early diagnosis of Alzheimer dementia Therapeutische Umschau. Revue théRapeutique. 72: 271-278. PMID 25791051 DOI: 10.1024/0040-5930/A000675 |
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Wolfsgruber S, Jessen F, Koppara A, Kleineidam L, Schmidtke K, Frölich L, Kurz A, Schulz S, Hampel H, Heuser I, Peters O, Reischies FM, Jahn H, Luckhaus C, Hüll M, ... ... Wiltfang J, et al. Subjective cognitive decline is related to CSF biomarkers of AD in patients with MCI. Neurology. 84: 1261-8. PMID 25716354 DOI: 10.1212/Wnl.0000000000001399 |
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Vos SJ, Verhey F, Frölich L, Kornhuber J, Wiltfang J, Maier W, Peters O, Rüther E, Nobili F, Morbelli S, Frisoni GB, Drzezga A, Didic M, van Berckel BN, Simmons A, et al. Prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage. Brain : a Journal of Neurology. 138: 1327-38. PMID 25693589 DOI: 10.1093/Brain/Awv029 |
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Louwersheimer E, Ramirez A, Cruchaga C, Becker T, Kornhuber J, Peters O, Heilmann S, Wiltfang J, Jessen F, Visser PJ, Scheltens P, Pijnenburg YA, Teunissen CE, Barkhof F, van Swieten JC, et al. The influence of genetic variants in SORL1 gene on the manifestation of Alzheimer's disease. Neurobiology of Aging. 36: 1605.e13-20. PMID 25659857 DOI: 10.1016/J.Neurobiolaging.2014.12.007 |
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Popp J, Wolfsgruber S, Heuser I, Peters O, Hüll M, Schröder J, Möller HJ, Lewczuk P, Schneider A, Jahn H, Luckhaus C, Perneczky R, Frölich L, Wagner M, Maier W, ... Wiltfang J, et al. Cerebrospinal fluid cortisol and clinical disease progression in MCI and dementia of Alzheimer's type. Neurobiology of Aging. 36: 601-7. PMID 25435336 DOI: 10.1016/J.Neurobiolaging.2014.10.031 |
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| 2015 |
Oberstein TJ, Spitzer P, Klafki HW, Linning P, Neff F, Knölker HJ, Lewczuk P, Wiltfang J, Kornhuber J, Maler JM. Astrocytes and microglia but not neurons preferentially generate N-terminally truncated Aβ peptides. Neurobiology of Disease. 73: 24-35. PMID 25204716 DOI: 10.1016/J.Nbd.2014.08.031 |
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Kuhn J, Hardenacke K, Lenartz D, Gruendler T, Ullsperger M, Bartsch C, Mai JK, Zilles K, Bauer A, Matusch A, Schulz RJ, Noreik M, Bührle CP, Maintz D, Woopen C, ... ... Wiltfang J, et al. Deep brain stimulation of the nucleus basalis of Meynert in Alzheimer's dementia. Molecular Psychiatry. 20: 353-60. PMID 24798585 DOI: 10.1038/Mp.2014.32 |
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Esselmann H, Hafermann C, Jahn O, Kraus I, Vogelgsang J, Haußmann U, Uecker M, Liepold T, Klafki H, Wiltfang J. Analytical methods to explore Amyloid-β-Peptide variants beyond Aβ1-40 and Aβ1-42 Pharmacopsychiatry. 25. DOI: 10.1055/S-0035-1557950 |
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| 2015 |
Peters O, Fuentes M, Joachim LK, Jessen F, Luckhaus C, Kornhuber J, Pantel J, Hüll M, Schmidtke K, Rüther E, Möller HJ, Kurz A, Wiltfang J, Maier W, Wiese B, et al. Combined treatment with memantine and galantamine-CR compared with galantamine-CR only in antidementia drug naïve patients with mild-to-moderate Alzheimer's disease Alzheimer's and Dementia: Translational Research and Clinical Interventions. 1: 198-204. DOI: 10.1016/j.trci.2015.10.001 |
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| 2015 |
Wolfsgruber S, Polcher AA, Koppara A, Kleineidam L, Schmidtke K, Frölich L, Hampel H, Heuser I, Peters O, Jahn H, Luckhaus C, Reischies FM, Hüll M, Gertz H, Schröder J, ... ... Wiltfang J, et al. Using neuropsychological criteria to distinguish between memory clinic patients with subjective cognitive decline and MCI Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.08.102 |
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| 2015 |
Louwersheimer E, Wolfsgruber S, Espinosa A, Lacour A, Heilman S, Alegret M, Hernandez I, Rosende-Roca M, Tarraga L, Kornhuber J, Peters O, Frölich L, Hüll M, Rüther E, Wiltfang J, et al. O4-05-04: A four-center study on the effect of polygenic risk score on cerebrospinal fluid markers and memory decline in mild cognitive impairment patients Alzheimer's & Dementia. 11: P279-P279. DOI: 10.1016/J.Jalz.2015.07.372 |
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| 2015 |
Koppara A, Wolfsgruber S, Kleineidam L, Schmidtke K, Frölich L, Kurz A, Schulz S, Hampel H, Heuser I, Peters O, Reischies FM, Jahn H, Luckhaus C, Hüll M, Gertz H, ... ... Wiltfang J, et al. The latent dementia phenotype δ is associated with the CSF Alzheimer's disease biomarker signature in subjects with mild cognitive impairment Alzheimers & Dementia. 11: 176. DOI: 10.1016/J.Jalz.2015.07.139 |
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Doorn LJCvWv, Koel-Simmelink MJ, Hausmann U, Klafki H, Struyfs H, Linning P, Knoelker H, Twaalfhoven H, Kuiperij HB, Vanmechelen E, Verbeek M, Engelborghs S, Wiltfang J, Teunissen CE. Standardization of a method for diagnostic biomarker validation for neurodegenerative diseases: App assays as example Alzheimers & Dementia. 11: 387. DOI: 10.1016/J.Jalz.2015.06.318 |
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Wiltfang J. Klinisch-validierte molekulare Biomarker neurodegenerativer Demenzerkrankungen Nervenarzt. 85: 1372-1381. PMID 25331214 DOI: 10.1007/S00115-014-4086-7 |
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| 2014 |
Thelen M, Razquin C, Hernández I, Gorostidi A, Sánchez-Valle R, Ortega-Cubero S, Wolfsgruber S, Drichel D, Fliessbach K, Duenkel T, Damian M, Heilmann S, Slotosch A, Lennarz M, Seijo-Martínez M, ... ... Wiltfang J, et al. Investigation of the role of rare TREM2 variants in frontotemporal dementia subtypes. Neurobiology of Aging. 35: 2657.e13-9. PMID 25042114 DOI: 10.1016/J.Neurobiolaging.2014.06.018 |
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| 2014 |
Ramirez A, van der Flier WM, Herold C, Ramonet D, Heilmann S, Lewczuk P, Popp J, Lacour A, Drichel D, Louwersheimer E, Kummer MP, Cruchaga C, Hoffmann P, Teunissen C, Holstege H, ... ... Wiltfang J, et al. SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease. Human Molecular Genetics. 23: 6644-58. PMID 25027320 DOI: 10.1093/Hmg/Ddu372 |
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| 2014 |
Wolfsgruber S, Wagner M, Schmidtke K, Frölich L, Kurz A, Schulz S, Hampel H, Heuser I, Peters O, Reischies FM, Jahn H, Luckhaus C, Hüll M, Gertz HJ, Schröder J, ... ... Wiltfang J, et al. Memory concerns, memory performance and risk of dementia in patients with mild cognitive impairment. Plos One. 9: e100812. PMID 25019225 DOI: 10.1371/Journal.Pone.0100812 |
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| 2014 |
Morgen K, Ramirez A, Frölich L, Tost H, Plichta MM, Kölsch H, Rakebrandt F, Rienhoff O, Jessen F, Peters O, Jahn H, Luckhaus C, Hüll M, Gertz HJ, Schröder J, ... ... Wiltfang J, et al. Genetic interaction of PICALM and APOE is associated with brain atrophy and cognitive impairment in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: S269-76. PMID 24613704 DOI: 10.1016/J.Jalz.2013.11.001 |
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| 2014 |
Deuschle M, Schilling C, Leweke FM, Enning F, Pollmächer T, Esselmann H, Wiltfang J, Frölich L, Heuser I. Hypocretin in cerebrospinal fluid is positively correlated with Tau and pTau. Neuroscience Letters. 561: 41-5. PMID 24373987 DOI: 10.1016/J.Neulet.2013.12.036 |
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| 2014 |
Baptista FI, Henriques AG, Silva AM, Wiltfang J, da Cruz e Silva OA. Flavonoids as therapeutic compounds targeting key proteins involved in Alzheimer's disease. Acs Chemical Neuroscience. 5: 83-92. PMID 24328060 DOI: 10.1021/Cn400213R |
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| 2014 |
Fritschi SK, Langer F, Kaeser SA, Maia LF, Maetzler W, Keyvani K, Spitzer P, Wiltfang J, Staufenbiel M, Jucker M. HIGHLY POTENT SOLUBLE Aβ SEEDS IN HUMAN ALZHEIMER BRAIN BUT NOT CEREBROSPINAL FLUID Alzheimers & Dementia. 10. DOI: 10.1016/J.Jalz.2014.05.1580 |
0.375 |
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| 2013 |
Morgen K, Frölich L, Tost H, Plichta MM, Kölsch H, Rakebrandt F, Rienhoff O, Jessen F, Peters O, Jahn H, Luckhaus C, Hüll M, Gertz HJ, Schröder J, Hampel H, ... ... Wiltfang J, et al. APOE-dependent phenotypes in subjects with mild cognitive impairment converting to Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 37: 389-401. PMID 23948881 DOI: 10.3233/Jad-130326 |
0.488 |
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| 2013 |
Bibl M, Esselmann H, Wiltfang J. Neurochemical biomarkers in Alzheimer's disease and related disorders. Therapeutic Advances in Neurological Disorders. 5: 335-48. PMID 23139704 DOI: 10.1177/1756285612455367 |
0.368 |
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| 2013 |
Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Williams A, Jones N, Thomas C, Stretton A, Morgan AR, Lovestone S, ... ... Wiltfang J, et al. Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease Nature Genetics. 45: 712-712. DOI: 10.1038/Ng0613-712A |
0.385 |
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| 2013 |
Wolfsgruber S, Wagner M, Wiltfang J, Maier W, Frolich L, Peters O, Rüther E, Klaus S, Heuser I, Kornhuber J, Jessen F. P4-154: Subjective memory concerns, objective memory impairment and risk of Alzheimer's dementia in people with MCI Alzheimer's & Dementia. 9: P761-P762. DOI: 10.1016/J.Jalz.2013.05.1545 |
0.381 |
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| 2012 |
Genius J, Klafki H, Benninghoff J, Esselmann H, Wiltfang J. Current application of neurochemical biomarkers in the prediction and differential diagnosis of Alzheimer's disease and other neurodegenerative dementias. European Archives of Psychiatry and Clinical Neuroscience. 262: 71-77. PMID 22986448 DOI: 10.1007/S00406-012-0362-3 |
0.454 |
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| 2012 |
Bibl M, Welge V, Schmidt H, Esselmann H, Mollenhauer B, Lewczuk P, Otto M, Kornhuber J, Wiltfang J. Plasma amyloid-beta peptides in acute cerebral ischemia: a pilot study. Journal of Clinical Laboratory Analysis. 26: 238-45. PMID 22811355 DOI: 10.1002/Jcla.21511 |
0.348 |
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| 2012 |
Fiedler U, Wiltfang J, Peters N, Benninghoff J. [Advances in the diagnostics of Alzheimer's disease]. Der Nervenarzt. 83: 661-73. PMID 22576052 DOI: 10.1007/S00115-012-3486-9 |
0.405 |
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| 2012 |
Bibl M, Gallus M, Welge V, Esselmann H, Wolf S, Rüther E, Wiltfang J. Cerebrospinal fluid amyloid-β 2-42 is decreased in Alzheimer's, but not in frontotemporal dementia. Journal of Neural Transmission (Vienna, Austria : 1996). 119: 805-13. PMID 22527776 DOI: 10.1007/S00702-012-0801-3 |
0.368 |
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| 2012 |
Bibl M, Gallus M, Welge V, Esselmann H, Wiltfang J. Aminoterminally truncated and oxidized amyloid-β peptides in the cerebrospinal fluid of Alzheimer's disease patients. Journal of Alzheimer's Disease : Jad. 29: 809-16. PMID 22460324 DOI: 10.3233/JAD-2012-111796 |
0.34 |
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| 2012 |
Henkel AW, Müller K, Lewczuk P, Müller T, Marcus K, Kornhuber J, Wiltfang J. Multidimensional plasma protein separation technique for identification of potential Alzheimer's disease plasma biomarkers: a pilot study. Journal of Neural Transmission (Vienna, Austria : 1996). 119: 779-88. PMID 22415063 DOI: 10.1007/S00702-012-0781-3 |
0.462 |
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| 2012 |
Wagner M, Wolf S, Reischies FM, Daerr M, Wolfsgruber S, Jessen F, Popp J, Maier W, Hüll M, Frölich L, Hampel H, Perneczky R, Peters O, Jahn H, Luckhaus C, ... ... Wiltfang J, et al. Biomarker validation of a cued recall memory deficit in prodromal Alzheimer disease. Neurology. 78: 379-86. PMID 22238414 DOI: 10.1212/Wnl.0B013E318245F447 |
0.524 |
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| 2012 |
Schrijvers EM, Schürmann B, Koudstaal PJ, van den Bussche H, Van Duijn CM, Hentschel F, Heun R, Hofman A, Jessen F, Kölsch H, Kornhuber J, Peters O, Rivadeneira F, Rüther E, Uitterlinden AG, ... ... Wiltfang J, et al. Genome-wide association study of vascular dementia. Stroke; a Journal of Cerebral Circulation. 43: 315-9. PMID 22116812 DOI: 10.1161/Strokeaha.111.628768 |
0.38 |
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| 2012 |
Gerrish A, Russo G, Richards A, Moskvina V, Ivanov D, Harold D, Sims R, Abraham R, Hollingworth P, Chapman J, Hamshere M, Pahwa JS, Dowzell K, Williams A, Jones N, ... ... Wiltfang J, et al. The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 28: 377-87. PMID 22027014 DOI: 10.3233/Jad-2011-110824 |
0.44 |
|
| 2011 |
Spitzer P, Schieb H, Kamrowski-Kruck H, Otto M, Chiasserini D, Parnetti L, Herukka SK, Schuchhardt J, Wiltfang J, Klafki HW. Evidence for Elevated Cerebrospinal Fluid ERK1/2 Levels in Alzheimer Dementia. International Journal of Alzheimer's Disease. 2011: 739847. PMID 22145083 DOI: 10.4061/2011/739847 |
0.354 |
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| 2011 |
Teipel SJ, Peters O, Heuser I, Jessen F, Maier W, Froelich L, Arlt S, Hüll M, Gertz HJ, Kornhuber J, Wiltfang J, Thome J, Rienhoff O, Meindl T, Hampel H, et al. Atrophy outcomes in multicentre clinical trials on Alzheimer's disease: effect of different processing and analysis approaches on sample sizes. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 12: 109-13. PMID 21906007 DOI: 10.3109/15622975.2011.603222 |
0.395 |
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| 2011 |
Jessen F, Lewczuk P, Gür O, Block W, Ende G, Frölich L, Hammen T, Arlt S, Kornhuber J, Kucinski T, Popp J, Peters O, Maier W, Träber F, Wiltfang J. Association of N-acetylaspartate and cerebrospinal fluid Aβ42 in dementia. Journal of Alzheimer's Disease : Jad. 27: 393-9. PMID 21841259 DOI: 10.3233/Jad-2011-110398 |
0.493 |
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| 2011 |
Schieb H, Kratzin H, Jahn O, Möbius W, Rabe S, Staufenbiel M, Wiltfang J, Klafki HW. Beta-amyloid peptide variants in brains and cerebrospinal fluid from amyloid precursor protein (APP) transgenic mice: comparison with human Alzheimer amyloid. The Journal of Biological Chemistry. 286: 33747-58. PMID 21795681 DOI: 10.1074/jbc.M111.246561 |
0.312 |
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| 2011 |
Hermann DM, Keyvani K, van de Nes J, Weimar C, Wiltfang J, Nitsch RM, Szodorai A. Brain-reactive β-amyloid antibodies in primary CNS angiitis with cerebral amyloid angiopathy. Neurology. 77: 503-5. PMID 21775736 DOI: 10.1212/Wnl.0B013E318227B250 |
0.358 |
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| 2011 |
Schipke CG, Jessen F, Teipel S, Luckhaus C, Wiltfang J, Esselmann H, Frölich L, Maier W, Rüther E, Heppner FL, Prokop S, Heuser I, Peters O. Long-term stability of Alzheimer's disease biomarker proteins in cerebrospinal fluid. Journal of Alzheimer's Disease : Jad. 26: 255-62. PMID 21606567 DOI: 10.3233/Jad-2011-110329 |
0.323 |
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| 2011 |
Frings L, Klöppel S, Teipel S, Peters O, Frölich L, Pantel J, Schröder J, Gertz HJ, Arlt S, Heuser I, Kornhuber J, Wiltfang J, Maier W, Jessen F, Hampel H, et al. Left anterior temporal lobe sustains naming in Alzheimer's dementia and mild cognitive impairment. Current Alzheimer Research. 8: 893-901. PMID 21592050 DOI: 10.2174/156720511798192673 |
0.497 |
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| 2011 |
Hollingworth P, Harold D, Sims R, Gerrish A, Lambert JC, Carrasquillo MM, Abraham R, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Jones N, Stretton A, Thomas C, Richards A, ... ... Wiltfang J, et al. Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nature Genetics. 43: 429-35. PMID 21460840 DOI: 10.1038/Ng.803 |
0.343 |
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| 2011 |
Mollenhauer B, Esselmann H, Trenkwalder C, Schulz-Schaeffer W, Kretzschmar H, Otto M, Wiltfang J, Bibl M. CSF amyloid-β peptides in neuropathologically diagnosed dementia with Lewy bodies and Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 24: 383-91. PMID 21297274 DOI: 10.3233/JAD-2011-101551 |
0.376 |
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| 2011 |
Mollenhauer B, Esselmann H, Roeber S, Schulz-Schaeffer WJ, Trenkwalder C, Bibl M, Steinacker P, Kretzschmar HA, Wiltfang J, Otto M. Different CSF β-amyloid processing in Alzheimer's and Creutzfeldt-Jakob disease. Journal of Neural Transmission (Vienna, Austria : 1996). 118: 691-7. PMID 21210287 DOI: 10.1007/s00702-010-0543-z |
0.356 |
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| 2011 |
Bibl M, Mollenhauer B, Lewczuk P, Esselmann H, Wolf S, Otto M, Kornhuber J, Rüther E, Wiltfang J. Cerebrospinal fluid tau, p-tau 181 and amyloid-β38/40/42 in frontotemporal dementias and primary progressive aphasias. Dementia and Geriatric Cognitive Disorders. 31: 37-44. PMID 21135556 DOI: 10.1159/000322370 |
0.485 |
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| 2011 |
Ott S, Henkel AW, Henkel MK, Redzic ZB, Kornhuber J, Wiltfang J. Pre-aggregated Aβ1-42 peptide increases tau aggregation and hyperphosphorylation after short-term application. Molecular and Cellular Biochemistry. 349: 169-77. PMID 21113648 DOI: 10.1007/S11010-010-0671-7 |
0.463 |
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| 2011 |
Jones L, Holmans PA, Hamshere ML, Harold D, Moskvina V, Ivanov D, Pocklington A, Abraham R, Hollingworth P, Sims R, Gerrish A, Pahwa JS, Jones N, Stretton A, Morgan AR, ... ... Wiltfang J, et al. Correction: Genetic Evidence Implicates the Immune System and Cholesterol Metabolism in the Aetiology of Alzheimer's Disease Plos One. 6. DOI: 10.1371/annotation/a0bb886d-d345-4a20-a82e-adce9b047798 |
0.369 |
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| 2011 |
Bibl M, Esselmann H, Mollenhauer B, Trenkwalder C, Schulz-Schaeffer W, Kretzschmar H, Otto M, Wiltfang J. P1-132: CSF Aβ peptides in neuropathologically diagnosed dementias with lewy bodies and Alzheimer's type Alzheimer's & Dementia. 7: S153-S153. DOI: 10.1016/j.jalz.2011.05.412 |
0.322 |
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| 2010 |
Jones L, Holmans PA, Hamshere ML, Harold D, Moskvina V, Ivanov D, Pocklington A, Abraham R, Hollingworth P, Sims R, Gerrish A, Pahwa JS, Jones N, Stretton A, Morgan AR, ... ... Wiltfang J, et al. Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease. Plos One. 5: e13950. PMID 21085570 DOI: 10.1371/Journal.Pone.0013950 |
0.384 |
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| 2010 |
Spitzer P, Herrmann M, Klafki HW, Smirnov A, Lewczuk P, Kornhuber J, Wiltfang J, Maler JM. Phagocytosis and LPS alter the maturation state of β-amyloid precursor protein and induce different Aβ peptide release signatures in human mononuclear phagocytes. Journal of Neuroinflammation. 7: 59. PMID 20929546 DOI: 10.1186/1742-2094-7-59 |
0.433 |
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| 2010 |
Bibl M, Esselmann H, Lewczuk P, Trenkwalder C, Otto M, Kornhuber J, Wiltfang J, Mollenhauer B. Combined Analysis of CSF Tau, Aβ42, Aβ1-42% and Aβ1-40% in Alzheimer's Disease, Dementia with Lewy Bodies and Parkinson's Disease Dementia. International Journal of Alzheimer's Disease. 2010. PMID 20862375 DOI: 10.4061/2010/761571 |
0.516 |
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| 2010 |
Mohamadi MR, Svobodova Z, Verpillot R, Esselmann H, Wiltfang J, Otto M, Taverna M, Bilkova Z, Viovy JL. Microchip electrophoresis profiling of Aβ peptides in the cerebrospinal fluid of patients with Alzheimer's disease. Analytical Chemistry. 82: 7611-7. PMID 20722394 DOI: 10.1021/Ac101337N |
0.321 |
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| 2010 |
Schmidt D, Zimmermann R, Lewczuk P, Schaller G, Degirmenci U, Kreil S, Wiltfang J, Kuwert T, Kornhuber J, Weih M. Confirmation rate of blinded (99m)Tc-SPECT compared to neurochemical dementia biomarkers in CSF in patients with Alzheimer disease. Journal of Neural Transmission (Vienna, Austria : 1996). 117: 1111-4. PMID 20694486 DOI: 10.1007/S00702-010-0459-7 |
0.466 |
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| 2010 |
Teipel SJ, Ewers M, Wolf S, Jessen F, Kölsch H, Arlt S, Luckhaus C, Schönknecht P, Schmidtke K, Heuser I, Frölich L, Ende G, Pantel J, Wiltfang J, Rakebrandt F, et al. Multicentre variability of MRI-based medial temporal lobe volumetry in Alzheimer's disease. Psychiatry Research. 182: 244-50. PMID 20493672 DOI: 10.1016/J.Pscychresns.2010.03.003 |
0.485 |
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| 2010 |
Alexopoulos P, Kurz A, Lewczuk P, Kornhuber J, Wiltfang J, Maier W, Förstl H, Perneczky R. The sortilin-related receptor SORL1 and the amyloid cascade: a possible explanation for the concurrent elevation of CSF soluble APPalpha and APPbeta in Alzheimer's disease. International Journal of Geriatric Psychiatry. 25: 542-3. PMID 20391590 DOI: 10.1002/Gps.2349 |
0.539 |
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| 2010 |
Zimmermann R, Beck G, Knispel S, Maler JM, Weih M, Wiltfang J, Kornhuber J, Lewczuk P. Intrathecal IgG synthesis in patients with alterations in the neurochemical dementia diagnostics. Journal of Alzheimer's Disease. 19: 1199-1203. PMID 20308786 DOI: 10.3233/Jad-2010-1313 |
0.497 |
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| 2010 |
Lewczuk P, Kornhuber J, Vanmechelen E, Peters O, Heuser I, Maier W, Jessen F, Bürger K, Hampel H, Frölich L, Henn F, Falkai P, Rüther E, Jahn H, Luckhaus Ch, ... ... Wiltfang J, et al. Amyloid beta peptides in plasma in early diagnosis of Alzheimer's disease: A multicenter study with multiplexing. Experimental Neurology. 223: 366-70. PMID 19664622 DOI: 10.1016/J.Expneurol.2009.07.024 |
0.564 |
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| 2010 |
Lewczuk P, Kamrowski-Kruck H, Peters O, Heuser I, Jessen F, Popp J, Bürger K, Hampel H, Frölich L, Wolf S, Prinz B, Jahn H, Luckhaus Ch, Perneczky R, Hüll M, ... ... Wiltfang J, et al. Soluble amyloid precursor proteins in the cerebrospinal fluid as novel potential biomarkers of Alzheimer's disease: a multicenter study. Molecular Psychiatry. 15: 138-45. PMID 18663368 DOI: 10.1038/Mp.2008.84 |
0.59 |
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| 2009 |
Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Williams A, Jones N, Thomas C, Stretton A, Morgan AR, Lovestone S, ... ... Wiltfang J, et al. Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nature Genetics. 41: 1088-93. PMID 19734902 DOI: 10.1038/Ng.440 |
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| 2009 |
Lewczuk P, Zimmermann R, Wiltfang J, Kornhuber J. Neurochemical dementia diagnostics: a simple algorithm for interpretation of the CSF biomarkers Journal of Neural Transmission. 116: 1163-1167. PMID 19653063 DOI: 10.1007/S00702-009-0277-Y |
0.444 |
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| 2009 |
Klafki HW, Lewczuk P, Kamrowski-Kruck H, Maler JM, Müller K, Peters O, Heuser I, Jessen F, Popp J, Frölich L, Wolf S, Prinz B, Luckhaus C, Schröder J, Pantel J, ... ... Wiltfang J, et al. Measurement of ERK 1/2 in CSF from patients with neuropsychiatric disorders and evidence for the presence of the activated form. Journal of Alzheimer's Disease : Jad. 18: 613-22. PMID 19625747 DOI: 10.3233/Jad-2009-1167 |
0.533 |
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| 2009 |
Weih M, Krinninger M, Zimmermann R, Lewczuk P, Svitek J, Schaller G, Degirmenci Ü, Richter-Schmidinger T, Wiltfang J, Kuwert T, Kornhuber J, Schmidt D. [Sensitivity of neurochemical dementia diagnostics in CSF compared to 99mTc-SPECT in Alzheimer's dementia]. Fortschritte Der Neurologie Psychiatrie. 77: 407-411. PMID 19582652 DOI: 10.1055/S-0028-1109493 |
0.561 |
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| 2009 |
Jessen F, Gür O, Block W, Ende G, Frölich L, Hammen T, Wiltfang J, Kucinski T, Jahn H, Heun R, Maier W, Kölsch H, Kornhuber J, Träber F. A multicenter (1)H-MRS study of the medial temporal lobe in AD and MCI. Neurology. 72: 1735-40. PMID 19451528 DOI: 10.1212/Wnl.0B013E3181A60A20 |
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| 2009 |
Alexopoulos P, Günther F, Popp J, Jessen F, Peters O, Wolf S, Kneib T, Kurz A, Richter-Schmidinger T, Lewczuk P, Bleich S, Wiltfang J, Kornhuber J. Plasma homocysteine and cerebrospinal fluid neurodegeneration biomarkers in mild cognitive impairment and dementia. Journal of the American Geriatrics Society. 57: 737-9. PMID 19405180 DOI: 10.1111/J.1532-5415.2009.02212.X |
0.41 |
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| 2009 |
Kölsch H, Jessen F, Wiltfang J, Lewczuk P, Dichgans M, Teipel SJ, Kornhuber J, Frölich L, Heuser I, Peters O, Wiese B, Kaduszkiewicz H, van den Bussche H, Hüll M, Kurz A, et al. Association of SORL1 gene variants with Alzheimer's disease. Brain Research. 1264: 1-6. PMID 19368828 DOI: 10.1016/J.Brainres.2009.01.044 |
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| 2009 |
Verwey NA, van der Flier WM, Blennow K, Clark C, Sokolow S, De Deyn PP, Galasko D, Hampel H, Hartmann T, Kapaki E, Lannfelt L, Mehta PD, Parnetti L, Petzold A, Pirttila T, ... ... Wiltfang J, et al. A worldwide multicentre comparison of assays for cerebrospinal fluid biomarkers in Alzheimer's disease. Annals of Clinical Biochemistry. 46: 235-40. PMID 19342441 DOI: 10.1258/Acb.2009.008232 |
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| 2009 |
Kornhuber J, Schmidtke K, Frolich L, Perneczky R, Wolf S, Hampel H, Jessen F, Heuser I, Peters O, Weih M, Jahn H, Luckhaus C, Hüll M, Gertz HJ, Schröder J, ... ... Wiltfang J, et al. Early and differential diagnosis of dementia and mild cognitive impairment: design and cohort baseline characteristics of the German Dementia Competence Network. Dementia and Geriatric Cognitive Disorders. 27: 404-17. PMID 19339779 DOI: 10.1159/000210388 |
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| 2009 |
Weih M, Abu-Omar K, Esselmann H, Gelbrich G, Lewczuk P, Rütten A, Wiltfang J, Kornhuber J. Physical activity and prevention of Alzheimer's dementia: current evidence and feasibility of an interventional trial Fortschritte Der Neurologie-Psychiatrie. 77: 146-151. PMID 19283649 DOI: 10.1055/S-0028-1109068 |
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| 2009 |
Blennow K, De Meyer G, Hansson O, Minthon L, Wallin A, Zetterberg H, Lewczuk P, Vanderstichele H, Vanmechelen E, Kornhuber J, Wiltfang J, Heuser I, Maier W, Luckhaus C, et al. Evolution of Abeta42 and Abeta40 levels and Abeta42/Abeta40 ratio in plasma during progression of Alzheimer's disease: a multicenter assessment. The Journal of Nutrition, Health & Aging. 13: 205-8. PMID 19262954 DOI: 10.1007/S12603-009-0059-0 |
0.516 |
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| 2009 |
Welge V, Fiege O, Lewczuk P, Mollenhauer B, Esselmann H, Klafki H, Wolf S, Trenkwalder C, Otto M, Kornhuber J, Wiltfang J, Bibl M. Combined CSF tau, p-tau181 and amyloid-β 38/40/42 for diagnosing Alzheimer’s disease Journal of Neural Transmission. 116: 203-212. PMID 19142572 DOI: 10.1007/S00702-008-0177-6 |
0.508 |
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| 2009 |
Bibl M, Wiltfang J. [New perspectives in the laboratory diagnosis of dementia]. Der Nervenarzt. 139-46; quiz 147-8. PMID 18931988 DOI: 10.1007/s00115-008-2498-y |
0.333 |
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| 2009 |
Maler JM, Spitzer P, Klafki H, Esselmann H, Lewczuk P, Kornhuber J, Herrmann M, Wiltfang J. Distinct fractional Aβ release patterns in human mononuclear phagocytes Journal of Neuroimmunology. 206: 1-4. PMID 18824266 DOI: 10.1016/J.Jneuroim.2008.08.010 |
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| 2009 |
Smirnov A, Trupp A, Henkel AW, Bloch E, Reulbach U, Lewczuk P, Riggert J, Kornhuber J, Wiltfang J. Differential processing and secretion of Abeta peptides and sAPPalpha in human platelets is regulated by thrombin and prostaglandine 2. Neurobiology of Aging. 30: 1552-62. PMID 18255193 DOI: 10.1016/J.Neurobiolaging.2007.12.009 |
0.48 |
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| 2009 |
Wiltfang J, Lewczuk P, Riederer P, Grünblatt E, Hock C, Scheltens P, Hampel H, Vanderstichele H, Iqbal K, Galasko D, Lannfelt L, Otto M, Esselman H, Henkel AW, Kornhuber J, et al. Consensus paper of the WFSBP task force on biological markers of dementia: The role of CSF and blood analysis in the early and differential diagnosis of dementia | Trabalho de consenso de força-tarefa da WFSBP sobre marcadores biológicos das demências: Contribuição da análise do LCR e do sangue para o diagnóstico precoce e diferencial das demências Revista De Psiquiatria Clinica. 36: 1-16. DOI: 10.1590/S0101-60832009000700001 |
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| 2009 |
Hofmann A, Welge V, Fiege O, Lewczuk P, Wolf S, Mollenhauer B, Wiltfang J, Bibl M. CSF Tau, phospho-Tau181 and amyloid-β 38/40/42 in frontotemporal dementia and pimary progressive aphasia Aktuelle Neurologie. 36. DOI: 10.1055/S-0029-1238452 |
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| 2009 |
Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Williams A, Jones N, Thomas C, Stretton A, Morgan AR, Lovestone S, ... ... Wiltfang J, et al. Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease Nature Genetics. 41: 1156-1156. DOI: 10.1038/Ng1009-1156D |
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| 2009 |
Wiltfang J. Blood and CSF-based neurochemical dementia diagnostics: Current status and perspectives Alzheimers & Dementia. 5: 148. DOI: 10.1016/J.Jalz.2009.05.510 |
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| 2009 |
Jessen F, Träber F, Block W, Gür O, Frölich L, Ende G, Hammen T, Kucinski T, Jahn H, Kornhuber J, Lewczuk P, Wiltfang J. Correlation of CSF biomarkers with 1H-MRS metabolites of the medial temporal lobe in Alzheimer's Disease Alzheimers & Dementia. 5: 126. DOI: 10.1016/J.Jalz.2009.05.425 |
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| 2009 |
Lewczuk P, Zimmermann R, Wiltfang J, Kornhuber J. CSF biomarkers of Alzheimer's disease: An algorithm for interpretation of neurochemical dementia diagnostics analysis Alzheimers & Dementia. 5: 347. DOI: 10.1016/J.Jalz.2009.04.1200 |
0.461 |
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| 2008 |
Bibl M, Lewczuk P, Esselmann H, Mollenhauer B, Klafki HW, Welge V, Wolf S, Trenkwalder C, Otto M, Kornhuber J, Wiltfang J. CSF amyloid-β 1-38 and 1-42 in FTD and AD: Biomarker performance critically depends on the detergent accessible fraction. Proteomics. Clinical Applications. 2: 1548-56. PMID 21136802 DOI: 10.1002/prca.200800006 |
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| 2008 |
Lewczuk P, Hornegger J, Zimmermann R, Otto M, Wiltfang J, Kornhuber J. Neurochemical dementia diagnostics: assays in CSF and blood. European Archives of Psychiatry and Clinical Neuroscience. 258: 44-49. PMID 18985294 DOI: 10.1007/S00406-008-5005-3 |
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| 2008 |
Mamo JCL, Jian l, James AP, Flicker L, Esselmann H, Wiltfang J. Plasma lipoprotein β-amyloid in subjects with Alzheimer's disease or mild cognitive impairment: Annals of Clinical Biochemistry. 45: 395-403. PMID 18583625 DOI: 10.1258/Acb.2008.007214 |
0.458 |
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| 2008 |
Kölsch H, Jessen F, Wiltfang J, Lewczuk P, Dichgans M, Kornhuber J, Frölich L, Heuser I, Peters O, Schulz JB, Schwab SG, Maier W. Influence of SORL1 gene variants: association with CSF amyloid-beta products in probable Alzheimer's disease. Neuroscience Letters. 440: 68-71. PMID 18541377 DOI: 10.1016/J.Neulet.2008.05.049 |
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| 2008 |
Maler JM, Spitzer P, Klafki H, Esselmann H, Bibl M, Lewczuk P, Kornhuber J, Herrmann M, Wiltfang J. Adherence-dependent shifts in the patterns of β-amyloid peptides secreted by human mononuclear phagocytes Brain Behavior and Immunity. 22: 1044-1048. PMID 18511234 DOI: 10.1016/J.Bbi.2008.04.003 |
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| 2008 |
Otto M, Lewczuk P, Wiltfang J. Neurochemical approaches of cerebrospinal fluid diagnostics in neurodegenerative diseases. Methods (San Diego, Calif.). 44: 289-98. PMID 18374272 DOI: 10.1016/j.ymeth.2007.06.012 |
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| 2008 |
Henkel AW, Sperling W, Rotter A, Reulbach U, Reichardt C, Bönsch D, Maler JM, Kornhuber J, Wiltfang J. Antidepressant drugs modulate growth factors in cultured cells. Bmc Pharmacology. 8: 6. PMID 18318898 DOI: 10.1186/1471-2210-8-6 |
0.368 |
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| 2008 |
Hoglund K, Hansson O, Buchhave P, Zetterberg H, Lewczuk P, Londos E, Blennow K, Minthon L, Wiltfang J. Prediction of Alzheimer's disease using a cerebrospinal fluid pattern of C-terminally truncated beta-amyloid peptides Neurodegenerative Diseases. 5: 268-276. PMID 18309230 DOI: 10.1159/000119457 |
0.458 |
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| 2008 |
Lewczuk P, Wiltfang J. Neurochemical dementia diagnostics: State of the art and research perspectives. Proteomics. 8: 1292-301. PMID 18271068 DOI: 10.1002/pmic.200700703 |
0.305 |
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| 2008 |
Bibl M, Mollenhauer B, Esselmann H, Schneider M, Lewczuk P, Welge V, Gross M, Falkai P, Kornhuber J, Wiltfang J. Cerebrospinal fluid neurochemical phenotypes in vascular dementias: original data and mini-review. Dementia and Geriatric Cognitive Disorders. 25: 256-265. PMID 18270488 DOI: 10.1159/000115975 |
0.479 |
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| 2008 |
Lewczuk P, Kornhuber J, Vanderstichele H, Vanmechelen E, Esselmann H, Bibl M, Wolf S, Otto M, Reulbach U, Kölsch H, Jessen F, Schröder J, Schönknecht P, Hampel H, Peters O, ... ... Wiltfang J, et al. Multiplexed quantification of dementia biomarkers in the CSF of patients with early dementias and MCI: a multicenter study. Neurobiology of Aging. 29: 812-8. PMID 17239996 DOI: 10.1016/J.Neurobiolaging.2006.12.010 |
0.545 |
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| 2008 |
Alexopoulos P, Guenther F, Schmidinger TR, Gruss B, Wiltfang J, Bleich S, Kornhuber J. Plasma homocystein levels in relation to β Amyloid and Tau Protein in cerebrospinal fluid of patients with Mild Cognitive Impairment and Alzheimer's Disease Annals of General Psychiatry. 7: 1-1. DOI: 10.1186/1744-859X-7-S1-S185 |
0.586 |
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| 2007 |
Waltereit R, Schulte-Brochterbeck G, Wiltfang J, Frölich L. AIDS dementia complex and Hashimoto encephalopathy in a senescent woman. International Journal of Geriatric Psychiatry. 22: 1267-8. PMID 18033678 DOI: 10.1002/Gps.1820 |
0.348 |
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| 2007 |
Maler JM, Klafki HW, Paul S, Spitzer P, Groemer TW, Henkel AW, Esselmann H, Lewczuk P, Kornhuber J, Wiltfang J. Urea-based two-dimensional electrophoresis of beta-amyloid peptides in human plasma: evidence for novel Abeta species. Proteomics. 7: 3815-20. PMID 17924594 DOI: 10.1002/Pmic.200700311 |
0.463 |
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| 2007 |
Rebelo S, Vieira SI, Esselmann H, Wiltfang J, da Cruz e Silva EF, da Cruz e Silva OA. Tyr687 dependent APP endocytosis and Abeta production. Journal of Molecular Neuroscience : Mn. 32: 1-8. PMID 17873282 DOI: 10.1007/S12031-007-0001-Z |
0.342 |
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| 2007 |
Bibl M, Esselmann H, Mollenhauer B, Weniger G, Welge V, Liess M, Lewczuk P, Otto M, Schulz JB, Trenkwalder C, Kornhuber J, Wiltfang J. Blood-based neurochemical diagnosis of vascular dementia: a pilot study. Journal of Neurochemistry. 103: 467-74. PMID 17662050 DOI: 10.1111/J.1471-4159.2007.04763.X |
0.544 |
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| 2007 |
Kornhuber J, Kennepohl EM, Bleich S, Wiltfang J, Kraus T, Reulbach U, Meineke I. Memantine pharmacotherapy: a naturalistic study using a population pharmacokinetic approach. Clinical Pharmacokinectics. 46: 599-612. PMID 17596105 DOI: 10.2165/00003088-200746070-00005 |
0.302 |
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| 2007 |
Weih M, Wiltfang J, Kornhuber J. Non-pharmacologic prevention of Alzheimer's disease: nutritional and life-style risk factors. Journal of Neural Transmission. 114: 1187-1197. PMID 17557131 DOI: 10.1007/S00702-007-0704-X |
0.427 |
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| 2007 |
Popp J, Thal DR, Lewczuk P, Wiltfang J, Jessen F. Histologically confirmed amyloid deposition and low CSF Aβ42 in a cognitively normal subject Journal of Neurology. 254: 970-971. PMID 17361344 DOI: 10.1007/S00415-006-0445-Z |
0.401 |
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| 2007 |
Bibl M, Mollenhauer B, Lewczuk P, Esselmann H, Wolf S, Trenkwalder C, Otto M, Stiens G, Rüther E, Kornhuber J, Wiltfang J. Validation of amyloid-beta peptides in CSF diagnosis of neurodegenerative dementias. Molecular Psychiatry. 12: 671-680. PMID 17339876 DOI: 10.1038/Sj.Mp.4001967 |
0.591 |
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| 2007 |
Sperling W, Kornhuber J, Wiltfang J, Bleich S. Combined VNS-rTMS treatment in a patient with therapy resistant depression. Pharmacopsychiatry. 40: 39-40. PMID 17327961 DOI: 10.1055/S-2006-958524 |
0.361 |
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| 2007 |
Mollenhauer B, Bibl M, Esselmann H, Steinacker P, Trenkwalder C, Wiltfang J, Otto M. Tauopathies and synucleinopathies: Do cerebrospinal fluid β-amyloid peptides reflect disease-specific pathogenesis? Journal of Neural Transmission. 114: 919-927. PMID 17318305 DOI: 10.1007/S00702-007-0629-4 |
0.417 |
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| 2007 |
Bibl M, Esselmann H, Mollenhauer B, Wiltfang J. Aminoterminally truncated and oxidized amyloid-beta peptide species in Alzheimer's disease. Neuroscience. 146: 17-18. PMID 17317020 DOI: 10.1016/J.Neuroscience.2007.01.010 |
0.362 |
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| 2007 |
Henkel AW, Dittrich PS, Groemer TW, Lemke EA, Klingauf J, Klafki HW, Lewczuk P, Esselmann H, Schwille P, Kornhuber J, Wiltfang J. Immune complexes of auto-antibodies against Aβ1-42 peptides patrol cerebrospinal fluid of non-Alzheimer's patients Molecular Psychiatry. 12: 601-610. PMID 17279093 DOI: 10.1038/Sj.Mp.4001947 |
0.543 |
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| 2007 |
Wiltfang J, Esselmann H, Bibl M, Hüll M, Hampel H, Kessler H, Frölich L, Schröder J, Peters O, Jessen F, Luckhaus C, Perneczky R, Jahn H, Fiszer M, Maler JM, et al. Amyloid beta peptide ratio 42/40 but not A beta 42 correlates with phospho-Tau in patients with low- and high-CSF A beta 40 load. Journal of Neurochemistry. 101: 1053-9. PMID 17254013 DOI: 10.1111/J.1471-4159.2006.04404.X |
0.523 |
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| 2007 |
Bibl M, Mollenhauer B, Wolf S, Esselmann H, Lewczuk P, Kornhuber J, Wiltfang J. Reduced CSF carboxyterminally truncated Aβ peptides in frontotemporal lobe degenerations Journal of Neural Transmission. 114: 621-628. PMID 17245538 DOI: 10.1007/S00702-006-0618-Z |
0.572 |
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| 2007 |
Lehrl S, Gerstmeyer K, Jacob JH, Frieling H, Henkel AW, Meyrer R, Wiltfang J, Kornhuber J, Bleich S. Blue light improves cognitive performance Journal of Neural Transmission. 114: 457-460. PMID 17245536 DOI: 10.1007/S00702-006-0621-4 |
0.372 |
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| 2007 |
Maihöfner C, Sperling W, Kaltenhäuser M, Bleich S, de Zwaan M, Wiltfang J, Thürauf N, Elstner S, Reulbach U, Lewczuk P, Kornhuber J, Ropohl A. Spontaneous magnetoencephalographic activity in patients with obsessive-compulsive disorder Brain Research. 1129: 200-205. PMID 17156764 DOI: 10.1016/J.Brainres.2006.10.048 |
0.407 |
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| 2007 |
Thuerauf N, Lunkenheimer J, Lunkenheimer B, Sperling W, Bleich S, Schlabeck M, Wiltfang J, Kornhuber J. Memantine fails to facilitate partial cigarette deprivation in smokers--no role of Memantine in the treatment of nicotine dependency? Journal of Neural Transmission. 114: 351-357. PMID 17043926 DOI: 10.1007/S00702-006-0570-Y |
0.356 |
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| 2007 |
Maler J, Spitzer P, Lewczuk P, Kornhuber J, Herrmann M, Wiltfang J. Decreases of hematopoietic stem cells in early Alzheimer's disease Pharmacopsychiatry. 40. DOI: 10.1055/S-2007-991811 |
0.47 |
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| 2007 |
Wiltfang J, Bibl M, Maler M, Klafki H-, Esselmann H, Kornhuber J, Lewczuk P. Neurochemische Demenzdiagnostik – Quo vadis? Nervenheilkunde. 26: 861-866. DOI: 10.1055/S-0038-1626937 |
0.387 |
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| 2007 |
Wiltfang J, Bibl M, Maler M, Klafki H-, Esselmann H, Kornhuber J, Lewczuk P. Neurochemische Frühdiagnostik und klinische Neuroproteomik demenzieller Erkrankungen Nervenheilkunde. 26: 853-860. DOI: 10.1055/S-0038-1626936 |
0.338 |
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| 2007 |
Shaw LM, Vanderstichele H, Knapik-Czajka M, Blennow K, Soares H, Simon A, Lewczuk P, Siemers E, Dean R, Raha N, Chappell DL, Wiltfang J, Lachno R, Salfen BE, Lee VM, et al. P-057: Validation of the xMAP technology and performance of INNO-BIA AlzBio3 for quantification in CSF of Aβ1-42
, total tau and P-tau181p Alzheimer's & Dementia. 3: S117-S117. DOI: 10.1016/J.Jalz.2007.04.310 |
0.337 |
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| 2006 |
Lewczuk P, Beck G, Ganslandt O, Esselmann H, Deisenhammer F, Regeniter A, Petereit HF, Tumani H, Gerritzen A, Oschmann P, Schröder J, Schönknecht P, Zimmermann K, Hampel H, Bürger K, ... ... Wiltfang J, et al. International quality control survey of neurochemical dementia diagnostics. Neuroscience Letters. 409: 1-4. PMID 17045397 DOI: 10.1016/J.Neulet.2006.07.009 |
0.54 |
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| 2006 |
Maler JM, Spitzer P, Lewczuk P, Kornhuber J, Herrmann M, Wiltfang J. Decreased circulating CD34+ stem cells in early Alzheimer's disease: Evidence for a deficient hematopoietic brain support? Molecular Psychiatry. 11: 1113-1115. PMID 17033629 DOI: 10.1038/Sj.Mp.4001913 |
0.501 |
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| 2006 |
Klafki H, Staufenbiel M, Kornhuber J, Wiltfang J. Therapeutic approaches to Alzheimer's disease. Brain. 129: 2840-2855. PMID 17018549 DOI: 10.1093/Brain/Awl280 |
0.493 |
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| 2006 |
Bibl M, Mollenhauer B, Esselmann H, Lewczuk P, Trenkwalder C, Brechlin P, Rüther E, Kornhuber J, Otto M, Wiltfang J. CSF diagnosis of Alzheimer’s disease and dementia with Lewy bodies Journal of Neural Transmission. 113: 1771-1778. PMID 16906356 DOI: 10.1007/S00702-006-0537-Z |
0.586 |
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| 2006 |
Lewczuk P, Kornhuber J, Wiltfang J. The German Competence Net Dementias: Standard operating procedures for the neurochemical dementia diagnostics Journal of Neural Transmission. 113: 1075-1080. PMID 16835693 DOI: 10.1007/S00702-006-0511-9 |
0.499 |
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| 2006 |
Kornhuber J, Wiltfang J, Riederer P, Bleich S. Neuroleptic drugs in the human brain: clinical impact of persistence and region-specific distribution. European Archives of Psychiatry and Clinical Neuroscience. 256: 274-280. PMID 16788768 DOI: 10.1007/S00406-006-0661-7 |
0.393 |
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| 2006 |
Bibl M, Mollenhauer B, Esselmann H, Lewczuk P, Klafki HW, Sparbier K, Smirnov A, Cepek L, Trenkwalder C, Rüther E, Kornhuber J, Otto M, Wiltfang J. CSF amyloid-beta-peptides in Alzheimer's disease, dementia with Lewy bodies and Parkinson's disease dementia. Brain : a Journal of Neurology. 129: 1177-87. PMID 16600985 DOI: 10.1093/Brain/Awl063 |
0.48 |
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| 2006 |
Mollenhauer B, Bibl M, Wiltfang J, Steinacker P, Ciesielczyk B, Neubert K, Trenkwalder C, Otto M. Total tau protein, phosphorylated tau (181p) protein, beta-amyloid(1-42), and beta-amyloid(1-40) in cerebrospinal fluid of patients with dementia with Lewy bodies. Clinical Chemistry and Laboratory Medicine. 44: 192-5. PMID 16475906 DOI: 10.1515/CCLM.2006.035 |
0.341 |
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| 2006 |
Lewczuk P, Beck G, Esselmann H, Bruckmoser R, Zimmermann R, Fiszer M, Bibl M, Maler JM, Kornhuber J, Wiltfang J. Effect of Sample Collection Tubes on Cerebrospinal Fluid Concentrations of Tau Proteins and Amyloid β Peptides Clinical Chemistry. 52: 332-334. PMID 16449222 DOI: 10.1373/Clinchem.2005.058776 |
0.537 |
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| 2006 |
Hillemacher T, Bleich S, Wiltfang J, Weber M, Kornhuber J, Frieling H. Should aspirin be discontinued for diagnostic lumbar puncture Journal of the American Geriatrics Society. 54: 181-182. PMID 16420229 DOI: 10.1111/J.1532-5415.2005.00575_12.X |
0.393 |
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| 2006 |
Bentahir M, Nyabi O, Verhamme J, Tolia A, Horré K, Wiltfang J, Esselmann H, De Strooper B. Presenilin clinical mutations can affect gamma-secretase activity by different mechanisms. Journal of Neurochemistry. 96: 732-42. PMID 16405513 DOI: 10.1111/J.1471-4159.2005.03578.X |
0.301 |
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| 2006 |
Henkel AW, Upmann I, Bartl CR, Bönsch D, Reichardt C, Maler JM, Nürnberger M, Umstätter R, Reulbach U, Kornhuber J, Wiltfang J. Light-induced exocytosis in cell development and differentiation. Journal of Cellular Biochemistry. 97: 1393-406. PMID 16365884 DOI: 10.1002/Jcb.20751 |
0.361 |
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| 2006 |
Buerger K, Otto M, Teipel SJ, Zinkowski R, Blennow K, DeBernardis J, Kerkman D, Schröder J, Schönknecht P, Cepek L, McCulloch C, Möller H, Wiltfang J, Kretzschmar H, Hampel H. Dissociation between CSF total tau and tau protein phosphorylated at threonine 231 in Creutzfeldt-Jakob disease. Neurobiology of Aging. 27: 10-15. PMID 16298235 DOI: 10.1016/J.Neurobiolaging.2004.12.003 |
0.416 |
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| 2006 |
Kornhuber J, Weigmann H, Röhrich J, Wiltfang J, Bleich S, Meineke I, Zöchling R, Härtter S, Riederer P, Hiemke C. Region specific distribution of levomepromazine in the human brain. Journal of Neural Transmission. 113: 387-397. PMID 15997416 DOI: 10.1007/S00702-005-0331-3 |
0.38 |
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| 2006 |
Betts MJ, Cardenas-Blanco A, Kanowski M, Wagner M, Heneka M, Spottke A, Teipel SJ, Schneider A, Oliver P, Priller J, Wiltfang J, Laske C, Jessen F, Düzel E. F4-07-03: RELATIONSHIP BETWEEN LOCUS COERULEUS MRI CONTRAST, COGNITION AND CSF BIOMARKERS IN AGING AND ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P1393-P1393. DOI: 10.1016/J.Jalz.2018.06.2890 |
0.384 |
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| 2006 |
Bibl M, Mollenhauer B, Esselmann H, Lewczuk P, Klafki H, Sparbier K, Smirnov A, Cepek L, Trenkwalder C, Ruther E, Kornhuber J, Otto M, Wiltfang J. P2-157: Expression of CSF amyloid beta peptide patterns Alzheimer’s disease, dementia with Lewy bodies and Parkinson’s disease dementia Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.995 |
0.529 |
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| 2006 |
Lewczuk P, Vanderstichele H, Vanmechelen E, Esselmann H, Bibl M, Maler JM, Kornhuber J, Wiltfang J. P2-146: Multiplexed quantification of dementia biomarkers in the cerebrospinal fluid: A multicenter study Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.984 |
0.404 |
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| 2006 |
Maler JM, Klafki HW, Esselmann H, Kunz N, Paul S, Kornhuber J, Wiltfang J. P2-052: Chicken primary neuronal cells as a powerful model for studying tau phosphorylation, APP processing and Aβ generation Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.889 |
0.361 |
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| 2006 |
Svitek J, Lewczuk P, Kornhuber J, Kuwert T, Wiltfang J. P2-219: Mild cognitive impairment: Correlation of Alzheimer‘s disease neurochemical biomarkers with SPECT findings Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1058 |
0.484 |
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| 2006 |
Hoglund K, Hansson O, Buchhave P, Lewzcuk P, Zetterberg H, Blennow K, Minthon L, Wiltfang J. P2-170: The prediction of Alzheimer's disease in patients with mild cognitive impairment using a disease specific pattern of C-terminally truncated β-amyloid peptides Alzheimer's & Dementia. 2: S283-S284. DOI: 10.1016/j.jalz.2006.05.1008 |
0.304 |
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| 2005 |
Kornhuber J, Medlin A, Bleich S, Jendrossek V, Henkel AW, Wiltfang J, Gulbins E. High activity of acid sphingomyelinase in major depression Journal of Neural Transmission. 112: 1583-1590. PMID 16245071 DOI: 10.1007/S00702-005-0374-5 |
0.399 |
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| 2005 |
Wiltfang J, Lewczuk P, Riederer P, Grünblatt E, Hock C, Scheltens P, Hampel H, Vanderstichele H, Iqbal K, Galasko D, Lannfelt L, Otto M, Esselmann H, Henkel AW, Kornhuber J, et al. Consensus paper of the WFSBP Task Force on Biological Markers of Dementia: the role of CSF and blood analysis in the early and differential diagnosis of dementia. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 6: 69-84. PMID 16156480 DOI: 10.1080/15622970510029786 |
0.56 |
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| 2005 |
Maler JM, Esselmann H, Wiltfang J, Kunz N, Lewczuk P, Reulbach U, Bleich S, Rüther E, Kornhuber J. Memantine inhibits ethanol-induced NMDA receptor up-regulation in rat hippocampal neurons. Brain Research. 1052: 156-62. PMID 16009352 DOI: 10.1016/J.Brainres.2005.06.017 |
0.36 |
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| 2005 |
Lotz M, Ebert S, Esselmann H, Iliev AI, Prinz M, Wiazewicz N, Wiltfang J, Gerber J, Nau R. Amyloid beta peptide 1-40 enhances the action of Toll-like receptor-2 and -4 agonists but antagonizes Toll-like receptor-9-induced inflammation in primary mouse microglial cell cultures Journal of Neurochemistry. 94: 289-298. PMID 15998280 DOI: 10.1111/J.1471-4159.2005.03188.X |
0.301 |
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| 2005 |
Höglund K, Syversen S, Lewczuk P, Wallin A, Wiltfang J, Blennow K. Statin treatment and a disease-specific pattern of beta-amyloid peptides in Alzheimer's disease. Experimental Brain Research. 164: 205-14. PMID 15937702 DOI: 10.1007/S00221-005-2243-8 |
0.427 |
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| 2005 |
Mollenhauer B, Bibl M, Trenkwalder C, Stiens G, Cepek L, Steinacker P, Ciesielczyk B, Neubert K, Wiltfang J, Kretzschmar HA, Poser S, Otto M. Follow-up investigations in cerebrospinal fluid of patients with dementia with Lewy bodies and Alzheimer's disease. Journal of Neural Transmission (Vienna, Austria : 1996). 112: 933-48. PMID 15937638 DOI: 10.1007/S00702-004-0235-7 |
0.469 |
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| 2005 |
Mollenhauer B, Cepek L, Bibl M, Wiltfang J, Schulz-Schaeffer WJ, Ciesielczyk B, Neumann M, Steinacker P, Kretzschmar HA, Poser S, Trenkwalder C, Otto M. Tau protein, Abeta42 and S-100B protein in cerebrospinal fluid of patients with dementia with Lewy bodies. Dementia and Geriatric Cognitive Disorders. 19: 164-70. PMID 15637452 DOI: 10.1159/000083178 |
0.362 |
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| 2005 |
Maler JM, Spitzer P, Herrmann M, Esselmann H, Lewczuk P, Kornhuber J, Wiltfang J. β-Amyloid secretion by human monocytes Pharmacopsychiatry. 38. DOI: 10.1055/S-2005-918776 |
0.421 |
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| 2005 |
Maler JM, Esselmann H, Dyrks T, Klafki H, Fiszer M, Paul S, Reulbach U, Lewczuk P, Rüther E, Kornhuber J, Wiltfang J. Specific inhibition of β-amyloid peptide secretion by ZK808762 mimicks the effect of non-steroidal anti-inflammatory drugs Pharmacopsychiatry. 38. DOI: 10.1055/S-2005-918775 |
0.506 |
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| 2005 |
Lewczuk P, Esselmann H, Maler JM, Bibl M, Kornhuber J, Wiltfang J. The concentrations of amyloid beta 1–42, total Tau and phospho-Tau181 in the CSF of patients with early dementia and MCI as measured with multiplexing technology Pharmacopsychiatry. 38. DOI: 10.1055/S-2005-918764 |
0.521 |
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| 2005 |
Mollenhauer B, Trenkwalder C, Sixel-Döring F, Bibl M, Wiltfang J, Poser S, Otto M. Tau-protein und Beta-amyloid (1–42) im Liquor bei Lewy-Body- und Parkinson-Demenz Aktuelle Neurologie. 32: 36. DOI: 10.1055/S-2005-866643 |
0.319 |
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| 2004 |
Esselmann H, Maler JM, Kunz N, Otto M, Paul S, Lewczuk P, Rüther E, Kornhuber J, Wiltfang J. Lithium decreases secretion of Abeta1-42 and C-truncated species Abeta1-37/38/39/40 in chicken telencephalic cultures but specifically increases intracellular Abeta1-38. Neurodegenerative Diseases. 1: 236-241. PMID 16908996 DOI: 10.1159/000080992 |
0.478 |
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| 2004 |
Kornhuber J, Wiltfang J, Bleich S. The etiopathogenesis of schizophrenias. Pharmacopsychiatry. 37: 103-112. PMID 15546061 DOI: 10.1055/S-2004-832663 |
0.364 |
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| 2004 |
Lewczuk P, Esselmann H, Bibl M, Paul S, Svitek J, Miertschischk J, Meyrer R, Smirnov A, Maler JM, Klein C, Otto M, Bleich S, Sperling W, Kornhuber J, Rüther E, ... Wiltfang J, et al. Electrophoretic separation of amyloid β peptides in plasma Electrophoresis. 25: 3336-3343. PMID 15490456 DOI: 10.1002/Elps.200406068 |
0.484 |
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| 2004 |
Bibl M, Esselmann H, Otto M, Lewczuk P, Cepek L, Rüther E, Kornhuber J, Wiltfang J. Cerebrospinal fluid amyloid beta peptide patterns in Alzheimer's disease patients and nondemented controls depend on sample pretreatment: indication of carrier-mediated epitope masking of amyloid beta peptides. Electrophoresis. 25: 2912-8. PMID 15349929 DOI: 10.1002/Elps.200305992 |
0.506 |
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| 2004 |
Lewczuk P, Esselmann H, Bibl M, Beck G, Maler JM, Otto M, Kornhuber J, Wiltfang J. Tau protein phosphorylated at threonine 181 in CSF as a neurochemical biomarker in Alzheimer’s disease Journal of Molecular Neuroscience. 23: 115-122. PMID 15126697 DOI: 10.1385/Jmn:23:1-2:115 |
0.536 |
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| 2004 |
Lewczuk P, Esselmann H, Otto M, Maler JM, Henkel AW, Henkel MK, Eikenberg O, Antz C, Krause WR, Reulbach U, Kornhuber J, Wiltfang J. Neurochemical diagnosis of Alzheimer's dementia by CSF Abeta42, Abeta42/Abeta40 ratio and total tau. Neurobiology of Aging. 25: 273-81. PMID 15123331 DOI: 10.1016/S0197-4580(03)00086-1 |
0.571 |
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| 2004 |
Lewczuk P, Esselmann H, Groemer TW, Bibl M, Maler JM, Steinacker P, Otto M, Kornhuber J, Wiltfang J. Amyloid β peptides in cerebrospinal fluid as profiled with surface enhanced laser desorption/ionization time-of-flight mass spectrometry: evidence of novel biomarkers in Alzheimer's disease Biological Psychiatry. 55: 524-530. PMID 15023581 DOI: 10.1016/J.Biopsych.2003.10.014 |
0.545 |
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| 2004 |
Otto M, Cepek L, Ratzka P, Doehlinger S, Boekhoff I, Wiltfang J, Irle E, Pergande G, Ellers-Lenz B, Windl O, Kretzschmar HA, Poser S, Prange H. Efficacy of flupirtine on cognitive function in patients with CJD: A double-blind study. Neurology. 62: 714-8. PMID 15007119 DOI: 10.1212/01.Wnl.0000113764.35026.Ef |
0.33 |
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| 2004 |
Hampel H, Teipel SJ, Fuchsberger T, Andreasen N, Wiltfang J, Otto M, Shen Y, Dodel R, Du Y, Farlow M, Möller HJ, Blennow K, Buerger K. Value of CSF β-amyloid1-42 and tau as predictors of Alzheimer's disease in patients with mild cognitive impairment Molecular Psychiatry. 9: 705-710. PMID 14699432 DOI: 10.1038/Sj.Mp.4001473 |
0.49 |
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| 2004 |
Wiltfang J, Lewczuk P, Maler M, Smirnov A, Kornhuber J. Neurochemical early and differential diagnosis of Alzheimer’s dementia Pharmacopsychiatry. 36: 314. DOI: 10.1055/S-2003-825557 |
0.465 |
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| 2004 |
Thürauf N, Lunkenheimer J, Sperling W, Bleich S, Wiltfang J, Plodeck V, Wuttke H, Rau T, Eschenhagen T, Kornhuber J. CYP2D6-Genotyping in clinical practice: Impact of Genotyp on serum concentrations of psychiatric relevant CYP2D6-substrates Pharmacopsychiatry. 36. DOI: 10.1055/S-2003-825532 |
0.385 |
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| 2004 |
Esselmann H, Kunz N, Maler JM, Lewczuk P, Otto M, Ruether E, Kornhuber J, Wiltfang J. O4-04-03 Lithium decreases secretion of Abeta 1–42 and C-truncated species Abeta 1-37/38/39/40 in chicken telencephalic cultures but specifically increases intracellular Abeta 1–38 Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80274-4 |
0.333 |
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| 2004 |
Wiltfang J, Esselmann H, Bibl M, Kornhuber J, Lewczuk P. S1-02-03 Neuroproteomic profiling of amyloid beta peptides in human CSF with SELDI-TOF MS Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80012-5 |
0.359 |
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| 2003 |
Bleich S, Römer K, Wiltfang J, Kornhuber J. Glutamate and the glutamate receptor system: a target for drug action International Journal of Geriatric Psychiatry. 18. PMID 12973748 DOI: 10.1002/Gps.933 |
0.421 |
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| 2003 |
Bleich S, Wiltfang J, Kornhuber J. Memantine in moderate-to-severe Alzheimer's disease. The New England Journal of Medicine. 349: 609. PMID 12904528 DOI: 10.1056/Nejm200308073490616 |
0.445 |
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| 2003 |
Wiltfang J, Esselmann H, Smirnov A, Bibl M, Cepek L, Steinacker P, Mollenhauer B, Buerger K, Hampel H, Paul S, Neumann M, Maler M, Zerr I, Kornhuber J, Kretzschmar HA, et al. Beta-amyloid peptides in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. Annals of Neurology. 54: 263-7. PMID 12891683 DOI: 10.1002/Ana.10661 |
0.484 |
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| 2003 |
Maler JM, Seifert W, Hüther G, Wiltfang J, Rüther E, Kornhuber J, Bleich S. Homocysteine induces cell death of rat astrocytes in vitro. Neuroscience Letters. 347: 85-8. PMID 12873734 DOI: 10.1016/S0304-3940(03)00655-4 |
0.425 |
|
| 2003 |
Lewczuk P, Esselmann H, Meyer M, Wollscheid V, Neumann M, Otto M, Maler JM, Rüther E, Kornhuber J, Wiltfang J. The amyloid-beta (Abeta) peptide pattern in cerebrospinal fluid in Alzheimer's disease: evidence of a novel carboxyterminally elongated Abeta peptide. Rapid Communications in Mass Spectrometry : Rcm. 17: 1291-6. PMID 12811752 DOI: 10.1002/Rcm.1048 |
0.499 |
|
| 2003 |
Riemenschneider M, Wagenpfeil S, Vanderstichele H, Otto M, Wiltfang J, Kretzschmar H, Vanmechelen E, Förstl H, Kurz A. Phospho-tau/total tau ratio in cerebrospinal fluid discriminates Creutzfeldt-Jakob disease from other dementias. Molecular Psychiatry. 8: 343-7. PMID 12660807 DOI: 10.1038/Sj.Mp.4001220 |
0.454 |
|
| 2003 |
Maler M, Wiltfang J, Degner D, Kornhuber J, Bleich S. P.4.050 Homocysteine induces cell death of astrocytes in vitro European Neuropsychopharmacology. 13. DOI: 10.1016/S0924-977X(03)92244-9 |
0.365 |
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| 2002 |
Maeck L, Meller J, Otto M, Stiens G, Wiltfang J, Stoppe G. Abeta peptide 1-42, Tau protein and S-100B protein level in cerebrospinal fluid of three patients with primary progressive aphasia. Neuroscience Letters. 333: 33-6. PMID 12401554 DOI: 10.1016/S0304-3940(02)00968-0 |
0.411 |
|
| 2002 |
Baxter HC, Fraser JR, Liu WG, Forster JL, Clokie S, Steinacker P, Otto M, Bahn E, Wiltfang J, Aitken A. Specific 14-3-3 isoform detection and immunolocalization in prion diseases Biochemical Society Transactions. 30: 387-391. PMID 12196100 DOI: 10.1042/Bst0300387 |
0.336 |
|
| 2002 |
Wiltfang J, Esselmann H, Bibl M, Smirnov A, Otto M, Paul S, Schmidt B, Klafki H-, Maler M, Dyrks T, Bienert M, Beyermann M, Rüther E, Kornhuber J. Highly conserved and disease‐specific patterns of carboxyterminally truncated Aβ peptides 1–37/38/39 in addition to 1–40/42 in Alzheimer's disease and in patients with chronic neuroinflammation Journal of Neurochemistry. 81: 481-496. PMID 12065657 DOI: 10.1046/J.1471-4159.2002.00818.X |
0.532 |
|
| 2002 |
Otto M, Wiltfang J, Cepek L, Neumann M, Mollenhauer B, Steinacker P, Ciesielczyk B, Schulz-Schaeffer W, Kretzschmar HA, Poser S. Tau protein and 14-3-3 protein in the differential diagnosis of Creutzfeldt-Jakob disease. Neurology. 58: 192-7. PMID 11805244 DOI: 10.1212/Wnl.58.2.192 |
0.354 |
|
| 2002 |
Kornhuber J, Wiltfang J. Women and dementia European Psychiatry. 17: 28. DOI: 10.1016/S0924-9338(02)80126-2 |
0.325 |
|
| 2001 |
Bleich S, Bleich K, Wiltfang J, Maler JM, Kornhuber J. Glutamaterge Neurotransmission bei Schizophrenien Fortschritte Der Neurologie Psychiatrie. 69: 56-61. PMID 11533851 DOI: 10.1055/S-2001-16531 |
0.371 |
|
| 2001 |
Wiltfang J, Esselmann H, Cupers P, Neumann M, Kretzschmar H, Beyermann M, Schleuder D, Jahn H, Rüther E, Kornhuber J, Annaert W, De Strooper B, Saftig P. Elevation of beta-amyloid peptide 2-42 in sporadic and familial Alzheimer's disease and its generation in PS1 knockout cells. The Journal of Biological Chemistry. 276: 42645-57. PMID 11526104 DOI: 10.1074/Jbc.M102790200 |
0.478 |
|
| 2001 |
Itoh N, Arai H, Urakami K, Ishiguro K, Ohno H, Hampel H, Buerger K, Wiltfang J, Otto M, Kretzschmar H, Moeller HJ, Imagawa M, Kohno H, Nakashima K, Kuzuhara S, et al. Large-scale, multicenter study of cerebrospinal fluid tau protein phosphorylated at serine 199 for the antemortem diagnosis of Alzheimer's disease. Annals of Neurology. 50: 150-6. PMID 11506396 DOI: 10.1002/Ana.1054 |
0.351 |
|
| 2001 |
Wiltfang J, Esselmann H, Maler JM, Bleich S, Hüther G, Kornhuber J. Molecular biology of Alzheimer's dementia and its clinical relevance to early diagnosis and new therapeutic strategies. Gerontology. 47: 65-71. PMID 11287729 DOI: 10.1159/000052775 |
0.516 |
|
| 2000 |
Bleich S, Spilker K, Kurth C, Degner D, Quintela-Schneider M, Javaheripour K, Rüther E, Kornhuber J, Wiltfang J. Oxidative stress and an altered methionine metabolism in alcoholism. Neuroscience Letters. 293: 171-4. PMID 11036188 DOI: 10.1016/S0304-3940(00)01505-6 |
0.391 |
|
| 2000 |
Bleich S, Kropp S, Degner D, Zerr I, Pilz J, Gleiter CH, Otto M, Rüther E, Kretzschmar HA, Wiltfang J, Kornhuber J, Poser S. Creutzfeldt-Jakob disease and oxidative stress. Acta Neurologica Scandinavica. 101: 332-4. PMID 10987323 DOI: 10.1034/J.1600-0404.2000.9S290A.X |
0.401 |
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| 2000 |
Kropp S, Schlimme J, Bleich S, Wiltfang J, Dietrich DE, Emrich HM. Diagnostische Schritte bei Alzheimer-Demenz vor Therapiebeginn mit neuen Antidementiva Fortschritte Der Neurologie Psychiatrie. 68: 257-261. PMID 10923250 DOI: 10.1055/S-2000-11808 |
0.426 |
|
| 2000 |
Bleich S, Degner D, Wiltfang J, Maler JM, Niedmann P, Cohrs S, Mangholz A, Porzig J, Sprung R, Rüther E, Kornhuber J. Elevated homocysteine levels in alcohol withdrawal. Alcohol and Alcoholism. 35: 351-354. PMID 10905999 DOI: 10.1093/Alcalc/35.4.351 |
0.369 |
|
| 2000 |
Otto M, Esselmann H, Schulz-Shaeffer W, Neumann M, Schröter A, Ratzka P, Cepek L, Zerr I, Steinacker P, Windl O, Kornhuber J, Kretzschmar HA, Poser S, Wiltfang J. Decreased beta-amyloid1-42 in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. Neurology. 54: 1099-102. PMID 10720281 DOI: 10.1212/Wnl.54.5.1099 |
0.549 |
|
| 2000 |
Kornhuber J, Bleich S, Wiltfang J. PCP-site ligands and the glutamate hypothesis of schizophrenia European Neuropsychopharmacology. 10: 211. DOI: 10.1016/S0924-977X(00)80124-8 |
0.341 |
|
| 1999 |
Kornhuber J, Bleich S, Wiltfang J, Maler M, Parsons CG. Flupirtine shows functional NMDA receptor antagonism by enhancing Mg2+ block via activation of voltage independent potassium channels Journal of Neural Transmission. 106: 857-867. PMID 10599868 DOI: 10.1007/S007020050206 |
0.377 |
|
| 1999 |
Kornhuber J, Maler M, Wiltfang J, Bleich S, Degner D, Rüther E. Neuronale Kaliumkanalöffnung durch Flupirtin Fortschritte Der Neurologie Psychiatrie. 67: 466-475. PMID 10596368 DOI: 10.1055/S-2007-994997 |
0.369 |
|
| 1999 |
Wiltfang J, Otto M, Baxter HC, Bodemer M, Steinacker P, Bahn E, Zerr I, Kornhuber J, Kretzschmar HA, Poser S, Rüther E, Aitken A. Isoform pattern of 14-3-3 proteins in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. Journal of Neurochemistry. 73: 2485-90. PMID 10582609 DOI: 10.1046/J.1471-4159.1999.0732485.X |
0.522 |
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| 1999 |
Otto M, Wiltfang J, Poser S, Kornhuber J, Burger K, Padberg F, Moller HJ, Hampel H. Tau protein: A potential biological indicator for early recognition of Alzheimer's disease [1] (multiple letters) Nervenarzt. 70: 668-670. PMID 10434268 DOI: 10.1007/S001150050494 |
0.517 |
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| 1999 |
Kornhuber J, Jellinger K, Wiltfang J, Leblhuber F, Riederer P. The N-methyl-D-aspartate receptor channel blocker amantadine does not cause histopathological alterations in human brain tissue. Acta Neuropathologica. 98: 85-90. PMID 10412804 DOI: 10.1007/S004010051054 |
0.411 |
|
| 1999 |
Kornhuber J, Schultz A, Wiltfang J, Meineke I, Gleiter CH, Zöchling R, Boissl K, Leblhuber F, Riederer P. Persistence of haloperidol in human brain tissue. American Journal of Psychiatry. 156: 885-890. PMID 10360127 DOI: 10.1176/Ajp.156.6.885 |
0.305 |
|
| 1999 |
Hulstaert F, Blennow K, Ivanoiu A, Schoonderwaldt HC, Riemenschneider M, De Deyn PP, Bancher C, Cras P, Wiltfang J, Mehta PD, Iqbal K, Pottel H, Vanmechelen E, Vanderstichele H. Improved discrimination of AD patients using beta-amyloid(1-42) and tau levels in CSF. Neurology. 52: 1555-62. PMID 10331678 DOI: 10.1212/Wnl.52.8.1555 |
0.414 |
|
| 1998 |
Wiltfang J, Nolte W, Weissenborn K, Kornhuber J, Rüther E. Psychiatric aspects of portal-systemic encephalopathy. Metabolic Brain Disease. 13: 379-389. PMID 10206828 DOI: 10.1023/A:1020697127718 |
0.406 |
|
| 1998 |
Otto M, Beekes M, Wiltfang J, Bahn E, Poser S, Diringer H. Elevated levels of serum S100 beta protein in scrapie hamsters [1] Journal of Neurovirology. 4: 572-573. PMID 9839656 DOI: 10.3109/13550289809113503 |
0.308 |
|
| 1998 |
Kornhuber J, Wiltfang J, Kornbuber J. The role of glutamate in dementia. Journal of Neural Transmission. Supplementum. 53: 277-87. PMID 9700664 DOI: 10.1007/978-3-7091-6467-9_24 |
0.316 |
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| 1998 |
Zerr I, Bodemer M, Gefeller O, Otto M, Poser S, Wiltfang J, Windl O, Kretzschmar HA, Weber T. Detection of 14-3-3 protein in the cerebrospinal fluid supports the diagnosis of Creutzfeldt-Jakob disease. Annals of Neurology. 43: 32-40. PMID 9450766 DOI: 10.1002/Ana.410430109 |
0.325 |
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| 1997 |
Wiltfang J, Smirnov A, Schnierstein B, Kelemen G, Matthies U, Klafki H, Staufenbiel M, Hüther G, Rüther E, Kornhuber J. Improved electrophoretic separation and immunoblotting of beta‐amyloid (Aβ) peptides 1–40, 1–42, and 1–43 Electrophoresis. 18: 527-532. PMID 9150936 DOI: 10.1002/Elps.1150180332 |
0.449 |
|
| 1997 |
Otto M, Wiltfang J, Tumani H, Zerr I, Lantsch M, Kornhuber J, Weber T, Kretzschmar HA, Poser S. Elevated levels of tau-protein in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. Neuroscience Letters. 225: 210-2. PMID 9147407 DOI: 10.1016/S0304-3940(97)00215-2 |
0.496 |
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